Compound preparation for improving laying rate of laying hens and preparation method thereof

Compound preparations made through scientific proportioning and traditional Chinese medicine fermentation process solve the problem of low egg laying rate, improve the egg laying rate and egg quality of laying hens, enhance immunity and disease resistance.

CN119453384APending Publication Date: 2025-02-18HENAN WENZHENG DONGWU PHARM CO LTD
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Patent Information

Application Number
CN202411607018.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-12
Publication Date
2025-02-18

AI Technical Summary

Technical Problem

The prior art is difficult to effectively increase the egg laying rate of laying hens, resulting in a reduction in the economic benefits of the breeding farm.

Method used

A compound preparation is used, which consists of methionine, lysine, calcium hydrogen phosphate, cod liver oil, probiotics, vitamin C, Atractylodes, Chuanxiong, Achyranthes pills, Rehmannia glutinosa, Xiangfu, wolfberry and pine needles, and is scientifically reasonable. The ratio and fermentation process of traditional Chinese medicine make it easy to absorb particles.

Benefits of technology

It significantly improves the egg laying rate and egg quality of laying hens, enhances the body's immunity and disease resistance, reduces the occurrence of broken shell eggs and deformed eggs, and improves overall health and production performance.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to a compound preparation for increasing the laying rate of laying hens. The compound preparation is mainly prepared from the following raw materials by weight: 6-8 g of methionine, 5-10 g of lysine, 3-6 g of calcium hydrophosphate, 1-3 g of cod-liver oil, 4-6 g of probiotics, 5-8 g of vitamin C, 5-8 g of bighead atractylodes rhizome, 5-8 g of ligusticum wallichii, 5-8 g of achyranthes bidentata, 5-8 g of radix rehmanniae recen, 5-8 g of rhizoma cyperi, 5-8 g of Chinese wolfberry, 6-10 g of pine needles and 100 g of a culture medium. The culture medium is prepared from 3-5 g of glucose, 1-3 g of peptone, 0.5-1.5 g of sodium chloride, 0.3-0.5 g of beef extract and purified water added to 100 g. The compound preparation is scientifically and reasonably matched according to the nutrition requirement and the body function conditioning requirement in the egg laying process of chickens, the immunity and reproductive performance of the body can be enhanced, the gastrointestinal tract is conditioned, the food consumption is increased, and growth and development are promoted.
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Description

Technical Field

[0001] The invention belongs to the technical field of feed additives, and mainly relates to a compound preparation for improving the egg production rate of laying hens and a preparation method thereof. Background Art

[0002] The egg production rate of laying hens directly affects the economic benefits of the farm. A high egg production rate means a large egg output and increased income for the farm; conversely, a low egg production rate will lead to reduced income and increased breeding costs. There are many reasons for the decline in the egg production rate of laying hens, among which disease, stress, and nutrition are the main factors. Improving the physique of laying hens, improving immunity and disease resistance, reducing stress, and supplementing nutrition can effectively increase the egg production rate of laying hens.

[0003] Methionine is required for many reactions in animals and is also called "life amino acid". Methionine is the only sulfur-containing amino acid among essential amino acids. It is almost all used for protein synthesis in animals, and a small part is metabolized and decomposed in the body and converted into important substances related to animal development.

[0004] Lysine, which cannot be synthesized by animals, is one of the essential amino acids that livestock and poultry are most likely to lack. It is a necessary component for synthesizing nuclear proteins and hemoglobin in brain nerves, germ cells, etc. Growing animals are very sensitive to lysine deficiency. The faster the growth rate and the higher the growth intensity, the more lysine is needed. Therefore, lysine can be called a "growth amino acid". When it is deficient, livestock and poultry will stagnate in growth, and there will be phenomena such as reduced subcutaneous fat, emaciation, and abnormal bone calcification.

[0005] Cod liver oil mainly contains vitamin A and vitamin D. In addition to supplying the nutrients needed for egg production, the vitamin A in it can maintain the integrity of the epithelial cells of the body's parenchymal organs, enhance the body's resistance, and promote the body's growth and development.

