A method and system for detecting polio vaccine spin plunger pump filling hang-up

Abstract

The application discloses a method and system for detecting poliomyelitis vaccine rotary plunger pump filling hanging liquid, relates to the technical field of poliomyelitis vaccine detection, and comprises a model construction end, a simulation tracking end and a hanging liquid correction end.The model construction end is used for constructing a filling model, and an M199 solution and a 2-phenoxyethanol mixed solution are used to simulate poliomyelitis vaccine stock solution.The simulation tracking end is used for tracking the up-down movement and rotary movement of the plunger pump in real time, and tracking the relative movement between a needle and a pre-charged syringe in real time.The hanging liquid correction end is used for obtaining the best correction point of the plunger pump filling hanging liquid by judging the best point abnormality.The method and system for detecting poliomyelitis vaccine rotary plunger pump filling hanging liquid optimally solve the hanging liquid problem of the rotary plunger pump when the rotary plunger pump is used for dispensing poliomyelitis vaccine, and can judge whether the best point of detection appears angle abnormality in real time, so that the safety and reliability of the detection of poliomyelitis vaccine rotary plunger pump filling hanging liquid are ensured.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of detecting polio vaccine, and particularly relates to a method for detecting polio vaccine rotary plunger pump filling hanging liquid and a system thereof. BACKGROUND

[0002] The large stroke movement of the plunger pump simulates the vaccine dispensing process, mainly through the reciprocating movement of the plunger in the cylinder to realize the suction and discharge of the liquid medicine, so as to complete the accurate dispensing of the vaccine. When the plunger pump moves outward, the pressure in the working cavity is reduced, and the rotation of the pump rod triggers the opening of the inlet valve and the closing of the outlet valve, and the liquid medicine is sucked into the cavity. When the plunger pump is pushed inward, the pressure in the working cavity is increased, and the pump rod is rotated, the outlet valve is opened, and the inlet valve is closed, and the liquid medicine is discharged and enters the filling container.

[0003] At present, for the polio vaccine dispensing line, we choose the rotary plunger pump for filling. However, from 2019 to 2022, the phenomenon of pre-charged syringe rubber plug hanging liquid frequently occurred, which led to a high probability of hanging liquid phenomenon during the dispensing of polio vaccine, reduced the yield of the product, and to some extent, weakened the safety of the vaccine.

[0004] Therefore, the present application provides a method for detecting polio vaccine rotary plunger pump filling hanging liquid and a system thereof to solve the above problems. SUMMARY

[0005] The main purpose of the present application is to provide a method for detecting polio vaccine rotary plunger pump filling hanging liquid and a system thereof to solve the problems raised in the above background.

[0006] To achieve the above purpose, the technical scheme adopted by the present application is as follows: a method for detecting polio vaccine rotary plunger pump filling hanging liquid and a system thereof, comprising a model construction end, a simulation tracking end and a hanging liquid correction end.

[0007] The model construction end is used to construct a filling model, simulate the vaccine dispensing process by using the large stroke movement of the plunger pump, and repeatedly train and reproduce the hanging liquid phenomenon to obtain a model for detecting polio vaccine rotary plunger pump filling hanging liquid by using M199 solution and 2-phenoxyethanol mixed liquid to simulate polio vaccine stock solution.

[0008] The simulation tracking end is used to track the up-down movement and rotation movement of the plunger pump in real time, and track the relative movement between the needle and the pre-charged syringe in real time, and timely judge whether the current time vaccine stock solution training simulation is abnormal.

[0009] The hanging liquid correction end is used for judging the best point exception, and real-time detection and analysis of the hanging liquid problem, obtaining the best correction point of the plunger pump filling hanging liquid, and automatically correcting the parameters of the up and down movement and rotation movement angle of the plunger pump corresponding to the best correction point and the coordinated pump movement of the filling needle, to ensure the accuracy of the detection of polio vaccine.

[0010] The model building end includes a filling model module, a mixing simulation module and a movement setting module.

[0011] The filling model module includes a model building unit and a polio vaccine liquid unit.

[0012] The model building unit is used to build a rotary plunger pump filling model and set basic parameters of the rotary plunger pump filling, including rotation angle, best detection point and rotation time length.

