678 results about "Herpes zoster disease" patented technology

Methods for treating conditions in an animal or human subject. The conditions may be pain, skeletal muscle conditions, smooth muscle conditions, glandular conditions and cosmetic conditions. The methods comprise the step of administering a Clostridium neurotoxin component or Clostridium neurotoxin component encoding DNA to the subject using a needleless syringe.

A method of treating shingles in a human in need thereof. The method comprises administering a tetracycline compound in an amount that is effective to treat shingles, but has substantially no antibacterial activity.

The invention discloses a topical skin composition, the preparation method and application in the treatment of psoriasis, herpes zoster and neuro dermatitis, which comprises (a) an acceptable carrier in pharmacy, and (b) effective dose of water extract of raw herbal materials or extract of waterborne organic solution; wherein, the raw herbal materials comprises goldenrod, clove, radixstemonae, seed of cowherb, pseudolari cortex, pubescent holly, glycyrrhiza, dictamnus dasycarpus, angelica sinensis, safflower, gleditsia sinensis lam, uncaria, cynachum paniculatum and Chinese yam.

Solid, pharmaceutical dosage forms of [2-(8,9-dioxo-2,6-diazabicyclo [5.2.0]non-1(7)-en-2-yl)alkyl]phosphonic acid and derivatives thereof are disclosed. In addition, methods of use are disclosed for the treatment, inter alia, of cerebral vascular disorders, anxiety disorders; mood disorders; schizophrenia; schizophreniform disorder; schizoaffective disorder; cognitive impairment; chronic neurodegenerative disorders; inflammatory diseases; fibromyalgia; complications from herpes zoster; prevention of tolerance to opiate analgesia; withdrawal symptoms from addictive drugs; and pain.

A preparation for transdermal absorption is disclosed which is suited for alleviating lasting pains caused by herpes zoster or postherpetic neuralgia and is practical and more improved in drug efficacy, safety and application characteristics. This tape preparation for transdermal absorption is obtained by causing an adhesive mass prepared by incorporating 1–30 parts by weight of a local anesthetic as an active ingredient in 100 parts by weight of a nonaqueous adhesive mass base comprising 5–50% by weight of a styrene-isoprene-styrene block copolymer, 1–60% by weight of an alicyclic saturated hydrocarbon resin, 5–60% by weight of liquid paraffin and 1–30% by weight of butyl rubber to be supported on a backing.

In one embodiment, the present invention provides a topical composition including a topically acting anesthetic active ingredient; an ester; a non-ionic surfactant; a polar solvent; water, and optionally a buffer, a pH adjusting agent or an anti-oxidant. The compositions are useful for alleviating pain especially associated with acute herpes zoster.

An analgesic composition, is disclosed which comprises a mixture of piroxicam, dexamethasone, ketamine, lidocaine injection, dimethyl sulfoxide, gabapentin and Vanicream™, preferably in the form of a cream or ointment. The composition is applied topically for the relief of pain of arthritis, neuropathy, post-herpetic (shingles) conditions, sore muscles, tendons and ligaments, and local reactions to insect bites or stings.

A Chinese medicine for treating herpes zoster and various diseases caused by stagnated dampness and heat toxicosis is prepared through 24 Chinese-medicinal materials including Sichuan chinaberry, Chinese gentian, dandelion, red sage root, Chinese violet, etc. Its advantages are high curative effect and cure rate, short course of treatment, and quickly taking its effect.

Methods and compositions are offered for reducing nerve injury pain associated with shingles (herpes-zoster and post-herpetic neuralgia), where intradermal delivery of lidocaine is maintained for a predetermined period of time. The lidocaine appears to specifically affect the damaged nerve fibers, while leaving the undamaged and normal nerve fibers with retention of response to other stimuli. Lidocaine formulations are provided which allow for the necessary dosage of the lidocaine in the dermis during the period of treatment. The formulation may be covered with an occlusive or non-occlusive dressing, which protects the lidocaine formulation from mechanical removal and enhances the transport of the lidocaine into the dermis. Long term relief is realized after maintenance of the administration of lidocaine has been terminated.

