A microenvironment detection device for biological toxicology research and methods of use thereof

The pressure relief, sealing and ventilation mechanism driven by double threaded rods solves the problem of experimental errors caused by increased air pressure in biotoxicology research, achieves stable air pressure and toxic gas sealing, and ensures the accuracy of experimental data and the monitoring of biophysiological parameters.

CN119573812BActive Publication Date: 2025-10-17FOURTH MILITARY MEDICAL UNIVERSITY
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Patent Information

Application Number
CN202411778827.5
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-12-05
Publication Date
2025-10-17
Estimated Expiration
2044-12-05

AI Technical Summary

Technical Problem

In biotoxicology research, since the organisms in the device need oxygen to survive, the input of fresh air leads to an increase in the volatile gases of the poison, resulting in an increase in air pressure, which affects the accuracy of sensor detection and experimental errors.

Method used

The pressure relief mechanism, sealing mechanism, ventilation mechanism and closing mechanism are driven by double threaded rods. Through the cooperation of pressure relief spring, sealing spring and neutralization solution, stable air pressure is maintained to prevent toxic gas leakage and dust entry, thus ensuring the accuracy of oxygen supply and experimental data.

Benefits of technology

It effectively maintains a stable air pressure in the test chamber, prevents toxic gas leakage, ensures the accuracy of experimental data, provides real-time monitoring of biological and physiological parameters, and studies the effects of poisons on organisms.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present application relates to the technical fields of plant toxicology microenvironment detection, and discloses a microenvironment detection device for biological toxicology research and a use method thereof, which comprises a detection box, a double-threaded rod rotatably installed in the detection box, the double-threaded rod penetrating through the detection box, a driving motor fixedly installed on the right side of the detection box, an output shaft of the driving motor fixedly connected with the right end of the double-threaded rod, and a plurality of driving plates fixedly installed on the outer wall of the double-threaded rod, further comprising a pressure relief mechanism, which comprises an L-shaped transmission plate slidingly installed on the left inner wall of the detection box and extending to the inside of the detection box at the right end of the L-shaped transmission plate. After the driving plate leaves the L-shaped transmission plate, the pressure relief plate will push the mixed gas of the pressure relief box into the neutralizing solution in the neutralizing tank from the gas conveying pipe under the elastic force of the pressure relief spring, so as to maintain stable air pressure and avoid the continuous input of air to cause the air pressure in the detection box to rise and affect the accuracy of the experiment.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of plant toxicology microenvironment detection equipment, in particular to a microenvironment detection device for biological toxicology research and a use method thereof. BACKGROUND

[0002] The device is designed for studying and evaluating the response and changes of organisms exposed to harmful substances under specific environmental conditions. The device integrates multiple sensing technologies and can accurately monitor multiple key parameters in the experimental environment, such as temperature, humidity, gas concentration, pH value, oxygen content, and light intensity. It provides necessary environmental data for toxicology research. Through real-time monitoring of the microenvironment, researchers can better understand the influence of environmental factors on the toxicological response of organisms.

[0003] During the research experiment, the organisms inside the device need oxygen to survive. In the process of continuously inputting fresh air, the toxic gas and air will continuously increase. At this time, the air pressure in the device will continuously increase. The high-pressure environment is not conducive to the detection of sensors during the experiment, which will increase the distortion of experimental analysis and produce experimental errors. SUMMARY

[0004] The purpose of the present application is to provide a microenvironment detection device for biological toxicology research and a use method thereof, to solve the problem that in the process of research experiment, the organisms inside the device need oxygen to survive, in the process of continuously inputting fresh air, the toxic gas and air will continuously increase, at this time, the air pressure in the device will continuously increase, the high-pressure environment is not conducive to the detection of sensors during the experiment, which will increase the distortion of experimental analysis and produce experimental errors.

[0005] To solve the above technical problems, the present application is realized by the following technical scheme:

[0006] The present application is a microenvironment detection device for biological toxicology research, which comprises a detection box, a double-threaded rod rotatably installed in the detection box, the double-threaded rod penetrating the detection box, a drive motor fixedly installed on the right side of the detection box, the output shaft of the drive motor fixedly connected with the right end of the double-threaded rod, and a plurality of drive plates fixedly installed on the outer wall of the double-threaded rod.

