Interventional infusion device for shutting tumor tissue blood supply

Abstract

The invention discloses an interventional infusion device for shutting tumor tissue blood supply, which comprises an injection part, and an injection speed control assembly is arranged on the surface of the bottom of the outer ring of the injection part; the injection part comprises a needle cylinder, a needle nozzle fixed at the front end of the needle cylinder and an infusion catheter connected to a front port of the needle nozzle, a piston is movably arranged in an inner cavity of the needle cylinder, and the rear end of the piston is connected with a push rod penetrating to the rear side of the needle cylinder. According to the technical scheme, the injection speed control assembly is arranged between the needle cylinder and the push rod of the injector, the servo motor is used for driving the gear, and the gear is meshed to drive the rack to move, so that the rack moves to pull the push rod to slowly push the medicament in the needle cylinder at a constant speed, and the problem that the medicament needs to be manually pushed for a long time is solved; and moreover, the stability of the medicament injection speed is improved, the injection speed is controllable, and discomfort caused by too fast injection of a patient is avoided.

Description

Technical Field

[0001] The present invention relates to the technical field of tumor interventional infusion instruments, and in particular to an interventional infusion device for blocking the blood supply of tumor tissue. Background Art

[0002] With the continuous development of medical technology, interventional treatment of tumors has gradually become an important treatment method. Among these technologies, transcatheter arterial infusion chemotherapy (TAI) is a minimally invasive treatment method that is widely used in the treatment of various solid tumors. This technology directly delivers high-concentration chemotherapy drugs to the tumor blood supply artery through a catheter, thereby maximizing the concentration of drugs in the local tumor, achieving a "first-pass effect", enhancing the anti-tumor effect of chemotherapy drugs, and reducing toxic side effects on normal tissues.

[0003] At present, traditional interventional infusion devices mainly rely on manual operation to push the drug into the catheter through the syringe and deliver it to the tumor tissue. In clinical practice, in order to ensure the safety of patients and the treatment effect, the speed of drug injection must be slow and uniform. Too fast drug injection may cause fluctuations in the patient's hemodynamics and injection-related discomfort symptoms; while too slow drug injection may affect the treatment efficiency and prolong the operation time. Therefore, the operating physician usually needs to manually push the syringe at a uniform speed for a long time. This operation method places high demands on the physician's endurance and hand feel, and is easily interfered by human factors, resulting in uneven drug injection speed. In addition, since the displacement of the syringe push rod is proportional to the injection amount of the drug, in actual operation, the physician needs to rely on experience to control the drug delivery amount and speed, and lacks a unified quantitative standard, which further increases the difficulty of operation.

[0004] In order to overcome the limitations of manual injection, some interventional infusion devices have introduced mechanically assisted designs, such as using electric injection pumps to achieve uniform drug delivery. However, existing electric injection pumps are large in size, complex in structure, and cumbersome to operate, making them unsuitable for flexible use in space-constrained surgical environments. In addition, due to the limited accuracy and stability of existing electric injection devices, they may be affected by factors such as motor vibration and mechanical errors during the infusion process, resulting in fluctuations in drug injection speed and pressure, which in turn affects the patient's treatment effect and comfort.

[0005] To address this problem, the present invention proposes an interventional infusion device for blocking the blood supply to tumor tissue, aiming to provide a semi-automatic device with a compact structure, convenient operation and controllable injection process, so as to address the deficiencies in the prior art. Summary of the invention

[0006] The purpose of the present invention is to provide a technical solution for an interventional infusion device for blocking the blood supply of tumor tissue to solve the shortcomings mentioned in the background technology. In order to solve the disadvantages and defects mentioned in the background technology, the present technical solution has the following contents:

[0007] The device comprises an injection piece, the bottom surface of the outer ring of which is provided with an injection speed control component; the injection piece comprises a syringe, a needle nozzle fixed at the front end of the syringe, and an infusion catheter connected to the front end of the needle nozzle, a piston is movably arranged in the inner cavity of the syringe, and the rear end of the piston is connected to a push rod penetrating the rear side of the syringe;

[0008] The injection speed control assembly includes two columns, a clamp fixed on the upper end of the column and fixedly connected to the outer ring surface of the syringe, and a collar fixed on the rear side surface of the outer ring of the push rod, a connecting block is fixedly connected to the right side wall of the clamp on the front side, and a connecting rod is fixedly connected to the right side wall of the collar;

[0009] The front end face of the connecting rod is fixedly connected with a rack that passes through the connecting block, a servo motor is installed on the rear side wall of the connecting block, and the output shaft of the servo motor is connected with a gear meshing with the left tooth surface of the rack through a coupling.