The present invention provides novel compositions which comprise sodium hypochlorite, sodium, chloride, both organic and inorganic trace minerals in hypertonic condition presented in the forms of a clear aqueous solution (low or high concentrations for further reconstitution with purified water to obtain the final ready-to-use solution), gel or salve, lotion, wet pad, wet foam, ointment, stick, and dry mixture solution, for local application for the purposes of cleansing, disinfecting and inhibiting infection and promoting the natural healing of conditions such as fresh cuts, surgical stitches, chronic (diabetic gangrene) and acute wounds, herpes zoster, athlete's foot, and bed sores, without the necessity for covering up the wounds with gauzes / plasters nor any concurrent use of topical medication. These compositions are also suitable for the treatment of conditions such as unpleasant body odor, acne and mixed bacterial infection in the ear.

The invention discloses a herpes zoster vaccine, and a preparation method and an application thereof, and belongs to the field of vaccines. The herpes zoster vaccine is provided against the problem ofhigh safety risk of existing herpes zoster vaccines, and an adjuvant used by the herpes zoster vaccine is Poly (I:C). The Poly(I:C) is called polyinosinic-polycytidylic acid for short, and is double-stranded RNA, and the safety of the Poly(I:C) is confirmed during large-scale clinical application. The Poly(I:C) is a high-efficiency interferon inducer, can produce an immune reaction like viral infection in vivo, and can induce CD4<+> and CD8<+> T cells and enhance cellular and humoral immune responses.

The invention belongs to the field of medicines and particularly relates to a new application of an iridoid glycoside compound, genipin-1-[beta]-D-gentiobioside, and a composition composed by compounding the genipin-1-[beta]-Dgentiobioside with other components as effective components for preparing antiviral drugs, antibacterial drugs, fever alleviating drugs, inflammation resistant drugs and anti-oxidizing drugs. The iridoid glycoside compound and the composition can be used for treating acute respiratory infection, flu, pneumonia, viral hepatitis type B, herpes zoster, herpes viral keratitis, viral myocarditis, Epstein-Barr virus infection, retrovirus infectious diseases and bacterial infectious diseases.

A composition and regimen for the treatment of herpes simplex and herpes zoster, primarily through elimination of the pathogenetic conditions by taking into account both pathogenesis and etiology thereof are disclosed. Administration of 1) repeated large dosages of vitamin B2 to eliminate severe vitamin B2 deficiency inherent in herpes simplex and herpes zoster; 2) Strobilanthes cusia and Berberine to ameliorate febrile illness and to clear “hot” condition; 3) Zizyphus semen to relieve psychological stress; and 4) L-lysine to antagonize arginine and alleviate anxiety-all these hereof are for eliminating the pathogenetic conditions. These, in combination with antiviral agents if necessary, constitute the scope and the spirit of the present invention.

The herpes zoster treating external applied medicine is prepared with 22 kinds of Chinese medicinal materials, including gentian root, corktree bark, skullcap root, red peony root, gromwell, etc. in certain weight proportion and through soaking in medical alcohol. It has the functions of clearing away heat, drying damp, cooling blood, promoting blood circulation, dissipating blood stasis, etc. It is used mainly in treating herpes zoster and has fast acting, high healing rate and less recurrence. It may be also used in treating common skin diseases to result in high healing effect.

The invention discloses a medicine for curing herpes zoster, which is composed of following raw materials: Baical Skullcap Root 12, Gardenia 12, taraxacum 12, Chinese violet 15, wild chrysanthemum 15, Coptis Root 15, phellodendron 15, honeysuckle 15, Andrographis paniculata 18, red paeonia 18, moutan bark 18 and rhubarb 10; utilizing the medicine can cure the herpes zoster with obvious effects, rapid recovery, few side effects and little recrudescence with a effective ratio of 95% and a recovery ratio of 90%.

