Three-flower tea as well as preparation method and application thereof
By developing Sanhua tea, mint, rose, chrysanthemum and tarttoe flowers are mixed and ground in a specific proportion, as a tea that is both medicinal and food-related, it solves the modern people's needs for convenient and efficient Chinese medicine treatment and achieves liver relief The effect of calming qi, relieving worries and relieves depression improves compliance with medication.
Patent Information
- Application Number
- CN202411674196.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-21
- Publication Date
- 2025-02-18
AI Technical Summary
The existing Chinese medicine treatment methods for depression need to be treated according to the specific symptoms of the patient. Modern people have high life pressure and a high incidence of emotional discomfort. Traditional Chinese medicine is relatively low in compliance, which is difficult to meet the growing convenience of modern people. and efficient medical needs.
Develop a three-flower tea, which is made by mixing and grinding mint, rose, chrysanthemum and tarttoe flowers in a specific proportion, and serve as a tea that is both medicinal and food-related, so as to achieve the effect of relieving liver and qi and improving medication compliance.
Through the synergistic effect of its ingredients, Sanhua tea significantly regulates qi and relieves liver, relieves worries and relieves depression, and has good effect on treating depression. It is also cheap and has no toxic side effects, which improves bioavailability and reduces the dosage of native medicinal materials.
Smart Images

Figure CN119454808A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of Chinese medicinal tea substitutes, and in particular to three-flower tea and a preparation method and application thereof. Background Art
[0002] Depression is a disease in traditional Chinese medicine, which is mainly caused by emotional discomfort and stagnation of qi. Clinical manifestations include depression, restlessness, chest fullness, chest and flank pain, irritability and crying, or foreign body obstruction in the throat. Its causes involve liver failure to release, spleen failure to function properly, heart failure to nourish, and imbalance of yin and yang, qi and blood in the internal organs. The disease is mainly located in the liver, but it may also involve internal organs such as the heart, spleen, and kidney. At the beginning of depression, the lesions are mainly qi stagnation, often accompanied by blood stasis, fire transformation, phlegm accumulation, food stagnation and other symptoms. However, as the disease progresses, depression may turn from real to virtual, forming deficiency lesions of internal organs such as the heart, spleen, liver, and kidney. TCM treatment methods include syndrome differentiation and treatment, Chinese medicine conditioning, and special mood regulation. When treating depression with Chinese medicine, syndrome differentiation and treatment will be carried out according to the patient's specific symptoms.
[0003] For example, the liver qi stagnation type: it is often manifested as depression, sighing, and sometimes accompanied by pain in the ribs. During treatment, Chaihu Shugan San is often used to relieve liver qi and relieve depression. Qi stagnation and fire type: patients are impatient and irritable, and may also feel chest tightness, pain in the ribs, dry and bitter mouth, etc. During treatment, Danzhi Xiaoyao San or Longdan Xiegan Tang are often used to clear liver and purge fire, relieve depression and relieve liver. Qi stagnation and phlegm obstruction type: it is manifested as if there is a foreign body blocking the throat, which cannot be coughed out or swallowed, and chest tightness. During treatment, Banxia Houpu Tang is often used to resolve phlegm, promote qi and relieve depression. For the heart and spleen deficiency type, Guipi Tang is often used to strengthen the spleen and nourish the heart, replenish qi and blood; for the liver and kidney deficiency type, Erxian Tang is often used to balance and nourish the liver and kidney and harmonize yin and yang.
[0004] However, it should be noted that Chinese medicine treatment needs to comprehensively consider the patient's constitution, condition and other factors. Therefore, the specific medication and dosage should be determined by the doctor according to the patient's specific situation. At the same time, when taking Chinese medicine, patients should also follow the doctor's instructions and pay attention to the method and precautions of taking the medicine. Taking into account the work pace and life pressure of modern people, the high incidence of emotional distress, combined with the actual compliance of taking Chinese medicine. Further exploration based on syndrome differentiation and treatment, digging out suitable medicine and food homology, comfortable medicinal taste substitutes, clarifying their preparation process, more convenient for contemporary people's taking habits, and effectively improving medication compliance is of great significance. Summary of the invention
[0005] The present invention aims to provide a three-flower tea and a preparation method and application thereof, aiming to achieve the effect of soothing the liver and relieving qi by using a tea substitute that is both medicinal and edible, while improving medication compliance.
