Pharmaceutical composition for treating liver cancer

Abstract

The invention relates to the technical field of biological medicines, and provides a pharmaceutical composition for treating liver cancer, which is prepared from the following raw material medicines in parts by weight: 3 to 8 parts of radix paeoniae rubra, 1 to 3 parts of fructus sophorae, 3 to 10 parts of rhizoma polygoni cuspidati, 3 to 20 parts of spica prunellae, 3 to 20 parts of herba hedyotidis diffusae, 3 to 10 parts of herba violae, 2 to 5 parts of turtle shell, 1 to 5 parts of radix angelicae sinensis, 1 to 3 parts of rhizoma curcumae, 1 to 3 parts of apios fortunei maxim and 3 to 5 parts of fructus polygoni orientalis. According to the technical scheme, the problems that in the prior art, after radiotherapy and chemotherapy are conducted on patients, obvious side effects can be generated, such as the symptoms of inappetence, nausea and vomiting, diarrhea, stomachache, dental ulcer and the like, and some patients have the symptoms of listlessness, weakness, shortness of breath, alopecia and the like are solved.

Description

Technical Field

[0001] The present invention relates to the field of biomedicine technology, and in particular to a pharmaceutical composition for treating liver cancer. Background Art

[0002] Liver cancer is a malignant tumor of the liver, which can be divided into two categories: primary and secondary. Primary malignant liver tumors originate from the epithelial or mesenchymal tissue of the liver. The former is called primary liver cancer, which is a common and extremely harmful malignant tumor; the latter is called sarcoma, which is relatively rare compared with primary liver cancer. Secondary or metastatic liver cancer refers to malignant tumors originating from multiple organs throughout the body that invade the liver.

[0003] At present, individualized comprehensive treatment according to the different stages of liver cancer is the key to improving the efficacy; treatment methods include surgery, hepatic artery ligation, hepatic artery chemoembolization, radiofrequency, cryosurgery, laser, microwave, chemotherapy, targeted therapy, immunotherapy and radiotherapy. Currently, there are six types of liver cancer treatment methods:

[0004] 1. Surgical treatment: Surgery is the first choice and the most effective method for treating liver cancer. Surgical methods include radical liver resection, palliative liver resection, etc. For liver cancer that cannot be removed, according to the specific situation, intraoperative hepatic artery ligation, hepatic artery chemoembolization, radiofrequency, freezing, laser, microwave and other treatments can have certain effects. Primary liver cancer is also one of the indications for liver transplantation.

[0005] 2. Chemotherapy: If the laparotomy reveals that the tumor cannot be removed, or as a follow-up treatment for palliative tumor resection, regional chemoembolization can be performed by placing a pump (subcutaneous buried perfusion device) in the hepatic artery and / or portal vein. For those who are estimated to be unresectable by surgery, radiological intervention can also be performed. Selective catheterization is performed through the femoral artery to the hepatic artery, and embolic agents (commonly used such as iodized oil) and anticancer drugs are injected for chemoembolization. Some patients can therefore have the opportunity for surgical resection.

[0006] 3. Radiotherapy: For patients with good general condition, good liver function, no cirrhosis, no jaundice, ascites, hypersplenism and esophageal varices, relatively localized cancer, no distant metastasis, but not suitable for surgical resection or recurrence after surgery, comprehensive treatment with radiation as the main method can be used.

[0007] 4. Biological therapy: Commonly used ones include immune RNA, interferon, interleukin-2, thymosin, etc., which can be used in combination with chemotherapy.

[0008] 5. Targeted drug therapy: Liver cancer can be treated with targeted drugs, such as oral sorafenib, which has relatively few side effects and a relatively high treatment efficiency. It is suitable for patients with mid- to late-stage liver cancer. The second generation of targeted drugs has begun to be used in clinical practice. Patients can obtain targeted drugs based on their own conditions for targeted treatment.

[0009] 6. Immunotherapy: Immunotherapy for liver cancer includes immunosuppressants, immunomodulators, tumor vaccines, and cellular immunotherapy. Immunotherapy interferes with and inhibits immune function, regulates the body and enhances the body's immunity, inhibits and kills liver cancer cells, and thus controls the progression of liver cancer. Commonly used drugs include interferon, freeze-dried BCG, transfer factor, tumor necrosis factor, interleukin, thymosin, etc. Treatment can improve the patient's immunity and prevent further development of liver cancer.

[0010] Radiotherapy, chemotherapy and targeting are all common anticancer methods clinically, mainly using anticancer drugs or radiation for treatment, which can inhibit cancer cell proliferation and metastasis, and avoid symptom aggravation, but this method has a greater impact on the body. Patients will have more obvious side effects after carrying out radiotherapy and chemotherapy and using targeting and immune drugs, such as loss of appetite, nausea and vomiting symptoms, and various problems such as diarrhea, abdominal pain, oral ulcers will also occur at the same time, and some patients will have symptoms such as mental depression, fatigue, shortness of breath, and hair loss. Traditional Chinese medicine treatment of liver cancer is also widely used. At present, more and more Chinese medicine prescriptions are used in the adjuvant treatment of liver cancer, in order to improve the quality of life and survival period of patients by adjusting the body's immune function, reducing chemotherapy side effects, inhibiting tumor growth and other modes, the present invention adopts the mode of traditional Chinese medicine treatment, adopts the method of syndrome differentiation and treatment, and the method of attacking and supplementing, often in conjunction with other therapies, to improve the body's disease resistance, improve general condition and symptoms, and reduce chemotherapy and radiotherapy adverse reactions. Summary of the invention

