Intravascular embolism protection device

Abstract

The invention discloses an intravascular embolism protection device which comprises a conveying guide wire, a first filter and a second filter, and the first filter is located at the near end of the second filter; the first filter and the second filter are arranged at the far end of the conveying guide wire in a spaced mode so as to be used for intercepting different tissue substances in blood vessels and allowing blood to pass through, the first filter comprises a plurality of flexible brushes, the brushes are arranged on the peripheral wall of the conveying guide wire in a radial mode, and the first filter and the second filter are arranged on the periphery of the conveying guide wire. And the second filter comprises a net-shaped filter screen. Based on the intravascular embolism protection device, the far filtering channel and the near filtering channel which are used for filtering different tissues such as thrombus are arranged, the risk of thrombus escape can be effectively reduced, the thrombus can be blocked in a long area between the first filter and the second filter, and blood flow blocking caused by the fact that the thrombus is accumulated at one position is avoided.

Description

Technical Field

[0001] The present invention relates to the technical field of interventional medical equipment, and in particular to an intravascular embolism protection device. Background Art

[0002] During interventional cerebrovascular and lower limb arterial surgeries, surgical instruments may induce platelets in the blood to aggregate into various forms, including emboli, bacterial masses, and tiny tissue masses, or peel off atherosclerotic plaque fragments and particles from the arterial wall. These substances circulate in the blood and can invade the brain and other key arterial areas of the body, causing complications such as cerebral vascular embolism and below-the-knee vascular embolism.

[0003] In order to effectively prevent complications caused by embolic particles, distal protection devices are often used during surgery to capture plaque fragments flowing down the blood vessels and block the path of embolism. Currently, the distal protection devices on the market mainly use distal filter systems, such as the widely used Accunet protection device (Abbott), Angioguard protection device (Cordis) and Filterwire protection device (Boston Scientific).

[0004] However, existing products generally adopt a single-layer filter design. When the number of blood clots is too large or the volume is too large, the blood clots gather in the filter and easily cause blood vessel blockage. Summary of the invention

[0005] The purpose of the present invention is to provide an intravascular embolism protection device which can effectively prevent thrombus accumulation and blockage.

[0006] In order to achieve the above-mentioned object, the present invention provides an intravascular embolic protection device, which comprises a delivery guide wire, a first filter and a second filter, wherein the first filter is located at the proximal end of the second filter;

[0007] The first filter and the second filter are arranged at a distance from each other at the distal end of the delivery guide wire to intercept foreign tissue in the blood vessel and allow blood to pass through. The first filter includes a plurality of flexible brushes, which are radially arranged on the outer wall of the delivery guide wire. The second filter includes a mesh filter.

[0008] Preferably, it further comprises a delivery catheter, wherein the delivery guide wire is inserted into the delivery catheter, and the delivery catheter can slide along the delivery guide wire to collect the first filter and the second filter in the delivery catheter or release them into the blood vessel.

[0009] Preferably, when the delivery catheter releases the first filter and the second filter into a blood vessel, the open end of the filter net and the end of the brush facing away from the delivery guide wire abut against the inner wall of the blood vessel.

[0010] Preferably, the outer peripheral wall of the distal end of the delivery catheter is coated with a hydrophilic coating.

[0011] Preferably, the first filter further comprises a sleeve sleeved on the outer peripheral wall of the delivery guide wire, one end of the brush is fixed on the sleeve, the other end of the brush extends outward from the sleeve, and the sleeve is fixedly connected to the delivery guide wire.

[0012] Preferably, the second filter further comprises a plurality of support rods, wherein the support rods comprise a first fixed end and a movable end; the first fixed ends of a plurality of the support rods are centrally connected to the delivery guide wire, and the movable ends of a plurality of the support rods are radially spread out in a circumferential direction; the movable ends can be elastically retracted under the action of a restraining force;

[0013] The filter net is in a bag-like structure, including a second fixed end and an open end. The filter net is connected to the conveying guide wire via the second fixed end, and the open end is connected to the movable ends of several support rods; the first fixed end is located at the proximal end of the second fixed end.

[0014] Preferably, a developing member is disposed at one end and / or both ends of the first filter and the second filter, respectively.

