Soothing and itching-relieving body-refreshing lotion and preparation method thereof

Abstract

The invention discloses a soothing and itching-relieving body-refreshing lotion. The lotion is prepared from the following substances in parts by weight: deionized water; modifying corn starch; calamine; diglycerol; glycerol; squalane; butanediol; zinc oxide; hydrogenating lecithin; phytosterol oleate; silica; the solvent is 1, 1, 2-hexanediol; glyceryl stearate citrate; phenoxyethanol; a Kava pepper root extract; arginine; an acrylic acid (ester) / C10-30 alkanol acrylate cross-linked polymer; xanthan gum; raspberry ketone; c11 to C13 isoparaffin is used as a catalyst; chlorphenesin; a dihydro oat acyl anthranilic acid; trimethylsiloxy silicate ester is used as a raw material; allantoin; tocopheryl acetate; a KasMongolian ginger root extract; disodium EDTA (Ethylene Diamine Tetraacetic Acid); and bisabolol; the invention relates to diphenylpolydimethylsiloxane. The product has the beneficial effects of removing peculiar smell and helping to absorb sweat and excessive grease, is mild and non-irritant, is easy to use and smear, has the effects of moisturizing and protecting skin, can be used for a long time, and can enhance the barrier of skin and enhance the protection function.

Description

Technical Field

[0001] The invention relates to the technical field of body lotions, in particular to a soothing and antipruritic body lotion and a preparation method thereof. Background Art

[0002] As is known to all, the use of talcum powder poses certain safety hazards to human health, and long-term use will have a profound impact on the lungs when inhaled. In order to solve these drawbacks and achieve the skin feeling effect brought by talcum powder after use, researchers have gradually developed a new dosage form - emulsion, such as CN115944560A, a talcum lotion and a preparation method thereof, which is prepared by using cassava starch, modified corn starch, an appropriate amount of silica, oil, emulsifier, thickener, and deionized water. The talcum lotion adopts a liquid formula, the amount of powder used is small, the talcum powder's talcum performance is brought into full play, and the amount of silica used is effectively controlled to ensure its safety;

[0003] CN113827488A An antibacterial body fragrance lotion and its preparation method, which is added with an antibacterial composition with a sustained release function, reduces sweat and body odor by long-term antibacterial on the body surface instead of blocking the sweat gland ducts, soothes the skin, and provides a dry and non-greasy skin feel;

[0004] CN101152137B A baby refreshing lotion and its preparation process can prevent excess powder from being inhaled into the baby's nasal cavity. The natural corn starch from plant sources is more adherent to the baby's tender skin, cools and nourishes the skin, and makes the baby's skin feel dry and refreshed.

[0005] The above products are mainly aimed at refreshing effects. Some products have added antibacterial, soothing and anti-prickly heat effects. In the patents that have been applied for, it is found that the use of plant extracts can achieve the function of antipruritic, but these effects cannot achieve lasting effects. Although the effects of calamine have been maturely used in the pharmaceutical industry, it cannot be attached to the skin for a long time, so its effect cannot be long-lasting. In addition, the skin is relatively dry after use, and the moisturizing and skin care effect is basically not achieved;

[0006] In view of the above situation, this study invented a body lotion containing innovative compounded plant extracts, which is mild, soothing and instantly relieves itching, meeting the multifunctional needs of consumers. It can not only be used by adults to remove odors, absorb sweat and excess oil, but is also suitable for infants and children. The product is mild and non-irritating. Summary of the invention

[0007] The technical solution of the present invention to achieve the above-mentioned purpose is a soothing and antipruritic body lotion, which is made of the following materials in parts by weight: 69.85 parts of deionized water; 6 parts of modified corn starch; 5 parts of calamine; 3 parts of diglycerol; 3 parts of glycerol; 2.5 parts of squalane; 2 parts of butylene glycol; 2 parts of zinc oxide; 1.5 parts of hydrogenated lecithin; 1 part of phytosteryl oleate; 1 part of silica; 0.5 parts of 1,2-hexanediol; 0.4 parts of glyceryl stearate citrate; 0.3 parts of phenoxyethanol; 0.25 parts of kava root extract; 0. 2 parts; acrylates / C10-30 alkyl acrylate crosspolymer 0.2 parts; xanthan gum 0.2 parts; raspberry ketone 0.2 parts; C11-13 isoparaffin 0.2 parts; chlorphenesin 0.15 parts; dihydrooatmoyl anthranilic acid 0.15 parts; trimethylsiloxysilicate 0.12 parts; allantoin 0.1 parts; tocopheryl acetate 0.1 parts; casamona ginger root extract 0.08 parts; disodium EDTA 0.05 parts; bisabolol 0.05 parts; diphenyl polydimethicone 0.05 parts.

