Tumor cell medical examination sampling device and sampling method thereof

Abstract

The invention relates to the technical field of needle biopsy, in particular to a tumor cell medical examination sampling device and a sampling method thereof.The tumor cell medical examination sampling device comprises a puncture assembly and a guide assembly matched with the puncture assembly; the guide assembly comprises a mounting cylinder, a sampling assembly is arranged in the mounting cylinder, and a steering assembly is arranged at the bottom of the mounting cylinder; the steering assembly comprises an adjusting ball arranged at the bottom of the mounting cylinder, a through groove is formed in the adjusting ball in a penetrating mode, a transmission part is arranged on the outer side of the adjusting ball, and the transmission part and the through groove are in a mutually perpendicular state; the sampling assembly comprises a piston disc, an extraction assembly is arranged at one end, away from the steering assembly, of the piston disc, and a suction needle is arranged at one end, facing the steering assembly, of the piston disc; after the adjusting ball is driven by the transmission part to deflect, the end, away from the piston disc, of the suction needle synchronously deflects when extending out of the mounting cylinder through the through groove, so that the suction needle can avoid important parts of a human body during biopsy sampling, and the phenomenon of mistaken penetration during sampling is avoided.

Description

Technical Field

[0001] The invention relates to the technical field of puncture biopsy, and in particular to a tumor cell medical inspection sampling device and a sampling method thereof. Background Art

[0002] As a medical device widely used in the field of tumor treatment, negative pressure puncture needles are mainly used in biopsy (biopsy) and tumor ablation technology. In the application scenario of biopsy, the operation process of negative pressure puncture needles usually includes the following steps: first, under the guidance of medical imaging technologies such as CT, X-ray or ultrasound, accurately determine the location and size of the lesion, and make clear marks on the corresponding surface skin; then, disinfect and anesthetize the marked area; then, use the biopsy puncture needle to accurately puncture from the marked point to the lesion site; finally, use negative pressure technology to achieve sampling of the target tissue for inspection and analysis.

[0003] However, the existing negative pressure puncture needles face a significant problem in actual use, that is, the conventional puncture needles have insufficient negative pressure stability. This problem easily leads to unsatisfactory aspiration of tissues or cells at the puncture site, and thus it is difficult to meet the strict requirements of clinical pathology smear examination on sample quality and quantity.

[0004] The Chinese patent application number is CN201610184632.7, which discloses a pressure-readable negative pressure puncture device, including a syringe barrel and a negative pressure gauge. A piston rod is arranged inside the syringe barrel, a piston is arranged at the front end of the piston rod, a negative pressure control valve is arranged on the syringe mouth of the syringe barrel, a piston rod telescopic locking device is arranged between the syringe barrel and the piston rod, the piston rod telescopic locking device adjusts the negative pressure between the piston and the negative pressure control valve, and the connector of the negative pressure gauge is connected with the syringe barrel at the front end of the piston through a pipeline. The negative pressure control valve is closed before puncture, the piston rod is pulled back to form a negative pressure in the syringe barrel, the piston rod telescopic locking device is used to adjust the negative pressure in the syringe barrel, and the negative pressure value in the syringe barrel is accurately read by the negative pressure gauge. This device effectively avoids the influence of pulling the syringe piston on the negative pressure, the influence of the syringe shaking and the distraction of attention on the positioning, and the whole negative pressure puncture device is light, beautiful and easy to operate.

[0005] Although the above-mentioned device has successfully used the radial contraction control mechanism to achieve the precise locking of the negative pressure in the syringe and ensure the stability of the negative pressure, it still faces a series of challenges in clinical practice. In particular, when performing puncture operations, the puncture needle often needs to pass through the complex structure of the human body, including important blood vessels, organs, and tumor areas adjacent to bones. These areas are not only highly sensitive, but also have key physiological functions. Once they are mistakenly punctured, they may cause serious consequences such as pneumothorax, blood vessel rupture, and organ failure, posing a major risk of medical accidents.

[0006] Therefore, when encountering important tissues or organs that must be avoided during the puncture path, doctors usually need to explore alternative paths. However, due to the complexity of the human anatomy, it is often difficult to find other suitable puncture paths, which directly affects the effective implementation of puncture biopsy and hinders the achievement of treatment goals.

[0007] In addition, during the sampling process, the puncture needle is also at risk of clogging, and such clogging is often difficult to detect immediately. Clogging not only significantly increases the difficulty of tissue aspiration, but also, when doctors try to remove the blockage by increasing the negative pressure, it is very easy to damage the surrounding tissue due to excessive operation, which undoubtedly further increases the complexity and potential risks of treatment.

[0008] In view of this, it is particularly important and urgent to develop a tumor cell medical inspection sampling device and a sampling method thereof that can overcome the above-mentioned technical difficulties. Summary of the invention

[0009] The object of the present invention is to provide a tumor cell medical test sampling device and a sampling method thereof to solve the technical problems raised in the above background technology.

