Tumor electric field treatment system, electrode plate and method

Abstract

The invention provides a tumor electric field treatment system, electrode plates and a method, the system comprises at least one pair of electrode plates, each electrode plate comprises a plurality of electrode units and a plurality of temperature detection units, and each temperature detection unit is arranged corresponding to one electrode unit; the plurality of electrode units of each electrode plate are configured into a plurality of row groups and a plurality of column groups in circuit connection, and the electrode units in each row group are connected in parallel; the temperature detection units in each row group are connected in series, the temperature detection units in each column group are jointly connected to a grounding pin through a control switch, the electrode units in each row group are connected in parallel, and the temperature detection units in each row group are jointly connected to a bidirectional switching unit through a dual-purpose signal line after being connected in series. Under the condition that the dual-purpose signal line is communicated to the temperature sampling point, the on-off state of the control switch is configured to enable analog temperature signals detected by the temperature sensors corresponding to one or more combinations to be sampled based on the temperature sampling point; under the condition that the dual-purpose signal line is communicated with the alternating power line, the electrode units of each row group are applied with alternating electric signals based on the alternating power line. As such, the plurality of electrode units are zoned controlled using fewer conductive traces.

Description

Technical Field

[0001] The present application relates to tumor electric field therapy technology, and in particular to a tumor electric field therapy system, electrode sheet and method. Background Art

[0002] Tumor electric field therapy is a method that uses low-intensity, medium-to-high-frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, inhibit the separation of intracellular organelles during cell division, and induce apoptosis of cells during mitosis, thereby achieving the effect of treating tumors.

[0003] Compared with traditional cancer treatments, tumor electric field therapy has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometric shape and high-frequency mitosis, make them susceptible to tumor electric field therapy. Tumor electric field therapy disrupts the normal aggregation of tubulin by exerting directional forces on polar particles (such as macromolecules and organelles) within cells. These processes may lead to physical damage to the cell membrane and cell apoptosis. At the end of cell mitosis, the structural morphology of the cleavage furrow will lead to uneven distribution of the electric field around it. At the same time, under the influence of tumor electric field therapy, the electric field intensity at the cleavage furrow is significantly enhanced, and the charged substances in the cell move toward the cleavage furrow, which interferes with or even destroys the formation of the cell structure, and ultimately leads to cell division failure and apoptosis.

[0004] The tumor electric field therapy system in the related art uses an electric field application device to transmit the alternating electric signal for tumor electric field therapy to the electrode sheet, and then applies the alternating electric field to the patient's tumor site through the electrode sheet for tumor electric field therapy. When the tumor treatment electric field is applied to the patient's body, heat will accumulate at the application site, and the temperature will rise accordingly. Therefore, it is necessary to monitor the temperature of the application site. When the temperature is too high, the electric field strength needs to be adjusted in time to reduce the risk of skin burns caused by excessive temperature.

[0005] The tumor electric field therapy system includes at least one pair of electrode sheets, each of which has multiple electrode units. Even if the same alternating electrical signal is applied to each electrode unit, the heat generated by each electrode unit will be different due to its different position, that is, the temperature of each electrode unit on the entire electrode sheet will not be completely consistent. In this way, it is possible that the temperature of some electrode units in the entire electrode sheet exceeds the preset temperature, while the temperature of other electrode units is normal. In order to improve the effect of tumor electric field therapy, it is necessary to implement individual control on the over-temperature electrode units. However, for the electrode sheets in the related art, the individual control of the electrode units requires a conductive trace to be set for each electrode unit in the substrate of the electrode sheet, which will increase the number of conductive traces in the electrode sheet substrate so that the electrode sheet is not easy to bend, and the cable electrically connected to the electrode sheet will also be thickened, which increases the overall weight of the electrode sheet, which is not conducive to the application of the electrode sheet. Summary of the invention

[0006] The present application aims to solve at least one of the technical problems in the related art to a certain extent. To this end, the first purpose of the present application is to propose a tumor electric field therapy system, which can control multiple electrode units by partitioning using fewer conductive traces, which can not only improve the effect of tumor electric field therapy, but also facilitate the application of electrode sheets.

[0007] The second objective of the present application is to provide an electrode sheet.

[0008] The third objective of the present application is to provide a method for detecting the temperature of an electrode sheet.

[0009] The fourth objective of the present application is to provide a method for detecting the quality of an electrode sheet.

[0010] The fifth objective of the present application is to provide a quality detection system for an electrode sheet.

[0011] To achieve the above-mentioned purpose, the first aspect of the present application provides a tumor electric field treatment system, comprising: at least one pair of electrode sheets, each of which includes a plurality of electrode units and a plurality of temperature detection units, each of which can apply an alternating electric signal, and each of which is set corresponding to an electrode unit to detect the temperature at the corresponding electrode unit; wherein the plurality of electrode units are configured as a plurality of row groups and a plurality of column groups in circuit connection, and the electrode units in each row group are connected in parallel to simultaneously apply an alternating electric signal to the electrode units connected in parallel in each row group; the temperature detection units in each row group are connected in series; and the temperature detection units in each column group are connected together through a control switch. to the ground pin; and after the electrode units in each row group are connected in parallel and the temperature detection units in each row group are connected in series; they are connected to a bidirectional switching unit through a dual-purpose signal line; the bidirectional switching unit is configured to switch the dual-purpose signal line to connect to a temperature sampling point or an alternating power line, wherein, when the dual-purpose signal line is connected to the temperature sampling point, the switching state of the control switch is configured so that the analog temperature signal detected by the temperature detection unit corresponding to one or more combinations is sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, the electrode unit of at least one row group is applied with the alternating electrical signal based on the alternating power line.

[0012] According to the tumor electric field therapy system of the embodiment of the present application, for each electrode sheet, multiple electrode units are divided into multiple row groups and multiple column groups in terms of circuit connection, and the ground ends of the temperature detection units corresponding to the electrode units in each column group are commonly connected to the ground pin through a control switch, the electrode units in each row group are connected in parallel, so that an alternating electric signal is simultaneously applied to the electrode units in each row group after being connected in parallel, the temperature detection units in each row group are connected in series, and the electrode units in each row group are connected in parallel and in series and then connected to a bidirectional switching unit through a dual-purpose signal line; at the same time, a bidirectional switching unit is provided to switch the dual-purpose signal line to connect to a temperature sampling point or an alternating power line, so that when the dual-purpose signal line is connected to the temperature sampling point, the switching state of the control switch is configured so that the analog temperature signals detected by the temperature detection units corresponding to one or more combinations are sampled based on the temperature sampling point, and when the dual-purpose signal line is connected to the alternating power line, an alternating electric signal is applied to the electrode units of each row group based on the alternating power line. In this way, temperature sampling and application of alternating electric signals can be achieved through the dual-purpose signal line. Not only is no new AC signal line (i.e., AC line) added, but the original AC signal line is also eliminated, so that multiple electrode units can be partitioned and controlled using fewer conductive traces. The partition control includes applying alternating electric signals to the electrode units of each row group respectively, and collecting the analog temperature signals detected by the temperature detection units corresponding to one or more combinations in each row group respectively. This not only can achieve accurate and comprehensive detection of the temperatures of all electrode units, but also is conducive to the application of electrode sheets.

[0013] Furthermore, each of the electrode sheets also includes a plurality of rectifier switching modules, each of the rectifier switching modules corresponds to one of the plurality of row groups of the electrode units, each of the temperature detection units in each of the row groups is connected in series and then connected to the first end of the corresponding rectifier switching module; each of the electrode units in each of the row groups is connected in parallel and then connected to the second end of the corresponding rectifier switching module; and the third end of the rectifier switching module corresponding to each of the row groups is connected to the dual-purpose signal line corresponding to each of the row groups.

[0014] Furthermore, the bidirectional switching unit includes a plurality of bidirectional switching switches corresponding one-to-one to the plurality of row groups of the electrode units, wherein the first end of each of the bidirectional switching switches is connected to the temperature sampling point of the corresponding row group; the second end of each of the bidirectional switching switches is simultaneously connected to the alternating power line; and the third end of each of the bidirectional switching switches is connected to the dual-purpose signal line corresponding to the corresponding row group.

[0015] Furthermore, each of the rectifier switching modules includes an electromagnetic control switch, and the electromagnetic control switch corresponding to each row group is linked to the bidirectional switching switch corresponding to the row group; wherein, when the bidirectional switching switch corresponding to each row group is switched to a state where its third end is connected to its first end, the electromagnetic control switch corresponding to the row group follows the switch to a state where the third end of the corresponding rectifier switching module is connected to its first end, so that according to the switch state of the control switch, the analog temperature signals detected by the temperature detection units corresponding to one or more combinations are sampled respectively; when the bidirectional switching switch corresponding to each row group is switched to a state where its third end is connected to its second end, the electromagnetic control switch corresponding to the row group follows the switch to a state where the third end of the corresponding rectifier switching module is connected to its second end, so that the electrode units of each row group are simultaneously applied with the alternating electrical signal based on the alternating power line.

[0016] Furthermore, each of the rectifier switching modules also includes a rectifier bridge and a voltage regulator tube. The first end of the rectifier bridge is connected to the dual-purpose signal line corresponding to the corresponding row group electrode unit and the third end of the electromagnetic control switch. A voltage regulator tube is connected in series between the second end of the rectifier bridge and the fourth end of the rectifier bridge. The third end of the rectifier bridge is connected to the ground pin. The anode of the voltage regulator tube is connected to the fourth end of the rectifier bridge, and the cathode of the voltage regulator tube is connected to the second end of the rectifier bridge. Each of the electromagnetic control switches includes a first end, a second end and a third end. The first end of the electromagnetic control switch constitutes the first end of the rectifier switching module, the second end of the electromagnetic control switch constitutes the second end of the rectifier switching module, and the third end of the electromagnetic control switch is connected to the first end of the rectifier bridge to constitute the third end of the rectifier switching module.

[0017] Furthermore, each of the temperature detection units also includes a temperature sensor and a diode connected in series with the temperature sensor, the anode of each of the diodes is connected to the ground terminal of the corresponding temperature sensor, and the cathodes of the diodes corresponding to each of the column groups are connected together and then connected to the ground pin through the corresponding control switch.

[0018] Furthermore, each of the temperature sampling points is connected to a DC power supply via a corresponding voltage-dividing resistor.

[0019] Furthermore, it also includes an adapter, wherein the control switch, the bidirectional switching unit and the voltage dividing resistor are respectively arranged in the adapter.

[0020] Furthermore, the adapter includes a first controller and an ADC unit, the ADC unit is connected to each of the temperature sampling points to sample the analog temperature signal through each of the temperature sampling points, and the first controller is connected to the ADC unit to determine the temperature at the corresponding electrode unit based on the digital temperature signal output by the ADC unit.

[0021] Furthermore, the first controller is also configured to configure the switch state of the control switch.

[0022] Furthermore, the first controller is also configured to configure the switching state of the bidirectional switch in the bidirectional switching unit.

[0023] Furthermore, it also includes an electric field generator, which is configured to output the alternating electric signal through the alternating power line.

[0024] Furthermore, the electric field generator includes a second controller and an AC signal generator, the second controller is connected to the AC signal generator, and the second controller is configured to control the AC signal generator to adjust the strength of the alternating electric signal output by the alternating power line.

[0025] Furthermore, the electric field generator is also configured to obtain the temperature at each electrode unit and control the AC signal generator according to the temperature at each electrode unit.

[0026] Furthermore, the electric field generator also includes a power switch, which is arranged between the AC signal generator and the bidirectional switching unit. Under the configuration of the second controller, the power switch controls whether the AC signal generator outputs the alternating electric signal through the alternating power line.

[0027] Furthermore, the second controller is also configured to configure the switch state of the control switch.

[0028] Furthermore, the second controller is also configured to configure the switching state of the bidirectional switch in the bidirectional switching unit.

[0029] To achieve the above-mentioned purpose, the second embodiment of the present application provides an electrode sheet for use in a tumor electric field therapy system, the tumor electric field therapy system including a bidirectional switching unit, the electrode sheet including: a substrate; a plurality of electrode units and a plurality of temperature detection units arranged on the substrate, each of the electrode units being capable of applying an alternating electric signal, each of the temperature detection units corresponding to an electrode unit being arranged to detect the temperature at the corresponding electrode unit; wherein the plurality of electrode units are configured as a plurality of row groups and a plurality of column groups in terms of circuit connection, the electrode units in each row group being connected in parallel to simultaneously apply an alternating electric signal to the electrode units connected in parallel in each row group; and each temperature detection unit in each row group being configured as a plurality of row groups and a plurality of column groups in terms of circuit connection. The units are connected in series; the temperature detection units in each of the column groups are connected to the ground pin through a control switch; and the electrode units in each row group are connected in parallel and the temperature detection units in each of the row groups are connected in series and then connected to the bidirectional switching unit through a dual-purpose signal line; when the dual-purpose signal line is connected to the temperature sampling point, the switching state of the control switch is configured so that the analog temperature signal detected by the temperature detection unit corresponding to one or more combinations is sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, the alternating electrical signal is applied to the electrode unit of at least one of the row groups based on the alternating power line.

[0030] To achieve the above-mentioned purpose, the third aspect of the present application provides an electrode sheet temperature detection method, which is applied to the aforementioned tumor electric field therapy system, and the method includes: controlling the bidirectional switching unit so that the dual-purpose signal line corresponding to any one of the row groups in the corresponding electrode sheet is connected to the corresponding temperature sampling point; controlling the control switch corresponding to each of the column groups so as to sample the analog temperature signal of the corresponding electrode unit based on the corresponding temperature sampling point.

[0031] To achieve the above-mentioned purpose, the fourth aspect of the present application provides an electrode sheet quality detection method, which is applied to the electrode sheet quality detection system, wherein the electrode sheet quality detection system includes the aforementioned tumor electric field therapy system and a host computer, and the host computer and the tumor electric field therapy system are communicatively connected, and the method includes: obtaining the analog temperature signal detected by each temperature detection unit in the electrode sheet; determining the state of each temperature detection unit according to the analog temperature signal detected by each temperature detection unit, and assigning a corresponding code to determine the test code array of the electrode sheet; comparing the test code array with the standard code array for consistency to determine whether the electrode sheet is qualified, wherein the standard code includes at least the first code of a first code and a second code, the first code is used to indicate that the temperature detection unit is in a normal state, and the second code is used to indicate that the temperature detection unit is in an open circuit state or an unset state.

[0032] Furthermore, the test code array includes at least one of a first code, a second code and a third code, and the third code is used to indicate that the temperature detection unit is in a short-circuit state.

[0033] Furthermore, the analog temperature signal is characterized by a voltage value, and a test code array of the electrode sheet is determined according to the analog temperature signal detected by each temperature detection unit, including: determining a voltage range in which the voltage value is located; determining a code corresponding to the corresponding temperature detection unit according to the voltage range in which the voltage value is located, wherein different voltage ranges correspond to different codes; and generating a test code array of the corresponding electrode sheet according to the code corresponding to each temperature detection unit.

[0034] Furthermore, before comparing the test coding array with the standard coding array, the method also includes: when a qualified electrode sheet is connected to the adapter of the tumor electric field therapy system, controlling the adapter to work, and determining the standard coding array based on the analog temperature signal currently detected by each of the temperature detection units.

[0035] To achieve the above-mentioned purpose, the fifth aspect of the present application provides an electrode sheet quality detection system, including a tumor electric field therapy system, a host computer, an alarm and a display, the host computer and the tumor electric field therapy system are communicatively connected, the alarm and the host computer are communicatively connected, the display and the host computer are communicatively connected, and the electrode sheet quality detection system is used to execute the aforementioned electrode sheet quality detection method.

[0036] The above description is only an overview of the technical solution of the present application. In order to more clearly understand the technical means of the present application, it can be implemented in accordance with the contents of the specification. In order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] Figure 1 A schematic block diagram of a tumor electric field treatment system according to an embodiment of the present application;

[0038] Figure 2 A schematic block diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0039] Figure 3 for Figure 1 or Figure 2 A schematic diagram of a partition structure of an electrode sheet of a tumor electric field treatment system shown in FIG.

[0040] Figure 4 for Figure 1 or Figure 2A schematic diagram of a circuit connection between an electrode sheet and an adapter of the tumor electric field treatment system shown in FIG.

[0041] Figure 5 A schematic structural diagram of an embodiment of an electrode unit of an electrode sheet of a tumor electric field treatment system of the present application;

[0042] Figure 6 for Figure 1 or Figure 2 A schematic diagram of a circuit connection between an electrode sheet, an adapter, and an electric field generator of a tumor electric field treatment system shown in FIG.

[0043] Figure 7 for Figure 1 or Figure 2 A schematic block diagram of the internal structure of the adapter of the tumor electric field treatment system shown in ;

[0044] Figure 8 for Figure 1 or Figure 2 A schematic block diagram of the internal structure of the electric field generator of the tumor electric field treatment system shown in ;

[0045] Fig. 9 An electrode sheet of a tumor electric field treatment system according to another embodiment of the present application and Figure 1 or Figure 2 The circuit connection diagram of the adapter shown in ;

[0046] Fig.10 A schematic block diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0047] Fig.11 A schematic block diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0048] Fig.12 A schematic block diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0049] Fig.13 for Fig.10 or Fig.11 or Fig.12 A schematic diagram of a circuit connection between an electrode sheet and an adapter of the tumor electric field treatment system shown in FIG.

