Heat dissipation mechanism, electrode plate for tumor electric field treatment and treatment system

Abstract

The invention relates to the technical field of tumor electric field treatment, in particular to a heat dissipation mechanism, an electrode plate for tumor electric field treatment and a treatment system. The heat dissipation mechanism is used for an electrode plate, and comprises a heat dissipation piece which is connected with the electrode plate to form a heat exchange space, and the heat exchange space is provided with an inlet and an outlet for a heat exchange medium to circulate, so that the heat exchange medium in the heat exchange space exchanges heat with the electrode plate. According to the heat dissipation mechanism provided by the embodiment of the invention, the heat exchange space is formed on the surface of the electrode plate, and the heat exchange medium exchanges heat with the electrode plate, so that the temperature of the electrode plate is reduced, the heat dissipation problem of the electrode plate is solved, and the comfort in the treatment process is improved.

Description

Technical Field

[0001] The present application relates to the technical field of electric field therapy for tumors, and in particular to a heat dissipation mechanism, an electrode sheet for electric field therapy for tumors, and a treatment system. Background Art

[0002] There are many technical means to treat tumors, such as surgery, radiotherapy, chemotherapy, molecular targeted therapy, immunotherapy, interventional therapy, etc. These treatment methods have many disadvantages. For example, they need to be treated in a specific place and under a specific environment. They may also cause varying degrees of damage to the human body and may even require the placement of drug infusion lines in the human body. Existing treatment methods are difficult to treat, have large side effects, are prone to secondary injuries, and affect normal life.

[0003] At present, tumor electric field therapy has become one of the important research and development directions of tumor treatment due to its advantages such as non-invasiveness, portability, easy operation, and no need for specific environmental requirements. Tumor electric field therapy applies an alternating electric field to the treatment site of the human body, affecting the aggregation of tumor microtubules and preventing spindle formation, thereby inhibiting the mitotic process of cancer cells and inducing apoptosis of cancer cells. Specifically, the existing tumor electric field therapy mainly attaches electrodes to the surface of the patient's body, such as on opposite sides of the treatment site, and applies an alternating electric field to the treatment site through the electrodes on opposite sides, thereby achieving the purpose of tumor treatment.

[0004] The electrode sheet generates heat during operation and easily causes sweating on the skin of the contact area, which reduces the comfort of the treatment process. Due to the small size of the electrode sheet (small surface area and small thickness), it is not convenient to arrange a heat dissipation device for active heat dissipation. At present, how to solve the heat dissipation problem of the electrode sheet and improve the comfort of the treatment process is one of the important research directions in this field. Summary of the invention

[0005] The present application aims to provide a heat dissipation mechanism, an electrode sheet for tumor electric field therapy, and a treatment system to solve the heat dissipation problem of the electrode sheet and improve the comfort of the treatment process.

[0006] The embodiment of the present application is implemented as follows:

[0007] In a first aspect, an embodiment of the present application provides a heat dissipation mechanism, which includes:

[0008] A heat sink is connected to the electrode sheet to form a heat exchange space, wherein the heat exchange space has an inlet and an outlet for heat exchange medium to flow through, so that the heat exchange medium in the heat exchange space can exchange heat with the electrode sheet.

[0009] The heat dissipation mechanism provided in the embodiment of the present application forms a heat exchange space on the surface of the electrode sheet for the circulation of a heat exchange medium, so that the heat exchange medium and the surface of the electrode sheet can exchange heat, thereby reducing the temperature of the electrode sheet, solving the heat dissipation problem of the electrode sheet, and improving the comfort of the treatment process.

[0010] In one embodiment of the present application, the heat dissipation mechanism further includes:

[0011] The substrate is arranged on a side of the heat sink facing the electrode sheet. The heat sink is connected to the electrode sheet through the substrate. The heat exchange space is formed between the substrate and the heat sink.

[0012] In the above technical solution, the substrate and the heat sink can be pre-fabricated as one piece and then pasted to the surface of the electrode sheet, which is convenient for production and maintenance and replacement; at the same time, the substrate, as a structure connecting the heat sink and the electrode sheet, not only plays a connecting role, but also can protect the electrode sheet when it is bent and deformed, thereby further ensuring the stability of the connection between the heat sink and the electrode sheet.

[0013] In one embodiment of the present application, the substrate includes a hollow area, and the hollow area is used to expose the electrode sheet to the heat exchange space.

[0014] In the above technical solution, while ensuring the stability of the connection between the heat sink and the electrode sheet, the heat exchange medium and the electrode sheet directly exchange heat, which is beneficial to improving the heat exchange efficiency.

[0015] In one embodiment of the present application, the hollow area is provided with a plurality of through holes or through grooves, and the plurality of through holes or through grooves are evenly distributed in the hollow area.

[0016] In the above technical solution, a plurality of evenly distributed through holes or through grooves are provided to make the heat exchange of the electrode sheet as uniform as possible.