[0006] To achieve the above purpose, the present invention adopts the following technical scheme: a three-flower tea, which includes the following raw materials, by weight, 10 to 20 parts of mint, 10 to 20 parts of roses, 5 to 15 parts of chrysanthemums, and 10 to 20 parts of chrysanthemums.
[0007] Preferably, as an improvement, the mass parts of each raw material are: 10-15 parts of mint, 10-15 parts of roses, 10-15 parts of chrysanthemums, and 10-15 parts of chrysanthemums.
[0008] Preferably, as an improvement, the mass parts of each raw material are: 10 parts of mint, 10 parts of rose, 5 parts of chrysanthemum, and 10 parts of chrysanthemum.
[0009] Preferably, as an improvement, the mass parts of each raw material are: 20 parts of mint, 20 parts of rose, 15 parts of chrysanthemum, and 10 parts of chrysanthemum.
[0010] Preferably, as an improvement, a method for preparing three-flower tea comprises the following steps:
[0011] Step 1: Material selection: Choose authentic medicinal materials such as mint, rose, chrysanthemum, and chrysanthemum;
[0012] Step 2: Cleaning and drying: Wash with water and then dry;
[0013] Step 3: Mix and grind: Mix and grind according to the proportion to get Sanhua Tea.
[0014] Preferably, as an improvement, in step 2, the drying temperature is 30-45° C., and the drying time is 1-2.
[0015] Preferably, as an improvement, in step three, the particle size after grinding is 1 to 5 mm.
[0016] Preferably, as an improvement, a three-flower tea is used in the preparation of a liver-soothing and qi-regulating medicine.
[0017] The principle and advantage of this scheme are: in actual application, in this technical scheme, mint (Mentha haplocalyx) has the effect of soothing the liver and relieving depression, and can relieve the discomfort symptoms caused by liver qi stagnation. Rose (Rosa rugosa) has the effect of soothing the liver and relieving depression, and can help relieve liver qi stagnation caused by bad mood. The aromatic components in rose help relieve depression and improve mood. Chrysanthemum (Chrysanthemumindicum) has the effect of clearing heat and detoxifying, and can help relieve various symptoms caused by heat toxins. Citrus aurantium var.amara has the effect of regulating qi and widening the chest, and can help relieve symptoms such as chest tightness and chest pain caused by qi stagnation. In addition, the volatile oil components in Citrus aurantium have a certain calming effect, which can help improve sleep quality. The above-mentioned medicinal materials are combined into a Chinese medicine substitute tea, which has a significant effect of regulating qi and soothing the liver, relieving worries and relieving depression, and has a good effect on treating depression, and is low in cost and has no toxic side effects. At the same time, the preparation method adopted by the present invention can extract and utilize the effective active ingredients of each medicine to the maximum extent, maximize the efficacy of each medicine and the efficacy of health products, improve their bioavailability, and correspondingly reduce the amount of original medicinal materials.
[0018] In summary, the beneficial effects of this technical solution are:
[0019] 1. In terms of material selection, this technical solution strictly selects authentic medicinal materials, strictly controls different types of flowers, and selects appropriate temperature-controlled boxes to dry the various components in the scented tea, overcoming the technical difficulties of properties and bioavailability between different components. In the process of scented tea production, it overcomes the technical obstacles of scented tea fragrance, and uses special packaging materials to retain the aroma components in the scented tea.
