52results about How to "Appropriate consistency" patented technology

Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

A polypeptide self-antigen useful in a tumor-specific vaccine mimics one or more epitopes of an antigen uniquely expressed by cells of the tumor. The polypeptide is preferably produced in a plant that has been transformed or transfected with nucleic acid encoding the polypeptide and is obtainable from the plant in correctly folded, preferably soluble form without a need for denaturation and renaturation. This plant-produced polypeptide is immunogenic without a need for exogenous adjuvants or other immunostimulatory materials. The polypeptide is preferably an scFv molecule that bears the idiotype of the surface immunoglobulin of a non-Hodgkin's (or B cell) lymphoma. Upon administration to a subject with lymphoma, the plant-produced, tumor-unique scFv polypeptide induces an idiotype-specific antibody or cell-mediated immune response against the lymphoma.

An emulsion cosmetic composition comprising at least one resveratrol derivative, an aqueous phase, and an oil phase having at and at least one oil phase structuring agent, and a method for preparing emulsions capable of delivering active resveratrol to the skin.

This invention provides a method for using a polymer thick film copper conductor composition to form an electrical conductor in an electrical circuit, the method subjecting the deposited thick film copper conductor composition to photonic sintering. The invention also provides a method for reducing the resistance of an electrical conductor formed from a polymer thick film conductor composition, the method comprising the step of subjecting the electrical conductor to photonic sintering. The invention further provides devices containing electrical conductors made by these methods. The invention also provides a polymer thick film copper conductor composition.

Deodorant or antiperspirant sticks based on an oil-in-water dispersion / emulsion for application on the skin.

The invention contains a water soluble block copolymer and a reverse thermo-sensitivity reversible aquogel composite including at least one correlation gel adjuvant. The water soluble block copolymer contains at least two polyethylene oxide blocks and a polypropylene oxide block. The solubility of the correlation gel adjuvant in water is less than 0.5g / 100ml and a better choice is less than 0.3g / 100ml. The correlation gel adjuvant is able to form water soluble intermolecular complex with water soluble block copolymer. The aquogel composite shows improved gel efficiency and improvement for solubility and / or stability of slightly water soluble and / or water insoluble reagent. The aquogel composite can be applied to various medicine and cosmetic products, such as treatment for esophagus, ear, vagina, rectum, eye and skin diseases and defects.

A method and compound for the treatment of disease involving hyperproliferation of dermis cells is provided. In particular, compounds isolated from the species of plants known as calendula have been found to be beneficial in the treatment of psoriasis. An extract of plant material obtained from calendula officinalis has been found to be advantageous as an active compound in medicaments for use in the treatment of psoriasis.

The invention discloses water-soluble supramolecular complexes. The water-soluble supramolecular complexes are formed from a water soluble block copolymer and at least one associative gelling adjuvant. The copolymer includes at least two blocks of polyethylene oxide and at least one block of polypropylene oxide. The adjuvant has a water solubility less than 0.5 g / 100ml at 20 DEG C. When combined with water, the complexes form a transparent reversely thermo-reversible hydrogel or solution that may be repeatedly hydrated and dehydrated. The hydrogel exhibits improved gelling efficiency and enhanced solubility and / or stability for sparely soluble and insoluble pharmaceutical agents. The complexes are useful in a variety of pharmaceutical and cosmetic products and applications and may be combined with an effective amount of a cosmetic, medicament, or diagnostic in a solid dosage form.

Disclosed is an electroconductive grease comprising a fluorine oil, an electroconductive material, and a thickening agent, the electroconductive grease containing 5 to 20 wt. % of carbon black having a DBP oil absorption amount of 250 ml / 100 g or less as the electroconductive material, and 2 to 15 wt. % of fluorine-containing resin particles having an average primary particle size of 1.0 μm or less as the thickening agent. The electroconductive grease comprises carbon black having specific properties, and fluorine-containing resin particles, preferably PTFE particles, having an average primary particle size of 1.0 μm or less, and therefore exhibits excellent oil separation characteristics, namely, a remarkably lower degree of oil separation, which can also be reduced to 10 wt. % or less.

