Compound component for treating Alzheimer's disease and resisting aging and preparation method thereof

Abstract

The invention provides a compound component for treating Alzheimer's disease and resisting aging and a preparation method thereof, and relates to the technical field of medicine preparation. The compound component mainly consists of six raw material medicines, namely a ginger extract, a herba cistanche extract, a radix salviae miltiorrhizae extract, a lucid ganoderma extract, a rhizoma polygonati extract and a liquorice root extract. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 10 to 20 parts of ginger extract, 20 to 40 parts of herba cistanche extract, 10 to 15 parts of radix salviae miltiorrhizae extract, 15 to 30 parts of lucid ganoderma extract, 5 to 10 parts of rhizoma polygonati extract, 3 to 5 parts of liquorice root extract and 5 to 10 parts of surfactant. According to the invention, the compound component can play a therapeutic role through a plurality of mechanisms, including oxidation resistance, inflammation resistance, neuroprotection, immunoregulation and the like, adopts natural medicinal components, is high in safety and small in side effect, can obviously improve cognitive function and improve memory, has an anti-aging effect, and can be used for preparing the traditional Chinese medicine composition. The aging process of an organism can be delayed.

Description

Technical Field

[0001] The invention relates to the technical field of medicine preparation, in particular to a compound component for treating Alzheimer's disease and resisting aging and a preparation method thereof. Background Art

[0002] Alzheimer's disease (AD) is a common neurodegenerative disease, which is mainly manifested by symptoms such as cognitive decline, memory loss, language disorders and abnormal behavior. With the intensification of global aging, the incidence of Alzheimer's disease has increased year by year and has become one of the main factors affecting the quality of life of the elderly.

[0003] At present, the etiology and pathogenesis of Alzheimer's disease have not been fully elucidated, and are mainly related to multiple factors such as β-amyloid protein (Aβ) deposition, neurofibrillary tangles, oxidative stress and neuroinflammation. Aging is a complex physiological process, which is closely related to the occurrence of various chronic diseases. With the increase of age, the body's immune function, metabolic function and antioxidant capacity gradually decline, which is prone to cause various diseases. Therefore, the development of drugs with anti-aging effects is of great significance to improving the quality of life of the elderly.

[0004] Existing Alzheimer's disease treatment drugs mainly include acetylcholinesterase inhibitors and NMDA receptor antagonists, but these drugs can only temporarily relieve symptoms and cannot prevent the progression of the disease, and long-term use may have significant side effects. Therefore, it is urgent to develop new therapeutic drugs with better efficacy and fewer side effects.

[0005] Traditional Chinese medicine has unique advantages in preventing and treating neurodegenerative diseases. Through compound prescriptions, it can achieve multi-target and multi-pathway synergistic effects to improve patients' symptoms and quality of life. Chinese medicinal materials such as ginger, Cistanche deserticola, and Ganoderma lucidum have significant antioxidant, anti-inflammatory, neuroprotective and immunomodulatory effects, and play an important role in the prevention and treatment of anti-aging and neurodegenerative diseases.

[0006] Therefore, those skilled in the art provide a compound component for treating Alzheimer's disease and anti-aging and a preparation method thereof to solve the problems raised in the above background technology. Summary of the invention

[0007] 1. Technical issues to be resolved In view of the deficiencies in the prior art, the present invention provides a compound component for treating Alzheimer's disease and anti-aging and a preparation method thereof, which can effectively treat Alzheimer's disease and has anti-aging effects. Through scientific proportioning and preparation methods, the synergistic effect of each component is fully exerted, and a safe and effective treatment plan is provided, which solves the problem that existing Alzheimer's disease treatment drugs mainly include acetylcholinesterase inhibitors and NMDA receptor antagonists, but these drugs can only temporarily relieve symptoms, cannot prevent the progression of the disease, and long-term use may produce obvious side effects.

[0008] (II) Technical solution To achieve the above objectives, the present invention is implemented through the following technical solutions: A compound component for treating Alzheimer's disease and anti-aging, mainly composed of six raw materials: ginger extract, Cistanche extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract, and the weight proportions of each component are respectively: 10-20 parts of ginger extract, 20-40 parts of Cistanche extract, 10-15 parts of Salvia miltiorrhiza extract, 15-30 parts of Ganoderma lucidum extract, 5-10 parts of Polygonatum sibiricum extract, 3-5 parts of Licorice extract, and 5-10 parts of surfactant.