[0006] Probiotics are living or dead microorganisms and their metabolites that maintain the microecological balance of the digestive tract. When consumed by livestock and poultry, probiotics can increase the number of beneficial microorganisms in the intestines and inhibit the growth of pathogenic microorganisms, thereby changing the microecological structure in the intestines, enhancing the body's immune function and achieving the purpose of promoting animal growth.

[0007] Vitamin C can improve animals' immunity and disease resistance, enhance immune effects, fight various stresses, promote bone development, increase reproduction rate, and improve eggshell quality. It has a good effect on improving animals' health and production performance.

[0008] Atractylodes macrocephala, tonifies the spleen and replenishes qi, dries dampness and promotes diuresis, stabilizes the fetus, and stops sweating. It is mainly used to treat spleen deficiency diarrhea, edema, fetal movement disorder, and spontaneous sweating. It has the effects of promoting animal growth, increasing feed intake, reducing feed-to-meat ratio, and reducing mortality. It can stimulate the growth and development of animal immune organs, activate lymphocytes, increase immunoglobulin and antibody levels, and enhance cellular immunity and humoral immunity.

[0009] Chuanxiong promotes blood circulation and qi, dispels wind and relieves pain. It has the effect of resisting vitamin E deficiency and can inhibit a variety of bacilli, and has anti-histamine and choleretic effects.

[0010] Achyranthes bidentata nourishes the liver and kidneys, strengthens tendons and bones, removes blood stasis and dredges the meridians, and guides blood downward. Adding Achyranthes bidentata to feed can improve growth performance, enhance immunity and disease resistance.

[0011] Raw Rehmannia root nourishes yin and promotes the production of body fluids, clears away heat and cools blood. It is used for fever due to yin deficiency, epistaxis, hematuria, and sore throat. Raw Rehmannia root contains rich nutrients, such as rehmannia root, mannitol, calcium, selenium, iron, vitamin A and vitamin C, which significantly promote the health of animals. Adding raw Rehmannia root to feed can enhance the immunity of animals, promote digestion and absorption, protect the liver and detoxify, relieve disease symptoms, and supplement beneficial bacteria, thereby improving the overall health of animals.

[0012] Cyperus rotundus can relieve liver depression, regulate qi and relieve fullness, and promote blood circulation and relieve pain. It is used for qi and blood stagnation, chest and abdominal distension and pain, and abdominal pain after childbirth. Cyperus rotundus can affect ovarian function. Adding Cyperus rotundus to the diet can improve the reproductive function of laying hens and increase egg production rate.

[0013] Lycium barbarum nourishes the liver and kidneys, improves the essence and improves eyesight. It is used for liver and kidney yin deficiency, weak waist and limbs, and tears in the wind. Lycium barbarum contains polysaccharides, betaine, carotene, riboflavin, vitamin C, multiple amino acids and vitamins. It can improve the production performance of animals, make the animals' coats shiny and their muscles plump. It can regulate blood lipids and blood sugar, promote the regeneration of liver cells and significantly improve kidney lesions. It can remove free radicals in the body and inhibit free radical damage to the liver. It can regulate immune function and increase the number and activity of lymphocytes and macrophages.

[0014] Pine needles contain a variety of amino acids, trace elements and vitamins, which can effectively stimulate the ovulation function of laying hens, thereby increasing the egg production rate. They also contain phytoncide, which can promote the growth of livestock and poultry, prevent gastrointestinal diseases and various vitamin deficiencies.

[0015] The above drugs are scientifically and rationally matched according to the nutritional requirements of chickens during egg laying and the need for conditioning of body functions, with the aim of enhancing the body's immunity and reproductive performance, regulating the gastrointestinal tract, increasing feed intake, and promoting growth and development. At the same time, the process of making granules after fermentation of traditional Chinese medicine not only improves the bioavailability of the drug, but also makes it easy to use, with stable quality, and uses green raw materials with no residue and no drug resistance, which is safe and effective. Summary of the invention

[0016] The present invention aims to overcome the defects of the prior art and provide a compound preparation for improving the egg production rate of laying hens. The compound preparation is scientifically and rationally matched according to the nutritional requirements of chickens during egg laying and the need for conditioning of body functions, and can enhance the body's immunity and reproductive performance, regulate the gastrointestinal tract, increase feed intake, and promote growth and development.