[0011] The present invention proposes a drug composition for treating liver cancer, which solves the problem in related technologies that patients will experience relatively obvious side effects after undergoing radiotherapy, chemotherapy, targeted and immune drug treatments, such as loss of appetite, nausea and vomiting, as well as diarrhea, abdominal pain, oral ulcers and other problems. Some patients will experience symptoms such as mental depression, fatigue, shortness of breath, and hair loss.

[0012] The technical solution of the present invention is as follows:

[0013] A pharmaceutical composition for treating liver cancer, the pharmaceutical composition comprising the following raw materials in parts by weight:

[0014] 3-8 parts of red peony root, 1-3 parts of Sophora japonica, 3-10 parts of Polygonum cuspidatum, 3-10 parts of Artemisia capillaris, 3-10 parts of Taraxacum officinale, 3-10 parts of Viola yedoensis, 1-3 parts of Licorice, 1-5 parts of Angelica sinensis, 2-10 parts of Millettia yunnanensis, 3-10 parts of Panax notoginseng, 5-10 parts of Patrinia salsa, 1-5 parts of Aconite, 5-20 parts of Coix seeds, 3-20 parts of Prunella vulgaris, 3-20 parts of Hedyotis diffusa, 3-10 parts of Scutellaria barbata, 2-10 parts of Ipomoea batatas, 2-5 parts of Cypress on stone, 3-10 parts of Pinellia ternata, 2-4 parts of Morus alba, 2-10 parts of Lepidium officinale, 3-10 parts of Solanum nigrum, Crane 3-10 parts of grass, 3-10 parts of creeping pot grass, 2-5 parts of lobelia, 2-10 parts of mulberry, 3-9 parts of astilbe, 2-10 parts of root vegetable, 2-5 parts of hawthorn, 2-6 parts of chicken's gizzard lining, 3-10 parts of roasted malt, 0.1-0.3 parts of bear bile powder, 0.2-0.4 parts of bezoar, 2-5 parts of turtle shell, 2-5 parts of tortoise shell, 0.5-1 parts of centipede, 1-2 parts of dragon, 1-3 parts of scorpion, 1-6 parts of mountain ridge, 1-3 parts of curcuma, 2-5 parts of pollen, 2-10 parts of tiankui seeds, 2-10 parts of tribulus ternata, 1-3 parts of earthworm, and 3-5 parts of water safflower seeds.

[0015] Further, the pharmaceutical composition is composed of the following raw materials in parts by weight: 4 parts of red peony root, 2 parts of sophora japonica, 6 parts of knotweed, 10 parts of wormwood, 8 parts of dandelion, 5 parts of viola yedoensis, 1 part of licorice, 4 parts of angelica, 8 parts of millettia spatholobi, 7 parts of panax quinquefolia, 6 parts of patrinia herb, 3 parts of aconite, 15 parts of coix seeds, 18 parts of selfheal, 6 parts of oldenlandia diffusa, 4 parts of barbata, 6 parts of calamus, 2 parts of cyperus rotundus, 10 parts of cyperus rotundus, 2 parts of mulberry bark, 10 parts of scutellaria baicalensis, 2 parts of scutellaria baicalensis, 4 parts of Semen Ligusticum chuanxiong, 10 parts of Solanum nigrum, 8 parts of Herba Agrimoniae, 5 parts of Herba Lycopodii, 2 parts of Herba Lobeliae, 4 parts of Cuscuta australis, 9 parts of Astilbe chinensis, 10 parts of Herba Lycopodii, 2 parts of Fructus Crataegi, 6 parts of Gallus gallbladder, 4 parts of Rhizoma Fructus Rhizoma, 0.1 parts of Bear Gall Powder, 0.4 parts of Calculus Bovis, 2 parts of Carapax Trichosanthis, 4 parts of Carapax Tortoise Shell, 0.5 parts of Scolopendra Subspinipes, 1 part of Dracaena, 1 part of Scorpio, 2 parts of Rhizoma Curcumae, 1 part of Pollen Typhae, 10 parts of Fructus Schizonepetae, 6 parts of Pleurotus eryngii, 1 part of Rhizoma Cynomorii, 3 parts of Fructus Polygoni Multiflori.