[0015] Preferably, the second filter further comprises a first sliding ring, a second sliding ring, a first limiting ring and a second limiting ring which are sleeved on the delivery guide wire; the first sliding ring is located at the proximal end of the second sliding ring, the first limiting ring is located between the first sliding ring and the second sliding ring, and the second limiting ring is located at the distal end of the second sliding ring; the first sliding ring and the second sliding ring can slide relative to the delivery guide wire, the first limiting ring and the second limiting ring are fixed on the delivery guide wire, and the outer diameters of the first limiting ring and the second limiting ring are larger than the inner diameter of the second sliding ring;

[0016] The first fixed end is connected to the first sliding ring, and the second fixed end is connected to the second sliding ring.

[0017] Preferably, after the filter screen is unfolded, the diameter of the filter screen gradually decreases from the opening end to the second fixed end, so that the filter screen has a cone-shaped structure as a whole.

[0018] Preferably, the filter screen includes a first section and a second section, the second fixed end is located at the first section, and the open end is located at the second section. After the filter screen is unfolded, the diameter of the first section gradually increases from the second fixed end toward the second section, so that the first section has an overall conical structure, and the diameter of the second section along the axial direction is the same, so that the second section has an overall cylindrical structure.

[0019] Preferably, the filter screen is provided with a plurality of through holes, and the aperture of the through holes is between 70 and 130 microns.

[0020] Compared with the prior art, the intravascular embolism protection device disclosed in the above technical solution of the present invention is equipped with two filtering channels, one for filtering thrombus and other foreign tissues, which are a first filter based on a brush and a second filter based on a filter mesh, and the first filter is located at the proximal position of the second filter. Therefore, when the amount of thrombus is relatively large, part of the thrombus is blocked at the first filter, and part of the thrombus enters the second filter through the brush, thereby effectively reducing the risk of thrombus escape. Moreover, the thrombus can be blocked in the longer area between the first filter and the second filter to avoid the accumulation of thrombus in one place and causing blood flow obstruction. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 FIG. 1 is a plan view of the structure of an embolic protection device in one embodiment of the present invention in a use state.

[0022] Figure 2 for Figure 1 A plan view of the structure of the embolic protection device in a folded state.

[0023] Figure 3 for Figure 1 Three-dimensional structural diagram of the middle filter.

[0024] Figure 4 FIG. 4 is a plan view of the structure of an embolic protection device in another embodiment of the present invention in a use state.

[0025] Figure 5 for Figure 4 A plan view of the structure of the embolic protection device in a folded state.

[0026] Figure 6 for Figure 4 Three-dimensional structural diagram of the middle filter. DETAILED DESCRIPTION

[0027] In order to explain the technical content, structural features, achieved objectives and effects of the present invention in detail, the following is a detailed description in conjunction with the implementation methods and the accompanying drawings.

[0028] like Figure 1This embodiment discloses an intravascular embolism protection device for use in interventional cerebrovascular and lower limb artery surgery to prevent foreign tissues such as thrombus S that fall off from blood vessel G during surgery from circulating with the blood.

[0029] First, it should be noted that the term "distal end" in this embodiment and the following embodiments refers to the end close to the target position, and the "proximal end" refers to the end close to the surgical operator.

[0030] The protection device comprises a delivery guide wire 3 , a first filter 1 and a second filter 2 , wherein the first filter 1 is located at the proximal end of the second filter 2 .

[0031] The first filter 1 and the second filter 2 are arranged at a distance from each other at the distal end of the delivery guide wire 3 to intercept foreign tissue in the blood vessel G and allow blood to pass through. The first filter 1 includes a plurality of flexible brushes 10, which are radially arranged on the outer peripheral wall of the delivery guide wire 3. The second filter 2 includes a mesh filter 20.

[0032] When in use, the first filter 1 and the second filter 2 can be placed at the distal end of the target position, and foreign tissues such as thrombus S generated during the treatment process are first intercepted by the brush 10 of the first filter 1, and blood flows through the gaps between the brushes 10. When the amount of thrombus S is relatively large, some thrombus S can break through the interception of the brush 10 and reach the second filter 2 under the push of the blood flow, and then be intercepted by the filter net 20 of the second filter 2, while blood flows through the filter net 20. Therefore, the above-mentioned protective device can effectively reduce the risk of thrombus S escaping, and can block the thrombus S in the longer area between the first filter 1 and the second filter 2, so as to avoid the accumulation of thrombus S in one place and cause blood flow obstruction.