[0017] The second object of the present invention is to provide a method for preparing the above-mentioned compound preparation for improving the egg production rate of laying hens.

[0018] The third object of the present invention is to provide the use of the above-mentioned compound preparation in improving the egg production rate of laying hens.

[0019] To achieve the above object, the present invention adopts the following technical solution: A compound preparation for improving the egg production rate of laying hens, which is mainly made of the following raw materials in weight ratio: 6-8g of methionine, 5-10g of lysine, 3-6g of calcium hydrogen phosphate, 1-3g of cod liver oil, 4-6g of probiotics, 5-8g of vitamin C, 5-8g of Atractylodes macrocephala, 5-8g of Chuanxiong, 5-8g of Achyranthes bidentata, 5-8g of Rehmannia root, 5-8g of Cyperus rotundus, 5-8g of Lycium barbarum, 6-10g of pine needles, and 100g of culture medium; The culture medium is composed of: 3-5 g glucose, 1-3 g peptone, 0.5-1.5 g sodium chloride, 0.3-0.5 g beef extract, and purified water added to 100 g.

[0020] Specifically, the probiotics include but are not limited to one or more of bifidobacteria, lactobacilli, yeasts, etc.

[0021] As a preferred embodiment, the compound preparation for improving the egg production rate of laying hens is mainly made of the following raw materials in the following weight ratio: 6g methionine, 10g lysine, 3g calcium hydrogen phosphate, 3g cod liver oil, 4g bifidobacterium, 8g vitamin C, 5g Atractylodes macrocephala, 8g Chuanxiong, 5g Achyranthes bidentata, 8g Rehmannia root, 5g Cyperus rotundus, 8g Lycium barbarum, 6g pine needles, and 100g culture medium.

[0022] As a preferred embodiment, the compound preparation for improving the egg production rate of laying hens is mainly made of the following raw materials in weight ratio: 8g methionine, 5g lysine, 6g calcium hydrogen phosphate, 1g cod liver oil, 3g lactobacillus, 3g yeast, 5g vitamin C, 8g Atractylodes macrocephala, 5g Chuanxiong, 8g Achyranthes bidentata, 5g Rehmannia root, 8g Cyperus rotundus, 5g Lycium barbarum, 10g pine needles, and 100g culture medium.

[0023] As a preferred embodiment, the compound preparation for improving the egg production rate of laying hens is mainly made of the following raw materials in weight ratio: 7g methionine, 7.5g lysine, 4.5g calcium hydrogen phosphate, 2g cod liver oil, 3g bifidobacterium, 2g lactobacillus, 6.5g vitamin C, 6.5g Atractylodes macrocephala, 6.5g Chuanxiong, 6.5g Achyranthes bidentata, 6.5g Rehmannia root, 6.5g Cyperus rotundus, 6.5g Lycium barbarum, 8g pine needles, and 100g culture medium.

[0024] The present invention provides a method for preparing the above-mentioned compound preparation for improving the egg production rate of laying hens, which comprises the following steps: (1) Take Atractylodes macrocephala, Chuanxiong, Achyranthes bidentata, Radix Rehmanniae, Cyperus rotundus, Lycium barbarum, and pine needles, grind them into 100-200 mesh, and soak them in white wine for 12-36 hours to obtain a mixture 1; (2) Take methionine, lysine, calcium hydrogen phosphate, cod liver oil, and vitamin C, add them to mixed material 1, mix well, and obtain mixed material 2; (3) Add the probiotics to the culture medium, mix well, add to mixture 2, mix well, place in a fermentation tank and ferment at a constant temperature of 37°C ± 2°C for 60-84 hours to obtain mixture 3; (4) Add appropriate amount of sucrose and dextrin to the mixture 3 to prepare granules (the conventional technology in the art can be used, which is not the innovation of the present application and will not be described in detail), and dry to obtain granules.