[0016] Further, the pharmaceutical composition is composed of the following raw materials in parts by weight: 8 parts of red peony root, 3 parts of sophora japonica, 3 parts of knotweed, 3 parts of capillaris, 8 parts of dandelion, 3 parts of viola yedoensis, 3 parts of licorice, 5 parts of angelica, 10 parts of millet spatholobi, 10 parts of cat ginseng, 5 parts of patrinia, 2 parts of aconite, 5 parts of coix seeds, 15 parts of selfheal, 10 parts of oldenlandia diffusa, 5 parts of barbata, 2 parts of calathea, 5 parts of cyperus, 3 parts of cyperus, 4 parts of mulberry bark, 10 parts of scutellaria baicalensis ... 8 parts of seeds of Leonurus japonicus, 8 parts of nightshade, 3 parts of herba agrimonii, 8 parts of scutellariae, 2 parts of lobelia, 10 parts of mulberry trees, 7 parts of astilbe, 6 parts of radix scutellariae, 5 parts of hawthorn, 2 parts of chicken's gizzard lining, 10 parts of roasted malt, 0.2 part of bear's gall powder, 0.3 part of bezoar, 5 parts of turtle shell, 2 parts of tortoise shell, 0.8 part of centipede, 2 parts of scutellariae, 1 part of scorpion, 1 part of mountain ridge, 2 parts of zedoaria, 4 parts of pollen, 6 parts of seed of scutellariae, 10 parts of scutellariae, 2 parts of scutellariae, 4 parts of polyanthus polyphyllae.

[0017] Further, the pharmaceutical composition is composed of the following raw materials in parts by weight: 3 parts of red peony root, 1 part of sophora japonica, 10 parts of knotweed, 10 parts of wormwood, 10 parts of dandelion, 10 parts of viola yedoensis, 1 part of licorice, 1 part of angelica, 2 parts of millet spatholobi, 3 parts of cat ginseng, 10 parts of patrinia herb, 4 parts of aconite, 20 parts of coix seeds, 5 parts of selfheal, 3 parts of oldenlandia diffusa, 10 parts of barbata, 10 parts of calamus, 2 parts of cypress, 5 parts of plantain, 3 parts of mulberry bark 4 parts, 10 parts of Herba Lycopodii, 10 parts of Herba Agrimoniae, 10 parts of Herba Lycopodii, 2 parts of Herba Lobeliae, 2 parts of Herba Cudraniae, 3 parts of Astilbe, 2 parts of Herba Lycopodii, 4 parts of Fructus Crataegi, 4 parts of Gallus gallbladder, 6 parts of Rhizoma Fructus, 0.3 parts of Bear Gall Powder, 0.2 parts of Calculus Bovis, 3 parts of Carapax Trichosanthis, 2 parts of Carapax Turtle, 1 part of Scolopendra, 1 part of Dracaena, 3 parts of Scorpio, 6 parts of Ridge Mountain, 3 parts of Curcuma, 5 parts of Pollen Typhae, 2 parts of Fructus Schizonepetae, 2 parts of Psoralea corylifolia, 3 parts of Rhizoma Cynomorii, and 4 parts of Fructus Polygoni Multiflori.

[0018] Furthermore, the pharmaceutical composition is prepared as a decoction, a mixture, a capsule, a tablet, a powder, a pill, a granule, an atomizer, a spray, a fermentation agent, a patch, or an ointment.

[0019] Furthermore, the pharmaceutical composition is made into powder by crushing the pharmaceutical composition into powder by a pulverizer, and when it is made into capsules, the powder is filled into capsules.

[0020] Furthermore, the pharmaceutical composition is made into granules, and the pharmaceutical composition is formed into pharmaceutical granules through extraction, separation, concentration, drying and granulation processes, and the pharmaceutical granules can be drunk after being brewed with hot water.

[0021] Furthermore, when the pharmaceutical composition is made into tablets, the powder is used as a base, starch and medicinal dextrin are added, and the tablets are made after solidification and drying.

[0022] The working principle and beneficial effects of the present invention are:

[0023] 1. The present invention proposes a Chinese medicine composition for treating liver cancer, which improves the quality of life and survival of patients by regulating the body's immune function, reducing the side effects of chemotherapy, inhibiting tumor growth, etc., and obtains an effect that is more beneficial to liver cancer patients, especially for liver cancer patients after radiotherapy or surgery. It has an important effect on improving the body function, thereby solving the problem that patients will have more obvious side effects after radiotherapy and chemotherapy, such as loss of appetite, nausea and vomiting, diarrhea, abdominal pain, oral ulcers and other problems. Some patients will experience symptoms such as mental depression, fatigue, shortness of breath, and hair loss.

[0024] 2. Among them, Tu'er clears away heat and detoxifies, disperses blood stasis and relieves pain, nourishes yin and suppresses yang. It contains a variety of flavonoids and volatile oil components, has anti-tumor and antioxidant effects, and can inhibit the proliferation of tumor cells by regulating inflammatory factors; among them, Biejia softens and disperses nodules, clears away heat and removes steam, and is rich in collagen, a variety of trace elements and minerals. It inhibits tumor angiogenesis through its pharmacological properties of softening nodules; the pathogenesis of liver cancer is mostly liver qi stagnation, damp heat and evil toxins. Through the two functional medicinal materials, Tu'er can directly kill tumor cells, and Biejia can improve the tumor microenvironment, thereby assisting in the treatment of liver cancer symptoms.