[0007] The pressure relief mechanism comprises an L-shaped transmission plate slidingly installed on the left side inner wall of the detection box, the right end of the L-shaped transmission plate extends into the detection box, a fixed plate is fixedly sleeved on the L-shaped transmission plate, a pressure relief spring is sleeved on the L-shaped transmission plate, the left end of the pressure relief spring is fixedly connected with the fixed plate, the right end of the pressure relief spring is fixedly connected with the detection box, a pressure relief tank is fixedly installed on the left side inner wall of the detection box, air inlet grooves are formed in the top and bottom of the pressure relief tank respectively, a push plate is fixedly installed on the left side of the L-shaped transmission plate, the left end of the push plate extends into the pressure relief tank and is slidingly connected with the pressure relief tank, a pressure relief plate is fixedly installed on the left end of the push plate, the pressure relief plate is slidingly connected with the pressure relief tank, a neutralization tank is fixedly installed on the left side of the detection box, a gas conveying pipe is fixedly installed on the right side inner wall of the neutralization tank, and the gas conveying pipe is communicated with the pressure relief tank.

[0008] Further, the neutralization tank is provided with a sealing mechanism, the sealing mechanism comprises a slotted cylinder fixedly installed on the left side of the neutralization tank, the right end of the slotted cylinder extends into the neutralization tank, a T-shaped hollow circular plate is slidingly installed in the slotted cylinder, the left end of the T-shaped hollow circular plate extends out of the slotted cylinder, a sealing spring is fixedly installed on the right side of the T-shaped hollow circular plate, the right end of the sealing spring is fixedly connected with the right side inner wall of the slotted cylinder, and a plurality of air outlet holes are formed in the outer wall of the T-shaped hollow circular plate.

[0009] Further, the front of the detection box is fixedly provided with two strip-shaped plates, a T-shaped square rod is slidingly installed on each of the two strip-shaped plates, the two T-shaped square rods respectively penetrate through the two strip-shaped plates, a limiting spring is sleeved on each of the two T-shaped square rods, one end of each of the two limiting springs away from each other is fixedly connected with the T-shaped square rod, one end of each of the two limiting springs close to each other is fixedly connected with the strip-shaped plate, and a trapezoidal plate is fixedly installed at the end of each of the two T-shaped square rods away from each other, a sealing plate is slidingly installed on the front of the detection box, and the back surface of each of the two trapezoidal plates is connected with the sealing plate.

[0010] Further, the top of the detection box is provided with an air exchange mechanism, the air exchange mechanism comprises a hemispherical filter plate fixedly installed on the top of the detection box, a bellows is fixedly installed on the top inner wall of the detection box, a double screw rod penetrates through the bellows and is rotationally connected with the bellows, a plurality of fan blades are fixedly installed on the outer wall of the double screw rod, a plurality of air outlet circular holes are formed in the left side of the bellows, an air inlet L-shaped pipe is fixedly installed on the right side of the bellows, and the top end of the air inlet L-shaped pipe is communicated with the hemispherical filter plate.

[0011] Further, the detection box is provided with two movable mechanisms, the movable mechanism comprises a sliding rod fixedly installed on the left inner wall of the detection box, the right end of the sliding rod is fixedly connected with the wind box, a circular ring block is fixedly sleeved on the sliding rod, the detection box is provided with an annular adaptive block, the left end of the circular ring block is fixedly installed with a movable spring, the left end of the movable spring is fixedly connected with the annular adaptive block, and an inner threaded block is threadedly sleeved on the double-threaded rod.

[0012] Further, the sliding rod penetrates through the inner threaded block and is in sliding connection with the inner threaded block, a U-shaped limiting plate is fixedly installed on the top inner wall of the detection box, a T-shaped sliding plate is slidably installed in the U-shaped limiting plate, the T-shaped sliding plate penetrates through the U-shaped limiting plate and is in sliding connection with the U-shaped limiting plate, and a connecting plate is hingedly installed at the bottom end of the inner threaded block and is hingedly connected with the T-shaped sliding plate.