[0009] Furthermore, the weight proportions of the components are: 15 parts of ginger extract, 25 parts of Cistanche deserticola extract, 12 parts of Salvia miltiorrhiza extract, 22 parts of Ganoderma lucidum extract, 8 parts of Polygonatum sibiricum extract, 4 parts of Licorice extract, and 7 parts of surfactant.

[0010] Furthermore, the weight proportions of the components are: 20 parts of ginger extract, 40 parts of Cistanche deserticola extract, 15 parts of Salvia miltiorrhiza extract, 30 parts of Ganoderma lucidum extract, 10 parts of Polygonatum sibiricum extract, 5 parts of Licorice extract, and 10 parts of surfactant.

[0011] Furthermore, the weight proportions of the components are: 10 parts of ginger extract, 20 parts of Cistanche deserticola extract, 10 parts of Salvia miltiorrhiza extract, 15 parts of Ganoderma lucidum extract, 5 parts of Polygonatum sibiricum extract, 3 parts of Licorice extract, and 5 parts of surfactant.

[0012] Furthermore, the surfactant is selected from one or more combinations of polyoxyethylene ether-40 hydrogenated castor oil, poloxamer 188, and lecithin E-80.

[0013] Furthermore, the dosage forms of the compound components include tablets, capsules and granules.

[0014] Furthermore, a method for preparing a compound component for treating Alzheimer's disease and anti-aging comprises the following steps: Step 1. Extraction Ginger, Cistanche deserticola, Ganoderma lucidum, Salvia miltiorrhiza, Polygonatum sibiricum and Licorice were crushed separately, then extracted with 70% ethanol under reflux, the extracts were combined and then concentrated under reduced pressure; Step 2. Purification Purification was performed by HPD100 macroporous resin, and the 70% ethanol eluate was collected, concentrated and dried to obtain the respective extracts; Step 3. Mix The ginger extract, the Cistanche deserticola extract, the Ganoderma lucidum extract, the Salvia miltiorrhiza extract, the Polygonatum sibiricum extract, and the Licorice extract are uniformly mixed according to the weight ratio, and a surfactant is added to the mixture, and the mixture is fully stirred and mixed to obtain a mixed paste; Step 4. Preparation The mixed paste is prepared into tablets, capsules or granules as required.

[0015] Furthermore, the preparation process of the compound component as a finished capsule is as follows: 1) Stir and mix ginger extract, Cistanche deserticola extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract, and then stir and mix the mixed powder, surfactant, and appropriate amounts of auxiliary materials, such as microcrystalline cellulose and silicon dioxide; 2) Dry the mixture to control the moisture content below 5%; 3) Use a capsule filling machine to fill the mixture into hollow capsules with accurate filling amount to obtain the finished product; The preparation process of the compound component as a granule finished product is as follows: 1) Ginger extract, Cistanche deserticola extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract are mixed by high-speed stirring at a stirring speed of 2900 rpm, and a surfactant is added during the stirring and mixing process, and the mixture is homogenized again; 2) Place the mixture in an ultrasonic device and perform ultrasonic treatment for 20 to 30 minutes at a frequency of 50 to 60 Hz; 3) Then send it to the granulator for granulation to obtain the semi-finished Chinese medicine granules; 4) The semi-finished product is then dried to obtain the finished granule product.

[0016] Furthermore, the compound component is used in the preparation of drugs for treating Alzheimer's disease and anti-aging.

[0017] (III) Beneficial effects The present invention provides a compound component for treating Alzheimer's disease and resisting aging and a preparation method thereof. It has the following beneficial effects: 1. The present invention provides a compound component for treating Alzheimer's disease and anti-aging and a preparation method thereof. The compound component can exert therapeutic effects through multiple mechanisms, including anti-oxidation, anti-inflammatory, neuroprotection, immunomodulation, etc. The compound can significantly improve cognitive function, enhance memory, and has a good therapeutic effect on Alzheimer's disease. At the same time, the compound component has anti-aging effects and can delay the aging process of the body.

