Pediatric spleen and stomach plaster traditional Chinese medicine composition and preparation method thereof

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and discloses a pediatric spleen and stomach plaster traditional Chinese medicine composition and a preparation method thereof, and the key point of the technical scheme is that the traditional Chinese medicine composition is prepared from the following raw medicinal materials in parts by weight: lindera aggregata, agastache rugosus, pericarpium citri reticulatae viride, raw atractylodes macrocephala koidz and rhizoma corydalis. According to the spleen and stomach plaster provided by the invention, the medicine with the warm tonifying property is applied to the corresponding acupuncture point, and the whole function of the internal organs of the human body is adjusted through the stimulation effect of the medicine, the skin permeation effect and the channel tropism property of the acupuncture point, so that the treatment purpose is achieved. The traditional Chinese medicine composition has good treatment effects on anorexia, stomachache, constipation, vomiting and other symptoms caused by deficiency-cold in spleen and stomach, and is suitable for children of all ages.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, and more specifically to a pediatric spleen and stomach plaster traditional Chinese medicine composition and a preparation method thereof. Background Art

[0002] Spleen and stomach deficiency and coldness refer to the symptoms of spleen and stomach yang deficiency and internal yin and coldness. It includes spleen yang deficiency and stomach yang deficiency (some people think it refers to spleen yang deficiency alone), which are mostly caused by eating disorders, eating too much raw and cold food, overwork, or long-term illness or worry that hurts the spleen. Spleen yang deficiency syndrome can be seen with poor appetite, abdominal distension, abdominal pain but preference for warmth and pressure, bland mouth without thirst, cold limbs, loose stools, or edema of the limbs, fear of cold and preference for warmth, clear and long urination or unfavorable urination, clear and thin leucorrhea in women, pale, plump and tender tongue, white and moist tongue coating, and slow pulse. Stomach yang deficiency often causes pain due to cold weather, cold food and cold products. The pain is accompanied by a cold feeling in the stomach, and the symptoms are relieved by warmth. The stomachache is dull and continuous, with discomfort caused by cold, prefers warmth and pressure, is more severe on an empty stomach, relieved by food, and attacks or worsens after fatigue, cold food, or cold exposure, vomiting of clear water, less food, fatigue, cold hands and feet, loose stools, pale tongue with white fur, and weak pulse. The key points of differentiation for stomach yang deficiency syndrome are the symptoms of stomach disharmony and descent and the manifestations of yang deficiency syndrome, while the key points of differentiation for spleen yang deficiency syndrome are the symptoms of spleen deficiency and dysfunction and the manifestations of deficiency-cold syndrome.

[0003] Spleen and stomach deficiency and coldness can easily cause anorexia, abdominal pain, constipation, vomiting and other symptoms. The above symptoms not only affect the child's absorption of nutrients and growth and development, but can also lead to shock and death in severe cases. There are many drug preparations on the market for treating children's spleen and stomach deficiency and coldness, including Western medicine and Chinese medicine. Western medicine has great side effects, and Chinese medicine has a more unpleasant smell. Since taking medicine has certain side effects, feeding children medicine is also a problem.

[0004] Therefore, the present invention provides a pediatric spleen and stomach plaster Chinese medicine composition and a preparation method thereof. Summary of the invention

[0005] The purpose of the present invention is to provide a Chinese medicine composition for pediatric spleen and stomach plaster.

[0006] In order to achieve the above object, the technical solution adopted by the present invention is:

[0007] A Chinese medicine composition for pediatric spleen and stomach plaster, which is composed of the following raw medicinal materials in parts by weight: 80-120g of Linderae umbellatae, 80-120g of Patchouli, 80-120g of Citrus aurantium, 80-120g of Atractylodes macrocephala, and 80-120g of Corydalis yanhusuo.