[0050] Fig.14 for Fig.13 A schematic block diagram of the internal structure of the adapter shown;

[0051] Fig.15 for Fig.10 or Fig.11 or Fig.12 A schematic diagram of another circuit connection between an electrode sheet of the tumor electric field treatment system and an adapter shown in FIG.

[0052] Fig.16 and Fig.15 Similar to Fig.10 or Fig.11 or Fig.12 A schematic diagram of another circuit connection between an electrode sheet of the tumor electric field treatment system and an adapter shown in FIG.

[0053] Fig.17 for Fig.15 or Fig.16 A schematic block diagram of the internal structure of the adapter shown in ;

[0054] Fig.18 An electrode sheet of a tumor electric field treatment system according to another embodiment of the present application and Fig.13 or Fig.14 The circuit connection diagram of the adapter shown in ;

[0055] Fig.19 A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0056] Fig. 20 for Fig.19 A schematic block diagram of the internal structure of the adapter shown in ;

[0057] Fig.21 A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0058] Fig. 22 for Fig.21 A schematic block diagram of the internal structure of the adapter shown in ;

[0059] Fig.23 A schematic block diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0060] Fig.24 for Fig.23 A schematic diagram of a circuit connection between an electrode sheet and an adapter of the tumor electric field treatment system shown in FIG.

[0061] Fig.25 and Fig.24 Similar, also Fig.23 A schematic diagram of another circuit connection between an electrode sheet of the tumor electric field treatment system and an adapter shown in FIG.

[0062] Fig.26 for Fig.25 A schematic block diagram of the internal structure of the adapter shown in ;

[0063] Fig. 27 A schematic diagram of a flow chart of an electrode sheet temperature detection method according to an embodiment of the present application;

[0064] Fig.28 Schematic diagram of the process of an electrode sheet qualification detection method according to an embodiment of the present application. DETAILED DESCRIPTION

[0065] The following embodiments of the technical solution of the present application are described in detail in conjunction with the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present application, and are therefore only used as examples, and cannot be used to limit the scope of protection of the present application.

[0066] Figure 1 FIG. 1 is a schematic diagram of a tumor electric field treatment system 100 according to an embodiment of the present application. Figure 1 As shown, the tumor electric field treatment system 100 includes: at least one pair of electrode sheets 13, an adapter 20 connected to the at least one pair of electrode sheets 13, and an electric field generator 30 connected to the adapter 20. The at least one pair of electrode sheets 13 can be arranged in pairs on the patient's body surface, such as Figure 1 There are four electrode sheets 13, and every two electrode sheets 13 are arranged as a pair on the patient's body surface. The electric field generator 30 is used to supply power to at least one pair of electrode sheets 13, so that at least one pair of electrode sheets 13 generates an alternating electric field for treating tumors. The adapter 20 is electrically connected between at least one pair of electrode sheets 13 and the electric field generator 30, and is used to transmit the alternating electric signal generated by the electric field generator 30 to at least one pair of electrode sheets 13. In other words, the electric field generator 30 is capable of generating an alternating electric signal, and the alternating electric signal generated by the electric field generator 30 is transmitted to each electrode sheet 13 through the adapter 20, so that an alternating electric field for treating tumors is generated between the same pair of electrode sheets 13, so as to apply an alternating electric field to the tumor site of the patient for tumor treatment.

[0067] like Figure 1 As shown, in this embodiment, the number of electrode sheets 13 is 4, each electrode sheet 13 includes a plurality of electrode units 33 of the same number, each electrode unit 33 is electrically connected to the adapter 20, and the number of electrode units 33 on each electrode sheet 13 is 20. In other embodiments, the tumor electric field treatment system 100 may also have more or fewer electrode sheets 13; in other embodiments, each pair of electrode sheets 13 has the same number of electrode units 33, and different pairs of electrode sheets 13 may have different numbers of electrode units 33; in other embodiments, the number of electrode units 33 on each electrode sheet 13 may be 9, 12, 13, 19, etc.

[0068] In this embodiment, the connection line between two electrode units 33 can be called a connecting strip, and the interval between the electrode units 33 can be adjusted by the connecting strip. If one electrode unit 33 is connected to another electrode unit 33 only by one connecting strip, the electrode unit 33 is an electrode unit 33 at a free end, for example Figure 1Each electrode sheet 13 shown has 9 electrode units 33 at free ends. The surrounding space where the electrode units 33 at the free ends are located is an open space, that is, the electrode units 33 at the free ends have a certain degree of freedom and can move freely in the open space. For example, the connecting belt can be stretched or bent to a certain extent, so that the electrode units 33 can move in all directions. The reason why some electrode units 33 are set in the form of free ends in this embodiment is that after the electrode sheet is attached to the human body, the electric fields of the electrode units 33 are inconsistent due to the wrinkles of the human skin and the corresponding impedance changes, which leads to inconsistent temperatures of the electrode units 33, and the electrode units 33 located at the periphery of the electrode sheet 13 heat faster. Therefore, when some electrode units 33 in the electrode sheet 13 are at the free ends, the electrode units 33 at the free ends can be adjusted to increase the heat dissipation space of the electrode units 33 at the periphery, thereby accelerating the heat dissipation. In addition, the attachment position of the electrode units 33 at the free ends on the human body can be adjusted to achieve the flexible attachment of the electrode units 33 at the free ends to the human body according to actual needs.

[0069] Figure 2 FIG. 1 is a schematic diagram of a tumor electric field treatment system 100 ′ according to another embodiment of the present application. Figure 2 As shown, its main concept and Figure 1 The tumor treating field system 100 shown is the same as that shown, except that: Figure 2 The connection method of the electrode units 33' in the electrode sheet 13' of the tumor electric field therapy system 100' shown is different. The connection method of the 10 electrode units 33' on the left side of the electrode sheet 13' is symmetrical to the connection method of the 10 electrode units 33' on the right side. The 10 electrode units 33' on the left side of the electrode sheet 13' have 4 electrode units 33' at the free ends, and the 10 electrode units 33' on the right side of the electrode sheet 13' have 4 electrode units 33' at the free ends.

[0070] Figure 4 for Figure 1 or Figure 2 The circuit connection diagram of the electrode sheet 13 and the adapter 20 of the tumor electric field treatment system 100 is shown. Figure 5 Schematic diagram of the structure of the electrode unit 33 is shown. It is worth noting that: Figure 4 The arrangement of the electrode units 33 shown is to more clearly illustrate the electrical connection between an electrode sheet 13 and the adapter 20. Figure 4 The arrangement of the electrode units 33 shown does not represent the arrangement of the electrode units 33 in the spatial structure. Figure 4As shown, a plurality of electrode units 33 in an electrode sheet 13 are configured into a plurality of row groups and a plurality of column groups, and a rectifier switching module 16 having a first end, a second end and a third end is provided corresponding to each row group, the first end of the rectifier switching module 16 is connected to each temperature detection unit 35 connected in series in the corresponding row group, the second end of the rectifier switching module 16 is respectively connected to each electrode unit 33 in the corresponding row group, and the third end of the rectifier switching module 16 is connected to the corresponding bidirectional switching switch 55 via a dual-purpose signal line 19. The third end of the rectifying switching module 16 can be electrically connected to its first end, so that the dual-purpose signal line 19 electrically connected to it is electrically connected to each temperature detection unit 34 connected in series in the corresponding row group, and then the temperature detection signal obtained by the combination of each electrode unit 34 in the corresponding row group can be collected through the dual-purpose signal line 19; the third end of the rectifying switching module 16 can also be electrically connected to its second end, so that the dual-purpose signal line 19 electrically connected to it is electrically connected to each electrode unit 33 connected in parallel in the corresponding row group, and then the alternating current signal is transmitted to each electrode unit 33 in the corresponding row group through the dual-purpose signal line 19. The third end of the rectifier switching module 16 can be switched between being connected to the first end and the second end in a cycle, so that the dual-purpose signal line 19 electrically connected thereto can be switched between being electrically connected to each series-connected temperature detection unit 34 of the corresponding row group and being electrically connected to each electrode unit 22 of the corresponding row group, so that the temperature detection signal obtained by collecting the combination of each temperature detection unit 34 in the corresponding row group and transmitting the AC signal to each electrode unit 33 in the corresponding row group can be switched in a cycle through the dual-purpose signal line 19 electrically connected thereto. Figure 4 , Figure 5 as well as Figure 1 or Figure 2 As shown, the electrode sheet 13 includes: a substrate 31, a plurality of electrode units 33 electrically connected to the substrate 31 at intervals, a plurality of temperature detection units 34, a plurality of rectifier switching modules 16, and a first cable 15 electrically connected to the substrate 31. The substrate 31 may be a flexible circuit board. The substrate 31 is embedded with a plurality of conductive traces, which include a plurality of grounding wires 18, a multi-channel dual-purpose signal wire 19, and a rectifier ground wire (not numbered) for grounding the plurality of rectifier switching modules 16. The first cable 15 has a plurality of core wires (not shown), each of which is electrically connected to the plurality of grounding wires 18, the multi-channel dual-purpose signal wire 19, and the rectifier ground wire (not numbered) of the substrate 31 in a one-to-one correspondence. In this embodiment, the total number of the grounding wires 18, the dual-purpose signal wires 19, and the rectifier ground wire (not numbered) embedded in the substrate 31 does not exceed 10, so the number of wires of the first cable 15 does not exceed 10.

[0071] The plurality of electrode units 33 are configured into a plurality of row groups and a plurality of column groups. In the present embodiment, 20 electrode units 33 are provided on each electrode sheet 13, and the 20 electrode units 33 are arranged in the order of 1 to 20 in the circuit connection, and the electrode units 33-1 to 33-20 are divided into four row groups and five column groups, that is, the 20 electrode units 33 are arranged in four rows and five columns in the circuit connection. Each electrode unit 33 corresponds to a temperature detection unit 34, and each temperature detection unit 34 has a signal terminal 34-1 and a ground terminal 34-2. The electrode unit 33 and the temperature detection unit 34 are both welded to the substrate 31. Since the plurality of temperature detection units 34 are arranged one-to-one with the plurality of electrode units 33, the plurality of temperature detection units 34 are also arranged in four row groups and five column groups in the circuit connection. It should be noted that the arrangement here is to more clearly show the electrical connection between the electrode sheet 13 and the adapter 20, and does not represent the arrangement of the electrode unit 33 in the spatial structure. Its spatial structure may be as follows Figure 3 The structure shown as an array may also be other structures, such as petal-shaped or scattered, and may be regular or irregular. The electrode unit 33 is configured to apply an alternating electric signal to the patient's tumor site. The temperature detection unit 34 is configured to detect the temperature of the patient's body surface attached to the electrode sheet 13, that is, the temperature at the corresponding electrode unit 33, and output a temperature detection signal to the adapter 20. In this embodiment, the multiplexed signal lines 19 of the substrate 31 are respectively arranged in a one-to-one correspondence with the multiple row groups of the electrode units 33, and are configured to transmit the alternating electric signal generated by the electric field generator 30 to each electrode unit 33 in the corresponding row group. That is, the electrode units 33 in the same row group are connected in parallel to the same conductive trace and then short-circuited through a rectifier switching module 16 corresponding to the row group and the same dual-purpose signal line 19 of the substrate 31. The dual-purpose signal line 19 of the substrate 31 is electrically connected to the first cable 15, and then electrically connected to the electric field generator 30 via the adapter 20. Furthermore, the dual-purpose signal line 19 of the substrate 31 receives the alternating electric signal generated by the electric field generator 30 through the first cable 15 and the adapter 20 .

[0072] The multiple grounding wires 18 are respectively arranged in one-to-one correspondence with the multiple column groups of the electrode unit 33, and the multiple grounding wires 18 are respectively used to short-circuit each corresponding temperature detection unit 34 in each column group to the ground. That is, the grounding terminals 34-2 of the multiple temperature detection units 34 in the same column group are short-circuited with the same grounding wire 18 of the substrate 31, and the grounding terminals 34-2 of the temperature detection units 34 in different column groups are respectively connected in parallel with different grounding wires 18 of the substrate 31. During the time period of temperature detection, only one of the multiple grounding wires 18 is turned on at the same time, and the rest are disconnected. The temperature detection unit 34 includes a temperature sensor 35 having a signal terminal 35-1 and a grounding terminal 35-2 at both ends, respectively. The signal terminal 35-1 of the temperature sensor 35 can be used as the signal terminal 34-1 of the temperature detection unit 34, and the grounding terminal 35-2 of the temperature sensor 35 can be used as the grounding terminal 34-2 of the temperature detection unit 34. The multiple temperature sensors 35 located in the same row group are connected in series, and after a signal terminal 35-1 located at the end of each row group is connected to the first terminal 1 of the rectifier switching module 16 corresponding to the row group, it is connected to the DC power supply VCC through the series-connected bidirectional switch 55 and the voltage divider resistor 53. The grounding terminal 35-2 of each temperature sensor 35 corresponding to each column group is connected to the corresponding diode 36 and then connected to the control switch 54 through a corresponding grounding line 18 in the multiple grounding lines 18 and then connected to the ground pin GND. The tumor electric field treatment system 100 configures the switching timing of the bidirectional switch 55, the rectifier switching module 16 and the control switch 54 so that the analog temperature signals detected by the corresponding one or more combinations of all the temperature sensors 35 of the electrode sheet 13 are sampled respectively or the corresponding electrode unit 13 in the electrode sheet 13 is applied with an AC signal.

[0073] like Figure 4As shown, the bidirectional switching unit (not shown) includes a bidirectional switch 55 corresponding to each row group, and the first end (such as the acquisition end 1) of each bidirectional switch 55 is connected to the detection channel of the corresponding ADC unit 52 as the temperature sampling point of the corresponding row group, and the second end (such as the input end 2) of each bidirectional switch 55 is also connected to the alternating power line 57, and the third end of each bidirectional switch 55 is connected to the dual-purpose signal line 19 corresponding to the corresponding row group. All temperature sensors 35 located in the same row group are connected in series to a dual-purpose signal line 19 (such as one of the dual-purpose signal lines 19-1, 19-2, 19-3, and 19-4) through a rectifier switching module 16 corresponding to the row group, and are connected to a DC power supply VCC through the dual-purpose signal line 19. The grounding terminals 35-2 of all temperature sensors 35 located in the same row group are connected to the ground pin GND by a corresponding grounding line 18 (such as grounding lines 18-1, 18-2, 18-3, 18-4, and 18-5), and the grounding terminals 35-2 of all temperature sensors 35 located in the same column group are connected to the same grounding line 18 (such as grounding lines 18-1, 18-2, 18-3, 18-4, and 18-5). 3, 18-4, 18-5), each row group of temperature sensors 35 are connected in series with a bidirectional switch 55 (such as a bidirectional switch 55-1, 55-2, 55-3 or 55-4) and a voltage divider resistor 53 (such as a voltage divider resistor R1, R2, R3 or R4) at the DC power supply VCC end, and the voltage divider resistor 53 (such as a voltage divider resistor R1, R2, R3 or R4) is closer to the DC power supply VCC end than the bidirectional switch 55 (such as a bidirectional switch 55-1, 55-2, 55-3 or 55-4), and each ground line 18 is connected in series with a control switch 54 (such as a control switch 54-1, 54-2, 54-3, 54-4 or 54-5).

[0074] In this embodiment, when each electrode unit 33 is equipped with a temperature detection unit 34 for temperature detection, the above-mentioned circuit design is used to reduce the number of wires of the first cable 15, so as to avoid the cable becoming thicker and the cable becoming harder, thereby increasing the difficulty of fixing the cable; at the same time, the increase in the number of wires of the first cable 15 is avoided to affect the adhesion effect between the electrode sheet 13 and the corresponding body surface of the patient's tumor site. The ground wire 18, the dual-purpose signal wire 19 and the rectifier ground wire (unnumbered) embedded in the substrate 31 are 10 lines in total. Specifically, in this embodiment, there are 5 ground wires 18 embedded in the substrate 31, 4 dual-purpose signal wires 19, and 1 rectifier ground wire (unnumbered). The number of ground wires 18 is related to the number of column groups N of the electrode unit 33, which is equal to the number of column groups of the electrode unit 33, and N is a positive integer. The number of dual-purpose signal wires 19 is related to the number of row groups M of the electrode unit 33, which is equal to the number of row groups of the electrode unit 33, and M is a positive integer. The number L of the conductive traces electrically connecting the first cable 15 and the substrate 31 of the electrode sheet 13 is equal to the sum of the number of the rectifier ground wire (unnumbered), the ground wire 18 and the dual-purpose signal wire 19 .