[0018] 2. The present invention provides a compound component for treating Alzheimer's disease and anti-aging and a preparation method thereof, which uses natural drug ingredients, has high safety, and few side effects, and improves the therapeutic effect through the synergistic effect of multiple targets and multiple pathways.

[0019] 3. The present invention provides a compound component for treating Alzheimer's disease and anti-aging and a preparation method thereof. The preparation method is simple and can be industrialized for production. It can be used to prepare drugs for treating Alzheimer's disease and anti-aging and has broad application prospects. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the inhibitory activity of the compound extract of the present invention on AChE. DETAILED DESCRIPTION

[0021] In order to further understand the present invention, the technical scheme in the specific implementation of the present invention will be clearly and completely described below in conjunction with the drawings in the specific implementation of the present invention. Obviously, the specific implementation described is only a part of the specific implementation of the present invention, rather than all the specific implementations. Based on the specific implementation of the present invention, all other specific implementations obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0022] Unless otherwise specified, the reagents involved in the specific embodiments of the present invention are all commercially available products and can be purchased through commercial channels.

[0023] Selection of raw materials 1. Ginger: Rich in gingerol, gingerone, etc., it has antioxidant, anti-inflammatory and anti-aging effects.

[0024] 2. Cistanche deserticola: Contains phenylethanol glycosides, lignans, etc., which have the effects of improving memory, anti-fatigue, and anti-oxidation.

[0025] 3. Ganoderma lucidum: Rich in triterpenes, polysaccharides, etc., it has immunomodulatory, antioxidant and neuroprotective effects.

[0026] 4. Salvia miltiorrhiza: Contains tanshinone, salvianolic acid and flavonoids, which have antioxidant, anti-inflammatory, anticoagulant and cardiovascular and nervous system protective effects.

[0027] 5. Polygonatum sibiricum: Contains saponins, amino acids, betaine, zinc and other trace elements. It has immune-enhancing and immunomodulatory effects, can dilate blood vessels, inhibit platelet aggregation, reduce blood viscosity, and improve blood circulation and brain perfusion.

[0028] 6. Licorice: Contains a variety of chemical components, the main components are glycyrrhizic acid and glycyrrhizin, which have the effects of regulating body immunity, anti-aging, anti-inflammatory, anti-pathogenic microorganisms, sedation, anti-tumor, improving cardiovascular, tonifying spleen and qi, moistening lungs and relieving cough, clearing away heat and detoxifying, relieving pain, alleviating medicinal properties, and removing expectorant. Specific implementation 1: A specific embodiment of the present invention provides a compound component for treating Alzheimer's disease and anti-aging, which is mainly composed of six raw materials: ginger extract, Cistanche extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract. The weight proportions of each component are: 15 parts of ginger extract, 25 parts of Cistanche extract, 12 parts of Salvia miltiorrhiza extract, 22 parts of Ganoderma lucidum extract, 8 parts of Polygonatum sibiricum extract, 4 parts of Licorice extract, and 7 parts of surfactant.

[0030] By adopting the method of 70% ethanol reflux extraction and macroporous resin purification, an extract rich in active ingredients is obtained, and after mixing, it can be prepared into oral preparations such as tablets, capsules, granules, etc.

[0031] The surfactant is selected from polyoxyethylene ether-40 hydrogenated castor oil.

[0032] The preparation method of the compound component for treating Alzheimer's disease and resisting aging comprises the following steps: Step 1. Extraction Ginger, Cistanche deserticola, Ganoderma lucidum, Salvia miltiorrhiza, Polygonatum sibiricum and Licorice were crushed separately, then extracted with 70% ethanol under reflux, the extracts were combined and then concentrated under reduced pressure; Step 2. Purification Purification was performed by HPD100 macroporous resin, and the 70% ethanol eluate was collected, concentrated and dried to obtain the respective extracts; Step 3. Mix The ginger extract, the Cistanche deserticola extract, the Ganoderma lucidum extract, the Salvia miltiorrhiza extract, the Polygonatum sibiricum extract, and the Licorice extract are uniformly mixed according to the weight ratio, and a surfactant is added to the mixture, and the mixture is fully stirred and mixed to obtain a mixed paste; Step 4. Preparation The mixed paste is prepared into tablets, capsules or granules as required.