[0017] In one embodiment of the present application, the substrate further includes an edge region, the edge region is surrounded by the hollow region, and the edge region is sealedly connected to the electrode sheet and the heat sink.

[0018] In the above technical solution, the hollow area is surrounded by an edge area, and the heat sink is connected to the edge area and covers the hollow area.

[0019] In one embodiment of the present application, the heat sink includes a connecting portion and a covering portion, the connecting portion is connected to the edge area, and the heat exchange space is formed between the covering portion and the hollow area.

[0020] In the above technical solution, a heat exchange space is formed between the covering portion and the hollow area. When a sealed connection is adopted between the connecting portion and the edge area, it is convenient to preset the inlet and outlet positions of the heat exchange medium on the covering portion, the substrate or the electrode sheet, thereby adjusting the flow path and residence time of the heat exchange medium in the heat exchange space.

[0021] In an embodiment of the present application, in the heat dissipation element, at least the covering portion is made of a flexible material or an elastic material.

[0022] In the above technical solution, when the covering part is made of flexible material, the obstruction to the heat exchange medium is small, the heat exchange medium is easy to flow in the heat exchange space, and the covering part is easy to bulge under the squeeze of the heat exchange medium to form an expanded heat exchange space; when the covering part is made of elastic material, it can be flatly attached to the hollow area when not in use, without occupying additional space. After the heat exchange medium enters the heat exchange space, it can overcome the elastic force of the covering part, so that the surface area of ​​the covering part is increased and arched, thereby increasing the heat exchange space.

[0023] In one embodiment of the present application, the inlet and the outlet are arranged on the covering portion.

[0024] Compared with setting the inlet and outlet at the connecting part, in the above technical solution, by setting the inlet and outlet at the covering part opposite to the hollow area, the new heat exchange medium can flow toward the electrode sheet after entering the heat exchange space, and the original heat exchange medium can be squeezed away from the electrode sheet, thereby forming an efficient heat exchange flow path and improving the heat exchange effect.

[0025] In one embodiment of the present application, the inlet is arranged in the middle of the covering portion.

[0026] In the above technical solution, by setting the inlet in the middle of the covering part, after the heat exchange medium enters the heat exchange space, it first flows toward the center of the electrode sheet, which is beneficial to accelerate the heat dissipation of the middle position of the electrode sheet.

[0027] In an embodiment of the present application, the outlet is closer to the edge of the covering portion than the inlet.

[0028] In the above technical solution, by arranging the outlet and inlet at the edge to cooperate, the heat exchange medium is guided to flow from the middle to the edge and then flow out in the direction away from the electrode sheet, ensuring that the edge position of the electrode sheet is also fully cooled.

[0029] In one embodiment of the present application, the substrate includes an insulating layer and an adhesive layer, the insulating layer is connected to the electrode sheet through the adhesive layer, and the hollow portion of the hollow area passes through the insulating layer to the electrode sheet.

[0030] In the above technical solution, through holes are set on the substrate to penetrate the insulating layer and the adhesive layer before pasting. On the one hand, the connection force between the substrate and the electrode sheet is ensured, and on the other hand, the through holes (especially micropores) set in the hollow part are prevented from being blocked by the adhesive, thereby ensuring that the heat exchange medium can contact and exchange heat with the electrode sheet through the hollow part.

[0031] In one embodiment of the present application, the heat dissipation mechanism further includes: a heat exchange medium source, which is used to introduce heat exchange medium into the heat exchange space.

[0032] In a second aspect, an embodiment of the present application provides an electrode sheet for tumor electric field therapy, comprising:

[0033] Dielectric layer;

[0034] An electrode layer, disposed on one side of the dielectric layer;

[0035] The heat dissipation mechanism according to any one of the first aspects, wherein a base of the heat dissipation mechanism is connected to the electrode layer.

[0036] The electrode sheet provided in the present application has the aforementioned heat dissipation mechanism, so it has a good skin feel and the treatment process is more comfortable.

[0037] In a third aspect, an embodiment of the present application provides a treatment system for tumor electric field therapy, comprising:

[0038] at least one pair of electrode sheets as described in the second aspect; and

[0039] A heat dissipation mechanism is a generator that produces a tumor therapeutic electric field.