[0075] The plurality of electrode units 33 are arranged on the substrate 31 in a two-dimensional array. Figure 3As shown, the electrode sheet 13 in this embodiment includes 20 electrode units 33, and the 20 electrode units 33 are arranged in an array of four rows and six columns. The first row and the fourth row are each provided with four electrode units 33, and the second row and the third row are each provided with six electrode units 33. The four electrode units 33 in each row of the first row and the fourth row are all located in each column of the second column to the fifth column, and the six electrode units 33 in each row of the second row and the third row are all located in each column of the first column to the sixth column. When an alternating current signal is applied to each electrode unit of the electrode sheet for a long time, the temperature rise of the skin on the surface of the body corresponding to each electrode unit at the application site detected by the temperature detection unit corresponding to each electrode unit is inconsistent due to the different positions and heat generation of each electrode unit. When it is detected that the surface temperature corresponding to some electrode units quickly reaches or exceeds the safety threshold temperature set by the tumor electric field treatment system, in order to avoid low-temperature burns on the patient's body surface, the electric field generator of the tumor electric field treatment system will stop transmitting the alternating current signal to all electrode units on the electrode sheet, but this operation will shorten the effective time of applying the alternating current signal to each electrode unit 33. To overcome this problem, the electrode sheet 13 in this embodiment performs partition control on each electrode unit 33 according to the location of each electrode unit 33 and the temperature change detected by the temperature detection unit 34 when each electrode unit 33 applies an AC signal, so as to increase the effective time of each electrode unit 33 of the electrode sheet 13 applying an AC signal without causing low-temperature burns on the patient's body surface. In this embodiment, the 20 electrode units 33 are divided into four areas in terms of spatial structure: area 1 to area 4. Specifically, two electrode units 33 located in the first row, second column and the first row, third column and three electrode units 33 located in the second row, first column, second row, second column and second row, third column are divided into region 1, two electrode units 33 located in the first row, fourth column and first row, fifth column and third row, sixth column are divided into region 2, three electrode units 33 located in the third row, second column and third row, third column and two electrode units 33 located in the fourth row, second column and fourth row, third column are divided into region 3, three electrode units 33 located in the third row, fourth column, third row, fifth column and third row, sixth column and two electrode units 33 located in the fourth row, fourth column and fourth row, fifth column are divided into region 4. In terms of circuit connection, each region (1-4) corresponds to a row group. In some other embodiments, the 20 electrode units 33 may also be arranged or divided into regions in other ways. Of course, in some other embodiments, the electrode sheet 13 may also have other numbers of electrode units 33. In short, the implementation of the present application is not limited by the number and arrangement of the electrode units 33 of the electrode sheet 13 .

[0076] Each electrode unit 33 can apply an alternating electric signal, and the electrode sheets 13 configured in pairs are used to apply an alternating electric field to the patient's tumor site. Optionally, the electrode unit 33 is a dielectric element, such as a ceramic sheet, or a polymer dielectric layer composed of a polymer material. Each temperature detection unit 34 is set corresponding to an electrode unit 33 to detect the temperature at the corresponding electrode unit 33. Each temperature detection unit 34 can be set at any position of the corresponding electrode unit 33, such as Figure 4 and Figure 5 As shown, in this embodiment, each electrode unit 33 is provided with a through hole 331, and the through hole 331 is suitable for installing the temperature detection unit 34. For example, the middle of each electrode unit 33 has a through hole 331, and each through hole 331 of the electrode unit 33 accommodates a corresponding temperature detection unit 34. Each temperature detection unit 34 also includes a diode 36 connected in series with the temperature sensor 35 to prevent the reverse flow of current from causing other temperature sensors 35 to affect the accuracy of the temperature signal detected by the temperature sensor 35. In terms of spatial structure, the diode 36 can be arranged in the through hole 331 of the electrode unit 33 together with the temperature sensor 35.

[0077] Each diode 36 has an anode 36-1 and a cathode 36-2. The ground terminal 35-2 of the temperature sensor 35 of each temperature detection unit 34 is connected in series with the anode 36-1 of the corresponding diode 36. Two adjacent temperature detection units 34 in the same row are connected in series with the cathode 36-2 of the diode 36 of the other temperature detection unit 34 through the signal terminal 35-1 of the temperature sensor 35 of one temperature detection unit 34 to realize the series connection between the two temperature detection units 34. In each column group, the anode 36-1 of the diode 36 of each temperature detection unit 34 is respectively connected to the ground terminal 35-2 of the corresponding temperature sensor 35, and the cathode 36-2 of the diode 36 of each temperature detection unit 34 is connected together through the corresponding control switch 54 to the ground pin GND. At this time, the cathode 36-2 of the diode 36 serves as the ground terminal 34-2 of the temperature detection unit 34, and the signal terminal 35-1 of the temperature sensor 35 serves as the signal terminal 34-1 of the temperature detection unit 34. The temperature sensor 35 can be a thermistor or other temperature sensors other than thermistors.

[0078] like Figure 4As shown, the electrode sheet 13 of this embodiment includes 5 grounding wires 18, each of which is used to ground the grounding ends 34-2 of the temperature detection units 34 of the same column group. The 5 grounding wires 18 of the electrode sheet 13 are respectively a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, a fourth grounding wire 18-4 and a fifth grounding wire 18-5. Among the five column groups of the electrode sheet 13, the first column group includes electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16; the second column group includes electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17; the third column group includes electrode unit 33-3, electrode unit 33-8, electrode unit 33-13, and electrode unit 33-18; the fourth column group includes electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19; and the fifth column group includes electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20.Specifically, the first grounding line 18-1 is used to ground the temperature detection units 34 corresponding to the electrode units 33-1, 33-6, 33-11, and 33-16 in the first column group; the second grounding line 18-2 is used to ground the two temperature detection units 34 in the first row group corresponding to the electrode units 33-1 and 33-2 respectively and connected in series, the two temperature detection units 34 in the second row group corresponding to the electrode units 33-6 and 33-7 respectively and connected in series, the two temperature detection units 34 in the third row group corresponding to the electrode units 33-11 and 33-12 respectively and connected in series, and the The two temperature detection units 34 in the four-row group that correspond to the electrode unit 33-16 and the electrode unit 33-17 respectively and are connected in series are grounded together; the third grounding line 18-3 is used to connect the three temperature detection units 34 in the first row group that correspond to the three electrode units 33 from electrode unit 33-1 to electrode unit 33-3 respectively and are connected in series, the three temperature detection units 34 in the second row group that correspond to the three electrode units 33 from electrode unit 33-6 to electrode unit 33-8 respectively and are connected in series, the three temperature detection units 34 in the third row group that correspond to the three electrode units 33 from electrode unit 33-11 to electrode unit 33-13 respectively and are connected in series, and the three temperature detection units 34 in the third row group that correspond to the three electrode units 33 from electrode unit 33-11 to electrode unit 33-13 respectively and are connected in series, and the three temperature detection units 34 in the fourth row group that correspond to the three electrode units 33 from electrode unit 33-11 to electrode unit 33-13 respectively and are connected in series. The three temperature detection units 34 in the fourth row group that correspond to the electrode units 33-16 to the electrode units 33-18 and are connected in series are grounded together; the fourth grounding line 18-4 is used to connect the four temperature detection units 34 in the first row group that correspond to the electrode units 33-1 to the electrode units 33-4 and are connected in series, the four temperature detection units 34 in the second row group that correspond to the electrode units 33-6 to the electrode units 33-9 and are connected in series, the four temperature detection units 34 in the third row group that correspond to the electrode units 33-11 to the electrode units 33-14 and are connected in series, and the four temperature detection units 34 in the fourth row group that correspond to the electrode units 33-16 to the electrode units 33-1 9 respectively and connected in series with the four temperature detection units 34 are commonly grounded; the fifth grounding line 18-5 is used to connect the five temperature detection units 34 located in the first row group and corresponding to the electrode units 33-1 to 33-5 respectively and connected in series, the five temperature detection units 34 located in the second row group and corresponding to the electrode units 33-6 to 33-10 respectively and connected in series, the five temperature detection units 34 located in the third row group and corresponding to the electrode units 33-11 to 33-15 respectively and connected in series, and the five temperature detection units 34 located in the fourth row group and corresponding to the electrode units 33-16 to 33-20 respectively and connected in series to the ground.It should be noted that these grounding wires 18 can be selectively closed or disconnected, for example, by connecting each grounding wire 18 in series with a control switch 54, that is, the grounding end 34-1 of the temperature detection unit 34 corresponding to each electrode unit 33 in each column group is connected to the ground pin GND through a control switch 54, which will be described in detail below. Figure 5 , after the grounding end 35-1 of the corresponding temperature sensor 35 in each column group is connected to the anode 36-1 of the corresponding diode 36, they are connected together through the cathode 36-2 of the corresponding diode 36. In short, each grounding line 18 short-circuits the grounding ends 34-2 of each temperature detection unit 34 corresponding to all electrode units 33 in the corresponding column group through the corresponding diode 36 and grounds them.

[0079] like Figure 4As shown, the electrode sheet 13 of this embodiment also includes 4 dual-purpose signal lines 19, one end of each dual-purpose signal line 19 is respectively connected to all the electrode units 33 connected in parallel in each row group and the temperature detection units 34 connected in series in each row group through the corresponding rectification switching module 16 (for example, after all the temperature detection units 34 in each row group are connected in series, a temperature detection unit 34 located at the end is connected to one end of the dual-purpose signal line 19 corresponding to the row group through the rectification switching module 16), and the other end of each dual-purpose signal line 19 is connected to the adapter 20 for receiving the temperature detection signal and transmitting the alternating electrical signal. Specifically, the 4 dual-purpose signal lines 19 of the electrode sheet 13 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3 and a fourth dual-purpose signal line 19-4. The five electrode units 33 from electrode unit 33-1 to electrode unit 33-5 are connected in parallel and connected to the first dual-purpose signal line 19-1 through the corresponding rectifying switching module 16, and the temperature detection units 34 corresponding to the five electrode units 33 from electrode unit 33-1 to electrode unit 33-5 are connected in series and also connected to the first dual-purpose signal line 19-1 through the rectifying switching module 16; the five electrode units 33 from electrode unit 33-6 to electrode unit 33-10 are connected in parallel and connected to the second dual-purpose signal line 19-2 through the corresponding rectifying switching module 16, and the temperature detection units 34 corresponding to the five electrode units 33 from electrode unit 33-6 to electrode unit 33-10 are connected in series and connected to the second dual-purpose signal line 19-2 through the rectifying switching module 16; The five electrode units 33 from the electrode unit 33-11 to the electrode unit 33-15 are connected in parallel and connected to the third dual-purpose signal line 19-3 through the corresponding rectifying and switching modules 16, and the temperature detection units 34 corresponding to the five electrode units 33 from the electrode unit 33-11 to the electrode unit 33-15 are connected in series and connected to the third dual-purpose signal line 19-3 through the rectifying and switching modules 16; the five electrode units 33 from the electrode unit 33-16 to the electrode unit 33-20 are connected in parallel and connected to the fourth dual-purpose signal line 19-4 through the corresponding rectifying and switching modules 16, and the temperature detection units 34 corresponding to the five electrode units 33 from the electrode unit 33-16 to the electrode unit 33-20 are connected in series and connected to the fourth dual-purpose signal line 19-4 through the rectifying and switching modules 16. In short, each dual-purpose signal line 19 connects the electrode units 33 in the same row group in parallel and connects the temperature detection units 34 corresponding to the electrode units 33 in the same row group in series through the corresponding rectifying and switching modules 16, and then connects to the external device. It should be noted that these dual-purpose signal lines 19 can selectively transmit alternating electrical signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switch 55 and a rectifier switching module 16 and coordinating the closing or opening of the ground line 18.That is, after the electrode units 33 in each row group are connected in parallel and the temperature detection units 34 in each row group are connected in series, they are connected to a corresponding bidirectional switch 55 in the bidirectional switching unit (not labeled) through a dual-purpose signal line 19. Each of the multiple bidirectional switches 55 of the bidirectional switching unit (not labeled) is configured to switch the dual-purpose signal line 19 to connect to the temperature sampling point (not labeled) or the alternating power line 57, so that when the dual-purpose signal line 19 is connected to the temperature sampling point (not labeled), the switch state of the switch 54 is configured to make the temperature detection signal detected by the corresponding temperature detection unit 34 in each column group be sampled based on the temperature sampling point (not labeled), or when the dual-purpose signal line 19 is connected to the alternating power line 57, the electrode units 33 in at least one row group are applied with an alternating electrical signal based on the alternating power line 57, which will be described in detail below.

[0080] like Figure 4 As shown, the electrode sheet 13 of this embodiment also includes a plurality of rectifier switching modules 16, each rectifier switching module 16 is respectively arranged corresponding to a row group. Each rectifier switching module 16 includes an electromagnetic control switch 162 having a first end 1, a second end 2 and a third end 3, a rectifier bridge 161 and a voltage regulator tube 163. The first end of the electromagnetic control switch 162 constitutes the first end of the rectifier switching module 16, the second end 2 of the electromagnetic control switch 162 constitutes the second end of the rectifier switching module 16, and the third end 3 of the electromagnetic control switch 162 and the first end of the rectifier bridge 161 are connected to form the third end of the rectifier switching module 16. The electromagnetic control switch 162 can be a relay or a thyristor. Each temperature detection unit 34 in each row group is connected in series and then connected to the first end of the corresponding rectifier switching module 16, each electrode unit 33 in each row group is connected in parallel and then connected to the second end of the corresponding rectifier switching module 16, and the third end of the rectifier switching module 16 corresponding to each row group is connected to a dual-purpose signal line 19 corresponding to each row group. Taking the first row group as an example, the temperature detection units 34 corresponding to the electrode units 33-1 to 33-5 in the first row group are connected in series and then connected to the first end of the corresponding rectifier switching module 16, the electrode units 33-1 to 33-5 are connected in parallel and then connected to the second end of the corresponding rectifier switching module 16, and the third end of the rectifier switching module 16 corresponding to the first row group is connected to the first dual-purpose signal line 19-1 corresponding to the first row group.

[0081] The rectifier bridge 161 includes a first end 1, a second end 2, a third end 3 and a fourth end 4. Taking the first row group as an example, the first end 1 of the rectifier bridge 161 is connected to the dual-purpose signal line 19-1 corresponding to the first row group and the third end 3 of the electromagnetic control switch 162, and a voltage regulator tube 163 is connected in series between the second end of the rectifier bridge 161 and the fourth end of the rectifier bridge 161, and the third end of the rectifier bridge 161 is connected to the ground pin GND. The anode of the voltage regulator tube 163 is connected to the fourth end of the rectifier bridge 161, and the cathode of the voltage regulator tube 163 is connected to the second end of the rectifier bridge 161. The voltage regulator tube 163 can be a diode.

[0082] The electromagnetic control switch 162 corresponding to each row group is set in linkage with the bidirectional switch 55 corresponding to the row group. Taking the first row group as an example, when the bidirectional switch 55-1 corresponding to the first row group is switched to its first end 1, the electromagnetic control switch 162 corresponding to the first row group is switched to its first end 1 so that the third end 3 of the electromagnetic control switch 162 is connected to its first end 1 and disconnected from its second end 2, so that the analog temperature signals detected by the temperature detection units 34 corresponding to one or more combinations are sampled respectively according to the switch state of the configuration control switch 54. When the bidirectional switch 55-1 corresponding to the first row group is switched to its second end 2, the electromagnetic control switch 162 corresponding to the first row group is switched to its second end 2 so that the third end 3 of the electromagnetic control switch 162 is disconnected from its first end 1 and connected to its second end 2, so that all electrode units 33 of the first row group are simultaneously applied with alternating electrical signals based on the alternating power line 57, and at this time, all control switches 54 are in the disconnected state. The linkage setting principle of the electromagnetic control switches 162 and the bidirectional switches 55 corresponding to the second to fourth row groups is the same as the linkage method of the electromagnetic control switches 162 and the bidirectional switches 55 corresponding to the first row group.

[0083] The tumor electric field treatment system 100 of this embodiment includes at least one pair of the above-mentioned electrode sheets 13, an adapter 20 electrically connected to the electrode sheets 13, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheets 13 and the electric field generator 30. The electric field generator 30 provides an alternating electric signal to a plurality of electrode units 33 of the electrode sheet 13 via the adapter 20 and the dual-purpose signal line 19 of the electrode sheet 13, or is used to receive the temperature detection signal output by the temperature detection unit 34 corresponding to the plurality of electrode units 33. The adapter 20 transmits the alternating electric signal generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode sheet 13, and is also configured to receive the temperature detection signal output by the multiplex dual-purpose signal line 19 of the electrode sheet 13.

