Bone marrow blood collecting and filtering equipment

Abstract

The invention provides bone marrow blood collecting and filtering equipment, and belongs to the field of bone marrow blood collection, the bone marrow blood collecting and filtering equipment comprises a fixing frame component, the fixing frame component is detachably connected with a main pipeline and an injection head, the main pipeline is further detachably connected with a medicine storage bottle through an injection pipeline, the medicine storage bottle is filled with heparin liquid, and the injection head is detachably connected with the main pipeline. A fixed pressure component is installed on the injection pipeline, a collecting component is detachably installed at the end, away from the fixing frame component, of the main pipeline, and the collecting component can automatically collect spinal cord blood. The heparin liquid in the medicine storage bottle can be automatically sucked, the bone marrow blood is sucked and flows through the multi-stage filter and can be filtered to obtain relatively pure hematopoietic stem cells, so that the device can realize highly automatic collection of the bone marrow blood without repeatedly replacing an injector and a tedious artificial bone marrow blood filtering process; and the dependence on medical staff is reduced.

Description

Technical Field

[0001] The present invention relates to the field of bone marrow blood collection, and more particularly to a bone marrow blood collection and filtering device. Background Art

[0002] Bone marrow blood refers to a blood sample extracted from the bone marrow cavity. It contains a large number of hematopoietic stem cells, most of which are immature and have not yet fully developed functions.

[0003] During the bone marrow collection process, small marrow particles, blood clots, or other impurities may be present. If these impurities are not removed, they may affect subsequent processing and application. Filtration can effectively remove these impurities and ensure the purity and quality of the bone marrow blood.

[0004] Before bone marrow blood collection, nurses need to prepare a large number of syringes filled with heparin solution, depending on the amount of marrow to be collected. After preparation, the physician first administers local anesthesia at the site to be punctured. The physician then inserts the bone marrow collection needle into the bone marrow cavity (typically the posterior superior iliac spine). The heparinized syringe is then connected to the needle, and the bone marrow collection is then manually aspirated. The amount collected varies depending on the patient's weight, and each aspiration requires a new syringe, placing a high level of dependency on medical personnel. Furthermore, because the aspirated bone marrow blood contains impurities such as clots, white blood cells, fat droplets, and bone particles, the collected blood must undergo a secondary filtration procedure to obtain relatively pure hematopoietic stem cells. Currently, this clinical procedure is cumbersome, and the bone marrow filtration process carries the risk of exposure and contamination.

[0005] In view of this, and in response to the above-mentioned shortcomings, the present invention provides a bone marrow blood collection and filtering device. Summary of the Invention

[0006] In response to the problems existing in the prior art, the purpose of the present invention is to provide a bone marrow blood collection and filtration device that can achieve highly automated bone marrow blood collection, eliminating the need for repeated replacement of syringes and cumbersome manual bone marrow blood filtration processes, thereby reducing dependence on medical staff.

[0007] To solve the above problems, the present invention adopts the following technical solutions.

[0008] A bone marrow blood collection and filtering device comprises a fixing frame component, to which a main pipeline and an injection head are detachably connected, the main pipeline is further detachably connected to a medicine storage bottle via an injection pipeline, the medicine storage bottle being filled with heparin solution, a constant pressure component being mounted on the injection pipeline, a collection component being detachably mounted on an end of the main pipeline remote from the fixing frame component, the collection component being capable of automatically collecting spinal cord blood, a plurality of evenly distributed first filters being mounted in series on the main pipeline, each of the first filters being connected in parallel to a second filter, a constant pressure component being connected between an input end of the second filter and the main pipeline, the constant pressure component being used to limit the pressure at various locations within the main pipeline;

[0009] The collection component includes a bellows, a cover body is detachably installed on the top of the bellows, a base is integrally formed at the bottom of the bellows, a plurality of center rods distributed in a ring are fixedly installed on the upper surface of the base, a second spring is sleeved on the outside of the center rods, a plurality of lifting cylinders corresponding to the center rods are fixedly installed on the cover body, and a blood storage bag is provided inside the bellows.

