Uric acid detection material Ce-UiO-66-X based on cerium-based UiO-66 as well as preparation method and application of uric acid detection material Ce-UiO-66-X
CN119334931APending Publication Date: 2025-01-21NORTHWESTERN POLYTECHNICAL UNIV
Patent Information
- Application Number
- CN202411498580.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-25
- Publication Date
- 2025-01-21
AI Technical Summary
Technical Problem
The existing uric acid detection methods have problems such as fragile natural enzyme activity, poor stability, environmental sensitivity and unstable organic color developer, resulting in poor detection accuracy and stability.
Method used
Develop a CE-UIO-66-X CE-UIO-66-X based on the cymbal-based UIO-66. It is prepared through the synthetic strategy of water phase. Quickly detect in one step.
Benefits of technology
The one-step colorimetric rapid detection of uric acid is achieved, and the detection time only takes 3 minutes. The material still has excellent reactivity under physiological pH conditions and has strong resistance to environmental interference.
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Figure CN119334931A_ABST
Abstract
The invention provides a uric acid detection material Ce-UiO-66-X based on cerium-based UiO-66 as well as a preparation method and application of the uric acid detection material Ce-UiO-66-X, and belongs to the technical field of uric acid detection. The uric acid detection material Ce-UiO-66-X is prepared on the basis of a cerium-based metal organic framework material, and Ce-UiO-66-X can convert uric acid into allantoin and generate hydrogen peroxide at the same time. In the presence of hydrogen peroxide, Ce-UiO-66-X can be changed from white to orange, rapid quantitative analysis of uric acid concentration is carried out, one-step colorimetric rapid detection analysis of uric acid can be realized without participation of natural urate oxidase, peroxidase and a color developing agent, and the detection time is only 3 minutes. Moreover, a green and efficient uric acid detection material Ce-UiO-66-X water phase synthesis strategy is developed by using a carboxylic acid regulator, a material basis is provided for constructing a novel enzyme-free uric acid rapid detection method, and the method is safe and environmentally friendly.
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Citation Information
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