An oil-control moisturizing composition, applications and cosmetics

Abstract

The application belongs to the field of new daily chemical materials, and particularly relates to an oil control and moisture retention composition, which comprises PEG-7 glyceryl cocoate 0.5-1.5%, PCA sodium 0.1-1%, bis-PEG-18 methyl ether dimethyl silane 1-3%, sage leaf oil 0.005-0.02%, and verbena oil 0.005-0.02%. The composition uses PEG-7 glyceryl cocoate, PCA sodium and bis-PEG-18 methyl ether dimethyl silane as main components, and uses sage leaf oil and verbena oil as oil components, so that the comprehensive oil control and moisture retention effect is achieved, the blood microcirculation and microecology of the scalp are improved, and the dandruff, oil control and moisture retention can be effectively achieved. Meanwhile, the application also provides the application of the composition.

Description

TECHNICAL FIELD

[0001] The present application belongs to the field of new materials for daily chemicals, and particularly relates to an oil-controlling and moisturizing composition, application and cosmetic. BACKGROUND

[0002] The generation of dandruff is related to various factors such as hormones, head skin cleaning degree, and head skin microecology; the secretion of head skin oil is an important head skin health index affecting dandruff, itching, and microecological balance;

[0003] The secretion of head skin oil is related to personal endocrine on one hand, and closely related to head skin blood circulation and whether the oil is cleaned in time on the other hand;

[0004] CN118141736A discloses a head skin oil-controlling and maintaining composition and a preparation method thereof, which reduces the secretion of sebum by reducing the activity of 5alpha-reductase and regulating the activity of cyclooxygenase COX-2 through a head skin maintenance material, balances the oil, and also establishes a cationic mutual composition through ion mutual exclusion technology, makes the hair roots fluffy under physical action conditions, avoids the hair covering the surface of the head skin pores due to gravity, causing the pores to be blocked and the oil to be accumulated.

[0005] CN118021662A discloses a head skin oil-controlling composition, a preparation method and application thereof. The head skin oil-controlling composition comprises, by weight: Norwegian spruce leaf extract 1-50 parts, Lotus corniculatus seed extract 0.01-10 parts, Sophora japonica bud extract 0.01-10 parts, Anemarrhena asphodeloides root extract 0.01-15 parts, Pueraria lobata extract 0.01-15 parts, and solvent 25-85 parts.

[0006] CN118021663A discloses a head skin soothing and oil-controlling essence. The essence takes water as a solvent, and the components thereof include, by mass percentage: 2-10% moisturizing agent, 1-4% Platycladus orientalis leaf extract, 0.8-2% arginine, 0.01-1% hydrolyzed royal jelly protein, 0.05-0.8% plant complex for reducing head skin sensitivity, 0.2-0.6% antibacterial agent, 0.01-0.6% Trifolium pratense flower extract, 0.005-0.6% beta-nicotinamide mononucleotide, 0.01-0.3% Schizosaccharomyces ferment filtrate, 0.1-0.2% thickening agent, 0.001-0.1% Phoenix dactylifera bark extract, and 0.001-0.06% polypeptide composition.

[0007] Most of the above solutions improve the oil secretion of the scalp from the aspects of plant extracts, plant oils, amino acids, fermentation products, etc.

[0008] In the long-term research of the present applicant, we believe that the health of the scalp is related to at least three aspects: 1. the secretion of healthy oil and the timely and proper removal of oil clogging pores; 2. the control of the blood microcirculation of the scalp to inhibit the intracellular lipid content; and 3. the improvement of the moisturizing performance of the scalp can improve the microecological balance of the scalp.

[0009] Therefore, the technical problem solved by the present application is: how to improve the oil control effect of the scalp and how to comprehensively control oil and remove dandruff. SUMMARY

[0010] Based on this, the first object of the present application is to provide an oil control and moisturizing composition, which adopts PEG-7 glyceryl cocoate, sodium PCA, and bis-PEG-18 methyl ether dimethyl silane as main components, and adopts salvia leaf oil and verbena oil as oil components, so as to achieve the effects of comprehensive oil control and moisturizing, improve the blood microcirculation and microecology of the scalp, and effectively remove dandruff, control oil, and moisturize.

[0011] The second object of the present application is to provide the application of the above-mentioned composition.

[0012] To achieve the first object of the present application, the following technical solutions are adopted:

[0013] An oil control and moisturizing composition comprises:

[0014] PEG-7 glyceryl cocoate 0.5-1.5%;

[0015] Sodium PCA 0.1-1%;

[0016] Bis-PEG-18 methyl ether dimethyl silane 1-3%;

[0017] Salvia leaf oil 0.005-0.02%;

[0018] Verbena oil 0.005-0.02%.