[0025] 3. The combination of Tu'er and Biejia can exert a synergistic effect under the influence of traditional Chinese medicine theory and modern pharmacology, and achieve a therapeutic effect far exceeding that of using either alone. Among them, Tu'er tends to attack evil and clear away heat, targeting heat toxicity and blood stasis syndrome; Biejia tends to strengthen the body and replenish deficiency, targeting yin deficiency with blood stasis and both deficiency and excess. By combining these two herbs, it is possible to give equal weight to clearing heat and detoxifying and nourishing yin and suppressing yang, reduce damage to vital energy, and avoid the limitations of over-attack or over-replenishment with a single drug. DETAILED DESCRIPTION

[0026] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0027] The present invention provides a pharmaceutical composition for treating liver cancer, wherein the pharmaceutical composition is composed of the following raw materials in parts by weight:

[0028] 3-8 parts of red peony root, 1-3 parts of Sophora japonica, 3-10 parts of Polygonum cuspidatum, 3-10 parts of Artemisia capillaris, 3-10 parts of Taraxacum officinale, 3-10 parts of Viola yedoensis, 1-3 parts of Licorice, 1-5 parts of Angelica sinensis, 2-10 parts of Millettia yunnanensis, 3-10 parts of Panax notoginseng, 5-10 parts of Patrinia salsa, 1-5 parts of Aconite, 5-20 parts of Coix seeds, 3-20 parts of Prunella vulgaris, 3-20 parts of Hedyotis diffusa, 3-10 parts of Scutellaria barbata, 2-10 parts of Ipomoea batatas, 2-5 parts of Cypress on stone, 3-10 parts of Pinellia ternata, 2-4 parts of Morus alba, 2-10 parts of Lepidium officinale, 3-10 parts of Solanum nigrum, Crane 3-10 parts of grass, 3-10 parts of creeping pot grass, 2-5 parts of lobelia, 2-10 parts of mulberry, 3-9 parts of astilbe, 2-10 parts of root vegetable, 2-5 parts of hawthorn, 2-6 parts of chicken's gizzard lining, 3-10 parts of roasted malt, 0.1-0.3 parts of bear bile powder, 0.2-0.4 parts of bezoar, 2-5 parts of turtle shell, 2-5 parts of tortoise shell, 0.5-1 parts of centipede, 1-2 parts of dragon, 1-3 parts of scorpion, 1-6 parts of mountain ridge, 1-3 parts of curcuma, 2-5 parts of pollen, 2-10 parts of tiankui seeds, 2-10 parts of tribulus ternata, 1-3 parts of earthworm, and 3-5 parts of water safflower seeds.

[0029] In this embodiment, the pharmaceutical composition is prepared as a decoction, a mixture, a capsule, a tablet, a powder, a pill, a granule, an atomizer, a spray, a fermentation agent, a patch, or an ointment.

[0030] In this embodiment, the pharmaceutical composition is prepared into powder by crushing the pharmaceutical composition into powder by a pulverizer, and when it is prepared into capsules, the powder is filled into the capsules.

[0031] In this embodiment, the pharmaceutical composition is made into granules. The pharmaceutical composition is subjected to extraction, separation, concentration, drying and granulation processes to form pharmaceutical granules. The pharmaceutical granules can be drunk after being brewed with hot water.

[0032] In this embodiment, when the pharmaceutical composition is made into tablets, starch and medicinal dextrin are added to the powder as the basis, and the tablets are made after solidification and drying.

[0033] The raw materials used in the pharmaceutical composition of the present invention are specifically described as follows:

[0034] Red Peony Root: bitter in taste, slightly cold in nature, enters the liver meridian. It has the effects of clearing heat, cooling blood, dispersing blood stasis and relieving pain.

[0035] Sophora japonica: bitter in taste, cold in nature. Enters the liver and large intestine meridians. Has the effects of clearing away heat and purging fire, cooling blood and stopping bleeding.

[0036] Polygonum cuspidatum: slightly bitter in taste, slightly cold in nature. Enters the liver, gallbladder, and lung meridians. It has the effects of promoting dampness and relieving jaundice, clearing away heat and detoxifying, dispersing blood stasis and relieving pain, and relieving cough and reducing phlegm.

[0037] Artemisia capillaris: bitter, pungent, slightly cold in nature. Enters the spleen, stomach, liver, and gallbladder meridians. Has the effects of clearing away dampness and heat, promoting bile secretion and relieving jaundice.

[0038] Dandelion: bitter, sweet, cold in nature. Enters the liver and stomach meridians. Has the effects of clearing away heat and detoxifying, reducing swelling and dispersing nodules, and promoting diuresis and relieving stranguria.

[0039] Viola yedoensis: bitter, pungent, cold in nature. Enters the heart and liver meridians. Has the effects of clearing away heat, detoxifying, cooling blood and reducing swelling.

[0040] Licorice: sweet in taste, neutral in nature. It enters the heart, lung, spleen, and stomach meridians. It has the main functions of tonifying the spleen and replenishing qi, clearing away heat and detoxifying, removing phlegm and relieving cough, relieving pain, and harmonizing.

[0041] Angelica: Sweet and spicy, warm in nature. Enters the liver, heart, and spleen meridians. Has the effects of nourishing blood, activating blood circulation, regulating menstruation and relieving pain, and moistening the intestines and relieving constipation.

[0042] Millettia yunnanensis: bitter, sweet, warm in nature. Enters the liver and kidney meridians. Has the effects of promoting blood circulation, replenishing blood, regulating menstruation and relieving pain, and relaxing muscles and tendons.

