Medicinal composition with synergetic function

A composition and drug technology, applied in the field of medicinal compositions containing natural plant extracts or monomers, can solve problems such as no suggestion or attempt, no scientific basis provided, etc.

Active Publication Date: 2006-01-04
YUNNAN BIOVALLEY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] What is even more unfavorable is that so far, the existing technology has not provided scientific basis for the basic issues such as whether ginkgo can be used in combination with peony and whether the mechanism of action of the two is additive, synergistic or antagonistic.
As for whether the two can be used in combination for other diseases (such as diabetes, Alzheimer's disease), there is no similar suggestion or attempt in the prior art

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0159] Example 1 Capsules

[0160] Take 5 g of Ginkgo biloba extract (purity 97%, wherein flavonoids contain 24%, lactone 6%), take 5 g of Radix Paeoniae Rubra extract (containing 20% ​​paeoniflorin), add starch, mix well, granulate, pulverize and sieve , dried to obtain granules, and packed into 20 hard capsules. After testing, each capsule contains 15 mg of ginkgolide and 50 mg of paeoniflorin.

Embodiment 2

[0161] Example 2 tablet

[0162]Take 8g of ginkgolides and 60g of paeoniflorin, grind them into fine powder and pass through an 80-mesh sieve, add appropriate amount of dextrin, mix well, first wet with 40-60% ethanol, then granulate with starch slurry, sieve and dry at 80°C, The whole powder (passed through a 14-mesh sieve) is uniformly mixed with magnesium stearate into the granules with a 100-mesh sieve to prepare 1000 tablets, and then coated. After testing, each tablet contains 8mg of ginkgolide and 60mg of paeoniflorin.

Embodiment 3

[0163] Embodiment 3 soft capsules

[0164] Take 40 g of ginkgo flavonoids and 20 g of paeoniflorin, add them into vegetable oil and mix evenly, use gelatin as the capsule shell material, and press into 1000 soft capsules. After testing, each capsule contains 40 mg of ginkgo flavonoids and 20 mg of paeoniflorin.

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PUM

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Abstract

The present invention relates to a kind of medicine composition, and its preparation process and application. The said medicine composition contains mainly bilobalide and paeoniflorin. The medicine composition of the present invention may be used in treating and preventing diabetes, senile dementia and cardiac and cerebral vascular diseases and in preventing recurrence of cardiac and cerebral vascular diseases.

Description

technical field [0001] The present invention relates to a pharmaceutical composition, specifically, a pharmaceutical composition containing natural plant extracts or monomers, used for treating and / or preventing cardiovascular and cerebrovascular diseases, diabetes, Alzheimer's disease, and for preventing Recurrence of cardiovascular and cerebrovascular diseases. Background technique [0002] With the rapid development of modern science, people pay more and more attention to "natural" medicines. In recent years, the medical community has done a lot of work in the research of medicinal plants for the prevention and treatment of cardiovascular and cerebrovascular diseases, diabetes and other diseases, and strengthened the analysis and research of biologically active substances in order to further clarify their efficacy. However, the results achieved were limited. This is mainly due to the complex pathogenesis of cardiovascular and cerebrovascular diseases, diabetes and other...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/65A61P3/10A61P25/28A61P9/00
Inventor 林艳和潘锡平林谷风
Owner YUNNAN BIOVALLEY PHARMA CO LTD
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