[0033] On the other hand, Figure 2 The protection device also includes a delivery catheter 4, a delivery guide wire 3 is inserted into the delivery catheter 4, and the delivery catheter 4 can slide along the delivery guide wire 3 to converge the first filter 1 and the second filter 2 into the delivery catheter 4 or release them into the blood vessel G.

[0034] In this embodiment, the first filter 1 and the second filter 2 can be pushed to the target position in the blood vessel G through the delivery catheter 4. During the pushing process, the first filter 1 and the second filter 2 are gathered in the delivery catheter 4 to prevent the first filter 1 and the second filter 2 from damaging the inner wall of the blood vessel G during the movement. After the first filter 1 and the second filter 2 are pushed to the target position, the delivery catheter 4 is withdrawn to release the first filter 1 and the second filter 2 into the blood vessel G in a protective state.

[0035] Further, when the delivery catheter 4 releases the first filter 1 and the second filter 2 into the blood vessel G, as shown in FIG. Figure 1The opening end 201 of the filter 20 and the end of the brush 10 facing away from the delivery guide wire 3 abut against the inner wall of the blood vessel G to prevent the thrombus S from escaping.

[0036] In addition, in order to allow the delivery catheter 4 to move smoothly in the blood vessel G and reduce damage to the inner wall of the blood vessel G during the movement of the delivery catheter 4, a hydrophilic coating (not shown) is coated on the outer peripheral wall of the distal end of the delivery catheter 4.

[0037] On the other hand, the first filter 1 further includes a sleeve 11 sleeved on the outer peripheral wall of the delivery guide wire 3, one end of the brush 10 is fixed on the sleeve 11, the other end of the brush 10 extends outward from the sleeve 11, and the sleeve 11 is fixedly connected to the delivery guide wire 3. Through the arrangement of the sleeve 11, the brush 10 can be conveniently fixed on the delivery guide wire 3. Specifically, a set of fastening rings 6 arranged on the delivery guide wire are respectively arranged at both ends of the sleeve 11 to fix the sleeve 11.

[0038] On the other hand, the second filter 2 further includes a plurality of support rods 21, and the support rods 21 include a first fixed end 210 and a movable end 211. The first fixed ends 210 of the plurality of support rods 21 are centrally connected to the delivery guide wire 3, and the movable ends 211 of the plurality of support rods 21 are radially spread out in the circumferential direction. The movable ends 211 can be elastically retracted under the restraining force of the delivery catheter 4.

[0039] The filter screen 20 is a bag-like structure, including a second fixed end 200 and an open end 201. The filter screen 20 is connected to the delivery guide wire 3 via the second fixed end 200, and the open end 201 is connected to the movable ends 211 of the plurality of support rods 21, so that the opening / closing of the open end 201 of the filter screen 20 is driven by the movable ends 211 of the plurality of support rods 21. The first fixed end 210 is located at the proximal end of the second fixed end 200.

[0040] Specifically, the support rod 21 in this embodiment is preferably made of a shape memory alloy, such as nickel-titanium alloy, cobalt-chromium alloy, etc., and the filter screen 20 can be made of a polymer material such as polycaprolactone, polypropylene, etc.

[0041] The brush 10 can be made of a polymer material such as polyethylene, polypropylene, etc. The brush 10 is bonded to the outer surface of the hollow sleeve 11 by glue.

[0042] like Figure 3 The filter screen 20 is provided with a plurality of through holes 202, and the aperture of the through holes 202 is between 70 and 130 microns, preferably between 80 and 110 microns.

[0043] On the other hand, a developing member 5 is provided at one end and / or both ends of the first filter 1 and the second filter 2 , respectively, so as to monitor the positions of the first filter 1 and the second filter 2 in the blood vessel G.

[0044] On the other hand, Figure 4 and Figure 5 The second filter 2 also includes a first sliding ring 70 , a second sliding ring 71 , a first limiting ring 80 and a second limiting ring 81 which are sleeved on the conveying guide wire 3 .