[0010] Optionally, the external sliding sleeve of the center rod is provided with a sliding plate, the top end of the second spring is fixedly installed with a limit plate, the limit plate is located inside the lifting cylinder, a plurality of evenly distributed through grooves are opened on the sliding plate, and a plurality of groups of evenly distributed blocks are fixedly installed inside the lifting cylinder, and the number of blocks in each group corresponds to the number of through grooves.

[0011] Optionally, a movable bracket is provided above the cover body, and multiple lifting cylinders are rotatably installed on the movable bracket. Multiple evenly distributed first screws are also rotatably installed on the movable bracket, and multiple threaded sleeves corresponding to the first screws are fixedly installed on the cover body. The first screw is clamped inside the threaded sleeve through a thread.

[0012] Optionally, two mutually symmetrical support members are installed on the upper surface of the base, and a third screw is rotatably installed between the support member and the base, and the bottom end of the third screw is fixedly installed with a first gear, and the middle part of the upper surface of the base is rotatably installed with a second gear, and the second gear is connected to the two first gears through a rack belt, and a movable plate is provided on both sides of the second gear, and multiple center rods are slidably clamped on the corresponding movable plates, and the second spring is clamped by the sliding plate and the movable plate, and a turning handle is rotatably installed in the middle part of the lower surface of the base, and the turning handle is fixedly connected to the second gear.

[0013] Optionally, the constant pressure component includes an upper shell and a lower shell, the upper shell and the lower shell are combined to form a closed chamber, the lower shell is sleeved on the end of the upper shell by threaded fitting, an input pipe is fixedly installed in the middle of the upper shell, and an output pipe is fixedly installed in the middle of the lower shell, the input pipe and the output pipe are both connected to the closed chamber, the input pipe extends into the interior of the closed chamber, a first spring is fixedly installed inside the lower shell, a sealing ball is fixedly installed on the first spring, and the sealing ball is pushed against the input pipe by the first spring.

[0014] Optionally, the fixed frame component includes a seat plate, guide rails are fixedly installed on the upper surfaces of both ends of the seat plate, a slider is provided on the internal sliding card of the guide rail, a rotating rod is rotatably installed on the upper surface of the slider, an arc-shaped support frame is provided above the fixed frame component, a second screw is fixedly installed on both ends of the arc-shaped support frame, the second screw is clamped inside the rotating rod through threaded engagement, and a locking piece for fixing the position is installed on the slider.

[0015] Optionally, the lifting cylinder is made of a transparent material, and scale lines are engraved on the inner wall of each lifting cylinder.

[0016] Optionally, a connection interface is fixedly installed in the middle of the cover body, the lower end of the connection interface extends into the interior of the corrugated cylinder, and the blood storage bag is detachably connected to the lower end of the connection interface.

[0017] Optionally, a plurality of sealing rings corresponding to the lifting cylinder are fixedly mounted on the upper surface of the cover body, and the sealing rings are sealingly movably sleeved on the outer surface of the corresponding lifting cylinder.

[0018] Optionally, a rotating block is rotatably installed in the middle of the arc-shaped support frame, and a first pipe, a second pipe, and a third pipe are fixedly installed on the rotating block. The second pipe, the first pipe, and the third pipe are connected in sequence. The medicine storage bottle is detachably connected to the third pipe through the injection pipe, the main pipe is detachably connected to the first pipe, and the injection head is detachably connected to the second pipe.

[0019] Compared with the prior art, the technical solution provided by the present invention has at least the following beneficial effects:

[0020] Through the coordination between various components, the constant pressure component connected to the medicine storage bottle opens during the absorption process, so that the heparin liquid inside the medicine storage bottle can be automatically absorbed. The bone marrow blood is absorbed and flows through a multi-stage filter to be filtered to obtain relatively pure hematopoietic stem cells. Therefore, this device can realize highly automated bone marrow blood collection, without the need for repeated replacement of syringes and cumbersome manual bone marrow blood filtration processes, reducing dependence on medical staff.

[0021] By setting up a movable plate and a lifting cylinder, the device is equipped with a multi-stage pressure regulating mechanism, which can adjust the pressing amplitude of the entire corrugated barrel according to the strength of the elastic deformation of the corrugated barrel and the lifting cylinder, and then adjust the negative pressure suction generated by the device, and then adjust the force of the device's absorption to prevent excessive negative pressure from causing discomfort to the patient.

