Traditional Chinese medicine compound cosmetic with whitening effect and preparation technology of traditional Chinese medicine compound cosmetic

Abstract

The invention belongs to the technical field of traditional Chinese medicine compound cosmetics, and provides a traditional Chinese medicine compound cosmetic with a whitening effect and a preparation technology thereof. The traditional Chinese medicine compound cosmetic is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of liquorice, 5-15 parts of ginseng, 5-12 parts of astragalus membranaceus, 5-15 parts of radix paeoniae alba, 5-15 parts of white mulberry root-bark, 5-10 parts of ligusticum wallichii, 5-30 parts of poria cocos, 5-30 parts of bighead atractylodes rhizome and 5-30 parts of pearl. The medicinal materials are grouped, the poria cocos, the rhizoma atractylodis macrocephalae and the pearls are divided into four groups, the first combination is mixed with the four groups respectively, then through activity inhibition experiments of the poria cocos, the rhizoma atractylodis macrocephalae and the pearls on tyrosinase, the rhizoma atractylodis macrocephalae, the poria cocos and the pearls are added into the first combination respectively, and the inhibition effect on the tyrosinase activity is improved; bighead atractylodes rhizome, poria cocos and pearl are added at the same time, the inhibition effect on tyrosinase activity is the highest, and therefore the whitening effect is more remarkable.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine compound cosmetics, in particular to a traditional Chinese medicine compound cosmetic with whitening effect and a preparation technology thereof. Background Art

[0002] Melanocytes in the basal layer of the human epidermis are the site of melanin production. After melanin is produced, it is transferred from the dendrite tips of melanocytes to the stratum corneum and excreted with the metabolism of stratum corneum cells. The number of melanocytes, the degree of dendrites, the activity of related enzymes and the transfer of melanosomes will all affect pigmentation. Excessive production and accumulation of melanin in the skin can cause dark spots, chloasma, freckles and malignant melanoma. Among them, the main causes of facial melanin formation include physiological factors, endocrine disorders, melanopathy and other reasons.

[0003] The whitening prescription of traditional Chinese medicine uses the method of clearing away heat and detoxifying to reduce skin pigmentation and has the effect of whitening the skin. Traditional Chinese medicine whitening can make the skin more even, rosy, and elastic. The whitening effect is better than other methods and has no side effects on the body. It also has a certain improvement effect on melanin deposition caused by insufficient qi and blood.

[0004] However, since tyrosinase is the key rate-limiting enzyme in melanin biosynthesis, inhibiting the tyrosinase content can effectively limit the synthesis of melanin. However, the existing Chinese medicine whitening prescriptions have a low inhibitory effect on the activity of tyrosinase, resulting in an insufficiently obvious whitening effect.

[0005] To this end, those skilled in the art have proposed a Chinese herbal compound cosmetic with whitening effect and a preparation technology thereof to solve the problems raised by the background technology. Summary of the invention

[0006] In order to solve the above technical problems, the present invention provides a Chinese herbal compound cosmetic with whitening effect and a preparation technology thereof, which significantly improves the inhibitory effect on tyrosinase activity, thereby making the whitening effect more obvious.

[0007] To achieve the above object, the present invention provides the following technical solutions:

[0008] A traditional Chinese medicine compound cosmetic with whitening effect, which is prepared from the following traditional Chinese medicine raw materials by weight: 10-30 parts of liquorice, 5-15 parts of ginseng, 5-12 parts of astragalus, 5-15 parts of white peony root, 5-15 parts of mulberry bark, 5-10 parts of chuanxiong, 5-30 parts of tuckahoe, 5-30 parts of atractylodes, and 5-30 parts of pearl;

[0009] Preferably, the Chinese herbal compound cosmetic is prepared from the following Chinese herbal raw materials in parts by weight: 30 parts of licorice, 15 parts of ginseng, 12 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong, and 20 parts of poria.

[0010] Preferably, the Chinese herbal compound cosmetic is prepared from the following Chinese herbal raw materials in parts by weight: 30 parts of licorice, 15 parts of ginseng, 12 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong, and 20 parts of atractylodes.