[0010] To achieve the above object, the present invention provides the following technical solutions: A tumor cell medical test sampling device, comprising a puncture component and a guide component adapted thereto; The guide assembly comprises a mounting tube, a sampling assembly movably arranged along its axial direction is arranged inside the mounting tube, and a steering assembly for adjusting the direction of the sampling assembly is arranged at the bottom of the mounting tube; The steering assembly comprises an adjusting ball arranged at the bottom of the mounting cylinder, a through slot is arranged through the adjusting ball, a transmission member for driving the adjusting ball to deflect is arranged on the outer side of the adjusting ball, and the transmission member and the through slot are in a mutually perpendicular state; The sampling assembly includes a piston disk movably connected to the inner wall of the mounting tube, an extraction assembly is provided at one end of the piston disk away from the steering assembly, and a suction needle is provided at one end of the piston disk facing the steering assembly. After the adjustment ball is deflected, when the suction needle extends out of the mounting tube through the through slot, the end of the suction needle away from the piston disk is deflected synchronously.

[0011] Preferably, a mounting block is provided at the end of the mounting cylinder away from the adjusting ball, and a pneumatic channel connected to the mounting cylinder is opened on the mounting block. A pneumatic interface connected to the pneumatic channel is provided on the outer side of the mounting block. By adjusting the gas flow direction in the pneumatic channel, the gap between the piston disk and the mounting block is controlled, and the piston disk is reciprocated along the axial direction of the mounting cylinder.

[0012] Preferably, the transmission member comprises a connecting shaft symmetrically arranged on the adjusting ball, the connecting shaft is rotatably connected to the mounting cylinder, and the straight line formed by the two connecting shafts and the through slot are in a mutually perpendicular state; A traction rope is wound around the two connecting shafts, and the other ends of the two traction ropes are commonly connected to a rotating shaft, the rotating shaft is arranged inside the mounting block, and a rotating block is arranged at one end of the rotating shaft passing through the mounting block; The installation cylinder is provided with a traction channel for the traction rope to move.

[0013] Preferably, the two traction ropes distributed on the rotating shaft have their own characteristics in their winding modes; The first traction rope is wound around the rotating shaft in a clockwise direction, while the winding direction of the first traction rope around the connecting shaft is counterclockwise; The second traction rope is wound around the rotating shaft in a counterclockwise direction, while the winding direction between the second traction rope and the connecting shaft is clockwise.

[0014] Preferably, the extraction assembly comprises a connecting hose arranged on the piston disc, the connecting hose is connected to the suction needle, and one end of the connecting hose away from the piston disc is connected to the mounting block; An escape channel communicating with the connecting hose is provided inside the mounting block, and an extraction interface is provided at the end of the escape channel.

[0015] Preferably, the suction needle comprises a needle tube portion connected to the piston disc, the needle tube portion is communicated with the connecting hose, and the needle tube portion is adapted to the through groove; A needle head is arranged at one end of the needle tube part away from the piston disc, and an array of oblique holes are arranged on the outer side of the needle head part, and the oblique holes are communicated with the needle tube part.

[0016] Preferably, the puncture assembly comprises an outer puncture sleeve with an oblique structure, a puncture inner core with a pointed tip passes through the inner part of the outer puncture sleeve, and a connecting portion for docking with the puncture inner core is provided at the top of the outer puncture sleeve.

[0017] Preferably, the connecting portion comprises a fixing cap arranged at the end of the puncture outer sleeve, an end of the fixing cap away from the puncture outer sleeve is provided with a mounting groove, a fixing plate is arranged on the outer side of the fixing cap, and an angle indicating groove is arranged on the fixing plate; An angle plate is provided between the mounting tube and the mounting block, and the angle plate is matched with the mounting groove.

[0018] Preferably, a fitting portion is provided at one end of the mounting tube away from the mounting block, the fitting portion covers the outer wall of the adjusting ball, and the length of the fitting portion is greater than the radius of the through slot.

[0019] A sampling method for a tumor cell medical testing sampling device, the sampling method comprising the following steps: S1. Use CT technology to perform a whole-body or local scan of the patient to identify the location of the lesion. By analyzing the CT scan data, use image processing software to assist in determining the optimal needle insertion point, and make a mark on the corresponding position on the patient's body surface to provide guidance for subsequent operations; S2. After the puncture point is determined, the puncture area is disinfected and local anesthesia is performed to ensure the sterility of the operating environment and relieve the patient's pain; S3. According to the pre-planned puncture path and orientation, guide the puncture assembly to the edge of the lesion. After reaching the predetermined depth, remove the puncture core inside the puncture outer sleeve to create the necessary space for subsequent sampling operations; S4. Insert the guide assembly into the puncture outer sleeve, adjust the angle of the adjustment ball through the transmission member, ensure that the through slot on the guide assembly is aligned with the lesion position, stimulate the suction needle, and guide the suction needle through the through slot to perform biopsy sampling on the lesion; S5. After the biopsy sampling is completed, first remove the guide assembly, then return the puncture core to its original position, and finally smoothly remove the puncture assembly from the patient's body; S6. Properly cover the puncture area with a sterile dressing to reduce the risk of infection and promote wound healing.

[0020] Technical effects and advantages of the present invention: 1. The present invention realizes precise control of the suction needle during the biopsy sampling process through the mutual cooperation of the puncture component and the guide component. Specifically, the steering component in the guide component can drive the adjustment ball to deflect, thereby driving the suction needle to deflect synchronously when extending out of the mounting tube, thereby effectively avoiding key parts of the human body and preventing the occurrence of accidental puncture accidents. 2. The present invention realizes the control of the gap between the piston disc and the mounting block through the cooperation of the pneumatic device on the mounting block and the pneumatic interface, thereby realizing the reciprocating movement of the suction needle driven by the piston disc along the axial direction of the mounting cylinder, thereby enhancing the flexibility and accuracy of sampling.