[0022] By setting up the collection component, the cover will rebound to its original position under the action of the second spring, and then absorb an equal amount of bone marrow blood through the main pipeline. The absorption amount can be easily adjusted to achieve quantitative absorption, and there is no need to repeatedly change the container for collection.

[0023] By connecting multiple second filters in parallel, the bone marrow blood flow pipe can be automatically and quickly replaced when blockage occurs, preventing abnormal bone marrow blood collection caused by pipe blockage. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The accompanying drawings, which are incorporated herein and constitute a part of the specification, illustrate embodiments of the invention and, together with the description, further serve to explain the principles of the invention and to enable one skilled in the art to make and use the invention.

[0025] Figure 1 It is a schematic structural diagram of the present invention as a whole;

[0026] Figure 2 It is a structural diagram of the collection component in the present invention;

[0027] Figure 3 It is a schematic diagram of the cross-section structure of the collection component in the present invention;

[0028] Figure 4 For the present invention Figure 3 Enlarged view of point A in the middle;

[0029] Figure 5 This is a schematic structural diagram of the first gear and the second gear in the present invention;

[0030] Figure 6 Schematic diagram of the connection structure between the first screw and the threaded sleeve in the present invention;

[0031] Figure 7 It is a structural schematic diagram of the constant pressure component in the present invention;

[0032] Figure 8 It is a structural schematic diagram of the fixing frame component in the present invention.

[0033] [Reference Signs]

[0034] In the picture:

[0035] 1. Fixed frame component; 2. Collection component; 3. Medicine storage bottle; 4. First filter; 5. Constant pressure component; 11. Base plate; 12. Guide rail; 13. Rotating rod; 14. Arc support frame; 15. Rotating block; 16. Locking piece; 21. Bellows; 22. Cover; 23. Base; 24. Lifting cylinder; 25. Moving bracket; 26. First screw; 27. Center rod; 28. Blood bag; 41. Second filter; 51. Upper shell; 52. Lower shell; 53. Sealing ball; 54. First spring; 101. Main Pipeline; 102, injection head; 141, second screw; 151, first pipe; 152, second pipe; 153, third pipe; 221, sealing ring; 222, connecting interface; 231, support member; 232, third screw; 233, first gear; 234, second gear; 235, turning handle; 236, moving plate; 241, stopper; 261, threaded sleeve; 271, second spring; 272, sliding plate; 273, limit plate; 274, through groove; 501, input pipe; 502, output pipe.

[0036] As shown in the figure, in order to clearly implement the structure of the embodiment of the present invention, specific structures and devices are marked in the figure, but this is only for illustrative purposes and is not intended to limit the present invention to the specific structure, device and environment. According to specific needs, ordinary technicians in this field can adjust or modify these devices and environments. DETAILED DESCRIPTION

[0037] The present invention is described in detail below with reference to the accompanying drawings and specific embodiments. It is also noted that, to provide a more detailed description, the following embodiments are best and preferred embodiments, and those skilled in the art may employ alternative methods for implementing certain known technologies. Furthermore, the accompanying drawings are intended only to provide a more detailed description of the embodiments and are not intended to limit the present invention.

[0038] It should be noted that references in the specification to "one embodiment," "an embodiment," "exemplary embodiments," "some embodiments," etc. indicate that the described embodiments may include specific features, structures, or characteristics, but not necessarily every embodiment will include such specific features, structures, or characteristics. Furthermore, when specific features, structures, or characteristics are described in conjunction with an embodiment, it is within the knowledge of persons skilled in the relevant art to implement such features, structures, or characteristics in conjunction with other embodiments (whether or not explicitly described).

[0039] In general, terms can be understood, at least in part, from their use in context. For example, depending at least in part on the context, the term "one or more" as used herein can be used to describe any feature, structure, or characteristic in the singular sense, or can be used to describe a combination of features, structures, or characteristics in the plural sense. Additionally, the term "based on" can be understood as not necessarily intended to convey an exclusive set of factors, but can instead, depending at least in part on the context, allow for the presence of other factors that are not necessarily explicitly described.