[0020] 2. In this technical solution, mint and rose have obvious synergistic and strong effects. Mint is pungent, cool in nature, and enters the lung and liver meridians, and has the effect of soothing the liver and promoting qi. Rose tastes dry and slightly bitter, is warm in nature, and enters the liver and spleen meridians, and has the effect of promoting qi and relieving depression. The two are warm and cool, and they synergistically enhance the effect of promoting qi and soothing the liver.
[0021] 3. In the present technical solution, the raw material used is the uncommon hawksbill flower, which is the dried flower bud of the rutaceae plant hawksbill flower, also known as citron flower. It is sweet, slightly bitter, neutral in nature, and enters the liver and stomach meridians. It has the effects of regulating qi, widening the chest, appetizing and stopping vomiting. The dried mature fruits of rutaceae plants such as citron and bergamot are commonly used in this field. Hawksbill flower has the advantages of light weight and easy precipitation of effective ingredients. Its effect of regulating qi is not inferior to that of citron and bergamot of the same type of plants, and its volatile oil components have a certain calming effect.
[0022] 4. Compared with traditional prescriptions for soothing the liver and regulating qi, such as Xiaoyao Powder, this plan eliminates herbs such as Bupleurum and Angelica. Herbs such as Bupleurum and Angelica are bitter, so this plan eliminates bitter herbs from traditional prescriptions for soothing the liver and regulating qi, which is more conducive to the acceptance of the beneficiary groups. In addition, the herbs selected in this plan have the advantage of being aromatic. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] Figure 1 The present invention is a process flow chart of preparing the third flower tea. DETAILED DESCRIPTION
[0024] The following is further described in detail through specific implementations, but the implementation of the present invention is not limited thereto. Unless otherwise specified, the technical means used in the following implementations are conventional means well known to those skilled in the art; the experimental methods used are all conventional methods; the materials, reagents, etc. used can all be obtained from commercial channels.
[0025] Program Overview:
[0026] like Figure 1 As shown: A three-flower tea, calculated by mass, includes the following raw materials: 10 to 20 parts of mint, 10 to 20 parts of roses, 5 to 15 parts of chrysanthemums, and 10 to 20 parts of chrysanthemums.
[0027] A method for preparing three-flower tea comprises the following steps:
[0028] Step 1: Material selection and preparation: Select authentic medicinal materials such as mint, rose, chrysanthemum, and chrysanthemum;
[0029] Step 2: Cleaning and drying: Clean the selected Chinese herbal medicines to remove dust and impurities on the surface. When cleaning, rinse gently with running water, and be careful not to rub hard to avoid damaging the structure of the herbs. After cleaning, dry the herbs in the air or wipe them with clean gauze. Then, put the herbs in an oven or a dry and ventilated place to dry them to remove excess moisture and prevent them from getting moldy and deteriorating.
[0030] Step 3: Grinding and mixing: sort the dried herbs, mix and grind them according to the proportion, and the particle size of the herbs after grinding is 1-5mm. When mixing, you can adjust according to your personal taste and physical characteristics to achieve the best effect.
[0031] Example 1
[0032] A three-flower tea comprises the following raw materials: 10g of mint, 10g of rose, 5g of chrysanthemum and 10g of iris.
[0033] A method for preparing three-flower tea comprises the following steps:
[0034] Step 1: Material selection and preparation: select 10g mint, 10g rose, 5g chrysanthemum, and 10g chrysanthemum;
[0035] Step 2: Cleaning and drying: Clean the selected Chinese herbal medicines to remove dust and impurities on the surface. When cleaning, rinse gently with running water, and be careful not to rub hard to avoid damaging the structure of the herbs. After cleaning, dry the herbs in the air or wipe them with clean gauze. Then, put the herbs in an oven or a dry and ventilated place to dry them to remove excess moisture and prevent them from getting moldy and deteriorating.
[0036] Step 3: Grinding and mixing: sort the dried herbs, mix and grind them according to the proportion, and the particle size of the herbs after grinding is 1-5mm. When mixing, you can adjust according to your personal taste and physical characteristics to achieve the best effect.