[0013] Further, the detection box is provided with a closing mechanism, the closing mechanism comprises a sealing box arranged in the bottom groove in the detection box, the sealing box is provided with a poison, two rectangular sliding grooves are formed in the sealing box, and a rectangular sliding plate is slidably installed in each of the two rectangular sliding grooves, a plurality of ventilation grooves are formed in the right side and the left side of the sealing box, the plurality of ventilation grooves penetrate through the two rectangular sliding grooves, limit rectangular plates one are fixedly installed on the sides away from each other of the two rectangular sliding plates, one ends of the two limit rectangular plates one away from each other extend out of the two rectangular sliding grooves, limit rectangular plates two are fixedly installed on the left side and the right side of the sealing box, two closing springs are fixedly installed on the top of the two limit rectangular plates two, and the top ends of the two closing springs are fixedly connected with the two limit rectangular plates one.

[0014] Further, the method of the micro-environment detection device for biological toxicology research comprises the following steps:

[0015] S1: guarantee the air pressure in the device;

[0016] S2: oxygen supply to ensure the survival of organisms;

[0017] S3: flexible sealing of toxic gas;

[0018] S4: prevent dust from neutralizing the solution.

[0019] The present application has the following beneficial effects:

[0020] (1) The micro-environment detection device for biological toxicology research, in the process of rotating the double screw rod, drives a plurality of driving plates to rotate, the driving plates contact the L-shaped transmission plate in the process of rotating, the L-shaped transmission plate moves to the direction close to the detection box under the action of the inclined surface, at this time, the pressure relief spring is compressed, the L-shaped transmission plate drives the push plate to move, the push plate drives the pressure relief plate to move, after the pressure relief plate passes through the air inlet groove, the mixed gas in the detection box enters the pressure relief tank, after the driving plate leaves the L-shaped transmission plate, the pressure relief plate pushes the mixed gas in the pressure relief tank to the neutralizing solution in the neutralizing tank through the gas pipe under the elastic force of the pressure relief spring, so that the stable air pressure is maintained to avoid the continuous input of air causing the air pressure in the detection box to rise and affecting the accuracy of the experiment;

[0021] (2) The micro-environment detection device for biological toxicology research, after the sealed box is placed in the designated groove in the detection box, the sealing plate is closed, the sealing plate moves away from the sealing plate when contacting the two trapezoidal plates, at this time, the limit spring is compressed, after the sealing plate is closed, the trapezoidal plate resets under the elastic force of the limit spring, at this time, the back of the trapezoidal plate is tightly attached to the front of the sealing plate to ensure the sealing of the detection box, avoiding the leakage of toxic gas in the detection box affecting the health of the staff, then the driving motor is started, the driving motor drives the double screw rod to rotate, the double screw rod drives a plurality of fan blades to rotate, the fan blades generate suction force, the suction force sucks the air outside into the detection box through the air inlet L-shaped pipe and the hemispherical filter plate, so as to ensure the normal supply of oxygen in the detection box, avoid the death of the organisms in the detection box due to lack of oxygen for a long time, and effectively prevent the dust and impurities outside from entering the detection box;

[0022] (3) The micro-environment detection device for biological toxicology research, in the process of rotating the double screw rod, the two inner threaded blocks are brought close to each other, the inner threaded blocks drive the connecting plate to move, the connecting plate drives the T-shaped slide plate to descend, the T-shaped slide plate contacts the limit rectangular plate and drives the limit rectangular plate to descend in the process of descending, the limit rectangular plate one drives the rectangular slide plate to descend, at this time, the closing spring is compressed, at this time, the descending rectangular slide plate opens a plurality of ventilation grooves, at this time, the toxicant volatilizes and emits toxic gas for experiment, after the experiment is finished, the T-shaped slide plate leaves the limit rectangular plate one, and the sealing box is sealed again under the elastic force of the closing spring, preventing the leakage of toxic gas and improving the flexibility of the device;