[0045] The first sliding ring 70 is located at the proximal end of the second sliding ring 71, the first limiting ring 80 is located between the first sliding ring 70 and the second sliding ring 71, and the second limiting ring 81 is located at the distal end of the second sliding ring 71. The first sliding ring 70 and the second sliding ring 71 can slide relative to the delivery guide wire 3, the first limiting ring 80 and the second limiting ring 81 are fixed on the delivery guide wire 3, and the outer diameters of the first limiting ring 80 and the second limiting ring are greater than the inner diameter of the second sliding ring 71.

[0046] The first fixed end 210 is connected to the first sliding ring 70 , and the second fixed end 200 is connected to the second sliding ring 71 .

[0047] In this embodiment, the first sliding ring 70 and the second sliding ring 71 are arranged so that the delivery guide wire 3 can slide relative to the second filter 2, and the maximum distance of relative sliding is the distance between the first limiting ring 80 and the second limiting ring 81. In this way, during the pushing process to the target position, the first limiting ring 80 abuts against the second sliding ring 71, and the delivery guide wire 3 pushes the second sliding ring 71 to move distally, that is, the second filter 2 is driven to move distally through the delivery guide wire 3. After the treatment is completed, when the delivery guide wire 3 is withdrawn, the second limiting ring 81 abuts against the second sliding ring 71, and the delivery guide wire 3 pulls the second sliding ring 71 to move proximally, that is, the second filter 2 is driven to move proximally through the delivery guide wire 3.

[0048] In addition, during the treatment process, the delivery guide wire 3 can be gently pushed to move in the distal direction, and the moving distance is less than the distance between the first limit ring 80 and the second sliding ring 71 at this time, so that the delivery guide wire 3 drives the brush 10 to move, and at the same time the delivery guide wire 3 slides in the first sliding ring 70 and the second sliding ring 71, and the second filter 2 abuts against the blood vessel wall, so that the second filter 2 remains stationary. Then, the movement of the brush 10 will clean up the thrombus S adhered to the inner wall of the blood vessel G, avoiding the residual thrombus S causing postoperative complications.

[0049] In addition, during the treatment, the delivery guide wire 3 can be gently rotated, so that the delivery guide wire 3 drives the brush 10 to rotate, and since the second sliding ring 71 is slidably connected to the delivery guide wire 3, the second filter 2 abuts against the blood vessel wall, and the second filter 2 remains stationary. Then, the movement of the brush 10 will clean up the thrombus S adhered to the inner wall of the blood vessel G, avoiding the residual thrombus S causing postoperative complications.

[0050] On the other hand, Figures 1 to 3After the filter screen 20 is unfolded, the diameter of the filter screen 20 gradually decreases from the opening end 201 to the second fixed end 200, so that the filter screen 20 has a cone-shaped structure as a whole.

[0051] On the other hand, Figures 4 to 6 The filter net 20 includes a first section D1 and a second section D2, the second fixed end 200 is located in the first section D1, and the open end 201 is located in the second section D2. After the filter net 20 is unfolded, the diameter of the first section D1 gradually increases from the second fixed end 200 to the second section D2, so that the first section D1 is a conical structure as a whole, and the diameter of the second section D2 along the axial direction is the same, so that the second section D2 is a cylindrical structure as a whole. In this embodiment, the filter net 20 is divided into two sections, which are conical and cylindrical structures respectively. Through the setting of the cylindrical second section D2, the contact area between the filter net 20 and the inner wall of the blood vessel G can be effectively increased, the wall adhesion of the filter net 20 is improved, and the escape rate of the thrombus S through the filter net 20 is reduced.

[0052] In summary, the present invention discloses an intravascular embolism protection device with a double-layer filtering effect. When performing interventional cerebrovascular and lower limb artery surgery, the operator pushes the entire delivery catheter 4 along the delivery guide wire 3 to a predetermined target position through the intervention sheath, then withdraws the delivery catheter 4, and releases the second filter 2 and the first filter 1 in turn. Then, the support rod 21 of the second filter 2 will be elastically unfolded, so that the open end 201 of the filter 20 is closely attached to the inner wall of the blood vessel G. The brush 10 is also automatically unfolded after losing the restraining force of the delivery catheter 4. The diameter of the brush 10 is equivalent to the inner diameter of the blood vessel G, ensuring that the brush 10 is in full contact with the thrombus S. When the number of thrombi S is too large or the volume is too large, a part of the thrombi S will be intercepted at the brush 10, and the other part will flow downstream through the gap of the brush 10 and be captured by the filter 20. During the operation, the delivery guide wire 3 can be gently pushed in the distal direction, so that the brush 10 moves in the blood vessel G to remove the thrombi S adhering to the inner wall of the blood vessel G.