[0040] The therapeutic system for electric field therapy of tumors provided in the present application has electrodes with good skin feel, which makes it easy for patients to use it for a long time and achieves good therapeutic effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0041] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0042] Figure 1 A schematic diagram of a treatment system for tumor electric field therapy provided by an embodiment of the present application;

[0043] Figure 2 A schematic diagram of a treatment system for tumor electric field therapy provided by another embodiment of the present application;

[0044] Figure 3A schematic diagram of the cross-sectional structure of an electrode sheet provided in one embodiment of the present application;

[0045] Figure 4 A schematic cross-sectional view of an electrode sheet with a substrate provided in one embodiment of the present application;

[0046] Figure 5 A schematic diagram of the planar structure of a substrate provided in one embodiment of the present application;

[0047] Figure 6 A schematic diagram of a planar structure of a substrate provided in another embodiment of the present application;

[0048] Figure 7 A schematic diagram of a hollow area provided in an embodiment of the present application being enclosed by an edge area;

[0049] Figure 8 A schematic diagram of the heat exchange medium entering the non-hollowed-out part of the hollowed-out area and between the electrode sheets;

[0050] Fig. 9 A state diagram of a heat dissipation mechanism provided in an embodiment of the present application during use;

[0051] Fig.10 A state diagram of a heat dissipation mechanism provided in an embodiment of the present application when it is not in use;

[0052] Fig.11 A schematic diagram of the cross-sectional structure of an electrode sheet provided in another embodiment of the present application;

[0053] Fig.12 A schematic diagram of the connection structure between the connecting pipe and the inlet of the heat exchange space provided in one embodiment of the present application.

[0054] Icon: 1000-treatment system, 100-electrode sheet, 101-dielectric layer, 102-electrode layer, 103-heat dissipation mechanism, 201-storage mechanism, 202-power mechanism, 203-air dynamic pump, 1-base, 11-hollow area, 111-through hole, 12-edge area, 1a-insulating layer, 1b-adhesive layer, 2-heat dissipation part, 21-connecting part, 22-covering part, 3-heat exchange space, 4-inlet, 5-outlet, 6-connecting pipe, 7-elastic sleeve. DETAILED DESCRIPTION

[0055] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative work are within the scope of protection of the present invention.

[0056] In the description of the present invention, it should be understood that the terms "center", "width", "thickness", "upper", "lower", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present invention, the meaning of "multiple" is two or more, unless otherwise clearly and specifically defined.

[0057] In this application, the word "exemplary" is used to mean "serving as an example, illustration, or illustration." Any embodiment described in this application as "exemplary" is not necessarily to be construed as being preferred or advantageous over other embodiments. The following description is given to enable any person skilled in the art to implement and use the invention. In the following description, details are listed for the purpose of explanation. It should be understood that a person of ordinary skill in the art can recognize that the invention can be implemented without using these specific details. In other instances, well-known structures and processes are not elaborated in detail to avoid obscuring the description of the invention with unnecessary details. Therefore, the present invention is not intended to be limited to the embodiments shown, but is consistent with the widest scope consistent with the principles and features disclosed in this application.

[0058] The embodiments of the present application relate to the technical field of tumor electric field therapy, which is a new means of treating cancer. It utilizes the differentiated characteristics that most normal cells are in a dormant phase while tumor cells proliferate rapidly (the electric field distribution in normal cells is uniform, while the electric field distribution in tumor cells is uneven) to apply an alternating electric field of a specific intensity to the human lesion to inhibit tumor cell mitosis, cause tumor cell apoptosis and inhibit tumor growth.

[0059] Electrode sheets are important devices in electric field therapy for tumors. Two or more electrode sheets are attached to the surface of the human body, and an alternating electric field is applied to the treatment site through the two electrode sheets, thereby achieving the purpose of treating the tumor.

[0060] The electrodes will generate heat during operation and easily cause sweating on the skin of the contact area, which will reduce the comfort of the treatment process. In order to improve the discomfort caused by the heating of the electrodes and the sweating of the skin, there are currently many main methods used, such as:

[0061] A semiconductor cooling sheet is arranged on the side of the electrode sheet facing away from the skin. The semiconductor cooling sheet can improve the heat conducted from the electrode sheet to the skin to a certain extent, but the semiconductor cooling sheet will inevitably generate heat while cooling, and the heat generated by the semiconductor cooling sheet may also act on the electrode sheet or the human body, so the heat dissipation effect is limited.

[0062] When there are multiple electrode sheets, adjacent electrode sheets are spaced apart to facilitate dehumidification and ventilation. This method can alleviate the problem of concentrated release of heat generated by multiple electrode sheets, but it does not fundamentally solve the heat problem of the electrode sheets, and the area covered by the electrode sheets is still relatively hot.

[0063] There is also a method of cooling by using liquid cooling pipes, but due to the small area and thin thickness of the electrode sheet, the liquid cooling pipes are not convenient to connect to the electrode sheet. The liquid cooling pipes are generally arranged around the outer circumference of the electrode sheet. Although it has a certain cooling effect, the pipeline layout is complicated and sometimes it may hinder the complete fit of the electrode sheet to the skin, thereby having a negative impact on the effect of electric field therapy.

[0064] The embodiments of the present application provide a heat dissipation mechanism, an electrode sheet for electric field therapy of tumors, and a treatment system, which can reduce the temperature of the electrode sheet and solve the heat dissipation problem of the electrode sheet. The structure is simple, does not affect the fit between the electrode sheet and the skin, and can improve the comfort of the treatment process.