[0008] A method for preparing a soothing and antipruritic body lotion comprises the following steps:

[0009] Step 1: Prepare raw materials;

[0010] Step 2: The raw materials are initially reacted to obtain item A and item B;

[0011] Step 3: React item A with item B;

[0012] Step 4: obtain raw materials.

[0013] To further supplement the technical solution, the raw material preparation includes the following steps:

[0014] Step 1) dispersing xanthan gum with an appropriate amount of butanediol, and then adding an appropriate amount of deionized water to dissolve it for standby use;

[0015] Step 2) Dispersing calamine, zinc oxide, modified corn starch, and silica with glycerol, diglycerol, and the remaining butylene glycol for standby use;

[0016] Step 3) dissolving dihydrooatmeal acyl anthranilic acid glycerol with arginine aqueous solution for standby use;

[0017] Step 4) Mix 1,2-hexanediol, phenoxyethanol and chlorphenesin and heat at 40°C-45°C until they are completely dissolved for later use.

[0018] To further supplement the technical solution, the preparation method of item A in step 2 is: add acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, allantoin, and disodium EDTA to deionized water, start heating and stirring, and heat to 80°C-85°C to obtain item A.

[0019] To further supplement the technical solution, the preparation method of item B in step 2 is: glyceryl stearate citrate, hydrogenated lecithin, phytosteryl oleate, squalane, diphenyl polydimethylsiloxane, trimethylsiloxysilicate, C11-13 isoparaffin and raspberry ketone are mixed and heated to melt evenly, and heated to 75°C-80°C to obtain item B.

[0020] To further supplement the technical solution, the specific preparation method of step three is: add item A to B, add spare a and homogenize for 1 minute, then add spare b and homogenize for 2-3 minutes, then add tocopherol acetate and bisabolol and continue stirring for 5 minutes.

[0021] To further supplement the technical solution, the specific preparation method of step 4 is: start cooling the substance obtained in step 3, add spare c when the temperature drops to 60°C, add spare d when the temperature drops to 40°C-45°C, continue stirring for 10min-15min, and check the pH, appearance, and viscosity.

[0022] As a further supplement to the technical solution, the time test indicators are the time of application, 30 minutes, 60 minutes, 120 minutes and 240 minutes.

[0023] Its beneficial effect lies in the effective compounding of calamine, zinc oxide, kava root extract, dihydrooatmoyl anthranilic acid and casammona ginger root extract, which can soothe the skin, achieve the effect of removing odor and instantly relieving itching and astringency, and can help control and reduce the occurrence of redness and inflammation of the skin; this innovative product is not only suitable for adults to use, remove odor, help absorb sweat and excess oil, but also very suitable for infants and children to use, can reduce the symptoms of baby red bottom, and has a long-lasting moisture absorption and drying effect. This product is mild and non-irritating, easy to use and apply, has moisturizing and skin care effects, can be used for a long time, can enhance the skin barrier and strengthen the protective function. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is a diagram of changes in skin microcirculation measured by the present invention. DETAILED DESCRIPTION

[0025] In order to make the technical solution more clear to those skilled in the art, Figure 1 The technical solution of the present invention is described in detail:

[0026] A soothing and antipruritic body lotion, the lotion is made of the following materials in parts by weight: 69.85 parts of deionized water; 6 parts of modified corn starch; 5 parts of calamine; 3 parts of diglycerol; 3 parts of glycerol; 2.5 parts of squalane; 2 parts of butylene glycol; 2 parts of zinc oxide; 1.5 parts of hydrogenated lecithin; 1 part of phytosteryl oleate; 1 part of silica; 0.5 parts of 1,2-hexanediol; 0.4 parts of glyceryl stearate citrate; 0.3 parts of phenoxyethanol; 0.25 parts of kava pepper root extract; 0.2 parts of arginine; acrylic acid (ester) ) / C10-30 alkyl acrylate crosspolymer 0.2 parts; xanthan gum 0.2 parts; raspberry ketone 0.2 parts; C11-13 isoparaffin 0.2 parts; chlorphenesin 0.15 parts; dihydrooatmoyl anthranilic acid 0.15 parts; trimethylsiloxysilicate 0.12 parts; allantoin 0.1 parts; tocopheryl acetate 0.1 parts; casamona ginger root extract 0.08 parts; disodium EDTA 0.05 parts; bisabolol 0.05 parts; diphenyl polydimethicone 0.05 parts.

