21 results about "Substituted amide" patented technology

The present application provides a polymer, a battery cell, a manufacturing method therefor, a battery device, and an electric device. The polymer comprises a phenyl group, formula (I), a flexible chain segment, and an end group; the end group comprises one or more of a substituted or unsubstituted amide group and a substituted or unsubstituted -NH2, and optionally one or more of a carbonate group, a sulfonate group, a phosphate group, a quaternary ammonium group, and a C6-C18 aryl group; the flexible chain segment comprises one or more of -CH2-O-CH2- and -C(O)O-, and optionally -CH2-; the flexible chain segment is linked to -O- in formula (II); and the end group is linked to the flexible chain segment.

Provided is a method for producing a decomposing / cleaning composition which improves etching speed retention. In particular, a method for producing a decomposing / cleaning composition which contains (A) an N-substituted amide compound in which a hydrogen atom is not directly bonded to a nitrogen atom and (B) a quaternary alkyl ammonium fluoride or a hydrate thereof is provided, the method having a preparation step for mixing the (A) and (B) components in an inert gas atmosphere.

The invention belongs to the technical field of biological medicine, and particularly relates to an N-aryl substituted amide as a novel HDAC6 (histone deacetylase 6) inhibitor and application of the N-aryl substituted amide in preparation of antitumor drugs. A compound shown as a formula (I) is screened and synthesized on the basis of an artificial intelligence technology; the compound shows excellent inhibitory activity on HDAC6, and can be used for efficiently inhibiting HDAC6 and / or HDAC1; in addition, anti-tumor cell proliferation evaluation further reveals that the compound can significantly inhibit proliferation of tumor cells. Based on the excellent enzyme inhibition activity and the cellular level anti-proliferation effect, the compound can be used for preparing medicines for treating tumors, autoimmune diseases, inflammation or Alzheimer's disease, and has a wide development prospect.

An indeno-fused naphthopyran having the core skeletal structure (I): (I) wherein R1 is a substituted or unsubstituted alkyl group; R2 is substituted or unsubstituted amino; substituted or unsubstituted alkyl; substituted or unsubstituted alkenyl; substituted or unsubstituted alkynyl; substituted or unsubstituted aryl; substituted or unsubstituted heteroaryl; substituted or unsubstituted alkoxy; substituted or unsubstituted aryloxy; substituted or unsubstituted alkylthio; substituted or unsubstituted aryl thio; or substituted or unsubstituted amide, urea, and carbamate; and at least one of R3 and R4 is an electron donating group, wherein the sum of the Hammett σp values for R3 and R4 is less than −0.40, wherein when R1 is a substituted alkyl group, a carbon atom of the alkyl group is directly bonded to the 7-position carbon atom, and the carbon atom of the alkyl group that is directly bonded to the 7-position carbon atom is unsubstituted.

The invention relates to a benzenedicarboxamide compound as well as a preparation method and application thereof. The structure of the benzenedicarboxamide compound or the pharmaceutically acceptable salt thereof is shown as a general formula I, and R is selected from substituted or unsubstituted acylamino. Compared with the prior art, the phthalamide compound provided by the invention can specifically up-regulate secretion of IL-2 cell factors by remarkably enhancing a T cell lysosome function, so that a novel immune regulation strategy is provided. The synthesis route adopted by the invention has the advantages of cheap and easily available raw materials, simple route, common reagents, mild reaction conditions and simple post-treatment, and can be used for efficiently preparing the compounds.

The invention relates to a tetrahydrothebaine derivative as well as a preparation method and application thereof, in particular to a 7alpha-(4 '-substituted amidophenyl)-6alpha, 14alpha-endo-ethylidene (alkenyl)-tetrahydrothebaine derivative as shown in a general formula (I) or pharmaceutically acceptable salts thereof and a preparation method of the 7alpha-(4'-substituted amidophenyl)-6alpha, 14alpha-endo-ethylidene (alkenyl)-tetrahydrothebaine derivative. And to the use of such derivatives in the preparation of medicaments for the treatment and / or prevention of pain, irritable bowel syndrome, pruritus, addiction, depression. The derivative disclosed by the invention has a remarkable improvement effect in the aspects of agonistic activity of the kappa opioid receptor, subtype selectivity of the kappa opioid receptor and central safety.