[0065] The treatment system comprises a generator and at least one pair of the aforementioned electrode sheets, wherein the generator is used to connect the electrode sheets and generate an electric field for treating the tumor.

[0066] like Figure 3 As shown, the electrode sheet 100 includes an electrode layer 102 , a dielectric layer 101 and a heat dissipation mechanism 103 . The electrode layer 102 and the dielectric layer 101 are stacked, and the heat dissipation mechanism 103 is disposed on the electrode layer 102 .

[0067] The electrode layer 102 is made of a conductive material, and the electrode layer 102 is connected to an AC power source to facilitate the input of an AC voltage signal. In some embodiments, the electrode layer 102 can be a thin and flexible metal layer, such as a metal copper foil with a thickness of 0.1 mm to 1 mm, so that the electrode layer 102 is flexible and easy to bend, thereby making the film capacitor bend as a whole and completely close to the skin surface of the human body. It can be understood that the electrode layer 102 can also be made of other metal materials or non-metallic materials, such as metal silver foil or conductive graphite.

[0068] The dielectric layer 101 is made of insulating material, which can prevent current from flowing through, thereby preventing the current connected to the electrode layer 102 of the electrode sheet 100 from directly acting on the human body.

[0069] The heat dissipation mechanism 103 in the embodiment of the present application is used to adjust the temperature of the electrode sheet 100, for example, to dissipate heat and cool down the electrode sheet 100 or to heat up the electrode sheet 100 so that the electrode sheet 100 reaches a suitable skin-feeling temperature. Figure 3 As shown, the heat dissipation mechanism 103 includes a heat dissipation element 2 , and the heat dissipation element 2 is connected to the electrode layer 102 of the electrode sheet 100 to form a heat exchange space 3 .

[0070] The heat exchange space 3 has an inlet 4 and an outlet 5 , and the inlet 4 and the outlet 5 are used for heat exchange medium to enter and exit the heat exchange space 3 . The heat exchange medium in the heat exchange space 3 exchanges heat with the electrode sheet 100 .

[0071] In some cases, the inlet 4 and the outlet 5 may be formed based on the connection method between the heat sink 2 and the electrode sheet 100, such as the connection between the heat sink 2 and the electrode sheet 100 is non-sealed, so that a channel is formed in the unsealed part to serve as the inlet 4 and / or the outlet 5. The heat sink 2 and the electrode sheet 100 are non-sealed, so that the heat exchange medium can flow in the channel formed by the unconnected parts of the heat sink 2 and the electrode sheet 100. When the heat exchange medium flows through the channel, it can exchange heat with the part of the electrode sheet 100 that forms the channel. In this way, the inlet 4 and / or the outlet 5 are provided, which is equivalent to increasing the heat dissipation area of ​​the electrode sheet 100.

[0072] In some other cases, the inlet 4 and / or the outlet 5 are directly formed on the heat sink 2 . Alternatively, in some other cases, the inlet 4 and / or the outlet 5 can also be directly formed on the electrode sheet 100 .

[0073] The heat sink 2 and the electrode sheet 100 are sealed and connected with each other. By setting the position of the inlet 4 and / or outlet 5 relative to the heat exchange space 3, the position of the inlet 4 and outlet 5 can be clearly determined, so that the flow path of the heat exchange medium can be preset. It is also convenient to set the size of the inlet 4 and outlet 5 to adjust the residence time of the heat exchange medium, thereby obtaining a better combination of flow path and flow rate, and achieving better heat dissipation effect and heat exchange efficiency.

[0074] Heat exchange medium refers to a substance used to transfer heat during heat exchange. The heat exchange medium in the embodiment of the present application is a fluid including liquid and gas, such as oil, solution, water, air, etc.

[0075] In some embodiments, the heat dissipation mechanism 103 includes a heat exchange medium source for providing a heat exchange medium.

[0076] For example, Figure 1 As shown, the heat exchange medium source includes a storage mechanism 201 and a power mechanism 202. The storage mechanism 201 is used to store the heat exchange medium, and the power mechanism 202 is used to drive the heat exchange medium to flow between the storage mechanism 201 and the heat exchange space.

[0077] For example, Figure 2 As shown, the heat exchange medium source includes an air dynamic pump 203, which is used to pass air into the heat dissipation mechanism 103 of the electrode sheet 100, using air as a heat exchange medium to remove heat by flowing air in the heat exchange space 3.

[0078] In some embodiments, the heat exchange medium source further includes a temperature regulating mechanism, which is disposed on the heat exchange medium delivery path and is used to regulate the temperature of the heat exchange medium according to the temperature of the electrode sheet 100 to achieve a better heat exchange effect. The temperature regulating mechanism is not shown in the figure, and it can be understood that the temperature regulating mechanism is a mechanism in the prior art that can cool or heat a substance, such as a small semiconductor refrigeration heater or compressor.