[0033] The preparation process of the compound component as a finished capsule is as follows: 1) Stir and mix ginger extract, Cistanche deserticola extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract, and then stir and mix the mixed powder, surfactant, and appropriate amounts of auxiliary materials, such as microcrystalline cellulose and silicon dioxide; 2) Dry the mixture to control the moisture content below 5%; 3) Use a capsule filling machine to fill the mixture into hollow capsules with accurate filling amount to obtain the finished product; The preparation process of the compound component as a granule finished product is as follows: 1) Ginger extract, Cistanche deserticola extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract are mixed by high-speed stirring at a stirring speed of 2900 rpm, and a surfactant is added during the stirring and mixing process, and the mixture is homogenized again; 2) The mixture was ultrasonicated in an ultrasonicator for 25 min at a frequency of 55 Hz; 3) Then send it to the granulator for granulation to obtain the semi-finished Chinese medicine granules; 4) The semi-finished product is then dried to obtain the finished granule product.

[0034] The preparation method of the compound component as a finished tablet is the same as that of the capsule, except that a tablet machine is used for the final tableting process. Specific implementation 2: A specific embodiment of the present invention provides a compound component for treating Alzheimer's disease and anti-aging, which is mainly composed of six raw materials: ginger extract, Cistanche extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract. The weight parts of each component are respectively: 20 parts of ginger extract, 40 parts of Cistanche extract, 15 parts of Salvia miltiorrhiza extract, 30 parts of Ganoderma lucidum extract, 10 parts of Polygonatum sibiricum extract, 5 parts of Licorice extract, and 10 parts of surfactant.

[0036] By adopting the method of 70% ethanol reflux extraction and macroporous resin purification, an extract rich in active ingredients is obtained, and after mixing, it can be prepared into oral preparations such as tablets, capsules, granules, etc.

[0037] The surfactant is selected from Poloxamer 188.

[0038] The preparation method of the compound component for treating Alzheimer's disease and resisting aging comprises the following steps: Step 1. Extraction Ginger, Cistanche deserticola, Ganoderma lucidum, Salvia miltiorrhiza, Polygonatum sibiricum and Licorice were crushed separately, then extracted with 70% ethanol by reflux, the extracts were combined, and then concentrated under reduced pressure; Step 2. Purification Purification was performed by HPD100 macroporous resin, and the 70% ethanol eluate was collected, concentrated and dried to obtain the respective extracts; Step 3. Mix The ginger extract, the Cistanche deserticola extract, the Ganoderma lucidum extract, the Salvia miltiorrhiza extract, the Polygonatum sibiricum extract, and the Licorice extract are uniformly mixed according to the weight ratio, and a surfactant is added to the mixture, and the mixture is fully stirred and mixed to obtain a mixed paste; Step 4. Preparation The mixed paste is prepared into tablets, capsules or granules as required.

[0039] The preparation process of the compound component as a finished capsule is as follows: 1) Stir and mix ginger extract, Cistanche deserticola extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract, and then stir and mix the mixed powder, surfactant, and appropriate amounts of auxiliary materials, such as microcrystalline cellulose and silicon dioxide; 2) Dry the mixture to control the moisture content below 5%; 3) Use a capsule filling machine to fill the mixture into hollow capsules with accurate filling amount to obtain the finished product; The preparation process of the compound component as a granule finished product is as follows: 1) Ginger extract, Cistanche deserticola extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract are mixed by high-speed stirring at a stirring speed of 2900 rpm, and a surfactant is added during the stirring and mixing process, and the mixture is homogenized again; 2) The mixture was ultrasonicated in an ultrasonicator for 30 min at a frequency of 60 Hz; 3) Then send it to the granulator for granulation to obtain the semi-finished Chinese medicine granules; 4) The semi-finished product is then dried to obtain the finished granule product.

[0040] The preparation method of the compound component as a finished tablet is the same as that of the capsule, except that a tablet machine is used for the final tableting process. Specific implementation 3: A specific embodiment of the present invention provides a compound component for treating Alzheimer's disease and anti-aging, which is mainly composed of six raw materials: ginger extract, Cistanche extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract. The weight parts of each component are respectively: 10 parts of ginger extract, 20 parts of Cistanche extract, 10 parts of Salvia miltiorrhiza extract, 15 parts of Ganoderma lucidum extract, 5 parts of Polygonatum sibiricum extract, 3 parts of Licorice extract, and 5 parts of surfactant.