Deodorant or antiperspirant sticks based on an ethanol-containing oil-in-water dispersion / emulsion for application on the skin.

The total matrine gel preparation contains total matrine in 3-5 wt% and Carbocromen in 0.5-1.5 wt%. The present invention also provides the preparation of the gel preparation including the steps of extracting total matrine with type-110 cationic exchange resin; forming gel with Carbocromen as adjuvant; dissolving total matrine in ethanol and propylene glycol to form solution and adding the solution into the gel to form the total matrine gel preparation. The gel preparation has the advantages of powerful adhesional force to mucous membrane and thus prolonged detention time in vagina and raised curative effect.

The invention provides an amino acid type facial cleanser which is prepared from the following raw materials in percentage by weight: 10 to 30 percent of amino acid surfactant, 0.5 to 2 percent of thickener, 0.2 to 2.5 percent of neutralizer, 0.1 to 1 percent of conditioner and deionized water. The invention also provides a preparation method of the amino acid type facial cleanser. The preparation method comprises the steps of firstly, thinning the thickener, adding the amino acid surfactant, stirring, dissolving, adding the conditioner and the like, and standing for one night, so as to obtain the amino acid type facial cleanser. The amino acid type facial cleanser provided by the invention is neutral, mild and skin-friendly, safe and non-irritant without adding burden to skin, capable of deeply cleaning the skin, and suitable for any skin and can be used for a long term, and after the skin is cleaned by using the cleanser, the skin can quickly return to oil-water balance and acid-base balance; the texture of the cleanser is emulsion appearance, and the cleanser has excellent appearance and moisture retention, excellent in high and low temperature stability, has a certain thickness and can provide good user using experience.

Deodorant or antiperspirant sticks based on an oil-in-water dispersion / emulsion for application on the skin.

The invention discloses a method for manufacturing jam by skin and pulp as well as sac juice of a seed melon without seeds. The method has the following technical effects that melon skin and pulp as well as sac juice of the seed melon without the seeds can be sufficiently utilized to manufacture seed melon jam with a special seed melon flavor; the appearance of the manufactured seed melon jam is yellow, the color is uniform and consistent and the jam has luster; the thickness of the jam body is suitable, grains are fine and smooth and are uniformly distributed, the jam does not disperse, no obvious bleeding and layering exist and no sugar is crystallized; on the aspects of the taste and the flavor, the taste is fine and smooth; the sourness and sweetness are moderate; the jam has the faint scent of the seed melon and has the flavor of the jam; a physicochemical index and a microorganism and food safety standard completely accord with relevant national standards of the jam; a seed melon resource can be sufficiently utilized and the economic benefit of the seed melon seed machining enterprise can be greatly increased; and the environmental pollution is eliminated and a market food supply is enriched.

The invention relates to an oxybutynin chloride externally-applied preparation for treating overactive bladder, and a preparation method thereof. The oxybutynin chloride externally-applied preparation is prepared by an oxybutynin chloride particle intermediate and pharmaceutical preparation adjuvants, wherein the oxybutynin chloride particle intermediate comprises 0.1%-10% of oxybutynin, 10%-50% of an oil phase, 1%-20% of a surface-active agent and 20%-70% of a propping agent. The oxybutynin chloride externally-applied preparation can greatly increase stability of the preparation, is beneficial to long-term storage of the drug, prevents the situations of applying a lot of the surface-active agent for increasing the solubility and stability of a liquid emulsion, and is beneficial to reduce stimulation of the preparation to skins. Beside, for a single dose dry emulsion, water-adding proportions can be adjusted by a patient in a certain range, and proper viscosity and thickness can be obtained, thereby facilitating increasing compliance of the patient.