[0025] Specifically, the liquor used is 42-53% liquor, and the weight ratio of the liquor to the sum of the weights of the seven Chinese medicinal materials in step (1) can be 1.2-2:1.

[0026] Specifically, during the preparation of the compound preparation, the added amounts of sucrose and dextrin are 2-3 times and 0.8-1.2 times the mass of the mixture 3, respectively.

[0027] The present invention provides a method for using the compound preparation for improving the egg production rate of laying hens, which is specifically: every 100g of the compound preparation is mixed with 50kg of feed or 100kg of drinking water, and the method can be used for a long time.

[0028] The invention also provides application of the compound preparation in improving the egg production rate of laying hens.

[0029] Compared with the prior art, the present invention has the following advantages and beneficial effects: (1) The present invention can enhance the reproductive capacity of chickens, increase the egg production rate of laying hens, improve the quality of eggs, reduce the number of broken eggs and deformed eggs, and at the same time improve the body's immunity and enhance disease resistance; (2) The present invention uses ultrafine powder of traditional Chinese medicine for fermentation, which not only increases the bioavailability of traditional Chinese medicine, but also enhances the fermentation effect. The fermented traditional Chinese medicine is converted into small molecular components, which are easier to absorb; (3) The product of the present invention is made into granules after fermentation, which increases the quality stability of the product and facilitates storage and transportation; (4) The process of the present invention is suitable for industrial production, is easily absorbed after entering the body, and is convenient for clinical administration, suitable for group administration, and saves manpower and material resources; (5) The drug content of the present invention is clear, the dosage is accurate, and the quality is controllable. DETAILED DESCRIPTION

[0030] The technical solution of the present invention is further described in detail below in conjunction with the embodiments, but the protection scope of the present invention is not limited thereto.

[0031] In the following examples, the raw materials used are all common commercial products that can be directly purchased or prepared by conventional methods in the art. For example, Bifidobacterium (viable count ≥ 10 billion CFU / g) was purchased from Shandong Pingju Biotechnology Co., Ltd., Lactobacillus (viable count ≥ 10 billion CFU / g) was purchased from Shandong Pingju Biotechnology Co., Ltd., and yeast (viable count ≥ 10 billion CFU / g) was purchased from Zhejiang Yicun Biotechnology Co., Ltd.

[0032] Example 1 Compound preparation for improving egg production rate of laying hens The compound preparation for improving the egg production rate of laying hens has the following components and weight ratios: Methionine 6g, lysine 10g, calcium hydrogen phosphate 3g, cod liver oil 3g, bifidobacterium 4g, vitamin C 8g, Atractylodes macrocephala 5g, Ligusticum chuanxiong 8g, Achyranthes bidentata 5g, Rehmannia root 8g, Cyperus rotundus 5g, Lycium barbarum 8g, pine needle 6g, and culture medium 100g; Culture medium components: 3 g glucose, 3 g peptone, 0.5 g sodium chloride, 0.5 g beef extract, and purified water added to 100 g.

[0033] The preparation method of the compound preparation for improving the egg production rate of laying hens comprises the following steps: (1) Grind Atractylodes macrocephala, Ligusticum chuanxiong, Achyranthes bidentata, Radix Rehmanniae, Cyperus rotundus, Lycium barbarum, and pine needles into 150 meshes, and soak them in liquor at room temperature for 24 hours to obtain a mixture 1; (2) Take methionine, lysine, calcium hydrogen phosphate, cod liver oil, and vitamin C, add them to mixed material 1, mix well, and obtain mixed material 2; (3) Add bifidobacterium to the culture medium, mix well, add to mixture 2, mix well, place in a fermentation tank, and ferment at a constant temperature of 37°C ± 2°C for 72 hours to obtain mixture 3; (4) Add appropriate amounts of sucrose and dextrin to the mixture 3 to form granules, and dry them to obtain the product of the present invention.

