Method and apparatus for cell fluid volume acquisition

Abstract

The application relates to the technical field of cell liquid, and provides a cell liquid volume acquisition method and device. The method comprises the following steps: a driving device is used to control a mixing plate to beat a mixing bag, so that the cell liquid in the mixing bag is subjected to a mixing operation; according to the volume change of the cell liquid in the mixing bag, the driving device is controlled to adjust a driving current, so that the cell liquid in the mixing bag is kept in a mixed state; and according to the current driving current of the driving device and a volume current function, the current volume of the cell liquid in the mixing bag is obtained. The cell liquid volume acquisition method and device provided in the application can avoid the adverse influence of the mixing operation on measurement, and improve the measurement accuracy of the cell liquid volume in the mixing operation.

Description

Technical Field

[0001] The present application relates to the field of cell fluid technology, and in particular to a method and device for obtaining cell fluid volume. Background Art

[0002] The mixed liquid to be packaged in the cell packaging equipment needs to be mixed and monitored in real time to ensure the consistency of the packaging concentration and the accuracy of the packaging. In this process, the volume of the cell liquid needs to be strictly monitored to control the progress of the cell liquid packaging.

[0003] There are various methods for monitoring cell sap volume, such as using load cells and pressure sensors. These methods measure the weight of the cell sap in a mixing bag and convert it to volume. However, these methods rely on direct contact with the mixing bag. During mixing operations, the mixing bag may be slapped or rotated, significantly affecting the accuracy of direct contact measurement and, consequently, the accuracy of the final calculated cell sap volume. Summary of the Invention

[0004] The embodiments of the present application provide a method and device for obtaining cell fluid volume, which is used to solve the technical problem that traditional cell fluid volume monitoring methods require direct contact weighing of the mixing bag during the mixing operation, affecting the weighing accuracy and further affecting the final cell fluid volume accuracy.

[0005] In a first aspect, an embodiment of the present application provides a method for obtaining a cell fluid volume, comprising:

[0006] Using a driving device to control the mixing plate to beat the mixing bag to mix the cell fluid in the mixing bag;

[0007] According to the volume change of the cell fluid in the mixing bag, controlling the driving device to adjust the driving current to control the cell fluid in the mixing bag to maintain a mixed state;

[0008] Obtaining a current volume of the cell fluid in the mixing bag according to a current driving current of the driving device and a volume current function;

[0009] The volume current function is obtained according to the historical volume of the cell fluid in the mixed state and the historical driving current of the driving device.

[0010] In one embodiment, the volume current function is obtained based on the following steps:

[0011] Obtain the volume of cell fluid at multiple moments within any time period to obtain multiple historical volumes;

[0012] Acquire the driving currents corresponding to the multiple moments to obtain multiple historical driving currents;

[0013] The plurality of historical volumes and the plurality of historical driving currents are fitted to obtain the volume current function.

[0014] In one embodiment, controlling the driving device to adjust the driving current according to the volume change of the cell fluid in the mixing bag includes:

[0015] According to the reduction in volume of the cell fluid in the mixing bag during packaging, the driving device is controlled to reduce the driving current.

[0016] In one embodiment, obtaining the current volume of the cell fluid in the mixing bag according to the current driving current of the driving device and the volume current function includes:

[0017] Inputting the current driving current into the volume current function to obtain the theoretical volume of the cell fluid in the mixing bag;

[0018] Acquire a historical driving current equal in magnitude to the current driving current to obtain a target historical driving current;

[0019] Acquiring a historical volume corresponding to the target historical driving current to obtain a target historical volume;

[0020] Predicting the current volume based on the target historical volume to obtain a predicted volume of the cell fluid in the mixing bag;

[0021] The current volume of the cell fluid in the mixing bag is obtained according to the theoretical volume and the predicted volume.

[0022] In one embodiment, obtaining the current volume of the cell fluid in the mixing bag according to the current driving current of the driving device and the volume current function includes:

[0023] Acquire the driving current at multiple moments within any time period; the multiple moments include the moment of acquiring the current driving current;

[0024] Calculate the average value and standard deviation of the driving current at all moments;

[0025] Performing error threshold screening on all the driving currents, and determining an average value of the screened driving currents as the target current driving current; the error threshold is calculated based on the average value and the standard deviation;

[0026] The target current driving current is input into the volume current function to obtain the current volume of the cell fluid in the mixing bag.

