Intelligent culture medium preparation device and preparation machine

Through the peristaltic pump, bypass tube, chemical electronic scale and GPS locator of the intelligent culture medium configuration device, the problem of safety risks of traditional culture medium configuration devices is solved, and the confidentiality of drug liquid ratio and the safe operation of equipment are achieved. , improve competitiveness and use safety.

CN119236787APending Publication Date: 2025-01-03RUBBER RES INST CHINESE ACADEMY OF TROPICAL AGRI SCI
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Patent Information

Application Number
CN202411440536.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-15
Publication Date
2025-01-03

AI Technical Summary

Technical Problem

Traditional culture medium configuration devices have safety risks when delivering agents, and the mixing ratios obtained by external personnel may lead to the replication of the real formula, affecting competitiveness.

Method used

An intelligent culture medium configuration device was designed, using a peristaltic pump and bypass tube combined with a chemical electronic scale and an alarm system. It automatically calibrates and stirs through the random discharge and the PH meter in the stirring chamber to ensure that the ratio of the medicine liquid is kept confidential and passes through GPS locator prevents the device from operating in unauthorized areas.

Benefits of technology

It effectively protects the safety of the drug solution ratio, prevents the formula from being copied, improves the safety and competitiveness of use, and reduces the risk of theft and misuse through automation and real-time monitoring.

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Abstract

The intelligent culture medium preparation device comprises a main machine body and a stirring bin formed in the top of the main machine body, a discharging bin is formed below the stirring bin, a liquid discharging unit is arranged at the bottom of the stirring bin, a medicament cavity is formed in the front side wall of the main machine body, and a medicament box door is rotationally arranged at a cavity opening of the medicament cavity; a plurality of medicine supply units are arranged in the medicine cavity, and a first side cavity is formed in one side of the main machine body. According to the device, chemicals in a plurality of chemical barrels are pumped into a liquid collector through a peristaltic pump, then the premixed chemicals are pumped into a stirring bin through a pump body, in order to protect the real chemical preparation proportion, chemical stock solution can be discharged randomly through a bypass pipe during chemical preparation, the stock solution is discharged into a waste box through a seepage pipe, and the chemical preparation efficiency is improved. Therefore, the proportion of the liquid medicine in the stirring bin is kept confidential, reverse calculation is prevented, and the safe use effect is improved.
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Description

Technical Field

[0001] The present invention relates to the technical field of culture medium configuration, and in particular to an intelligent culture medium configuration device and a configuration machine. Background Art

[0002] Culture medium refers to a nutrient matrix composed of different nutrients for the growth and reproduction of microorganisms, plants or animals (or tissues). It generally contains several major types of substances, such as carbohydrates, nitrogen-containing substances, inorganic salts (including trace elements), vitamins and water. Culture medium is not only the basic substance for providing cell nutrition and promoting cell proliferation, but also the living environment for cell growth and reproduction.

[0003] Traditional culture medium preparation devices deliver various drugs in a certain proportion, and the proportion of various components in the mixed solution can be reversed. This poses a security risk and may lead to the leakage of technical secrets. If the mixing ratio is obtained by outsiders, the real formula may be copied, affecting competitiveness. Summary of the invention

[0004] 1. Technical issues to be solved

[0005] In view of the deficiencies in the prior art, the present invention provides an intelligent culture medium configuration device and a configuration machine, which solve the problems raised in the above-mentioned background technology.

[0006] (II) Technical solution

[0007] To achieve the above objectives, the present invention is implemented through the following technical solutions: an intelligent culture medium configuration device and a configuration machine, comprising a main body, a stirring bin opened on the top of the main body, a discharge bin opened below the stirring bin, a drainage unit arranged at the bottom of the stirring bin, a medicine cavity opened on the front side wall of the main body, a medicine box door rotatably arranged at the cavity mouth of the medicine cavity, a plurality of medicine supply units arranged inside the medicine cavity, a first side cavity opened on one side of the main body, a first side box door rotatably installed at the outlet of the first side cavity, a medicine pump unit fixedly installed inside the first side cavity, the medicine supply unit and the medicine pump unit are connected by an infusion tube, a bypass tube is arranged on the infusion tube, and the other end of the bypass tube is connected to the drainage unit.

[0008] Preferably, the medicine pump unit includes a controller and a heat dissipation device, a plurality of peristaltic pumps are fixedly mounted on the first side box door, the infusion tube is passed through the inside of the peristaltic pump, a liquid collector is fixedly mounted on the top wall of the first side cavity, and the plurality of infusion tubes are connected to the liquid collector, a medicine delivery pump body is fixedly mounted on the first side box door, the output end of the medicine delivery pump body is fixedly connected to the medicine delivery tube, and the other end of the medicine delivery tube is located inside the stirring chamber

[0009] Preferably, the medicine supply unit comprises an electronic medicine scale and a medicine barrel placed on the electronic medicine scale, a plurality of warning lights are fixedly installed inside the medicine cavity, and an alarm is fixedly installed on the top of the main body.