[0043] Cat ginseng: bitter, astringent, cool in nature. Enters the liver, spleen, stomach, and bladder meridians. Clears away heat, detoxifies, and reduces swelling.

[0044] Patrinia scabra: pungent, bitter, cool in nature. It has the effects of clearing away heat, detoxifying, removing phlegm and draining pus.

[0045] Aconite: Spicy and sweet, very hot in nature. Enters the heart, kidney and spleen meridians. It has the functions of restoring yang, replenishing fire and boosting yang, dispelling cold and relieving pain.

[0046] Coix seeds: sweet, light, slightly cold, non-toxic. Enter the spleen, stomach, lung, and large intestine meridians. It has the effects of clearing away heat and dampness, removing rheumatism, promoting urination, benefiting the lungs and draining pus, strengthening the spleen and stomach, and strengthening the tendons and bones.

[0047] Prunella Vulgaris: Spicy, bitter, cold in nature. Enters the liver and gallbladder meridians. Has the effects of clearing the liver and purging fire, improving eyesight, dispersing stagnation and reducing swelling.

[0048] Hedyotis diffusa: bitter, light, cold in nature. It has the effects of clearing away heat and detoxifying, relieving pain and dispersing stagnation, and promoting diuresis and removing dampness.

[0049] Lobelia: Spicy, neutral in nature. Enters the heart, small intestine, and lung meridians. Has the effects of clearing away heat and detoxifying, diuresis, and swelling.

[0050] Lithospermum officinale: bitter and pungent. Enters the liver and spleen meridians. Has the effects of promoting blood circulation and removing blood stasis, clearing away heat and dampness, and dispersing stagnation and reducing swelling.

[0051] Cypress: sweet, slightly bitter, astringent. Cool in nature. Enters the lung and liver meridians. Has the effects of clearing away heat and detoxification, anti-cancer, and hemostasis.

[0052] Pinellia ternata: Spicy and slightly bitter. Neutral. Enters the lung and liver meridians. Has the effects of resolving phlegm and relieving cough, promoting dampness and promoting blood circulation.

[0053] Morus alba bark: sweet in taste, cold in nature. It enters the lung and spleen meridians, has the effects of purging the lungs and relieving asthma, promoting water circulation and reducing swelling.

[0054] Tinglizi: Spicy and bitter. Cold in nature. Enters the lung, bladder, and large intestine meridians. Has the effects of purging the lungs and lowering qi, removing phlegm and relieving asthma, promoting diuresis and reducing swelling, and purging heat and expelling evil.

[0055] Solanum nigrum: bitter in taste, cold in nature. It has the effects of clearing away heat, detoxifying, promoting blood circulation and reducing swelling.

[0056] Agrimony: bitter, astringent, neutral in nature. Enters the heart and liver meridians. Has the effects of astringing, stopping bleeding, stopping diarrhea, detoxifying, and replenishing deficiency.

[0057] Herba Lycopodii: sweet, light, cool in nature. Enters the liver, gallbladder, and small intestine meridians. Has the effects of removing dampness and jaundice, clearing away heat and detoxifying.

[0058] Scutellaria barbata: Spicy and bitter in taste, cold in nature. Enters the lung, liver and kidney meridians. Has the effects of clearing away heat and detoxifying, removing blood stasis and promoting diuresis.

[0059] Cudrania: Sweet in taste, warm in nature. Enters the liver and spleen meridians. Has the effect of nourishing blood vessels and regulating the spleen and stomach.

[0060] Astilbe: bitter, astringent, cool in nature, non-toxic. It has the effects of dispelling wind, clearing heat, relieving cough, relieving pain, and promoting blood circulation and removing blood stasis.

[0061] Chegencai: bitter, slightly spicy, warm in nature. Enters the liver and kidney meridians. Has the effects of diuresis, dehumidification, blood circulation, blood stasis, hemostasis, and detoxification.

[0062] Hawthorn: sour, sweet, slightly warm in nature. Enters the spleen, stomach, and liver meridians. Has the effects of helping digestion, strengthening the stomach, promoting qi and dispersing blood stasis, clearing turbidity and reducing fat.

[0063] Chicken gizzard lining: sweet in taste, neutral in nature. Enters the spleen, stomach, small intestine, and bladder meridians. Has the effects of strengthening the stomach and digestion, astringing sperm and stopping nocturnal emission, and clearing stranguria and dissolving stones.

[0064] Fried malt: sweet in taste, neutral in nature, enters the spleen and stomach meridians. It has the effects of promoting qi and digestion, strengthening the spleen and stimulating appetite.

[0065] Bear bile powder: extremely bitter, cold in nature, enters the liver meridian. It has the effects of clearing heat, calming the liver, and improving eyesight.

[0066] Bezoar: sweet in taste, cool in nature, enters the heart and liver meridians. It has the effects of clearing the heart, resolving phlegm, promoting gallbladder function, and calming the nerves.

[0067] Turtle shell: salty, slightly cold. Enters the liver and kidney meridians. Has the effects of nourishing yin and suppressing yang, reducing fever and removing steam, softening and dispersing nodules. Turtle shell: salty, sweet, slightly cold. Enters the liver, kidney, and heart meridians. Has the effects of nourishing yin and suppressing yang, strengthening the kidney and strengthening bones, nourishing blood and nourishing the heart, and consolidating menstruation and stopping metrorrhagia.