[0010] As a preferred solution of the present invention: a rear section of the outer ring surface of the syringe is provided with a thread, and a syringe end cap is provided at the rear end port of the syringe by screwing the thread.

[0011] As a preferred solution of the present invention: the inner cavity of the syringe is filled with medicine required for interventional infusion, and the end of the infusion catheter away from the needle mouth is inserted into the femoral artery of the human body.

[0012] As a preferred solution of the present invention: the outer ring surface of the piston is in close contact with the inner cavity side wall of the syringe, and a through hole for the push rod to penetrate and move is opened at the inner center position of the syringe end cover.

[0013] As a preferred solution of the present invention: the axis of the connecting block and the axis of the connecting rod are coaxially arranged.

[0014] As a preferred solution of the present invention: a circular hole for the rack to pass through is provided inside the connecting block.

[0015] As a preferred solution of the present invention: a protrusion is fixedly connected to the rear end surface of the connecting block, and the side wall of the housing of the servo motor is fixedly connected to the rear end of the protrusion.

[0016] As a preferred solution of the present invention: a rectangular frame is fixedly connected to the bottom end surface of the column, and a layer of rubber pad is fixedly connected to the bottom end surface of the rectangular frame via an adhesive.

[0017] As a preferred solution of the present invention, the meshing between the servo motor and the gear adopts a gear set design with an adjustable speed ratio so as to adjust the injection speed according to the viscosity of the medicine.

[0018] As a preferred solution of the present invention: the inner wall of the infusion catheter is coated with an anti-adhesion coating to reduce the amount of drug residue on the inner wall of the catheter, thereby improving the drug delivery efficiency; a detachable connection structure is provided between the column and the rectangular frame to facilitate convenient maintenance and cleaning of the equipment.

[0019] In the above technical solution, the technical effects and advantages provided by the present invention are:

[0020] In this technical solution, an injection speed control component is arranged between the syringe barrel and the push rod of the syringe, and a servo motor is used to drive the gear. The gear meshing drives the rack to move, so that the movement of the rack pulls the push rod to push the medicine in the syringe at a uniform and slow speed, thereby avoiding the problem of manually pushing the medicine for a long time, and improving the stability of the medicine injection speed, making the injection speed controllable, and avoiding the patient's discomfort caused by too fast injection.

[0021] This device connects the servo motor to the syringe push rod and uses the meshing action of the gear and rack to achieve precise control of the push rod, thereby ensuring that the medicine is slowly and evenly advanced during the infusion process. At the same time, the device is equipped with an injection speed control component, which flexibly controls the infusion speed of the medicine by adjusting the speed of the servo motor to meet the needs of different patients and treatment plans. In addition, the design of this device fully considers the limitations of the clinical environment, adopts a lightweight and modular structure, is easy to carry and maintain, and greatly improves the practicality and reliability of the equipment.

[0022] Through this design, the present invention can significantly improve the efficiency and stability of the drug infusion process, reduce the operating burden of physicians, reduce the discomfort of patients during treatment, and provide more accurate drug dosage control, thereby improving the overall effect of interventional treatment. Compared with traditional manual operation methods and existing electric injection pumps, this device has significant advantages in volume, accuracy and ease of operation, and is an important technological advancement in the field of tumor interventional treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0024] Figure 1 It is the overall schematic diagram of the interventional infusion set;

[0025] Figure 2 is a schematic diagram of an injection part;

[0026] Figure 3 Schematic diagram of the injection speed control component.

[0027] Description of reference numerals:

[0028] 1. Injection parts; 11. Syringe; 12. Needle nozzle; 13. Infusion catheter; 14. Piston; 15. Syringe end cover; 16. Push rod; 2. Injection speed control assembly; 21. Rectangular frame; 22. Gear; 23. Connecting block; 24. Servo motor; 25. Column; 26. Clamp; 27. Rack; 28. Connecting rod; 29. ​​Ring. DETAILED DESCRIPTION

[0029] In order to more clearly explain and illustrate the technical solution and implementation of the present invention, several preferred specific embodiments for implementing the technical solution of the present invention are introduced below.