[0034] In the present method: (1) the liquor used has a concentration of 53% alcohol, and the weight ratio of the liquor to the sum of the weights of the seven Chinese medicinal materials in step (1) is 1.5:1.

[0035] (2) The mass ratio of sucrose: dextrin: mixture 3 is 3:1:1.

[0036] Example 2 Compound preparation for improving egg production rate of laying hens The compound preparation for improving the egg production rate of laying hens has the following components and weight ratios: Methionine 8g, lysine 5g, calcium hydrogen phosphate 6g, cod liver oil 1g, lactobacillus 3g, yeast 3g, vitamin C 5g, Atractylodes macrocephala 8g, Ligusticum chuanxiong 5g, Achyranthes bidentata 8g, Rehmannia root 5g, Cyperus rotundus 8g, Lycium barbarum 5g, pine needle 10g, and culture medium 100g; Culture medium components: 5 g glucose, 1 g peptone, 1.5 g sodium chloride, 0.3 g beef extract, and purified water added to 100 g.

[0037] The preparation method of the compound preparation for improving the egg production rate of laying hens comprises the following steps: (1) Grind Atractylodes macrocephala, Ligusticum chuanxiong, Achyranthes bidentata, Radix Rehmanniae, Cyperus rotundus, Lycium barbarum, and pine needles into 150 meshes, and soak them in liquor at room temperature for 24 hours to obtain a mixture 1; (2) Take methionine, lysine, calcium hydrogen phosphate, cod liver oil, and vitamin C, add them to mixed material 1, mix well, and obtain mixed material 2; (3) Add lactobacillus and yeast to the culture medium, mix well, add to mixture 2, mix well, place in a fermentation tank, and ferment at a constant temperature of 37°C ± 2°C for 72 hours to obtain mixture 3; (4) Add appropriate amounts of sucrose and dextrin to the mixture 3 to form granules, and dry them to obtain the product of the present invention.

[0038] In the present method: (1) the liquor used has a concentration of 53% alcohol, and the weight ratio of the liquor to the sum of the weights of the seven Chinese medicinal materials in step (1) is 1.5:1.

[0039] (2) The mass ratio of sucrose: dextrin: mixture 3 is 3:1:1.

[0040] Example 3 Compound preparation for improving egg production rate of laying hens The compound preparation for improving the egg production rate of laying hens has the following components and weight ratios: 7g methionine, 7.5g lysine, 4.5g calcium hydrogen phosphate, 2g cod liver oil, 3g bifidobacterium, 2g lactobacillus, 6.5g vitamin C, 6.5g atractylodes, 6.5g ligusticum, 6.5g cyperus, 6.5g achyranthes, 6.5g raw rehmannia, 6.5g cyperus, 6.5g wolfberry, 8g pine needles, and 100g culture medium; Culture medium components: 4 g glucose, 2 g peptone, 1 g sodium chloride, 0.4 g beef extract, and purified water added to 100 g.

[0041] The preparation method of the compound preparation for improving the egg production rate of laying hens comprises the following steps: (1) Grind Atractylodes macrocephala, Ligusticum chuanxiong, Achyranthes bidentata, Radix Rehmanniae, Cyperus rotundus, Lycium barbarum, and pine needles into 150 meshes, and soak them in liquor at room temperature for 24 hours to obtain a mixture 1; (2) Take methionine, lysine, calcium hydrogen phosphate, cod liver oil, and vitamin C, add them to mixed material 1, mix well, and obtain mixed material 2; (3) Bifidobacterium and lactobacillus are added to the culture medium, mixed evenly, and then added to the mixture 2, mixed evenly, placed in a fermentation tank, and fermented at a constant temperature of 37°C ± 2°C for 72 hours to obtain a mixture 3; (4) Add appropriate amounts of sucrose and dextrin to the mixture 3 to form granules, and dry them to obtain the product of the present invention.

[0042] In the present method: (1) the liquor used has a concentration of 53% alcohol, and the weight ratio of the liquor to the sum of the weights of the seven Chinese medicinal materials in step (1) is 1.5:1.

[0043] (2) The mass ratio of sucrose: dextrin: mixture 3 is 3:1:1.