[0010] Preferably, after setting the alarm upper and lower limits, the current alarm value calls a random value between the upper and lower limits. The electronic scale for medicine will alarm when the weighing value is less than the current alarm value, and the corresponding electronic lock on the medicine box door will control the corresponding medicine box door to open, and the corresponding warning light will light up to prevent incorrect drug addition. After the drug addition is completed, the alarm value will re-call a new random value as the next alarm value.

[0011] Preferably, the drainage unit includes a seepage pipe connected to the bottom of the mixing bin, the lower end of the seepage pipe is connected to a waste box, the waste box is located inside the discharge bin, the seepage pipe is provided with a first valve, the bypass pipe is connected to the seepage pipe, the bypass pipe is provided with a control valve, and the raw liquid is randomly discharged into the waste box through the seepage pipe, the side wall of the waste box is connected to a sewage pipe, the sewage pipe is provided with a second valve, and also includes a cleaning pipe, one end of the cleaning pipe is connected to an external water source, and the other end is located in the mixing bin, and an ultrasonic liquid level sensor is fixedly installed at the top opening of the mixing bin.

[0012] Preferably, a motor is fixedly mounted on the top wall of the discharge bin, a rotating block is fixedly connected to the output end of the motor, the rotating block is movably arranged in the stirring bin, an offset agitator is fixedly connected to the top of the rotating block, a heating pipe is fixedly mounted on the bottom wall of the stirring bin, a drain pipe is connected to the bottom of the stirring bin, a diaphragm pump is connected to the other end of the drain pipe, and the diaphragm pump is located inside the discharge bin.

[0013] Preferably, the medicine barrel includes a pH barrel and a culture medium raw material barrel, a pH meter is fixedly installed on the top of the main body, and the detection end of the pH meter is located inside the stirring chamber.

[0014] Preferably, a control panel is fixedly mounted on the side wall of the main body, and a GPS locator is fixedly mounted on the top of the main body.

[0015] Preferably, the medicine chamber is divided into a normal temperature chamber and a cold storage chamber, an insulating layer is fixedly connected to the inner wall of the cold storage chamber, and a ceramic refrigeration sheet is fixedly installed inside the cold storage chamber.

[0016] (III) Beneficial effects

[0017] The present invention provides an intelligent culture medium configuration device and configuration machine, which have the following beneficial effects:

[0018] 1. In the present invention, the medicines in multiple medicine barrels are pumped into a liquid collector through a peristaltic pump, and then the pre-mixed medicines are pumped into the mixing chamber through the pump body. In order to protect the actual dispensing ratio, the medicine stock solution will be randomly discharged through the bypass pipe during dispensing, and the stock solution will be discharged into the waste box through the seepage pipe. In this way, the medicine liquid ratio in the mixing chamber is kept confidential, which can prevent reverse calculation and improve the safety of use.

[0019] 2. In the present invention, after setting the alarm upper limit and lower limit, the current alarm value calls a random value between the upper limit and the lower limit, and the electronic scale for medicine alarms when the weighing value is less than the current alarm value. After the addition of medicine is completed, the alarm value re-calls a new random value as the next alarm value. When the electronic scale for medicine detects that the weight of the medicine barrel is a random value between the upper limit and the lower limit, the alarm sounds an alarm, and the corresponding electronic lock on the medicine box door will control the corresponding medicine box door to open, and the corresponding warning light will light up to prevent incorrect addition of medicine.

[0020] 3. In the present invention, after the liquid preparation is completed, a pH meter is used to automatically calibrate the pH value; the sodium hydroxide and hydrochloric acid solutions in the pH barrel are used to configure the acid and alkali of the agent, and the motor is started to drive the rotating block and the agitator to rotate, and the mixed liquid in the stirring bin is stirred, and the preset pH value is aligned by titration while stirring.