[0040] It will be understood that the meanings of “on,” “over,” and “above” in the present invention should be interpreted in the broadest manner, so that “on” means not only “directly on” something but also includes the meaning of being “on” something with intervening features or layers, and “on” or “above” means not only “on” or “above” something but also includes the meaning of being “on” or “above” something with no intervening features or layers.

[0041] Additionally, spatially relative terms such as "below," "beneath," "lower," "above," and "upper" may be used herein for descriptive convenience to describe the relationship of one element or feature to another element or features, as illustrated in the accompanying drawings. Spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the accompanying drawings. The device may be oriented in other ways, and the spatially relative descriptors used herein should be similarly interpreted accordingly.

[0042] like Figures 1 to 8 As shown, an embodiment of the present invention provides a bone marrow blood collection and filtration device, including a fixed frame component 1, a main pipeline 101 and an injection head 102 are detachably connected to the fixed frame component 1, the main pipeline 101 is also detachably connected to a medicine storage bottle 3 through an injection pipeline, the interior of the medicine storage bottle 3 is filled with heparin solution, a constant pressure component 5 is installed on the injection pipeline, and a collection component 2 is detachably installed at one end of the main pipeline 101 away from the fixed frame component 1, and the collection component 2 can automatically collect spinal cord blood. A plurality of evenly distributed first filters 4 are installed in series on the main pipeline 101, and each first filter 4 is connected in parallel. There is a second filter 41, and a constant pressure component 5 is connected between the input end of the second filter 41 and the main pipeline 101. The constant pressure component 5 is used to limit the pressure at various locations inside the main pipeline 101. The collection component 2 includes a bellows 21, and a blood storage bag 28 is provided inside the bellows 21. The top of the bellows 21 is detachably installed with a cover body 22, and the bottom end of the bellows 21 is integrally formed with a base 23. A connection interface 222 is fixedly installed in the middle of the cover body 22, and the lower end of the connection interface 222 extends into the interior of the bellows 21. The blood storage bag 28 is detachably connected to the lower end of the connection interface 222.

[0043] Before bone marrow blood collection, nurses need to prepare a large number of syringes with heparinized solution, depending on the amount of marrow to be collected. After preparation, the physician first administers local anesthesia at the site to be punctured. The physician then inserts the bone marrow collection needle into the bone marrow cavity (typically the posterior superior iliac spine). The heparinized syringe is then connected to the needle, and the bone marrow collection is then manually aspirated. The amount collected varies depending on the patient's weight, and each aspiration requires a new syringe, placing a high level of dependency on medical personnel. Furthermore, because the aspirated bone marrow blood contains impurities such as clots, white blood cells, fat droplets, and bone particles, the collected blood must undergo a secondary filtration procedure to obtain relatively pure hematopoietic stem cells. Currently, this clinical procedure is cumbersome, and the bone marrow filtration process carries the risk of exposure and contamination.

[0044] During use, medical staff locate and perform local anesthesia at the position of the donor's posterior superior iliac spine, and then puncture with a marrow collection needle. After the puncture is completed, the marrow collection needle sheath is retained, the needle core is removed, and the syringe on the injection head 102 is connected to the marrow collection needle sheath. At this time, the collection component 2 is pressed to make the collection component 2 work. When the collection component 2 works, it can generate suction, and then the bone marrow blood can be sucked into the interior of the blood storage bag 28 along the main pipeline 101. Because of the suction effect of the collection component 2, the interior of the main pipeline 101 will be in a negative pressure state. Therefore, during the suction process, the constant pressure component 5 connected to the medicine storage bottle 3 is opened, so that the heparin solution inside the medicine storage bottle 3 can be automatically sucked. The bone marrow blood is sucked and flows through the multi-stage first filter 4 to be filtered to obtain relatively pure hematopoietic stem cells. Therefore, the present device can realize automatic collection of bone marrow blood without repeated replacement of syringes, thereby reducing dependence on medical staff.