[0044] Comparative Example 1 Preparation of a reference substance for a compound preparation for improving egg production rate of laying hens The reference substance of the compound preparation for improving the egg production rate of laying hens has the following components and weight ratios: 7g methionine, 7.5g lysine, 4.5g calcium hydrogen phosphate, 2g cod liver oil, 3g bifidobacterium, 2g lactobacillus, 6.5g vitamin C, 6.5g atractylodes, 6.5g ligusticum, 6.5g cyperus, 6.5g achyranthes, 6.5g raw rehmannia, 6.5g cyperus, 6.5g wolfberry, 8g pine needles, and 100g culture medium; Culture medium components: 4 g glucose, 2 g peptone, 1 g sodium chloride, 0.4 g beef extract, and purified water added to 100 g.

[0045] The preparation method of the reference substance of the compound preparation for improving the egg production rate of laying hens comprises the following steps: (1) Grind Atractylodes macrocephala, Ligusticum chuanxiong, Achyranthes bidentata, Radix Rehmanniae, Cyperus rotundus, Lycium barbarum, and pine needles into 150 meshes, and soak them in liquor at room temperature for 24 hours to obtain a mixture 1; (2) Bifidobacterium and lactobacillus are added to the culture medium, mixed evenly, and then added to the mixture 1, mixed evenly, placed in a fermentation tank, and fermented at a constant temperature of 37°C ± 2°C for 72 hours to obtain a mixture 2; (3) Take methionine, lysine, calcium hydrogen phosphate, cod liver oil, and vitamin C, add them to mixture 2, mix well, and obtain mixture 3; (4) Add appropriate amounts of sucrose and dextrin to the mixture 3 to form granules, and dry them to obtain the product of the present invention.

[0046] In the present method: (1) the liquor used has a concentration of 53% alcohol, and the weight ratio of the liquor to the sum of the weights of the seven Chinese medicinal materials in step (1) is 1.5:1.

[0047] Note: In this method, methionine, lysine, calcium hydrogen phosphate, cod liver oil, and vitamin C do not participate in the fermentation process.

[0048] (2) The mass ratio of sucrose: dextrin: mixture 3 is 3:1:1.

[0049] Comparative Example 2 Preparation of a reference substance for a compound preparation for improving egg production rate of laying hens The reference substance of the compound preparation for improving the egg production rate of laying hens has the following components and weight ratios: 7g methionine, 7.5g lysine, 4.5g calcium hydrogen phosphate, 2g cod liver oil, 3g bifidobacterium, 2g lactobacillus, 6.5g vitamin C, 6.5g atractylodes, 6.5g ligusticum, 6.5g cyperus, 6.5g achyranthes, 6.5g raw rehmannia, 6.5g cyperus, 6.5g wolfberry, 8g pine needles, and 100g culture medium; Culture medium components: 4 g glucose, 2 g peptone, 1 g sodium chloride, 0.4 g beef extract, and purified water added to 100 g.

[0050] The preparation method of the reference substance of the compound preparation for improving the egg production rate of laying hens comprises the following steps: (1) Grind Atractylodes macrocephala, Ligusticum chuanxiong, Achyranthes bidentata, Radix Rehmanniae, Cyperus rotundus, Lycium barbarum, and pine needles into 150 meshes, and soak them in liquor at room temperature for 24 hours to obtain a mixture 1; (2) Take methionine, lysine, calcium hydrogen phosphate, cod liver oil, and vitamin C, add them to mixed material 1, mix well, and obtain mixed material 2; (3) Take bifidobacterium and lactobacillus and add them to the culture medium, mix them evenly, then add them to mixed material 2, mix them evenly, place them in a fermentation tank, ferment them at a constant temperature of 37°C±2°C for 72 hours, take them out, dry them, and crush them to obtain the product.

[0051] In the present method: (1) the liquor used has a concentration of 53% alcohol, and the weight ratio of the liquor to the sum of the weights of the seven Chinese medicinal materials in step (1) is 1.5:1.

[0052] Note: This method does not produce pellets.