[0068] Tuan Er: Sweet, slightly bitter, neutral in nature. Enters the lung and spleen meridians. Has the effects of clearing away heat and detoxifying, dispersing blood stasis and relieving pain, softening and dispersing lumps.

[0069] Centipede: pungent, warm. Enters the liver meridian. Has the effects of calming wind and relieving spasm, dredging meridians and relieving pain, and attacking toxins and dispersing stagnation.

[0070] Tianlong: salty in taste, cold in nature. Enters the kidney and liver meridians. Has the effects of dispelling wind, activating collaterals, and dispersing nodules.

[0071] Scorpion: pungent, neutral. Enters the liver meridian. Has the effects of calming wind and relieving spasm, dredging meridians and relieving pain, and attacking toxins and dispersing stagnation.

[0072] Rhizoma Cistanches: pungent, bitter, neutral. Enters the liver and spleen meridians. Has the effects of breaking blood and promoting qi, eliminating accumulation and relieving pain.

[0073] Curcuma: pungent, bitter, warm. Enters the liver and spleen meridians. Has the functions of promoting qi and relieving depression, removing blood stasis and relieving pain.

[0074] Pollen Puhuang: sweet, neutral. Enters the liver and pericardium meridians. Has the effects of stopping bleeding, removing blood stasis and relieving stranguria.

[0075] Tiankuizi: sweet, bitter, cold in nature. Enters the liver and stomach meridians. Has the effects of clearing away heat, detoxifying, reducing swelling and dispersing nodules.

[0076] Trillium: sweet, slightly spicy, cool in nature. Enters the liver and spleen meridians. Has the effects of clearing away heat, detoxifying, resolving phlegm and dispersing stagnation.

[0077] Polygonum multiflorum seeds: salty, slightly cold. Enters the liver and stomach meridians. Has the effects of dispersing blood, eliminating lumps, relieving accumulation and relieving pain, and promoting diuresis and reducing swelling.

[0078] Example 1

[0079] A pharmaceutical composition for treating liver cancer, the pharmaceutical composition is composed of the following raw materials in parts by weight:

[0080] 4 parts of red peony root, 2 parts of sophora japonica, 6 parts of knotweed, 10 parts of wormwood, 8 parts of dandelion, 5 parts of viola yedoensis, 1 part of liquorice, 4 parts of angelica, 8 parts of millet blood vine, 7 parts of cat ginseng, 6 parts of patrinia, 3 parts of aconite, 15 parts of coix seeds, 18 parts of selfheal, 6 parts of oldenlandia diffusa, 4 parts of barbata, 6 parts of cyperus, 2 parts of cypress, 10 parts of flatwood, 2 parts of mulberry bark, 4 parts of scutellaria, 10 parts of nightshade, crane 8 parts of grasses, 5 parts of creeping pot grass, 2 parts of lobelia, 4 parts of mulberry trees, 9 parts of astilbe, 10 parts of radix scutellariae, 2 parts of hawthorns, 6 parts of chicken's gizzard lining, 4 parts of roasted malt, 0.1 part of bear gall powder, 0.4 part of bezoars, 2 parts of turtle shells, 4 parts of tortoise shells, 0.5 part of centipede, 1 part of dragon shells, 1 part of scorpion, 2 parts of mountain ridges, 1 part of curcuma, 2 parts of pollen, 10 parts of scutellariae, 6 parts of smilax china, 1 part of scutellariae, 3 parts of polyanthus polyphyllae.

[0081] Example 2

[0082] A pharmaceutical composition for treating liver cancer, the pharmaceutical composition is composed of the following raw materials in parts by weight:

[0083] 8 parts of red peony root, 3 parts of sophora japonica, 3 parts of knotweed, 3 parts of wormwood, 8 parts of dandelion, 3 parts of Viola yedoensis, 3 parts of liquorice, 5 parts of angelica, 10 parts of Millettia yunnanensis, 10 parts of panax ginseng, 5 parts of patrinia, 2 parts of aconite, 5 parts of coix seeds, 15 parts of prunella vulgaris, 10 parts of oldenlandia diffusa, 5 parts of barbata, 2 parts of lily, 5 parts of cypress, 3 parts of plantain, 4 parts of mulberry bark, 8 parts of scutellaria baicalensis, 8 parts of nightshade, 10 parts of agrimony 3 parts, 8 parts of creeping pot grass, 2 parts of lobelia, 10 parts of mulberry trees, 7 parts of astilbe, 6 parts of radix scutellariae, 5 parts of hawthorn, 2 parts of chicken's gizzard lining, 10 parts of roasted malt, 0.2 part of bear bile powder, 0.3 part of bezoars, 5 parts of turtle shells, 2 parts of tortoise shells, 0.8 part of centipede, 2 parts of scorpio, 1 part of scorpio, 1 part of mountain ridge, 2 parts of zedoaria, 4 parts of pollen, 6 parts of tiankui seeds, 10 parts of smilax china, 2 parts of turmeric, 4 parts of polyanthus polyphyllae.