[0045] like Figures 2 to 5 As shown, a plurality of center rods 27 distributed in a ring are fixedly installed on the upper surface of the base 23, and a plurality of lifting cylinders 24 corresponding to the center rods 27 are fixedly installed on the cover body 22. A second spring 271 is sleeved on the outer side of the center rod 27, and two mutually symmetrical support members 231 are installed on the upper surface of the base 23. A third screw 232 is rotatably installed between the support member 231 and the base 23, and a first gear 233 is fixedly installed on the bottom end of the third screw 232. A second gear 234 is rotatably installed in the middle of the upper surface of the base 23, and the second gear 234 is connected to the two first gears 233 through a rack belt. A movable plate 236 is provided on both sides of the second gear 234, and a plurality of center rods 27 are respectively slidably clamped on the corresponding movable plates 236, and the second spring 271 is clamped by the sliding plate 272 and the movable plate 236.

[0046] When the collection component 2 is pressed, the bellows 21 is deformed, and the lifting cylinder 24 drives the sliding plate 272 to descend. The descent of the sliding plate 272 will squeeze the second spring 271, and the center rod 27 will enter the interior of the lifting cylinder 24. At this time, the main pipeline 101 is connected to the connecting interface 222, and then the medical staff releases their hands. A one-way valve for exhausting air is installed on the cover body 22. Under the action of the second spring 271, the cover body 22 and the base 23 will move away from each other, thereby generating negative pressure. The negative pressure will be transmitted to the injection head 102 position along the main pipeline 101, and then bone marrow blood can be collected.

[0047] The lifting cylinder 24 is made of transparent material, and each lifting cylinder 24 is engraved with scale lines on its inner wall. A plurality of sealing rings 221 corresponding to the lifting cylinder 24 are fixedly installed on the upper surface of the cover 22. The sealing rings 221 are sealed and movable sleeves are arranged on the outer surface of the corresponding lifting cylinder 24. The outer sliding sleeve of the center rod 27 is provided with a sliding plate 272. The top of the second spring 271 is fixedly installed with a limit plate 273. The limit plate 273 is located inside the lifting cylinder 24. A plurality of evenly distributed through grooves 274 are opened on the sliding plate 272. The interior of the lifting cylinder 24 is fixedly installed with a plurality of sets of Evenly distributed blocks 241, the number of each group of blocks 241 corresponds to the number of through slots 274, a movable bracket 25 is provided above the cover body 22, and multiple lifting cylinders 24 are rotatably mounted on the movable bracket 25, and multiple evenly distributed first screws 26 are also rotatably mounted on the movable bracket 25. A plurality of threaded sleeves 261 corresponding to the first screws 26 are fixedly mounted on the cover body 22, and the first screw 26 is clamped inside the threaded sleeve 261 through a threaded clamp, and a turning handle 235 is rotatably installed in the middle of the lower surface of the base 23, and the turning handle 235 is fixedly connected to the second gear 234.

[0048] Because the people and body systems of patients who absorb bone marrow blood are different, excessive absorption pressure may cause discomfort to patients. When the absorption pressure needs to be adjusted, the handle 235 can be turned. The handle 235 will drive the second gear 234 to rotate. When the second gear 234 rotates, the two first gears 233 will be driven to rotate through the rack belt. The rotation of the first gear 233 will drive the third screw 232 to rotate, and the rotation of the third screw 232 will cause the movable plate 236 to move up and down, thereby compressing the center rod 27, changing the thrust generated by the second spring 271, and thus changing the absorption force. Before use, a part of the lifting cylinder 24 can be rotated to make the block 2 41 is on the same vertical line as the through slot 274. When pressing down, a part of the block 241 will pass through the through slot 274, and thus no thrust will be generated on the sliding plate 272. That is, when the cover body 22 is pressed down, a part of the second spring 271 will not be compressed and will enter the interior of the lifting cylinder 24 together with the center rod 27, which can change the number of the second springs 271 applying force. Furthermore, by arranging the movable plate 236 and the lifting cylinder 24, the device has a multi-stage pressure regulating mechanism, which can quickly and conveniently adjust the suction pressure according to the user. The device has a simple structure and is easy to use, which makes the suction operation smoother and reduces the discomfort caused to the patient.

