An integrated equipment for pharmaceutical drug processing, fermentation and testing

Abstract

The present invention discloses an integrated device for processing, fermenting and detecting pharmaceutical drugs, which relates to the field of microbial fermentation technology. The device comprises a fermentation tank body, an inner wall of the fermentation tank body is provided with an internal heater, a discharge port is provided on one side of the fermentation tank body, a top cover is provided on the top of the fermentation tank body, an exhaust port is provided above one side of the fermentation tank body, and an exhaust pipe is fixedly installed on one side of the fermentation tank body and on the side of the exhaust port. The beneficial effects of the present invention are as follows: by adopting a passive collection structure, when in use, the internal air pressure of the fermentation tank body can be continuously increased to drive the pressurized piston to move to one side of the first outer mounting box, and trigger the upper and lower mounting racks located below to rotate, thereby moving the negative pressure gas storage pipe, so that the sampling mechanism can perform repeated sampling under the action of the internal air pressure of the fermentation tank body, and it is also convenient for subsequent staff to detect the composition of the exhaust gas during the fermentation process.

Description

Technical Field

[0001] The present invention relates to the technical field of microbial fermentation, and in particular to a pharmaceutical drug processing, fermentation and detection integrated equipment. Background Art

[0002] Drug processing is the process of processing and fermenting drug raw materials during drug production. Some drug raw materials need to be fermented to ensure that they can achieve better therapeutic effects when taken. Fermentation refers to the process of preparing microbial cells themselves or direct metabolites or secondary metabolites with the help of the life activities of microorganisms under aerobic or anaerobic conditions. Generally, the fermentation process needs to be set up in a relatively closed space, which can ensure the life activities of anaerobic bacteria and prevent the contamination of raw materials by miscellaneous bacteria. At the same time, the environmental data of the closed space can be controlled during drug processing for easy adjustment. During the fermentation of some raw materials, the activity of microorganisms will cause gas to be produced, thereby increasing the internal air pressure of the fermentation tank. The high air pressure will cause safety hazards. In addition, the gas composition produced during the fermentation process can well reflect the fermentation status of the current raw materials. The fermentation equipment currently used is not convenient for collecting this gas. For this reason, we propose a pharmaceutical drug processing, fermentation and detection integrated equipment. Summary of the Invention

[0003] In view of the shortcomings of the existing technology, the present invention provides an integrated pharmaceutical drug processing, fermentation and detection device, which solves the problems raised in the above background technology.

[0004] To achieve the above objectives, the present invention is implemented through the following technical solutions: a pharmaceutical drug processing, fermentation and detection integrated equipment, comprising a fermentation tank body, an inner wall of the fermentation tank body is provided with an internal heater, a discharge port is provided on one side of the fermentation tank body, a top cover is provided on the top of the fermentation tank body, an exhaust port is opened above one side of the fermentation tank body, an exhaust pipe is fixedly installed on one side of the fermentation tank body and on one side of the exhaust port, a sealing mechanism is provided inside the exhaust pipe, a first outer mounting box is fixedly installed on one side of the fermentation tank body, a first connecting plate is slidably connected to the interior of the fermentation tank body, one end of the first connecting plate extends to the interior of the first outer mounting box and is slidably connected thereto, the other end of the first connecting plate extends into the interior of the fermentation tank body and is fixedly installed with a pressure piston, an inner protective soft shell is fixedly installed on the inner wall of the fermentation tank body and on the outer side of the pressure piston, a pneumatic linkage mechanism is provided inside the first outer mounting box, and a sampling mechanism is provided on one side of the fermentation tank body;

[0005] The pneumatic linkage mechanism includes a first rack, which is fixedly mounted on one side of the first connecting plate. The first outer mounting box is internally rotatably connected to a first rotating shaft, a first gear is fixedly mounted on the outer side of the first rotating shaft, and a first trigger switch is fixedly mounted on one side of the inner wall of the first outer mounting box.

[0006] Preferably, a first inner slide groove is provided on the top of the inner wall of the first outer mounting box, a top reset mounting bar is fixedly installed on the top of the first connecting plate, a first inner slider is fixedly installed on the top of the top reset mounting bar, the first inner slider is inserted into the interior of the first inner slide groove and slidably connected thereto, a first spring is fixedly installed on the side of the top reset mounting bar close to the fermentation tank body, and the end of the first spring away from the top reset mounting bar is fixedly connected to the side wall of the fermentation tank body.