[0079] In some embodiments, Figure 4 As shown, the heat dissipation mechanism 103 also includes a substrate 1, which is arranged on the side of the heat sink 2 facing the electrode layer 102, and the heat sink 2 is connected to the electrode layer 102 through the substrate 1. The heat exchange space 3 is formed between the substrate 1 and the heat sink 2. In some embodiments, the heat exchange medium in the heat exchange space exchanges heat with the electrode layer 102 through the substrate 1 to reduce the heat generated by the operation of the electrode layer 102. Optionally, the substrate 1 and the heat sink 2 can also conduct heat to take away the heat generated by the electrode layer 102 through the heat exchange medium.

[0080] The substrate 1 is a structure for connecting the heat sink 2 and the electrode sheet 100 . It not only plays a connecting role, but also protects the electrode sheet 100 when it is bent and deformed, thereby further ensuring the stability of the connection between the heat sink 2 and the electrode sheet 100 .

[0081] The substrate 1 may be made of a variety of materials, and may be a glue layer, which is a conventional adhesive in the prior art.

[0082] In some embodiments, the substrate 1 includes a hollow area 11, and the hollow area 11 is used to expose the electrode sheet 100, that is, the surface of the electrode sheet 100 can be exposed in the hollow area 11, and the heat exchange medium in the heat exchange space 3 directly contacts the surface of the electrode sheet 100 from the hollow area 11 and performs heat exchange, thereby reducing the temperature of the electrode sheet 100 and solving the heat dissipation problem of the electrode sheet 100. The heat dissipation mechanism 103 provided in the embodiment of the present application has a simple structure, does not affect the fit of the electrode sheet 100 to the skin, and can improve the comfort of the treatment process.

[0083] like Figure 4 and Figure 5As shown, the substrate 1 also includes an edge region 12, which is surrounded by the hollow region 11. When the heat sink 2 is sealed and connected to the edge region 12, the hollow region 11 is covered. On the one hand, the connection and sealing between the substrate 1 and the heat sink 2 are ensured, and on the other hand, when the edge region 12 is attached to the electrode sheet 100, an annular sealing band is formed to prevent leakage of the heat exchange medium.

[0084] Optionally, the edge region 12 has enough area for the heat sink 2 to be connected, thereby ensuring the sealing performance.

[0085] In some embodiments, the substrate 1 and the heat sink 2 can also be configured to be integrally formed to achieve a sealed connection between the substrate 1 and the heat sink 2, and to allow the heat dissipation mechanism 103 to be formed independently of the electrode sheet 100, so that it can be applied to a variety of different electrode sheets 100, and to facilitate the maintenance and replacement of the heat dissipation mechanism 103 on the electrode sheet 100.

[0086] In some embodiments, the hollow area 11 is provided with a plurality of through holes 111. The "plurality" mentioned in the embodiments of the present application refers to two or more.

[0087] The through hole 111 has various shapes, and can be a circular hole (such as Figure 5 As shown), it can also be a strip hole (i.e. a through slot, such as Figure 6 As shown), it can also be other shapes, which are not listed here one by one.

[0088] In some embodiments, Figure 7 As shown, the hollow area 11 is a through hole 111 formed on the substrate 1, that is, the edge area 12 is annular, and the hollow area 11 is formed by surrounding the inner edge of the edge area 12. In the entire hollow area 11, the heat exchange medium can contact the electrode sheet 100 for heat exchange, and has a large heat exchange area.

[0089] The size of the through hole 111 is not limited, as long as the heat exchange medium and the electrode sheet 100 can be fully in contact with each other for heat exchange.

[0090] In some embodiments, multiple through holes 111 are evenly distributed throughout the hollow area 11 to make the electrode sheet 100 exchange heat evenly as much as possible. Since the electrode sheet 100 used for tumor electric field therapy is attached to the human body, the surface of the human body has curvature, undulations and is not flat, and the treatment process occurs in the entire life scene of the person, and human activities will also cause surface skin, so the electrode sheet 100 is easy to bend with the human body. By setting a plurality of evenly arranged through holes (micropores) in the hollow area 11, the non-through hole part of the hollow area 11 is also evenly arranged, and the stress of the hollow area 11 is relatively dispersed. During the bending process of the electrode sheet 100, the hollow area 11 is not prone to stress concentration problems, the substrate 1 is not easily damaged, and the structural strength of the entire heat dissipation mechanism 103 is relatively high.