[0037] Example 2
[0038] A three-flower tea comprises the following raw materials: 20g of mint, 20g of rose, 15g of chrysanthemum and 20g of chrysanthemum.
[0039] A method for preparing three-flower tea comprises the following steps:
[0040] Step 1: Material selection and preparation: select 20g mint, 20g rose, 15g chrysanthemum, and 20g chrysanthemum;
[0041] Step 2: Cleaning and drying: Clean the selected Chinese herbal medicines to remove dust and impurities on the surface. When cleaning, rinse gently with running water, and be careful not to rub hard to avoid damaging the structure of the herbs. After cleaning, dry the herbs in the air or wipe them with clean gauze. Then, put the herbs in an oven or a dry and ventilated place to dry them to remove excess moisture and prevent them from getting moldy and deteriorating.
[0042] Step 3: Grinding and mixing: sort the dried herbs, mix and grind them according to the proportion, and the particle size of the herbs after grinding is 1-5mm. When mixing, you can adjust according to your personal taste and physical characteristics to achieve the best effect.
[0043] Example 3
[0044] A three-flower tea comprises the following raw materials: 10g of mint, 20g of rose, 10g of chrysanthemum and 10g of iris.
[0045] A method for preparing three-flower tea comprises the following steps:
[0046] Step 1: Material selection and preparation: select 10g mint, 20g rose, 10g chrysanthemum, and 10g chrysanthemum;
[0047] Step 2: Cleaning and drying: Clean the selected Chinese herbal medicines to remove dust and impurities on the surface. When cleaning, rinse gently with running water, and be careful not to rub hard to avoid damaging the structure of the herbs. After cleaning, dry the herbs in the air or wipe them with clean gauze. Then, put the herbs in an oven or a dry and ventilated place to dry them to remove excess moisture and prevent them from getting moldy and deteriorating.
[0048] Step 3: Grinding and mixing: sort the dried herbs, mix and grind them according to the proportion, and the particle size of the herbs after grinding is 1-5mm. When mixing, you can adjust according to your personal taste and physical characteristics to achieve the best effect.
[0049] Experimental Example 1 Safety Toxicology Study
[0050] 1 Experimental Materials
[0051] 1.1 Main instruments, equipment and reagents
[0052] Dissecting instruments, electronic balances, refrigerators, centrifuges, etc. are commonly used in laboratories.
[0053] Reagent: 0.1% colchicine, in a brown bottle, stored in the refrigerator.
[0054] 1% trisodium citrate: take 1g trisodium citrate (analytical grade) and add distilled water to make up to 100mL.
[0055] 60% glacial acetic acid: Take 60 mL of glacial acetic acid (analytical grade) and add distilled water to 100 mL.
[0056] Fixative: V methanol: V glacial acetic acid = 3:1, prepare before use.
[0057] Phosphate buffer (pH 7.4): Disodium hydrogen phosphate (NaHPO, analytical grade) 9.47 g was dissolved in 1 000 mL of distilled water to prepare disodium hydrogen phosphate solution (1 / 15 mol / ): Disodium dihydrogen phosphate (KHPO, analytical grade) 9.07 g was dissolved in 1 000 mL of distilled water to prepare potassium dihydrogen phosphate solution (1 / 15 mol / ). Mix 80 mL of disodium hydrogen phosphate solution (1 / 15 mol / L) with 20 mL of potassium dihydrogen phosphate solution (1 / 15 mol / L) and adjust the pH to 7.4.
[0058] Giemsa dye solution: Weigh 3.8g of Giemsa dye solution, add 375mL methanol (analytical grade) and grind. After it is completely dissolved, add 125mL glycerol. Keep it in a 37℃ thermostat for 48h and shake it several times. Filter it and use it after two weeks.
[0059] Giemsa application solution: Mix 1 part of Giemsa stain with 9 parts of phosphate buffer and prepare it before use.