[0084] Example 3

[0085] A pharmaceutical composition for treating liver cancer, the pharmaceutical composition is composed of the following raw materials in parts by weight:

[0086] 3 parts of red peony root, 1 part of sophora japonica, 10 parts of knotweed, 10 parts of wormwood, 10 parts of dandelion, 10 parts of viola yedoensis, 1 part of liquorice, 1 part of angelica, 2 parts of millet blood vine, 3 parts of cat ginseng, 10 parts of patrinia, 4 parts of aconite, 20 parts of coix seeds, 5 parts of selfheal, 3 parts of oldenlandia diffusa, 10 parts of barbata, 10 parts of lily, 2 parts of cypress, 5 parts of flatwood, 3 parts of mulberry bark, 10 parts of scutellaria, 3 parts of nightshade , 10 parts of herba agrimonii, 10 parts of scutellaria baicalensis, 2 parts of lobelia, 2 parts of mulberry, 3 parts of astilbe, 2 parts of radix scutellariae, 4 parts of hawthorn, 4 parts of chicken's gizzard lining, 6 parts of roasted malt, 0.3 parts of bear bile powder, 0.2 parts of bezoar, 3 parts of turtle shell, 2 parts of tortoise shell, 1 part of centipede, 1 part of dragon, 3 parts of scorpion, 6 parts of mountain ridge, 3 parts of curcuma, 5 parts of pollen, 2 parts of scutellaria baicalensis, 2 parts of scutellaria baicalensis, 3 parts of scutellaria baicalensis, 4 parts of red flower seeds.

[0087] In summary, the Chinese medicine composition for treating liver cancer proposed in the present invention improves the quality of life and survival period of patients by regulating the body's immune function, reducing the side effects of chemotherapy, inhibiting tumor growth, etc., and obtains an effect that is more beneficial to liver cancer patients, especially for liver cancer patients after radiotherapy, chemotherapy or surgery. It has an important effect on improving the body function, thereby solving the problem that patients will have more obvious side effects after radiotherapy, chemotherapy and surgery, such as loss of appetite, nausea and vomiting, diarrhea, abdominal pain, oral ulcers and other problems. Some patients will experience symptoms such as mental depression, fatigue, shortness of breath, and hair loss.

[0088] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A pharmaceutical composition for treating liver cancer, characterized in that: The pharmaceutical composition is composed of the following raw materials in parts by weight: 3-8 parts of red peony root, 1-3 parts of Sophora japonica, 3-10 parts of Polygonum cuspidatum, 3-10 parts of Artemisia capillaris, 3-10 parts of Taraxacum officinale, 3-10 parts of Viola yedoensis, 1-3 parts of Licorice, 1-5 parts of Angelica sinensis, 2-10 parts of Millettia yunnanensis, 3-10 parts of Panax notoginseng, 5-10 parts of Patrinia salsa, 1-5 parts of Aconite, 5-20 parts of Coix seeds, 3-20 parts of Prunella vulgaris, 3-20 parts of Hedyotis diffusa, 3-10 parts of Scutellaria barbata, 2-10 parts of Ipomoea batatas, 2-5 parts of Cypress on stone, 3-10 parts of Pinellia ternata, 2-4 parts of Morus alba, 2-10 parts of Lepidium officinale, 3-10 parts of Solanum nigrum, Crane 3-10 parts of grass, 3-10 parts of creeping pot grass, 2-5 parts of lobelia, 2-10 parts of mulberry, 3-9 parts of astilbe, 2-10 parts of root vegetable, 2-5 parts of hawthorn, 2-6 parts of chicken's gizzard lining, 3-10 parts of roasted malt, 0.1-0.3 parts of bear bile powder, 0.2-0.4 parts of bezoar, 2-5 parts of turtle shell, 2-5 parts of tortoise shell, 0.5-1 parts of centipede, 1-2 parts of dragon, 1-3 parts of scorpion, 1-6 parts of mountain ridge, 1-3 parts of curcuma, 2-5 parts of pollen, 2-10 parts of tiankui seeds, 2-10 parts of tribulus ternata, 1-3 parts of earthworm, and 3-5 parts of water safflower seeds.

2. A pharmaceutical composition for treating liver cancer according to claim 1, characterized in that: The pharmaceutical composition is composed of the following raw materials in parts by weight: 4 parts of red peony root, 2 parts of sophora japonica, 6 parts of knotweed, 10 parts of wormwood, 8 parts of dandelion, 5 parts of viola yedoensis, 1 part of licorice, 4 parts of angelica, 8 parts of millettia spatholobi, 7 parts of panax quinquefolius, 6 parts of patrinia herb, 3 parts of aconite, 15 parts of coix seeds, 18 parts of selfheal, 6 parts of oldenlandia diffusa, 4 parts of barbata, 6 parts of calamus, 2 parts of cyperus rotundus, 10 parts of cyperus rotundus, 2 parts of mulberry bark, and 10 parts of scutellaria baicalensis. 4 parts, 10 parts of Solanum nigrum, 8 parts of Agrimoniae, 5 parts of Herba Lycopodii, 2 parts of Herba Lobeliae, 4 parts of Cuscuta australis, 9 parts of Astilbe chinensis, 10 parts of Herba Lycopodii, 2 parts of Fructus Crataegi, 6 parts of Gallus gallbladder, 4 parts of Rhizoma Fructus Rhizoma, 0.1 parts of Bear Gall Powder, 0.4 parts of Calculus Bovis, 2 parts of Carapax Trichosanthis, 4 parts of Carapax Tortoise Shell, 0.5 parts of Scolopendra, 1 part of Dracaena, 1 part of Scorpio, 2 parts of Rhizoma Curcumae, 1 part of Pollen Typhae, 10 parts of Fructus Schizonepetae, 6 parts of Pleurotus eryngii, 1 part of Rhizoma Cynomorii, 3 parts of Fructus Polygoni Multiflori.