[0007] Preferably, the closing mechanism includes a first closing valve and a second closing valve, both of which are located inside the exhaust pipe and rotatably connected thereto. An upper gear box and a lower gear box are fixedly mounted at the top and bottom of the exhaust pipe, respectively. A third rack is slidably mounted inside the upper gear box. A fifth gear and a sixth gear are rotatably mounted inside the upper gear box. The fifth gear is fixedly connected to the first closing valve, and the sixth gear is connected to the second closing valve via a one-way bearing. The fifth gear and the sixth gear are both meshed with the third rack. A second rack is slidably mounted inside the lower gear box. An electric telescopic rod is fixedly mounted on one side of an inner wall of the lower gear box. The output end of the electric telescopic rod is fixedly connected to one side of the second rack. A third gear and a fourth gear are rotatably mounted on corresponding sides of the lower gear box. The third gear is fixedly connected to the first closing valve, and the fourth gear is connected to the second closing valve via a one-way bearing. A second rotating shaft is fixedly mounted on the top of the first rotating shaft. The top of the second rotating shaft penetrates into the interior of the lower gear box and is fixedly mounted with a second gear. The second, third, and fourth gears are all meshed with the second rack.

[0008] Preferably, the sampling mechanism includes a second outer mounting box, which is fixedly mounted on one side of the fermentation tank body, the bottom of the first rotating shaft passes through the first outer mounting box and is fixedly mounted with a connecting block, the bottom of the connecting block is mounted with a third rotating shaft through a one-way bearing, the bottom of the third rotating shaft extends to the interior of the second outer mounting box and is fixedly mounted with a gas storage tube placement rotating shaft, the gas storage tube placement rotating shaft is rotatably connected to the second outer mounting box, an upper placement rack and a lower placement rack are fixedly mounted on the outside of the gas storage tube placement rotating shaft, and a plurality of upper placement slots and lower placement slots are respectively provided inside the upper placement rack and on the top of the lower placement rack. The upper placement groove and the lower placement groove correspond to each other, and a negative pressure gas storage pipe is slidably placed inside the upper placement groove and the lower placement groove, and a second solenoid valve is provided inside the negative pressure gas storage pipe. A second trigger switch is fixedly installed on one side of the outer wall of the negative pressure gas storage pipe, and a sampling tube is installed on one side of the fermentation tank body and above the second outer installation box, one end of the sampling tube extends to the interior of the fermentation tank body, and a sampling groove is provided on the top of the second outer installation box, and the sampling groove is connected with the sampling tube, and a top trigger groove is provided on the top of the inner wall of the second outer installation box and below the sampling groove, and the negative pressure gas storage pipe cooperates with the top trigger groove.

[0009] Preferably, a top touch plate is slidably connected to the inside of the top triggering groove, a second connecting plate is fixedly installed on the top of the top touch plate, the second connecting plate passes through the top of the second outer mounting box and is fixedly installed with a fourth rack, an inner closed valve plate is provided inside the sampling tube, one side of the inner closed valve plate passes through the sampling tube and is fixedly installed with a seventh gear, the fourth rack is engaged with the seventh gear, a second spring is fixedly installed on the top of the top touch plate, and the top of the second spring is fixedly connected to the inner wall of the top triggering groove.

[0010] Preferably, a magnet body is embedded in the bottom of the negative pressure gas storage pipe, and an electromagnet is embedded inside the lower placement rack and below the lower placement slot. The negative pressure gas storage pipe is lifted upward by the repulsive force generated by the same magnetic poles after the magnet body and the electromagnet generate magnetic force.

[0011] Preferably, a bottom annular groove is provided at the bottom of the inner wall of the second outer mounting box, and a plurality of stabilizing sliders are fixedly installed at the bottom of the lower mounting rack. The stabilizing sliders are inserted into the bottom annular groove and slidably connected thereto, thereby increasing the stability of the lower mounting rack in rotating inside the second outer mounting box.