[0023] (4)The microenvironment detection device for biological toxicology research, mixed gas containing toxic gas is input into the neutralization tank, if the toxic gas is alkaline, the neutralization solution is acidic, if the toxic gas is acidic, the neutralization solution is alkaline, water and some harmless gas are generated after the reaction of the toxic gas and the solution, as the gas in the neutralization tank becomes more and more, the gas enters the grooved cylinder through the hole on the grooved cylinder, the T-shaped hollow circular plate is moved away from the detection tank, at this time, the sealing spring is stretched, when the air outlet hole on the T-shaped hollow circular plate leaves the grooved cylinder, the gas is discharged from the sealing spring, when the gas pressure in the neutralization tank is low, the sealing property of the grooved cylinder is ensured under the elastic force of the sealing spring, so that the dust and gas outside are prevented from entering the neutralization tank and affecting the reaction of the neutralization solution and the toxic gas, the temperature sensor can detect the body temperature change of the biological during a long experimental process, which has important significance for studying the influence of the toxicant on the metabolism of the biological, because the change of the metabolism rate often leads to the fluctuation of the body temperature, the heart rate sensor can measure the heart rate of the animal, so as to understand whether the toxicant affects the function of the cardiovascular system, and the respiration sensor can monitor the respiration frequency and depth of the biological, so as to reflect the effect of the toxicant on the respiratory system.

[0024] Of course, it is not necessary for any product implementing the present application to achieve all the advantages mentioned above. BRIEF DESCRIPTION OF DRAWINGS

[0025] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed for the embodiment description will be briefly introduced as follows. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can also be obtained by those skilled in the art without creative effort.

[0026] Figure 1 It is a schematic diagram of the overall structure of the present application;

[0027] Figure 2 It is a schematic diagram of the front cross-sectional structure of the present application;

[0028] Figure 3 It is a schematic diagram of the enlarged structure of the present application Figure 2 A;

[0029] Figure 4 It is a schematic diagram of the internal partial cross-sectional structure of the present application;

[0030] Figure 5 It is a schematic diagram of the enlarged structure of the present application Figure 2 B;

[0031] Figure 6 It is a schematic diagram of the internal partial cross-sectional structure of the present application;

[0032] Figure 7 The application Figure 6 amplification structure of C in the application is shown in the figure.

[0033] Figure 8 The application

[0034] In the drawings, the components represented by each reference numeral are listed as follows:

[0035] In the figure: 1, detection box; 2, double-threaded rod; 3, driving motor; 4, driving plate; 5, pressure relief mechanism; 501, L-shaped transmission plate; 502, fixed plate; 503, pressure relief spring; 504, pressure relief box; 505, air inlet groove; 506, push plate; 507, pressure relief plate; 508, neutralization box; 509, air conveying pipe; 6, sealing mechanism; 601, slotted cylinder; 602, T-shaped hollow circular plate; 603, sealing spring; 604, air outlet hole; 605, strip plate; 606, T-shaped rod; 607, limiting spring; 608, trapezoidal plate; 609, sealing plate; 7, air exchange mechanism; 701, hemispherical filter plate; 702, bellows; 703, fan blade; 704, air outlet circular hole; 705, air inlet L-shaped pipe; 8, movable mechanism; 800, sliding rod; 801, circular ring block; 802, annular adaptive block; 803, movable spring; 804, internally threaded block; 805, T-shaped limiting plate; 806, T-shaped sliding plate; 807, connecting plate; 9, closing mechanism; 901, sealing box; 902, poison; 903, rectangular sliding groove; 904, rectangular sliding plate; 905, ventilation groove; 906, limiting rectangular plate one; 907, limiting rectangular plate two; 908, closing spring. DETAILED DESCRIPTION

[0036] The technical solutions in the embodiments of the application will be clearly and completely described below with reference to the drawings in the embodiments of the application. Obviously, the described embodiments are only part of the embodiments of the application, rather than all the embodiments of the application. Based on the embodiments in the application, all other embodiments obtained by a person of ordinary skill in the art without creative work fall within the protection scope of the application.

[0037] Please refer to Figure 1 - Figure 8 As shown in the figure, the application is a micro-environment detection device for biological toxicology research, which comprises a detection box 1, a double-threaded rod 2 rotatably installed in the detection box 1, the double-threaded rod 2 penetrating through the detection box 1, a driving motor 3 fixedly installed on the right side of the detection box 1, the output shaft of the driving motor 3 being fixedly connected with the right end of the double-threaded rod 2, and a plurality of driving plates 4 fixedly installed on the outer wall of the double-threaded rod 2.