[0008] Preferably, the Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 90-110g of Linderae strychnifolia, 90-110g of Patchouli, 90-110g of Citrus aurantium, 90-110g of Atractylodes macrocephala, 90-110g of Corydalis yanhusuo

[0009] Preferably, the traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 100g of Linderae umbellatae, 100g of Patchouli scabrae, 100g of Citrus aurantium, 100g of Atractylodes macrocephala, and 100g of Corydalis yanhusuo.

[0010] Another object of the present invention is to provide a method for preparing the above-mentioned Chinese medicine composition.

[0011] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0012] S1: Grind the prescribed amount of Linderae rutaecarpa, Patchouli Root, Citrus Atractylodes Macrocephala, and Rhizoma Corydalis into powder to obtain medicinal powder;

[0013] S2: adding the medicinal powder to a suitable matrix, stirring evenly to a paste, and obtaining a paste of a traditional Chinese medicine composition;

[0014] S3: The paste of the Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0015] Preferably, in step S1, the medicinal powder is an extremely fine powder.

[0016] Ultrafine powder refers to powder that can completely pass through the No. 8 sieve and contains no less than 95% of the powder that can pass through the No. 9 sieve; the mesh number of the No. 8 sieve is 150 mesh, and the mesh number of the No. 9 sieve is 200 mesh.

[0017] Preferably, in step S2, the matrix is ​​any one or more of rubber, thermoplastic rubber, rosin, rosin derivatives, vaseline, lanolin and zinc oxide.

[0018] Preferably, the matrix is ​​vaseline.

[0019] Preferably, the mass ratio of the drug powder to the matrix is ​​1:1.

[0020] Another object of the present invention is to provide the use of the above-mentioned pediatric spleen and stomach plaster Chinese medicine composition in the preparation of a medicine for treating anorexia, abdominal pain, constipation or vomiting caused by spleen and stomach deficiency and cold.

[0021] It should be noted that the pharmacological effects of some of the raw materials in the formula of the present invention are as follows:

[0022] Lindera agregata: It is the dried root of the plant Lindera agregata (Sims) Kos-term. of the Lauraceae family. Nature and flavor and meridians: pungent, warm. It enters the lung, spleen, kidney, and bladder meridians. Functions and indications: It promotes qi and relieves pain, warms the kidney and dispels cold. It is used for cold stagnation and qi stagnation, chest and abdominal distension and pain, qi reversal and shortness of breath, bladder deficiency and coldness, enuresis and frequent urination, hernia pain, and abdominal pain caused by cold menstruation.

[0023] Patchouli: The whole herb or aerial part of Agastache rugosa (Fisch. et Mey.) Q. Ktze., a plant of the Lamiaceae family. Nature and flavor and meridians: slightly warm in nature, pungent in taste. It enters the lung meridian, spleen meridian, and stomach meridian. Functions and indications: aromatic to eliminate dampness, soothe the stomach and stop vomiting, dispel heat and relieve the symptoms. It is used to treat dampness blocking the middle jiao, abdominal distension, loss of appetite, vomiting, diarrhea, headache caused by cold and heat due to exogenous summer dampness, fever and fatigue at the beginning of damp-heat, chest discomfort and nausea, sinusitis, and tinea manuum and pedis.

[0024] Green peel: It is the dried young or immature fruit peel of Citrus reticulata Blanco and its cultivars. Nature and flavor and meridians: bitter, pungent, warm. It enters the liver, gallbladder, and stomach meridians. Functions and indications: It can relieve cold, dispel wind and relieve pain, clear the nasal passages, dry dampness and stop leukorrhea, reduce swelling and discharge pus. It can soothe the liver and resolve qi, eliminate stagnation and resolve stagnation. It is used for chest and flank distension and pain, hernia pain, breast lumps, breast abscesses, food accumulation and qi stagnation, and abdominal distension and pain.