[0030] The following description is merely exemplary in nature and is not intended to limit the present disclosure, application, and use. It should be understood that in all of these figures, the same or similar figure numbers indicate the same or similar parts and features. The various figures only schematically represent the concepts and principles of the embodiments of the present disclosure, and do not necessarily show the specific dimensions and proportions of the various embodiments of the present disclosure. Specific parts in specific drawings may use exaggerated methods to illustrate the relevant details or structures of the embodiments of the present disclosure. The various publications, patents, and published patent specifications cited herein are incorporated herein by reference in their entirety. The technical solutions of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention.

[0031] Example 1, a preferred technical solution of an interventional infusion device for blocking the blood supply to tumor tissue, includes the following:

[0032] It comprises an injection piece 1, and an injection speed control component 2 is arranged on the bottom surface of the outer ring of the injection piece 1;

[0033] The injection device 1 includes a syringe 11, a needle nozzle 12 fixed to the front end of the syringe 11, and an infusion catheter 13 connected to the front end of the needle nozzle 12. A piston 14 is movably arranged in the inner cavity of the syringe 11, and a push rod 16 penetrating to the rear side of the syringe 11 is connected to the rear end of the piston 14.

[0034] The injection speed control assembly 2 includes two columns 25, a clamp 26 fixed to the upper end of the column 25 and fixedly connected to the outer ring surface of the syringe 11, and a collar 29 fixed to the rear side surface of the outer ring of the push rod 16, a connecting block 23 is fixedly connected to the right side wall of the front clamp 26, and a connecting rod 28 is fixedly connected to the right side wall of the collar 29;

[0035] The front end face of the connecting rod 28 is fixedly connected with a rack 27 that passes through the connecting block 23. A servo motor 24 is installed on the rear side wall of the connecting block 23. The output shaft of the servo motor 24 is connected to a gear 22 that meshes with the left tooth surface of the rack 27 through a coupling.

[0036] The rear section of the outer ring surface of the syringe 11 is provided with a thread, and the rear end port of the syringe 11 is provided with a syringe end cover 15 by screwing the thread. The inner cavity of the syringe 11 is filled with medicine required for interventional infusion, and the end of the infusion catheter 13 away from the needle mouth 12 is inserted into the femoral artery of the human body; the outer ring surface of the piston 14 is in close contact with the inner cavity side wall of the syringe 11, and the inner center position of the syringe end cover 15 is provided with a through hole for the push rod 16 to penetrate and move.

[0037] The axis of the connecting block 23 and the axis of the connecting rod 28 are coaxially arranged; a circular hole for the rack 27 to pass through is opened inside the connecting block 23, a protrusion is fixedly connected to the rear end face of the connecting block 23, the side wall of the shell of the servo motor 24 is fixedly connected to the rear end of the protrusion, the bottom end face of the column 25 is fixedly connected to the rectangular frame 21, and the bottom end face of the rectangular frame 21 is fixedly connected to a layer of rubber pad by an adhesive.

[0038] According to the above-mentioned preferred technical solution, the workflow of the technical solution is described as follows:

[0039] After the syringe 11 is filled with the medicine to be infused, the needle nozzle 12 is connected to the infusion catheter 13, and the servo motor 24 is controlled by the battery and controller suspended and fixed under the connecting block 23. The output shaft of the servo motor 24 drives the gear 22 to rotate, so that with the help of the meshing relationship between the gear 22 and the rack 27, the rack 27 is driven to pass through the connecting block 23 at a slow and uniform speed, and the connecting rod 28 and the ring 29 are pulled to move to the front side, thereby driving the push rod 16 to push into the syringe 11, and the piston 14 infuses the medicine from the syringe 11 into the infusion catheter 13, thereby achieving the effect of semi-automatic uniform infusion.

[0040] Embodiment 2:

[0041] In a specific application scenario, this embodiment provides an interventional infusion device for blocking the blood supply of tumor tissue suitable for transcatheter arterial chemoembolization (TACE) treatment of liver cancer patients.

[0042] The device comprises an injection part 1 and an injection speed control component 2. The injection part 1 is composed of a syringe 11, a needle mouth 12, an infusion catheter 13, a piston 14 and a push rod 16. The inner cavity of the syringe 11 is pre-filled with a mixed liquid of a chemotherapy drug and a microsphere embolic agent (for example, a mixture of doxorubicin and polyvinyl alcohol particles). One end of the infusion catheter 13 is fixedly connected to the front end of the syringe 11 through the needle mouth 12, and the other end is directly inserted into the blood supply branch of the patient's hepatic artery.