[0038] The pressure release mechanism 5 includes an L-shaped transmission plate 501 slidably mounted on the left inner wall of the detection box 1. The right end of the L-shaped transmission plate 501 extends into the detection box 1. A fixed plate 502 is fixedly sleeved on the L-shaped transmission plate 501. A pressure release spring 503 is sleeved on the L-shaped transmission plate 501. The left end of the pressure release spring 503 is fixedly connected to the fixed plate 502. The right end of the pressure release spring 503 is fixedly connected to the detection box 1. A pressure release box 504 is fixedly mounted on the left inner wall of the detection box 1. The pressure release box 504 is fixedly mounted on the left inner wall of the detection box 1. Air inlet grooves 505 are respectively provided at the top and bottom. A push plate 506 is fixedly installed on the left side of the L-shaped transmission plate 501. The left end of the push plate 506 extends into the pressure relief box 504 and is slidably connected to the pressure relief box 504. A pressure relief plate 507 is fixedly installed on the left end of the push plate 506. The pressure relief plate 507 is slidably connected to the pressure relief box 504. A neutralization box 508 is fixedly installed on the left side of the detection box 1. An air supply pipe 509 is fixedly installed on the right inner wall of the neutralization box 508, and the air supply pipe 509 is communicated with the pressure relief box 504.

[0039] like Figure 3 As shown, a sealing mechanism 6 is provided on the neutralization box 508, and the sealing mechanism 6 includes a grooved cylinder 601 fixedly installed on the left side of the neutralization box 508, the right end of the grooved cylinder 601 extends into the neutralization box 508, a T-shaped hollow circular plate 602 is slidably installed in the grooved cylinder 601, the left end of the T-shaped hollow circular plate 602 extends to the outside of the grooved cylinder 601, a sealing spring 603 is fixedly installed on the right side of the T-shaped hollow circular plate 602, the right end of the sealing spring 603 is fixedly connected to the right inner wall of the grooved cylinder 601, and a plurality of air outlet holes 604 are opened on the outer wall of the T-shaped hollow circular plate 602.

[0040] The gas will enter the grooved cylinder 601 through the holes on the grooved cylinder 601, and the gas will push the T-shaped hollow circular plate 602 to move away from the detection box 1. At this time, the sealing spring 603 is stretched and deformed. When the air outlet 604 on the T-shaped hollow circular plate 602 leaves the grooved cylinder 601, the gas will be discharged from the sealing spring 603. When the air pressure in the neutralization box 508 is low, the elastic force of the sealing spring 603 will ensure the sealing of the grooved cylinder 601, preventing external dust and gas from entering the neutralization box 508 and affecting the reaction between the neutralization solution and the poisonous gas.

[0041] like Figure 1As shown, the front of the detection box 1 is fixedly installed with two strip-shaped plates 605, two T-shaped bars 606 are slidably installed on the two strip-shaped plates 605 respectively, the two T-shaped bars 606 penetrate through the two strip-shaped plates 605 respectively, two limit springs 607 are sleeved on the two T-shaped bars 606 respectively, the ends of the two limit springs 607 away from each other are fixedly connected with the two T-shaped bars 606 respectively, the ends of the two limit springs 607 close to each other are fixedly connected with the two strip-shaped plates 605 respectively, and the ends of the two T-shaped bars 606 away from each other are fixedly installed with two trapezoidal plates 608 respectively. The front of the detection box 1 is slidably installed with a sealing plate 609, and the back of the two trapezoidal plates 608 is in contact with the sealing plate 609.

[0042] After the sealing box 901 is placed in the designated groove in the detection box 1, the sealing plate 609 is closed, and when the sealing plate 609 contacts the two trapezoidal plates 608, the sealing plate 609 moves away from the sealing plate 609. At this time, the limit spring 607 is compressed and deformed, and after the sealing plate 609 is closed, the trapezoidal plate 608 is reset under the elastic force of the limit spring 607. At this time, the back of the trapezoidal plate 608 is tightly attached to the front of the sealing plate 609 to ensure the sealing of the detection box 1, so as to avoid the leakage of toxic gas in the detection box 1 affecting the health of the staff.