[0027] In one embodiment, obtaining the current volume of the cell fluid in the mixing bag according to the current driving current of the driving device and the volume current function includes:

[0028] Compare the changing trends of the current driving current and multiple historical driving currents on a time scale;

[0029] If the current driving current and the plurality of historical driving currents continue to decrease in chronological order, the current driving current is input into the volume current function to obtain the current volume of the cell fluid in the mixing bag.

[0030] In one embodiment, after obtaining the current volume of the cell solution in the mixing bag, the method further comprises:

[0031] comparing the change trends of the current volume of the cell fluid in the mixing bag and the multiple historical volumes on a time scale;

[0032] If the current volume and the plurality of historical volumes continue to decrease in chronological order, it is determined that the current volume passes the verification.

[0033] In a second aspect, an embodiment of the present application provides a cell fluid volume acquisition device, comprising:

[0034] A mixing control module is used to: use a driving device to control the mixing plate to beat the mixing bag to mix the cell fluid in the mixing bag;

[0035] a current adjustment module, configured to control the driving device to adjust the driving current according to the volume change of the cell fluid in the mixing bag, so as to control the cell fluid in the mixing bag to maintain a mixed state;

[0036] A volume acquisition module, configured to obtain a current volume of the cell fluid in the mixing bag according to a current driving current of the driving device and a volume current function;

[0037] The volume current function is obtained according to the historical volume of the cell fluid in the mixed state and the historical driving current of the driving device.

[0038] In a third aspect, an embodiment of the present application provides an electronic device comprising a processor and a memory storing a computer program, wherein when the processor executes the program, the steps of the cell fluid volume acquisition method described in the first aspect are implemented.

[0039] In a fourth aspect, an embodiment of the present application provides a non-transitory computer-readable storage medium, comprising a computer program, which, when executed by a processor, implements the steps of the cell fluid volume acquisition method described in the first aspect.

[0040] The cell fluid volume acquisition method and device provided in the present application utilize a driving device to control a mixing plate to beat a mixing bag to mix the cell fluid in the mixing bag. According to the volume change of the cell fluid in the mixing bag, the driving device is controlled to adjust the driving current to control the cell fluid in the mixing bag to maintain a mixed state. The current volume of the cell fluid in the mixing bag is obtained based on the current driving current of the driving device and the volume current function. As the volume of the cell fluid in the mixing bag changes, the required mixing and beating force also needs to change accordingly to ensure a better mixing effect. Therefore, it is necessary to adjust the driving current of the driving device to change the driving force of the driving device on the mixing plate, and then change the beating force of the mixing plate on the mixing bag. There is a one-to-one correspondence between the driving current and the volume of the cell fluid. Since the volume current function is obtained based on the historical volume of the cell fluid under the mixing state and the historical driving current of the driving device, it can characterize the one-to-one correspondence between the driving current and the volume of the cell fluid. The current volume of the cell fluid is mapped in the volume current function by the current driving current. No measuring equipment is used to perform direct contact measurement on the mixing bag during the mixing operation, which can avoid the adverse effects of the mixing operation on the measurement and improve the measurement accuracy of the cell fluid volume during the mixing operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0041] In order to more clearly illustrate the technical solutions in the present application or the prior art, a brief introduction will be given below to the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without any creative work.

[0042] Figure 1 This is one of the flow charts of the method for obtaining the cell fluid volume provided in the embodiments of the present application;

[0043] Figure 2 This is the second flow chart of the method for obtaining the cell fluid volume provided in the embodiment of the present application;

[0044] Figure 3 This is the third flow chart of the method for obtaining the cell fluid volume provided in the embodiment of the present application;

[0045] Figure 4 This is the fourth flow chart of the method for obtaining the cell fluid volume provided in the embodiment of the present application;

[0046] Figure 5 A schematic diagram of the structure of a cell fluid volume acquisition device provided in an embodiment of the present application;

[0047] Figure 6 It is a structural diagram of an electronic device provided in an embodiment of the present application. DETAILED DESCRIPTION

[0048] To make the objectives, technical solutions, and advantages of this application more clear, the technical solutions in this application will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of this application. Obviously, the described embodiments are only part of the embodiments of this application, not all of them. Based on the embodiments in this application, all other embodiments obtained by ordinary technicians in this field without making any creative efforts are within the scope of protection of this application.