[0013] The polio vaccine liquid unit is used to mix M199 solution with 2-phenoxyethanol to obtain simulated polio vaccine stock solution.

[0014] The mixing simulation module includes a mixing homogenate unit and a parameter setting unit.

[0015] The mixing homogenate unit is used to drive the stirring son in the vaccine liquid to rotate at high speed by a magnetic stirrer with a rotating magnetic field, to obtain mixed and uniform polio vaccine stock solution.

[0016] The parameter setting unit is used to set standard parameters of the best detection of the rotary plunger pump filling hanging liquid of polio vaccine, including sealing parameters of the plunger pump, output flow parameters of the plunger pump, output pressure parameters of the plunger pump, coordinated parameters of the plunger pump movement and needle movement, rotation angle of the plunger pump, best detection point of the plunger pump and rotation time length of the plunger pump.

[0017] The movement setting module includes a vaccine sub-packaging unit and a sub-packaging tracking unit.

[0018] The vaccine sub-packaging unit is used to sub-package the simulated polio vaccine stock solution into different volumes, and to fill and detect the hanging liquid of the simulated polio vaccine stock solution with different volumes.

[0019] The sub-packaging tracking unit is used to track the detection results of the vaccine stock solution filling hanging liquid in real time through a data tracking instrument.

[0020] The simulation tracking end includes a movement monitoring module, a needle movement module and a simulation judgment module.

[0021] The movement monitoring module includes an up and down monitoring unit and a rotation monitoring unit.

[0022] The up-down monitoring unit is used for capturing the optimal detection point of the simulated polio vaccine bulk filling hanging liquid by the camera in real time, generating a picture from the image captured by the camera, comparing the detection point in the picture with the optimal detection point in real time, and determining whether the optimal detection point is abnormal, specifically as follows.

[0023] The optimal detection point of the simulated polio vaccine bulk filling hanging liquid is compared with the detection point in the picture, and the comparison formula is as follows.

[0024]

[0025] Wherein, P n represents the comparison value, U1 represents the position of the optimal detection point of the simulated polio vaccine bulk filling hanging liquid at the corresponding time, U2 represents the position of the detection point in the picture at the corresponding time, x represents the detection power consumption of the tracked detection point in the picture, and X represents the detection power consumption of the position of the optimal detection point of the simulated polio vaccine bulk filling hanging liquid at the corresponding time.

[0026] Step II: If the calculated P n is equal to 0, it is determined that the tracked detection point position is executed normally, and if P n is not equal to 0, it is determined that the tracked detection point position is executed abnormally.

[0027] The rotation monitoring unit is used for monitoring the rotation angle and rotation time length of the plunger pump in real time, and calculating whether the rotation angle of the plunger pump deviates in real time, and the calculation method is as follows.

[0028] The rotation center point of the plunger pump is set as the origin, and the coordinate system is established, and the rotation angle vector of the plunger pump during rotation is obtained from the calculation formula.

[0029]

[0030] Wherein, α is the included angle between the plunger pump rotation distance and the positive direction of the X axis, θ is the included angle between the plunger pump rotation distance and the positive direction of the Y axis, A is the plunger pump height, Δx is the rotation angle vector of the plunger pump in the X axis direction during rotation, and Δy is the rotation angle vector of the plunger pump in the Y axis direction during rotation.

[0031] The calculated plunger pump rotation angle vectors Δx and Δy are differentially calculated with the standard rotation angle of the plunger pump, the standard deviation is set as O and M, if Δx-O≥1 or Δy-M≥1, it is judged that the rotation angle of the plunger pump is abnormal, and if not, it is judged that the rotation angle of the plunger pump is normal.

[0032] The needle movement module includes a relative motion unit, an optimal parameter unit and a difference calculation unit.

[0033] The relative motion unit is used for calculating the deviation vector of the rotation angle of the plunger pump at the current time and the rotation angle of the plunger pump at the historical time through a formula for calculating whether the rotation angle of the plunger pump deviates, and if the calculated rotation direction vector is positive, it indicates that the rotation direction of the plunger pump is normal, and if the calculated rotation direction vector is negative or 0, it indicates that the rotation direction of the plunger pump is abnormal, and the system reports a voice prompt;

[0034] The optimal parameter unit is used for setting the optimal parameter value of the relative motion between the needle and the pre-charged syringe.