[0043] As shown in the figure, Figure 5 The top of the detection box 1 is provided with a ventilation mechanism 7, the ventilation mechanism 7 comprises a hemispherical filter plate 701 fixedly installed on the top of the detection box 1, a bellows 702 fixedly installed on the inner wall of the top of the detection box 1, a double-thread rod 2 penetrating through the bellows 702 and rotatably connected with the bellows 702, a plurality of fan blades 703 fixedly installed on the outer wall of the double-thread rod 2, a plurality of air outlet round holes 704 formed on the left side of the bellows 702, and an air inlet L-shaped pipe 705 fixedly installed on the right side of the bellows 702 and in communication with the hemispherical filter plate 701.

[0044] The double-thread rod 2 drives the plurality of fan blades 703 to rotate, and the fan blades 703 generate suction force. The suction force can suck air from the outside into the detection box 1 through the air inlet L-shaped pipe 705 and the hemispherical filter plate 701, so as to ensure the normal supply of oxygen in the detection box 1, avoid the death of organisms in the detection box 1 due to lack of oxygen caused by long-term experiment, and effectively prevent dust and impurities from entering the detection box 1.

[0045] As shown in the figure, Figure 6As shown, two movable mechanisms 8 are arranged in the detection box 1, the movable mechanism 8 comprises a sliding rod 800 fixedly installed on the inner wall of the left side of the detection box 1, the right end of the sliding rod 800 is fixedly connected with the air bellow 702, a circular ring block 801 is fixedly sleeved on the sliding rod 800, an annular adaptive block 802 is arranged in the detection box 1, the left end of the circular ring block 801 is fixedly installed with a movable spring 803, the left end of the movable spring 803 is fixedly connected with the annular adaptive block 802, and an inner threaded block 804 is threadedly sleeved on the double-threaded rod 2.

[0046] In the process of approaching of the inner threaded blocks 804, the annular adaptive block 802 is contacted and pushed to move, at this time, the movable spring 803 is compressed and deformed, after the inner threaded blocks 804 are away from the threads on the double-threaded rod 2, the annular adaptive block 802 is abutted against the inner threaded blocks 804 by the elastic force of the movable spring 803, at this time, the inner threaded blocks 804 are in a semi-detached threaded state, thereby ensuring the stability of the inner threaded blocks 804 and the normal volatilization of the toxic gas.

[0047] As shown in the figure, Figure 6 The sliding rod 800 penetrates through the inner threaded block 804 and is in sliding connection with the inner threaded block 804, a T-shaped sliding plate 806 is slidingly installed in the top inner wall of the detection box 1, the T-shaped sliding plate 806 penetrates through the T-shaped limiting plate 805 and is in sliding connection with the T-shaped limiting plate 805, a connecting plate 807 is hingedly installed at the bottom end of the inner threaded block 804, and the bottom end of the connecting plate 807 is hingedly connected with the T-shaped sliding plate 806.

[0048] In the process of rotating of the double-threaded rod 2, the two inner threaded blocks 804 are approached to each other, the inner threaded blocks 804 drive the connecting plate 807 to move, and the connecting plate 807 drives the T-shaped sliding plate 806 to descend.

[0049] As shown in the figure, Figure 6 and Figure 7 As shown in the figure, a closing mechanism 9 is arranged in the detection box 1, the closing mechanism 9 comprises a sealing box 901 arranged in the inner bottom groove of the detection box 1, a toxic substance 902 is arranged in the sealing box 901, two rectangular sliding grooves 903 are formed in the sealing box 901, two rectangular sliding plates 904 are slidingly installed in the two rectangular sliding grooves 903, respectively, a plurality of ventilation grooves 905 are formed in the right side and the left side of the sealing box 901, respectively, the plurality of ventilation grooves 905 penetrate through the two rectangular sliding grooves 903, respectively, a limiting rectangular plate one 906 is fixedly installed on the side away from each other of the two rectangular sliding plates 904, respectively, one end away from each other of the two limiting rectangular plates one 906 extends out of the two rectangular sliding grooves 903, respectively, a limiting rectangular plate two 907 is fixedly installed on the left side and the right side of the sealing box 901, respectively, two closing springs 908 are fixedly installed on the top of the two limiting rectangular plate two 907, respectively, and the top ends of the two closing springs 908 are fixedly connected with the two limiting rectangular plate one 906, respectively.