[0091] like Figure 8 As shown, when the heat exchange medium enters between the non-through hole 111 part of the hollow area 11 and the electrode sheet 100, the substrate 1 may be subjected to a force in a direction away from the electrode sheet 100. Long-term use will cause the connection between the edge area 12 and the electrode sheet 100 to become loose and the seal to fail, which may easily cause the heat exchange medium to leak. In some embodiments, as Fig. 9 As shown, the hollow area 11 fits the electrode sheet 100 to prevent the heat exchange medium from entering between the non-through hole 111 part of the hollow area 11 and the electrode sheet 100, avoid tension on the edge area 12, and improve the connection stability between the substrate 1 and the electrode sheet 100.

[0092] The substrate 1 in the embodiment of the present application can be made of insulating material to avoid the substrate 1 and the electrode sheet 100 from contacting and conducting electricity, thereby preventing other unnecessary electrical hazards, such as leakage problems, and improving the safety of the heat exchange process. For example, the substrate 1 is made of an insulating, dense polymer material, such as polyimide or polyester film.

[0093] There are many ways to bond the substrate 1 to the electrode sheet 100. For example, the substrate 1 is made of a material with a certain degree of viscosity and is bonded to the electrode layer 102 using its own viscosity. In another example, the substrate 1 is wrapped around the electrode sheet 100 and tension is used to make the substrate 1 and the electrode sheet 100 fit tightly together. In another example, an adhesive is coated on the surface of the substrate 1 and the substrate 1 is bonded to the electrode sheet 100.

[0094] In some embodiments, Fig. 9 As shown, the substrate 1 includes an insulating layer and an adhesive layer, the insulating layer is connected to the electrode sheet 100 through the adhesive layer, and the hollowed-out portion of the hollowed-out region 11 (i.e., the through hole 111) penetrates from the insulating layer to the adhesive layer. By setting the substrate 1 to include an insulating layer and an adhesive layer, and setting the through hole 111 penetrating the insulating layer and the adhesive layer on the substrate 1 before pasting, on the one hand, the connection force between the substrate 1 and the electrode sheet 100 is ensured, and on the other hand, the through hole 111 (especially the micropore) set in the hollowed-out portion is prevented from being blocked by the adhesive, so as to ensure that the heat exchange medium can contact and exchange heat with the electrode sheet 100 through the hollowed-out portion.

[0095] like Fig. 9 As shown, the heat sink 2 includes a connecting portion 21 and a covering portion 22. The connecting portion 21 is arranged around the covering portion 22. The connecting portion 21 is used to be sealed and connected to the edge area 12. The covering portion 22 covers the hollow area 11. A heat exchange space 3 is formed between the covering portion 22 and the hollow area 11, and an annular sealing belt is formed between the connecting portion 21 and the edge area 12 to prevent leakage of the heat exchange medium in the heat exchange space 3.

[0096] In some embodiments, the surface area of ​​the covering portion 22 is set to be larger than the surface area of ​​the hollow area 11, so that the covering portion 22 can bulge relative to the hollow area 11, thereby having a larger volume of heat exchange space 3 to ensure that there is a sufficient amount of heat exchange medium to fully exchange heat with the electrode sheet 100.

[0097] Optionally, the covering portion 22 is made of a flexible material, and the heat exchange medium can easily pass through the covering portion 22 and the non-hollow portion of the hollow area 11, thereby filling the entire heat exchange space 3 and flowing in the heat exchange space 3, and the covering portion 22 can easily bulge under the extrusion of the heat exchange medium to form an expanded heat exchange space 3.

[0098] Optionally, the covering portion 22 is made of an elastic material so that after the heat exchange medium enters the heat exchange space 3, the surface area of ​​the covering portion 22 is larger than the surface area of ​​the hollow area 11. Fig.10 As shown, when not in use, the cover 22 is flat against the hollow area 11, and is not easily scratched by hooks or damaged by pulling. In addition, the cover 22 does not take up extra space, and the overall volume of the electrode sheet 100 is small, which is convenient for storage. Fig. 9 As shown, when in use, the heat exchange medium squeezes the cover part 22, overcomes the elastic force of the cover part 22 to make it arch, thereby increasing the heat exchange space 3, increasing the total amount of heat exchange medium in the heat exchange space 3, increasing the amount of heat that can be absorbed, and reducing the temperature rise of the heat exchange medium, so that the temperature difference between the heat exchange medium and the electrode sheet 100 is large, and the heat exchange efficiency is high. Then, through the flow of the heat exchange medium, the heat exchange medium with a lower temperature is continuously replaced, so as to achieve fast and efficient heat exchange.

[0099] The material of the connection portion 21 can be the same as that of the covering portion 22 , and the connection portion 21 and the covering portion 22 are integrally formed.

[0100] The material of the connection part 21 may also be different from that of the covering part 22. For example, the connection part 21 is made of a material that is not easy to deform, and the connection part 21 is not easy to deform and cause leakage problems after being connected to the base 1. In some embodiments, the connection part 21 and the covering part 22 can be integrally formed with a flexible or elastic material, and the heat dissipation mechanism 103 also includes a hard ring body, which is connected to the base 1, and the connection part 21 is pressed against the base 1 through the hard ring body, so that the connection part 21 and the base 1 are sealed. Optionally, the hard ring body has an annular surface facing the base 1, and a plurality of concentric annular protrusions are provided on the annular surface, so that the connection part 21 is further squeezed by the plurality of annular protrusions to form a plurality of annular sealing belts to improve the sealing performance.