The invention discloses a preparation method of a deuterated pyridinium salt participated photo-induced bicyclo [1.1. 1] pentane derivative, which comprises the following steps: putting a compound shown in a formula 1 and a compound shown in a formula 2 into an organic solvent, and carrying out illumination reaction on the compound shown in the formula 1 and the compound shown in the formula 2 and a bicyclo [1.1. 1] pentane compound shown in a formula 3 in an alkaline environment to obtain the deuterated pyridinium salt fragment-containing bicyclo [1.1. 1] pentane derivative shown in a formula 4, the reaction process is as follows: a substituent R1 is selected from an ester group or substituted amide, a substituent R2 is selected from phenyl or substituted phenyl, and the substituent of the substituted phenyl is methyl, methoxyl, cyano, an ester group, phenyl, halogen, tertiary butyl, phenoxyl, trifluoromethoxyl or trifluoromethyl. The method has the advantages of mild reaction conditions, no need of a catalyst, complete reaction at room temperature, economy, practicability, environmental friendliness and no generation of harmful substances; the efficiency is high after reaction amplification.

An N-substituted amide derivative inhibitor, its preparation method, and its application. In particular, it relates to N-substituted amide derivative compounds, their preparation methods, pharmaceutical compositions containing the compound, and their use in the treatment of cancer.

The application relates to a methionine probe and application thereof. The methionine probe has structural characteristics shown in the following formula (I): A-L-B (I), wherein A is a reporter group, L is a linking group, and B is a warhead group; the warhead group comprises a phenanthraquinone group; and the linking group comprises a substituted or unsubstituted amide group. The methionine probe has high labeling efficiency and is suitable for active motif spectrum analysis of a complex biological system.

polishing slurry including an abrasive, an oxidizing agent, and a first histidine derivative including a substituted or unsubstituted cyclic imide group, optionally a second histidine derivative including a substituted or unsubstituted amic acid group, or a combination thereof. A method of manufacturing a semiconductor device using the same is described.

This N-substituted amide having a bulky amide bond and having a group represented by general formula (3A) at least at one terminal thereof can be efficiently produced by reacting an acid chloride having a group represented by general formula (1A) at least at one terminal thereof with an N-substituted amino acid represented by general formula (2) in the presence of a tertiary amine having a pKaH of 10-17.

This N-substituted amide having a bulky amide bond and having a group represented by general formula (3A) at least at one terminal thereof can be efficiently produced by reacting an acid chloride having a group represented by general formula (1A) at least at one terminal thereof with an N-substituted amino acid represented by general formula (2) in the presence of a tertiary amine having a pKaH of 10-17.

A fluorescent dye according to formula (I), (II), (III), (IV), (V), (VI), (VII), (VIII), (IX), (X) and (XI): with R 1 selected from the group nitrile, nitro, formyl, carboxyl, substituted or unsubstituted C2-C 20 Acylalkyl, substituted or unsubstituted C5-C 20 Acylaryl, substituted or unsubstituted C2-C 20 Acyloxy, substituted or unsubstituted C2-C 20 Ester, substituted or unsubstituted C2-C 20 Amide with R 2 selected from the group hydrogen, nitrile, nitro, formyl, carboxyl, substituted or unsubstituted C2-C 20 Acylalkyl, substituted or unsubstituted C5-C 20 Acylaryl, substituted or unsubstituted C2-C 20 Acyloxy, substituted or unsubstituted C2-C 20 Ester, substituted or unsubstituted C2-C 20 Amide with R3 , R 4 , R 5 and R 6 independently selected from the group of substituted or unsubstituted C1-C 20 Alkyl, substituted or unsubstituted C2-C 20 Alkyl ethers and substituted or unsubstituted C6-C 20 Aryl; and with Z and X selected independently from a substituted or unsubstituted methylene or a substituted or unsubstituted ethane-1,2-diyl, where in formulas (I), (II), (III), (VI), (VII), (VIII), (IX) and (X) Z and X represent the substituted methylene and the substituted ethane-1,2-diyl with at least one substituted or unsubstituted C1-C 20 Alkyl and / or with a substituted or unsubstituted C2-C 20 Esters are substituted.