[0042] By adopting the method of 70% ethanol reflux extraction and macroporous resin purification, an extract rich in active ingredients is obtained, and after mixing, it can be prepared into oral preparations such as tablets, capsules, granules, etc.

[0043] The surfactant is selected from lecithin E-80.

[0044] The preparation method of the compound component for treating Alzheimer's disease and resisting aging comprises the following steps: Step 1. Extraction Ginger, Cistanche deserticola, Ganoderma lucidum, Salvia miltiorrhiza, Polygonatum sibiricum and Licorice were crushed separately, then extracted with 70% ethanol under reflux, the extracts were combined and then concentrated under reduced pressure; Step 2. Purification Purification was performed by HPD100 macroporous resin, and the 70% ethanol eluate was collected, concentrated and dried to obtain the respective extracts; Step 3. Mix The ginger extract, the Cistanche deserticola extract, the Ganoderma lucidum extract, the Salvia miltiorrhiza extract, the Polygonatum sibiricum extract, and the Licorice extract are uniformly mixed according to the weight ratio, and a surfactant is added to the mixture, and the mixture is fully stirred and mixed to obtain a mixed paste; Step 4. Preparation The mixed paste is prepared into tablets, capsules or granules as required.

[0045] The preparation process of the compound component as a finished capsule is as follows: 1) Stir and mix ginger extract, Cistanche deserticola extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract, and then stir and mix the mixed powder, surfactant, and appropriate amounts of auxiliary materials, such as microcrystalline cellulose and silicon dioxide; 2) Dry the mixture to control the moisture content below 5%; 3) Use a capsule filling machine to fill the mixture into hollow capsules with accurate filling amount to obtain the finished product; The preparation process of the compound component as a granule finished product is as follows: 1) Ginger extract, Cistanche deserticola extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract are mixed by high-speed stirring at a stirring speed of 2900 rpm, and a surfactant is added during the stirring and mixing process, and the mixture is homogenized again; 2) The mixture was placed in an ultrasonicator and sonicated for 20 min at a frequency of 50 Hz; 3) Then send it to the granulator for granulation to obtain the semi-finished Chinese medicine granules; 4) The semi-finished product is then dried to obtain the finished granule product.

[0046] The preparation method of the compound component as a finished tablet is the same as that of the capsule, except that a tablet machine is used for the final tableting process.

[0047] Pharmacological experiments: The present invention uses in vitro bioactivity assays to evaluate the inhibitory effects of the compound components on Alzheimer's disease-related targets, mainly by measuring the half-maximal inhibitory concentration (IC 50 ) for evaluation.

[0048] Acetylcholinesterase (AChE) inhibitory activity assay Reagent preparation: prepare compound extract solutions of different concentrations (concentration range: 0.01 mg / mL to 1 mg / mL); Enzyme reaction: The compound solution was mixed with AChE enzyme and substrate acetylthiocholine (ATCI) at 37°C for 15 min; Detection: Add 5,5'-dithiobis(2-nitrobenzoic acid) (DTNB) and measure the absorbance at 412 nm.

[0049] Result analysis: Calculate the AChE inhibition rate at each concentration and plot the inhibition rate against the logarithm of the concentration, as shown in Figure 1 As shown, calculate IC 50 value.

[0050] Experimental results: IC of the compound components to AChE 50 The value was 20.32 mM, showing strong inhibitory activity.

[0051] Application prospects: The compound components of the present invention have been verified by in vitro experiments to have significant inhibitory effects on Alzheimer's disease-related targets, and may have multiple functions such as anti-oxidation, neuroprotection and inhibition of Aβ aggregation.

[0052] Because it uses natural medicinal ingredients and is highly safe, it can be used to prepare drugs for the treatment of Alzheimer's disease and anti-aging, and has broad market prospects.

[0053] Although specific embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the specific embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A compound component for treating Alzheimer's disease and anti-aging, mainly composed of six raw materials: ginger extract, Cistanche deserticola extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract, characterized in that: The weight proportions of the components are: 10-20 parts of ginger extract, 20-40 parts of Cistanche deserticola extract, 10-15 parts of Salvia miltiorrhiza extract, 15-30 parts of Ganoderma lucidum extract, 5-10 parts of Polygonatum sibiricum extract, 3-5 parts of Licorice extract and 5-10 parts of surfactant.