[0060] 1.2 Preparation of experimental materials
[0061] 1.2.1 Preparation of Sanhua Tea
[0062] Select authentic medicinal materials such as mint, rose, chrysanthemum and aster; wash and dry: wash with water and then dry (temperature is 30-45°C); mix and grind: mix according to proportion and then grind to obtain three-flower tea (particle size after grinding is 1-5 mm).
[0063] 1.2.2 Acute toxicity test sample processing
[0064] Weigh 15g of Sanhua tea sample into a beaker, add 150mL of pure water, soak at 80℃ for 30min, then pour out the soaking liquid; add another 150mL of pure water, soak at 80℃ for 30min, then pour out the soaking liquid. Combine the two soaking liquids, heat and concentrate to 20mL, pour into a reagent bottle, mark and set aside.
[0065] 1.2.3 Sample processing for mouse sperm abnormality experiment
[0066] Weigh 30g of the three-flower tea sample into a beaker, add 150mL of pure water, soak at 80℃ for 30min, and pour out the soaking liquid; add another 150ml of pure water, soak at 80℃ for 30min, and pour out the soaking liquid. Combine the two soaking liquids, heat and concentrate to 60mL, as the highest dose of 10,000mg / kg. Take 15mL of the highest dose solution and dilute it by one-fold to 5,000mg / kg. Take 5mL of the highest dose solution and dilute it ten-fold to 1,000mg / kg.[3]1.2.4 Experimental Animals
[0067] Clean-grade ICR mice were provided by Zhejiang Experimental Animal Center, with the license number SCXK(Zhejiang)2014-0001. A total of 20 mice were used for the acute oral toxicity test, including 10 males and 10 females. A total of 25 male mice were used for the mouse spermatogonial abnormality test.
[0068] Animals in each test group were housed in separate cages according to gender. Animals in each cage were allowed to move freely; a relaxed environment was maintained to facilitate observation. During the test, experimental animals were fed with basic feed and free drinking water was guaranteed. Before the test, experimental animals were required to undergo 3 days of environmental adaptation and quarantine observation in the test environment. They were fasted for 4 hours before the test, but free drinking water was allowed.
[0069] Select healthy adult mice (18-22 g) of both sexes. Female animals should be virgin and non-pregnant. The weight difference between individual experimental animals of the same sex should not exceed ±20% of the average weight.
[0070] Experimental methods
[0071] 2.1 Acute toxicity test method
[0072] Administration route: oral administration,
[0073] The maximum tolerated dose method was used, and the oral dose was 15,000 mg / kg; the animals were fasted for 16 hours before exposure. After exposure, the poisoning symptoms or behavioral changes were observed every day, and the animals were weighed once a week. The animals that died of poisoning and the animals that survived 14 days after exposure were dissected and observed.
[0074] 2.2 Experimental methods of mouse sperm abnormality
[0075] 2.2.1 Contamination and testing
[0076] The animals in each group were exposed to the drug for 5 consecutive days. The mice were killed by cervical dislocation on the 30th day after the last administration of the test substance. The epididymis was taken to make saline suspension smears, 5 pieces per group, dried naturally, fixed with methanol for 7 minutes, dried, stained with eosin, and examined under a microscope.
[0077] 2.2.2 Control group
[0078] Purified water was used as the negative control group. Except for not using the test sample, other treatments were the same as those of the test substance group.
[0079] The positive control was cyclophosphamide (40 mg / kg body weight, single intraperitoneal injection).
[0080] 2.2.3 Dosage
[0081] The test substance was divided into three dosage groups: 1000, 5000, and 10000 mg / kg.
[0082] 2.3 Experimental Environment
[0083] Barrier environment animal room, use license number: SYXK (Zhejiang) 2016-0012, room temperature 21.5 ~ 25.0 ℃; relative humidity 52.0% ~ 65.0%.
[0084] 3 Results and Analysis
[0085] 3.1 Acute toxicity test
[0086] All experimental animals showed ataxia symptoms 4 hours after exposure to the poison. After 24 hours, the symptoms disappeared and the animals returned to normal. No poisoning deaths were found within 14 days. The weight of male and female animals was normal. After the experimental observation, the animals were dissected and observed, and no abnormalities were found. The oral gavage experiment on mice with the sample showed that the LD50 was > 15,000 mg / kg. According to the acute toxicity classification, the sample belongs to the oral non-toxic level, see Table 1.