[0084] refer to Figure 4As shown, the adapter 20 includes: a first controller 51, multiple groups of ADC units 52 connected to the first controller 51, multiple groups of piezoelectric resistors 53 and multiple groups of control switches 54 corresponding to the multiple groups of ADC units 52, multiple groups of bidirectional switching switches 55 corresponding to the multiple groups of ADC units 52, a first communication unit 56, an alternating power line 57 corresponding to each group of bidirectional switching switches 55, and a first power module 58 connected to the first communication unit 56, the first controller 51 and the multiple groups of ADC units 52, and the first power module 58 provides a DC power supply VCC for each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unnumbered), and the corresponding circuit lines (unnumbered) in the multiple circuit lines (unnumbered) are electrically connected to the multiple ground lines 18, the multiplexed signal lines 19 and the rectifier ground line (unnumbered) in the substrate 31 of the electrode sheet 13 through the first cables 15 of the corresponding electrode sheet 13. The multiple circuit lines (unnumbered) include multiple alternating power lines 57 that transmit alternating electrical signals to the corresponding electrode sheets 13 and are electrically connected to the dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode sheets 13, multiple circuit lines (unnumbered) that are electrically connected one-to-one with the dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode sheets 13 and are used to supply power to the temperature detection units 34 of the electrode sheets 13 or to transmit the temperature detection signals of the electrode sheets 13, multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple ground lines 18 in the substrate 31 of the corresponding electrode sheets 13, and one circuit line (unnumbered) that is electrically connected to the rectifier ground lines (unnumbered) of each rectifier switching module 16. The number L of circuit lines electrically connected between the adapter 20 and the first cable 15 of the electrode sheet 13 is equal to the sum of the number of rows and the number of columns of the electrode units 33 of the electrode sheet 13 plus one; the number H of circuits electrically connected between the adapter 20 and the first cables 15 of each of X electrode sheets 13 is equal to X times the number of circuit lines electrically connected to a single electrode sheet 13, that is, H=XL=X*(M+N+1). The number of groups of control switches 54 and the number of groups of bidirectional switching switches 55 are both related to the number of electrode sheets 13. The number of groups of control switches 54 is the same as the number of groups of bidirectional switching switches 55, and is not less than the number of electrode sheets 13. Optionally, the number of groups of control switches 54 and bidirectional switching switches 55 is the same as the number of electrode sheets 13. The following is a detailed description taking only the electrical connection between an electrode sheet 13 having 20 electrode units 33 and the adapter 20 as an example.

[0085] Each group of control switches 54 is provided with a plurality of control switches 54, which are respectively connected to the adapter 20 and are respectively electrically connected to circuit lines (not numbered) corresponding to the multi-way grounding lines 18 of a corresponding electrode sheet 13, and are configured to control the conduction or disconnection of the multi-way grounding lines 18. The circuit lines (not numbered) of the multi-way grounding lines 18 electrically connected to the electrode sheets 13 are grounded at one end close to the control switches 54. The number of control switches 54 in each group of control switches 54 is related to the number of grounding lines 18 of the substrate 31 of the corresponding electrode sheet 13, and the two are equal in this embodiment. Figure 4As shown, in the present embodiment, the plurality of control switches 54 are respectively a first control switch 54-1, a second control switch 54-2, a third control switch 54-3, a fourth control switch 54-4 and a fifth control switch 54-5. The plurality of control switches 54 in the same group respectively control the closing or disconnection of the corresponding grounding line 18 of the same electrode sheet 13. The first control switch 54-1 is used to control the closing or disconnection of the first grounding line 18-1 of the corresponding electrode sheet 13, and further can cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature detection unit 34 corresponding to the four electrode units 33 in the first column group of the electrode sheet 13, namely, the electrode unit 33-1, the electrode unit 33-6, the electrode unit 33-11 and the electrode unit 33-16; the second control switch 54-2 is used to control the closing or disconnection of the second grounding line 18-2 of the electrode sheet 13, and further can cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of the temperature detection units 34 corresponding to the four electrode units 33 in the first column group of the electrode sheet 13. The temperature detection units 34 corresponding to the electrode units 33-1 and 33-2, electrode units 33-6 and 33-7, electrode units 33-11 and 33-12, electrode units 33-16 and 33-17 in the first column group and the second column group of the electrode sheet 13 are powered on and off; the third control switch 54-3 is used to control the closing or disconnection of the third grounding line 18-3 of the electrode sheet 13, and can then cooperate with the corresponding group of bidirectional switching switches 55 to control the electrode units in each column group from the first column group to the third column group of the electrode sheet 13 The temperature detection units 34 corresponding to the electrode units 33-1 to 33-3, the electrode units 33-6 to 33-8, the electrode units 33-11 to 33-13, and the electrode units 33-16 to 33-18 are powered on and off; the fourth control switch 54-4 is used to control the closing or disconnection of the fourth grounding line 18-4 of the electrode sheet 13, and can cooperate with the corresponding group of two-way switching switches 55 to control the electrode units 33-1 to 33-4, the electrode units 33-6 to 33-8, the electrode units 33-11 to 33-13, and the electrode units 33-16 to 33-18 in each column group of the electrode sheet 13. -6 to electrode unit 33-9, electrode unit 33-11 to electrode unit 33-14, electrode unit 33-16 to electrode unit 33-19, and each temperature detection unit 34 corresponding to the electrode unit 33-1 is powered on or off; the fifth control switch 54-5 is used to control the closing or disconnection of the fifth grounding line 18-5 of the electrode sheet 13, and then can cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature detection unit 34 corresponding to the electrode unit 33-1 electrode unit 33-20 in each column group from the first column group to the fifth column group of the electrode sheet 13. The above-mentioned control switch 54 can be a mechanical switch, such as a relay. The control switch 54 can also be an electronic switch, and each control switch 54 can be opened and closed by an additional first controller 51.

[0086] In this embodiment, the multiple groups of control switches 54 are all electronic switches. The first controller 51 is connected to the multiple groups of control switches 54 for sequentially and cyclically controlling the on and off states of multiple control switches 54 in each group of control switches 54, and then sequentially and individually conducting each of the multiple grounding wires 18 of the corresponding electrode sheet 13 and cooperating with the switching of the corresponding bidirectional switch 55 to collect the temperature detection signals detected by all the temperature detection units 34 on the electrode sheet 13. The number of each group of control switches 54 is the same as the number of grounding wires 18 of the corresponding electrode sheet 13.

[0087] Each set of two-way switches 55 is provided with a plurality of two-way switches 55, and the plurality of two-way switches 55 in each set are respectively connected to the adapter 20 and are respectively electrically connected to the circuit lines (not numbered) corresponding to the multiplex dual-purpose signal lines 19 of the corresponding electrode sheet 13. The number of two-way switches 55 in each set of two-way switches 55 is related to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13, which is equal to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13. Each bidirectional switching switch 55 has an acquisition terminal 1 and an input terminal 2. The acquisition terminal 1 of multiple bidirectional switching switches 55 in the same group is electrically connected to the corresponding detection channels of multiple detection channels of a corresponding group of ADC units 52 as a corresponding temperature sampling point (unnumbered). The input terminal 2 of each bidirectional switching switch 55 in the same group is electrically connected to the corresponding same alternating power line 57, and is configured to control the multi-channel dual-purpose signal line 19 to connect to the corresponding alternating power line 57 to transmit the alternating electrical signal or to connect to the corresponding detection channel of the corresponding group of ADC units 52 to receive the temperature detection signal output by the temperature detection unit 34. Each bidirectional switching switch 55 can also include a third terminal (unnumbered) electrically connected to the corresponding dual-purpose signal line 19.

[0088] like Figure 4As shown, taking an electrode sheet 13 electrically connected to the adapter 20 as an example, in this embodiment with 20 electrode units 33, the plurality of bidirectional switches 55 are respectively a first bidirectional switch 55-1, a second bidirectional switch 55-2, a third bidirectional switch 55-3 and a fourth bidirectional switch 55-4. The plurality of bidirectional switches 55 in the same group respectively control a corresponding one of the multiplexed signal lines 19 of the same electrode sheet 13 to switch between transmitting the alternating electric signal and transmitting the temperature detection signal. Specifically, the first bidirectional switch 55-1 can be linked with the rectifier switching module 16 corresponding to the first row group of the electrode sheet 13 and cooperate with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to control the first dual-purpose signal line 19-1 of the corresponding electrode sheet 13 to conduct the electrode units 33-1 to 33-5 in the first row group to transmit the alternating electrical signal to the electrode units 33-1 to 33-5 in the first row group or to conduct the signal ends 34-2 of the temperature detection units 34 corresponding to the electrode units 33-1 to 33-5 in the first row group so that the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 34 corresponding to the electrode units 33 are sampled and output to the corresponding ADC unit 52. The second bidirectional switch 55-2 can control the second dual-purpose signal line 19-2 of the corresponding electrode sheet 13 in conjunction with the rectifier switching module 16 corresponding to the second row group of the electrode sheet 13 and in cooperation with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to conduct the electrode unit 33-6 to the electrode unit 33-10 in the second row group to transmit the alternating electrical signal to the electrode unit 33-6 to the electrode unit 33-10 in the second row group or conduct the signal end 34-2 of each temperature detection unit 34 corresponding to the electrode unit 33-6 to the electrode unit 33-10 in the second row group so that the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 34 corresponding to the electrode units 33 are sampled and output to the corresponding ADC unit 52 respectively;The third bidirectional switch 55-3 can be linked with the rectifier switch module 16 corresponding to the third row group of the electrode sheet 13 and cooperate with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to control the third dual-purpose signal line 19-3 of the corresponding electrode sheet 13 to make the electrode units 33-11 to 33-15 in the third row group conductive to transmit alternating electrical signals to the electrode units 33-11 to 33-15 in the third row group or to make the signal ends 34-2 of each temperature detection unit 34 corresponding to the electrode units 33-11 to 33-15 in the third row group conductive so that the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 34 corresponding to the electrode units 33 are sampled and output to the corresponding ADC unit 52 respectively; The fourth bidirectional switch 55-4 can control the fourth dual-purpose signal line 19-4 of the corresponding electrode sheet 13 in linkage with the rectifier switching module 16 corresponding to the fourth row group of the electrode sheet 13 and in cooperation with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to conduct the electrode unit 33-16 to the electrode unit 33-20 in the fourth row group to transmit the alternating electrical signal to the electrode unit 33-16 to the electrode unit 33-20 in the fourth row group or conduct the signal end 34-2 of each temperature detection unit 34 corresponding to the electrode unit 33-16 to the electrode unit 33-20 in the fourth row group so that the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 34 corresponding to the electrode units 33 are sampled and output to the corresponding ADC unit 52. ;

[0089] When the input terminals 2 of each bidirectional switch 55 in each group of bidirectional switches are all turned on, the collection terminals 1 are all turned off, the third terminals of the corresponding rectifier switching modules 16 are also connected to the second terminals, and the control switches 54 in the corresponding group of control switches 54 are all turned off, the alternating electrical signals can be transmitted to the electrode units 33 in the corresponding row groups of the corresponding electrode sheets 13; when the collection terminals 1 of each bidirectional switch 55 in each group of bidirectional switches 55 are turned on in sequence in time-sharing, the input terminals 2 are all turned off, and the third terminals of the corresponding rectifier switching modules 16 are all connected to the first terminals, the temperature detection signals collected by the temperature detection units 35 of the temperature detection units 34 corresponding to the electrode units 33 on the electrode sheets 13 can be transmitted in time-sharing with the control switches 54 in the corresponding group of control switches 54. The above-mentioned bidirectional switch 55 can be a mechanical switch, such as a relay. The bidirectional switch 55 can also be an electronic switch, and each bidirectional switch 55 can be switched by an additional first controller 51.

[0090] In this embodiment, the plurality of groups of two-way switches 55 are all electronic switches. The first controller 51 is in communication connection with the plurality of groups of two-way switches 55, and is used to control the plurality of two-way switches 55 in each group of two-way switches 55 to switch between their respective acquisition terminals 1 and input terminals 2, and to control the third terminal 3 of the electromagnetic control switch 162 in the corresponding rectifier switching module 16 to switch between being connected to the first terminal and being connected to the second terminal 2, and to cooperate with the closing or opening of the corresponding control switch 54, so as to continuously monitor the temperature of the patient's body surface detected by all the temperature detection units 34 on the electrode sheet 13 or to transmit the alternating electrical signal to the patient through each electrode unit 33.

[0091] In this embodiment, each group of ADC units 52 is electrically connected to the collection terminals 1 of the plurality of bidirectional switches 55 in the corresponding group of bidirectional switches 55 through the multi-channel circuit lines (not numbered) in the adapter 20, and is configured to receive the temperature detection signal transmitted by the multi-channel dual-purpose signal line 19 of the corresponding electrode sheet 13, and convert the temperature detection signal from an analog signal to a digital signal. Figure 4 As shown, each group of ADC units 52 includes 4 detection channels A, B, C, and D, which are the first detection channel A, the second detection channel B, the third detection channel C, and the fourth detection channel D. Each detection channel A, B, C, and D is used to connect a corresponding dual-purpose signal line 19 in the multiple dual-purpose signal lines 19 through the corresponding bidirectional switch 55. Specifically, the first detection channel A is connected to the first dual-purpose signal line 19-1 through the acquisition terminal 1 of the first bidirectional switch 55-1, the second detection channel B is connected to the second dual-purpose signal line 19-2 through the acquisition terminal 1 of the second bidirectional switch 55-2, the third detection channel C is connected to the third dual-purpose signal line 19-3 through the acquisition terminal 1 of the third bidirectional switch 55-3, and the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 through the acquisition terminal 1 of the fourth bidirectional switch 55-4. Each detection channel A, B, C, and D is used to receive the temperature detection signal collected by the temperature detection unit 34 corresponding to each electrode unit 33 in the row group connected to the corresponding dual-purpose signal line 19. In addition, each detection channel A, B, C, D is connected to a first power module 58 for providing a detection voltage to the detection channel A, B, C, D via a corresponding voltage divider resistor 53 in the adapter 20. The first power module 58 provides direct current.

[0092] In this embodiment, the first communication unit 56 is configured to obtain the digital signals output by the multiple groups of ADC units 52 and send the digital signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage of the alternating electric signal provided to the multiple electrode units 33 of the electrode sheet 13 according to the received digital signal. Exemplarily, when any of the multiple digital signals received exceeds the preset threshold, it means that the temperature detected by the temperature detection unit 34 corresponding to at least one electrode unit 33 in the electrode sheet 13 exceeds the preset temperature threshold (for example, 41°C, 42°C, etc.), and at this time, the voltage of the alternating electric signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode unit 33 of the electrode sheet 13 from causing low-temperature burns to the patient's skin when the alternating electric signal is applied due to excessive temperature. The above-mentioned preset temperature threshold and preset threshold can be determined according to the human safety threshold. The first communication unit 56 is controlled by the first controller 51 and transmits the digital signals converted by the multiple groups of ADC units 52 in series. In this embodiment, the preset temperature threshold can be a value within 36°C-45°C.

[0093] refer to Figure 6 and Figure 7 In this embodiment, the first power module 58 is electrically connected to the second power module 32 of the electric field generator 30, and is configured to supply power to the first controller 51, the multiple ADC units 52, and the first communication unit 56 of the adapter 20. A first connector 60 is connected between each electrode sheet 13 and the adapter 20, and the first connector 60 is suitable for connecting the corresponding electrode sheet 13 to the adapter 20. Figure 1 As shown, the first connector 60 includes a first plug 61 provided at one end of the first cable 15 away from the electrode sheet 13 and a first socket 62 provided on the adapter 20. The first plug 61 and the first socket 62 are push-type spring connectors, that is, the first connector 60 uses a connector to connect the adapter 20 with the electrode sheet 13. Each first cable 15 has four wires electrically connected to four bidirectional switches 55 in the corresponding group of bidirectional switches 55, five wires electrically connected to five control switches 54 in the corresponding group of control switches 54, and one wire connected to the rectifier ground wire (not numbered) short-circuited at the third end of the rectifier bridge 161 of each rectifier switching module 16 in the corresponding group, that is, each first connector 60 is electrically connected to a corresponding group of bidirectional switches 55 and a corresponding group of control switches 54 of the adapter 20 through nine of the ten wires, and is connected to the electric field generator 30 through a corresponding alternating power line 57 of the adapter 20.

[0094] A second connector 70 is provided between the adapter 20 and the electric field generator 30, and the second connector 70 is suitable for connecting the electric field generator 30 to the adapter 20. Figure 1As shown, the adapter 20 also includes a second cable 25 connected to the second connector 70. The second connector 70 includes a second plug 71 provided at an end of the second cable 25 away from the first controller 51 and a second socket 72 provided on the electric field generator 30. The second plug 71 and the second socket 72 are push-type spring connectors, that is, the second connector 70 uses a connector to connect the adapter 20 to the electric field generator 30. Each first connector 60 such as X1, Y1, X2 and Y2 is connected to the second connector 70 through a corresponding alternating power line 57, and the first connector 60 such as X1, Y1, X2 and Y2 is also connected to a corresponding group of control switches 54 and a corresponding group of ADC units 52, wherein each first connector 60 is connected to the second connector 70 and a corresponding group of ADC units 52 through a corresponding group of bidirectional switching switches 55. The second cable 25 has 8 conductors, including 4 conductors 1 to 4 electrically connected to the corresponding alternating power lines 57 and used to transmit alternating electrical signals, a conductor 5 electrically connected to the data receiving line RX of the first communication unit 56, a conductor 6 electrically connected to the data sending line TX of the first communication unit 56, a conductor 7 electrically connected to the VCC power line of the first power module 58, and a conductor 8 electrically connected to the GND line of the first power module 58. The second connector 70 is connected to the first communication unit 56 through the data receiving line RX and the data sending line TX, the VCC pin of the second connector 70 is connected to the VVC power line of the first power module 58, the GND pin of the second connector 70 is connected to the GND line of the first power module 58 and grounded, and the VCC pin of the second connector 70 is also connected to the corresponding group of voltage dividers 53 and the corresponding group of ADC units 52 through the VCC power line of the first power module 58.