[0025] Raw Atractylodes: It is the dried rhizome of Atractylodes macrocephala Koidz. of the Asteraceae family. Nature and flavor and meridians: bitter, sweet, warm. It enters the spleen and stomach meridians. Functions and indications: Strengthen the spleen and replenish qi, dry dampness and promote diuresis, stop sweating, and stabilize the fetus. It is used for spleen deficiency, poor appetite, abdominal distension and diarrhea, phlegm and fluid, dizziness and palpitations, edema, spontaneous sweating, and restless fetuses.

[0026] Yuanhu: It is the dried tuber of Corydalisyanhusuo WTWW, a plant of the Poppy family. Nature and flavor and meridians: pungent, bitter, warm. It enters the liver and spleen meridians. Functions and indications: activating blood circulation, promoting qi, and relieving pain. It is used for chest and flank pain, abdominal pain, chest obstruction and heart pain, amenorrhea and dysmenorrhea, postpartum blood stasis, and swelling and pain due to falls.

[0027] It should also be noted that the method of using the spleen and stomach plaster prepared by the present invention is: 1 patch per day, applied to the patient's Zhongwan, Shenque or Tianshu acupoints, 5 days a course of treatment. Among them, Zhongwan warms the stomach and dispels cold, Shenque warms the spleen and relieves pain, and the bilateral Tianshu regulates the spleen and stomach, so that the spleen ascends and the stomach descends normally, the spleen and stomach function well, and diseases do not occur.

[0028] The present invention has the following beneficial effects:

[0029] 1. In the Chinese medicine composition of the present invention, Linderae odoratum warms the spleen and kidneys, Patchouli aromatically removes turbidity, Citrus aurantium promotes qi and eliminates stagnation, and Corydalis yanhusuo regulates qi and relieves pain while also entering the blood. All the medicines are used together to warm the spleen and stomach and regulate qi and relieve pain.

[0030] 2. The spleen and stomach plaster of the present invention applies the medicine with warming and nourishing properties to the corresponding acupuncture points, and regulates the overall function of the human internal organs to achieve the purpose of treatment through the stimulation of the medicine itself, the skin penetration effect, and the meridian properties of the acupuncture points. It has a good therapeutic effect on anorexia, abdominal pain, constipation, vomiting and other symptoms caused by spleen and stomach deficiency and cold, and is suitable for children of all ages. DETAILED DESCRIPTION

[0031] In order to enable those skilled in the art to better understand the solution of the present invention, the technical solution of the present invention will be further described in detail below in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in the field without creative work should fall within the scope of protection of the present invention.

[0032] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present invention can be combined with each other. The present invention will be described in detail below in conjunction with the embodiments.

[0033] Embodiment 1:

[0034] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0035] S1: Grind 100g of Linderae rutaecarpa, 100g of Patchouli, 100g of Citrus aurantium, 100g of Atractylodes macrocephala, and 100g of Corydalis into very fine powder to obtain medicinal powder;

[0036] S2: adding the drug powder to an equal amount of vaseline, stirring evenly to a paste state, to obtain a paste of the Chinese medicine composition;

[0037] S3: The paste of the Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0038] Embodiment 2:

[0039] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0040] S1: Grind 80g of Linderae rutaecarpa, 80g of Patchouli, 80g of Citrus aurantium, 120g of Atractylodes macrocephala, and 120g of Corydalis into very fine powder to obtain medicinal powder;

[0041] S2: adding the medicinal powder to an equal amount of lanolin, stirring evenly to a paste, and obtaining a paste of the Chinese medicine composition;

[0042] S3: The paste of the Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0043] Embodiment three:

[0044] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0045] S1: Grind 120g of Linderae rutaecarpa, 120g of Patchouli, 80g of Citrus aurantium, 80g of Atractylodes macrocephala, and 80g of Rhizoma Corydalis into very fine powder to obtain medicinal powder;

[0046] S2: adding the medicinal powder to an equal mass of the rosin derivative, stirring evenly to a paste, to obtain a paste of the Chinese medicine composition;

[0047] S3: The paste of the Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0048] Embodiment 4:

[0049] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0050] S1: Grind 110g of Linderae rutaecarpa, 90g of Patchouli, 110g of Citrus aurantium, 90g of Atractylodes macrocephala, and 90g of Corydalis into very fine powder to obtain medicinal powder;

[0051] S2: adding the drug powder to an equal mass of thermoplastic rubber, stirring evenly to a paste state, and obtaining a paste of the Chinese medicine composition;

[0052] S3: The paste of the Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0053] Embodiment five:

[0054] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0055] S1: Grind 90g of Linderae rutaecarpa, 90g of Patchouli, 90g of Citrus aurantium, 110g of Atractylodes macrocephala, and 110g of Corydalis into very fine powder to obtain medicinal powder;

[0056] S2: adding the drug powder to an equal amount of vaseline, stirring evenly to a paste state, to obtain a paste of the Chinese medicine composition;

[0057] S3: The paste of the Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0058] Clinical trial cases:

[0059] To prove that the spleen and stomach plaster prepared by the Chinese medicine composition of the present invention has the positive effects of dispersing exogenous pathogens and promoting the descending of lung qi, the inventors conducted a large number of clinical trials on the spleen and stomach plaster prepared in Example 1, and now select some clinical trials to report as follows.

[0060] Case 1: Li Musheng, male, 2 years and 9 months old, had abdominal pain for 1 month, mainly in the left lower abdomen, dry stool, and defecation once every 2-3 days. He was given a spleen and stomach plaster to apply to Shenque and Tianshu points, and after 1 course of treatment, all symptoms were relieved.

[0061] Case 2: Xu Qiantong, female, 2 years and 9 months old, had intermittent abdominal pain for 1 week, mainly around the umbilicus. Abdominal ultrasound showed enlarged mesenteric lymph nodes, but no other obvious abnormalities were found. Intermittent oral belladonna tablets and Lactobacillus acidophilus tablets were not effective. After a course of applying spleen and stomach plaster on Shenque and Tianshu points, the abdominal pain was relieved.

[0062] Case 3: Qu Sirui, female, 10 years and 11 months old, had vomiting symptoms 2 days ago due to careless diet. The vomitus was undigested gastric contents, 2-3 times / day, not in a jet-like state. She was given a spleen and stomach plaster to apply to Zhongwan, Shenque, and Tianshu, 2-4 hours / time, once / day, for a total of 2 days, and the symptoms were relieved.

[0063] Case 4: Cui Zeren, male, 4 years and 7 months old, had loose stools and increased frequency for more than a month. The child had loose stools for more than a month, 3-4 times / day, without mucus, pus or blood. He was treated with oral probiotics and montmorillonite powder, but the effect was not good. He was given 2 courses of spleen and stomach plaster on Shenque and Tianshu points, and the symptoms were relieved.

[0064] Case 5: Sha Ziheng, male, 5 years and 9 months old, the child usually has dry stool and irregular bowel movements, with bowel movements once every 3-5 days. Intermittent oral probiotic treatment had poor efficacy, and he was given a spleen and stomach plaster applied to the Tianshu acupoint. After 2 courses of treatment, the stool became soft and he had bowel movements once every 1-2 days.

[0065] Case 6: Yu Yucheng, male, 3 years and 4 months old, had abdominal pain for more than half a year, mainly in the upper abdomen, accompanied by nausea and vomiting. Electronic gastroscopy showed gastritis. He took medication regularly, but still had intermittent abdominal pain. He applied spleen and stomach plaster on Zhongwan, Tianshu and Guanyuan acupoints. After 4 courses of treatment, the pain was relieved.

[0066] Case 7: Liu Ruoxi, female, 3 years and 2 months old, had intermittent abdominal pain for more than a month, mainly around the umbilicus, without nausea and vomiting. She was given a course of Piwei Plaster on Shenque and Tianshu acupoints, and the pain was relieved.

