238 results about "Cerebral vascular disorders" patented technology

The composition of Chinese patent medicine for curing cardio-cerebral vascular diseases comprises (wt%) 82-87% of bran and coarse grain, 13-18% of plant medicinal material for curing cerebrovascular disease and microscale of saccharifying enzyme and lactobacillin, which is characterized by that the composition of said plant medicinal material comprises (wt%) 28-37% of main medicinal material, 23-30% of secondary medicinal materials, 27-41% of auxiliary medicinal material and 5-7% of flavouring material, and its preparation method includes the following steps: selecting materials, pulverizing,mixing, steaming, cooling, inoculating, showering, sterilizing, filtering, inspection, packaging and putting in storage.

The present invention discloses thiopheno pyridine substituted acetyl hyarazine derivative compound as shown in expression I and its pharmaceutically acceptable salt, medicine composition with the compound as effective component, and their application as platelet aggregation resisting medicine, especially as medicine for preventing and treating platelet aggregation caused coronary artery syndromes, myocardial infarction, myocardial ischemia and other cardiac and cerebral vascular diseases.

Solid, pharmaceutical dosage forms of [2-(8,9-dioxo-2,6-diazabicyclo [5.2.0]non-1(7)-en-2-yl)alkyl]phosphonic acid and derivatives thereof are disclosed. In addition, methods of use are disclosed for the treatment, inter alia, of cerebral vascular disorders, anxiety disorders; mood disorders; schizophrenia; schizophreniform disorder; schizoaffective disorder; cognitive impairment; chronic neurodegenerative disorders; inflammatory diseases; fibromyalgia; complications from herpes zoster; prevention of tolerance to opiate analgesia; withdrawal symptoms from addictive drugs; and pain.

A liposome of breviscapine for preparing the medicines to cure cerebral thrombus and coronary heart disease is prepared from breviscapine, phosphatide, cholesterol, and supporting agent chosen from sorbitol, mannitol, cane sugar, sodium chloride, water-soluble starch, etc by different methods. Its advantages are high absorption rate, high biologic utilization rate, and high stability.

The present invention relates to a compound medicine for preventing and curing angiocardiopathy and cerebrovascular disease, belonging to the field of chemical medicine. It is characterized by that said compound medicine includes sexual hormones medicine, lipid-reducing medicine, hypotenser, hypoglycemic medicine and anticoagulant medicine. Said compound medicine can be made into various dosage forms. Besides, said compound medicine also can be used for curing the diseases of climacteric syndrome, osteoporosis, endometrial carcinoma, diabetes and metabolic syndrome, etc.

The present invention relates to, among other things, methods for treating trigeminal cephalgias such as migraine and migraine like headaches and other cerebrovascular conditions associated with pain and or inflammation. When non-steroidal anti inflammatory drugs (NSAIDs), such as ketoprofen, are applied locally using specific topical formulations immediate relief of pain is obtained. Intense pain is typically reduced to mild pain or no pain within 30 minutes of application of the topical formulation. The NSAID may be given in combination with other pharmacological agents, such as vasoconstrictors, opioids, decongestants and/or non-opioid migraine drugs, such as triptans and ergots and agents that affect serotonin receptors as agonists, antagonists or partial agonists.

The present invention provides one kind of total paeonoside extract and its preparation process as well as the application of the total paeonoside extract in preparing medicine for preventing and treating cardiac and cerebral vascular diseases. Specifically, the total paeonoside extract is used in preparing medicine for preventing and treating cerebral apoplexy, cerebral ischemia/re-perfusion damabe, brain trauma, senile dementia, etc.

The invention discloses a Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, which comprises 5.0-80.0% of danshensu extract containing danshensu 50-98%, 15.0-93.0% of pseudo-ginseng extract containing total notoginsen triterpenes 70-98%, and natural borneol or rosewood oil 2.0-15.0%. The composition has evident functions in resisting cerebral ischemia and myocardial ischemia, the curative effect is better than the application of single extract of red sage root or notoginseng, thus providing a more effective and more convenient Chinese medicinal composition and preparation clinically.

The invention discloses a medicinal composition for preventing and treating cardiac and cerebral vascular diseases, consisting of antler blood, ginseng, milkvetch root, Chinese angelica, Chinese caterpillar fungus, medlar, fleeceflower root, manyprickle acathopanax root, fiveleaf gynostemma herb, red sage root, safflower, lucid ganoderma, red paeony root, Szechuan lovage rhizome, earthworm, pueraria root, amber, hawthorn, algae, rose flower, tall gastrodia tuber and bear gall. The medicinal composition has the functions of adjusting the immunity of the organism and the functions of a neuroendocrine system, improving the circulation of cerebral blood substances, reducing the blood fat and blood viscosity, improving the brain function, preventing and treating the cardiac and cerebral vascular diseases, delaying the ageing and the like. The medicinal composition can prepared into capsules, tablets, granules, pills, soft capsules and other dosage forms.