[0053] Comparative Example 3 Preparation of a reference substance for a compound preparation for improving egg production rate of laying hens The reference substance of the compound preparation for improving the egg production rate of laying hens has the following components and weight ratios: Methionine 7g, lysine 7.5g, calcium hydrogen phosphate 4.5g, cod liver oil 2g, vitamin C 6.5g, Atractylodes macrocephala 6.5g, Ligusticum chuanxiong 6.5g, Achyranthes bidentata 6.5g, Rehmannia root 6.5g, Cyperus rotundus 6.5g, Lycium barbarum 6.5g, pine needle 8g, and purified water 100g.

[0054] The preparation method of the reference substance of the compound preparation for improving the egg production rate of laying hens comprises the following steps: (1) Grind Atractylodes macrocephala, Ligusticum chuanxiong, Achyranthes bidentata, Radix Rehmanniae, Cyperus rotundus, Lycium barbarum, and pine needles into 150 meshes, and soak them in liquor at room temperature for 24 hours to obtain a mixture 1; (2) Take methionine, lysine, calcium hydrogen phosphate, cod liver oil, and vitamin C, add purified water to dissolve, and obtain a mixture 2 for later use; (3) Add mixed material 2 to mixed material 1, mix well, add appropriate amount of sucrose and dextrin to make a soft material, pass through a 16-mesh sieve to make granules, and dry to obtain the product of the present invention.

[0055] Note: This method does not contain probiotics, culture medium and fermentation process.

[0056] Application test, comparative test of the effect of the preparation of the present invention on the egg production rate of laying hens Proceed as follows: 1. Drugs and reagents Test groups 1, 2, and 3: the compound preparations prepared in Examples 1, 2, and 3 were added respectively; Control groups 1, 2, and 3: the compound preparations prepared in comparative examples 1, 2, and 3 were added respectively; Blank control group: no drug was added.

[0057] (II) Test methods (1) Experimental design: 7,000 healthy laying hens with basically uniform body weight were selected from 15,000 laying hens in the same chicken house and divided into 7 groups, with 4 replicates in each group and 250 hens in each replicate. After grouping, the egg production rates of the 6 groups were analyzed by biostatistics, and there was no significant difference (P>0.05). The experimental period was 48 days.

[0058] The diet of the test group was the basic diet + 0.2% of the compound preparation prepared in the embodiment, the diet of the control group was the basic diet + 0.2% of the compound preparation prepared in the comparative example, and the blank control group was the basic diet.

[0059] (2) Measurement indicators: egg production rate, average egg weight, egg production, feed-egg ratio, feed consumption, and number of dead and culled chickens.

[0060] (3) The test results are shown in Table 1.

[0061] Table 1 Production performance of laying hens As can be seen from Table 1, the average egg production rate of the experimental group was 91.32%, which was 2.5%, 3.1%, 4.2% and 5.0% higher than that of the control groups 1, 2, 3 and the blank control group respectively; the feed-to-egg ratio of the experimental group was 1.95 on average, which was 0.03, 0.07, 0.20 and 0.36 lower than that of the control groups 1, 2, 3 and the blank control group respectively; the average total egg weight of the experimental group was 2664, which was 4.7%, 5.1%, 8.5% and 11.4% higher than that of the control groups 1, 2, 3 and the blank control group respectively; the number of dead chickens in the experimental group was 6 on average, which was 4, 5, 12 and 18 fewer than that of the control groups 1, 2, 3 and the blank control group respectively.

[0062] From the above data analysis, it can be seen that the process method of making granules after fermentation of traditional Chinese medicine adopted in the present invention can significantly improve the effect of the product, and the participation of amino acids, vitamins and trace elements in the fermentation process also has a certain influence on the product effect.