[0011] Preferably, the Chinese herbal compound cosmetic is prepared from the following Chinese herbal raw materials in parts by weight: 30 parts of licorice, 15 parts of ginseng, 12 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong, and 20 parts of pearls.

[0012] Preferably, the Chinese herbal compound cosmetic is prepared from the following Chinese herbal raw materials in parts by weight: 30 parts of licorice, 5 parts of ginseng, 10 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong, 10 parts of atractylodes, 30 parts of poria, and 5 parts of pearl.

[0013] A preparation technology of a Chinese medicinal compound cosmetic with whitening effect, the preparation technology method of the Chinese medicinal compound cosmetic with whitening effect comprises the following steps:

[0014] Step 1: Select materials, select high-quality medicinal materials from the above medicinal materials as raw materials;

[0015] Step 2: washing and drying, washing licorice, ginseng, astragalus, white peony root, mulberry bark, chuanxiong, poria, and atractylodes, and then drying the washed medicinal materials at low temperature to obtain dried medicinal materials;

[0016] Step 3: Group the medicinal materials. Divide the dried licorice, ginseng, astragalus, white peony root, mulberry bark, and Chuanxiong into a dry combination, and divide Poria, Atractylodes macrocephala, and pearl into four groups.

[0017] Step 4: Grinding, grinding the dried composition into a fine powder of 20-100 mesh to obtain a pulverized composition, and then grinding Poria cocos, Atractylodes macrocephala and Pearl into a fine powder of 20-100 mesh;

[0018] Step 5: Mix the crushed composition with Poria cocos, Atractylodes macrocephala and Pearl, and then extract the composition. The composition is extracted by:

[0019] (1) Supercritical fluid extraction, using carbon dioxide, ethylene, ammonia, and nitrous oxide as supercritical extractants for extraction;

[0020] (2) Macroporous resin adsorption method, using D101 or AB-8 macroporous resin columns for purification and extraction;

[0021] (3) Ultrasonic extraction method, using solvent to extract under the action of ultrasonic waves;

[0022] Step 6: Then add acceptable excipients or auxiliary ingredients in medicines, health products or daily chemicals to prepare a commonly used external preparation.

[0023] Preferably, in step three of the technical method for preparing the traditional Chinese medicine compound cosmetics with whitening effect, Poria cocos, Atractylodes macrocephala and pearls are divided into four groups, namely, Poria cocos group, Atractylodes macrocephala group, pearl group and Poria cocos, Atractylodes macrocephala and pearl group.

[0024] Preferably, the macroporous resin adsorption method specifically includes the following steps: taking fine powders of licorice, white mulberry bark and astragalus, adding 5-8 times (V / m) 50%-80% ethanol according to the volume-to-mass ratio, reflux extraction 1-3 times, each extraction time 1-3 hours, filtering, combining the filtrates, reducing pressure to recover ethanol at 55-75°C until there is no alcohol taste, and then purifying on a D101 or AB-8 macroporous resin column, collecting the 40%-70% ethanol elution part, reducing pressure to recover ethanol at 60°C to obtain an extract, vacuum drying at 50-70°C, and crushing to obtain the above three medicinal extracts.

[0025] Preferably, the supercritical fluid extraction method specifically includes the following steps: selecting carbon dioxide as a supercritical extractant, taking fine powders of ginseng, white peony root and chuanxiong, placing the above raw materials in a supercritical fluid extraction kettle, and adding 50%-95% ethanol as an entrainer for supercritical fluid extraction, the entrainer dosage is 120ml-180ml / per 100g raw material, the carbon dioxide flow rate is 20-30kg / h, the extraction pressure is 20-45MPa, the extraction temperature is 40-60℃, the extraction time is 2-4h, after the extraction is completed, the pressure is reduced and discharged, the extract is collected, and it is dried and crushed to obtain the above three medicinal extracts.

[0026] Preferably, in the ultrasonic extraction method, a solvent is selected, and Poria cocos, Atractylodes macrocephala and Pearl are placed in the solvent under the action of ultrasonic waves for 30-40 minutes, and then filtered, dried and crushed to obtain the above three medicinal extracts; the solvent includes pure water, 75% ethanol and anhydrous ethanol.