[0021] 4. In the present invention, the liquid level is detected by an ultrasonic liquid level sensor when the machine is turned on. If it is not 0, if cleaning is not required, the prepared agent is selected on the interface of the control panel. If cleaning is required, automatic cleaning is performed, and the external water source supplies the cleaning liquid, which enters the mixing chamber through the cleaning pipe. If manual cleaning is selected, the drainage and cleaning actions are performed manually. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 This is a left-view stereoscopic structural diagram of an intelligent culture medium configuration device and configuration machine proposed by the present invention;

[0023] Figure 2 This is a front perspective structural diagram of an intelligent culture medium configuration device and configuration machine proposed by the present invention;

[0024] Figure 3 A top-down perspective structural diagram of an intelligent culture medium configuration device and configuration machine proposed by the present invention;

[0025] Figure 4 A cross-sectional stereoscopic structural diagram of an intelligent culture medium configuration device and configuration machine proposed by the present invention;

[0026] Figure 5 This is a rear perspective structural diagram of an intelligent culture medium configuration device and configuration machine proposed by the present invention;

[0027] Figure 6 for Figure 5 Enlarged structural diagram at point A.

[0028] In the figure: 1. main body; 101. mixing bin; 102. discharging bin; 103. medicine chamber; 1031. normal temperature chamber; 1032. cold storage chamber; 104. first side chamber; 2. rotating block; 3. agitator; 4. motor; 5. drainage pipe; 6. diaphragm pump; 7. seepage pipe; 8. waste box; 9. first valve; 10. second valve; 11. medicine barrel; 12. infusion tube; 13. peristaltic pump; 14. liquid collector; 15. medicine delivery pump body; 16. medicine electronic scale; 17. warning light; 18. medicine delivery pipe; 19. GPS locator; 20. pH meter; 21. ultrasonic liquid level sensor; 22. heating tube; 23. medicine box door; 24. first side box door; 25. control panel; 26. ceramic cooling plate; 27. controller; 28. alarm; 29. ​​bypass pipe. DETAILED DESCRIPTION

[0029] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0030] See also Figures 1 to 6 The present invention provides a technical solution: an intelligent culture medium configuration device and a configuration machine, comprising a main body 1, a stirring chamber 101 opened on the top of the main body 1, a discharge chamber 102 opened below the stirring chamber 101, a drainage unit arranged at the bottom of the stirring chamber 101, a medicine cavity 103 opened on the front side wall of the main body 1, a medicine box door 23 rotatably arranged at the cavity mouth of the medicine cavity 103, a plurality of medicine supply units arranged inside the medicine cavity 103, a first side cavity 104 opened on one side of the main body 1, a first side box door 24 rotatably installed at the outlet of the first side cavity 104, a medicine pump unit fixedly installed inside the first side cavity 104, the medicine supply unit and the medicine pump unit are connected through an infusion tube 12, a bypass tube 29 is arranged on the infusion tube 12, and the other end of the bypass tube 29 is connected to the drainage unit.

[0031] The medicine inside the medicine supply unit is pumped into the infusion tube 12 through the medicine pump unit, and then the medicine is transported to the liquid collector 14. Finally, the mixed medicine is transported to the stirring chamber 101 through the liquid collector 14. A bypass tube 29 is provided on the infusion tube 12 to randomly discharge part of the original liquid into the liquid discharge unit, thereby ensuring that the medicine liquid ratio inside the stirring chamber 101 is kept confidential, preventing it from being reversely calculated, and improving the safety of use.

[0032] The medicine pump unit includes a controller 27 and a heat dissipation device. A plurality of peristaltic pumps 13 are fixedly installed on the first side box door 24. The infusion tube 12 is passed through the inside of the peristaltic pump 13. A liquid collector 14 is fixedly installed on the top wall of the first side cavity 104. The plurality of infusion tubes 12 are connected to the liquid collector 14. A medicine delivery pump body 15 is fixedly installed on the first side box door 24. The output end of the medicine delivery pump body 15 is fixedly connected to a medicine delivery tube 18, and the other end of the medicine delivery tube 18 is located inside the stirring chamber 101. The medicines in the plurality of medicine barrels 11 are pumped into a liquid collector 14 through the peristaltic pump 13, and then the pre-mixed medicines are pumped into the stirring chamber 101 through the medicine delivery pump body 15.

[0033] The medicine supply unit includes a medicine electronic scale 16 and a medicine barrel 11 placed on the medicine electronic scale 16 . A plurality of warning lights 17 are fixedly installed inside the medicine cavity 103 , and an alarm 28 is fixedly installed on the top of the main body 1 .

[0034] After setting the alarm upper and lower limits, the current alarm value calls a random value between the upper and lower limits. The electronic pharmaceutical scale 16 will alarm when the weighing value is less than the current alarm value. At this time, the alarm 28 will sound, and the corresponding electronic lock on the medicine box door 23 will control the corresponding medicine box door 23 to open, and the corresponding warning light 17 will light up to prevent incorrect drug addition. After the drug addition is completed, the alarm value will re-call a new random value as the next alarm value.