[0087] Table 1 Results of acute oral toxicity test of three-flower tea
[0088]
[0089] 3.2 Mouse sperm abnormality experiment
[0090] The experimental results (Table 2) showed that compared with the negative control group, the positive control group treated with 40 mg / kg cyclophosphamide caused a significant increase in the number of abnormal sperm in mice, while there was no significant difference in the number of abnormal sperm in mice in each drug-treated group compared with the negative control group.
[0091] The test substance was divided into three dosage groups: 1000, 5000, and 10000 mg / kg. Compared with the negative control group, there was no significant difference in the sperm deformity rate. The sperm deformity rate of the test substance in mice was within the normal deformity range, and no genetic toxicity of the test substance to mouse male germ cells was observed.
[0092] Table 2 Results of the experiment on sperm abnormality caused by three-flower tea in mice
[0093]
[0094]
[0095] Note: The positive control is cyclophosphamide, 40 mg / kg; the negative control is purified water.
[0096] Experimental Example 2
[0097] The therapeutic effect of "Sanhua Tea", a traditional Chinese medicine tea substitute for soothing the liver and regulating qi, and regulating qi prepared in Example 1, on depression was tested.
[0098] Experimental method: 40 volunteers who meet the criteria of depression were selected, regardless of gender or age. They were randomly divided into 4 groups, marked as measurement group A, measurement group B, measurement group C and blank group. The "Three Flowers Worry-Relieving Tea" A prepared in Example 1 was used for measurement group A, the "Three Flowers Worry-Relieving Tea" B prepared in Example 2 was used for measurement group B, and the "Three Flowers Worry-Relieving Tea" C prepared in Example 3 was used for measurement group C. Boiled water was used for the blank group, and 1 bag of "Three Flowers Worry-Relieving Tea" was drunk every day, 300 mL each time, for 14 consecutive days. During the period, the patient's mood scale was recorded: the Hamilton Anxiety Self-Rating (HAMA) Scale was used to assess the degree of anxiety. The total score was ≥29 points, which may be severe anxiety; 21-28 points, there must be obvious anxiety; 14-20 points, there must be anxiety; 7-19 points, there may be anxiety; <7 points, no anxiety symptoms. The Hamilton Depression Rating Scale (HAMD-24) was used to assess the degree of depression, with a total score of ≥35 points for severe depression; 21-34 points for moderate depression; 9-20 points for mild depression; and <8 points for no depression (see the table below).
[0099] Table 3 Comparison of HAMA scores before and after treatment in two groups of patients ( point)
[0100] Group Number of cases At enrollment 14 days Metering Group A 10 13.56±3.25 6.45±1.16*# Metering Group B 10 14.05±3.37 6.75±1.13*# Metering Group C 10 13.57±3.48 6.35±1.06*# Blank Group 10 14.02±3.23 13.62±3.01*
[0101] Note: Compared with the time of entry, *P<0.05; compared with the blank group, #P<0.05
[0102] Table 4 Comparison of HAMD scores before and after treatment in the four groups of patients ( point)
[0103]
[0104]
[0105] Note: Compared with the time of entry, *P<0.05; compared with the blank group, #P<0.05
[0106] Test results: 14 consecutive days of observation and comparison show that "Three Flowers Worry-Relieving Tea" has a good effect of relieving depression and regulating emotions. The "Three Flowers Worry-Relieving Tea" in the present invention has the effects of regulating qi and soothing the liver, relieving worries and relieving depression, and can be used to relieve depression.