[0027] A method for preparing a soothing and antipruritic body lotion comprises the following steps:

[0028] Step 1: Prepare raw materials;

[0029] Step 2: The raw materials are initially reacted to obtain item A and item B;

[0030] Step 3: React item A with item B;

[0031] Step 4: obtain raw materials.

[0032] To further supplement the technical solution, the raw material preparation includes the following steps:

[0033] Step 1) dispersing xanthan gum with an appropriate amount of butanediol, and then adding an appropriate amount of deionized water to dissolve it for standby use;

[0034] Step 2) Dispersing calamine, zinc oxide, modified corn starch, and silica with glycerol, diglycerol, and the remaining butylene glycol for standby use;

[0035] Step 3) dissolving dihydrooatmeal acyl anthranilic acid glycerol with arginine aqueous solution for standby use;

[0036] Step 4) Mix 1,2-hexanediol, phenoxyethanol and chlorphenesin and heat at 40°C-45°C until they are completely dissolved for later use.

[0037] Among them, the preparation method of item A in step 2 is: add acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, allantoin, and disodium EDTA into deionized water, start heating and stirring, and heat to 80°C-85°C to obtain item A.

[0038] Among them, the preparation method of item B in step 2 is: mix glyceryl stearate citrate, hydrogenated lecithin, phytosteryl oleate, squalane, diphenyl polydimethylsiloxane, trimethylsiloxysilicate, C11-13 isoparaffin and raspberry ketone, heat and melt evenly, heat to 75°C-80°C, and obtain item B.

[0039] The specific preparation method of step three is: add item A to B, add spare a and homogenize for 1 minute, then add spare b and homogenize for 2-3 minutes, then add tocopherol acetate and bisabolol and continue stirring for 5 minutes.

[0040] Among them, the specific preparation method of step four is: start cooling the substance prepared in step three, add spare c when the temperature drops to 60°C, add spare d when the temperature drops to 40°C-45°C, continue stirring for 10min-15min, and check the pH, appearance, and viscosity.

[0041] Among them, the time test indicators are the time of application, 30min, 60min, 120min, and 240min.

[0042] The performance of the present invention will be specifically described below according to experiments:

[0043] 1. Refreshing effect

[0044] 20 women aged 20-40 were asked to apply the formula lotion and placebo evenly on both sides of the face, and the overall effect was evaluated during application and 30min, 60min, 120min and 240min after application. The refreshing effect of this innovative product was evaluated mainly by inspecting the comfort, dryness, absence of redness and swelling, allergy, itching and skin care properties after application. Judging from the summary of the evaluation population, this product can meet the users' needs for refreshing body.

[0045] Time / skin assessment index Comfort Dryness No redness or swelling No allergy No itching Skin Care When applying 20 people 20 people 20 people 20 people 20 people 20 people 30min 20 people 20 people 20 people 20 people 20 people 20 people 60min 20 people 20 people 20 people 20 people 20 people 20 people 120min 19 people 20 people 18 people 19 people 19 people 20 people 240min 18 people 19 people 19 people 19 people 18 people 20 people

[0046] 2. Lasting effect

[0047] 30 men aged 25-45 were selected, and the formula lotion was evenly applied on the right half of the face, and another commercially available body lotion was evenly applied on the left half of the face. The smoothness and oil absorption effect of the face were evaluated and scored at the time of application, 30 minutes, 60 minutes, 120 minutes, and 240 minutes later. 0 points represented the most unsatisfactory and 10 points represented the most satisfied. The score of each indicator was recorded as the average score. The evaluation results are as follows:

[0048]

[0049] From the above scores, it can be seen that the formula lotion provides users with a longer-lasting smoothness effect.

[0050] 3. Soothing effect

[0051] According to CASTS / CEEC-RT-065-01 "Testing Program for Soothing, Repairing and Moisturizing Efficacy of Cosmetics", 32 healthy men and women aged 20-40 years old used the product for 4 consecutive weeks. Under the test conditions, according to the instrument test results, the hemoglobin index (EI) and red zone a of the 32 subjects after using the product * The values ​​were significantly improved (P<0.05), indicating that the test product has a soothing effect.