[0035] The discharge unit includes a seepage pipe 7 connected to the bottom of the stirring chamber 101, the lower end of the seepage pipe 7 is connected to a waste box 8, the waste box 8 is located inside the discharge bin 102, a first valve 9 is arranged on the seepage pipe 7, a bypass pipe 29 is connected to the seepage pipe 7, a control valve is arranged on the bypass pipe 29, and the raw liquid is randomly discharged into the waste box 8 through the seepage pipe 7; in order to protect the actual dispensing ratio, the medicine raw liquid will be randomly discharged through the bypass pipe 29 during dispensing, and the raw liquid will be discharged into the waste box 8 through the seepage pipe 7, so as to ensure that the medicine liquid ratio inside the stirring chamber 101 is kept confidential, prevent reverse calculation, and improve the safety of use. A sewage pipe is provided on the side wall of the waste box 8, and a second valve 10 is provided on the sewage pipe, which also includes a cleaning pipe. One end of the cleaning pipe is connected to an external water source, and the other end is located in the mixing chamber 101. An ultrasonic liquid level sensor 21 is fixedly installed at the top opening of the mixing chamber 101. When the machine is turned on, the liquid level will be detected by the ultrasonic liquid level sensor 21. If it is not 0, if cleaning is not required, the prepared agent will be selected in the interface of the control panel 25. If cleaning is required, automatic cleaning will be performed, and the external water source will supply cleaning liquid, and the cleaning liquid will enter the mixing chamber 101 through the cleaning pipe. If manual cleaning is selected, the drainage and cleaning actions are performed manually.

[0036] A motor 4 is fixedly installed on the top wall of the discharge bin 102, and a rotating block 2 is fixedly connected to the output end of the motor 4. The rotating block 2 is movably arranged in the mixing bin 101, and an offset agitator 3 is fixedly connected to the top of the rotating block 2. By starting the motor 4, the rotating block 2 and the agitator 3 are driven to rotate, and the mixed liquid medicine inside the mixing bin 101 is stirred to promote the configuration process. A heating tube 22 is fixedly installed on the bottom wall of the mixing bin 101. When the configured medicine needs to be heated, the heating tube 22 is arranged to heat the mixed medicine inside the mixing bin 101. A discharge pipe 5 is connected to the bottom of the mixing bin 101, and a diaphragm pump 6 is connected to the other end of the discharge pipe 5. The diaphragm pump 6 is located inside the discharge bin 102. After completing the liquid preparation work, the diaphragm pump 6 is started to discharge the mixed medicine inside the mixing bin 101 through the discharge pipe 5.

[0037] The medicine barrel 11 includes a pH barrel and a culture medium raw material barrel. A pH meter 20 is fixedly installed on the top of the main body 1, and the detection end of the pH meter 20 is located inside the stirring chamber 101.

[0038] After the liquid preparation is completed, the pH meter 20 is used to automatically calibrate the pH value; the sodium hydroxide and hydrochloric acid solutions in the pH barrel are used to configure the acid and base of the reagent, and the motor 4 is started to drive the rotating block 2 and the stirrer 3 to rotate, and the mixed liquid in the stirring chamber 101 is stirred, and the preset pH value is aligned by titration while stirring.

[0039] A control panel 25 is fixedly installed on the side wall of the main body 1 to input instructions for various operations; a GPS locator 19 is fixedly installed on the top of the main body 1. When the position of the detection instrument is different from the authorized position, the machine stops working. By monitoring the position of the equipment in real time, the equipment can be prevented from operating in unauthorized areas, reducing the risk of theft or misuse, and certain pharmaceutical ingredients can be calculated and fine-tuned according to the latitude.

[0040] The medicine chamber 103 is divided into a normal temperature room 1031 and a cold storage room 1032. An insulating layer is fixedly connected to the inner wall of the cold storage room 1032, and a ceramic refrigeration plate 26 is fixedly installed inside the cold storage room 1032. When the medicine needs to be refrigerated, the ceramic refrigeration plate 26 starts to work, generates a temperature difference through electric current, and quickly reduces the temperature of the cold storage room 1032. At the same time, the presence of the insulating layer ensures that the heat exchange between the cold storage room and the outside world is minimized, thereby maintaining a constant low temperature environment.