[0049] Figure 1 This is one of the flow charts of the method for obtaining the volume of cell fluid provided in the embodiment of the present application. Figure 1 , the present application embodiment provides a method for obtaining the volume of cell fluid, which may include:

[0050] 101. Use a driving device to control the mixing plate to beat the mixing bag to mix the cell solution in the mixing bag;

[0051] 102. According to the volume change of the cell fluid in the mixing bag, the driving device is controlled to adjust the driving current to control the cell fluid in the mixing bag to maintain a mixed state;

[0052] 103. Obtaining the current volume of the cell solution in the mixing bag according to the current driving current of the driving device and the volume current function;

[0053] The volume current function is obtained based on the historical volume of the cell fluid measured in the mixed state and the historical driving current of the driving device.

[0054] In step 101, the driving device may be any device capable of driving the mixing plate, and is not limited here. In this embodiment, the driving device is a permanent magnet synchronous motor.

[0055] In step 102, the mixing state refers to the state of mixing the cell fluid in the mixing bag. When the volume of the cell fluid in the mixing bag increases, a greater beating force is applied to the mixing bag to achieve a better mixing effect. When the volume of the cell fluid in the mixing bag decreases, a smaller beating force is applied to the mixing bag to achieve a better mixing effect. Therefore, the beating force of the mixing bag needs to be adjusted according to the volume of the cell fluid in the mixing bag. On the one hand, it avoids insufficient force affecting the mixing effect, and on the other hand, it avoids excessive force causing waste.

[0056] The beating force of the mixing plate comes from the driving force of the drive device. For the drive motor, its driving force on the mixing plate is F = BILsinθ1, where B is the magnetic field strength, I is the driving current flowing through the drive motor, L is the length of the conductor (i.e., the magnet) inside the drive motor, and θ1 is the angle between the direction of the magnetic field strength B and the direction of the conductor. Because the magnetic field strength B inside the drive motor, the conductor length L, and the angle between the direction of the magnetic field strength B and the direction of the conductor are generally fixed values, the above formula shows that the driving force F is only related to the driving current and is positively correlated with the driving current.

[0057] Furthermore, the beating force of the mixing plate is only related to the driving current and is positively correlated with the driving current. Since the beating force of the mixing plate is positively correlated with the volume of cell fluid in the mixing bag, the volume of cell fluid in the mixing bag is positively correlated with the driving current.

[0058] Therefore, the driving device can be controlled to adjust the driving current according to the volume change of the cell fluid in the mixing bag, so as to control the cell fluid in the mixing bag to maintain a good mixing effect.

[0059] In addition, a current detector can be connected in series to the circuit passing through the driving device to obtain the driving current at each moment.

[0060] The cell fluid volume acquisition method provided in this embodiment uses a driving device to control a mixing plate to beat a mixing bag to mix the cell fluid in the mixing bag. According to the volume change of the cell fluid in the mixing bag, the driving device is controlled to adjust the driving current to control the cell fluid in the mixing bag to maintain a mixed state. The current volume of the cell fluid in the mixing bag is obtained based on the current driving current of the driving device and the volume current function. As the volume of the cell fluid in the mixing bag changes, the required mixing and beating force also needs to change accordingly to ensure a better mixing effect. Therefore, it is necessary to adjust the driving current of the driving device to change the driving force of the driving device on the mixing plate, and then change the beating force of the mixing plate on the mixing bag. There is a one-to-one correspondence between the driving current and the volume of the cell fluid. Since the volume current function is obtained based on the historical volume of the cell fluid under the mixing state and the historical driving current of the driving device, it can characterize the one-to-one correspondence between the driving current and the volume of the cell fluid. The current volume of the cell fluid is mapped in the volume current function by the current driving current. No measuring equipment is used to perform direct contact measurement on the mixing bag during the mixing operation, which can avoid the adverse effects of the mixing operation on the measurement and improve the measurement accuracy of the cell fluid volume during the mixing operation.