[0035] The difference calculation unit is used for calculating the deviation value of the relative motion between the needle and the pre-charged syringe through a formula for calculating whether the rotation angle of the plunger pump deviates.

[0036] The simulation judgment module includes a simulation early warning unit, which is used for indicating normal when the rotation angle deviation value of the plunger pump is equal to 0, and indicating abnormal when the rotation angle deviation value of the plunger pump is not equal to 0, and the system reports a voice alarm.

[0037] The hanging liquid correction end includes a data receiving module, a hanging liquid detection module, a difference correction module and a correction monitoring module.

[0038] The data receiving module is used for receiving the filling hanging liquid result of the simulated polio vaccine stock solution in real time through a data receiver.

[0039] The hanging liquid detection module is used for real-time analysis and detection of the optimal parameters of the poliomyelitis vaccine rotary plunger pump filling according to the filling hanging liquid result.

[0040] The difference correction module is used for correcting the rotation angle of the plunger pump and the detection point in real time according to the calculated rotation angle vector, and the correction value is determined according to the calculated value.

[0041] The correction monitoring module includes a correction self-tracking unit and a hanging liquid tracking recording unit.

[0042] The correction self-tracking unit is used for receiving the rotation angle vector of the rotation motion angle in real time through a data tracking instrument, receiving the rotation angle vector after the correction value, and calculating the difference value of the front and rear rotation angle vectors, if the difference value is equal to 0, it indicates that the plunger pump rotation correction is invalid, the system reports and corrects again, and if the difference value is not equal to 0, it indicates that the plunger pump rotation correction is effective.

[0043] The hanging liquid tracking recording unit is used for recording the rotary plunger pump filling hanging liquid parameters obtained by repeated simulation in real time through a data tracking instrument, calculating the average value of the parameters, and obtaining the optimal optimization parameters of the detection poliomyelitis vaccine rotary plunger pump filling.

[0044] A method for detecting the hanging liquid of polio vaccine rotary plunger pump filling, comprising the following steps:

[0045] Step one: enter the model building end, build the filling model, use M199 solution and 2-phenoxy ethanol mixed solution to simulate polio vaccine stock solution, use the large stroke movement of the plunger pump to simulate the vaccine dispensing process, and reproduce the hanging liquid phenomenon through multiple superimposed training;

[0046] Step two: enter the simulation tracking end, track the up-down movement and rotary movement of the plunger pump in real time, and track the relative movement between the needle and the pre-charged syringe in real time to judge the simulation anomaly;

[0047] Step three: enter the hanging liquid correction end, simulate the vaccine dispensing process through large stroke movement, and timely correct the up-down movement and rotary movement of the plunger pump corresponding to the best point according to the judged best point anomaly, to ensure the accuracy of detecting polio vaccine.

[0048] The present application has the following beneficial effects:

[0049] 1. In the present application, when detecting the hanging liquid of polio vaccine rotary plunger pump filling, the filling model is built, the large stroke movement of the plunger pump is used to simulate the vaccine dispensing process, and the hanging liquid phenomenon is reproduced through multiple superimposed training, which optimizes the solution to the hanging liquid problem of the rotary plunger pump during dispensing polio vaccine, helps to improve the yield of the product, and to a certain extent, enhances the safety of the vaccine.

[0050] 2. In the present application, when detecting the hanging liquid of polio vaccine rotary plunger pump filling, the relative movement between the needle and the pre-charged syringe is tracked in real time to judge whether the vaccine stock solution training simulation is abnormal, so that the best point of detection can be judged in real time whether the angle is abnormal during the detection of polio vaccine rotary plunger pump filling, further ensuring the stability and accuracy of the detection of polio vaccine rotary movement.