[0052] 4. Instant soothing and anti-itching effect

[0053] 10 women were screened and irradiated with infrared light for 30 minutes on their backs. The amount and area of ​​application on the back were kept consistent. The skin microcirculation was measured before and after infrared irradiation, and 15 minutes and 30 minutes after applying the formula lotion and placebo. The test results showed that the microcirculation of the back applied with the formula lotion normalized faster after IR irradiation, proving that the innovative product has an immediate soothing and antipruritic effect. Figure 1 As shown;

[0054] 5. Mild and non-irritating effect

[0055] Meet the inclusion criteria, effective number of 30 subjects; use the closed patch test method, place the test substance in the patch tester and apply it on the back of the subject, remove the test substance after 24 hours, observe the skin reaction 0.5, 24, and 48 hours after removal, and record the results according to the skin reaction grading standard in the "Safety Technical Specifications for Cosmetics" (2015 edition); the evaluation results are as follows:

[0056] Summary of cosmetic human skin patch test results

[0057]

[0058] The results showed that there were no cases of adverse skin reactions among the 30 subjects, thus proving that the product is mild (non-irritating).

[0059] The above technical solutions only reflect the preferred technical solutions of the technical solutions of the present invention. Some changes that may be made to certain parts thereof by technicians in this technical field all reflect the principles of the present invention and fall within the protection scope of the present invention.

Claims

1. A soothing and antipruritic body lotion, characterized in that: The emulsion is prepared from the following materials in parts by weight: 69.85 parts of deionized water; 6 parts of modified corn starch; 5 parts of calamine; 3 parts of diglycerol; 3 parts of glycerol; 2.5 parts of squalane; 2 parts of butylene glycol; 2 parts of zinc oxide; 1.5 parts of hydrogenated lecithin; 1 part of phytosteryl oleate; 1 part of silica; 0.5 parts of 1,2-hexanediol; 0.4 parts of glyceryl stearate citrate; 0.3 parts of phenoxyethanol; 0.25 parts of kava root extract; 0. 2 parts; acrylates / C10-30 alkyl acrylate crosspolymer 0.2 parts; xanthan gum 0.2 parts; raspberry ketone 0.2 parts; C11-13 isoparaffin 0.2 parts; chlorphenesin 0.15 parts; dihydrooatmoyl anthranilic acid 0.15 parts; trimethylsiloxysilicate 0.12 parts; allantoin 0.1 parts; tocopheryl acetate 0.1 parts; casammona ginger root extract 0.08 parts; disodium EDTA 0.05 parts; 0.05 parts of bisabolol and 0.05 parts of diphenyl dimethicone.

2. The method for preparing a soothing and antipruritic body lotion according to claim 1, characterized in that: The following steps are involved: Step 1: Prepare raw materials; Step 2: The raw materials are initially reacted to obtain item A and item B; Step 3: React item A with item B; Step 4: obtain raw materials.

3. The method for preparing a soothing and antipruritic body lotion according to claim 2, characterized in that: The raw material preparation comprises the following steps: Step 1) dispersing xanthan gum with an appropriate amount of butanediol, and then adding an appropriate amount of deionized water to dissolve it for standby use; Step 2) Dispersing calamine, zinc oxide, modified corn starch, and silica with glycerol, diglycerol, and the remaining butylene glycol for standby use; Step 3) dissolving dihydrooatmeal acyl anthranilic acid glycerol with arginine aqueous solution for standby use; Step 4) Mix 1,2-hexanediol, phenoxyethanol and chlorphenesin and heat at 40°C-45°C until they are completely dissolved for later use.

4. The method for preparing a soothing and antipruritic body lotion according to claim 3, characterized in that: The preparation method of item A in step 2 is: add acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, allantoin, and disodium EDTA into deionized water, start heating and stirring, and heat to 80° C.-85° C. to obtain item A.

5. The method for preparing a soothing and antipruritic body lotion according to claim 4, characterized in that: The preparation method of item B in the step 2 is: mix glyceryl stearate citrate, hydrogenated lecithin, phytosteryl oleate, squalane, diphenyl polydimethylsiloxane, trimethylsiloxysilicate, C11-13 isoparaffin and raspberry ketone, heat and melt evenly, and heat to 75°C-80°C to obtain item B.

6. The method for preparing a soothing and antipruritic body lotion according to claim 5, characterized in that: The specific preparation method of step three is: add item A to B, add spare a and homogenize for 1 minute, then add spare b and homogenize for 2-3 minutes, then add tocopherol acetate and bisabolol and continue stirring for 5 minutes.

7. The method for preparing a soothing and antipruritic body lotion according to claim 6, characterized in that: The specific preparation method of step 4 is: start cooling the material obtained in step 3, add spare c when the temperature drops to 60°C, add spare d when the temperature drops to 40°C-45°C, continue stirring for 10min-15min, and check pH, appearance, and viscosity.

8. A method for preparing a soothing and antipruritic body lotion according to any one of claims 2 to 7, characterized in that: The time test indicators are the time of application, 30min, 60min, 120min, and 240min.

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