A product based on conjugated linoleic acid (CLA) comprises an inner core in which the conjugated linoleic acid is substantially concentrated as well as a coating for covering and protecting the inner core; the coating in turn comprises a fraction greater than 80% by weight relative to the coating of a lipid matrix formed by glycerides of C16, C18, C20 and C22 saturated fatty acids.

The present invention relates to a thick film conductor composition comprising: (a) electrically conductive silver powder; (b) PVDF / HFP polymer resin, copolymers of a PVDF / HFP polymer resin, and mixtures thereof; dissolved in (c) organic solvent, with the provisos that the PVDF / HFP resin has a melt viscosity of 0.2-0.7 kPoise and a DSC melt temperature in the range of 85-98° C.

A database management system for determining consistency in a hierarchical database sequentially reads pointers of a plurality of segment data, generates an address hash value, which is a hash value of retention addresses of the segment data having been read, generates a pointer hash value, which is a hash value of the pointers included in the segment data having been read, corrects the address hash value, when the contents of the address already read is updated, based a retention address of segment data added or deleted by the update, corrects the pointer hash value based on each pointer changed by the update, and determines that the hierarchical database is consistent if the corrected address hash value coincides with the corrected pointer hash value.

The invention provides toothpaste and a preparation method thereof, and relates to the technical field of cleaning supplies. The toothpaste includes the following components in parts by weight: 0.1-3parts of a tooth protection agent, 15-65 parts of a moisturizer, 1-5 parts of a cleaning agent, 5-15 parts of a friction agent, 2-10 parts of a sweetener, 0.5-5 parts of a thickener, 0.1-4 parts of astabilizer, 0.1-5 parts of an enzyme preparation and 0.2-5 parts of a cooling agent. The toothpaste provided by the invention uses the moisturizer, the cleaning agent, the friction agent and the sweetener as main raw materials supplemented by the tooth protection agent, the thickener, the stabilizer, the enzyme preparation and the cooling agent, is prepared by using green and environment-friendlyraw materials, and is safe and health. The toothpaste prepared by using the above raw materials can protect the health of teeth, and the taste and quality of the toothpaste can be enhanced and improved, so that a user has better experience feeling.

The invention belongs to the technical field of toothpaste, and particularly relates to toothpaste containing bioactive glass components and a preparation method of the toothpaste. The toothpaste comprises the following raw materials: bioactive glass, an abrasive, a solubilizer, a moisturizer, a surfactant, a sweetening agent and a preservative. By using the bioactive glass, the toothpaste not only has the traditional effects of resisting allergy, preventing tooth decay, strengthening and whitening teeth, stopping bleeding, diminishing inflammation, removing peculiar smell and the like, but also has the effects of repairing shallow pits and solving the problem of dental ulcer, the abrasive in the toothpaste can act together with a toothbrush to wipe tartar on the surfaces of the teeth andreduce solid raw material components of foreign substances such as tooth stains, dental plaque, dental calculus and the like, and a thickening agent can enable the toothpaste to have proper viscosityand consistence and enable the toothpaste not to be sticky or greasy; the toothpaste is provided with a framework, so that the extruded toothpaste can stay on the toothbrush without collapsing; duringtooth brushing, the toothpaste is easy to disperse and has good diffusion performance; and moreover, the paste is fine and glossy, and the abrasive is uniformly dispersed and does not get sticky or become coarse.

The invention relates to a geriatric feeding cup for feeding liquid to an elderly person, including a cup adapted to receive the liquid, a lid and a spout made of a soft pliable material fitted to the cup. In use, the geriatric feeding cup enables the search reflex, the suck reflex and the swallow reflex to be stimulated in the elderly person so that they can be fed the liquid in a more effective and safe manner. The invention also relates to a method of use of the geriatric feeding cup whereby the search reflex, the suck reflex and the swallow reflex are stimulated to feed the person.