[0019] PEG-7 glyceryl cocoate is a non-ionic surfactant, which has the functions of decontamination and thickening, and is a hydrophilic emollient;

[0020] Sodium PCA (sodium pyrrolidone carboxylate) is a naturally occurring substance in the skin, which is an amino acid derivative, has strong hygroscopicity, can absorb water from the air, has stronger moisturizing power than glycerol, propylene glycol, and sorbitol, and has good moisturizing performance; at the same time, it has the function of strengthening the horny layer and enhancing the moisturizing ability of the skin itself;

[0021] Bis-PEG-18 methyl ether dimethyl silane is a commonly used surfactant, which has good moisturizing and nourishing properties.

[0022] In addition to the above three having good moisturizing and promoting skin to improve its own moisturizing properties, PEG-7 glyceryl cocoate has the characteristics of good compatibility with oil, and when combined with oil, it can significantly improve the spreading and penetration of oil on the scalp; Bis-PEG-18 methyl ether dimethyl silane, as a water-soluble wax, as a silane derivative, can improve the stability and dispersibility of plant oil in the system when used in shampoo.

[0023] Salvia leaf oil is a very widely used plant oil for the scalp, which can promote cell regeneration, especially for hair growth on the scalp. It can purify oily hair and dandruff, as it can inhibit excessive secretion of sebum. It is beneficial to inflamed and swollen skin.

[0024] Verbena oil can deeply condition the scalp and inhibit excessive secretion of sebum.

[0025] At the same time, salvia leaf oil and verbena oil have the function of improving blood microcirculation, which can further improve the secretion of sebum of scalp cells and maintain the secretion of sebum of scalp in a balanced state.

[0026] The efficacy of salvia leaf oil and verbena oil is based on the emulsion system that can deliver them smoothly to the scalp cells. Combined with the oil compatibility and penetration promoting function of PEG-7 glyceryl cocoate and the compatibility and stable dispersion function of bis-PEG-18 methyl ether dimethyl silane, it can exhibit more excellent functions of inhibiting sebum secretion and promoting cell regeneration when acting on scalp cells.

[0027] Through the mutual cooperation of the above components, the scalp health can be effectively improved, and excessive secretion of sebum and dandruff can be effectively inhibited.

[0028] In the above oil-controlling and moisturizing composition, it comprises:

[0029] PEG-7 glyceryl cocoate 0.8-1.2%;

[0030] PCA sodium 0.3-0.8%;

[0031] Bis-PEG-18 methyl ether dimethyl silane 1.5-2.5%;

[0032] Salvia leaf oil 0.008-0.015%;

[0033] Verbena oil 0.008-0.015%.

[0034] The oil-controlling and moisturizing composition described above also includes one or more of lemon peel oil, citronella oil, and ylang-ylang oil.

[0035] The above-mentioned oil-controlling and moisturizing composition also includes:

[0036] Lemon peel oil 0.005–0.02%;

[0037] Citronella oil 0.005–0.02%;

[0038] Ylang-ylang oil 0.005-0.02%.

[0039] The above-mentioned oil-controlling and moisturizing composition also includes:

[0040] Meadowfoam seed oil 0.005-0.02%.

[0041] It should be noted that while meadowfoam seed oil has some oil-controlling effect when used alone, it is far less effective than sage leaf oil or verbena oil. However, when used in combination with sage leaf oil or verbena oil, it effectively enhances the plant oils' ability to control sebum secretion. We believe this is because meadowfoam seed oil possesses unique skin-forming, moisturizing, and antioxidant properties, which can improve the spreadability, penetration, and antioxidant properties of sage leaf oil and verbena oil on the scalp, thereby enhancing the efficacy of the plant oils.

[0042] Furthermore, the present invention also discloses the use of the composition described above in the preparation of cosmetics.

[0043] In the above-mentioned uses, the cosmetic product is shampoo, conditioner, or hair cream.

[0044] Finally, the present invention also discloses a shampoo containing the composition described above.

[0045] The beneficial effects of this invention are as follows:

[0046] This invention uses PEG-7 glyceryl cocoate, sodium PCA, and bis-PEG-18 methyl ether dimethylsilane as the main components, and sage leaf oil and verbena oil as the oil components to achieve comprehensive oil control and moisturizing effects, improve scalp blood microcirculation and microecology, and effectively remove dandruff, control oil, and moisturize. Detailed Implementation

[0047] The technical solution of the present invention will be further illustrated below through specific embodiments. Those skilled in the art should understand that the embodiments described are merely illustrative of the present invention and should not be construed as limiting the invention in any way.