[0027] Compared with the prior art, the present invention has the following beneficial effects:

[0028] The present invention divides liquorice, ginseng, astragalus, white peony root, white mulberry bark and chuanxiong into combination one, divides Poria cocos, Atractylodes macrocephala and pearl into four groups, namely, a Poria cocos group, an Atractylodes macrocephala group, a pearl group and a Poria cocos, Atractylodes macrocephala and pearl group, mixes the above four groups respectively, and then conducts an activity inhibition experiment on tyrosinase by Poria cocos, Atractylodes macrocephala and pearl, it can be known that when Atractylodes macrocephala, Poria cocos and pearl are added to the drug combination one, the inhibitory effect on tyrosinase activity is improved, and the whitening effect can be improved. Among them, when Atractylodes macrocephala, Poria cocos and pearl are added at the same time, the inhibitory effect on tyrosinase activity is the highest, so that the whitening effect is more significantly improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0030] Figure 1 The present invention is a schematic diagram of the process of preparing a traditional Chinese medicine compound cosmetic with whitening effect. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0032] As attached Figure 1 As shown:

[0033] The invention provides a traditional Chinese medicine compound cosmetic with whitening effect and a preparation technology thereof. The traditional Chinese medicine compound cosmetic is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of liquorice, 5-15 parts of ginseng, 5-12 parts of astragalus, 5-15 parts of white peony root, 5-15 parts of mulberry bark, 5-10 parts of chuanxiong, 5-30 parts of tuckahoe, 5-30 parts of atractylodes macrocephala, and 5-30 parts of pearl;

[0034] The medicinal materials were grouped. The dried licorice, ginseng, astragalus, white peony root, mulberry bark and Chuanxiong were divided into combination one. The Poria cocos, Atractylodes macrocephala and pearl were divided into four groups, namely the Poria cocos group, Atractylodes macrocephala group, pearl group and the Poria cocos, Atractylodes macrocephala and pearl group. Combination one was mixed with the above four groups.

[0035] Embodiment 1:

[0036] Specifically, the Chinese herbal compound cosmetic is prepared from the following Chinese herbal raw materials in parts by weight: 30 parts of licorice, 15 parts of ginseng, 12 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong, and 20 parts of tuckahoe.

[0037] The technical method for preparing the traditional Chinese medicine compound cosmetics with whitening effect comprises the following steps:

[0038] Step 1: Select materials, select high-quality medicinal materials from the above medicinal materials as raw materials;

[0039] Step 2: washing and drying, washing licorice, ginseng, astragalus, white peony root, mulberry bark, chuanxiong, poria, and atractylodes, and then drying the washed medicinal materials at low temperature to obtain dried medicinal materials;

[0040] Step 3: Grinding, grinding the dried composition into a fine powder of 20-100 mesh to obtain a pulverized composition, and then grinding Poria cocos, Atractylodes macrocephala and Pearl into a fine powder of 20-100 mesh;

[0041] Step 4: Mix the crushed composition with Poria cocos, Atractylodes macrocephala and Pearl, and then extract the composition. The composition is extracted by:

[0042] (1) The supercritical fluid extraction method specifically comprises the following steps: selecting carbon dioxide as a supercritical extractant, taking fine powders of ginseng, white peony root and ligusticum chuanxiong, placing the above raw materials in a supercritical fluid extraction kettle, and adding 50%-95% ethanol as an entrainer for supercritical fluid extraction, the entrainer dosage is 120ml-180ml / per 100g raw material, the carbon dioxide flow rate is 20-30kg / h, the extraction pressure is 20-45MPa, the extraction temperature is 40-60℃, the extraction time is 2-4h, after the extraction is completed, the decompression is discharged, the extract is collected, and the extract is dried and crushed to obtain the above three medicinal extracts.

[0043] (2) The macroporous resin adsorption method specifically comprises the following steps: taking fine powder of licorice, white mulberry bark and astragalus, adding 5-8 times (V / m) 50%-80% ethanol according to the volume-to-mass ratio, reflux extraction 1-3 times, each extraction time 1-3 hours, filtering, combining the filtrates, recovering ethanol under reduced pressure at 55-75°C until there is no alcohol taste, and then purifying on a D101 or AB-8 macroporous resin column, collecting the 40%-70% ethanol elution part, recovering ethanol under reduced pressure at 60°C to obtain an extract, vacuum drying at 50-70°C, and pulverizing to obtain the above three medicinal extracts.