[0012] Preferably, a side discharge pipe is fixedly installed at the bottom of one side of the fermentation tank body, a bottom discharge pipe is opened at the bottom of the fermentation tank body, a discharge solenoid valve is fixedly installed at the bottom of the fermentation tank body and below the bottom discharge pipe, and a bracket is fixedly installed at the bottom of the fermentation tank body to facilitate the removal of materials inside the fermentation tank body.

[0013] Preferably, a placement opening is provided on one side of the second outer installation box, and a side closed door is connected to the inside of the placement opening by a hinge. The top of the second outer installation box and the top of the side closed door are provided with mutually cooperating buckles, and the negative pressure gas storage pipe inside the second outer installation box can be taken out when it is full.

[0014] The present invention provides a pharmaceutical drug processing, fermentation and detection integrated device, which has the following beneficial effects:

[0015] 1. The pharmaceutical drug processing, fermentation and testing integrated equipment adopts a passive collection structure. When in use, the internal air pressure of the fermentation tank body is continuously increased, thereby driving the pressurized piston to move toward one side of the first outer mounting box, and triggering the upper and lower placement racks located below to rotate, thereby moving the negative pressure gas storage pipe. At the same time, a reset mechanism is provided, so that the sampling mechanism can repeat sampling under the action of the internal air pressure of the fermentation tank body, and it is also convenient for subsequent staff to conduct detection based on the composition of the exhaust gas during the fermentation process.

[0016] 2. The pharmaceutical drug processing, fermentation and testing integrated equipment uses a double-layer blocking structure to seal the exhaust pipe. This structure can more conveniently control the air pressure inside the fermentation tank body in a linked manner. That is, when the air pressure reaches a predetermined value, active exhaust and pressure reduction work is performed, and the air pressure is re-sealed after it drops to the predetermined value, thereby eliminating the need for staff intervention during the process and making it more convenient to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the structure of the present invention;

[0018] Figure 2 For the present invention Figure 1 A magnified view of point A in the figure;

[0019] Figure 3 For the present invention Figure 1 Enlarged view of point B in FIG.

[0020] Figure 4 For the present invention Figure 1 Enlarged view of point C in the figure;

[0021] Figure 5 For the present invention Figure 1 The enlarged view of point D in the figure;

[0022] Figure 6 It is a structural schematic diagram of the closing mechanism of the present invention;

[0023] Figure 7 It is a motion diagram of the closing mechanism of the present invention.

[0024] In the figure: 1. fermenter body; 2. internal heater; 3. discharge port; 4. side discharge pipe; 5. bracket; 6. bottom discharge pipe; 7. discharge solenoid valve; 8. top cover; 9. exhaust port; 10. exhaust pipe; 11. first closing valve; 12. second closing valve; 13. inner protective soft shell; 14. first connecting plate; 15. pressure piston; 16. first rack; 17. first rotating shaft; 18. first gear; 19. top reset mounting strip; 20. first inner slide; 21. first inner slider; 22. first spring; 23. first outer mounting box; 24. first trigger switch; 25. second rotating shaft; 26. upper gear box; 27. lower gear box; 28. second gear; 29. ​​second rack; 30. third gear; 31. fourth gear 3. Gear; 32. Fifth gear; 33. Sixth gear; 34. Third rack; 35. Second outer mounting box; 36. Sampling tube; 37. Third rotating shaft; 38. Gas storage tube placement rotating shaft; 39. Upper placement rack; 40. Upper placement slot; 41. Lower placement rack; 42. Lower placement slot; 43. Negative pressure gas storage tube; 44. Second solenoid valve; 45. Second trigger switch; 46. Magnet body; 47. Electromagnet; 48. Top trigger slot; 49. Second connecting plate; 50. Top contact plate; 51. Second spring; 52. Fourth rack; 53. Inner closed valve plate; 54. Seventh gear; 55. Sampling slot; 56. Bottom annular groove; 57. Stabilizing slider; 58. Placement port; 59. Side closed door; 60. Connecting block; 61. Electric telescopic rod. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0026] See also Figures 1 to 7The present invention provides a technical solution: a pharmaceutical drug processing, fermentation and detection integrated equipment, including a fermentation tank body 1, a control box is provided on the outside of the fermentation tank body 1, an inner heater 2 is provided on the inner wall of the fermentation tank body 1, the temperature inside the fermentation tank body 1 can be regulated by the inner heater 2, and can be controlled by the control box, a discharge port 3 is provided on one side of the fermentation tank body 1, a top cover 8 is provided on the top of the fermentation tank body 1, an exhaust port 9 is opened above one side of the fermentation tank body 1, an exhaust pipe 10 is fixedly installed on one side of the fermentation tank body 1 and on one side of the exhaust port 9, a first outer installation box 23 is fixedly installed on one side of the fermentation tank body 1, and the inner The fermenter body 1 is slidably connected to a first connecting plate 14, one end of the first connecting plate 14 extends to the interior of the first outer mounting box 23 and is slidably connected thereto, the other end of the first connecting plate 14 extends to the interior of the fermenter body 1 and is fixedly mounted with a pressure piston 15, an inner protective soft shell 13 is fixedly mounted on the inner wall of the fermenter body 1 and on the outside of the pressure piston 15, a side discharge pipe 4 is fixedly mounted on the bottom of one side of the fermenter body 1, a bottom discharge pipe 6 is opened at the bottom of the fermenter body 1, a discharge solenoid valve 7 is fixedly mounted on the bottom of the fermenter body 1 and below the bottom discharge pipe 6, and a bracket 5 is fixedly mounted on the bottom of the fermenter body 1 to facilitate taking out the material inside the fermenter body 1;