[0048] Unless otherwise indicated, the specific experimental procedures or conditions in the examples were carried out according to the conventional experimental procedures described in the literature. The reagents or instruments used were not specified by the manufacturer, and were all conventional reagents available on the market.

[0049] Supplier information and / or product information

[0050] PEG-7 glyceryl cocoate: provided by BASF (China) Co., Ltd.;

[0051] PCA sodium: provided by Kunshan Shuangyou Daily Chemical Co., Ltd.;

[0052] bis-PEG-18 methyl ether dimethyl silane: provided by Guangzhou Dongxiong Chemical Co., Ltd.;

[0053] sage leaf oil: provided by Guangzhou Lijing Fragrance & Flavor Co., Ltd.;

[0054] Verbena oil: provided by Guangzhou Lijing Fragrance & Flavor Co., Ltd.;

[0055] lemon peel oil: provided by Guangzhou Lijing Fragrance & Flavor Co., Ltd.;

[0056] Cymbopogon nardus oil: provided by Guangzhou Lijing Fragrance & Flavor Co., Ltd.;

[0057] Ylang ylang oil: provided by Guangzhou Lijing Fragrance & Flavor Co., Ltd.

[0058] Example

[0059] Preparation of an oil-controlling and moisturizing composition, which is prepared according to the following method:

[0060] Step 1: Add bis-PEG-18 methyl ether dimethyl silane raw material under stirring in water, heat to 80°C, completely disperse and dissolve, stirring speed 400-600 r / min;

[0061] Step 2: Add PEG-7 glyceryl cocoate raw material, stir until completely dissolved, keep warm for 30 minutes, stirring speed 100-400 r / min;

[0062] Step 3: Cool to 45 degrees, add PCA sodium, sage leaf oil, verbena oil, lemon peel oil, Cymbopogon nardus oil, Ylang ylang oil, and white pool flower seed oil (the above plant oils are added in step 3 if they are selected to be added in the formula; if not, the above components are ignored), stirring speed 100-400 r / min.

[0063] The specific formula is referred to Table 1;

[0064] Table 1 Formula Table

[0065]

[0066] Comparative Example

[0067] Preparation Method Reference Example

[0068] Formulation Reference Table 2

[0069] Table 2 Formulation Table

[0070]

[0071]

[0072] Test Example 1: Safety Test

[0073] 1. Formulation Safety Test

[0074] The compositions obtained in Examples 1-3, Example 7 were subjected to a chicken embryo chorioallantoic membrane test

[0075] Control and Test Sample Treatment

[0076] Sample: The compositions of Examples 1 to 3, Example 7.

[0077] Negative Control: Physiological saline.

[0078] Positive Control: 0.1 mol / L NaOH solution.

[0079] Test Operation Steps

[0080] Six chicken embryos were selected for each group in this test, and the chorioallantoic membrane was recorded using a photographing device. A polytetrafluoroethylene resin ring was placed on the chorioallantoic membrane of the chicken embryo and photographed. The sample to be tested was added to the polytetrafluoroethylene resin ring, the time of adding the sample was recorded, and a wet cling film was placed on the gas chamber. The chicken embryo was moved to a constant temperature and humidity incubator for cultivation, and the degree of change in each toxic effect was observed.

[0081] Calculation Results:

[0082] The test was conducted using the endpoint evaluation method, and the endpoint evaluation (ES) was calculated, with the results rounded to two decimal places; the score for each chicken embryo = the sum of the degree of bleeding, coagulation, and vascular resolution observed for each chicken embryo; ES = the average of the mathematical sum obtained for 6 chicken embryos. The average score for ES was calculated according to the following formula.

[0083]

[0084] Result Determination Criteria:

[0085] ES≤4, no irritation; 4< ES≤12, mild irritation; 12< ES< 16, moderate irritation; ES≥16, strong irritation / corrosion.

[0086] The experimental results are: all samples are non-irritating.

[0087] Test Example 2: Oil Control Test of the Composition

[0088] I. Test Method

[0089] (1) 5-alpha Reductase Inhibition Rate Test

[0090] Test Group Treatment

[0091] Sample Group: Diluted with buffer to a sample concentration of 20%;

[0092] Positive Control (Finasteride, purity ≥98%): Diluted with methanol to a positive control concentration of 0.1%;

[0093] Negative Control: Tris-HCl buffer.

[0094] Test Procedure

[0095] Set up sample group, positive control group, negative control group, and blank group, with 3 replicates for each group. Add different reagent solutions to each group, shake well, and perform HPLC analysis on each group to determine the testosterone content of each tube.