The invention provides a fermented milk, such as soft yogurt, that has appropriate viscosity and body and is free from roughness in palatability and in appearance, and provide a process for producing the same. There is provided a process for producing a fermented milk of 10 to 20 [mu]m average particle diameter and = 8000 mPa s viscosity, and provided a process for producing a fermented milk of 10 to 20 [mu]m average particle diameter and = 8000 mPa s viscosity wherein no stabilizer is added or a minute amount of stabilizer is added. There are provided, produced by these processes, a fermented milk of 10 to 20 [mu]m average particle diameter and = 8000 mPa s viscosity and a fermented milk of 10 to 20 [mu]m average particle diameter and = 8000 mPa s viscosity wherein no stabilizer is added or a minute amount of stabilizer is added.

A database management system for determining consistency in a hierarchical database sequentially reads pointers of a plurality of segment data, generates an address hash value, which is a hash value of retention addresses of the segment data having been read, generates a pointer hash value, which is a hash value of the pointers included in the segment data having been read, corrects the address hash value, when the contents of the address already read is updated, based a retention address of segment data added or deleted by the update, corrects the pointer hash value based on each pointer changed by the update, and determines that the hierarchical database is consistent if the corrected address hash value coincides with the corrected pointer hash value.

A powdered material, the binder phase of which consisting of a cement-based system that has the capacity following saturation with a liquid reacting with the binder phase to hydrate to a chemically bonded ceramic material. According to the invention, the powdered material exists in the form of granules of powder particles, which granules exhibit a degree of compaction above 55% and a mean size of 30-250 μm. The invention also relates to a raw compact of the powdered material and a method in connection with the manufacturing of a ceramic material from a powdered material. The invention also relates to a device for the powdered material.

Use of stereoisomeric glycosidic compounds of formula (I) as pharmaceutical agents against psoriasis, compounds therefor and pharmaceutical formulations thereof wherein R1 and R2 are independently selected from -H, -OH, (1) and (2) and related esters and ethers thereto; R3 is selected from -H, (3), (4), (5), (6), (7) and (8) and related esters and ethers thereto; R4 is (9); R5 is selected from the group -CH3, -CHO, -COOH, -CH2OH and related esters and ethers thereto; R6 is selected from -OH, (10), (11), (12), (13) and (14) in the preparation of a medicament for the treatment of disease involving hyperproliferation of dermis cells.

The present invention relates to a composition comprising Lactobacillus rhamnosus GG (LGG) (ATCC 53103) and / or a bioactive extract of LGG to increase the expression of filaggrin or profilaggrin, for use in treating skin or mucosa barrier dysfunctions or defects. The present invention also comprises the use of a composition comprising Lactobacillus rhamnosus GG (LGG) (ATCC 53103) and / or a bioactive extract of LGG to increase the expression of filaggrin or profilaggrin, for use in the manufacture of a medicament for use in treating skin barrier dysfunctions. Also disclosed is a use of a composition comprising Lactobacillus rhamnosus GG (LGG) (ATCC 53103) and / or a bioactive extract of LGG to increase the expression of filaggrin or profilaggrin, for use in the manufacture of a cosmetic composition for use in improving the appearance and / or texture of the skin. The present invention also comprises a method of treating skin barrier dysfunctions comprising administering a composition comprising Lactobacillus rhamnosus GG (LGG) and / or a bioactive extract of LGG to increase the expression of filaggrin or profilaggrin.

The invention pertains to the field of medical technology, which relates to a bifonazole emulgel and the preparation method. The prescription composition of the emulgel is that: 0.5 percent to 2 percent bifonazole, 5 percent to 15 percent oil phase, 65 percent to 90 percent water phase, 2 percent to 10 percent emulsifier and 0.5 percent to 10 percent gel matrix, the preparation method of the bifonazole emulgel is that: the bifonazole is firstly prepared into the emulsion and then is dispersed in the gel matrix, the obtained preparation for external use is the milky white colloidal semi-solid, which is even, fine, appropriate in thickness, rich in luster and better in coating. The preparation method of the invention is more convenient, economical and more easy for industrial production, and the prepared bifonazole emulgel has good stability.