[0043] The injection speed control assembly 2 is mainly composed of a servo motor 24, a gear 22, a rack 27, a connecting rod 28 and a collar 29. The servo motor 24 converts the rotational motion of the motor into linear motion through the meshing action of the gear 22 and the rack 27, thereby driving the rack 27 to drive the push rod 16 to smoothly advance into the syringe 11. In order to achieve accurate drug infusion, the servo motor 24 accurately adjusts the speed and stroke through an embedded control system. The drug infusion rate (for example, a propulsion volume of 2 ml per minute) is preset in the control system to ensure that the drug and embolic agent can be evenly and slowly delivered to the target area.

[0044] In this embodiment, in order to improve the applicability of the device, the outer surface of the syringe 11 is provided with a scale mark for real-time display of the remaining amount of the medicine. At the same time, the bottom end of the column 25 is connected to a rectangular frame 21, and an adjustable rubber pad is installed at the bottom of the frame 21 to meet the fixing requirements of different operating tables.

[0045] In actual operation, the doctor first fills the syringe 11 with the medicine and inserts it into the blood supply branch of the hepatic artery through the infusion catheter 13. Then, the operating parameters of the servo motor 24 (including the injection speed and the total injection volume) are set using the controller. When the device is started, the servo motor 24 rotates at a set speed, and drives the push rod 16 to slowly advance the medicine through the gear 22 and rack 27 system. During the whole process, the medicine enters the blood supply branch of the hepatic artery at a stable speed and is evenly distributed in the tumor tissue. At the same time, the microsphere embolic agent effectively blocks the blood supply of the tumor to achieve a therapeutic effect.

[0046] Compared with the traditional manual push injection method, this device can significantly improve the accuracy and stability of drug infusion and reduce the discomfort caused by uneven push speed. In addition, doctors do not need to manually push drugs for a long time, thereby reducing the operating burden and improving treatment efficiency.

[0047] Embodiment 3:

[0048] This embodiment provides an interventional infusion device for blocking tumor tissue blood supply for adjuvant chemotherapy in patients with advanced tumors, which optimizes the accuracy and safety of the drug infusion process and is particularly suitable for clinical scenarios that require long-term slow infusion of drugs.

[0049] The device comprises an injection part 1 and an injection speed control component 2. The injection part 1 is composed of a syringe 11, a needle mouth 12, an infusion catheter 13, a piston 14 and a push rod 16. The inside of the syringe 11 is pre-filled with a chemotherapy drug with an anti-cancer effect (such as a paclitaxel solution). The distal end of the infusion catheter 13 is inserted into the patient's tumor supply artery (such as a gastric artery) through puncture. To ensure the sterility of the infusion process, the outside of the infusion catheter 13 is covered with a protective sleeve.

[0050] The injection speed control assembly 2 is composed of a servo motor 24, a gear 22, a rack 27, a connecting rod 28, a collar 29 and a pressure sensor. In this embodiment, the injection speed control assembly 2 is added with a pressure sensor module for real-time monitoring of the pressure changes of the drug during the infusion process. The pressure sensor is installed at the proximal end of the infusion catheter 13 and is connected to the control system via a wireless signal. When the pressure exceeds a set threshold (for example, 3 atmospheres), the control system will automatically slow down the speed of the servo motor 24 and reduce the propulsion speed of the push rod 16 to prevent the drug from being injected too quickly, causing discomfort to the patient or arterial damage.

[0051] In addition, to further enhance the convenience of operation, an adjustable display screen is integrated on the column 25 to display the infusion speed, remaining drug volume and infusion time in real time. The physician can quickly adjust the operating parameters of the servo motor 24 through the touch screen according to the patient's treatment needs. The power system of the device uses a rechargeable lithium battery, which can run continuously for 8 hours on a single charge, and is suitable for long-term infusion therapy.

[0052] During the operation, the physician first sets the drug infusion parameters, including the target pressure, infusion rate (e.g., 1 ml per minute) and total infusion time (e.g., 60 minutes), through the injection speed control component 2. After the servo motor 24 is started, the push rod 16 is slowly pushed forward through the meshing action of the gear 22 and the rack 27, so that the piston 14 evenly delivers the drug from the syringe 11 to the tumor supply artery. At the same time, the pressure sensor will continuously monitor the pressure changes during the infusion process to ensure that the entire operation is completed within a safe range.