[0044] (3) Ultrasonic extraction method: select a solvent, place Poria cocos in the solvent, and extract it under the action of ultrasound for 30-40 minutes, then filter, dry and crush to obtain the above-mentioned medicinal material extract; the solvent includes pure water, 75% ethanol and anhydrous ethanol.

[0045] Step 5: Then add the acceptable excipients or auxiliary ingredients in medicines, health products or daily chemicals to prepare a commonly used external preparation.

[0046] Embodiment 2:

[0047] This embodiment is basically the same as the previous embodiment, except that pearl preparation is added to combination one.

[0048] Specifically, the Chinese herbal compound cosmetic is prepared from the following Chinese herbal raw materials in parts by weight: 30 parts of licorice, 15 parts of ginseng, 12 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong, and 20 parts of pearls.

[0049] Step 1, step 2, step 3 and step 5 are basically the same as those in the first embodiment.

[0050] The extraction steps of ginseng, white peony root, chuanxiong, liquorice, mulberry bark and astragalus are the same as those in Example 1.

[0051] Only when using the ultrasonic extraction method will the material be replaced with pearls, specifically: select a solvent, place the pearls in the solvent, under the action of ultrasonic waves for 30-40 minutes, then filter, dry and crush to obtain the above-mentioned medicinal extract.

[0052] Embodiment three:

[0053] This embodiment is basically the same as the previous embodiment, except that Atractylodes macrocephala is added to the combination one.

[0054] Specifically, the Chinese herbal compound cosmetic is prepared from the following Chinese herbal raw materials in parts by weight: 30 parts of licorice, 15 parts of ginseng, 12 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong, and 20 parts of atractylodes.

[0055] Step 1, step 2, step 3 and step 5 are basically the same as those in the first embodiment.

[0056] The extraction steps of ginseng, white peony root, chuanxiong, liquorice, mulberry bark and astragalus are the same as those in Example 1.

[0057] Only when using the ultrasonic extraction method will the material be replaced with Atractylodes macrocephala, specifically: select a solvent, place Atractylodes macrocephala in the solvent, under the action of ultrasonic waves for 30-40 minutes, then filter, dry and crush to obtain the above medicinal extract.

[0058] Embodiment 4:

[0059] This embodiment is basically the same as the previous embodiment, except that Poria cocos, Atractylodes macrocephala and Pearl are added to the preparation of combination one.

[0060] Specifically, the Chinese herbal compound cosmetic is prepared from the following Chinese herbal raw materials in parts by weight: 30 parts of licorice, 5 parts of ginseng, 10 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong, 10 parts of atractylodes, 30 parts of poria, and 5 parts of pearl.

[0061] Step 1, step 2, step 3 and step 5 are basically the same as those in the first embodiment.

[0062] Step 4: Mix the crushed composition with Poria cocos, Atractylodes macrocephala and Pearl, and then extract the composition. The composition is extracted by:

[0063] (1) The supercritical fluid extraction method specifically includes the following steps: selecting carbon dioxide as a supercritical extractant, taking fine powders of ginseng, white peony root and ligusticum chuanxiong, placing the above raw materials in a supercritical fluid extraction kettle, and adding 85% ethanol as an entrainer for supercritical fluid extraction, the entrainer dosage is 150 ml / per 100 g raw material, the carbon dioxide flow rate is 30 kg / h, the extraction pressure is 35 MPa, the extraction temperature is 40-60°C, the extraction time is 2-4 hours, after the extraction is completed, the decompression is discharged, the extract is collected, and the extract is dried and crushed to obtain the above three medicinal extracts.

[0064] (2) The macroporous resin adsorption method specifically comprises the following steps: taking fine powder of licorice, white mulberry bark and astragalus, adding 6 times (V / m) 70% ethanol according to the volume-to-mass ratio, reflux extraction 3 times, each extraction time for 2 hours, filtering, combining the filtrates, recovering ethanol under reduced pressure at 70°C until there is no alcohol taste, and then purifying on a D101 or AB-8 macroporous resin column, collecting the 60% ethanol elution part, recovering ethanol under reduced pressure at 60°C to obtain an extract, vacuum drying at 60°C, and pulverizing to obtain the extracts of the above three medicinal materials.