[0101] like Fig. 9As shown, the inlet 4 and the outlet 5 are arranged on the covering part 22. The inlet 4 and the outlet 5 are structures for the heat exchange medium to enter and exit. Compared with setting the inlet 4 and the outlet 5 on the connecting part 21, on the one hand, it can prevent the heat sink 2 from being loosened and the seal from failing; on the other hand, Fig. 9 As shown, the inlet 4 and the outlet 5 are opposite to the hollow area 11. After the new heat exchange medium enters the heat exchange space 3, it flows toward the electrode sheet 100, squeezing the original heat exchange medium in the direction away from the electrode sheet 100, so that the heat exchange medium after absorbing heat continues to move away from the electrode sheet 100 and flows out of the heat exchange space 3, and new heat exchange medium with a lower temperature continuously contacts the electrode sheet 100, forming an efficient heat exchange flow path.

[0102] In some embodiments, the inlet 4 is arranged in the middle of the cover 22, and the outlet 5 is closer to the edge of the cover 22 than the inlet 4. The middle of the electrode sheet 100 is more difficult to dissipate heat than the edge. By arranging the inlet 4 in the middle of the cover 22, the new heat exchange medium first flows toward the center of the electrode sheet 100 after entering the heat exchange space 3, which is conducive to accelerating the heat dissipation of the middle of the electrode sheet 100. The outlet 5 arranged closer to the edge of the cover 22 cooperates with the inlet 4 to guide the heat exchange medium to flow from the middle to the edge and then flow out in a direction away from the electrode sheet 100, ensuring that the edge of the electrode sheet 100 is also fully cooled.

[0103] The present application does not limit the number of inlets 4 and outlets 5, as long as sufficient flow and renewal of the heat exchange medium can be ensured.

[0104] In some embodiments, Fig.12 As shown, the heat dissipation mechanism 103 also includes a connecting pipe 6 and an elastic sleeve 7. The connecting pipe 6 is arranged between the heat exchange medium source and the inlet 4, and is used to connect the heat exchange medium source and the inlet 4. The elastic sleeve 7 is sleeved on the outside of the connecting pipe 6, and is used to seal the gap between the connecting pipe 6 and the inlet 4. The outer peripheral surface of the elastic sleeve 7 is a conical surface, so as to guide the connecting pipe 6 to enter the inlet 4. After the connecting pipe 6 is inserted into the inlet 4, the elastic sleeve 7 is elastically squeezed, and the elastic sleeve 7 is kept against the inner wall of the inlet 4 to seal the gap between the connecting pipe 6 and the inlet 4.

[0105] Optionally, the inlet 4 includes a first connecting section and a second connecting section that are connected. The first connecting section has a large inlet and a small outlet, which serves to guide the connecting pipe 6 to enter. The inner wall of the first connecting section is a slope to guide the connecting pipe 6 to be centrally inserted into the second connecting section, thereby avoiding the connecting pipe 6 from being bent and folded, and avoiding the inner wall of the first connecting section from causing obstruction between the connecting pipe 6 and the second connecting section, thereby ensuring that a smooth flow channel is formed between the internal space of the connecting pipe 6 and the second connecting section.

[0106] Optionally, the other end of the connecting tube 6 for connecting the inlet 4 is configured as a flat tube. After the flat tube enters the first connecting section, it is gradually deformed under the extrusion of the inner wall of the first connecting section and plugged into the second connecting section. Through the extrusion and shaping effect of the first connecting section, the inner circumference of the flat tube fits the inner wall of the inlet 4, which is conducive to the clamping of the flat tube and the inlet 4 and improves the connection stability.