[0027] A pneumatic linkage mechanism is provided inside the first outer mounting box 23, and the pneumatic linkage mechanism includes a first rack 16, the first rack 16 is fixedly mounted on one side of the first connecting plate 14, the first outer mounting box 23 is rotatably connected to the first rotating shaft 17, the outside of the first rotating shaft 17 is fixedly mounted with a first gear 18, a first trigger switch 24 is fixedly mounted on one side of the inner wall of the first outer mounting box 23, a first inner slide groove 20 is opened on the top of the inner wall of the first outer mounting box 23, a top reset mounting bar 19 is fixedly mounted on the top of the first connecting plate 14, a first inner slider 21 is fixedly mounted on the top of the top reset mounting bar 19, the first inner slider 21 is inserted into the interior of the first inner slide groove 20 and slidably connected thereto, a first spring 22 is fixedly mounted on the side of the top reset mounting bar 19 close to the fermentation tank body 1, and one end of the first spring 22 away from the top reset mounting bar 19 is fixedly connected to the side wall of the fermentation tank body 1.

[0028] The exhaust pipe 10 is provided with a closing mechanism inside, which includes a first closing valve 11 and a second closing valve 12. The first closing valve 11 and the second closing valve 12 are both located inside the exhaust pipe 10 and are rotatably connected thereto. An upper gear box 26 and a lower gear box 27 are fixedly mounted on the top and bottom of the exhaust pipe 10, respectively. A third rack 34 is slidably connected to the interior of the upper gear box 26. A fifth gear 32 and a sixth gear 33 are rotatably connected to the interior of the upper gear box 26. The fifth gear 32 is fixedly connected to the first closing valve 11, and the sixth gear 33 is connected to the second closing valve 12 through a one-way bearing. The fifth gear 32 and the sixth gear 33 are both meshed with the third rack 34. The interior of the lower gear box 27 A second rack 29 is slidably connected to it, and an electric telescopic rod 61 is fixedly installed on one side of the inner wall of the lower gear box 27. The output end of the electric telescopic rod 61 is fixedly connected to one side of the second rack 29. The corresponding two sides inside the lower gear box 27 are respectively rotatably connected with the third gear 30 and the fourth gear 31. The third gear 30 is fixedly connected to the first closing valve 11, and the fourth gear 31 is connected to the second closing valve 12 through a one-way bearing. The second rotating shaft 25 is fixedly installed on the top of the first rotating shaft 17. The top of the second rotating shaft 25 penetrates into the interior of the lower gear box 27 and is fixedly installed with the second gear 28. The second gear 28, the third gear 30 and the fourth gear 31 are all engaged with the second rack 29.