[0021] 3. The present invention enables the adjusting ball to be deflected to a specified angle according to actual needs through the cooperation between the transmission member and the adjusting ball, thereby ensuring that the suction needle can perform accurate sampling operations on the lesion position.

[0022] 4. The present invention cooperates with the negative pressure monitoring device and the external negative pressure extraction device. When an abnormal negative pressure value is detected, the negative pressure extraction device suspends operation, and the pneumatic device adjusts the gas pressure between the piston disk and the mounting block to force the needle head of the suction needle to move into the interior of the mounting tube, and at the same time adjusts the ball deflection to seal the outlet end of the mounting tube; then, the pneumatic device transports gas to the interior of the mounting tube, and uses the gas pressure to push the sample blocked in the suction needle or the extraction component, allowing it to smoothly enter the negative pressure extraction device, thereby effectively solving the problem of puncture needle blockage. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a schematic diagram of the structure of the puncture assembly of the present invention; Figure 2 It is a schematic diagram of the explosion structure of the piercing assembly of the present invention; Figure 3 It is a structural schematic diagram of the guide assembly of the present invention; Figure 4 It is a schematic diagram of the internal structure of the installation tube of the present invention; Figure 5 It is a structural schematic diagram of the extraction component of the present invention; Figure 6 It is a schematic diagram of the structure of the sampling assembly of the present invention; Figure 7 It is a schematic diagram of the structure of the suction needle of the present invention; Figure 8 It is a connection schematic diagram of the transmission member of the present invention; Fig. 9 This is a schematic diagram of the operation principle of the transmission member of the present invention; Fig.10 This is a first working schematic diagram of the adjusting ball of the present invention; Fig.11 A second working schematic diagram of the adjusting ball of the present invention; Fig.12 This is a third working schematic diagram of the adjusting ball of the present invention.

[0024] The accompanying drawings are marked as follows: 1. puncture assembly; 101. puncture outer sleeve; 102. puncture inner core; 103. connection part; 1031. fixing cap; 1032. fixing disk; 1033. mounting groove; 2. guide assembly; 201. mounting cylinder; 202. angle disk; 203. mounting block; 204. fitting part; 3. extraction assembly; 301. extraction interface; 302. avoidance channel; 303. connecting hose; 4. sampling assembly; 401. piston disk; 402. suction needle; 4021. needle tube; 4022. needle head; 4023. oblique hole; 5. steering assembly; 501. adjusting ball; 502. through groove; 503. transmission part; 5031. connecting shaft; 5032. traction rope; 5033. rotating shaft; 5034. rotating block; 6. pneumatic channel; 7. pneumatic interface. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0026] Embodiment 1 Reference Figure 1 to Figure 2 As shown, a tumor cell medical inspection sampling device includes a puncture component 1, which includes a puncture outer sleeve 101 with an oblique structure, a puncture inner core 102 with a pointed tip passing through the puncture outer sleeve 101, and a connecting portion 103 for docking with the puncture inner core 102 is provided on the top of the puncture outer sleeve 101.

[0027] During the CT-guided biopsy, the patient is first scanned with computed tomography (CT) to identify the location of the lesion. Subsequently, the CT scan data is analyzed using image processing software to assist in determining the best puncture point and mark the corresponding position on the patient's body surface to provide guidance for subsequent operations.

[0028] After the puncture point is determined, the puncture area is thoroughly disinfected and local anesthesia is performed to ensure the sterility of the operating environment and effectively reduce the patient's pain. According to the pre-planned puncture path and orientation, the puncture assembly 1 is accurately inserted into the lesion position. When the puncture assembly 1 reaches the predetermined depth, the puncture inner core 102 inside the puncture outer sleeve 101 is taken out, and the external negative pressure extraction device is docked with the connecting portion 103 of the outer sleeve, and the negative pressure extraction device is started. Through the puncture outer sleeve 101, the external negative pressure extraction device can perform negative pressure extraction sampling on the lesion.

[0029] It should be noted that the use of an external negative pressure extraction device for biopsy sampling is a prior art and will not be described in detail here.

[0030] After the biopsy sampling is completed, the puncture core 102 is first returned to its original position, and then the puncture assembly 1 is smoothly pulled out from the patient's body. Finally, the puncture area is properly covered with a sterile dressing to reduce the risk of infection and promote wound healing.

[0031] Embodiment 2 Although the above-mentioned device can perform the function of biopsy sampling through the negative pressure mechanism, it is inevitable that critical vascular structures and important organs will be encountered in the process of the puncture needle penetrating human tissue. These blood vessels and organs are not allowed to be touched by the puncture needle due to their high physiological sensitivity and functional necessity. Once the puncture operation accidentally damages such tissues, it is very likely to cause serious medical complications such as pneumothorax, vascular rupture, and even organ failure. Faced with insurmountable obstacles of important tissues or organs in the puncture path, clinicians are often forced to find alternative puncture paths. However, in actual operation scenarios, there is often a lack of ideal alternative paths. This limitation directly restricts the effective implementation of the puncture biopsy operation, and thus constitutes a significant obstacle to the smooth achievement of the treatment goal. In view of this, improvements are made on the basis of Example 1.

