Medicinal composition, its preparation method and its use

A composition and drug technology, applied in the direction of drug combination, drug delivery, pharmaceutical formulation, etc., can solve the problems not involving Vinaorutong, etc., and achieve the effect of improving brain metabolism
CN1589811AActive Publication Date: 2005-03-09JILIN SIHUAN PHARM CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
JILIN SIHUAN PHARM CO LTD
Publication Date
2005-03-09

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Abstract

The invention discloses a medicinal composition containing weinaolutong (7, 3', 4'-troxerutin) obtained by hydroxyethylating eldrin and brain extract which is extracted form brain tissue of mammalian except human. The medicinal composition contains 1 to 1000 parts of weinaolutong, by weight, and the weight of the weinaolutong in the medicinal composition is 0.1 to 200 times bigger than total nitrogen content in the brain extract. The invention also discloses preparation method and use of the medicinal composition. The medicinal composition can restrain platelet agglutination thereby preventing thrombosis, and can regulate and improve brain supersession, and is used for treating acute and chronic cerebrovascular disease and sequela such as brain dysfunctional caused by craniocerebral trauma and cerebrovascular disease; and can also be used for treating occlusive syndrome, arteriosclerosis, thrombosis phlebitis, capillary bleeding and dropsy caused by elevation of vascular permeability.
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Description

technical field

[0001] The present invention relates to a pharmaceutical composition, its preparation method and its application, in particular to a pharmaceutical composition of brain extract extracted from the brain tissue of mammals other than humans and venaolutong, and its preparation The method and its use in the preparation of medicines for treating acute and chronic cerebrovascular diseases and the sequelae caused by them, such as brain dysfunction. Background technique

[0002] Vinaolutong (also known as troxerutin) is a water-soluble flavonoid compound obtained by semi-synthesis of rutin through hydroxyethylation. D)-based mixture of hydroxyethyl rutin, generally used for medicine, calculated as anhydrous substance, containing troxerutin (C 33 h 42 o 19 ) shall not be less than 80.0% (for injection) and 60.0% (for oral use). Vinaorutong can inhibit the aggregation of platelets and has the effect of preventing thrombosis. At the same time, it can resist vascula...

Claims

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