The application relates to the technical field of diacyl podioether synthesis, in particular to a diacyl podioether and a synthesis method thereof. The method takes 1,4-dioxane-2-ketone as a raw material, and an intermediate 2-(2-hydroxyethoxy) amide is obtained by ring-opening reaction of 1,4-dioxane-2-ketone and dialkylamine; then, another intermediate oxygen hetero-substituted amide is generated by oxidizing the hydroxyl group into a carboxyl group; finally, the oxygen hetero-substituted amide and the dialkylamine are condensed to prepare the diacyl podioether, the generation of intermediates such as acyl chloride and diethylene glycol anhydride is avoided, the synthesis route is simple to operate and easy to purify, the total yield is more than 61%, the method meets the increasing industrialization demand of the products, and lays a good foundation for batch production.

This invention discloses a non-aqueous electrolyte and a secondary battery comprising the non-aqueous electrolyte. The non-aqueous electrolyte of this invention comprises a lithium salt, a non-aqueous organic solvent, and an additive. The additive includes a first additive having the structure shown in Formula I, wherein M... + Selected from heterocyclic ononium cations containing tertiary amine nitrogen, aliphatic tertiary amine ononium cations, or N,N-dialkyl-substituted amide ononium cations, Q ‑ It contains fluorine-containing anionic groups. The non-aqueous electrolyte of this invention, due to the inclusion of ionic compounds with special structures, can effectively improve the electrochemical performance of secondary batteries, especially high-rate cycling performance and low-temperature discharge performance.

The present invention provides a composition which is suppressed in decrease of the etching rate over time. A composition which contains; at least one of a quaternary alkyl ammonium fluoride and a hydrate of a quaternary alkyl ammonium fluoride; (A) an N-substituted amide compound that has no active hydrogen on a nitrogen atom and (B) a dipropylene glycol dimethyl ether, which serve as aprotic solvents; and an antioxidant.

The application discloses an extraction solvent and an extraction method for stepwise recovery of vanadium and chromium in a solution by steric hindrance effect of an amide extractant, wherein the extraction solvent is composed of extraction solvent A and extraction solvent B; the extraction solvent A is composed of a large steric hindrance amide extractant and diluent A; the extraction solvent B is composed of a small steric hindrance amide extractant and diluent B; the large steric hindrance amide extractant and the small steric hindrance amide extractant are both alkyl-substituted amide extractants; and the diluent A and the diluent B are both inert organic solvents. The steric hindrance effect of the amide extractant in the extraction solvent is utilized to stepwise recover vanadium and chromium in the solution, and high-purity chromium-containing stripping liquid and vanadium-containing stripping liquid are obtained, which has the advantages of high extraction rate, high separation coefficient, high product purity, fast extraction kinetics, good regeneration of the extraction solvent and green harmlessness.

The application provides a cathode electrophoretic paint as well as a preparation method and application thereof. The cathode electrophoretic paint comprises a modified polyimide polymer, a blocked isocyanate, an acid, an organic solvent and water; at least one end of the modified polyimide polymer is a polyimide molecular chain, and the end of the polyimide molecular chain has a hydroxyalkyl-substituted amide group. The cathode electrophoretic paint has good high-temperature resistance, and the formed electrophoretic coating has high density and good thermal stability, which is beneficial to long-term and effective protection of the coating to metal workpieces.

The invention provides a polymer, a battery monomer, a manufacturing method thereof, a battery device and a power utilization device. The polymer comprises phenyl, flexible chain segments and end groups, and the end groups comprise one or more of substituted or unsubstituted amide groups and substituted or unsubstituted-NH2 and one or more of optional carbonic ester groups, sulfonate groups, phosphate groups, quaternary ammonium groups and C6-C18 aryl groups. The flexible chain segment comprises one or more of-CH2-O-CH2-and-C (O) O-and optional-CH2-, the flexible chain segment is connected to-O-in the flexible chain segment, and the end group is connected to the flexible chain segment.

The embodiment of the invention discloses a fluorophenyl ether derivative containing trifluoromethyl as well as a preparation method and application thereof, and belongs to the technical field of pesticides. The phenyl ether derivative containing trifluoromethyl has a structure as shown in a general formula (I), in the general formula (I), A is S or S = O, X is halogen, R is hydrogen, alkyl or halogen substituted thiazolyl, alkyl or aryl substituted acylamino, and n is 0, 1, 2 or 3. The phenyl ether derivative containing trifluoromethyl provided by the invention has better anti-mite activity. The synthesis method provided by the invention is simple, the raw materials are cheap and easy to obtain, and a novel anti-mite pesticide is expected to be developed. (I).