[0049] Because the amount of bone marrow blood collected from each patient is different according to his or her weight, the present device is provided with a lifting cylinder 24. When the extraction amount needs to be changed, it is only necessary to rotate all the lifting cylinders 24 first so that the stopper 241 is aligned with the through groove 274, and then rotate the first screw 26. Rotating the first screw 26 will lower the movable bracket 25, and the lowering of the movable bracket 25 will drive all the lifting cylinders 24 to move downward. Observe the scale line on the lifting cylinder 24. When the scale reaches the required value, stop rotating the first screw 26. At this time, all the lifting cylinders 24 are reversed back to their original positions. At this time, the stopper 241 is staggered with the through groove 274. At this time, the cover body 22 is pressed to reach its maximum position. At this time, the center rod 27 will press the lifting cylinder 24, that is, the amount of air discharged. Under the action of the second spring 271, the cover body 22 will rebound to its original position, and then an equal amount of bone marrow blood will be drawn through the main pipeline 101, which can conveniently adjust the absorption amount and realize quantitative absorption. There is no need to repeatedly replace the syringe for absorption.

[0050] like Figure 7As shown, the constant pressure component 5 includes an upper shell 51 and a lower shell 52. The upper shell 51 and the lower shell 52 are combined to form a closed chamber. The lower shell 52 is sleeved on the end of the upper shell 51 by threaded fitting. An input pipe 501 is fixedly installed in the middle of the upper shell 51, and an output pipe 502 is fixedly installed in the middle of the lower shell 52. Both the input pipe 501 and the output pipe 502 are connected to the closed chamber. The input pipe 501 extends into the interior of the closed chamber. A first spring 54 is fixedly installed inside the lower shell 52. A sealing ball 53 is fixedly installed on the first spring 54. The sealing ball 53 is pushed against the input pipe 501 by the first spring 54.

[0051] During use, the patient's pathological reactions may cause the white blood cell concentration in the bone marrow blood to increase, resulting in a decrease in the concentration of the bone marrow blood. This will cause the bone marrow blood to generate greater pressure when passing through the main pipe 101. The first filter 4 may be blocked by the high-concentration bone marrow blood, making the collection work difficult. Therefore, the device connects multiple second filters 41 in parallel, connects the input pipe 501 to the corresponding input end of the first filter 4, and connects the output pipe 502 to the corresponding input end of the second filter 41. During normal use, the sealing ball 53 will be closed under the action of the first spring 54. The input tube 501 is blocked, so that the bone marrow blood cannot pass through the second filter 41. However, when a first filter 4 is blocked, the pipe pressure at the connection between it and the next first filter 4 will increase, and the pipe pressure between it and the previous first filter 4 will remain unchanged. At this time, the bone marrow blood will push the sealing ball 53 from the input tube 501 under the action of suction and enter the interior of the upper shell 51. The bone marrow blood will then pass through the corresponding second filter 41 along the output tube 502. When blockage occurs, the bone marrow blood flow through the pipe can be automatically and quickly replaced to prevent abnormalities in bone marrow blood collection caused by pipe blockage.

[0052] like Figure 8 As shown, the fixed frame component 1 includes a base plate 11, and guide rails 12 are fixedly installed on the upper surfaces of both ends of the base plate 11. A slider is provided inside the guide rail 12 for sliding movement, and a rotating rod 13 is rotatably installed on the upper surface of the slider. An arc-shaped support frame 14 is provided above the fixed frame component 1, and a second screw 141 is fixedly installed on both ends of the arc-shaped support frame 14. The second screw 141 is fixedly mounted on the inner part of the rotating rod 13 through threaded engagement, and a locking member 16 for fixing the position is installed on the slider. A rotating block 15 is rotatably installed on the middle part of the arc-shaped support frame 14, and a first pipe 151, a second pipe 152, and a third pipe 153 are fixedly installed on the rotating block 15. The second pipe 152, the first pipe 151, and the third pipe 153 are connected in sequence. The medicine storage bottle 3 is detachably connected to the third pipe 153 through the injection pipe, the main pipe 101 is detachably connected to the first pipe 151, and the injection head 102 is detachably connected to the second pipe 152.