[0061] Figure 2 This is the second flow chart of the method for obtaining the volume of cell fluid provided in the embodiment of the present application. Figure 2 In one embodiment, the volume current function can be obtained based on the following steps:

[0062] 201. Obtain the volume of the cell fluid at multiple moments within any time period to obtain multiple historical volumes;

[0063] 202. Obtain driving currents corresponding to the multiple moments to obtain multiple historical driving currents;

[0064] 203. Fit the multiple historical volumes and the multiple historical driving currents to obtain a volume current function.

[0065] Before obtaining the current volume of the cell fluid, this embodiment obtains a volume current function based on the historical driving current and historical volume fitting, which can more accurately characterize the changing trend of the cell fluid volume with the driving current, thereby obtaining an accurate prediction value of the current volume of the cell fluid based on the current driving current and the volume current function.

[0066] In one embodiment, controlling the driving device to adjust the driving current according to the volume change of the cell solution in the mixing bag may include:

[0067] According to the reduction in volume of the cell solution in the mixing bag during packaging, the driving device is controlled to reduce the driving current.

[0068] When the cell fluid in the mixing bag is in the packaging state, the liquid inlet of the mixing bag is closed and only the liquid outlet is opened for liquid packaging. Therefore, the cell fluid in the mixing bag is in a state of continuous reduction. At this time, it is necessary to control the driving device to synchronously reduce the driving current in conjunction with the reduction in the volume of the cell fluid.

[0069] It should be noted that when the volume of the cell fluid in the mixing bag increases due to the inflow, the driving device can be controlled to increase the driving current in a similar manner.

[0070] This embodiment controls the driving device to reduce the driving current, so that the beating force of the mixing plate can be adaptively adjusted to match the volume of the cell fluid during the cell fluid packaging process.

[0071] Figure 3 This is the third flow chart of the method for obtaining the volume of cell fluid provided in the embodiment of the present application. Figure 3 In one embodiment, obtaining the current volume of the cell solution in the mixing bag according to the current driving current of the driving device and the volume current function may include:

[0072] 301. Input the current driving current into the volume current function to obtain the theoretical volume of the cell solution in the mixing bag;

[0073] 302. Obtain a historical driving current equal to the current driving current to obtain a target historical driving current;

[0074] 303. Acquire a historical volume corresponding to a target historical driving current to obtain a target historical volume;

[0075] 304. Predicting the current volume based on the target historical volume to obtain a predicted volume of the cell solution in the mixing bag;

[0076] 305. According to the theoretical volume and the predicted volume, the current volume of the cell solution in the mixing bag is obtained.

[0077] In step 302 , since the historical driving current having the same magnitude as the current driving current may not only be the driving current at a single historical moment, the obtained target historical driving current may also be a plurality of identical historical driving currents.

[0078] In step 303 , if the target historical driving current is a plurality of identical historical driving currents, the corresponding historical volumes are also a plurality of cell fluid volumes, and due to the existence of errors, the volumes of these cell fluids may also be different.

[0079] In step 304, the current volume is predicted based on the multiple historical volumes to obtain a predicted volume.

[0080] In step 305, the error between the theoretical volume and the predicted volume can be calculated. If the error is within an acceptable range, the theoretical volume is determined to be the current volume, or the average of the theoretical volume and the predicted volume is calculated and the average is used as the current volume, or the current volume is obtained by other methods, which are not limited here.

[0081] This embodiment performs theoretical calculation and predicted calculation on the current volume of the cell fluid, and then compares the theoretical volume and the predicted volume to verify each other, thereby obtaining a more accurate current volume of the cell fluid based on the two.

[0082] Figure 4 This is the fourth flow chart of the method for obtaining the volume of cell fluid provided in the embodiment of the present application. Figure 4 In one embodiment, obtaining the current volume of the cell solution in the mixing bag according to the current driving current of the driving device and the volume current function may include:

[0083] 401. Obtain driving currents at multiple moments within any time period;

[0084] The multiple moments include a moment of obtaining a current driving current;

[0085] 402. Calculate the average value and standard deviation of the driving current obtained at all moments;

[0086] 403. Perform error threshold screening on all driving currents, and determine the average value of the filtered driving currents as the target current driving current;

[0087] The error threshold is calculated based on the mean and standard deviation;

[0088] 404. Input the target current driving current into the volume current function to obtain the current volume of the cell solution in the mixing bag.