[0095] refer to Figure 6 and Figure 8The electric field generator 30 includes: a second power supply module 32, a second controller 37, an AC signal generator 39, a second communication unit 38 and a group of power switches 40. The VCC pin of the second connector 70 is also electrically connected to the VCC power line of the second power supply module 32, and the GND pin of the second connector 70 is grounded through the GND line of the second power supply module 32. The second power supply module 32 is also connected to the second controller 37 and the AC signal generator 39 respectively and supplies power to them. The second communication unit 38 is electrically connected to the wire 5 of the second connector 70 through its data receiving line RX and is electrically connected to the wire 6 of the second connector 70 through its data sending line TX, thereby realizing information interaction between the electric field generator 30 and the adapter 20. The second controller 37 is also electrically connected to the second communication unit 38, the AC signal generator 39 and a group of power switches 40. The second controller 37 is configured to control the opening and closing of each power switch 40 in the group of power switches 40 and adjust the relevant parameters of the alternating electric signal applied by the AC signal generator 39 according to the relevant digital signal received by the second communication unit 38 from the adapter 20. The AC signal generator 39 is electrically connected to the wires 1 to 4 of the second connector 70 for transmitting the alternating electric signal through the group of power switches 40. The group of power switches 40 includes a plurality of power switches 40, and the plurality of power switches 40 are arranged in a one-to-one correspondence with the plurality of electrode sheets 13. Each power switch 40 is electrically connected to a corresponding wire 1, 2, 3, 4 for transmitting the alternating electric signal in the second connector 70 through an AC power line 41-1, 41-2, 41-3, 41-4 and is electrically connected to the corresponding electrode sheet 13 through the corresponding wires 1, 2, 3, 4 of the second connector 70, so as to transmit the alternating electric signal to each electrode sheet 13. The AC signal generator 39 is electrically connected to the group of power switches 40 through a plurality of AC power lines 41. Specifically, the number of power switches 40 of the electric field generator 30 is related to the number of electrode sheets 13. In this embodiment, the number of power switches 40 is equal to the number of electrode sheets 13 and both are 4. The power switches 40 include a first power switch 40-1, a second power switch 40-2, a third power switch 40-3, and a fourth power switch 40-4, which are electrically connected to the wires 1 to 4 of the second connector 70 in a one-to-one correspondence.One end of the first power switch 40-1 is electrically connected to the AC signal generator 39 through the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 1 for transmitting the alternating electric signal in the second connector 70 through an AC power line 41-1, and is electrically connected to the alternating power line 57 at the port X1 of the adapter 20 through the wire 1 of the second connector 70, the alternating power line 57 at the port X1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits the alternating electric signal to the electrode sheet 13 electrically connected to the port X1 of the adapter 20 One end of the second power switch 40-2 is electrically connected to the AC signal generator 39 through the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 2 for transmitting alternating electric signals in the second connector 70 through an AC power line 41-2, and is electrically connected to the alternating power line 57 of the adapter 20 at the port Y1 through the wire 2 of the second connector 70, the alternating power line 57 of the adapter 20 at the port Y1 is electrically connected to the first connector 60, and the first connector 60 at the port Y1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits an alternating electric signal to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20 One end of the third power switch 40-3 is electrically connected to the AC signal generator 39 through the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 3 for transmitting alternating electric signals in the second connector 70 through an AC power line 41-3, and is electrically connected to the alternating power line 57 of the adapter 20 at the port X2 through the wire 3 of the second connector 70, the alternating power line 57 of the adapter 20 at the port X2 is electrically connected to the first connector 60, and the first connector 60 at the port X2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits an alternating electric signal to the electrode sheet 13 electrically connected to the port X2 of the adapter 20 One end of the fourth power switch 40-4 is electrically connected to the AC signal generator 39 through the AC power cord 41 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 4 for transmitting alternating electric signals in the second connector 70 through an AC power cord 41-4 and is electrically connected to the alternating power cord 57 at the port Y2 of the adapter 20 through the conductor 4 of the second connector 70, the alternating power cord 57 at the port Y2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits an alternating electric signal to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20.

[0096] The following will refer to Figures 4 to 7 The working principle of the tumor electric field treatment system 100 of this embodiment is described in detail.

[0097] The electromagnetic control switch 162 in the rectifier switching module 16 is a normally closed switch, that is, the third end 3 of the electromagnetic control switch 162 is connected to the first end 1 by default and connected to each temperature sensor 35 of the corresponding row group. The electromagnetic control switch 162 is linked with the corresponding two-way switch 55. When the corresponding two-way switch 55 is switched to its collection end 1, the electromagnetic control switch 162 is also switched to make its third end 3 connected to the first end 1, so as to connect the temperature sensor 35 located in the same row group to the corresponding dual-purpose signal line 19, disconnect the connection between the electrode unit 33 in the corresponding row group and the corresponding dual-purpose signal line 19, and The corresponding control switches 54 are closed in sequence to obtain the analog temperature signal detected by the corresponding temperature sensor 35; when the corresponding bidirectional switching switch 55 is switched to its input terminal 2, the AC signal will trigger the electromagnetic control switch 162 after passing through the rectifier bridge 161, and the electromagnetic control switch 162 is also switched to make its third end 3 and its second end 2 conductive, so as to connect the electrode units 33 located in the same row group to the corresponding dual-purpose signal line 19, disconnect the temperature sensor 35 in the corresponding row group from the corresponding dual-purpose signal line 19, and disconnect all the control switches 54 to transmit the AC signal to the corresponding electrode unit 33.

[0098] Specifically, when it is necessary to detect the temperature of each electrode unit 33 of a certain electrode sheet 13, the second controller 37 of the electric field generator 30 controls the corresponding power switch 40 to disconnect the alternating electric signal applied to the electrode sheet 13, and the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the collection end 1 of each of the multiple bidirectional switching switches 55 of a group of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to be turned on and the input end 2 to be turned off, and the electromagnetic control switch 162 in the rectifier switching module 16 corresponding to each bidirectional switching switch 55 is controlled in linkage. The third end 3 is connected to the first end 1, and the third end 3 is disconnected from the second end 2 to disconnect the alternating electric signal applied to the electrode sheet 13; at the same time, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each control switch 54 in a group of control switches 54 electrically connected to the electrode sheet 13 to be turned on in sequence in time-sharing. At this time, the temperature detection signal of the temperature detection unit 34 corresponding to the electrode unit 33 in the corresponding row group can be collected respectively through multiple detection channels A, B, C, and D of a group of ADC units 52 corresponding to the electrode sheet 13. The above temperature detection signal can be represented by a voltage value. Only one of the five control switches 54 in the group of control switches 54 corresponding to the electrode sheet 13 can be turned on at the same time, and the other four can be turned off. When all the power switches 40 are disconnected and only one of the four bidirectional switching switches 55 of a group of bidirectional switching switches 55 corresponding to the group of ADC units 52 is switched to its collection end 1, and the rest are switched to their input end 2, one of the dual-purpose signal lines 19 of the electrode sheet 13 can be electrically connected to a corresponding detection channel (A, B, C or D) of the ADC unit 52 and turned on. With this arrangement, the group of ADC units 52 can collect the voltage value of the first temperature detection unit 34 in the same row group that is short-circuited with the ground line 18 corresponding to the turned-on control switch 54, or the voltage value of the first and second temperature detection units 34 in series, or the voltage value of the first to third temperature detection units 34 in series, or the voltage value of the first to fourth temperature detection units 34 in series, or the voltage value of the first to fifth temperature detection units 34 in series.

[0099] Specifically, the plurality of bidirectional switches 55 can be switched in sequence so as to sequentially collect the temperatures detected by the temperature detection units 34 corresponding to the electrode units 33 of each row group.

[0100] When it is necessary to collect the temperature detection signal detected by the temperature detection unit 34 corresponding to each electrode unit 33 of the first row group, the second controller 37 of the electric field generator 30 controls the power supply switch 40 corresponding to the electrode sheet 13 to disconnect the alternating electric signal applied to the electrode sheet 13, and controls the first bidirectional switching switch 55-1 to switch to its collection end 1, and the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3 and the fourth bidirectional switching switch 55-4 are all switched to their respective input ends 2, and at the same time, the electromagnetic control switch 162 in the rectifier switching module 16 corresponding to the first bidirectional switching switch 55-1 is controlled to switch to a state where its third end 3 is connected to the first end 1, and the third end 3 of the electromagnetic control switch 162 in each rectifier switching module 16 corresponding to the second bidirectional switching switch 55-2 to the fourth bidirectional switching switch 55-4 is connected to its second end 2. Next, the plurality of control switches 54 are controlled to be closed separately in sequence. Specifically, the control switch 54-1 is first closed, and the control switches 54-2, 54-3, 54-4 and 54-5 are all opened. The temperature detection unit 34 corresponding to the electrode unit 33-1 is powered on, and the temperature detection units 34 corresponding to the remaining electrode units 33 are powered off. The signal end 34-1 of the temperature detection unit 34 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A in the group of ADC units 52. Since only the signal end 34-1 of the temperature detection unit 34 corresponding to the electrode unit 33-1 is connected to the ground, the signal end 34-1 of the temperature detection unit 34 corresponding to the electrode unit 33-1 in the same row group is connected to the ground. The ground terminal 34-2 of the temperature detection unit 34 is disconnected, and each temperature detection unit 34 is provided with a diode 36 connected in series with the temperature sensor 35, which can prevent the current from reversing and ensure that the temperature detection units 34 corresponding to the remaining electrode units 33 will not affect the resistance value of the temperature detection unit 34 corresponding to the electrode unit 33-1. Therefore, only the temperature detection unit 34 corresponding to the electrode unit 33-1 on the first detection channel A of the group of ADC units 52 is effectively operating, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 34 corresponding to the electrode unit 33-1. At this time, the accurate collection of the temperature detection signal at the electrode unit 33-1 is completed.

[0101] Then, the control switch 54-2 is closed, and the control switches 54-1, 54-3, 54-4 and 5 are disconnected. The temperature detection units 34 corresponding to the electrode units 33-1 and 33-2 are connected in series and powered on. The temperature detection units 34 corresponding to the remaining electrode units 33 are powered off. The signal end 34-1 of the temperature detection unit 34 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A in the group of ADC units 52. Since only the ground end 34-2 of the temperature detection unit 34 corresponding to the electrode unit 33-2 is connected to the ground, the ground ends 34-2 of the temperature detection units 34 corresponding to the electrode units 33-3 to 33-5 in the same row group are disconnected, and each temperature detection unit 34 has a signal end corresponding to the temperature detection unit 34. The sensor 35 is connected in series with the corresponding diode 36 to prevent the current from reversing, ensuring that the temperature detection units 34 of the remaining electrode units 33 will not affect the resistance of the temperature detection units 34 corresponding to the electrode units 33-1 and 33-2. Therefore, only the temperature detection units 34 corresponding to the electrode units 33-1 and 33-2 on the first detection channel A of the group of ADC units 52 are effectively operated. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the combined voltage value of the temperature detection units 34 corresponding to the electrode units 33-1 and 33-2 (that is, the combined voltage value is the combined voltage value of the temperature detection unit 34 corresponding to the electrode unit 33-1 and the temperature detection unit 34 corresponding to the electrode unit 33-2). The voltage value of the electrode unit 33-2 can be obtained by subtracting the voltage value of the electrode unit 33-1 from the combined voltage value. Similarly, when only the control switch 54-3 is closed and the other control switches 54 are disconnected, the temperature detection signal (voltage value) collected by the first detection channel A is the combined voltage value of the temperature detection units 34 corresponding to the electrode units 33-1 to 33-3; when only the control switch 54-4 is closed and the other control switches 54 are disconnected, the temperature detection signal (voltage value) collected by the first detection channel A is the combined voltage value of the temperature detection units 34 corresponding to the electrode units 33-1 to 33-4; when only the control switch 54-5 is closed and the other control switches 54 are disconnected, the temperature detection signal (voltage value) collected by the first detection channel A is the combined voltage value of the temperature detection units 34 corresponding to the electrode units 33-1 to 33-5. After collecting the voltage value or combined voltage value detected by the temperature detection unit 34 of each electrode unit 33 of the first row group, the temperature detection signal corresponding to each electrode unit 33 in the first row group can be obtained by simple subtraction conversion.

[0102] Similarly, when it is necessary to collect the temperature detection signal detected by the temperature detection unit 34 corresponding to the electrode unit 33 of the second row group, the second controller 37 of the electric field generator 30 controls the power supply switch 40 corresponding to the electrode sheet 13 to disconnect the alternating electric signal applied to the electrode sheet 13, and the second bidirectional switching switch 55-2 is switched to its collection end 1, and the remaining bidirectional switching switches 55 are all switched to their respective input ends 2, and the electromagnetic control switch 162 in the rectifier switching module 16 corresponding to the second bidirectional switching switch 55-2 is controlled to switch to a conductive state between its third end and the first end, and the electromagnetic control switches 162 of each rectifier switching module 16 corresponding to the remaining row groups are switched to a conductive state between its third end and the second end, and one of the multiple control switches 54 is controlled to be closed in turn. At this time, only the second detection channel B in the group of ADC units 52 is turned on and the voltage value or combined voltage value of the temperature detection unit 34 corresponding to each electrode unit 33 of the second row group can be successively collected, thereby obtaining the temperature detection signal corresponding to each electrode unit 33 of the second row group.

[0103] The control logic for collecting the temperature detection signals detected by the temperature detection units 34 corresponding to the electrode units 33 of the third row group and the fourth row group is similar to the control logic of the first row group or the second row group.

[0104] Thus, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can realize the collection of the temperature detection signals of the temperature detection units 34 corresponding to all the electrode units 33 of the electrode sheet 13 by controlling a group of bidirectional switching switches 55 and a group of control switches 54 electrically connected to a certain electrode sheet 13, and the rectifier switching modules 16 corresponding to and linked to the group of bidirectional switching switches 55. That is, the bidirectional switching unit (unnumbered) is configured to switch the dual-purpose signal line 19 of the corresponding row group to the corresponding temperature sampling point (unnumbered) and simultaneously control the corresponding rectifier switching module 16 in linkage, and by configuring the switch state of the control switch 54 of the corresponding column group, the temperature detection signal of a single temperature detection unit 34 or the combined temperature detection signal of multiple temperature detection units 34 can be obtained. Similarly, the temperature detection signals of the temperature detection units 34 of each electrode unit 33 of other electrode sheets 13 can be obtained.

[0105] The first controller 51 or the second controller 37, the multiple groups of ADC units 52 and the multiple groups of bidirectional switches 55 can automatically perform operations through pre-programmed program codes. For example, the first controller 51 or the second controller 37 first controls the first bidirectional switch 55-1 in the corresponding group of bidirectional switches 55 to switch to the acquisition terminal 1 so that the acquisition terminal 1 is turned on and the input terminal 2 is disconnected, and the remaining bidirectional switches 55 are all switched to their respective input terminals 2, and at the same time, the third end of the electromagnetic control switch 162 in the corresponding rectifier switching module 16 is controlled to be turned on with the first end and the third end is disconnected with the second end, and then the control switches 54-1 to 54-5 are closed in sequence. Similarly, the switching of the second bidirectional switch 55-2, the third bidirectional switch 55-3 and the fourth bidirectional switch 55-4 can be controlled, and the temperature detection signals of all the temperature detection units 34 on at least one pair of electrode sheets 13 are obtained through this operation.

[0106] Therefore, in the embodiment of the present application, by cooperating with the control switch 54, the bidirectional switching switch 55 and the electromagnetic control switch 162 in the rectifier switching module 16, the temperature detection at each electrode unit 33 can be achieved without mutual interference and with high detection accuracy.

[0107] Specifically, when it is necessary to apply an alternating electric signal to each electrode unit 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls a group of control switches 54 electrically connected to the electrode sheet 13 to be completely disconnected; controls the input end 2 of each of the multiple bidirectional switching switches 55 of a group of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to be turned on and the collection end 1 to be disconnected; at the same time, the third end and the second end of the electromagnetic control switch 162 of each corresponding rectifier switching module 16 are controlled to be turned on, and the third end and the first end are disconnected; and the second controller 37 of the electric field generator 30 controls a power supply switch 40 electrically connected to the electrode sheet 13 to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply an alternating electric signal to each electrode unit 33 of the electrode sheet 13 through the alternating power line 57, and the voltage or current of the applied alternating electric signal is adjustable. That is, the bidirectional switching unit (not numbered) is configured to switch the dual-purpose signal lines 19 corresponding to at least two row groups to be connected to the alternating power line 57 at the same time, so that the electrode units 33 of at least two row groups are simultaneously applied with alternating electrical signals based on the alternating power line 57. Among them, since the multiple electrode units 33 of each row group are connected in parallel, when the alternating electrical signals are applied to the electrode units 33 of the electrode sheet 3, the alternating electrical signals are simultaneously applied to the multiple electrode units 33 in one row group. In other embodiments, the alternating electrical signals can also be simultaneously applied to the electrode units 33 of two or three row groups in the same time period, which will not be described in detail here.