The invention discloses multiple real-time quantitative PCR primer, probe and a detection method for identifying viral pathogens relevant to fevers with eruption syndromes as infection diseases, which is used for carrying out multiple real-time fluorescent quantitative PCR detection on varicella-herpes zoster viruses, human small DNA (Deoxyribonucleic Acid) viruses B19, enteroviruses (enteroviruses 71 type and coxsackie viruses A16 type), dengue viruses, rubella viruses and measles viruses. The invention can simultaneously carry out qualitative or quantitative detection on eight kinds of human viruses in various types of samples by multiple double-tubes PCR. The detection method has the advantages of simple operation, short time consumption, high sensitivity and strong specificity, is suitable for field detection, early diagnosis, epidemics detection and research and the like, and takes the actions of assistance and identification diagnosis on the fevers with eruption syndromes.

A composition and treatment regimen for the amelioration of epidermal herpetic lesions caused by Herpes Simplex Virus (HSV-1) symptoms, Herpes Zoster, and Herpes Genitalia. The treatment includes a regimen of oral administration of a composition including from about 15 to 50 mg of zinc sulfate, from about 5 to 20 mg of magnesium sulfate, from about 15 to 60 mg of thiamin, from about 10 to 30 mg of riboflavin, from about 4 mg to 12 mg of pyridoxine hydrochloride, from about 300 to 1000 mg of ascorbic acid, from about 90 to 300 mg of niacin, and from about 20 to 70 mg of pantothenic acid. The composition and regimen may optionally include an efficacious amount of an amino acid, and preferably about 500 mg of lysine.

The invention discloses Chinese medicinal ointment for treating herpes zoster and a preparation method thereof, which belong to the technical field of Chinese medicinal ointment. The Chinese medicinal ointment consists of mongolian snakegourd root, red paeony root, cape jasmine fruit, baical skullcap root, amur corktree bark, rhubarb, swordlike atractylodes rhizome, officinal magnolia bark, tangerine peel, dahurian angelica root, curcuma longa, rhizoma kaempferiae, Chinese gall, flos caryophyllata, borneol, orpiment, alum, grilled nux vomica, centipede, myrrh, white pepper, yunnan manyleaf paris rhizome, raw arisaema root, raw pinellia rhizome and honey. According to the treatment principle of clearing heat and promoting diuresis, soothing liver-gallbladder, detoxicating and removing blood stasis, removing obstruction in channels to relieve pain, and purging the spleen and eliminating dampness, the Chinese medicinal ointment is selectively used aiming at the pathogeny and symptom of each patient during clinical treatment; the Chinese medicinal ointment has precise, appropriate and reasonable compatibility, and can be absorbed well by skins through the synthetic action of the medicaments; and after being absorbed, the medicaments perform function in vivo with blood circulation; the Chinese medicinal ointment has quick response, can treat the herpes zoster effectively and alleviate the pain of patients, and has the curative rate of 99 percent.

The invention discloses a traditional Chinese medicine composition for treating herpes zoster by oral administration and external administration, which belongs to the field of traditional Chinese medicines. This kind of Chinese medicine composition for oral administration plus external application for treating herpes zoster is characterized in that the raw materials forming the active ingredients are by the following weights: 30g of honeysuckle, 15g of Radix Radix, 10g of Desmodium, 15g of wild chrysanthemum, 10g of forsythia, 15g of dandelion, Paeonol 10g, Radix Paeoniae Rubra 10g and Raw Licorice 10g. Decoction orally in 2 times. In addition, the dregs are decocted and washed with water to wash the affected area. The medicine of the present invention is a two-pronged approach of oral administration and external application, and has been clinically verified to have the characteristics of fast pain relief, fast scab formation, anti-virus, anti-infection, and no toxic and side effects during the treatment of herpes zoster.

The invention discloses an oral administration pharmaceutical composition for treating herpes zoster, which is prepared from lysimachia christinae, arctium fruit, Schizonepeta tenuifolia, goldthread root, baikal skullcap root, honeysuckle flower, capsule of weeping forsythia, corktree bark, isatic root, wild chrysanthemum flower and licorice root. The medicament should be decocted in water for the oral dose.