[0051] 3. In the present application, when detecting the hanging liquid of polio vaccine rotary plunger pump filling, the best point anomaly is judged, and the up-down movement and rotary movement of the plunger pump corresponding to the best point are timely corrected, which further increases the accuracy of detecting polio vaccine, and ensures the safety and reliability of detecting the hanging liquid of polio vaccine rotary plunger pump filling. BRIEF DESCRIPTION OF DRAWINGS

[0052] Figure 1 The system architecture schematic diagram of the present application, a method for detecting the hanging liquid of polio vaccine rotary plunger pump filling and its system;

[0053] Figure 2It is a kind of detection polio vaccine rotating plunger pump filling hanging liquid method and its system's construction model end's framework schematic diagram of the present application;

[0054] Figure 3 It is a kind of detection polio vaccine rotating plunger pump filling hanging liquid method and its system's simulation tracking end's framework schematic diagram of the present application;

[0055] Figure 4 It is a kind of detection polio vaccine rotating plunger pump filling hanging liquid method and its system's hanging liquid correction end's framework schematic diagram. DETAILED DESCRIPTION

[0056] To make the technical means, creative features, purposes and effects of the present application easy to understand, the present application will be further described below in conjunction with specific embodiments.

[0057] Embodiment one

[0058] Please refer to Figures 1-2 It is a kind of detection polio vaccine rotating plunger pump filling hanging liquid method and its system, including construction model end, simulation tracking end and hanging liquid correction end;

[0059] The construction model end is used for constructing filling model, and using M199 solution and 2-phenoxyethanol mixed solution to simulate polio vaccine stock solution, using large stroke movement of plunger pump to simulate vaccine dispensing process, repeatedly training to reproduce hanging liquid phenomenon, obtaining detection polio vaccine rotating plunger pump filling hanging liquid model;

[0060] The simulation tracking end is used for real-time tracking of up-down movement and rotation movement of plunger pump, and real-time tracking of relative movement between needle and pre-charged syringe, timely judging whether the current time training simulation of vaccine stock solution is abnormal or not;

[0061] The hanging liquid correction end is used for judging the best point abnormality, and real-time detecting and analyzing hanging liquid problem, obtaining the best correction point of plunger pump filling hanging liquid, automatically correcting the up-down movement and rotation movement angle of plunger pump corresponding to the best correction point and the parameters of filling needle cooperating with pump movement according to the best correction point, ensuring the accuracy of detecting polio vaccine, and the parameters of filling needle cooperating with pump movement specifically refer to height.

[0062] The construction model end includes filling model module, mixed simulation module and movement setting module;

[0063] The filling model module includes model construction unit and polio vaccine liquid unit;

[0064] The model construction unit is used for constructing rotating plunger pump filling model, and setting basic parameters of rotating plunger pump filling, and the basic parameters include rotation angle, best detection point and rotation time length.

[0065] The polio vaccine liquid unit is used for mixing M199 solution with 2-phenoxyethanol to obtain a simulated polio vaccine stock solution, the M199 solution and the 2-phenoxyethanol mixture are used to simulate the polio vaccine stock solution, the large stroke movement of the plunger pump is used to simulate the vaccine dispensing process, and different dispensing amounts of the vaccine stock solution are set, and the liquid hanging phenomenon is reproduced through multiple superimposed training.

[0066] The mixing simulation module comprises a mixing and uniforming liquid unit and a parameter setting unit;

[0067] The mixing and uniforming liquid unit is used for driving the stirring rod to rotate at high speed in the vaccine liquid by the magnetic stirrer driven by the rotating magnetic field, so as to obtain the mixed and uniform polio vaccine stock solution;

[0068] The parameter setting unit is used for setting the standard parameters for detecting the liquid hanging of the polio vaccine rotary plunger pump, and the parameters comprise sealing parameters of the plunger pump, output flow parameters of the plunger pump, output pressure parameters of the plunger pump, plunger pump movement and needle movement coordination parameters, rotation angle of the plunger pump, optimal detection point of the plunger pump and rotation time length of the plunger pump, and the plunger pump movement and needle movement coordination parameters specifically refer to noise parameters of the plunger pump and plunger pump temperature rise parameters.

[0069] The movement setting module comprises a vaccine dispensing unit and a dispensing tracking unit;

[0070] The vaccine dispensing unit is used for dispensing the simulated polio vaccine stock solution into different volumes, and dispensing the simulated polio vaccine stock solution with different volumes for liquid hanging detection;

[0071] The dispensing tracking unit is used for tracking the detection results of the vaccine stock solution liquid hanging in real time through a data tracking instrument, optimizing the liquid hanging problem of the rotary plunger pump when dispensing the polio vaccine, helping to improve the yield of the product, and at the same time, enhancing the safety of the vaccine to a certain extent.