[0108] It should be noted that the control switch 54 electrically connected to the multi-way grounding wires 18 of the electrode sheet 13 and the bidirectional switch 55 electrically connected to the multi-way dual-purpose signal wires 19 of the electrode sheet 13 in the embodiment of the present application are both provided in the adapter 20, but in other embodiments, the control switch 54 electrically connected to the grounding wire 18 and the bidirectional switch 55 electrically connected to the dual-purpose signal wire 19 can also be provided on the electrode sheet 13 or provided in the electric field generator 30, which will not be described in detail here. In addition, the ADC unit 52 provided in the adapter 20 can also be provided in the electric field generator 30 and directly controlled by the second controller 37.

[0109] The tumor electric field therapy system 100 of the present application can realize real-time, comprehensive and accurate monitoring of the temperature of all electrode units 33 on the electrode sheet 13 without adding the core of the first cable 15 electrically connected to the electrode sheet 13, and then determine whether the electrode sheet 13 is qualified according to the obtained temperature detection signal; or determine whether the temperature detection unit 34 of the electrode sheet 13 is faulty or abnormal according to the obtained temperature detection signal, and determine whether the electrode sheet 13 needs to be replaced based on the number of faulty or abnormal temperature detection units 34 obtained; or if the electrode sheet is qualified, the type of electrode sheet can be identified according to the obtained temperature detection signal; or if the electrode sheet is qualified, the electrode unit 33 of the electrode sheet 13 can be determined according to the obtained temperature detection signal whether it is over-temperature, and then control the alternating electric signal applied to the electrode sheet 13 or the electrode unit 33 of the corresponding row group of the electrode sheet 13, so as to avoid low-temperature burns on the patient's body surface when the tumor is treated by the electrode sheet 13. In addition, the substrate 31 of the electrode sheet 13 of the present application is electrically connected to the same electrode unit 33 and the signal end 34-1 of the corresponding temperature detection unit 34 through the same dual-purpose signal line 19. While it can transmit the alternating electric signal in the first mode and transmit the direct current signal for temperature signal collection and the collected temperature detection signal in the second mode through the dual-purpose signal line 19, it also greatly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) arranged thereon, reduces the wiring difficulty of the substrate 31, simplifies the manufacturing process, reduces the weight of the substrate 31, and reduces the manufacturing cost. The electrode sheet 13 of the present application can also switch between applying an alternating electric signal for tumor treatment and transmitting a direct current signal for temperature collection and transmitting the collected temperature detection signal through the combined control of a control switch 54 electrically connected to the grounding line 18 arranged thereon, a bidirectional switching switch 55 electrically connected to the dual-purpose signal line 19, and a rectifier switching module 16 linked to the bidirectional switching switch 55.

[0110] Specifically, when it is necessary to apply an alternating electric signal to the patient through each electrode unit 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls to disconnect all the control switches 54 in a group of control switches 54 corresponding to the electrode sheet 13, and at the same time controls to switch all the bidirectional switching switches 55 in a group of bidirectional switching switches 55 corresponding to the electrode sheet 13 to their respective input ends 2, so that the collection ends 1 of the bidirectional switching switches 55 are all disconnected, the input ends 2 are all turned on, and the first ends of the electromagnetic control switches 161 in the rectifier switching modules 16 corresponding to the bidirectional switching switches 55 are all disconnected from their third ends, and the second ends are all turned on from their third ends, so that each dual-purpose signal line 19 of the electrode sheet 13 is electrically connected to an alternating power line 57 corresponding to the adapter 20 and the electrode sheet 13, thereby transmitting the alternating electric signal to each electrode unit 33 of the electrode sheet 13. When the digital temperature signal corresponding to the temperature detection signal of the temperature detection unit 34 corresponding to all the electrode units 33 of the detected electrode sheet 13 is much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 through its second controller 37 to continue to generate an alternating electric signal with an increased voltage or current amplitude, or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 13 through an alternating power line 57 corresponding to the adapter 20, so that the pair of electrode sheets 13 continue to apply the alternating electric signal; when the digital temperature signal corresponding to the temperature detection signal of the temperature detection unit 34 corresponding to all the electrode units 33 of the detected electrode sheet 13 is lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the voltage or current of the alternating electric signal generated by the AC signal generator 39 through the second controller 37, thereby reducing the voltage of the alternating electric signal applied to the pair of electrode sheets 13. or current; when it is detected that a digital temperature signal corresponding to a temperature detection signal of a temperature detection unit 34 corresponding to an electrode unit 33 of a certain electrode sheet 13 is greater than a preset temperature threshold, the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode sheet 13 to be disconnected through the second controller 37 to stop applying an alternating electric signal to the electrode sheet 13; or the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 controls all the two-way switching switches 55 in a group of two-way switching switches 55 electrically connected to the electrode sheet 13 to switch from their input end 2 to the collection end 1, that is, the collection end 1 of all the two-way switching switches 55 in a group of two-way switching switches 55 electrically connected to the electrode sheet 13 is controlled to be turned on and the input end 2 is turned off, and the first end of the electromagnetic control switch in the rectifier switching module 16 corresponding to each two-way switching switch 55 is turned on and the second end is turned off, thereby stopping applying an alternating electric signal to the electrode sheet 13;Or, when it is detected that a digital temperature signal corresponding to a temperature detection signal of a temperature detection unit 34 corresponding to an electrode unit 33 of a certain electrode sheet 13 is greater than a preset temperature threshold, the second controller 37 of the electric field generator 30 controls the power switch 40 electrically connected to the electrode sheet 13 to continue to be turned on, and the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 controls a bidirectional switch 55 electrically connected to the electrode unit 33 of the electrode sheet 13 to switch from its input end 2 to its collection end 1, and the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 simultaneously controls the bidirectional switch 55 electrically connected to the electrode unit 33 of the electrode sheet 13 to switch from its input end 2 to its collection end 1. The remaining two-way switches 55 electrically connected to the electrode units 33 in different rows from the electrode units 33 whose temperature detection signals exceed the preset temperature threshold, whose digital temperature signals corresponding to the temperature detection signals of the electrode sheet 13 do not exceed the preset temperature threshold, continue to be electrically connected to their respective input terminals 2, so as to stop applying the alternating electric signal to all the electrode units 33 in the row where the electrode units 33 whose digital temperature signals corresponding to the temperature detection signals of the electrode sheet 13 exceed the preset temperature threshold are located, and continue to apply the alternating electric signal to the electrode units 33 in the remaining rows where the digital temperature signals corresponding to the temperature detection signals of the electrode sheet 13 do not exceed the preset temperature threshold. Thus, the alternating electric signal application control method based on the temperature detection signal of the tumor electric field treatment system 100 is realized. ;

[0111] Another tumor electric field treatment system is described below. Fig. 9 The embodiment shown in the figure shows a schematic diagram of the circuit connection between the electrode sheet 13A and the aforementioned adapter 20 in the tumor electric field treatment system. The main concept of the tumor electric field treatment system is Figure 4 The tumor electric field treatment system 100 of the embodiment is the same, the electrode sheet 13A is electrically connected to the adapter 20 through the first connector 60 with 10 core wires, and also includes a substrate 31A, a plurality of electrode units 33A, 33-1A-33-19A distributed on the substrate 31A and provided with through holes 331A, a temperature detection unit 34A corresponding to each electrode unit 33A, a plurality of rectifier switching modules 16A provided on the substrate 31A, and a plurality of dual-purpose signal lines embedded on the substrate 31A 19A, 19-1A to 19-4A, ground wires 18A, 18-1A to 18-5A, rectifier ground wire (unnumbered), the rectifier switching module 16 also includes a rectifier bridge 161A, an electromagnetic control switch 162A and a voltage regulator tube 163A, the difference is that: each electrode sheet 13A in the electrode sheet 13A of the tumor electric field treatment system includes 19 electrode units 33A, and the number of electrode units 33A contained in each row group and each column group of each electrode sheet 13A is different. For example, the 19 electrode units 33A of each electrode sheet 13A are divided into four row groups and five column groups, each of the first three row groups has 5 electrode units 33A, and the fourth row group has 4 electrode units 33A.

[0112] Among them, other contents of this embodiment, such as the temperature detection method of the electrode sheet 13A, the alternating electric signal application control method, etc., are similar to the contents of the above-mentioned tumor electric field treatment system 100 and will not be repeated here.

[0113] Several other tumor electric field therapy systems 100", 100"', 100"" are described below. In these examples, the tumor electric field therapy systems 100", 100"', 100"" each include four electrode sheets 13", 13"', 13"", adapters 20A, 20B electrically connected to the electrode sheets 13", 13"', 13"" and an electric field generator 30 electrically connected to the adapters 20A, 20B. Each electrode sheet 13", 13"', 13"" includes 13 electrode units 33", 33"', 33"", respectively. The connection method between the 13 electrode units 33", 33"', 33"" is different from that of the electrode units 33", 33"', 33"" at the free ends.

[0114] Specific reference Fig.10 As shown, each electrode sheet 13" of the tumor electric field treatment system 100" includes 13 electrode units 33", each electrode sheet 13" does not have an electrode unit 33" at a free end, and the number of electrode units 33" contained in each row group and each column group of each electrode sheet 13" is different. Specifically, these 13 electrode units 33" are arranged in five row groups and five column groups in a spatial structure. Each of the first row and the fifth row includes two electrode units 33", and the two electrode units 33" of each row are respectively located on the second column and the fourth column; each of the second row to the fourth row includes three electrode units 33", and the three electrode units 33" of each row are respectively located on the first column, the third column and the fifth column. In each of the above five rows of electrode units 33", two adjacent electrode units 33" are connected by a connecting belt (unnumbered). In each of the first column, the third column and the fifth column, two adjacent electrode units 33" are connected by a connecting belt (unnumbered). The electrode unit 33" located in the first row and the second column is connected to the electrode unit 33" located in the second row and the first column and the second row and the third column respectively through a connecting belt (unnumbered); the electrode unit 33" located in the first row and the fourth column is connected to the electrode unit 33" located in the second row and the third column and the second row and the fifth column respectively through a connecting belt (unnumbered); the electrode unit 33" located in the fifth row and the second column is connected to the electrode unit 33" located in the fourth row and the first column and the fourth row and the third column respectively through a connecting belt (unnumbered); the electrode unit 33" located in the fifth row and the fourth column is connected to the electrode unit 33" located in the fourth row and the third column and the fourth row and the fifth column respectively through a connecting belt (unnumbered).

[0115] Continue to refer Fig.11As shown, the arrangement of the electrode units 33"' in the electrode sheet 13"' of the tumor electric field treatment system 100"' is the same as the electrode units 33" in the tumor electric field treatment system 100", with the difference that: no connecting belt is provided between the electrode unit 33"' located in the first row and second column and the two electrode units 33"' located in the first row and fourth column and the second row and first column; no connecting belt is provided between the electrode unit 33"' located in the fifth row and fourth column and the two electrode units 33"' located in the fifth row and second column and the fourth row and fifth column; no connecting belt is provided between the two electrode units 33"' located in the second row and fifth column and the third row and fifth column; no connecting belt is provided between the two electrode units 33"' located in the third row and first column and the fourth row and first column. The connecting belt (not shown) of the electrode sheet 100"' is provided in this way to form a corresponding open space and free end for easy application.

[0116] Continue to refer Fig.12 As shown, the main concept of the tumor electric field treatment system 100"" is the same as the above-mentioned tumor electric field treatment system 100"", with the difference that: the 13 electrode units 33"" in each electrode sheet 13"" of the tumor electric field treatment system 100"" are connected by 18 connecting strips (unnumbered). Specifically, no connecting strip is set between two adjacent electrode units 33"" in the first row and each of the fifth rows; no connecting strip is set between two electrode units 33"" in the first column of the second row and the third column of the second row; no connecting strip is set between two electrode units 33"" in the third column of the fourth row and the fifth column of the fourth row. The connecting strips (not shown) of the electrode sheet 100"" are set in this way to form corresponding open spaces and free ends for easy application.

[0117] The circuit connection diagram of the electrode sheets 13", 13"', 13"" and the adapters 20A, 20B in the above-mentioned tumor electric field treatment system 100", 100"', 100"" can be referred to Fig.13 , Fig.15 , Fig.16 The circuit connection diagram shown in any one of the following. Fig.13As shown, it shows a schematic diagram of the circuit connection between the electrode sheet 13B and the adapter 20A in the tumor electric field treatment system, wherein the 13 electrode units 33B, 33-1B to 33-13B of each electrode sheet 13B are divided into three row groups and five column groups, each of the first two row groups has 5 electrode units 33B, and the third row group has 3 electrode units 33B. Each electrode sheet 13B includes three rectifier switching modules 16B, which correspond to the three row groups one by one. Each electrode unit 33B is also provided with a perforation 331B, and each corresponds to a temperature detection unit 34B. The substrate 31B of the electrode sheet 13B is also embedded with dual-purpose signal lines 19B, 19-1B to 19-3B that correspond to the three row groups of the electrode unit 33B and are electrically connected to the corresponding rectifier switching module 16B, grounding lines 18B, 18-1B to 18-5B that correspond to the five column groups of the electrode unit 33B, and a rectifier ground line (unnumbered) that grounds each rectifier switching module 16B. Each rectifier switching module 16B also includes the aforementioned rectifier bridge 161B, electromagnetic control switch 162B and voltage regulator tube 163B. The electrode sheet 13B is electrically connected to the adapter 20A through a first connector 60A with a 9-core wire. The adapter 20A is connected to the electric field generator 30A through a second connector 70A.

[0118] Combination Fig.14 , which shows a schematic diagram of the internal structure of the adapter 20A adapted to the electrode sheet 13B. The adapter 20A includes a first controller 51A, an ADC unit 52A, a first power module 58A, a first communication unit 56A, four groups of two-way switching switches 55A and four groups of control switches 54A corresponding to four electrode sheets 13B, four groups of voltage-dividing resistors 53A corresponding to the four groups of two-way switching switches 55A, and AC power lines 57A corresponding to four electrode sheets 13B, each group of two-way switching switches 55A includes three two-way switching switches 55A, 55-1A to 55-3A, corresponding to three row groups of each electrode sheet 13B, and each group of control switches 54A includes five control switches 54A, 54-1A to 54-5A, corresponding to five column groups of each electrode sheet 13B. Each group of voltage dividers 53A, R1 to R12 includes three voltage divider resistors R1 - R3 , R4 - R6 , R7 - R9 , and R10 - R12 that correspond one-to-one to the corresponding group of bidirectional switches 55 - 1A to 55 - 3A.

[0119] Continue to refer Fig.15As shown, it shows a schematic diagram of the circuit connection between the electrode sheet 13C and the adapter 20B in the tumor electric field treatment system, wherein the 13 electrode units 33C, 33-1C to 33-13C in each electrode sheet 13C can also be divided into four row groups and four column groups, each of the first three row groups has 4 electrode units 33C, and the fourth row group has 1 electrode unit 33C. The electrode sheet 13C includes four rectifier switching modules 16C, which correspond to the four row groups one by one. Each electrode unit 33C is also correspondingly provided with a temperature detection unit 34C. The substrate 31C of the electrode sheet 13C is also embedded with dual-purpose signal lines 19C, 19-1C to 19-4C that correspond one-to-one to the four row groups of the electrode unit 33C and are electrically connected to the corresponding rectifier switching modules 16C, grounding lines 18C, 18-1C to 18-4C that correspond one-to-one to the four column groups of the electrode unit 33C, and a rectifier ground line (unnumbered) that grounds each rectifier switching module 16C. Each rectifier switching module 16C also includes the aforementioned rectifier bridge 161C, electromagnetic control switch 162C and voltage regulator tube 163C. The electrode sheet 13C is electrically connected to the adapter 20B via a first connector 60B having a 9-core wire. The adapter 20B is connected to the electric field generator 30 via a second connector 70B. Fig.16 As shown, it shows the electrode sheet 13D and the Fig.15 The circuit connection diagram of the adapter 20B shown in FIG. 1 is a schematic diagram of the circuit connection of the adapter 20B, wherein the 13 electrode units 33D, 33-1D to 33-13D of the electrode sheet 13D can also be divided into four row groups and four column groups, the first row group has four electrode units 33D, and each row group in the second to fourth row groups has three electrode units 33D. The electrode sheet 13D also includes four rectifier switching modules 16D, which correspond to the four row groups one by one. Each electrode unit 33D is also provided with a temperature detection unit 34D. The substrate 31D of the electrode sheet 13D is also embedded with dual-purpose signal lines 19D, 19-1D to 19-4D corresponding to the four row groups of the electrode unit 33D, grounding lines 18D, 18-1D to 18-4D corresponding to the four column groups of the electrode unit 33D, and a rectifier ground line (not numbered) that grounds each rectifier switching module 16D. Each rectifier switching module 16D also includes a rectifier bridge 161D, an electromagnetic control switch 162D, and a voltage regulator tube 163D. The electrode sheet 13D is electrically connected to the adapter 20B via a first connector 60B having a 9-core wire. The adapter 20B is connected to the electric field generator 30 via a second connector 70B. Combined Fig.17, which shows a schematic diagram of the internal structure of the adapter 20B adapted to the electrode sheets 13C and 13D. The adapter 20B includes a first controller 51B, an ADC unit 52B, a first power module 58B, a first communication unit 56B, four groups of two-way switching switches 55B and four groups of control switches 54B corresponding to the four electrode sheets 13C and 13D, four groups of voltage-dividing resistors 53B, R1 to R16 corresponding to the four groups of two-way switching switches 55B, and an AC power line 57B corresponding to the corresponding electrode sheets 13C and 13D, each group of two-way switching switches 55B includes four two-way switching switches 55B, 55-1B to 55-4B, corresponding to the four row groups of each electrode sheet 13C and 13D, and each group of control switches 54B includes four control switches 54B, 54-1B to 54-4B, corresponding to the four column groups of each electrode sheet 13C and 13D. Each group of voltage dividing resistors 53B includes voltage dividing resistors R1-R4, R5-R8, R9-R12, and R13-R16 which correspond one-to-one to the four bidirectional switches 55-1B to 55-4B in the corresponding group.