[0041] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. The above embodiments and descriptions are only preferred examples of the present invention and are not intended to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. An intelligent culture medium configuration device and configuration machine, characterized in that: The invention comprises a main body (1), a stirring chamber (101) opened at the top of the main body (1), a discharge chamber (102) opened below the stirring chamber (101), a liquid discharge unit arranged at the bottom of the stirring chamber (101), a medicine chamber (103) opened on the front side wall of the main body (1), a medicine box door (23) rotatably arranged at the cavity opening of the medicine chamber (103), a plurality of medicine supply units arranged inside the medicine chamber (103), a first side chamber (104) opened on one side of the main body (1), a first side chamber door (24) rotatably installed at the outlet of the first side chamber (104), a medicine pump unit fixedly installed inside the first side chamber (104), the medicine supply unit and the medicine pump unit are connected via an infusion tube (12), a bypass tube (29) is arranged on the infusion tube (12), and the other end of the bypass tube (29) is connected to the liquid discharge unit.

2. The intelligent culture medium configuration device and configuration machine according to claim 1, characterized in that: The medicine pump unit comprises a controller (27) and a heat dissipation device. A plurality of peristaltic pumps (13) are fixedly mounted on the first side door (24). The infusion tube (12) is passed through the inside of the peristaltic pump (13). A liquid collector (14) is fixedly mounted on the top wall of the first side cavity (104). The plurality of infusion tubes (12) are connected to the liquid collector (14). A medicine delivery pump body (15) is fixedly mounted on the first side door (24). The output end of the medicine delivery pump body (15) is fixedly connected to a medicine delivery tube (18). The other end of the medicine delivery tube (18) is located inside the stirring chamber (101).

3. The intelligent culture medium configuration device and configuration machine according to claim 1, characterized in that: The medicine supply unit comprises an electronic medicine scale (16), a medicine barrel (11) placed on the electronic medicine scale (16), a plurality of warning lights (17) are fixedly installed inside the medicine cavity (103), and an alarm (28) is fixedly installed on the top of the main body (1).

4. The intelligent culture medium configuration device and configuration machine according to claim 3, characterized in that: After setting the alarm upper limit and lower limit, the current alarm value calls a random value between the upper limit and the lower limit. When the weighing value of the electronic medicine scale (16) is less than the current alarm value, an alarm is triggered, and the corresponding electronic lock on the medicine box door (23) controls the corresponding medicine box door (23) to open, and the corresponding warning light (17) is lit to prevent incorrect drug addition. After the drug addition is completed, the alarm value calls a new random value as the next alarm value.

5. The intelligent culture medium configuration device and configuration machine according to claim 1, characterized in that: The liquid discharge unit comprises a liquid seepage pipe (7) connected to the bottom of the stirring chamber (101); the lower end of the liquid seepage pipe (7) is connected to a waste box (8); the waste box (8) is located inside the discharge chamber (102); the liquid seepage pipe (7) is provided with a first valve (9); the bypass pipe (29) is connected to the liquid seepage pipe (7); the bypass pipe (29) is provided with a control valve; the original liquid is randomly discharged into the waste box (8) through the liquid seepage pipe (7); a sewage pipe is connected to the side wall of the waste box (8); the sewage pipe is provided with a second valve (10); and the liquid seepage unit further comprises a cleaning pipe; one end of the cleaning pipe is connected to an external water source; the other end is located inside the stirring chamber (101); an ultrasonic liquid level sensor (21) is fixedly installed at the top opening of the stirring chamber (101).

6. The intelligent culture medium configuration device and configuration machine according to claim 1, characterized in that: A motor (4) is fixedly mounted on the top wall of the discharge bin (102); a rotating block (2) is fixedly connected to the output end of the motor (4); the rotating block (2) is movably arranged in the stirring bin (101); an offset agitator (3) is fixedly connected to the top of the rotating block (2); a heating pipe (22) is fixedly mounted on the bottom wall of the stirring bin (101); a drainage pipe (5) is connected to the bottom of the stirring bin (101); a diaphragm pump (6) is connected to the other end of the drainage pipe (5); and the diaphragm pump (6) is located inside the discharge bin (102).

7. The intelligent culture medium configuration device and configuration machine according to claim 1, characterized in that: The medicine barrel (11) comprises a pH barrel and a culture medium raw material barrel. A pH meter (20) is fixedly installed on the top of the main body (1), and the detection end of the pH meter (20) is located inside the stirring chamber (101).

8. The intelligent culture medium configuration device and configuration machine according to claim 1, characterized in that: A control panel (25) is fixedly mounted on the side wall of the main body (1), and a GPS locator (19) is fixedly mounted on the top of the main body (1).

9. The intelligent culture medium configuration device and configuration machine according to claim 1, characterized in that: The medicine chamber (103) is divided into a normal temperature chamber (1031) and a cold storage chamber (1032). A heat insulation layer is fixedly connected to the inner wall of the cold storage chamber (1032), and a ceramic refrigeration plate (26) is fixedly installed inside the cold storage chamber (1032).