Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicinal formulation for treating cardiovascular and cerebrovascular disease

A technology of cardiovascular and cerebrovascular diseases and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine compositions for the treatment of cardiovascular and cerebrovascular diseases. It can solve the problems of being unable to take care of oneself, the burden of relatives and society, and achieve the effects of quality control, easy industrialization, and multiple benefits.

Inactive Publication Date: 2007-02-28
TIANJIN TASLY PHARMA CO LTD
View PDF2 Cites 11 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The percentage of deaths due to cardiovascular and cerebrovascular diseases in the total death population in my country has risen from 12.07% in 1957 to 42.6% in 2001, and 2 million people died of cardiovascular and cerebrovascular diseases every year, and some patients survived despite rescue. , but most of them are disabled and unable to take care of themselves, causing serious burden to relatives and society

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0100] Preparation of Danshensu extract: take Danshen decoction pieces, add water 5 times the weight of the crude drug, add 0.4% aqueous sodium bicarbonate solution to adjust the pH to 8, reflux extraction for 2 hours, and separate the extract; add 5 times the weight of the crude drug to the residue amount of water, reflux extraction for 2 hours, separate the extract, combine the two extracts, and filter; add 1.5% hydrochloric acid to the filtrate to adjust the pH of the solution to 2, filter or centrifuge, and concentrate the supernatant or filtrate under reduced pressure to a density of 1.08 (55-60°C); add 95% ethanol to the concentrated solution to make the alcohol concentration of the solution 50%, let it stand for 18 hours, filter, and concentrate the filtrate under reduced pressure until there is no alcohol smell; AB-8 type large Pore ​​resin (produced by Tianjin Nankai University Resin Factory) column, first wash away with water of 2 times the column volume, discard, the...

Embodiment 2

[0104] Preparation of Danshensu extract: take Danshen decoction pieces, crush them, add water 5 times the weight of the crude drug, add 0.35% sodium carbonate to adjust the pH to 9, extract by ultrasonic for 30 minutes, separate the extract; the residue is 5 times the weight of the crude drug amount of water, ultrasonic extraction for 20 minutes, separate the extract, combine the two extracts, and filter; add 2% acetic acid to the filtrate to adjust the pH of the solution to 2, filter or centrifuge, and concentrate the supernatant or filtrate under reduced pressure to a density of 1.06 (55-60°C); add 95% ethanol to the concentrated solution to make the alcohol concentration of the solution 40%, let it stand for 18 hours, filter, and concentrate the filtrate under reduced pressure until it has no alcohol smell; put D101 macroporous resin on the concentrated solution (produced by Resin Factory of Nankai University, Tianjin) column, wash off with water of 2 times column volume fir...

Embodiment 3

[0108] Preparation of Danshensu extract: take Danshen decoction pieces, crush them, add water 5 times the weight of the crude drug, add 0.35% sodium carbonate to adjust the pH value to 9, reflux extraction for 2 hours, separate the extract; the residue is 5 times the weight of the crude drug amount of water, reflux extraction for 1.5 hours, separate the extract, combine the two extracts, and filter; add 1% hydrochloric acid to the filtrate to adjust the pH of the solution to 2, filter or centrifuge, and concentrate the supernatant or filtrate under reduced pressure to a density of 1.06 (55-60°C); add 95% ethanol to the concentrated solution to make the alcohol concentration of the solution 65%, let it stand for 18 hours, filter, and concentrate the filtrate under reduced pressure to no alcohol smell; polyamide (Qingdao Haiyang Chemical Plant) column, collect the eluate; the eluate is then loaded on the ZTC type macroporous resin (produced by Tianjin Nankai University Resin Fact...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, which comprises 5.0-80.0% of danshensu extract containing danshensu 50-98%, 15.0-93.0% of pseudo-ginseng extract containing total notoginsen triterpenes 70-98%, and natural borneol or rosewood oil 2.0-15.0%. The composition has evident functions in resisting cerebral ischemia and myocardial ischemia, the curative effect is better than the application of single extract of red sage root or notoginseng, thus providing a more effective and more convenient Chinese medicinal composition and preparation clinically.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. Background technique [0002] According to my country's epidemiological survey, the incidence and mortality of cardiovascular and cerebrovascular diseases have been on the rise in the past 50 years, whether in rural areas or cities. In the 1950s and 1960s, cardiovascular disease and cerebrovascular disease ranked fifth and sixth among the causes of death in my country, and rose to second and third respectively after 1975. Cardiovascular and cerebrovascular diseases accounted for the first place among all causes of death. The percentage of deaths due to cardiovascular and cerebrovascular diseases in the total death population in my country has risen from 12.07% in 1957 to 42.6% in 2001, and 2 million people died of cardiovascular and cerebrovascular diseases every year, and some patients survived ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/537A61K9/14A61K9/20A61P9/00A61K31/045
Inventor 叶正良李旭张文生魏峰李德坤
Owner TIANJIN TASLY PHARMA CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com