The invention discloses a series health-care food containing pearl and kudzu root and a preparation method thereof. The food is prepared by matching natural pearl and kudzu root which can be taken both as food and medicine with vitamin, medlar, a sweetening agent and appropriate accessories according to a certain proportion. The health-care food contains organic calcium, inorganic calcium, vitamin and a plurality of trace elements which are needed by human body, and the food further contains components such as flavonoid daidzin, daidzein, xylopuerarin, kudzu powder flavin, and great amount of starch, therefore, the food has the functions of beautifying the face and enlarging the breast, nourishing the tendons and channels and preventing cerebral-cardiovascular diseases, and is taken as health products which are fit for women, the middle aged people and the old, thus delaying senility, strengthening the body and maintaining the beauty and youth of skin.

The invention belongs to the technical field of medicines and relates to the use of the chitosan oligosaccharide in the preparation of medicines for preventing and treating cardiovascular and cerebrovascular diseases. Pharmacodynamic experiments prove that chitosan has remarkable effect of resisting cerebral ischemia, cerebral anoxia and the like, is widely available, can be absorbed easily by bodies, has small toxic and side effects and has a bright application prospect.

The invention relates to the field of medical technology, which discloses a new usage of a petasites tricholobus franch extract and the contained bakkenolide compound in the preparation of drugs for prevention and treatment for cardiovascular and cerebrovascular diseases. The biological activity tests show that, the petasites tricholobus franch extract and the contained bakkenolide compound can significantly reduce the encephalic necrosis percentage of the rats with local cerebral ischemia, improve the behavior score of the ischemic rats and alleviate volume of brain edema and cerebral infarction of the rats with ischemia reperfusion injury, thus prompting that the petasites tricholobus franch extract and the contained bakkenolide compound have significant protective effect on the cerebral ischemia injury. The petasites tricholobus franch extract and the contained bakkenolide compound can further significantly reduce the J-point displacement caused by ISO and the LDH level in plasma, significantly reduce the scope of myocardial ischemic myocardial infarction of the rats caused by coronary artery ligation and lower the LDH level in the plasma of the rats with the myocardial ischemia. As the petasites tricholobus franch extract and the contained bakkenolide compound have good effects on the prevention and the treatment for heart and brain ischemic diseases aspects, the petasitestricholobus franch extract and the contained bakkenolide compound can be used in the preparation of drugs for prevention and treatment for cardiovascular and cerebrovascular diseases, including coronary heart disease, cerebral ischemia, cerebral infarction (stroke), myocardial infarction and so on.

The present invention is dispersive red yeast tablet prepared via advanced preparation process and has high bioavailability. Compared with available red yeast preparations, the dispersive red yeast tablet has the features of fast disintegration, fast effective component effusion, high bioavailability, high clinical effect, etc. The dispersive red yeast tablet of the present invention is suitable for cardiac and cerebral vascular diseases patients, especially the patients with acute attack of cardiac and cerebral vascular diseases and difficulty in swallowing solid medicine preparation, and may be used as substitute of the available red yeast preparation.

The invention discloses a medicinal composition containing weinaolutong (7, 3', 4'-troxerutin) obtained by hydroxyethylating eldrin and brain extract which is extracted form brain tissue of mammalian except human. The medicinal composition contains 1 to 1000 parts of weinaolutong, by weight, and the weight of the weinaolutong in the medicinal composition is 0.1 to 200 times bigger than total nitrogen content in the brain extract. The invention also discloses preparation method and use of the medicinal composition. The medicinal composition can restrain platelet agglutination thereby preventing thrombosis, and can regulate and improve brain supersession, and is used for treating acute and chronic cerebrovascular disease and sequela such as brain dysfunctional caused by craniocerebral trauma and cerebrovascular disease; and can also be used for treating occlusive syndrome, arteriosclerosis, thrombosis phlebitis, capillary bleeding and dropsy caused by elevation of vascular permeability.

The invention belongs to the field of research and development of traditional Chinese medicines and particularly relates to a Chinese medicinal formulation containing effective fractions for treating cerebrovascular diseases. The Chinese medicinal formulation is developed based on the compatibility theory of traditional Chinese medicine in combination with the modern pharmacodynamic screening and implemented by composition-effectiveness relationship, component compatibility, optimum design and modern pharmaceutical techniques. The Chinese medicinal formulation contains Radix Paeoniae Rubra effective fraction (total glycosides of Radix Paeoniae Rubra) and Herba Erigerontis effective fraction (total flavonoids and total caffeates of Herba Erigerontis) and is characterized and advantageous in synergistic effect. The pharmacodynamic experimental result shows that the Chinese medicinal formulation can improve cerebral ischemia, increase the brain blood flow, and inhibit platelet aggregation, and is superior in protection against cerebral ischemia to the similar products available in the market.