[0053] During actual use, the patient is first placed between the arc-shaped support frame 14 and the seat plate 11, and then the injection head 102 is installed with the second pipe 152, the main pipe 101 is installed with the first pipe 151, and the medicine storage bottle 3 is installed with the third pipe 153. The horizontal position of the arc-shaped support frame 14 is adjusted by sliding the rotating rod 13, and then the position is limited by using the locking member 16, and then the rotating rod 13 is rotated to adjust the vertical height of the arc-shaped support frame 14. Finally, the injection head 102 is connected to the patient's spine. The rest of the device can be placed directly on the bed.

[0054] The specific working process of the technical solution provided by the present invention is as follows:

[0055] During use, the medical staff first performs local anesthesia on the area where puncture is required, and then punctures the bone marrow collection needle into the bone marrow cavity (generally the posterior superior iliac spine). After the puncture is completed, the sheath of the bone marrow collection needle is retained, the needle core is removed, and the syringe on the injection head 102 is connected to the sheath of the bone marrow collection needle. At this time, the collection component 2 is pressed to make the collection component 2 work. When the collection component 2 works, it can generate suction, and then the bone marrow blood can be sucked into the interior of the blood storage bag 28 along the main pipeline 101. Due to the suction effect of the collection component 2, the interior of the main pipeline 101 will be in a negative pressure state. Therefore, during the suction process, the constant pressure component 5 connected to the medicine storage bottle 3 is opened, so that the heparin solution in the medicine storage bottle 3 can be automatically sucked. The bone marrow blood is sucked and flows through the multi-stage first filter 4 to be filtered to obtain relatively pure hematopoietic stem cells. Therefore, the present device can realize automatic collection of bone marrow blood without the need to repeatedly replace the syringe, thereby reducing dependence on medical staff;

[0056] Because the people and body systems of patients who absorb bone marrow blood are different, excessive absorption pressure may cause discomfort to patients. When the absorption pressure needs to be adjusted, the handle 235 can be turned. The handle 235 will drive the second gear 234 to rotate. When the second gear 234 rotates, the two first gears 233 will be driven to rotate through the rack belt. The rotation of the first gear 233 will drive the third screw 232 to rotate, and the rotation of the third screw 232 will cause the movable plate 236 to move up and down, thereby compressing the center rod 27, changing the thrust generated by the second spring 271, and thus changing the absorption force. Before use, a part of the lifting cylinder 24 can be rotated to make the block 2 41 is on the same vertical line as the through slot 274. When pressing down, a part of the block 241 will pass through the through slot 274, and thus no thrust will be generated on the sliding plate 272. That is, when the cover body 22 is pressed down, a part of the second spring 271 will not be compressed and will enter the interior of the lifting cylinder 24 together with the center rod 27, which can change the number of the second springs 271 applying force. Furthermore, by arranging the movable plate 236 and the lifting cylinder 24, the device has a multi-stage pressure regulating mechanism, which can quickly and conveniently adjust the suction pressure according to the user. The device has a simple structure and is easy to use, which makes the suction operation smoother and reduces the discomfort caused to the patient.

[0057] The above description is merely a preferred embodiment of the present invention; however, the scope of protection of the present invention is not limited thereto. Any person skilled in the art who, within the technical scope disclosed by the present invention, makes equivalent substitutions or modifications based on the technical solutions and improved concepts of the present invention shall be covered by the scope of protection of the present invention.

Claims

1. A bone marrow blood collection and filtration device, comprising a fixing frame component, characterized in that: The fixing frame component is detachably connected with a main pipeline and an injection head, the main pipeline is also detachably connected with a medicine storage bottle through an injection pipeline, the interior of the medicine storage bottle is filled with heparin solution, a constant pressure component is installed on the injection pipeline, and a collection component is detachably installed on one end of the main pipeline away from the fixing frame component, the collection component can automatically collect spinal cord blood, a plurality of evenly distributed first filters are installed in series on the main pipeline, each of the first filters is connected in parallel with a second filter, and a constant pressure component is connected between the input end of the second filter and the main pipeline, and the constant pressure component is used to limit the pressure at various locations inside the main pipeline; The collecting component comprises a bellows, a cover body is detachably mounted on the top end of the bellows, a base is integrally formed on the bottom end of the bellows, a plurality of center rods distributed in a ring are fixedly mounted on the upper surface of the base, a second spring is sleeved on the outside of the center rods, a plurality of lifting cylinders corresponding to the center rods are fixedly mounted on the cover body, and a blood storage bag is arranged inside the bellows.