[0065] (3) Ultrasonic extraction method: select a solvent, place Poria cocos, Atractylodes macrocephala and Pearl in the solvent, and place under the action of ultrasound for 30 minutes, then filter, dry and crush to obtain the extracts of the above three medicinal materials; the solvent includes pure water, 75% ethanol and anhydrous ethanol.

[0066] From the above, it can be seen that licorice, ginseng, astragalus, white peony root, mulberry bark, and Chuanxiong were mixed and prepared into Poria group, Atractylodes group, pearl group, and Poria, Atractylodes and pearl group, and then the inhibitory effects on tyrosinase activity were compared.

[0067] Embodiment five:

[0068] This example relates to an experiment on the inhibition of tyrosinase activity by Poria cocos, Atractylodes macrocephala and Pearl.

[0069] The experimental steps are as follows:

[0070] 1. Samples: Poria cocos, Atractylodes macrocephala and pearl, vitamin C and α-arbutin as positive control group;

[0071] There are four sample groups, namely, Poria cocos group, Atractylodes macrocephala group, Pearl group, and Poria cocos, Atractylodes macrocephala and Pearl group;

[0072] 2. Preparation of test solution: Vitamin C and α-arbutin were added with pure water to prepare test solution; Poria cocos, Atractylodes macrocephala and pearl were weighed, and three solvents with different polarities (pure water, 75% ethanol, anhydrous ethanol) were used for ultrasonic extraction, and the material ratio was 1:15. After ultrasonic extraction for 30 minutes, the filter was filtered, and the residue was extracted again according to the above method. The filtrates were combined to prepare the test solution, and the solution was diluted as the test solution for tyrosinase powder inhibition test;

[0073] 3. Preparation of substrate tyrosinase solution: Add tyrosinase powder into pure water to prepare tyrosinase solution;

[0074] 4. Tyrosinase activity inhibition experiment

[0075] (1) The test solution is added according to the following settings and placed in a centrifuge tube for later use;

[0076] Blank group: pure water + tyrosinase solution;

[0077] Positive control group: vitamin C solution + tyrosinase solution, α-arbutin solution + 50 μL tyrosinase solution;

[0078] Pure water extraction group: test solution + tyrosinase solution;

[0079] 75% ethanol extraction group: test solution + tyrosinase solution;

[0080] Anhydrous ethanol extraction group: test solution + tyrosinase solution.

[0081] (2) After the spectrophotometer is preheated for 30 minutes, the wavelength is adjusted to 475 nm, the pure water is adjusted to zero, and reagent 1 (the main component is the substrate that can react with tyrosinase) is added to the above test solution. The timing is immediately started, and the absorbance at 475 nm is measured at 10 seconds (total time); the reaction is continued at room temperature for 180 seconds, and the absorbance at 475 nm is measured at 190 seconds (total time); each group of test solutions is tested 5 times for data analysis. The inhibition rate of tyrosinase is calculated according to the following formula:

[0082]

[0083] Wherein, A is the absorbance value at 475nm of the blank group at 10s (total time); B is the absorbance value at 475nm of the blank group at 190s (total time); C is the absorbance value at 475nm of the test solution group at 10s (total time); D is the absorbance value at 475nm of the test solution group at 10s (total time).

[0084] 5. Experimental results

[0085] The positive control group (vitamin C and α-arbutin) and four sample groups were extracted with pure water, 75% ethanol, and anhydrous ethanol to obtain the test solutions. The results of the inhibition rate of tyrosinase activity are shown in Table 1 below.