[0120] Among them, other contents in these embodiments, such as the temperature detection method of the electrode sheets 13B, 13C, and 13D, the alternating electric signal application control method, etc., are similar to the contents of the above-mentioned tumor electric field treatment system 100 and will not be repeated here.

[0121] Several other tumor electric field treatment systems are described below. In these examples, each electrode sheet 13E, 13F, and 13G includes 12 electrode units 33E, 33-1E to 33-12E, 33F, 33-1F to 33-12F, 33G, 33-1G to 33-12G, respectively. The connection method between the 12 electrode units 33E, 33-1E to 33-12E, 33F, 33-1F to 33-12F, 33G, 33-1G to 33-12G and the electrode units 33E, 33F, and 33G at the free ends may be different.

[0122] For the case where each electrode sheet 13E, 13F, 13G includes 12 electrode units 33E, 33-1E to 33-12E, 33F, 33-1F to 33-12F, 33G, 33-1G to 33-12G, as shown in FIG. Fig.18 As shown, it shows the electrode sheet 13E and the Fig.13The circuit connection diagram of the adapter 20A shown in the figure, the 12 electrode units 33E, 33-1E to 33-12E of each electrode sheet 13E in the tumor electric field treatment system are divided into three row groups and five column groups, each of the first two row groups has 5 electrode units 33E, and the third row group has 2 electrode units 33E. Each electrode unit 33E is also correspondingly provided with a temperature detection unit 34E. Each electrode sheet 13E includes three rectifier switching modules 16E, which correspond to the three row groups one by one. The rectifier switching module 16E also has a rectifier bridge 161E, an electromagnetic control switch 162E and a voltage regulator tube 163E. The substrate 31E of each electrode sheet 13E is also embedded with dual-purpose signal lines 19E, 19-1E to 19-3E corresponding to the three row groups of the electrode unit 33E and electrically connected to the corresponding rectifier switching module 16E, grounding lines 18E, 18-1E to 18-5E corresponding to the five column groups of the electrode unit 33E, and a rectifier ground line (unnumbered) connecting each rectifier switching module 16E to the ground. Each set of bidirectional switches 55A of the adapter 20A includes three bidirectional switches 55A, 55-1A to 55-3A, corresponding to the three row groups of each electrode sheet 13E, and each set of control switches 54A of the adapter 20A includes five control switches 54A, 54-1A to 54-4A, corresponding to the five column groups of each electrode sheet 13E. Each group of voltage divider resistors 53A of the adapter 20A includes three voltage divider resistors R1-R3, R4-R6, R7-R9, R10-R12 corresponding to the three bidirectional switches 55A in the corresponding group. Each electrode sheet 13E is connected to the adapter 20A via a first connector 60A having 9-core wires.

[0123] like Fig.19 As shown, it shows a circuit connection diagram of the electrode sheet 13F and the adapter 20C in the tumor electric field treatment system, wherein the 13 electrode units 33F, 33-1F to 33-12F can also be divided into three row groups and four column groups, and each row group has 4 electrode units 33F. Each electrode unit 33F is also correspondingly provided with a temperature detection unit 34F. Each electrode sheet 13F includes three rectifier switching modules 16F, which correspond to the three row groups one by one. Each rectifier switching module 16F also has a rectifier bridge 161F, an electromagnetic control switch 162F and a voltage regulator tube 163F. The substrate 31F of each electrode sheet 13F is also embedded with dual-purpose signal lines 19F, 19-1F to 19-3F corresponding to the three row groups of the electrode unit 33F, grounding lines 18F, 18-1F to 18-4F corresponding to the four column groups of the electrode unit 33F, and a rectifier ground line (not numbered) for grounding each rectifier switching module 16F. Fig. 20, which shows a schematic diagram of the internal structure of the adapter 20C adapted to the electrode sheet 13F. The adapter 20C includes a first controller 51C, an ADC unit 52C, a first power module 58C, a first communication unit 56C, four groups of two-way switching switches 55C corresponding to four electrode sheets 13F and four groups of control switches 54C, four groups of voltage-dividing resistors 53C, R1-R3, R4-R6, R7-R9, R10-R12 corresponding to the four groups of two-way switching switches 55C, and alternating power lines 57C electrically connected to the corresponding electrode sheets 13F. Each group of two-way switching switches 55C includes three two-way switching switches 55C, 55-1C to 55-3C, which correspond to the three row groups of each electrode sheet 13F. Each group of control switches 54C includes four control switches 54C, 54-1C to 54-4C, which correspond to the four column groups of each electrode sheet 13F. Each electrode sheet 13F is electrically connected to the adapter 20C via a corresponding first connector 60C having an 8-core wire, and the adapter 20C is electrically connected to the electric field generator 30, 30A via a second connector 70C.

[0124] like Fig.21 As shown, it shows a schematic diagram of the circuit connection between the electrode sheet 13G and the adapter 20D in the tumor electric field treatment system, wherein the 13 electrode units 33G, 33-1G to 33-12G can also be divided into four row groups and three column groups, each row group having three electrode units 33G. The electrode sheet 13G includes four rectifier switching modules 16G, which correspond to the four row groups one by one. Each electrode unit 33G is provided with a temperature detection unit 34G. The substrate 31G of the electrode sheet 13G is also embedded with dual-purpose signal lines 19G, 19-1G to 19-4G, which correspond to the four row groups of the electrode units 33G one by one and are electrically connected to the corresponding rectifier switching modules 16G, grounding lines 18G, 18-1G to 18-3G, which correspond to the three column groups of the electrode units 33G one by one, and rectifier ground lines (unnumbered) that connect each rectifier switching module 16G to ground. Each rectifier switching module 16G also includes a rectifier bridge 161G, an electromagnetic control switch 162G and a voltage regulator tube 163G. Each electrode sheet 13G is connected to the adapter 20D through a first connector 60D having an 8-core wire. Fig. 22, which shows a schematic diagram of the internal structure of the adapter 20D adapted to the electrode sheet 13G. The adapter 20D includes a first controller 51D, an ADC unit 52D, a first power module 58D, a first communication unit 56D, four groups of bidirectional switches 55D and four groups of control switches 54D corresponding to the four electrode sheets 13G, four groups of voltage transformers 53D corresponding to the four groups of bidirectional switches 55D, and four alternating power lines 57D corresponding to the four electrode sheets 13G. Each group of bidirectional switches 55D includes four bidirectional switches 55D, 55-1D to 55-4D, which correspond to the four row groups of each electrode sheet 13G. Each group of control switches 54D includes three control switches 54D, 54-1D to 54-3D, which correspond to the three column groups of each electrode sheet 13D. Each set of voltage dividing resistors 53D includes four voltage dividing resistors R1-R4, R5-R8, R9-R12, and R13-R16. The adapter 20D is connected to the electric field generator 30 via a second connector 70D.

[0125] Among them, other contents in these embodiments, such as the temperature detection method of the electrode sheets 13E, 13F, and 13G, the alternating electric signal application control method, etc., are similar to the contents of the above-mentioned tumor electric field treatment system 100 and will not be repeated here.

[0126] Another tumor electric field treatment system 100""' is described below. In this example, each electrode sheet 13""' includes 9 electrode units 33""'. The connection between the 9 electrode units 33""' and the electrode units 33""' at the free ends are as follows: Fig.23 shown.

[0127] The circuit connection diagrams of the electrode sheet 13'' and the adapters 20C and 20E in the above-mentioned tumor electric field treatment system 100''' can be referred to respectively. Fig.24 , Fig.25 Schematic diagram of circuit connection in . Specifically, Fig.24 As shown, it shows the electrode sheet 13H and the Fig. 20, wherein the 9 electrode units 33H, 33-1H to 33-9H of each electrode sheet 13H in the tumor electric field treatment system are divided into three row groups and four column groups, each of the first two row groups has 4 electrode units 33H, and the third row group has 1 electrode unit 33H. The electrode sheet 13H includes three rectifier switching modules 16H, which correspond to the three row groups one by one. The connecting plate 31H of the electrode sheet 13H is embedded with dual-purpose signal lines 19H, 19-1H to 19-3H corresponding to the three row groups of the electrode units 33H and electrically connected to the corresponding rectifier switching modules 16H, grounding lines 18H, 18-1H to 18-4H corresponding to the four column groups of the electrode units 33H, and a rectifier ground line (unnumbered) for grounding all the rectifier switching modules 16H. Each rectifier switching module 16H also includes a rectifier bridge 161H, an electromagnetic control switch 162H and a voltage regulator tube 163H. Each electrode sheet 13H is electrically connected to the adapter 20C through a first connector 60C having an 8-core wire. Each group of bidirectional switching switches 55C of the adapter 20C includes three bidirectional switching switches 55C, 55-1C to 55-3C, which correspond to the three row groups of each electrode sheet 13H respectively, and each group of control switches 54C includes four control switches 54C, 54-1C to 54-4C, which correspond to the four column groups of each electrode sheet 13H respectively.

[0128] like Fig.25 The embodiment shown shows a schematic diagram of the circuit connection between the electrode sheet 13I and the adapter 20E in the tumor electric field treatment system, wherein the 9 electrode units 33I, 33-1I to 33-9I of each electrode sheet 13I in the tumor electric field treatment system can also be divided into three row groups and three column groups, and each row group has 3 electrode units 33I. Each electrode unit 33I is provided with a temperature detection unit 34I. The electrode sheet 13I includes three rectifier switching modules 16I, which correspond to the three row groups one by one, respectively. The substrate 31I of the electrode sheet 13I is embedded with dual-purpose signal lines 19, 19-1I to 19-3I, which correspond to the three row groups of the electrode units 33I and are electrically connected to the corresponding rectifier switching modules 16I, grounding lines 18I, 18-1I to 18-3I, which correspond to the three column groups of the electrode units 33I, and a rectifier ground line (not numbered) that grounds all the rectifier switching modules 16I. Each rectifier switching module 16I also includes a rectifier bridge 161I, an electromagnetic control switch 162I and a voltage regulator tube 163I. Each electrode sheet 13I is electrically connected to the adapter 20E through a first connector 60E having a 7-core wire. Fig.26The adapter 20E includes a first controller 51E, an ADC unit 52E, a first power module 58E, a first communication unit 56E, four groups of bidirectional switches 55E and four groups of control switches 54E corresponding to the four electrode sheets 13I, four groups of voltage transformers 53E, R1-R3, R4-R6, R7-R9, R10-R12 corresponding to the four groups of bidirectional switches 55E, and four alternating power lines 57E corresponding to the four electrode sheets 13I. Each group of bidirectional switches 55E includes three bidirectional switches 55-1E to 55-3E, which correspond to the three row groups of each electrode sheet 13I, and each group of control switches 54E includes three control switches 54-1E to 54-3E, which correspond to the three column groups of each electrode sheet 13I. Each group of voltage-dividing resistors 53E has three voltage-dividing resistors R1 - R3 , R4 - R6 , R7 - R9 , and R10 - R12 that correspond one-to-one to the corresponding group of bidirectional switches 55 - 1E to 55 - 3E.

[0129] Among them, other contents in these embodiments, such as the temperature detection method of the electrode sheets 13H and 13I, the alternating electric signal application control method, etc. are similar to the contents of the above-mentioned tumor electric field treatment system 100 and will not be repeated here.

[0130] The present application embodiment provides an electrode sheet temperature detection method, which is applied to each of the above-mentioned tumor electric field treatment systems. The following takes the tumor electric field treatment system 100 as an example. Fig. 27 As shown, it includes the following steps:

[0131] Step 210: Control the bidirectional switching unit so that the dual-purpose signal line 19 corresponding to at least one row group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point, wherein the first end of the rectifier switching module 16 corresponding to the row group in the corresponding electrode sheet 13 is connected to the third end.

[0132] Specifically, the power supply switch 40, the bidirectional switching switch 55 electrically connected to the electrode units 33 of the electrode sheet 13, and the rectifying switching module 16 are controlled to disconnect the alternating electric signal applied to the electrode units 33 of the electrode sheet 13, and at the same time connect the direct current signal applied to the signal terminal 34-1 of the temperature detection unit 34 of the electrode unit 33 of the electrode sheet 13.

[0133] Further, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to switch from one end electrically connected to the alternating electrical signal to one end electrically connected to the direct current signal, that is, the bidirectional switching switch 55 electrically connected to the electrode sheet 13 is controlled to switch from its input end 2 to its collection end 1, and the electromagnetic control switch 162 in the rectifier switching module 16 is also controlled to switch from the conductive state between its third end and its second end to the conductive state between its third end and its first end; or, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to switch the electrode unit 33 of each electrode unit 33 of the electrode sheet 13 from the conductive state to the disconnected state and at the same time control the signal end 34-1 of the temperature detection unit 34 of each electrode unit 33 of the electrode sheet 13 to switch from the disconnected state to the conductive state.

[0134] Step 220: Control the control switch 54 corresponding to each column group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0135] Specifically, the control switch 54 electrically connected to the ground terminal 34 - 2 of the temperature detection unit 34 of each electrode unit 33 of the electrode sheet 13 is turned on in a time-sequential manner to obtain the temperature detection signal of the temperature detection unit 34 of each electrode unit 33 of the electrode sheet 13 .

[0136] In some embodiments, when the dual-purpose signal lines 19 corresponding to each row group are respectively connected to the corresponding temperature sampling points, the control switches 54 corresponding to each column group are controlled, including: controlling the control switches 54 corresponding to each column group to close in sequence to respectively sample the analog temperature signals of each electrode unit 33 in each row group.

[0137] The electrode sheet temperature detection method of the present application can quickly and accurately obtain the temperatures of all electrode units of the electrode sheet; and based on the temperature detection signals of all the temperature detection units of the electrode sheet, it can be judged whether the temperature detection units of the electrode sheet are faulty, abnormal, or whether the electrode sheet is qualified or needs to be replaced; it is also possible to judge whether each electrode unit of the electrode sheet is over-temperature based on the temperature detection signals of all the temperature detection units of the electrode sheet when each temperature detection unit of the electrode sheet is normal, and then control the alternating electric signal applied to the electrode sheet or to each electrode unit of the electrode sheet; it is also possible to identify the type of electrode sheet when there is no abnormality in the temperature detection signals of each temperature detection unit of the electrode sheet.

[0138] The embodiment of the present application provides a quality detection method for an electrode sheet, which is applied to a quality detection system for an electrode sheet. Taking the tumor electric field therapy system 100 as an example, the quality detection system for the electrode sheet includes the above-mentioned tumor electric field therapy system 100 and a host computer (not shown), the host computer (not shown) and the tumor electric field therapy system 100 are communicatively connected, specifically, the host computer (not shown) is electrically connected to the adapter 20, and the adapter 20 is used to sample the analog temperature signal detected by each temperature detection unit 34 in the electrode sheet 13, and determine the test code array of the electrode sheet 30 according to the sampled temperature signal detected by each temperature detection unit 34, and send the test code array to the host computer (not shown), so that the host computer (not shown) compares the test code array with the standard code array when the electrode sheet 13 being tested is qualified, and determines whether the electrode sheet 13 is qualified.

[0139] Specifically, refer to Fig.28 As shown, the temperature detection method of the electrode sheet includes the following steps:

[0140] S310 , obtaining the temperature signal detected by each temperature detection unit 34 in the electrode sheet 13 .

[0141] S320 , determining a test code array B of the electrode sheet 13 according to the analog temperature signal detected by each temperature detection unit 34 .