[0050] T-shaped slide plate 806 will contact the limiting rectangular plate 1 906 and push the limiting rectangular plate 1 906 to descend during the descending process, the limiting rectangular plate 1 906 will drive the rectangular slide plate 904 to descend, at this time the closing spring 908 will be compressed and deformed, at this time the descending of the rectangular slide plate 904 will open a plurality of ventilation slots 905, at this time the poison 902 will produce volatilization and emit toxic gas to carry out experiments, and after the experiment is finished, make the T-shaped slide plate 806 away from the limiting rectangular plate 1 906, under the elastic force of the closing spring 908, the sealed box 901 can be sealed again to prevent the leakage of toxic gas, thereby improving the flexibility of the device.

[0051] As shown in Figure 1 - Figure 8 A method for a micro-environment detection device for biological toxicology research, the method steps are as follows:

[0052] S1: Ensure the air pressure in the device;

[0053] S2: Oxygen supply to ensure the survival of the organism;

[0054] S3: Flexible sealing of toxic gas;

[0055] S4: Prevent dust from neutralizing the solution.

[0056] In the process of double threaded rod 2 rotation will drive several drive plate 4 rotation, drive plate 4 in the process of rotation will contact L-shaped transmission plate 501, L-shaped transmission plate 501 will be under the action of its inclined surface to the direction of detection box 1 close to the movement, at this time the release spring 503 compression deformation, L-shaped transmission plate 501 will drive the push plate 506 movement, push plate 506 drive release plate 507 movement, release plate 507 after passing through the air slot 505 detection box 1 in the mixed gas will enter the release tank 504, after the drive plate 4 away from L-shaped transmission plate 501, release plate 507 will be under the action of release spring 503 elastic force to push release tank 504 mixed gas from the gas pipe 509 into the neutralization tank 508 in the neutralization solution, so as to maintain stable air pressure to avoid the continuous input of air resulting in detection box 1 in the air pressure rise, influence the accuracy of the experiment; the sealing box 901 is placed into the detection box 1 in the designated slot, close the sealing plate 609, sealing plate 609 in contact with two trapezoidal plate 608 will move away from the sealing plate 609 direction, at this time the limit spring 607 compression deformation, after the sealing plate 609 close to complete, trapezoidal plate 608 will be under the action of limit spring 607 drive trapezoidal plate 608 reset, at this time the back of trapezoidal plate 608 will be close to the front of sealing plate 609 guarantee the sealing property of detection box 1, avoid the toxic gas in the detection box 1 from the detection box 1 leakage influence to the health of the staff, then start the drive motor 3, drive motor 3 drive double threaded rod 2 rotation, double threaded rod 2 drive several fan blade 703 rotation, fan blade 703 will produce suction, suction will be through the air inlet L-shaped pipe 705 and hemispherical filter plate 701 will be outside the air into the detection box 1, so as to ensure the normal supply of oxygen in detection box 1, avoid long time experiment resulting in detection box 1 in the biological death due to lack of oxygen influence experiment effect, hemispherical filter plate 701 can effectively avoid the dust impurities into the detection box 1;