[0096] Calculation Formula

[0097]

[0098] Data Analysis

[0099] The statistical analysis software is SPSS. The comparison between the 5-alpha reductase inhibition rates of the test sample, positive control, and negative control uses independent sample t-test. The above statistical analysis is a two-tailed test with a significance level of a = 0.05. P ≥ 0.05 indicates no significant difference between the two groups; P < 0.05 indicates a significant difference between the two groups.

[0100] Result Determination Criteria

[0101] If the sample's 5-alpha reductase inhibition rate is higher than the negative control and has a significant difference (P < 0.05), it is considered that the test sample has certain oil control efficacy.

[0102] (2) Moisturizing Performance Test

[0103] Experimental Method

[0104] 2.1 Accurately weigh the sample;

[0105] 2.2 Select a control product with moisturizing efficacy;

[0106] 2.3 The moisture retention rate was determined in a constant temperature and humidity device with set temperature and humidity;

[0107] 2.4 The weighing determination was performed according to the set time;

[0108] 2.5 The moisture retention rate at each time point was calculated.

[0109] Correlation between experimental indexes and moisturizing efficacy

[0110] Moisture retention rate (%) = (1 - (m0-mn) / m0) x 100

[0111] m n - The total mass of the sample was continuously determined, in g;

[0112] m0- The total mass of the sample at the initial time, in g;

[0113] The control product used in this experiment was 5% glycerol, and the dosage form was consistent with the test sample. The added moisturizing agent glycerol is a common moisturizing agent and is widely used in cosmetics.

[0114] II. Test results

[0115] (1) The test results of 5-alpha reductase inhibition rate are shown in Table 4.

[0116] Table 4 5-alpha reductase inhibition results

[0117]

[0118]

[0119] Result analysis:

[0120] 1. As can be seen from Examples 1 to 3, the formula of the present application has certain oil control effect. In terms of dosage, the oil control effect of sage leaf oil is slightly better than that of verbena oil. As can be seen from Comparative Example 6, PEG-7 glyceryl cocoate, sodium PCA, and bis-PEG-18 methyl ether dimethyl silane contribute to oil control, but are not as good as sage leaf oil and verbena oil.

[0121] 2. As can be seen from Example 4, the addition of white pool flower seed oil can significantly promote the oil control effect. As can be seen from Comparative Example 6, the use of white pool flower seed oil alone does not significantly promote the oil control effect, indicating that the channel for white pool flower seed oil to play its effect may be that white pool flower seed oil has unique skin film-forming, moisturizing and antioxidant properties, thereby promoting the spreading, penetration and antioxidant properties of sage leaf oil and verbena oil on the scalp surface, and improving the efficacy of plant oils.

[0122] 3. It can be seen from Example 5, Example 6 and Example 7 that lemon peel oil, citronella oil and ylang ylang oil can improve the oil control effect to a certain extent, but the effect is not as good as that of sage leaf oil and verbena oil. It can be seen from Example 7 that the oil control effect can be significantly improved in the presence of white pool flower seed oil.

[0123] 4. It can be seen from Comparative Example 1 and Comparative Example 2 that sage leaf oil and verbena oil alone can have a certain oil control effect, and the effect of sage leaf oil alone is better. It can be seen from Comparative Example 3 and Comparative Example 4 that sage leaf oil and verbena oil alone can also have a good oil control effect when combined with white pool flower seed oil.

[0124] (2) The test results of the moisturizing performance are shown in Table 5.

[0125] The overall moisturizing rate test gap is not large, and only the moisturizing rate test results of the examples and Comparative Example 6, glycerol group are shown below.

[0126] Table 5 Moisturizing rate test results

[0127]

[0128]

[0129] Result analysis:

[0130] It can be seen from Table 5 that the moisturizing effect of each example and comparative example is similar to that of glycerol, which shows that the product of the present application can have a relatively good moisturizing effect.

[0131] Application example: a shampoo with the following formula shown in Table 6

[0132] Table 6 Formula table

[0133]

[0134]

Claims

1. An oil control moisturizing composition characterized in that, PEG-7 glyceryl cocoate 0.8-1.2%; PCA sodium 0.3-0.8%; bis-PEG-18 methyl ether dimethyl silane 1.5-2.5%; Clary sage leaf oil 0.008-0.015%; Verbena oil 0.008-0.015%; Lemon peel oil 0.005-0.02%; Citronella oil 0.005-0.02%; Ylang ylang oil 0.005-0.02%. Also comprising:

2. The oil control moisturizing composition of claim 1, wherein White pool seed oil 0.005-0.02%.

3. Use of a composition according to claim 1 or 2 for the manufacture of a cosmetic product. The cosmetic product is a shampoo, a hair conditioner or a hair shampooing paste.

4. Use according to claim 3, characterized in that, containing a composition according to claim 1 or 2.

5. A shampoo, characterized by, ​

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