The invention provides a collateral dredging and inflammation diminishing analgesic ointment, and relates to medicines for treating herpes zoster, scapulohumeral periarthritis and traumatic injuries. The ointment comprises the following medicinal materials: Chinese angelica, red peony root, raw rehmmania root, radix scrophulariae, scutellaria baicalensis, coptidis rhizoma, cortex phellodendri, rheum officinale, lonicera japonica, earthworm, ligusticum wallichii, gecko, ground beetle, leech, safflower, camphor, angelica root, pangolin, frankincense, myrrh, dragon's blood, catechu, fructus forsythiae, nidus vespae, liquorice and borneol. The ointment is prepared by the following steps: soaking raw materials except borneol in 2.0-2.4kg of sesame oil for 5-7 days; decocting until the mixture is black with slow fire; removing dregs, adding 1.0-1.2kg of yellow lead, and keeping on decocting until the dropping mixture forms a bead shape; removing from the fire and cooling; adding borneol into the mixture, uniformly stirring, and spreading into patches. The collateral dredging and inflammation diminishing analgesic ointment has the advantages that the treatment effect is good, the cure rate is high, one patch of the ointment is used for 3 days and can be used for relieving pains in 8-12 hours, pains can be cured in 3 days generally, and certain individual syndromes need two patches and can be cured in 6 days; sequelae are not left; clinical testing on 229 cases indicates that the effective rate of the ointment is 100 percent; the ointment is prepared by using a pure traditional Chinese medicinal formula, and has small toxic and side effects.

The present disclosure relates to substituted amide compounds that are inhibitors of Fatty Acid Amide Hydrolase (FAAH), their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions containing them. These compounds are useful in the treatment, prevention, prophylaxis, management, or adjunct treatment of all medical conditions related to inhibition of Fatty Acid Amide Hydrolase (FAAH), such as pain including acute and post operative pain, chronic pain, cancer pain, cancer chemotherapy induced pain, neuropathic pain, nociceptive pain, inflammatory pain, back pain, pain due to disease of various origin such as: diabetic neuropathy, neurotropic viral disease including human immunodeficient virus (HIV), herpes zoster such as post herpetic neuralgia; polyneuropathy, neurotoxicity, mechanical nerve injury, carpal tunnel syndrome, immunologic mechanisms like multiple sclerosis; sleep disorders, anxiety and depression disorders, inflammatory disorders, weight and eating disorders, Parkinson's disease, addiction, spasticity, hypertension or other disorders. The disclosure also relates to the process of preparation of the amide compounds. Formula (1). The present disclosure also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.

The invention discloses gel for treating herpes zoster. The gel is prepared from the following raw materials in percentage by weight: 2-4 percent of acyclovir, 1-3 percent of lidocaine hydrochloride, 0.05-0.15 percent of tacrolimus, 0.04-0.06 percent of vitamin B12, 0.5-1.5 percent of a gel substrate, 1-1.5 percent of a neutralizer, 4-6 percent of a moisturizer, 25-35 percent of a solvent, 1-3 percent of a solubilizer, 0.5-1.5 percent of an absorption enhancer and the balance of water. The gel substrate is any one or more of carbopol 940, hydroxypropyl methyl cellulose, alginate, gelatin or starch; the neutralizer is triethanolamine or sodium hydroxide; the moisturizer is glycerin; the solvent is ethyl alcohol; the solubilizer is tween-80; the absorption enhancer is laurocapram. The invention also discloses a preparation method of the gel. All medicine components in the gel have a synergistic effect, the dosage of the medicines can be reduced, and the adverse reaction of the medicines is reduced.

The invention relates to a medicament for treating herpes zoster, which is prepared by the following bulk drugs in part by weight: 7 parts of gentian, 15 parts of giant knot weed, 7 parts of honeysuckle flower, 10 parts of platycodon grandiflorum, 15 parts of isatis indigotica fort, 15 parts of poria cocos, 7 parts of scutellaria baicalensis, 10 parts of fructus forsythiae, 10 parts of Chinese pearl barley, 10 parts of common clubmoss herb, 15 parts of salvia miltiorrhiza, 10 parts of nutgrass galingale rhizome, 12 parts of radix angelicae and 5 parts of liquorice. The medicament can relieve all the symptoms of the herpes zoster, can cure the herpes zoster basically after use, and also has the advantages of difficult relapse, very obvious effect, no toxic and side effect, short treatment course and low cost.