2. The bone marrow blood collection and filtration device according to claim 1, characterized in that: The outer sliding sleeve of the center rod is provided with a sliding plate, the top end of the second spring is fixedly installed with a limit plate, the limit plate is located inside the lifting cylinder, a plurality of evenly distributed through grooves are opened on the sliding plate, and a plurality of groups of evenly distributed blockers are fixedly installed inside the lifting cylinder, and the number of blockers in each group corresponds to the number of through grooves.

3. The bone marrow blood collection and filtration device according to claim 2, characterized in that: A movable bracket is provided above the cover body, and the multiple lifting cylinders are rotatably installed on the movable bracket. A plurality of evenly distributed first screws are also rotatably installed on the movable bracket. A plurality of threaded sleeves corresponding to the first screws are fixedly installed on the cover body, and the first screws are clamped inside the threaded sleeves through threads.

4. The bone marrow blood collection and filtration device according to claim 3, characterized in that: Two mutually symmetrical support members are installed on the upper surface of the base, and a third screw is rotatably installed between the support member and the base, and a first gear is fixedly installed on the bottom end of the third screw, and a second gear is rotatably installed in the middle of the upper surface of the base, and the second gear is connected to the two first gears through a rack belt, and movable plates are provided on both sides of the second gear, and multiple center rods are slidably clamped on the corresponding movable plates respectively, and the second spring is clamped by the sliding plate and the movable plate, and a turning handle is rotatably installed in the middle of the lower surface of the base, and the turning handle is fixedly connected to the second gear.

5. The bone marrow blood collection and filtration device according to claim 4, characterized in that: The constant pressure component includes an upper shell and a lower shell, which are combined to form a closed chamber. The lower shell is sleeved on the end of the upper shell by threaded fitting. An input pipe is fixedly installed in the middle of the upper shell, and an output pipe is fixedly installed in the middle of the lower shell. Both the input pipe and the output pipe are connected to the closed chamber, and the input pipe extends into the inside of the closed chamber. A first spring is fixedly installed inside the lower shell, and a sealing ball is fixedly installed on the first spring. The sealing ball is pushed against the input pipe by the first spring.

6. The bone marrow blood collection and filtration device according to claim 5, characterized in that: The fixed frame component includes a seat plate, guide rails are fixedly installed on the upper surfaces of both ends of the seat plate, a slider is slidably clamped inside the guide rail, a rotating rod is rotatably installed on the upper surface of the slider, an arc-shaped support frame is provided above the fixed frame component, second screws are fixedly installed on both ends of the arc-shaped support frame, the second screws are clamped inside the rotating rod through threaded engagement, and a locking piece for fixing the position is installed on the slider.

7. The bone marrow blood collection and filtration device according to claim 6, characterized in that: The lifting cylinder is made of transparent material, and scale lines are engraved on the inner wall of each lifting cylinder.

8. The bone marrow blood collection and filtration device according to claim 7, characterized in that: A connection interface is fixedly installed in the middle of the cover body, and the lower end of the connection interface extends into the interior of the bellows. The blood storage bag is detachably connected to the lower end of the connection interface.

9. The bone marrow blood collection and filtration device according to claim 8, characterized in that: A plurality of sealing rings corresponding to the lifting cylinder are fixedly mounted on the upper surface of the cover body, and the sealing rings are sealingly sleeved on the outer surface of the corresponding lifting cylinder.

10. The bone marrow blood collection and filtration device according to claim 9, characterized in that: A rotating block is rotatably installed in the middle of the arc-shaped support frame, and a first pipe, a second pipe, and a third pipe are fixedly installed on the rotating block. The second pipe, the first pipe, and the third pipe are connected in sequence, the medicine storage bottle is detachably connected to the third pipe through the injection pipe, the main pipe is detachably connected to the first pipe, and the injection head is detachably connected to the second pipe.

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