[0053] After the operation is completed, the delivery catheter 4 is pushed to the target site, and the first filter 1 and the second filter 2 are retrieved in turn. During the process, the brush 10 is squeezed by the delivery catheter 4, and the thrombus S thereon may fall off, but it can still be captured again by the filter net 20 at the distal end.

[0054] The above disclosure is only the preferred embodiment of the present invention, which certainly cannot be used to limit the scope of rights of the present invention. Therefore, equivalent changes made according to the scope of the patent application of the present invention are still within the scope covered by the present invention.

Claims

1. An intravascular embolism protection device, characterized in that: It comprises a delivery guide wire, a first filter and a second filter, wherein the first filter is located at the proximal end of the second filter; The first filter and the second filter are arranged at a distance from each other at the distal end of the delivery guide wire to intercept foreign tissue in the blood vessel and allow blood to pass through. The first filter includes a plurality of flexible brushes, which are radially arranged on the outer wall of the delivery guide wire. The second filter includes a mesh filter.

2. The intravascular embolic protection device according to claim 1, characterized in that: It also includes a delivery catheter, in which the delivery guide wire is inserted, and the delivery catheter can slide along the delivery guide wire to collect the first filter and the second filter in the delivery catheter or release them into the blood vessel.

3. The intravascular embolic protection device according to claim 2, characterized in that: When the delivery catheter releases the first filter and the second filter into a blood vessel, the open end of the filter net and the end of the brush facing away from the delivery guide wire abut against the inner wall of the blood vessel.

4. The intravascular embolic protection device according to claim 1, characterized in that: The first filter also includes a sleeve sleeved on the outer peripheral wall of the delivery guide wire, one end of the brush is fixed on the sleeve, the other end of the brush extends outward from the sleeve, and the sleeve is fixedly connected to the delivery guide wire.

5. The intravascular embolic protection device according to claim 1, characterized in that: The second filter further comprises a plurality of support rods, wherein the support rods comprise a first fixed end and a movable end; the first fixed ends of a plurality of the support rods are centrally connected to the delivery guide wire, and the movable ends of a plurality of the support rods are radially spread out in a circumferential direction; the movable ends can be elastically retracted under the action of a restraining force; The filter net is in a bag-like structure, including a second fixed end and an open end. The filter net is connected to the conveying guide wire via the second fixed end, and the open end is connected to the movable ends of several support rods; the first fixed end is located at the proximal end of the second fixed end.

6. The intravascular embolic protection device according to claim 1, characterized in that: One end and / or both ends of the first filter and the second filter are respectively provided with developing parts.

7. The intravascular embolic protection device according to claim 5, characterized in that: The second filter also includes a first sliding ring, a second sliding ring, a first limiting ring and a second limiting ring which are sleeved on the delivery guide wire; the first sliding ring is located at the proximal end of the second sliding ring, the first limiting ring is located between the first sliding ring and the second sliding ring, and the second limiting ring is located at the distal end of the second sliding ring; the first sliding ring and the second sliding ring can slide relative to the delivery guide wire, the first limiting ring and the second limiting ring are fixed on the delivery guide wire, and the outer diameters of the first limiting ring and the second limiting ring are greater than the inner diameter of the second sliding ring; The first fixed end is connected to the first sliding ring, and the second fixed end is connected to the second sliding ring.

8. The intravascular embolic protection device according to claim 5, characterized in that: After the filter screen is unfolded, the diameter of the filter screen gradually decreases from the opening end to the second fixed end, so that the filter screen has a cone-shaped structure as a whole.

9. The intravascular embolic protection device according to claim 5, characterized in that: The filter net includes a first section and a second section, the second fixed end is located at the first section, and the open end is located at the second section. After the filter net is unfolded, the diameter of the first section gradually increases from the second fixed end toward the second section, so that the first section has a conical structure as a whole, and the diameter of the second section along the axial direction is the same, so that the second section has a cylindrical structure as a whole.

10. The intravascular embolic protection device according to claim 1, characterized in that: The filter screen is provided with a plurality of through holes, and the aperture of the through holes is between 70 and 130 microns.

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