[0089] In step 401 , multiple driving currents including the current driving current may be acquired within a short period of time. For example, four driving currents may be acquired within 1 second. The last acquired current is the current driving current, and the others are historical driving currents.

[0090] In step 402, the average value of the four driving currents is calculated. and standard deviation θ2.

[0091] In step 403, if any one of the four driving currents exceeds the error threshold, the driving current is eliminated and the average value of the remaining driving currents is used as the final target current driving current; wherein the error threshold can be set according to actual conditions. In this embodiment, the error threshold can be The value of α may be determined according to the selected number of driving currents N. In this embodiment, the selected number of driving currents is 4, and the value of α may be N-1, that is, 3.

[0092] This embodiment corrects the current driving current by selecting a driving current close to the moment when the current driving current is obtained, and uses the average value of the driving current after removing random errors as the final current driving current, thereby greatly improving the accuracy of the current driving current, thereby simultaneously improving the accuracy of the current volume of the cell fluid obtained through the mapping relationship.

[0093] In one embodiment, obtaining the current volume of the cell solution in the mixing bag according to the current driving current of the driving device and the volume current function may include:

[0094] Compare the time-scale change trends of the current driving current and multiple historical driving currents. If the current driving current and multiple historical driving currents continue to decrease in chronological order, input the current driving current into the volume current function to obtain the current volume of the cell solution in the mixing bag.

[0095] Since the cell fluid in the mixing bag is in a sub-packaging state at this time, the volume of the cell fluid decreases with time. Since the driving current is positively correlated with the volume of the cell fluid, the driving current also decreases with time.

[0096] It should be noted that when the cell fluid in the mixing bag is in the liquid-inflowing state and the volume of the cell fluid increases with time, the current driving current and multiple historical driving currents continue to increase in chronological order. The current driving current is input into the volume current function to obtain the current volume of the cell fluid in the mixing bag.

[0097] This embodiment determines whether the current driving current conforms to the change in the cell fluid volume by detecting whether the driving current decreases over time during the packaging state, thereby determining the accuracy of the current driving current. The current driving current determined as accurate is input into the volume current function, and the corresponding current volume of the cell fluid is mapped to improve the accuracy of the current volume of the cell fluid.

[0098] In one embodiment, after obtaining the current volume of the cell solution in the mixing bag, the method may include:

[0099] The current volume of the cell solution in the mixing bag is compared with the change trends of the multiple historical volumes on a time scale. If the current volume and the multiple historical volumes continue to decrease in chronological order, it is determined that the current volume has passed the verification.

[0100] Since the cell fluid in the mixing bag is in a packaging state at this time, the volume of the cell fluid decreases over time.

[0101] It should be noted that, if the mixing bag is in a liquid filling state at this time, it can be determined that the current volume has passed the verification when the current volume and multiple historical volumes continue to increase in chronological order.

[0102] After obtaining the current volume of the cell fluid, this embodiment uses whether multiple cell fluid volumes decrease over time to determine whether the current volume is an actual change in the cell fluid volume, thereby verifying the obtained current volume, which can further improve the accuracy of the current volume of the cell fluid.

[0103] The cell fluid volume acquisition device provided in an embodiment of the present application is described below. The cell fluid volume acquisition device described below and the cell fluid volume acquisition method described above can be referenced to each other.

[0104] Figure 5 This is a schematic diagram of the structure of the cell fluid volume acquisition device provided in the embodiment of the present application. Figure 5 , an embodiment of the present application provides a cell fluid volume acquisition device, which may include:

[0105] The mixing control module 501 is used to: use a driving device to control the mixing plate to beat the mixing bag to mix the cell fluid in the mixing bag;

[0106] The current adjustment module 502 is used to control the driving device to adjust the driving current according to the volume change of the cell fluid in the mixing bag, so as to control the cell fluid in the mixing bag to maintain a mixed state;

[0107] The volume acquisition module 503 is configured to obtain the current volume of the cell solution in the mixing bag according to the current driving current of the driving device and the volume current function;

[0108] The volume current function is obtained according to the historical volume of the cell fluid in the mixed state and the historical driving current of the driving device.