The gingko medicine composition consists of gingko leaf extract and ligustrazine phosphate in the amount of 1-100 times of gingko leaf extract. The preparation process of the medicine composition is also disclosed. As the compound preparation, the medicine composition of the present invention has the complementary and synergistic effects of gingko leaf extract and ligustrazine phosphate, including promoting blood circulation to disperse blood clots, resisting platelet aggregation, dilating blood vessel and improving microcirculation, and may be used in preparing medicine for ischemic cardiac and cerebral vascular diseases.

The invention discloses a processing method of dendrobe health care black tea. A processing technique comprises sorting, cleaning, withering, rolling, incipient drying and re-firing drying. In the technical scheme, room temperature heavy-withering, medium-temperature incipient drying and high temperature re-firing technologies are adopted, overmuch organic acid forming ways caused by fermentation and a high temperature incipient drying process in the traditional technique are avoided, the high temperature re-firing technique is adopted to basically remove herbal flavour of dendrobe leaves and achieve representative high-fired fragrance and sweetness, and thus the dendrobe tea processed in this way is tight in twig, reddish brown and glossy in color, mellow in taste, and good, fragrant and sweet in aftertaste, has effects of nourishing yin and boosting essence, beautifying and detoxifying, nourishing the stomach and intestine, and improving eyesight, and has perfect improvement effects in improving immunity, and relieving insomnia, cardiovascular disease and diabetes.

The novel safflower medicine composition is medicine preparation prepared with acetyl glutamine and Chinese medicinal material safflower in the amount of 1-50 times weight of acetyl glutamine. The present invention also discloses the preparation process and use of the medicine composition. By means of the complementary and synergistic effect of both acetyl glutamine and Chinese medicinal material safflower, the medicine composition has the e of promoting blood circulation to disperse blood clots and improving brain metabolism and brain function and may be used in treating coma, paralysis, hypophrenia, memory impairment and other diseases caused by obliterative cerebral vascular diseases, hepatic coma, hemiplegia, etc. It may be also used in treating coronary heart disease, angeitis and other diseases.

The present invention is the application of white flower red sage in preparing medicine and the preparation process of white flower red sage medicine. White flower red sage has danshensu content as high as 2 times that of purple flower red sage, and danshensu is the main effective component for treating cardiac and cerebral vascular diseases and other relevant diseases, and possesses the functions of promoting blood circulation to disperse blood clots, relieving pain, dredging meridian and clearing away heart fire. The white flower red sage medicine has high curative effect on various cardiac and cerebral vascular diseases, and may be also used in treating pulmonary heart disease, viral myocarditis, hypertension, etc.

An application of the asiaticoside in preparing the medicines in the form of capsule, tablet, particle, or injection for preventing and treating the cardiovascular and cerebrovascular diseases, such as coronary heart disease, angina pectoris, myocardial infarction, etc. is disclosed.

The invention discloses a medicament for treating cardiovascular and cerebrovascular diseases and a preparation method of the medicament. The medicament is prepared from a ginseng extract, a red-rooted salvia root extract and a hemlock parsley extract according to a certain weight proportion, wherein the ginseng extract, the red-rooted salvia root and the hemlock parsley extract can be obtained by commercial way or extracted from medicinal materials. The medicament can be prepared to form any pharmaceutically acceptable dosage form, preferably drop pills. The medicament has effects of tonifying qi and activating blood circulation, can be used for treating cardiovascular and cerebrovascular diseases, in particular treating in acute and early recovery phase of cerebral thrombosis, cerebral ischemia, cerebral infarction and other ischemic cerebrovascular diseases.

A Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases, such as cerebral infarction, cerebral ischemia, coronary heart disease, etc is prepared from red sage root, Chuan-xiong rhizome and pharmacologically acceptable carrier. It contains darshinolic acid, cnidiumol and ferulaic acid. Its preparing process is also disclosed.

The medicine preparation for treating cardiac and cerebral vascular diseases is prepared with honeysuckle, achyranthes root, figwort and dendrobium stem as material. The preparation process includes extracting honeysuckle with extracting agent to obtain effective honeysuckle part; water extracting and alcohol depositing achyranthes root, figwort and dendrobium stem and extracting the solution to obtain the first effective part of achyranthes root, figwort and dendrobium stem; purifying the deposit to obtain the second effective part of achyranthes root, figwort and dendrobium stem; compounding the said effective parts to obtain injection; or adding osmotic pressure regulator and injection water to obtain transfusion liquid; or adding excipient and freeze drying to obtain medicine powder for injection. The medicine preparation has high curative effect on ischemic apoplexy, coronary heart disease, angina pectoris, etc.