[0086] Serial number Pure water / % 75% ethanol / % Anhydrous ethanol / % Vitamin C 95.13 α-Arbutin 55.34 Poria 66.36 80.61 74.45 pearl 61.25 70.53 66.82 Atractylodes macrocephala 52.96 69.54 58.77 Poria, Atractylodes macrocephala, Pearl 82.20 96.11 87.56

[0087] Table 1 Comparison of the inhibition rate of tyrosinase activity of sample groups under different solvents

[0088] As shown in Table 1, compared with the blank control group, all the test solutions in the positive control group, pure water extraction group, 75% ethanol extraction group, and anhydrous ethanol extraction group inhibited the activity of tyrosinase. Among them, the inhibition rate of the vitamin C group was as high as 95.13%, and that of α-arbutin was 55.34%.

[0089] Except for the Atractylodes macrocephala group, the inhibition rates of the other groups in the pure water extraction group were higher than those of the α-arbutin control group, but lower than the inhibition level of the vitamin C control group. The best inhibition rate was in the Atractylodes macrocephala, Poria cocos, and Pearl group, which was 82.20%.

[0090] The inhibition rates of the four sample groups extracted with 75% ethanol were all higher than that of the α-arbutin control group, among which the best inhibition rate was 96.11% in the Atractylodes macrocephala, Poria cocos, and Pearl group, while the other three sample groups were all lower than that in the vitamin C control group.

[0091] The inhibition rates of the four sample groups in the anhydrous ethanol extraction group were all higher than those in the α-arbutin control group, but lower than those in the vitamin C control group. The best inhibition rate was in the Atractylodes macrocephala, Poria cocos, and Pearl group, which was 87.56%.

[0092] In summary, under different extraction solvents, the inhibition rates of the sample groups are as follows: 75% ethanol extraction group > anhydrous ethanol extraction group > pure water extraction group. It can be seen that in the preparation method of the Chinese herbal compound cosmetics with whitening efficacy, the addition of Atractylodes macrocephala, Poria cocos, and pearls to the drug combination 1 respectively improves the inhibitory effect on tyrosinase activity. Among them, the addition of Atractylodes macrocephala, Poria cocos, and pearls at the same time, and under the extraction of 75% ethanol, has the highest inhibitory effect on tyrosinase activity, thereby making the whitening effect more significant.

[0093] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It is obvious to those skilled in the art that the present invention is limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic characteristics of the present invention. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims are included in the present invention. Any figure mark in the claims should not be regarded as limiting the claim involved.

[0094] The embodiments of the present invention are provided for the purpose of illustration and description. Although the embodiments of the present invention have been shown and described above, it can be understood that the above embodiments are exemplary and cannot be understood as limitations of the present invention. Ordinary technicians in this field can change, modify, replace and modify the above embodiments within the scope of the present invention.

Claims

1. A Chinese medicinal compound cosmetic with whitening effect, characterized in that: The traditional Chinese medicine compound cosmetic is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of liquorice, 5-15 parts of ginseng, 5-12 parts of astragalus, 5-15 parts of white peony root, 5-15 parts of mulberry bark, 5-10 parts of chuanxiong, 5-30 parts of tuckahoe, 5-30 parts of atractylodes macrocephala and 5-30 parts of pearl.

2. A Chinese medicinal compound cosmetic with whitening effect as claimed in claim 1, characterized in that: The Chinese medicinal compound cosmetic is prepared from the following Chinese medicinal raw materials in parts by weight: 30 parts of licorice, 15 parts of ginseng, 12 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong, and 20 parts of tuckahoe.

3. A Chinese medicinal compound cosmetic with whitening effect as claimed in claim 1, characterized in that: The Chinese medicinal compound cosmetic is prepared from the following Chinese medicinal raw materials in parts by weight: 30 parts of liquorice, 15 parts of ginseng, 12 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong and 20 parts of atractylodes.

4. A Chinese medicinal compound cosmetic with whitening effect as claimed in claim 1, characterized in that: The Chinese medicinal compound cosmetic is prepared from the following Chinese medicinal raw materials in parts by weight: 30 parts of licorice, 15 parts of ginseng, 12 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong, and 20 parts of pearls.

5. A Chinese medicinal compound cosmetic with whitening effect as claimed in claim 1, characterized in that: The Chinese medicine compound cosmetic is prepared from the following Chinese medicine raw materials in parts by weight: 30 parts of licorice, 5 parts of ginseng, 10 parts of astragalus, 15 parts of white peony root, 15 parts of mulberry bark, 10 parts of chuanxiong, 10 parts of atractylodes, 30 parts of tuckahoe, and 5 parts of pearl.