[0072] Embodiment two

[0073] Please refer to Figure 3 Based on the basis of embodiment one, the simulation tracking end comprises a movement monitoring module, a needle movement module and a simulation judgment module;

[0074] The movement monitoring module comprises an up-down monitoring unit and a rotation monitoring unit;

[0075] The up-down monitoring unit is used for capturing the optimal detection point of the simulated polio vaccine stock solution liquid hanging in real time through a camera, generating a picture from the image captured by the camera, comparing the detection point in the picture with the optimal detection point in real time, and determining whether the optimal detection point is abnormal, specifically:

[0076] The best detection point of the simulated polio vaccine stock solution filling hanging liquid is compared with the detection point in the picture, and the comparison formula is as follows:

[0077]

[0078] Wherein, P n represents the comparison value, U1 represents the position of the best detection point of the simulated polio vaccine stock solution filling hanging liquid at the corresponding time, U2 represents the position of the detection point in the picture at the corresponding time, x represents the detection power consumption of the tracked detection point in the picture, and X represents the detection power consumption of the position of the best detection point of the simulated polio vaccine stock solution filling hanging liquid at the corresponding time. The power consumption here refers to the detection power consumption in the process of filling the simulated polio vaccine stock solution;

[0079] Step II: If the calculated P n is equal to 0, it is determined that the tracked detection point position is executed normally, and if P n is not equal to 0, it is determined that the tracked detection point position is executed abnormally;

[0080] The rotation monitoring unit is used to monitor the rotation angle and rotation time length of the plunger pump in real time through the camera, and to calculate in real time whether the rotation angle of the plunger pump deviates, and the calculation method is as follows:

[0081] The rotation center point of the plunger pump is set as the origin, and the coordinate system is established, and the rotation angle vector of the plunger pump during rotation is obtained from the calculation formula:

[0082]

[0083] Wherein, α is the included angle between the plunger pump rotation distance and the positive direction of the X axis, θ is the included angle between the plunger pump rotation distance and the positive direction of the Y axis, A is the plunger pump height, Δx is the rotation angle vector of the plunger pump in the X axis direction during rotation, and Δy is the rotation angle vector of the plunger pump in the Y axis direction during rotation;

[0084] The calculated plunger pump rotation angle vectors Δx and Δy are difference calculated with the standard rotation angle of the plunger pump, and the standard difference is set as O and M. If Δx-O≥1 or Δy-M≥1, it is judged that the rotation angle of the plunger pump is abnormal, and if not, it is judged that the rotation angle of the plunger pump is normal. By tracking the up-down movement and rotation movement of the plunger pump in real time, and tracking the relative movement between the needle and the pre-filled syringe in real time, it is determined whether the vaccine stock solution training simulation is abnormal.

[0085] The needle movement module includes a relative motion unit, a best parameter unit and a difference calculation unit;

[0086] The relative motion unit is used to calculate the deviation vector of the plunger pump rotation angle at the current time and the plunger pump rotation angle at the historical time through the formula for calculating whether the rotation angle of the plunger pump deviates, and the specific formula is as follows:

[0087] The position of the plunger pump is set as the origin, a coordinate system is established, and the rotation direction vector of the plunger pump during rotation is obtained from a calculation formula:

[0088]

[0089] wherein, alpha is the angle between the rotation direction distance of the plunger pump and the positive direction of the X axis, theta is the angle between the rotation direction distance of the plunger pump and the positive direction of the Y axis, A is the height of the plunger pump, Delta x is the rotation direction vector of the plunger pump in the X axis direction during rotation, and Delta y is the rotation direction vector of the plunger pump in the Y axis direction during rotation; if the calculated Delta x and Delta y rotation direction vectors are positive numbers, it indicates that the rotation direction of the plunger pump is normal, and if the calculated rotation direction vectors are negative numbers or 0, it indicates that the rotation direction of the plunger pump is abnormal, and the system issues a voice reminder;

[0090] The optimal parameter unit is used to set the optimal parameter value of the relative movement between the needle and the pre-charged syringe;

[0091] The difference calculation unit is used to calculate the deviation value of the relative movement between the needle and the pre-charged syringe through a formula for calculating whether the rotation angle of the plunger pump deviates, specifically as follows:

[0092] The center points of the needle and the pre-charged syringe are set as the origin, a coordinate system is established, and the relative movement vector between the needle and the pre-charged syringe is obtained from a calculation formula:

[0093]

[0094] wherein, alpha is the angle between the relative movement distance between the needle and the pre-charged syringe and the positive direction of the X axis, theta is the angle between the relative movement distance between the needle and the pre-charged syringe and the positive direction of the Y axis, A is the height of the needle and the pre-charged syringe, Delta x is the relative movement vector of the needle and the pre-charged syringe in the X axis direction, and Delta y is the relative movement vector of the needle and the pre-charged syringe in the Y axis direction;

[0095] The calculated relative movement vectors Delta x and Delta y of the needle and the pre-charged syringe are difference calculated with the standard relative movement of the needle and the pre-charged syringe, the standard difference value is set as O and M, if Delta x-O >= 1 or Delta y-M >= 1, it is judged that the relative movement of the needle and the pre-charged syringe is abnormal, and if not, it is judged that the relative movement of the needle and the pre-charged syringe is normal.

[0096] The simulation judgment module includes a simulation early warning unit, the simulation early warning unit is used to indicate normal when the rotation angle deviation value of the plunger pump is equal to 0, and abnormal when the rotation angle deviation value of the plunger pump is not equal to 0, the system issues a voice alarm, which can judge whether the optimal point of detection has an angle abnormality in real time, further ensuring the stability and accuracy of detecting the rotational movement of polio vaccine.

[0097] Embodiment Three

[0098] Please refer to Figure 4 Based on the basis of Embodiment One, the hanging liquid correction end includes a data receiving module, a hanging liquid detection module, a difference correction module and a correction monitoring module.

[0099] The data receiving module is used to receive the filling hanging liquid result of the analog polio vaccine stock solution in real time through the data receiver.

[0100] The hanging liquid detection module is used to analyze and detect the best parameters of the polio vaccine rotary plunger pump filling in real time according to the filling hanging liquid result.

[0101] The difference correction module is used to correct the rotation angle of the plunger pump and the detection point in real time according to the calculated rotation angle vector, and the correction value is determined according to the calculated value. Through the judgment of the best point exception, the best correction point of the plunger pump filling hanging liquid is obtained through real-time detection and analysis of the hanging liquid problem, and the accuracy of setting the best parameters of the polio vaccine rotary plunger pump filling is ensured.

[0102] The correction monitoring module includes a correction self-tracking unit and a hanging liquid tracking recording unit.

[0103] The correction self-tracking unit is used to receive the rotation angle vector of the rotation motion angle in real time through the data tracking instrument, and receive the rotation angle vector after the correction value, and calculate the difference value of the front and rear rotation angle vectors. If the difference value is equal to 0, it means that the plunger pump rotation correction is invalid, and the system will be recalculated and corrected. If the difference value is not equal to 0, it means that the plunger pump rotation correction is effective.

[0104] The hanging liquid tracking recording unit is used to record the rotary plunger pump filling hanging liquid parameters obtained by repeated simulation in real time through the data tracking instrument, and calculate the average value of the parameters to obtain the best optimization parameters of the polio vaccine rotary plunger pump filling hanging liquid. Through timely correction of the up and down motion and rotation motion of the plunger pump corresponding to the best point, the accuracy of detecting polio vaccine is further increased, and the safety and reliability of detecting polio vaccine rotary plunger pump filling hanging liquid are ensured.

[0105] The application discloses a method and system for detecting liquid hanging of poliomyelitis vaccine rotary plunger pump filling, and the system comprises the following steps.

[0106] A method for detecting liquid hanging of poliomyelitis vaccine rotary plunger pump filling comprises the following steps.

[0107] Step one: entering the model construction end, constructing the filling model, adopting M199 solution and 2-phenoxy ethanol mixed solution to simulate poliomyelitis vaccine stock solution, and utilizing large stroke movement of the plunger pump to simulate the vaccine dispensing process, and reproducing the liquid hanging phenomenon through multiple superimposed training.

[0108] Step two: entering the simulation tracking end, judging simulation abnormality by tracking the up-down movement and rotation movement of the plunger pump in real time, and tracking the relative movement between the needle and the pre-charged syringe in real time.