[0032] Reference Figures 1 to 11 As shown, a tumor cell medical test sampling device includes a puncture component 1 and a guide component 2 adapted thereto.

[0033] The guide assembly 2 comprises a mounting cylinder 201 , inside of which is provided a sampling assembly 4 movably arranged along its axial direction, and at the bottom of the mounting cylinder 201 is provided a steering assembly 5 for adjusting the direction of the sampling assembly 4 .

[0034] The steering assembly 5 includes an adjusting ball 501 arranged at the bottom of the mounting tube 201. A through slot 502 is provided through the adjusting ball 501. A transmission member 503 for driving the adjusting ball 501 to deflect is provided on the outer side of the adjusting ball 501. The transmission member 503 and the through slot 502 are in a mutually perpendicular state.

[0035] The sampling component 4 includes a piston disk 401 movably connected to the inner wall of the mounting cylinder 201, an extraction component 3 is provided at the end of the piston disk 401 away from the steering component 5, and a suction needle 402 is provided at the end of the piston disk 401 facing the steering component 5. After the adjustment ball 501 is deflected, when the suction needle 402 extends out of the mounting cylinder 201 through the through groove 502, the end of the suction needle 402 away from the piston disk 401 is deflected synchronously.

[0036] Reference Figures 3 to 7 As shown, a mounting block 203 is provided at one end of the mounting cylinder 201 away from the adjusting ball 501, and a pneumatic channel 6 connected to the mounting cylinder 201 is opened on the mounting block 203. A pneumatic interface 7 connected to the pneumatic channel 6 is provided on the outer side of the mounting block 203. By adjusting the gas flow direction in the pneumatic channel 6, the gap between the piston disk 401 and the mounting block 203 is controlled, and the piston disk 401 is reciprocated along the axial direction of the mounting cylinder 201.

[0037] A pneumatic device is provided on the outside of the installation cylinder 201, and the pneumatic device is connected to the pneumatic interface 7. The pneumatic device delivers gas to the inside of the installation cylinder 201 through the pneumatic interface 7, or extracts gas from the inside of the installation cylinder 201 through the pneumatic interface 7. The pneumatic device delivers gas to the installation cylinder 201 or extracts gas, which belongs to the prior art and will not be described in detail here.

[0038] When the pneumatic device delivers gas to the inside of the mounting cylinder 201 through the pneumatic interface 7, the gas enters the area between the piston disc 401 and the mounting block 203 through the pneumatic channel 6, causing the pressure in the area to increase, forcing the piston disc 401 to drive the suction needle 402 to move in the direction of the adjusting ball 501.

[0039] When the pneumatic device sucks the gas inside the mounting cylinder 201 through the pneumatic interface 7, the gas between the piston disk 401 and the mounting block 203 enters the inside of the pneumatic device through the pneumatic channel 6, and the pressure between the piston disk 401 and the mounting block 203 gradually decreases, forcing the piston disk 401 to drive the suction needle 402 to move away from the adjusting ball 501.

[0040] Reference Figures 3 to 9 As shown, the transmission member 503 includes a connecting shaft 5031 symmetrically arranged on the adjusting ball 501 , the connecting shaft 5031 is rotatably connected to the mounting cylinder 201 , and the straight line formed by the two connecting shafts 5031 and the through slot 502 are in a mutually perpendicular state.

[0041] A traction rope 5032 is wound around the two connecting shafts 5031 . The other ends of the two traction ropes 5032 are commonly connected to a rotating shaft 5033 . The rotating shaft 5033 is arranged inside the mounting block 203 . A rotating block 5034 is arranged at one end of the rotating shaft 5033 that passes through the mounting block 203 .

[0042] The rotating block 5034 synchronously drives the rotating shaft 5033 to rotate during the rotation process. When the rotating shaft 5033 rotates, the traction rope 5032 is reeled in and unreeled. The rotating shaft 5033 drives the adjusting ball 501 to rotate through the traction rope 5032, thereby adjusting the deflection direction of the suction needle 402.

[0043] It should be noted that the rotating shaft 5033 is rotatably connected to the mounting block 203, and a damper is provided at the connection between the rotating shaft 5033 and the mounting block 203, so that the rotating shaft 5033 is in a static state when there is no strong external force interference, thereby preventing the adjusting ball 501 from malfunctioning when the suction needle 402 is performing a sampling operation. Preventing malfunction of the rotating shaft 5033 by installing a damper is a prior art and will not be described in detail here.

[0044] The mounting cylinder 201 is provided with a traction channel for the traction rope 5032 to move.

[0045] Reference Figures 8 to 9 As shown, the two traction ropes 5032 distributed on the rotating shaft 5033 have their own characteristics in their winding methods.

[0046] The first traction rope 5032 is wound around the rotating shaft 5033 in a clockwise direction, and the winding direction between the first traction rope 5032 and the connecting shaft 5031 is counterclockwise.

[0047] The second traction rope 5032 is wound around the rotating shaft 5033 in a counterclockwise direction, and the winding direction between the second traction rope 5032 and the connecting shaft 5031 is clockwise.

[0048] The first traction rope 5032 is set as rope A, and the second traction rope 5032 is set as rope B (see Fig. 9 as shown).