6. A preparation technology of a Chinese medicinal compound cosmetic with whitening effect, characterized in that: The technical method for preparing the traditional Chinese medicine compound cosmetics with whitening effect comprises the following steps: Step 1: Select materials, select high-quality medicinal materials from the above medicinal materials as raw materials; Step 2: washing and drying, washing licorice, ginseng, astragalus, white peony root, mulberry bark, chuanxiong, poria, and atractylodes, and then drying the washed medicinal materials at low temperature to obtain dried medicinal materials; Step 3: Group the medicinal materials. Divide the dried licorice, ginseng, astragalus, white peony root, mulberry bark, and Chuanxiong into a dry combination, and divide Poria, Atractylodes macrocephala, and pearl into four groups. Step 4: Grinding, grinding the dried composition into a fine powder of 20-100 mesh to obtain a pulverized composition, and then grinding Poria cocos, Atractylodes macrocephala and Pearl into a fine powder of 20-100 mesh; Step 5: Mix the crushed composition with Poria cocos, Atractylodes macrocephala and Pearl, and then extract the composition. The composition is extracted by: (1) Supercritical fluid extraction, using carbon dioxide, ethylene, ammonia, and nitrous oxide as supercritical extractants for extraction; (2) Macroporous resin adsorption method, using D101 or AB-8 macroporous resin columns for purification and extraction; (3) Ultrasonic extraction method, using solvent to extract under the action of ultrasonic waves; Step 6: Then add the acceptable excipients or auxiliary ingredients in medicines, health products or daily chemicals to prepare a commonly used external preparation.

7. The preparation technology of a Chinese medicinal compound cosmetic with whitening effect as claimed in claim 6, characterized in that: In step three of the technical method for preparing the traditional Chinese medicine compound cosmetics with whitening effect, Poria cocos, Atractylodes macrocephala and pearls are divided into four groups, namely, Poria cocos group, Atractylodes macrocephala group, pearl group and Poria cocos, Atractylodes macrocephala and pearl group.

8. The preparation technology of a Chinese medicinal compound cosmetic with whitening effect as claimed in claim 6, characterized in that: The macroporous resin adsorption method specifically comprises the following steps: taking fine powders of licorice, white mulberry bark and astragalus, adding 5-8 times (V / m) 50%-80% ethanol according to the volume-to-mass ratio, reflux extraction 1-3 times, each extraction time 1-3 hours, filtering, combining the filtrates, recovering ethanol under reduced pressure at 55-75°C until there is no alcohol taste, purifying on a D101 or AB-8 macroporous resin column, collecting the 40%-70% ethanol elution part, recovering ethanol under reduced pressure at 60°C to obtain an extract, vacuum drying at 50-70°C, and crushing to obtain the above three medicinal material extracts.

9. The preparation technology of a Chinese medicinal compound cosmetic with whitening effect as claimed in claim 6, characterized in that: The supercritical fluid extraction method specifically includes the following steps: selecting carbon dioxide as a supercritical extractant, taking fine powders of ginseng, white peony root and chuanxiong, placing the above raw materials in a supercritical fluid extraction kettle, and adding 50%-95% ethanol as an entrainer for supercritical fluid extraction, the entrainer dosage is 120ml-180ml / per 100g raw material, the carbon dioxide flow rate is 20-30kg / h, the extraction pressure is 20-45MPa, the extraction temperature is 40-60℃, the extraction time is 2-4h, after the extraction is completed, the decompression is discharged, the extract is collected, and it is dried and crushed to obtain the above three medicinal material extracts.

10. The preparation technology of a Chinese medicinal compound cosmetic with whitening effect as claimed in claim 6, characterized in that: The ultrasonic extraction method comprises selecting a solvent, placing Poria cocos, Atractylodes macrocephala and Pearl in the solvent, and subjecting them to ultrasonic treatment for 30-40 minutes, followed by filtering, drying and crushing to obtain the extracts of the above three medicinal materials; the solvent comprises pure water, 75% ethanol and anhydrous ethanol.

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