[0109] Step three: entering the liquid hanging correction end, simulating the vaccine dispensing process through large stroke movement, correcting the up-down movement and rotation movement of the plunger pump corresponding to the best point in time according to the best point abnormality, and guaranteeing the accuracy of the poliomyelitis vaccine detection.

[0110] The foregoing is considered as illustrative only of the principles of the application. Further, since numerous modifications and changes will readily occur to those skilled in the art, it is not desired to limit the application to the exact construction and practice described. Accordingly, all such variations and modifications are intended to be included within the scope of the application as defined in the following claims and the equivalents thereof.

Claims

1. A system for detecting the filling and dispensing of polio vaccine using a rotary plunger pump, characterized in that, The system includes a model building terminal, a simulation tracking terminal, and an infusion correction terminal; The construction model is used to construct a filling model and use a mixture of M199 solution and 2 phenoxyethanol to simulate the original polio vaccine solution. The large stroke motion of the plunger pump is used to simulate the vaccine dispensing process. The liquid hanging phenomenon is reproduced through multiple superimposed training to obtain a rotary plunger pump filling and liquid hanging model for detecting polio vaccine. The simulation tracking terminal is used to promptly determine whether the vaccine stock training simulation being tested at the current moment is abnormal by tracking the up-and-down and rotational movements of the plunger pump in real time, as well as the relative movement between the needle and the pre-filled syringe in real time. The infusion correction end is used to detect and analyze infusion problems in real time by judging the optimal point of abnormality, and to obtain the optimal correction point for the plunger pump to fill the infusion. Based on the optimal correction point, the plunger pump's up-and-down movement and rotation angle and height corresponding to the optimal correction point are automatically corrected to ensure the accuracy of polio vaccine detection. The model construction module includes a filling model module, a hybrid simulation module, and a motion setting module; The filling model module includes a model building unit and a polio vaccine liquid unit; The model building unit is used to build a rotary plunger pump filling model and set the basic parameters of rotary plunger pump filling, including rotation angle, optimal detection point and rotation time. The polio vaccine liquid unit is used to mix M199 solution with 2 phenoxyethanol to obtain a simulated polio vaccine stock solution; The mixing simulation module includes a mixing homogenization unit and a parameter setting unit; The mixing and homogenizing unit is used to drive a rotating magnetic field through a magnetic stirrer to make the stir bar rotate at high speed in the vaccine liquid, so as to obtain a uniformly mixed polio vaccine stock solution. The parameter setting unit is used to set the standard parameters for optimal detection of polio vaccine filling and infusion using a rotary plunger pump. The parameters include the plunger pump's sealing parameters, output flow rate parameters, output pressure parameters, noise parameters, temperature rise parameters, rotation angle, optimal detection point, and rotation duration. The motion setting module includes a vaccine dispensing unit and a dispensing tracking unit; The vaccine dispensing unit is used to dispense the simulated polio vaccine stock solution into different weights, and to fill and test the simulated polio vaccine stock solution of different weights. The dispensing and tracking unit is used to track the test results of vaccine concentrate filling and infusion in real time using a data tracker.

2. The system according to claim 1, characterized in that: The simulated tracking terminal includes a motion monitoring module, a needle motion module, and a simulation judgment module; The motion monitoring module includes an up-down monitoring unit and a rotation monitoring unit; The upper and lower monitoring units are used to capture the optimal detection points for simulated polio vaccine bulk solution filling and infusion in real time using a camera. The captured images are generated into pictures, and the detection points in the pictures are compared with the optimal detection points in real time to determine whether the optimal detection points are abnormal. Specifically: The optimal detection point for simulating polio vaccine bulk filling and infusion is compared with the detection point in the image. The comparison formula is as follows: in, Indicates the comparison value. This indicates the optimal testing point for simulating the filling and infusion of polio vaccine concentrate at the corresponding time. This represents the detection point in the image at the corresponding time. This represents the power consumption of the detection points in the tracked image. This represents the power consumption at the optimal detection point for simulating the filling and infusion of polio vaccine concentrate at the corresponding time. Step II: If the calculated If the value is 0, the tracked detection point is considered to have performed normally. If the value is not equal to 0, the tracked detection point is considered to be performing abnormally; The rotation monitoring unit is used to monitor the rotation angle and rotation duration of the plunger pump in real time via a camera, and to calculate in real time whether the rotation angle of the plunger pump deviates. The calculation method is as follows: Establish a coordinate system with the rotation center point of the plunger pump as the origin, and calculate the rotation angle vector of the plunger pump using the formula: in, The angle between the piston pump's rotational distance and the positive X-axis direction is denoted as . Let A be the angle between the piston pump's rotation distance and the positive Y-axis, and let A be the piston pump height. This is the rotation angle vector of the plunger pump as it rotates along the X-axis. This is the rotation angle vector of the plunger pump when it rotates in the Y-axis direction; Calculated piston pump rotation angle vector and The difference between the standard rotation angle and the standard rotation angle of the plunger pump is calculated, and the standard difference is set as O and M. -O≥1 or If -M≥1, the rotation angle of the plunger pump is considered abnormal; otherwise, the rotation angle of the plunger pump is considered normal.