[0049] When the rotating shaft 5033 rotates clockwise, the connection portion 103 between the rotating shaft 5033 and the rope A is in an unwinding state, and the connection portion 103 between the connecting shaft 5031 and the rope A is in a reeling state; conversely, the connection portion 103 between the rotating shaft 5033 and the rope B is in a reeling state, and the connection portion 103 between the connecting shaft 5031 and the rope B is in an unwinding state.

[0050] When the rotating shaft 5033 rotates counterclockwise, the connection portion 103 between the rotating shaft 5033 and the rope A is in a reeled state, while the connection portion 103 between the connecting shaft 5031 and the rope A is in an unreeled state; conversely, the connection portion 103 between the rotating shaft 5033 and the rope B is in an unreeled state, while the connection portion 103 between the connecting shaft 5031 and the rope B is in a reeled state.

[0051] by Figure 8 and Fig. 9 For example, when the rotating block 5034 drives the rotating shaft 5033 to rotate clockwise, the rotating shaft 5033 synchronously drives the connecting shaft 5031 to rotate clockwise through the traction rope 5032, thereby driving the adjusting ball 501 to deflect in the clockwise direction; when the rotating block 5034 drives the rotating shaft 5033 to rotate clockwise, the rotating shaft 5033 synchronously drives the connecting shaft 5031 to rotate counterclockwise through the traction rope 5032, thereby driving the adjusting ball 501 to deflect in the counterclockwise direction. The specific adjustment direction is adjusted according to the specific location of the lesion and the personal habits of the physician during actual use.

[0052] Reference Figures 3 to 7 As shown, the extraction assembly 3 includes a connecting hose 303 arranged on the piston disk 401 , the connecting hose 303 is connected to the suction needle 402 , and one end of the connecting hose 303 away from the piston disk 401 is connected to the mounting block 203 .

[0053] One end of the connecting hose 303 is fixedly connected to the piston disc 401 , and one end of the connecting hose 303 is fixedly connected to the mounting block 203 .

[0054] An escape passage 302 communicating with the connecting hose 303 is provided inside the mounting block 203 , and an extraction interface 301 is provided at the end of the escape passage 302 .

[0055] Reference Figures 2 to 6 As shown, the connecting portion 103 includes a fixing cap 1031 arranged at the end of the puncture outer sleeve 101, and a mounting groove 1033 is provided at one end of the fixing cap 1031 away from the puncture outer sleeve 101. A fixing plate 1032 is provided on the outer side of the fixing cap 1031, and an angle indicating groove is provided on the fixing plate 1032.

[0056] After the installation tube 201 enters the puncture outer sleeve 101, the angle disk 202 on the installation tube 201 is adapted to the installation groove 1033. By controlling the angle between the angle disk 202 and the angle indicating groove, the rotation angle of the adjustment ball 501 after deflection can be controlled, ensuring that the suction needle 402 can perform accurate sampling operations on the lesion position, thereby achieving accuracy in the sampling process.

[0057] An angle plate 202 is provided between the mounting tube 201 and the mounting block 203 , and the angle plate 202 is matched with the mounting groove 1033 .

[0058] It should be noted that: in this example, after the angle disc 202 and the mounting groove 1033 are connected, there is damping between the angle disc 202 and the mounting groove 1033, so that although the angle disc 202 can rotate in the mounting groove 1033, when the angle disc 202 is not interfered by a strong external force, it is in a static state, so as to avoid the installation cylinder 201 from malfunctioning when the suction needle 402 is performing a sampling operation. Preventing malfunctioning by setting damping between the two components is a prior art and will not be described in detail here.

[0059] When the adjusting ball 501 is in the first working state, the through groove 502 on the adjusting ball 501 and the piston plate 401 are in a mutually perpendicular state (specifically, Fig.10 as shown).

[0060] When the adjusting ball 501 is in the second working state, the through groove 502 on the adjusting ball 501 and the piston plate 401 are in a staggered state (specifically, Fig.11 as shown).

[0061] It should be noted that: initially, the adjusting ball 501 is in the first working state, the needle head 4022 of the suction needle 402 is located inside the through slot 502, and when the adjusting ball 501 is deflected, the needle head 4022 of the suction needle 402 will not leave the through slot 502.

[0062] During use, after the patient completes a CT scan, if the lesion location is blocked by the body's vascular structure or bones, the traditional puncture needle cannot directly act on the lesion location.

[0063] The CT scan data is analyzed and sorted using image processing software, and a non-direct puncture needle insertion path is adopted, that is, the puncture component 1 is first guided to the edge of the lesion, and then the guide component 2 performs puncture sampling operations on the lesion position.

[0064] After determining the needle insertion path, image processing software is used to assist in determining the optimal needle insertion point, and marking is made on the corresponding position on the patient's body surface to provide guidance for subsequent operations; the puncture area is then disinfected and local anesthesia is performed to ensure the sterility of the operating environment and reduce the patient's pain.

[0065] During puncture, first use the puncture component 1 to pierce the human body at a certain needle insertion angle, and control the needle insertion depth to ensure that the end of the puncture outer sleeve 101 away from the connecting part 103 is at the edge of the lesion location, then take out the puncture inner core 102 in the puncture outer sleeve 101, and insert the installation tube 201 into the puncture outer sleeve 101. At this time, the angle disk 202 on the installation tube 201 and the installation groove 1033 on the fixing cap 1031 are in a docking state.

[0066] It should be noted that during the puncture biopsy sampling process, the entire process is guided by CT images so that the lesion area can be sampled more accurately.