[0109] The cell fluid volume acquisition device provided in this embodiment uses a driving device to control a mixing plate to beat a mixing bag to mix the cell fluid in the mixing bag. According to the volume change of the cell fluid in the mixing bag, the driving device is controlled to adjust the driving current to control the cell fluid in the mixing bag to maintain a mixed state. The current volume of the cell fluid in the mixing bag is obtained based on the current driving current of the driving device and the volume current function. As the volume of the cell fluid in the mixing bag changes, the required mixing and beating force also needs to change accordingly to ensure a better mixing effect. Therefore, it is necessary to adjust the driving current of the driving device to change the driving force of the driving device on the mixing plate, and then change the beating force of the mixing plate on the mixing bag. There is a one-to-one correspondence between the driving current and the volume of the cell fluid. Since the volume current function is obtained based on the historical volume of the cell fluid under the mixing state and the historical driving current of the driving device, it can characterize the one-to-one correspondence between the driving current and the volume of the cell fluid. The current volume of the cell fluid is mapped in the volume current function by the current driving current. No measuring equipment is used to perform direct contact measurement on the mixing bag during the mixing operation, which can avoid the adverse effects of the mixing operation on the measurement and improve the measurement accuracy of the cell fluid volume during the mixing operation.

[0110] In one embodiment, the volume current function is obtained based on the following steps:

[0111] Obtain the volume of cell fluid at multiple moments within any time period to obtain multiple historical volumes;

[0112] Acquire the driving currents corresponding to the multiple moments to obtain multiple historical driving currents;

[0113] The plurality of historical volumes and the plurality of historical driving currents are fitted to obtain the volume current function.

[0114] In one embodiment, the current adjustment module 502 is specifically configured to:

[0115] According to the reduction in volume of the cell fluid in the mixing bag during packaging, the driving device is controlled to reduce the driving current.

[0116] In one embodiment, the volume acquisition module 504 is specifically configured to:

[0117] Inputting the current driving current into the volume current function to obtain the theoretical volume of the cell fluid in the mixing bag;

[0118] Acquire a historical driving current equal in magnitude to the current driving current to obtain a target historical driving current;

[0119] Acquiring a historical volume corresponding to the target historical driving current to obtain a target historical volume;

[0120] Predicting the current volume based on the target historical volume to obtain a predicted volume of the cell fluid in the mixing bag;

[0121] The current volume of the cell fluid in the mixing bag is obtained according to the theoretical volume and the predicted volume.

[0122] In one embodiment, the volume acquisition module 504 is specifically configured to:

[0123] Acquire the driving current at multiple moments within any time period; the multiple moments include the moment of acquiring the current driving current;

[0124] Calculate the average value and standard deviation of the driving current at all moments;

[0125] Performing error threshold screening on all the driving currents, and determining an average value of the screened driving currents as the target current driving current; the error threshold is calculated based on the average value and the standard deviation;

[0126] The target current driving current is input into the volume current function to obtain the current volume of the cell fluid in the mixing bag.

[0127] In one embodiment, the volume acquisition module 504 is specifically configured to:

[0128] Compare the changing trends of the current driving current and multiple historical driving currents on a time scale;

[0129] If the current driving current and the plurality of historical driving currents continue to decrease in chronological order, the current driving current is input into the volume current function to obtain the current volume of the cell fluid in the mixing bag.

[0130] In one embodiment, a volume verification module (not shown) is further included, configured to:

[0131] comparing the change trends of the current volume of the cell fluid in the mixing bag and the multiple historical volumes on a time scale;

[0132] If the current volume and the plurality of historical volumes continue to decrease in chronological order, it is determined that the current volume passes the verification.