3. The system according to claim 2, characterized in that: The needle motion module includes a relative motion unit, an optimal parameter unit, and a difference calculation unit; The relative motion unit is used to calculate the deviation vector between the current rotation angle of the plunger pump and the rotation angle of the plunger pump at a historical time by using a formula to calculate whether the rotation angle of the plunger pump deviates. If the calculated deviation vector is positive, it means that the rotation direction of the plunger pump is normal. If the calculated deviation vector is negative or 0, it means that the rotation direction of the plunger pump is abnormal, and the system will issue a voice reminder. The optimal parameter unit is used to set the optimal parameter values ​​for the relative speed and height of the needle and the pre-filled syringe. The difference calculation unit is used to calculate the deviation of the relative speed and height between the needle and the pre-filled syringe three times by using a formula to calculate whether the rotation angle of the plunger pump deviates.

4. The system according to claim 3, characterized in that: The simulation judgment module includes a simulation early warning unit. The simulation early warning unit is used to indicate normal operation when the rotation angle deviation of the plunger pump is equal to 0, and to indicate abnormal operation when the rotation angle deviation of the plunger pump is not equal to 0, and to report to the system to issue a voice alarm.

5. The system according to claim 1, characterized in that: The infusion correction terminal includes a data receiving module, an infusion detection module, a difference correction module, and a correction monitoring module; The data receiving module is used to receive the filling and dispensing results of the simulated polio vaccine stock solution in real time through the data receiver; The infusion detection module is used to analyze and detect the optimal parameters for rotary plunger pump filling of polio vaccine in real time based on the filling infusion results. The difference correction module is used to correct the rotation angle and detection point of the plunger pump in real time according to the calculated rotation angle vector, and the correction value is determined according to the calculated value.

6. The system according to claim 5, characterized in that: The correction monitoring module includes a correction self-tracking unit and an infusion tracking and recording unit; The self-tracking correction unit is used to receive the rotation angle vector of the rotational motion angle in real time through the data tracker, and receive the rotation angle vector after correction. It calculates the difference between the front and back rotation angle vectors. If the difference is equal to 0, it means that the piston pump rotation correction is invalid and reports to the system to recalculate and correct. If the difference is not equal to 0, it means that the piston pump rotation correction is valid. The infusion tracking and recording unit is used to record the parameters of the rotary plunger pump filling infusion obtained from repeated simulations in real time through a data tracker, and calculate the average value of the parameters to obtain the optimal parameters for detecting the rotary plunger pump filling infusion of polio vaccine.

7. A method for detecting polio vaccine infusion via rotary plunger pump filling, comprising a system for detecting polio vaccine infusion via rotary plunger pump filling according to any one of claims 1-6, characterized in that, Includes the following steps: Step 1: Enter the model construction end, construct the filling model, use the M199 solution and 2 phenoxyethanol mixture to simulate the polio vaccine stock solution, and use the large stroke motion of the plunger pump to simulate the vaccine filling process. Repeated training to reproduce the liquid hanging phenomenon. Step 2: Enter the simulation tracking terminal and judge the simulation abnormality by tracking the up-and-down and rotational movements of the plunger pump in real time, as well as the relative movement between the needle and the pre-filled syringe in real time; Step 3: Enter the infusion correction end, simulate the vaccine dispensing process through large stroke motion, and promptly correct the up-and-down and rotational movements of the plunger pump corresponding to the optimal point based on the judgment of abnormality, so as to ensure the accuracy of polio vaccine detection.

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