[0067] It should be noted that after the end of the puncture outer sleeve 101 away from the fixing cap 1031 reaches a predetermined depth, a fixing frame is set on the outside of the puncture outer sleeve 101 by medical tape to ensure that the puncture outer sleeve 101 will not malfunction when the guide assembly 2 punctures and samples the lesion.

[0068] After the angle disk 202 and the fixing cap 1031 are docked, the rotation angle of the adjusting ball 501 after deflection, that is, the angle between the rotating shaft 5033 and the angle indicating groove, can be controlled by rotating the angle between the angle disk 202 and the angle indicating groove, thereby ensuring that after the adjusting ball 501 is deflected, the suction needle 402 can perform accurate sampling operations on the lesion position, thereby achieving the accuracy of the sampling process.

[0069] After adjusting the angle between the angle disk 202 and the angle indicating groove, the rotating block 5034 is turned, and the rotating block 5034 drives the rotating shaft 5033 to rotate. During the rotation of the rotating shaft 5033, the connecting shaft 5031 is driven by the traction rope 5032 to drive the adjusting ball 501 to deflect, so that the adjusting ball 501 is in the second working state. The deflection angle of the adjusting ball 501 is autonomously adjusted according to the number of rotations or the rotation angle of the rotating block 5034.

[0070] It should be noted that: after determining the needle insertion path, when the installation tube 201 has not yet been inserted into the puncture outer sleeve 101, the medical staff can directly use the transmission member 503 to adjust the deflection angle of the adjustment ball 501 outside the body according to the pre-set angle. In this way, after the installation tube 201 is inserted into the puncture outer sleeve 101, it is only necessary to adjust the angle between the angle disk 202 and the angle indicating groove.

[0071] Then, the external pneumatic device is connected to the pneumatic interface 7, and the pneumatic device transmits gas to the inside of the installation cylinder 201 through the pneumatic interface 7, so that the pressure between the piston plate 401 and the installation block 203 increases, forcing the piston plate 401 to drive the suction needle 402 to move in the direction of the adjustment ball 501. Since the needle head 4022 of the suction needle 402 is located inside the through groove 502 in the initial state, and the suction needle 402 has elasticity and toughness, when the piston plate 401 drives the suction needle 402 to move in the direction of the adjustment ball 501, the suction needle 402 is guided by the through groove 502 to extend out of the through groove 502 in a deflected state (see for details). Fig.11 As shown), the suction needle 402 can avoid important tissues of the human body and the needle head 4022 can be accurately inserted into the lesion, avoiding inadvertent damage to important tissues of the human body during puncture, thereby avoiding the occurrence of medical accidents.

[0072] After the needle head 4022 is inserted into the lesion, the external negative pressure extraction device is docked with the extraction interface 301 on the mounting block 203, and the negative pressure extraction device is started. The external negative pressure extraction device is docked through the extraction interface 301 to perform negative pressure extraction sampling on the lesion. The sample is drawn from the lesion through the needle 402, the connecting hose 303 and the avoidance channel 302 and finally enters the negative pressure extraction device. Medical staff can diagnose the patient's condition by testing the sample inside the negative pressure extraction device.

[0073] After sampling is completed, the gas between the piston disk 401 and the mounting block 203 is sucked through the pneumatic device, forcing the piston disk 401 to drive the suction needle 402 to move away from the adjusting ball 501. When the piston disk 401 moves, the suction needle 402 is pulled, so that the needle head 4022 of the suction needle 402 moves to the inside of the mounting tube 201. Then the guide assembly 2 is taken out, and the puncture inner core 102 is returned to its position. Finally, the puncture assembly 1 is smoothly pulled out of the patient's body.

[0074] Embodiment 3 Although the above device can drive the adjustment ball 501 to deflect through the transmission member 503, thereby effectively guiding the suction needle 402 to avoid key parts of the human body during the biopsy sampling process to prevent the occurrence of accidental puncture accidents, the puncture needle still faces the risk of blockage during the sampling process, and such blockage is often difficult to detect in time. The blockage phenomenon not only significantly increases the difficulty of tissue aspiration, but also, when the doctor tries to increase the negative pressure intensity to relieve the blockage, it is very easy to cause damage to the surrounding tissue due to excessive operation, which undoubtedly further increases the complexity of treatment and increases potential clinical risks. In view of this, improvements are made on the basis of Example 2.

[0075] Reference Figures 4 to 12As shown, a fitting portion 204 is provided at one end of the installation tube 201 away from the installation block 203 , and the fitting portion 204 covers the outer wall of the adjustment ball 501 . The length of the fitting portion 204 is greater than the radius of the through slot 502 .

[0076] The transmission member 503 drives the adjusting ball 501 to deflect, and when the through slot 502 on the adjusting ball 501 is in a parallel state with the piston plate 401 , the fitting portion 204 completely blocks the through slot 502 on the adjusting ball 501 .

[0077] Reference Figure 7 As shown, the suction needle 402 includes a needle tube portion 4021 connected to the piston disk 401 , the needle tube portion 4021 is connected to the connecting hose 303 , and the needle tube portion 4021 is adapted to the through groove 502 .

[0078] A needle head 4022 is disposed at one end of the needle tube portion 4021 away from the piston disk 401 . An array of oblique holes 4023 are disposed on the outer side of the needle head 4022 . The oblique holes 4023 are communicated with the needle tube portion 4021 .