[0107] Experimental Example 3 Animal Experiment
[0108] Experimental design: 100 SPF Wistar rats, weighing 160-200g, half male and half female, were randomly divided into 3 groups: blank group, model group, and Sanhua Jieyou tea group, with 10 rats in each group. The depression model was established by chronic psychological stress plus solitary rearing. One rat was housed in each cage and subjected to various stress stimuli, including water deprivation for 24 hours, food deprivation for 24 hours, tail clamping for 1 minute, swimming in 10℃ ice water for 5 minutes, shaking (1 time / s, lasting 5 minutes), day and night reversal, electric shock to the sole of the foot (voltage 50mV, 5s / time, interval 5s, total stimulation 10 times), one stimulus was randomly selected every day, each stimulus was used an average of 4 times, continuous stimulation every day, and the modeling time was a total of 4 weeks (28 days). After the third week of modeling, Sanhua Jieyou tea was given by gavage twice a day for 14 consecutive days. The rats were collected 2 hours after the last gavage. Rats were anesthetized with chloral hydrate, and then the spinal cord was fixed by aortic perfusion with 4% paraformaldehyde, routinely embedded in paraffin, sliced, and immunohistochemical staining for 5-HT was performed. An optical microscope (10×40 times) was used to observe the changes in the positive expression of 5-HT in the spinal cord. Using a computer image analysis system, 5 fields of view (10×40 times) were randomly selected at the same structural position of each slice, and the average IOD (cumulative optical density) value of 5-HT positive expression in the spinal cord of the random field of view was calculated, which represents the amount of 5-HT content. The larger the IOD value, the more 5-HT content. The results are shown in Table 5 below: The results show that compared with the blank group, the 5-HT level in the spinal cord of the model group increased significantly, indicating that the model was successfully established. The 5-HT level in the spinal cord of the Sanhua Jieyou Tea group was significantly lower than that of the model group, indicating that the Sanhua Jieyou Tea group has a certain effect on reducing the 5-HT level in the spinal cord of depressed animals and can improve the depressive symptoms of depressed animals.
[0109] Table 5
[0110] Group 5-HT level (IOD value) Blank Group 3945.69±126.12 Model Group 7429.91±685.87 Three flower tea group 5063±311.85
[0111] The above is only an embodiment of the present invention, and the common knowledge such as the known specific technical solutions and / or characteristics in the solution is not described in detail here. It should be pointed out that for those skilled in the art, without departing from the technical solution of the present invention, several modifications and improvements can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicality of the patent. The scope of protection required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.
Claims
1. A three-flower tea, characterized in that: The preparation method comprises the following raw materials, in parts by mass: 10 to 20 parts of mint, 10 to 20 parts of roses, 5 to 15 parts of chrysanthemums and 10 to 20 parts of chrysanthemums.
2. A three-flower tea according to claim 1, characterized in that: The weight proportions of the raw materials are as follows: 10-15 parts of mint, 10-15 parts of roses, 10-15 parts of chrysanthemums, and 10-15 parts of jasmine flowers.
3. A three-flower tea according to claim 2, characterized in that: The weight parts of each raw material are: 10 parts of mint, 10 parts of rose, 5 parts of chrysanthemum, and 10 parts of jasmine.
4. A three-flower tea according to claim 1, characterized in that: The weight parts of each raw material are: 20 parts of mint, 20 parts of rose, 15 parts of chrysanthemum, and 10 parts of jasmine.
5. The method for preparing three-flower tea according to any one of claims 1 to 4, characterized in that: The steps include: Step 1: Material selection: Choose authentic medicinal materials such as mint, rose, chrysanthemum, and chrysanthemum; Step 2: Cleaning and drying: Wash with water and then dry; Step 3: Mix and grind: Mix and grind according to the proportion to get Sanhua Tea.
6. The method for preparing three-flower tea according to claim 5, characterized in that: In step 2, the drying temperature is 30-45°C and the drying time is 1-2h.
7. The method for preparing three-flower tea according to claim 6, characterized in that: In step 3, the particle size after grinding is 1 to 5 mm.
8. Use of the three-flower tea according to any one of claims 1 to 4 in the preparation of liver-soothing and qi-regulating medicines.