3. A pharmaceutical composition for treating liver cancer according to claim 1, characterized in that: The pharmaceutical composition is composed of the following raw materials in parts by weight: 8 parts of red peony root, 3 parts of sophora japonica, 3 parts of knotweed, 3 parts of wormwood, 8 parts of dandelion, 3 parts of viola yedoensis, 3 parts of licorice, 5 parts of angelica, 10 parts of millet spatholobi, 10 parts of cat ginseng, 5 parts of patrinia, 2 parts of aconite, 5 parts of coix seeds, 15 parts of selfheal, 10 parts of oldenlandia diffusa, 5 parts of barbata, 2 parts of calamus, 5 parts of cyperus rotundus, 3 parts of cyperus rotundus, 4 parts of mulberry bark, 10 parts of scutellaria baicalensis ... 8 parts, Solanum nigrum 8 parts, Herba Agrimoniae 3 parts, Herba Lycopodii 8 parts, Herba Lobeliae 2 parts, Cuscuta australis 10 parts, Astilbe 7 parts, Herba Glehniae 6 parts, Fructus Crataegi 5 parts, Gallus galli 2 parts, Roasted Malt 10 parts, Bear Bile Powder 0.2 part, Calculus Bovis 0.3 part, Carapax Trichosanthis 5 parts, Carapax Turtle 2 parts, Scolopendra 0.8 part, Dracaena 2 parts, Scorpio 1 part, Rhizoma Ceratitise 1 part, Rhizoma Curcumae 2 parts, Pollen Typhae 4 parts, Fructus Schizonepetae 6 parts, Psoralea corylifolia 10 parts, Rhizoma Cynomorii 2 parts, Fructus Polygoni Multiflori 4 parts.

4. A pharmaceutical composition for treating liver cancer according to claim 1, characterized in that: The pharmaceutical composition is composed of the following raw materials in parts by weight: 3 parts of red peony root, 1 part of sophora japonica, 10 parts of knotweed, 10 parts of wormwood, 10 parts of dandelion, 10 parts of viola yedoensis, 1 part of liquorice, 1 part of angelica sinensis, 2 parts of millettia spatholobi, 3 parts of panax quinquefolia, 10 parts of patrinia herb, 4 parts of aconite root, 20 parts of coix seeds, 5 parts of selfheal, 3 parts of oldenlandia diffusa, 10 parts of barbata, 10 parts of iris strychnifolia, 2 parts of cypress, 5 parts of spatholobi, 3 parts of mulberry bark, 10 parts of seeds of Lepidium, 3 parts of Solanum nigrum, 10 parts of Herba Agrimoniae, 10 parts of Herba Crepisae, 2 parts of Herba Lobeliae, 2 parts of Cuscuta australis, 3 parts of Astilbe, 2 parts of Herba Eupatorii, 4 parts of Fructus Crataegi, 4 parts of Endothelium of Chicken, 6 parts of Rhizoma Fructus Rhizoma, 0.3 parts of Bear Gallbladder Powder, 0.2 parts of Calculus Bovis, 3 parts of Carapax Trichosanthis, 2 parts of Carapax Tortoise Shell, 1 part of Scolopendra, 1 part of Dracaena, 3 parts of Scorpio, 6 parts of Rhizoma Ceratitise, 3 parts of Curcuma, 5 parts of Pollen Typhae, 2 parts of Fructus Schizonepetae, 2 parts of Psoralea corylifolia, 3 parts of Rhizoma Cyperi, 4 parts of Fructus Polygoni Multiflori.

5. A pharmaceutical composition for treating liver cancer according to claim 1, characterized in that: The pharmaceutical composition is prepared in the form of decoction, mixture, capsule, tablet, powder, pill, granule, atomizer, spray, fermentation agent, patch and liniment.

6. A pharmaceutical composition for treating liver cancer according to claim 5, characterized in that: The pharmaceutical composition is made into powder by crushing the pharmaceutical composition into powder by a pulverizer, and is made into capsules by filling the powder into capsules.

7. A pharmaceutical composition for treating liver cancer according to claim 5, characterized in that: The medicine composition is made into granules, and the medicine composition is formed into medicine granules through extraction, separation, concentration, drying and granulation processes. The medicine granules can be drunk after being brewed with hot water.

8. A pharmaceutical composition for treating liver cancer according to claim 5, characterized in that: When the pharmaceutical composition is made into tablets, the powder is used as the basis, starch and medicinal dextrin are added, and the tablets are made after solidification and drying.