Claims

1. A compound preparation for improving the egg production rate of laying hens, characterized in that: It is mainly made of the following raw materials in weight ratio: 6-8g of methionine, 5-10g of lysine, 3-6g of calcium hydrogen phosphate, 1-3g of cod liver oil, 4-6g of probiotics, 5-8g of vitamin C, 5-8g of Atractylodes macrocephala, 5-8g of Chuanxiong, 5-8g of Achyranthes bidentata, 5-8g of Rehmannia root, 5-8g of Cyperus rotundus, 5-8g of Lycium barbarum, 6-10g of pine needles, and 100g of culture medium; The culture medium is composed of: 3-5 g glucose, 1-3 g peptone, 0.5-1.5 g sodium chloride, 0.3-0.5 g beef extract, and purified water added to 100 g.

2. The compound preparation for improving the egg production rate of laying hens as claimed in claim 1, characterized in that: The probiotics are one or more of bifidobacteria, lactobacilli and yeast.

3. The compound preparation for improving the egg production rate of laying hens as claimed in claim 2, characterized in that: The invention is mainly prepared from the following raw materials in weight proportion: 6g of methionine, 10g of lysine, 3g of calcium hydrogen phosphate, 3g of cod liver oil, 4g of bifidobacterium, 8g of vitamin C, 5g of atractylodes macrocephala, 8g of ligusticum chuanxiong, 5g of achyranthes bidentata, 8g of raw rehmannia root, 5g of cyperus rotundus, 8g of wolfberry, 6g of pine needle and 100g of culture medium.

4. The compound preparation for improving the egg production rate of laying hens as claimed in claim 2, characterized in that: The invention is mainly prepared from the following raw materials in weight proportion: 8g of methionine, 5g of lysine, 6g of calcium hydrogen phosphate, 1g of cod liver oil, 3g of lactobacillus, 3g of yeast, 5g of vitamin C, 8g of atractylodes macrocephala, 5g of ligusticum chuanxiong, 8g of achyranthes bidentata, 5g of raw rehmannia root, 8g of cyperus rotundus, 5g of wolfberry, 10g of pine needle and 100g of culture medium.

5. The compound preparation for improving the egg production rate of laying hens as claimed in claim 2, characterized in that: The invention is mainly prepared from the following raw materials in the following weight ratio: 7g methionine, 7.5g lysine, 4.5g calcium hydrogen phosphate, 2g cod liver oil, 3g bifidobacterium, 2g lactobacillus, 6.5g vitamin C, 6.5g atractylodes, 6.5g ligusticum, 6.5g achyranthes, 6.5g rehmannia root, 6.5g cyperus, 6.5g wolfberry, 8g pine needle and 100g culture medium.

6. The method for preparing the compound preparation for improving the egg production rate of laying hens according to any one of claims 1 to 5, characterized in that: The steps include: (1) Take Atractylodes macrocephala, Chuanxiong, Achyranthes bidentata, Radix Rehmanniae, Cyperus rotundus, Lycium barbarum, and pine needles, grind them, and soak them in white wine to obtain a mixture 1; (2) Take methionine, lysine, calcium hydrogen phosphate, cod liver oil, and vitamin C, add them to mixed material 1, mix well, and obtain mixed material 2; (3) Add the probiotics to the culture medium, mix well, add to mixture 2, mix well, and ferment at a constant temperature of 37°C ± 2°C for 60-84 hours to obtain mixture 3; (4) Add appropriate amount of sucrose and dextrin to the mixture 3 to make granules, and dry them to obtain granules.

7. The method for preparing the compound preparation for improving the egg production rate of laying hens as claimed in claim 6, characterized in that: The liquor used is 42-53% liquor, and the weight ratio of the liquor to the sum of the weights of the seven Chinese medicinal materials in step (1) is 1.2-2:

1.

8. The method for preparing the compound preparation for improving the egg production rate of laying hens as claimed in claim 6, characterized in that: The added amounts of sucrose and dextrin are 2-3 times and 0.8-1.2 times the mass of mixture 3 respectively.

9. The method for using the compound preparation for improving the egg production rate of laying hens according to any one of claims 1 to 5, characterized in that: For every 100g of compound preparation, mix with 50kg of feed or 100kg of drinking water.

10. Use of the compound preparation according to any one of claims 1 to 5 in improving the egg production rate of laying hens.