[0079] The oblique hole 4023 is located on the outer wall of the needle head 4022 to prevent the needle head 4022 from being blocked by some tissues after entering the lesion.

[0080] When the adjusting ball 501 is in the third working state, the through groove 502 on the adjusting ball 501 is in a parallel state with the piston plate 401 (specifically, Fig.12 as shown).

[0081] In this embodiment, the external negative pressure extraction device is provided with a negative pressure monitoring device. Since the negative pressure generated when the negative pressure extraction device extracts the sample is in a set state, the value of the negative pressure monitoring device is detected to determine whether the extraction component 3 or the sampling component 4 is blocked.

[0082] When the value on the negative pressure monitoring device is greater than the set value, it indicates that when the negative pressure extraction device is sucking the sample, the extraction component 3 or the sampling component 4 is blocked, which causes the value on the negative pressure monitoring device to be greater than the set value.

[0083] When the extraction component 3 or the sampling component 4 is blocked, the negative pressure extraction device suspends operation and uses a pneumatic device to suck the gas between the piston disk 401 and the mounting block 203, forcing the piston disk 401 to drive the needle head 4022 of the suction needle 402 to move into the inside of the mounting tube 201, and the needle head 4022 is out of contact with the through groove 502.

[0084] Then, the rotating block 5034 is turned, and the rotating block 5034 drives the adjusting ball 501 to deflect through the rotating shaft 5033 and the traction rope 5032, so that the adjusting ball 501 is in the third working state (specifically, Fig.12As shown), when the through slot 502 on the adjusting ball 501 is in parallel with the piston disk 401, the fitting portion 204 blocks the through slot 502 on the adjusting ball 501, that is, the outlet end of the mounting cylinder 201 is blocked by the adjusting ball 501.

[0085] After the adjusting ball 501 is in the third working state, the negative pressure extraction device is started again, and the pneumatic device simultaneously delivers gas to the inside of the installation cylinder 201, forcing the piston disk 401 to drive the suction needle 402 to move in the direction of the adjusting ball 501. Since the outlet end of the installation cylinder 201 is blocked by the adjusting ball 501, the gas between the piston disk 401 and the adjusting ball 501 enters the suction needle 402 through the inclined hole 4023 after being pressurized, and pushes the sample blocked in the suction needle 402 or the extraction component 3, so that the sample can smoothly enter the negative pressure extraction device, thereby avoiding the phenomenon that the puncture needle is difficult to detect in time and difficult to handle after being blocked.

[0086] Embodiment 4 The present invention also provides a sampling method of a tumor cell medical test sampling device, the sampling method comprising the following steps: S1. Use CT technology to perform a whole-body or local scan of the patient to identify the location of the lesion. By analyzing the CT scan data, use image processing software to assist in determining the optimal needle insertion point, and make a mark on the corresponding position on the patient's body surface to provide guidance for subsequent operations; S2. After the puncture point is determined, the puncture area is disinfected and local anesthesia is performed to ensure the sterility of the operating environment and relieve the patient's pain; S3. According to the pre-planned puncture path and orientation, the puncture assembly 1 is guided to the edge of the lesion. After reaching the predetermined depth, the puncture core 102 inside the puncture outer sleeve 101 is removed to create the necessary space for subsequent sampling operations; S4. Insert the guide assembly 2 into the puncture outer sleeve 101, adjust the angle of the adjustment ball 501 through the transmission member 503, ensure that the through slot 502 on the guide assembly 2 is aligned with the lesion position, stimulate the suction needle 402, and guide the suction needle 402 through the through slot 502 to perform biopsy sampling on the lesion; S5. After the biopsy sampling is completed, the guide assembly 2 is first removed, and then the puncture core 102 is returned to its original position, and finally the puncture assembly 1 is smoothly pulled out of the patient's body; S6. Properly cover the puncture area with a sterile dressing to reduce the risk of infection and promote wound healing.

[0087] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A tumor cell medical test sampling device, characterized in that: It comprises a puncture component (1) and a guide component (2) adapted thereto; The guide assembly (2) comprises a mounting tube (201), a sampling assembly (4) movably arranged along its axial direction is provided inside the mounting tube (201), and a steering assembly (5) for adjusting the direction of the sampling assembly (4) is provided at the bottom of the mounting tube (201); The steering assembly (5) comprises an adjusting ball (501) arranged at the bottom of the mounting cylinder (201), a through slot (502) penetrating the adjusting ball (501), a transmission member (503) for driving the adjusting ball (501) to deflect is arranged on the outer side of the adjusting ball (501), and the transmission member (503) and the through slot (502) are in a mutually perpendicular state; The sampling assembly (4) comprises a piston disc (401) movably connected to the inner wall of the mounting tube (201); an extraction assembly (3) is provided at one end of the piston disc (401) away from the steering assembly (5); and a suction needle (402) is provided at one end of the piston disc (401) facing the steering assembly (5); after the adjustment ball (501) is deflected, when the suction needle (402) extends out of the mounting tube (201) through the through slot (502), the end of the suction needle (402) away from the piston disc (401) is deflected synchronously.