[0107] According to this application Figure 1 , Figure 2 , Figure 4-Figure 10 As shown, the embodiment of the present application provides a heat dissipation mechanism 103 of an electrode sheet 100, an electrode sheet 100 having a heat dissipation mechanism 103, and a treatment system 1000 for electric field therapy of tumors having the electrode sheet 100. The treatment system 1000 includes at least one pair of electrode sheets 100 and a generator for generating an electric field for tumor treatment. The electrode sheet 100 includes a dielectric layer 101, an electrode layer 102, and a heat dissipation mechanism 103. The dielectric layer 101 is used to be attached to the skin, the electrode layer 102 is located on the side of the dielectric layer 101 away from the skin, and the heat dissipation mechanism 103 is arranged on the electrode layer 102. The heat dissipation mechanism 103 includes a substrate 1 and a heat sink 2. The substrate 1 is attached to the surface of the electrode layer 102. The substrate 1 includes a hollow area 11 and an edge area 12. The edge area 12 is surrounded by the hollow area 11. The heat sink 2 includes a connecting portion 21 and a covering portion 22. The connecting portion 21 is arranged around the covering portion 22. The connecting portion 21 is sealed and connected to the edge area 12, so that a sealed heat exchange space 3 is formed between the substrate 1 and the heat sink 2. The covering portion 22 is made of a flexible material. An inlet 4 is arranged in the middle of the covering portion 22. The heat exchange medium enters from the middle of the covering portion 22 and first exchanges heat with the center of the electrode sheet 100. A plurality of outlets 5 are evenly arranged on the edge of the covering portion 22 to guide the heat exchange medium to flow to the edge to dissipate heat from the edge of the electrode sheet 100. By setting the flow area of ​​the outlet 5 and the inlet 4, and by squeezing the covering portion 22 from the inside to the outside when the heat exchange medium flows, the covering portion 22 is raised to expand the heat exchange space 3, accommodate more heat exchange medium, and enable the heat exchange medium to flow fully to achieve uniform heat exchange. The heat exchange medium source of the treatment system 1000 is an air pump 203, the output pipe of the air pump 203 is connected to the inlet 4 of the cover 22, and air is passed into the heat exchange space 3, and the air is used as the heat exchange medium to dissipate the heat of the electrode sheet 100. After the air and the electrode sheet 100 exchange heat, the air is discharged to the external environment through the outlet 5. The heat dissipation mechanism 103 for the electrode sheet 100 provided in the embodiment of the present application has a simple structure, can accelerate the heat dissipation of the electrode sheet 100, make the electrode sheet 100 have a better skin feel, and improve the comfort of the treatment process.

[0108] It should be noted that the electrode sheet 100 provided in the embodiment of the present application includes but is not limited to a dielectric layer 101 and an electrode layer 102 located on one side of the dielectric layer 101. Fig.11As shown, an electrode layer 102 may also be provided on the other side of the dielectric layer 101 , and attached to the human skin through the electrode layer 102 .

[0109] The above description is only the preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A heat dissipation mechanism for an electrode sheet, characterized in that: include: The heat sink is connected with the electrode sheet to form a heat exchange space, wherein the heat exchange space has an inlet and an outlet for the heat exchange medium to flow through, so that the heat exchange medium in the heat exchange space can exchange heat with the electrode sheet.

2. The heat dissipation mechanism according to claim 1, characterized in that: The heat dissipation mechanism also includes: The substrate is arranged on a side of the heat sink facing the electrode sheet. The heat sink is connected to the electrode sheet through the substrate. The heat exchange space is formed between the substrate and the heat sink.

3. The heat dissipation mechanism according to claim 2, characterized in that: The substrate includes a hollow area, and the hollow area is used to expose the electrode sheet to the heat exchange space.

4. The heat dissipation mechanism according to claim 3, characterized in that: The hollow area is provided with a plurality of through holes or through grooves, and the plurality of through holes or through grooves are distributed in the hollow area.

5. The heat dissipation mechanism according to claim 3, characterized in that: The substrate further includes an edge region, which is surrounded by the hollow region, and the edge region is sealed and connected to the electrode sheet and the heat sink.

6. The heat dissipation mechanism according to claim 5, characterized in that: The heat sink includes a connecting portion and a covering portion, wherein the connecting portion is connected to the edge region, and the heat exchange space is formed between the covering portion and the hollow region.

7. The heat dissipation mechanism according to claim 6, characterized in that: In the heat sink, at least the covering portion is made of a flexible material or an elastic material.

8. The heat dissipation mechanism according to claim 6, characterized in that: The inlet and the outlet are provided at the cover portion.

9. The heat dissipation mechanism according to claim 8, characterized in that: The inlet is disposed in the middle of the cover portion.

10. The heat dissipation mechanism according to claim 9, characterized in that: The outlet is closer to the edge of the covering portion than the inlet.

11. The heat dissipation mechanism according to claim 3, characterized in that: The substrate includes an insulating layer and an adhesive layer, the insulating layer is connected to the electrode sheet through the adhesive layer, and the hollowed-out portion of the hollowed-out area penetrates from the insulating layer to the electrode sheet.

12. The heat dissipation mechanism according to claim 1, characterized in that: The heat dissipation mechanism also includes: A heat exchange medium source is used to introduce heat exchange medium into the heat exchange space.

13. An electrode sheet for electric field therapy of tumors, characterized in that: include: Dielectric layer; An electrode layer, disposed on one side of the dielectric layer; The heat dissipation mechanism according to any one of claims 1 to 12, wherein the heat dissipation mechanism is connected to the electrode layer.

14. A therapeutic system for electric field therapy of tumors, characterized in that: include: At least one pair of electrode sheets as claimed in claim 13; and A generator that produces tumor treating electric fields.

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