[0142] Specifically, the state of each temperature detection unit 34 is determined according to the analog temperature signal detected by each temperature detection unit 34, and a corresponding code is assigned to determine the test code array of the electrode sheet 13. When the ADC unit 52 obtains a plurality of AD sampling values, it also sends the plurality of AD sampling values ​​to the first controller 51, so that the first controller 51 determines the test code array of the electrode sheet 13 according to the plurality of AD sampling values, and sends it to the host computer (not shown) through the first communication unit 56.

[0143] For example, when the AD sampling value obtained by the ADC unit 52 is greater than 0.5V and less than 3V, the corresponding code is the first code such as 1; when the AD sampling value obtained by the ADC unit 52 is less than or equal to 0.3V, the corresponding code is the third code such as 0; when the AD sampling value obtained by the ADC unit 52 is greater than or equal to 3.1V, the corresponding code is the second code such as 2.

[0144] Therefore, in the corresponding detection positions numbered 1 to 20 of the electrode sheet 13, if the temperature sensor 35 is short-circuited, the corresponding code is the third code such as 0; if the temperature sensor 35 is normal, the corresponding code is the first code such as 1; if there is no temperature sensor 35 or the temperature sensor 35 is short-circuited, the corresponding code is the second code such as 2.

[0145] Take the example of an electrode sheet 13 having 20 electrode units 33, each electrode unit 33 corresponds to a temperature sensor 35, that is, the corresponding detection positions numbered 1 to 20 of the electrode sheet 13 all have temperature sensors 35, and the codes are all 1, and the 20 codes are combined to obtain a 20-bit standard code array of 11111 11111 11111 11111. When the temperature sensor 35 is short-circuited, assuming that the temperature sensor 35 of the detection position numbered 1 is short-circuited, the 20-bit code array obtained is 2111111111111111 11111. When the temperature sensor 35 is short-circuited, assuming that the temperature sensor 35 of the detection position numbered 1 is short-circuited, the 20-bit code array obtained is 01111 11111 11111 11111.

[0146] The test coding array is compared with the standard coding array for consistency to determine whether the electrode sheet 13 is qualified, wherein the standard coding includes at least the first coding and the second coding, the first coding is used to indicate that the temperature detection unit 34 is in a normal state, and the second coding is used to indicate that the temperature detection unit 34 is in an open circuit state or an unset state.

[0147] Optionally, the analog temperature signal is characterized by a voltage value, and a test code array B of the electrode sheet 13 is determined according to the analog temperature signal detected by each temperature detection unit 34, including: determining the voltage range in which the voltage value is located; determining the code corresponding to the corresponding temperature detection unit 34 according to the voltage range in which the voltage value is located, wherein different voltage ranges in which the voltage value is located correspond to different codes (0, 1 or 2); generating the test code array B of the corresponding electrode sheet 13 according to the code (0, 1 or 2) corresponding to each temperature detection unit 34.

[0148] S330, comparing the test code array B with the standard code array A to determine whether the electrode sheet 13 is qualified.

[0149] Optionally, the standard coding array A includes at least the first coding, and the standard coding array A may also include the second coding. The test coding array B includes at least one of the first coding, the second coding and the third coding. Among them, the first coding is used to indicate that the temperature detection unit is in a normal state, the second coding is used to indicate that the temperature detection unit is in an open circuit state or an unset state, and the third coding is used to indicate that the temperature detection unit is in a short circuit state. In this embodiment, the first coding is "1", the second coding is "2", and the third coding is "0".

[0150] Optionally, the quality inspection system of the electrode sheet may further include an alarm and a display, the alarm is connected to a host computer (not shown), the display is connected to the host computer, and after comparing the test code array B with the standard code array A to determine whether the electrode sheet 13 is qualified, the method further includes: displaying the test code array B of the electrode sheet 13, the standard code array A, and whether the electrode sheet 13 is qualified through the display. Further, when the electrode sheet 13 is unqualified, a reminder message can be issued through the alarm.

[0151] Optionally, before comparing the test coding array B with the standard coding array A, the method also includes: when the qualified electrode sheet 13 is connected to the adapter 20, controlling the adapter 20 to work, and determining the standard coding array A according to the analog temperature signal currently detected by each temperature detection unit 34.

[0152] Take the example of an electrode sheet 13A having 19 electrode units 33A, each electrode unit 33A corresponds to a temperature sensor 35A, that is, the corresponding detection positions numbered 1 to 19 of the electrode sheet 13A all have temperature sensors 35A, and the codes are all 1. The 19 codes are combined to obtain a 19-bit standard code array of 11111 11111 11111 1111. When the temperature sensor 35A is short-circuited, assuming that the temperature sensor 35A of the detection position numbered 1 is short-circuited, the 19-bit code array obtained is 21111111111 11111 1111. When the temperature sensor 35A is short-circuited, assuming that the temperature sensor 35A of the detection position numbered 1 is short-circuited, the 19-bit code array obtained is 01111 11111 11111 1111. By comparing the consistency of the test code array with the standard code array, it can be determined whether the electrode sheet 13A is qualified.

[0153] Take the example of an electrode sheet 13B having 13 electrode units 33B, each electrode unit 33B corresponds to a temperature sensor 35B, that is, the corresponding detection positions numbered 1 to 13 of the electrode sheet 13B all have temperature sensors 35B, and the codes are all 1. The 13 codes are combined to obtain a 13-bit standard code array 11111 11111 111. When the temperature sensor 35B is short-circuited, assuming that the temperature sensor 35B of the detection position numbered 1 is short-circuited, the 13-bit code array obtained is 21111111111111. When the temperature sensor 35B is short-circuited, assuming that the temperature sensor 35B of the detection position numbered 1 is short-circuited, the 13-bit code array obtained is 01111 11111 111. Comparing the consistency of the test code array with the standard code array can determine whether the electrode sheet 13B is qualified.

[0154] Similarly, the electrode sheets 13E, 13F, 13G having 12 electrode units 33E, 33F, 33G or the electrode sheets 13H, 13I having 9 electrode units 33H, 33I can also be applied to the above-mentioned quality inspection method, which will not be described in detail here.

[0155] Through the electrode sheet quality inspection method, during the production process of the electrode sheet 13, it is possible to monitor whether each temperature detection unit 34 of the electrode sheet 13 is connected normally, and then determine whether the electrode sheet 13 is qualified, so as to screen out unqualified electrode sheets 13, thereby ensuring that each temperature detection unit 34 of the electrode sheet 13 leaving the factory can be inspected normally.

[0156] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them; although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application, and they should all be included in the scope of the claims and specification of the present application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions that fall within the scope of the claims.

Claims

1. A tumor electric field treatment system, characterized in that: include: At least one pair of electrode sheets, each of which includes a plurality of electrode units and a plurality of temperature detection units, each of which can apply an alternating electrical signal, and each of which is provided corresponding to one electrode unit to detect the temperature at the corresponding electrode unit; wherein the plurality of electrode units are configured as a plurality of row groups and a plurality of column groups in terms of circuit connection, the electrode units in each row group are connected in parallel, so that an alternating electrical signal is simultaneously applied to the electrode units connected in parallel in each row group; the temperature detection units in each row group are connected in series; the temperature detection units in each column group are connected to a ground pin through a control switch; and the electrode units in each row group are connected in parallel and the temperature detection units in each row group are connected in series, and are connected to a bidirectional switching unit through a dual-purpose signal line; The bidirectional switching unit is configured to switch the dual-purpose signal line to connect to the temperature sampling point or the alternating power line, wherein: In the case where the dual-purpose signal line is connected to the temperature sampling point, the switch state of the control switch is configured so that the analog temperature signal detected by the temperature detection unit corresponding to one or more combinations is sampled based on the temperature sampling point; In the case where the dual-purpose signal line is connected to the alternating power line, the electrode units of at least one row group are applied with the alternating electrical signal based on the alternating power line.

2. The tumor electric field treatment system according to claim 1, characterized in that: Each of the electrode sheets further comprises a plurality of rectifying and switching modules, each of the rectifying and switching modules corresponds to one of the plurality of row groups of the electrode units, The temperature detection units in each row group are connected in series and then connected to the first end of the corresponding rectifier switching module; The electrode units in each row group are connected in parallel and then connected to the second end of the corresponding rectifying switching module; The third end of the rectifying and switching module corresponding to each row group is connected to the dual-purpose signal line corresponding to each row group.

3. The tumor electric field treatment system according to claim 2, characterized in that: The bidirectional switching unit includes a plurality of bidirectional switching switches corresponding to the plurality of row groups of the electrode units, respectively, wherein: The first end of each bidirectional switch is connected to the temperature sampling point of the corresponding row group; The second end of each of the two-way switches is simultaneously connected to the alternating power line; The third end of each bidirectional switch is connected to the dual-purpose signal line corresponding to the corresponding row group.

4. The tumor electric field treatment system according to claim 3, characterized in that: Each of the rectifier switching modules includes an electromagnetic control switch, and the electromagnetic control switch corresponding to each row group is linked with the bidirectional switch corresponding to the row group; wherein, When the bidirectional switch corresponding to each row group is switched to a state where the third end of the bidirectional switch is connected to the first end thereof, the electromagnetic control switch corresponding to the row group is switched to a state where the third end of the corresponding rectifier switching module is connected to the first end thereof, so that the analog temperature signals detected by the temperature detection units corresponding to one or more groups are sampled respectively according to the switch states of the control switches; When the bidirectional switching switch corresponding to each row group is switched to a state where its third end is conductive with its second end, the electromagnetic control switch corresponding to the row group follows and switches to a state where the third end of the corresponding rectifier switching module is conductive with its second end, so that the electrode units of each row group are simultaneously applied with the alternating electrical signal based on the alternating power line.

5. The tumor electric field treatment system according to claim 4, characterized in that: Each of the rectifier switching modules also includes a rectifier bridge and a voltage regulator tube. The first end of the rectifier bridge is connected to the dual-purpose signal line corresponding to the corresponding row group electrode unit and the third end of the electromagnetic control switch. A voltage regulator tube is connected in series between the second end of the rectifier bridge and the fourth end of the rectifier bridge. The third end of the rectifier bridge is connected to the ground pin. The anode of the voltage regulator tube is connected to the fourth end of the rectifier bridge, and the cathode of the voltage regulator tube is connected to the second end of the rectifier bridge. Each of the electromagnetic control switches includes a first end, a second end and a third end. The first end of the electromagnetic control switch constitutes the first end of the rectifier switching module, the second end of the electromagnetic control switch constitutes the second end of the rectifier switching module, and the third end of the electromagnetic control switch is connected to the first end of the rectifier bridge to constitute the third end of the rectifier switching module.

6. The tumor electric field treatment system according to claim 1, characterized in that: Each of the temperature detection units also includes a temperature sensor and a diode connected in series with the temperature sensor, the anode of each of the diodes is connected to the ground terminal of the corresponding temperature sensor, and the cathodes of the diodes corresponding to each column group are connected together and then connected to the ground pin through the corresponding control switch.

7. The tumor electric field treatment system according to claim 1, characterized in that: Each of the temperature sampling points is connected to a DC power supply via a corresponding voltage dividing resistor.

8. The tumor electric field treatment system according to claim 7, characterized in that: It also includes an adapter, wherein the control switch, the bidirectional switching unit and the voltage dividing resistor are respectively arranged in the adapter.

9. The tumor electric field treatment system according to claim 8, characterized in that: The adapter includes a first controller and an ADC unit, wherein the ADC unit is connected to each of the temperature sampling points so as to sample the analog temperature signal through each of the temperature sampling points, and the first controller is connected to the ADC unit so as to determine the temperature at the corresponding electrode unit based on the digital temperature signal output by the ADC unit.

10. The tumor electric field treatment system according to claim 9, characterized in that: The first controller is further configured to configure a switch state of the control switch.

11. The tumor electric field treatment system according to claim 9, characterized in that: The first controller is further configured to configure a switching state of the bidirectional switch in the bidirectional switching unit.

12. The tumor electric field treatment system according to claim 3, characterized in that: Also included is an electric field generator configured to output the alternating electric signal through the alternating power line.

13. The tumor electric field treatment system according to claim 12, characterized in that: The electric field generator includes a second controller and an AC signal generator. The second controller is connected to the AC signal generator. The second controller is configured to control the AC signal generator to adjust the strength of the alternating electric signal output by the alternating power line.

14. The tumor electric field treatment system according to claim 13, characterized in that: The electric field generator is further configured to obtain the temperature at each electrode unit and control the AC signal generator according to the temperature at each electrode unit.

15. The tumor electric field treatment system according to claim 13, characterized in that: The electric field generator also includes a power switch, which is arranged between the AC signal generator and the bidirectional switching unit. Under the configuration of the second controller, the power switch controls whether the AC signal generator outputs the alternating electric signal through the alternating power line.

16. The tumor electric field treatment system according to claim 13, characterized in that: The second controller is further configured to configure the switch state of the control switch.

17. The tumor electric field treatment system according to claim 13, characterized in that: The second controller is further configured to configure a switching state of the bidirectional switch in the bidirectional switching unit.

18. An electrode sheet, characterized in that: Applicable to the tumor electric field treatment system according to any one of claims 1 to 17, the tumor electric field treatment system comprises a bidirectional switching unit, and the electrode sheet comprises: substrate; A plurality of electrode units and a plurality of temperature detection units are arranged on the substrate, each of the electrode units can apply an alternating electrical signal, and each of the temperature detection units is arranged corresponding to one electrode unit to detect the temperature at the corresponding electrode unit; The plurality of electrode units are configured as a plurality of row groups and a plurality of column groups in terms of circuit connection, the electrode units in each row group are connected in parallel, so that an alternating electric signal is simultaneously applied to the electrode units connected in parallel in each row group; the temperature detection units in each row group are connected in series; the temperature detection units in each column group are connected to a ground pin through a control switch; and the electrode units in each row group are connected in parallel and the temperature detection units in each row group are connected in series to a bidirectional switching unit through a dual-purpose signal line; In the case where the dual-purpose signal line is connected to the temperature sampling point, the switch state of the control switch is configured so that the analog temperature signal detected by the temperature detection unit corresponding to one or more combinations is sampled based on the temperature sampling point; In the case where the dual-purpose signal line is connected to the alternating power line, the electrode units of at least one row group are applied with the alternating electrical signal based on the alternating power line.

19. A method for detecting electrode temperature, characterized in that: Applied to the tumor electric field treatment system according to any one of claims 1 to 17, the method comprising: Controlling the bidirectional switching unit so that the dual-purpose signal line corresponding to any row group of the corresponding electrode sheets is connected to the corresponding temperature sampling point; The control switch corresponding to each column group is controlled so as to sample the analog temperature signal of the corresponding electrode unit based on the corresponding temperature sampling point.

20. The method according to claim 19, characterized in that When the dual-purpose signal lines corresponding to each row group are respectively connected to the corresponding temperature sampling points, the control switches corresponding to each column group are controlled, including: The control switches corresponding to the column groups are controlled to be closed in sequence, so as to respectively sample the analog temperature signals of the electrode units in each row group.

21. A method for detecting the quality of an electrode sheet, characterized in that: A quality detection system for an electrode sheet, the quality detection system for the electrode sheet comprising the tumor electric field therapy system according to any one of claims 1 to 17 and a host computer, the host computer and the tumor electric field therapy system are communicatively connected, and the method comprises: Acquire an analog temperature signal detected by each of the temperature detection units in the electrode sheet; Determine the state of each temperature detection unit according to the analog temperature signal detected by each temperature detection unit, and assign a corresponding code to determine the test code array of the electrode sheet; The test coding array is compared with the standard coding array for consistency to determine whether the electrode sheet is qualified, wherein the standard coding includes at least the first coding and the second coding, the first coding is used to indicate that the temperature detection unit is in a normal state, and the second coding is used to indicate that the temperature detection unit is in an open circuit state or an unset state.

22. The method for detecting the quality of an electrode sheet according to claim 21, characterized in that: The test code array includes at least one of a first code, a second code and a third code, and the third code is used to indicate that the temperature detection unit is in a short-circuit state.

23. The method for detecting the quality of an electrode sheet according to claim 21, characterized in that: The analog temperature signal is characterized by a voltage value, and the test code array of the electrode sheet is determined according to the analog temperature signal detected by each temperature detection unit, including: Determining a voltage interval in which the voltage value is located; Determine the code corresponding to the corresponding temperature detection unit according to the voltage interval in which the voltage value is located, wherein different voltage intervals in which the voltage value is located correspond to different codes; A test code array of the corresponding electrode sheet is generated according to the code corresponding to each temperature detection unit.

24. The method for detecting the quality of an electrode sheet according to claim 23, characterized in that: Before comparing the test encoding array with the standard encoding array, the method further includes: When the electrode sheet that has passed the test is connected to the adapter of the tumor electric field treatment system, the adapter is controlled to work, and the standard coding array is determined according to the analog temperature signal currently detected by each of the temperature detection units.

25. A quality inspection system for an electrode sheet, characterized in that: It comprises the tumor electric field therapy system as described in any one of claims 1-17, a host computer, an alarm and a display, the host computer and the tumor electric field therapy system are communicatively connected, the alarm and the host computer are communicatively connected, the display and the host computer are communicatively connected, and the electrode sheet quality detection system is used to execute the electrode sheet quality detection method according to any one of claims 21-24.

Images