[0029] A sampling mechanism is provided on one side of the fermentation tank body 1. The sampling mechanism includes a second outer mounting box 35. The second outer mounting box 35 is fixedly mounted on one side of the fermentation tank body 1. The bottom of the first rotating shaft 17 passes through the first outer mounting box 23 and is fixedly mounted with a connecting block 60. The bottom of the connecting block 60 is mounted with a third rotating shaft 37 through a one-way bearing. The bottom of the third rotating shaft 37 extends to the interior of the second outer mounting box 35 and is fixedly mounted with a gas storage pipe placement rotating shaft 38. The gas storage pipe placement rotating shaft 38 is rotatably connected to the second outer mounting box 35. The outer side of the gas storage pipe placement rotating shaft 38 is fixedly mounted with an upper placement rack 39 and a lower placement rack 41. The upper placement rack 39 is fixedly mounted on the outer side of the gas storage pipe placement rotating shaft 38. 9 and the top of the lower placement rack 41 are respectively provided with a plurality of upper placement grooves 40 and lower placement grooves 42, the upper placement grooves 40 and the lower placement grooves 42 correspond to each other, and a negative pressure gas storage pipe 43 is slidably placed inside the upper placement grooves 40 and the lower placement grooves 42, and the bottom of the negative pressure gas storage pipe 43 is inlaid with a magnet body 46, and an electromagnet 47 is inlaid inside the lower placement rack 41 and below the lower placement groove 42. The repulsive force generated by the same magnetic poles after the magnet body 46 and the electromagnet 47 generate magnetic force pushes the negative pressure gas storage pipe 43 upward, and a second solenoid valve 44 is provided inside the negative pressure gas storage pipe 43, and a first solenoid valve 44 is fixedly installed on one side of the outer wall of the negative pressure gas storage pipe 43. A second trigger switch 45 is provided, a sampling tube 36 is installed on one side of the fermentation tank body 1 and above the second outer installation box 35, one end of the sampling tube 36 extends to the interior of the fermentation tank body 1, a sampling slot 55 is provided on the top of the second outer installation box 35, the sampling slot 55 is communicated with the sampling tube 36, a top triggering slot 48 is provided on the top of the inner wall of the second outer installation box 35 and below the sampling slot 55, the negative pressure gas storage pipe 43 cooperates with the top triggering slot 48, a top touch plate 50 is slidably connected to the inside of the top triggering slot 48, a second connecting plate 49 is fixedly installed on the top of the top touch plate 50, the second connecting plate 49 passes through the top of the second outer installation box 35 and is fixedly installed The fourth rack 52 and the sampling tube 36 are provided with an inner closed valve plate 53. One side of the inner closed valve plate 53 passes through the sampling tube 36 and is fixedly installed with a seventh gear 54. The fourth rack 52 is meshed with the seventh gear 54. The second spring 51 is fixedly installed on the top of the top contact plate 50. The top of the second spring 51 is fixedly connected to the inner wall of the top trigger groove 48. A bottom annular groove 56 is provided at the bottom of the inner wall of the second outer mounting box 35. A plurality of stabilizing sliders 57 are fixedly installed on the bottom of the lower placement rack 41. The stabilizing sliders 57 are inserted into the inside of the bottom annular groove 56 and are slidably connected thereto, thereby increasing the stability of the lower placement rack 41 in rotating inside the second outer mounting box 35.

[0030] A placement opening 58 is provided on one side of the second outer installation box 35, and a side closed door 59 is connected to the inside of the placement opening 58 by a hinge. The top of the second outer installation box 35 and the top of the side closed door 59 are provided with mutually cooperating buckles. When the negative pressure gas storage pipe 43 inside the second outer installation box 35 is full, it can be taken out.