2. The compound composition for treating Alzheimer's disease and resisting aging according to claim 1, characterized in that: The weight proportions of the components are as follows: 15 parts of ginger extract, 25 parts of Cistanche deserticola extract, 12 parts of Salvia miltiorrhiza extract, 22 parts of Ganoderma lucidum extract, 8 parts of Polygonatum sibiricum extract, 4 parts of Licorice extract and 7 parts of surfactant.

3. The compound composition for treating Alzheimer's disease and resisting aging according to claim 1, characterized in that: The weight proportions of the components are as follows: 20 parts of ginger extract, 40 parts of Cistanche deserticola extract, 15 parts of Salvia miltiorrhiza extract, 30 parts of Ganoderma lucidum extract, 10 parts of Polygonatum sibiricum extract, 5 parts of Licorice extract and 10 parts of surfactant.

4. The compound composition for treating Alzheimer's disease and resisting aging according to claim 1, characterized in that: The weight proportions of the components are as follows: 10 parts of ginger extract, 20 parts of Cistanche deserticola extract, 10 parts of Salvia miltiorrhiza extract, 15 parts of Ganoderma lucidum extract, 5 parts of Polygonatum sibiricum extract, 3 parts of Licorice extract and 5 parts of surfactant.

5. The compound composition for treating Alzheimer's disease and resisting aging according to claim 1, characterized in that: The surfactant is selected from one or more combinations of polyoxyethylene ether-40 hydrogenated castor oil, poloxamer 188, and lecithin E-80.

6. The compound composition for treating Alzheimer's disease and resisting aging according to claim 1, characterized in that: The dosage forms of the compound components include tablets, capsules and granules.

7. A method for preparing the compound component for treating Alzheimer's disease and anti-aging as claimed in claim 1, characterized in that: The following steps are involved: Step 1. Extraction Ginger, Cistanche deserticola, Ganoderma lucidum, Salvia miltiorrhiza, Polygonatum sibiricum and Licorice were crushed separately, then extracted with 70% ethanol by reflux, the extracts were combined, and then concentrated under reduced pressure; Step 2. Purification Purification was performed by HPD100 macroporous resin, and the 70% ethanol eluate was collected, concentrated and dried to obtain the respective extracts; Step 3. Mix The ginger extract, the Cistanche deserticola extract, the Ganoderma lucidum extract, the Salvia miltiorrhiza extract, the Polygonatum sibiricum extract, and the Licorice extract are uniformly mixed according to the weight ratio, and a surfactant is added to the mixture, and the mixture is fully stirred and mixed to obtain a mixed paste; Step 4. Preparation The mixed paste is prepared into tablets, capsules or granules as required.

8. The method for preparing the compound component for treating Alzheimer's disease and resisting aging according to claim 7, characterized in that: The preparation process of the compound component as a finished capsule is as follows: 1) Stir and mix ginger extract, Cistanche deserticola extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract, and then stir and mix the mixed powder, surfactant, and appropriate amounts of auxiliary materials, such as microcrystalline cellulose and silicon dioxide; 2) Dry the mixture to control the moisture content below 5%; 3) Use a capsule filling machine to fill the mixture into hollow capsules with accurate filling amount to obtain the finished product; The preparation process of the compound component as a granule finished product is as follows: 1) Ginger extract, Cistanche deserticola extract, Salvia miltiorrhiza extract, Ganoderma lucidum extract, Polygonatum sibiricum extract, and Licorice extract are mixed by high-speed stirring at a stirring speed of 2900 rpm, and a surfactant is added during the stirring and mixing process, and the mixture is homogenized again; 2) Place the mixture in an ultrasonic device and perform ultrasonic treatment for 20 to 30 minutes at a frequency of 50 to 60 Hz; 3) Then send it to the granulator for granulation to obtain the semi-finished Chinese medicine granules; 4) The semi-finished product is then dried to obtain the finished granule product.

9. Use of the compound component according to claim 1 in the preparation of drugs for treating Alzheimer's disease and anti-aging.

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