[0067] Case 8: Zhao Linyu, female, 4 years old, had poor appetite for 1 year, no abdominal pain, bloating, nausea and vomiting, and normal bowel movements. She was given a spleen and stomach plaster on the Zhongwan, Shenque, and Tianshu points for 2 courses of treatment, and her appetite improved.

[0068] Case 9: Guo Siyu, male, 12 years and 5 months old, had diarrhea 2 weeks ago and was treated with oral montmorillonite powder, probiotics and other drugs. He then developed dry stools and defecated once every 3-4 days. He was given a course of spleen and stomach plaster and his constipation symptoms improved.

[0069] Case 10: Liu Yuqi, female, 6 years and 6 months old, had intermittent abdominal pain for more than half a month, with no fixed tenderness in the whole abdomen. Abdominal ultrasound showed no obvious abnormalities. She was given 2 courses of spleen and stomach plaster and her symptoms were relieved.

[0070] In summary, the spleen and stomach plaster prepared by the present invention has the functions of warming the spleen and stomach, regulating qi and relieving pain, and has the efficacy and the like, and is mainly used to treat anorexia, abdominal pain, diarrhea, constipation, vomiting and the like.

[0071] This specific embodiment is merely an explanation of the present invention and is not a limitation of the present invention. After reading this specification, those skilled in the art may make non-creative modifications to the present embodiment as needed. However, as long as they are within the scope of the claims of the present invention, they are protected by the patent law.

Claims

1. A Chinese medicine composition for pediatric spleen and stomach plaster, characterized in that: The traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 80-120g of Linderae umbellatae, 80-120g of Patchouli, 80-120g of Citrus aurantium, 80-120g of Atractylodes macrocephalae, and 80-120g of Corydalis yanhusuo.

2. A pediatric spleen and stomach plaster Chinese medicine composition according to claim 1, characterized in that, The traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 90-110g of Linderae umbellatae, 90-110g of Patchouli, 90-110g of Citrus aurantium, 90-110g of Atractylodes macrocephalae, and 90-110g of Corydalis yanhusuo.

3. A pediatric spleen and stomach plaster Chinese medicine composition according to claim 2, characterized in that, The traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 100g of Linderae umbellatae, 100g of Patchouli scabrae, 100g of Citrus aurantium, 100g of Atractylodes macrocephalae, and 100g of Corydalis yanhusuo.

4. A method for preparing the Chinese medicine composition of the pediatric spleen and stomach plaster according to any one of claims 1 to 3, characterized in that: The steps include: S1: Grind the prescribed amount of Linderae rutaecarpa, Patchouli Root, Citrus Atractylodes Macrocephala, and Rhizoma Corydalis into powder to obtain medicinal powder; S2: adding the medicinal powder to a suitable matrix, stirring evenly to a paste, and obtaining a paste of a traditional Chinese medicine composition; S3: The paste of the Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen-strengthening paste.

5. The method for preparing the pediatric spleen and stomach plaster Chinese medicine composition according to claim 4, characterized in that: In step S1, the medicinal powder is an extremely fine powder.

6. The method for preparing the pediatric spleen and stomach plaster Chinese medicine composition according to claim 4, characterized in that: In step S2, the matrix is ​​any one or more of rubber, thermoplastic rubber, rosin, rosin derivatives, vaseline, lanolin and zinc oxide.

7. The method for preparing the pediatric spleen and stomach plaster Chinese medicine composition according to claim 4, characterized in that: The matrix is ​​vaseline.

8. The method for preparing the Chinese medicine composition of the pediatric spleen and stomach plaster according to claim 4, 6 or 7, characterized in that: The mass ratio of the drug powder to the matrix is ​​1:

1.

9. Use of the Chinese medicine composition of the pediatric spleen and stomach plaster according to any one of claims 1 to 3 in the preparation of a medicine for treating anorexia, abdominal pain, constipation or vomiting caused by spleen and stomach deficiency and cold.