[0133] Figure 6 An example of a physical structure diagram of an electronic device is shown below. Figure 6As shown, the electronic device may include: a processor 610, a communication interface 620, a memory 630, and a communication bus 640, wherein the processor 610, the communication interface 620, and the memory 630 communicate with each other via the communication bus 640. The processor 610 may call a computer program in the memory 630 to execute the steps of the cell fluid volume acquisition method, for example, including:

[0134] Using a driving device to control the mixing plate to beat the mixing bag to mix the cell fluid in the mixing bag;

[0135] According to the volume change of the cell fluid in the mixing bag, controlling the driving device to adjust the driving current to control the cell fluid in the mixing bag to maintain a mixed state;

[0136] Obtaining a current volume of the cell fluid in the mixing bag according to a current driving current of the driving device and a volume current function;

[0137] The volume current function is obtained according to the historical volume of the cell fluid in the mixed state and the historical driving current of the driving device.

[0138] In addition, the logic instructions in the above-mentioned memory 630 can be implemented in the form of a software functional unit and can be stored in a computer-readable storage medium when sold or used as an independent product. Based on this understanding, the technical solution of the present application, or the part that contributes to the prior art or the part of the technical solution, can be embodied in the form of a software product, which is stored in a storage medium and includes several instructions for enabling a computer device (which can be a personal computer, a server, or a network device, etc.) to execute all or part of the steps of the method described in each embodiment of the present application. The aforementioned storage medium includes: various media that can store program codes, such as a USB flash drive, a mobile hard disk, a read-only memory (ROM), a random access memory (RAM), a magnetic disk or an optical disk.

[0139] On the other hand, embodiments of the present application further provide a computer program product, comprising a computer program. The computer program may be stored on a non-transitory computer-readable storage medium. When the computer program is executed by a processor, the computer can perform the steps of the cell fluid volume acquisition method provided in the above embodiments, for example, including:

[0140] Using a driving device to control the mixing plate to beat the mixing bag to mix the cell fluid in the mixing bag;

[0141] According to the volume change of the cell fluid in the mixing bag, controlling the driving device to adjust the driving current to control the cell fluid in the mixing bag to maintain a mixed state;

[0142] Obtaining a current volume of the cell fluid in the mixing bag according to a current driving current of the driving device and a volume current function;

[0143] The volume current function is obtained according to the historical volume of the cell fluid in the mixed state and the historical driving current of the driving device.

[0144] On the other hand, an embodiment of the present application further provides a processor-readable storage medium, wherein the processor-readable storage medium stores a computer program, wherein the computer program is configured to cause a processor to execute the steps of the methods provided in the above embodiments, for example, including:

[0145] Using a driving device to control the mixing plate to beat the mixing bag to mix the cell fluid in the mixing bag;

[0146] According to the volume change of the cell fluid in the mixing bag, controlling the driving device to adjust the driving current to control the cell fluid in the mixing bag to maintain a mixed state;

[0147] Obtaining a current volume of the cell fluid in the mixing bag according to a current driving current of the driving device and a volume current function;

[0148] The volume current function is obtained according to the historical volume of the cell fluid in the mixed state and the historical driving current of the driving device.

[0149] The processor-readable storage medium can be any available medium or data storage device that can be accessed by the processor, including but not limited to magnetic storage (such as floppy disks, hard disks, magnetic tapes, magneto-optical disks (MO)), optical storage (such as CDs, DVDs, BDs, HVDs, etc.), and semiconductor storage (such as ROMs, EPROMs, EEPROMs, non-volatile memories (NANDFLASH), solid-state drives (SSDs)), etc.

[0150] The device embodiments described above are merely illustrative. The units described as separate components may or may not be physically separate, and the components shown as units may or may not be physical units, i.e., they may be located in one location or distributed across multiple network units. Some or all of the modules may be selected based on actual needs to achieve the objectives of the present embodiment. Persons of ordinary skill in the art will be able to understand and implement the present invention without inventive effort.

[0151] Through the description of the above embodiments, those skilled in the art can clearly understand that each embodiment can be implemented by means of software plus a necessary general hardware platform, or of course, by hardware. Based on this understanding, the essence of the above technical solution or the part that contributes to the existing technology can be embodied in the form of a software product. The computer software product can be stored in a computer-readable storage medium, such as ROM / RAM, a magnetic disk, an optical disk, etc., and includes a number of instructions for enabling a computer device (which can be a personal computer, a server, or a network device, etc.) to execute the methods described in each embodiment or certain parts of the embodiments.