An exterior-applied Chinese medicine for treating herpes zoster, herpes gestationis and herpes simple is prepared from 5 Chinese medicinal materials including realgar, coptis root, borneol, musk, etc. according a certain proportion through compounding. Its advantages are high cure rate up to 92%, high total effective rate up to 98%, and not toxic by-effect.

An interior-applied Chinese medicine for treating herpes zoster is proportionally prepared from portulaca, dandelion herb, isatis leaf and corydalis tube.

The invention relates to a multifunctional laser therapeutic instrument, and in particular relates to a laser therapeutic instrument which is adjustable in multiple operating modes. The laser therapeutic instrument can be controlled by hand-holding and pedaling, and adopts different wave lengths or therapy modes according to the purpose of disease treatment to achieve the therapy on various diseases. The laser therapeutic instrument includes the laser with wave band of 760nm-1400nm width, and meanwhile can freely change the diameter of an irradiating spot to be applicable to treating large pain area with respect to arthritis, nerve oppressed by spinal and cervical bone hyperplasia and herpes zoster caused by inflammation.

The invention discloses a capsule capable of clearing heat and purging fir, which is a Chinese medicine preparation having the effects of clearing heat and drying dampness, and purging fire and removing toxicity. The capsule is prepared by taking radix gentianae, radix isatidis, scutellaria baicalensis georgi, gardenia, rhizoma corydalis, angelica, rehmannia glutinosa, radix bupleuri, semen plantaginis, caulis clematidis armandii, Alisma orientalis, rhizoma cyperi and glycyrrhiza uralensis as raw materials, crushing, decocting, filtering, drying, screening and the other procedures. The capsule of the invention is used for treating herpes zoster, eczema and other diseases, has significant curative effect and fills a gap of the medicaments in the market.

The invention discloses a method for preventing or treating conjunctivitis and herpes zoster palpebral dermatitis, bear gall powder used by the method, and a preparation method of the bear gall powder. The bear gall powder can be used for regulating blood lipid, lowering total cholesterol, preventing cardiovascular and cerebrovascular diseases and preventing atherosclerosis. Materials are subjected to ice crystallization during the preparation of the bear gall powder, and then freeze drying is performed to obtain the freeze-dried bear gall powder which can be called ice-crystalized bear gall powder. The Senbao ice-crystalized bear gall powder does not contain any auxiliary materials and chemical additives, can effectively regulate the blood lipid and lower the total cholesterol, can be effectively used for preventing cardiovascular and cerebrovascular diseases and atherosclerosis and preventing and treating solid tumor and blood system tumor, and can be particularly effectively used for preventing or treating the conjunctivitis and herpes zoster palpebral dermatitis.

The invention relates to an external use Chinese traditional medicine preparation for curing virosis of herpes zoster and herpes simplex, which is composed of the following materials: coptis root 25-25g, rhubarb 25-25g, Mongolian Dandelion Herb 25-25g, oriental tuckahoe 25-25g, frankincense 25-25g, myrrh 25-25g, angelica 10 to 20g, Panax pseudoginseng 5 to 15g, gallnut 25-25g, whole worm 25 to 25g, Jiuxiang Bug 5 to 15g, woody nightshade 25 to 25g, Black-snake 10 to 20g, borneol 5 to 15g, Bletilla striata 25 to 25g and ethanol 400 to 600g; the preparing method is that: the above components are smashed into powder and dipped in ethanol through decocting and filtering; the decoction liquid can be mixed and then packed in sealing way. The medicine preparation is the external use medicine which takes the Chinese tradition medicines as materials; and can be directly coated on the affected part; can clear away heat and toxic material and remove blood stasis and promote scab; thus having popularizing and application value.