2. The tumor cell medical testing sampling device according to claim 1, characterized in that: A mounting block (203) is provided at one end of the mounting cylinder (201) away from the adjusting ball (501); a pneumatic channel (6) communicating with the mounting cylinder (201) is provided on the mounting block (203); a pneumatic interface (7) connected to the pneumatic channel (6) is provided on the outer side of the mounting block (203); and the gap between the piston disc (401) and the mounting block (203) is controlled by adjusting the flow direction of gas in the pneumatic channel (6), thereby achieving reciprocating movement of the piston disc (401) along the axial direction of the mounting cylinder (201).

3. The tumor cell medical testing sampling device according to claim 2, characterized in that: The transmission member (503) comprises a connecting shaft (5031) symmetrically arranged on the adjusting ball (501), the connecting shaft (5031) being rotatably connected to the mounting cylinder (201), and the straight line formed by the two connecting shafts (5031) and the through slot (502) being in a mutually perpendicular state; A traction rope (5032) is wound around each of the two connecting shafts (5031); the other ends of the two traction ropes (5032) are commonly connected to a rotating shaft (5033); the rotating shaft (5033) is arranged inside the mounting block (203); and a rotating block (5034) is provided at one end of the rotating shaft (5033) that passes through the mounting block (203); The installation cylinder (201) is provided with a traction channel for the traction rope (5032) to move.

4. The tumor cell medical testing sampling device according to claim 3, characterized in that: The two traction ropes (5032) distributed on the rotating shaft (5033) have their own characteristics in winding manner; The first traction rope (5032) is wound around the rotating shaft (5033) in a clockwise direction, while the winding direction between the first traction rope (5032) and the connecting shaft (5031) is counterclockwise; The second traction rope (5032) is wound around the rotating shaft (5033) in a counterclockwise direction, while the winding direction between the second traction rope (5032) and the connecting shaft (5031) is clockwise.

5. The tumor cell medical testing sampling device according to claim 2, characterized in that: The extraction assembly (3) comprises a connecting hose (303) arranged on the piston disc (401), the connecting hose (303) being in communication with the suction needle (402), and one end of the connecting hose (303) away from the piston disc (401) being connected to the mounting block (203); An escape channel (302) communicating with the connecting hose (303) is provided inside the installation block (203), and an extraction interface (301) is provided at the end of the escape channel (302).

6. The tumor cell medical testing sampling device according to claim 5, characterized in that: The suction needle (402) comprises a needle tube portion (4021) connected to the piston disk (401), the needle tube portion (4021) is in communication with the connecting hose (303), and the needle tube portion (4021) is adapted to the through groove (502); A needle head (4022) is provided at one end of the needle tube portion (4021) away from the piston disk (401), and an array of oblique holes (4023) are provided on the outside of the needle head portion (4022), and the oblique holes (4023) are connected to the needle tube portion (4021).

7. The tumor cell medical testing sampling device according to claim 6, characterized in that: The puncture assembly (1) comprises an outer puncture sleeve (101) with an oblique structure, a puncture inner core (102) provided with a pointed tip passing through the interior of the outer puncture sleeve (101), and a connecting portion (103) for docking with the puncture inner core (102) is provided at the top of the outer puncture sleeve (101).

8. The tumor cell medical testing sampling device according to claim 7, characterized in that: The connecting portion (103) comprises a fixing cap (1031) arranged at the end of the puncture outer sleeve (101), an end of the fixing cap (1031) away from the puncture outer sleeve (101) is provided with a mounting groove (1033), a fixing plate (1032) is arranged on the outer side of the fixing cap (1031), and an angle indicating groove is arranged on the fixing plate (1032); An angle plate (202) is provided between the mounting cylinder (201) and the mounting block (203), and the angle plate (202) is adapted to the mounting groove (1033).

9. The tumor cell medical testing sampling device according to claim 2, characterized in that: An end of the installation tube (201) away from the installation block (203) is provided with a fitting portion (204), the fitting portion (204) covers the outer wall of the adjustment ball (501), and the length of the fitting portion (204) is greater than the radius of the through slot (502).

10. A sampling method of the tumor cell medical test sampling device according to claim 8, characterized in that: The sampling method comprises the following steps: S1. Use CT technology to perform a whole-body or local scan of the patient to identify the location of the lesion. By analyzing the CT scan data, use image processing software to assist in determining the optimal needle insertion point, and make a mark on the corresponding position on the patient's body surface to provide guidance for subsequent operations; S2. After the puncture point is determined, the puncture area is disinfected and local anesthesia is performed to ensure the sterility of the operating environment and relieve the patient's pain; S3. According to the pre-planned puncture path and orientation, the puncture assembly (1) is guided to the edge of the lesion. After reaching the predetermined depth, the puncture core (102) inside the puncture outer sleeve (101) is removed to create the necessary space for subsequent sampling operations; S4. Insert the guide assembly (2) into the puncture outer sleeve (101), adjust the angle of the adjustment ball (501) through the transmission member (503), ensure that the through slot (502) on the guide assembly (2) is aligned with the lesion position, stimulate the suction needle (402), and guide the suction needle (402) through the through slot (502) to perform biopsy sampling on the lesion; S5. After the biopsy sampling is completed, the guide assembly (2) is first removed, and then the puncture core (102) is returned to its original position, and finally the puncture assembly (1) is smoothly pulled out of the patient's body; S6. Properly cover the puncture area with a sterile dressing to reduce the risk of infection and promote wound healing.

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