[0152] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them. Although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present application.

Claims

1. A method for obtaining cell fluid volume, characterized in that: include: Using a driving device to control the mixing plate to beat the mixing bag to mix the cell fluid in the mixing bag; According to the volume change of the cell fluid in the mixing bag, controlling the driving device to adjust the driving current to control the cell fluid in the mixing bag to maintain a mixed state; Obtaining the current volume of the cell solution in the mixing bag according to the current driving current of the driving device and the volume current function, including: Acquire the driving current at multiple moments within any time period; the multiple moments include the moment of acquiring the current driving current; Calculate the average value and standard deviation of the driving current at all moments; Performing error threshold screening on all the driving currents, and determining an average value of the screened driving currents as the target current driving current; the error threshold is calculated based on the average value and the standard deviation; Inputting the target current driving current into the volume current function to obtain the current volume of the cell fluid in the mixing bag; The volume current function is obtained according to the historical volume of the cell fluid in the mixed state and the historical driving current of the driving device, and includes: Obtain the volume of cell fluid at multiple moments within any time period to obtain multiple historical volumes; Acquire the driving currents corresponding to the multiple moments to obtain multiple historical driving currents; The plurality of historical volumes and the plurality of historical driving currents are fitted to obtain the volume current function.

2. The method for obtaining the cell fluid volume according to claim 1, wherein: The step of controlling the driving device to adjust the driving current according to the volume change of the cell fluid in the mixing bag comprises: According to the reduction in volume of the cell fluid in the mixing bag during packaging, the driving device is controlled to reduce the driving current.

3. The method for obtaining the cell fluid volume according to claim 1, wherein: Obtaining the current volume of the cell fluid in the mixing bag according to the current driving current of the driving device and the volume current function includes: Inputting the current driving current into the volume current function to obtain the theoretical volume of the cell fluid in the mixing bag; Acquire a historical driving current equal in magnitude to the current driving current to obtain a target historical driving current; Acquiring a historical volume corresponding to the target historical driving current to obtain a target historical volume; Predicting the current volume based on the target historical volume to obtain a predicted volume of the cell fluid in the mixing bag; The current volume of the cell fluid in the mixing bag is obtained according to the theoretical volume and the predicted volume.

4. The method for obtaining the cell fluid volume according to claim 2, wherein: Obtaining the current volume of the cell fluid in the mixing bag according to the current driving current of the driving device and the volume current function includes: Compare the changing trends of the current driving current and multiple historical driving currents on a time scale; If the current driving current and the plurality of historical driving currents continue to decrease in chronological order, the current driving current is input into the volume current function to obtain the current volume of the cell fluid in the mixing bag.

5. The method for obtaining the cell fluid volume according to claim 4, wherein: After obtaining the current volume of the cell solution in the mixing bag, the method further comprises: comparing the change trends of the current volume of the cell fluid in the mixing bag and the multiple historical volumes on a time scale; If the current volume and the plurality of historical volumes continue to decrease in chronological order, it is determined that the current volume passes the verification.

6. A cell fluid volume acquisition device, characterized in that: The method for obtaining the volume of cell fluid according to claim 1 comprises: A mixing control module is used to: use a driving device to control the mixing plate to beat the mixing bag to mix the cell fluid in the mixing bag; a current adjustment module, configured to control the driving device to adjust the driving current according to the volume change of the cell fluid in the mixing bag, so as to control the cell fluid in the mixing bag to maintain a mixed state; A volume acquisition module, configured to obtain a current volume of the cell fluid in the mixing bag according to a current driving current of the driving device and a volume current function; The volume current function is obtained according to the historical volume of the cell fluid in the mixed state and the historical driving current of the driving device.

7. An electronic device comprising a processor and a memory storing a computer program, characterized in that: When the processor executes the computer program, the steps of the method for obtaining the cell fluid volume according to any one of claims 1 to 5 are implemented.

8. A non-transitory computer-readable storage medium having a computer program stored thereon, characterized in that: When the computer program is executed by a processor, the steps of the method for obtaining the cell fluid volume according to any one of claims 1 to 5 are implemented.

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