[0031] In summary, when using the pharmaceutical drug processing, fermentation and detection integrated equipment, first place the chemical raw materials to be fermented inside the fermentation tank body 1, and close all the pipes until a closed space is formed. As the raw materials continue to ferment, the air pressure inside the fermentation tank body 1 continues to increase, and due to the increase in air pressure, the pressurized piston 15 moves toward the direction of the first outer mounting box 23, and the first connecting plate 14 also moves at the same time, and the first rack 16 and the first gear 18 are engaged, so that the first gear 18 rotates counterclockwise {all clockwise rotation directions in this application are from a top view angle, and the direction of the arrows set above the fourth gear 31 and the sixth gear 33 in the figure is this direction The direction of rotation is the direction set by the one-way bearing, that is, it does not drive the second closing valve 12 connected thereto to rotate}, and at the same time drives the second rotating shaft 25 and the second gear 28 to rotate counterclockwise, and at the same time drives the second rack 29 to move to the left. Since the second rack 29 is also engaged with the third gear 30 at this time, it will drive the third gear 30, the first closing valve 11 and the fifth gear 32 to rotate at the same time. Since the fifth gear 32 is engaged with the third rack 34, the third rack 34 also moves to the right. At this time, since the sixth gear 33 and the second closing valve 12 are connected by a one-way bearing, although the sixth gear 33 rotates, it will not affect the second closing valve 12. At this time, the shape is Figure 7 As shown in FIG2, as the internal air pressure of the fermentation tank body 1 increases again, the first rack 16 then moves toward the first outer mounting box 23, and causes the second rack 29 to continue to move under the influence of the second gear 28 and mesh with the fourth gear 31. At this time, since the fourth gear 31 and the second closing valve 12 are connected by a one-way bearing, the second closing valve 12 does not rotate, forming the following: Figure 7As shown in ③, when the internal equipment of the exhaust pipe 10 is started, the rotation of the first rotating shaft 17 will also drive the third rotating shaft 37 and the gas storage tube placement rotating shaft 38 to rotate, thereby driving the internal unused negative pressure gas storage tube 43 to move to the bottom of the top trigger groove 48 until the first rack 16 contacts the first trigger switch 24. At this time, the first trigger switch 24 is used to start the electromagnet 47, so that the electromagnet 47 generates a magnetic force, and the negative pressure gas storage tube 43 is driven by the principle that the magnetic poles of the electromagnet 47 and the magnet body 46 have the same magnetic poles to generate repulsion. The negative pressure gas storage pipe 43 is lifted upward, and at this time the second trigger switch 45 contacts the bottom of the second outer installation box 35, thereby starting the second solenoid valve 44, allowing the second solenoid valve 44 to open, and at this time, the upward lifting of the negative pressure gas storage pipe 43 is used to squeeze the top contact plate 50, causing the top contact plate 50 to move upward. At this time, the engagement of the fourth rack 52 and the seventh gear 54 is used to rotate the inner closed valve plate 53. At this time, the interior of the sampling tube 36 is connected, and the gas inside the fermentation tank body 1 will flow into the sampling tank 55 and the sampling tank 56 along the sampling tube 36. The top trigger groove 48 is touched, and the negative pressure gas storage pipe 43 with negative pressure inside is used to suck the gas into the negative pressure gas storage pipe 43. After the electromagnet 47 is powered for 2 seconds, the power is stopped. At this time, the gas sample in the negative pressure gas storage pipe 43 is collected, and the negative pressure gas storage pipe 43 falls due to the loss of repulsion, and the second solenoid valve 44 returns to the closed state to ensure the purity of the sample. The top touch plate 50 also falls due to the lack of bottom support, so that the inner closed valve plate 53 returns to the initial state again, closing the sampling tube 36, thus completing the collection of the gas sample. At the same time, the first rack 16 is also used to contact the first trigger switch 24 to start the electric telescopic rod 61, and the electric telescopic rod 61 is used to push the second rack 29 to the right. At this time, the engagement of the second rack 29 and the fourth gear 31 drives the fourth gear 31 to rotate, and the rotation of the fourth gear 31 will drive the second closing valve 12 to rotate, so that the interior of the exhaust pipe 10 is connected, and the excess gas can flow out along the exhaust pipe 10 to avoid the danger caused by high pressure, forming a Figure 7As shown in ④, as the internal air pressure of the fermentation tank body 1 decreases, the pressure on the pressurized piston 15 is gradually less than the pull given by the first spring 22, so that the first rack 16 moves toward the inside of the fermentation tank body 1, and at the same time, the electric telescopic rod 61 is in a standby state, passively extending and shortening with the movement of the second rack 29. At this time, the first gear 18 is reversed. Since the connecting block 60 is connected to the third rotating shaft 37 through a one-way bearing, this design can avoid the reversal of the rotating shaft 38 of the gas storage tube. When the first gear 18 When the gear 28 is reversed, the second gear 28 is also driven to reverse until the second rack 29 is meshed with the third gear 30 under the influence of the rotation of the second gear 28. At this time, the third gear 30 will simultaneously drive the first closing valve 11 and the fifth gear 32 to rotate under the influence of the second rack 29, thereby pulling the third rack 34 to the right. At this time, while driving the sixth gear 33 to rotate, the second closing valve 12 will also rotate along with the sixth gear 33, so that the first closing valve 11 and the second closing valve 12 are simultaneously rotated 90 degrees to achieve the effect of simultaneously closing the exhaust pipe 10, forming a shape as shown in the figure. Figure 7 As shown in ⑤, in this state, the interior of the fermentation tank body 1 is completely closed, and the air pressure continues to rise again, thereby achieving a cycle of the above steps. When the negative pressure gas storage pipe 43 located inside the second outer installation box 35 is completely used, the side closed door 59 is opened and the object is taken out from the interior of the second outer installation box 35, so that the gas generated by the fermentation situation in different time periods can be detected, thereby recording the fermentation situation.