[0053] The closed tumor tissue blood supply interventional infusion device of this embodiment not only improves the safety of the drug infusion process, but also reduces the complexity of clinical operations by introducing pressure monitoring and automatic adjustment functions. Compared with traditional devices, this solution can more accurately control the drug infusion speed, reduce the operating burden of physicians, and enhance the comfort and sense of security of patients during treatment.

[0054] The above description is only by way of illustration of certain exemplary embodiments of the present invention. It is undoubted that those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. An interventional infusion device for blocking blood supply to tumor tissue, comprising an injection device (1), characterized in that: An injection speed control component (2) is provided on the bottom surface of the outer ring of the injection component (1); The injection piece (1) comprises a syringe (11), a needle nozzle (12) fixed at the front end of the syringe (11), and an infusion catheter (13) connected to the front end of the needle nozzle (12); a piston (14) is movably arranged in the inner cavity of the syringe (11), and the rear end of the piston (14) is connected to a push rod (16) penetrating the rear side of the syringe (11); The injection speed control assembly (2) comprises two columns (25), a clamp (26) fixed to the upper end of the column (25) and fixedly connected to the outer ring surface of the syringe (11), and a collar (29) fixed to the rear side surface of the outer ring of the push rod (16), a connecting block (23) fixedly connected to the right side wall of the clamp (26) on the front side, and a connecting rod (28) fixedly connected to the right side wall of the collar (29); The front end face of the connecting rod (28) is fixedly connected to a rack (27) that passes through the connecting block (23); a servo motor (24) is installed on the rear side wall of the connecting block (23); and the output shaft of the servo motor (24) is connected to a gear (22) that meshes with the left tooth surface of the rack (27) through a coupling.

2. The interventional infusion device for blocking the blood supply of tumor tissue according to claim 1, characterized in that: The rear section of the outer ring surface of the syringe (11) is provided with a thread, and the rear end port of the syringe (11) is provided with a syringe end cover (15) by screwing the thread.

3. The interventional infusion device for blocking the blood supply of tumor tissue according to claim 1, characterized in that: The inner cavity of the syringe (11) is filled with medicine required for interventional infusion, and the end of the infusion catheter (13) away from the needle mouth (12) is inserted into the femoral artery of the human body.

4. The interventional infusion device for blocking the blood supply of tumor tissue according to claim 1, characterized in that: The outer ring surface of the piston (14) is in close contact with the inner cavity side wall of the syringe (11), and a through hole for the push rod (16) to penetrate and move is opened at the inner center position of the syringe end cover (15).

5. The interventional infusion device for blocking the blood supply of tumor tissue according to claim 1, characterized in that: The axis of the connecting block (23) and the axis of the connecting rod (28) are coaxially arranged.

6. The interventional infusion device for blocking the blood supply of tumor tissue according to claim 1, characterized in that: The connection block (23) is provided with a circular hole inside for the rack (27) to pass through.

7. The interventional infusion device for blocking the blood supply of tumor tissue according to claim 1, characterized in that: A protrusion is fixedly connected to the rear end surface of the connection block (23), and the side wall of the housing of the servo motor (24) is fixedly connected to the rear end of the protrusion.

8. The interventional infusion device for blocking the blood supply to tumor tissue according to claim 1, characterized in that: The bottom end surface of the column (25) is fixedly connected to a rectangular frame (21), and the bottom end surface of the rectangular frame (21) is fixedly connected to a layer of rubber pad via an adhesive.

9. The interventional infusion device for blocking the blood supply of tumor tissue according to claim 1, characterized in that: The meshing between the servo motor (24) and the gear (22) adopts a gear set design with an adjustable speed ratio so as to adjust the injection speed according to the viscosity of the medicine.

10. The interventional infusion device for blocking the blood supply of tumor tissue according to claim 1, characterized in that: The inner wall of the infusion catheter (13) is coated with an anti-adhesion coating to reduce the amount of drug residue on the inner wall of the catheter, thereby improving the drug delivery efficiency. A detachable connection structure is provided between the column (25) and the rectangular frame (21) to facilitate convenient maintenance and cleaning of the equipment.

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