[0032] The above description is only a preferred specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any technician familiar with the technical field, within the technical scope disclosed by the present invention, who makes equivalent replacements or changes based on the technical solution and inventive concept of the present invention, should be covered by the scope of protection of the present invention.

Claims

1. A pharmaceutical drug processing, fermentation and detection integrated equipment, comprising a fermentation tank body (1), characterized in that: The inner wall of the fermentation tank body (1) is provided with an internal heater (2), a discharge port (3) is provided on one side of the fermentation tank body (1), a top cover (8) is provided on the top of the fermentation tank body (1), an exhaust port (9) is provided above one side of the fermentation tank body (1), an exhaust pipe (10) is fixedly installed on one side of the fermentation tank body (1) and located on the side of the exhaust port (9), a sealing mechanism is provided inside the exhaust pipe (10), a first external installation box (23) is fixedly installed on one side of the fermentation tank body (1), and the fermentation tank body (1) A first connecting plate (14) is slidably connected to the interior of the fermenter body (1), one end of the first connecting plate (14) extends to the interior of the first external installation box (23) and is slidably connected thereto, the other end of the first connecting plate (14) extends to the interior of the fermenter body (1) and is fixedly mounted with a pressure piston (15), an inner protective soft shell (13) is fixedly mounted on the inner wall of the fermenter body (1) and on the outer side of the pressure piston (15), an air pressure linkage mechanism is provided inside the first external installation box (23), and a sampling mechanism is provided on one side of the fermenter body (1); The pneumatic linkage mechanism includes a first rack (16), the first rack (16) is fixedly mounted on one side of the first connecting plate (14), the first outer mounting box (23) is internally rotatably connected to a first rotating shaft (17), the outer side of the first rotating shaft (17) is fixedly mounted with a first gear (18), a first trigger switch (24) is fixedly mounted on one side of the inner wall of the first outer mounting box (23), a first inner slide groove (20) is provided at the top of the inner wall of the first outer mounting box (23), a top reset mounting bar (19) is fixedly mounted on the top of the first connecting plate (14), a first inner slider (21) is fixedly mounted on the top of the top reset mounting bar (19), the first inner slider (21) is inserted into the inside of the first inner slide groove (20) and is slidably connected thereto, a first spring (22) is fixedly mounted on the side of the top reset mounting bar (19) close to the fermentation tank body (1), and one end of the first spring (22) away from the top reset mounting bar (19) is fixedly connected to the side wall of the fermentation tank body (1); The sealing mechanism comprises a first sealing valve (11) and a second sealing valve (12), the first sealing valve (11) and the second sealing valve (12) are both located inside the exhaust pipe (10) and are rotatably connected thereto, an upper gear box (26) and a lower gear box (27) are fixedly mounted on the top and bottom of the exhaust pipe (10), respectively, a third rack (34) is slidably connected inside the upper gear box (26), a fifth gear (32) and a sixth gear (33) are rotatably connected inside the upper gear box (26), the fifth gear (32) is fixedly connected to the first sealing valve (11), the sixth gear (33) is connected to the second sealing valve (12) via a one-way bearing, the fifth gear (32) and the sixth gear (33) are both meshed with the third rack (34), the second gear box (27) is slidably connected inside A rack (29), an electric telescopic rod (61) is fixedly installed on one side of the inner wall of the lower gear box (27), and the output end of the electric telescopic rod (61) is fixedly connected to one side of the second rack (29). The corresponding two sides inside the lower gear box (27) are respectively rotatably connected to the third gear (30) and the fourth gear (31), the third gear (30) is fixedly connected to the first closing valve (11), and the fourth gear (31) is connected to the second closing valve (12) through a one-way bearing. The top of the first rotating shaft (17) is fixedly installed with the second rotating shaft (25), the top of the second rotating shaft (25) penetrates into the interior of the lower gear box (27) and is fixedly installed with the second gear (28), the second gear (28), the third gear (30) and the fourth gear (31) are all engaged with the second rack (29); The sampling mechanism includes a second outer mounting box (35), the second outer mounting box (35) is fixedly mounted on one side of the fermentation tank body (1), the bottom of the first rotating shaft (17) passes through the first outer mounting box (23) and is fixedly mounted with a connecting block (60), the bottom of the connecting block (60) is mounted with a third rotating shaft (37) through a one-way bearing, the bottom of the third rotating shaft (37) extends to the inside of the second outer mounting box (35) and is fixedly mounted with a gas storage pipe placement rotating shaft (38), the gas storage pipe placement rotating shaft (38) is rotatably connected to the second outer mounting box (35), an upper placement rack (39) and a lower placement rack (41) are fixedly mounted on the outside of the gas storage pipe placement rotating shaft (38), the interior of the upper placement rack (39) and the top of the lower placement rack (41) are respectively provided with a plurality of upper placement grooves (40) and lower placement grooves (42), the upper placement rack (39) and the top of the lower placement rack (41) are respectively provided with a plurality of upper placement grooves (40) and lower placement grooves (42), The groove (40) corresponds to the lower placement groove (42), and a negative pressure gas storage pipe (43) is slidably placed inside the upper placement groove (40) and the lower placement groove (42). A second solenoid valve (44) is provided inside the negative pressure gas storage pipe (43). A second trigger switch (45) is fixedly installed on one side of the outer wall of the negative pressure gas storage pipe (43). A sampling tube (36) is installed on one side of the fermentation tank body (1) and above the second outer installation box (35). One end of the sampling tube (36) extends to the inside of the fermentation tank body (1). A sampling groove (55) is opened on the top of the second outer installation box (35). The sampling groove (55) is communicated with the sampling tube (36). A top trigger groove (48) is opened on the top of the inner wall of the second outer installation box (35) and below the sampling groove (55). The negative pressure gas storage pipe (43) cooperates with the top trigger groove (48). The interior of the top triggering groove (48) is slidably connected with a top contact plate (50), the top of the top contact plate (50) is fixedly installed with a second connecting plate (49), the second connecting plate (49) passes through the top of the second outer installation box (35) and is fixedly installed with a fourth rack (52), the interior of the sampling tube (36) is provided with an inner closed valve plate (53), one side of the inner closed valve plate (53) passes through the sampling tube (36) and is fixedly installed with a seventh gear (54), the fourth rack (52) is engaged with the seventh gear (54), the top of the top contact plate (50) is fixedly installed with a second spring (51), the top of the second spring (51) is fixedly connected to the inner wall of the top triggering groove (48).

2. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 1, characterized in that: The bottom of the negative pressure gas storage pipe (43) is inlaid with a magnet body (46), and the interior of the lower placement frame (41) and below the lower placement groove (42) is inlaid with an electromagnet (47).

3. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 1, characterized in that: A bottom annular groove (56) is provided at the bottom of the inner wall of the second outer installation box (35), and a plurality of stabilizing slide blocks (57) are fixedly installed at the bottom of the lower placement rack (41). The stabilizing slide blocks (57) are inserted into the bottom annular groove (56) and are slidably connected thereto.

4. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 1, characterized in that: A side discharge pipe (4) is fixedly installed at the bottom of one side of the fermentation tank body (1), a bottom discharge pipe (6) is opened at the bottom of the fermentation tank body (1), a discharge solenoid valve (7) is fixedly installed at the bottom of the fermentation tank body (1) and below the bottom discharge pipe (6), and a bracket (5) is fixedly installed at the bottom of the fermentation tank body (1).

5. The pharmaceutical drug processing, fermentation and detection integrated equipment according to claim 1, characterized in that: A placement opening (58) is provided on one side of the second outer installation box (35), and a side closed door (59) is rotatably connected to the inside of the placement opening (58) via a hinge. Mutually matching buckles are provided on the top of the second outer installation box (35) and the top of the side closed door (59).

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