[0057] The double thread rod 2 drives the two inner threaded blocks 804 to approach each other in rotation, the inner threaded blocks 804 drive the connecting plate 807 to move, the connecting plate 807 drives the T-shaped slide plate 806 to descend, the T-shaped slide plate 806 contacts the limiting rectangular plate one 906 and drives the limiting rectangular plate one 906 to descend in the process of descending, the limiting rectangular plate one 906 drives the rectangular slide plate 904 to descend, at this time, the closing spring 908 will be compressed and deformed, at this time, the rectangular slide plate 904 descending will open a plurality of ventilation slots 905, at this time, the poison 902 will volatilize and emit toxic gas to carry out experiments, and the T-shaped slide plate 806 leaves the limiting rectangular plate one 906 at the end of the experiment, and the sealing box 901 can be sealed again under the elastic force of the closing spring 908, so as to prevent the leakage of toxic gas and improve the flexibility of the device; the mixed gas input into the neutralization tank 508 contains toxic gas, if the toxic gas is alkaline, the neutralizing solution is acidic, if the toxic gas is acidic, the neutralizing solution is alkaline, and after the reaction of the toxic gas and the solution, water and some harmless gas are generated, as the gas in the neutralization tank 508 becomes more and more, the gas will enter the grooved cylinder 601 through the hole on the grooved cylinder 601, the gas will drive the T-shaped hollow circular plate 602 to move away from the detection tank 1, at this time, the sealing spring 603 is stretched and deformed, when the air outlet hole 604 on the T-shaped hollow circular plate 602 leaves the grooved cylinder 601, the gas will be discharged from the sealing spring 603, when the gas pressure in the neutralization tank 508 is low, the sealing property of the grooved cylinder 601 can be ensured under the elastic force of the sealing spring 603, so as to avoid the dust and gas outside from entering the neutralization tank 508 and affecting the reaction of the neutralizing solution and the toxic gas, and the temperature sensor can detect the body temperature change of the organism during a long time of experiment, which has important significance for studying the influence of the poison on the metabolism of the organism, because the change of the metabolism rate often leads to the fluctuation of the body temperature, the heart rate sensor can measure the heart rate of the animal, so as to understand whether the poison affects the function of the cardiovascular system, and the respiration sensor can monitor the respiration frequency and depth of the organism, so as to reflect the effect of the poison on the respiratory system.

[0058] The preferred embodiments of the application disclosed above are only used to help explain the application. The preferred embodiments do not describe all the details and limit the application to the specific embodiments described. Obviously, many modifications and changes can be made according to the content of the specification. The specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the application, so that those skilled in the art can well understand and utilize the application. The application is limited by the claims and their entire scope and equivalents.

Claims

1. A microenvironment detection device for biotoxicology research, comprising a detection box (1), a double-threaded rod (2) rotatably mounted in the detection box (1), the double-threaded rod (2) passing through the detection box (1), a drive motor (3) fixedly mounted on the right side of the detection box (1), an output shaft of the drive motor (3) fixedly connected to the right end of the double-threaded rod (2), and a plurality of drive plates (4) fixedly mounted on the outer wall of the double-threaded rod (2), characterized in that: Also includes: A pressure release mechanism (5) is provided, wherein the pressure release mechanism (5) comprises an L-shaped transmission plate (501) slidably mounted on the left inner wall of the detection box (1), the right end of the L-shaped transmission plate (501) extends into the detection box (1), a fixed plate (502) is fixedly sleeved on the L-shaped transmission plate (501), a pressure release spring (503) is sleeved on the L-shaped transmission plate (501), the left end of the pressure release spring (503) is fixedly connected to the fixed plate (502), the right end of the pressure release spring (503) is fixedly connected to the detection box (1), a pressure release box (504) is fixedly mounted on the left inner wall of the detection box (1), and the pressure release box (504) is fixedly mounted on the left inner wall of the detection box (1). ) are respectively provided with air inlet grooves (505), a push plate (506) is fixedly installed on the left side of the L-shaped transmission plate (501), the left end of the push plate (506) extends into the pressure relief box (504) and is slidably connected to the pressure relief box (504), a pressure relief plate (507) is fixedly installed on the left end of the push plate (506), and the pressure relief plate (507) is slidably connected to the pressure relief box (504), a neutralization box (508) is fixedly installed on the left side of the detection box (1), and an air supply pipe (509) is fixedly installed on the right inner wall of the neutralization box (508), and the air supply pipe (509) is communicated with the pressure relief box (504).

2. A microenvironment detection device for biotoxicology research according to claim 1, characterized in that: The neutralization box (508) is provided with a sealing mechanism (6), which comprises a grooved cylinder (601) fixedly mounted on the left side of the neutralization box (508), the right end of the grooved cylinder (601) extending into the neutralization box (508), a T-shaped hollow circular plate (602) slidingly mounted in the grooved cylinder (601), the left end of the T-shaped hollow circular plate (602) extending out of the grooved cylinder (601), a sealing spring (603) fixedly mounted on the right side of the T-shaped hollow circular plate (602), the right end of the sealing spring (603) fixedly connected to the right inner wall of the grooved cylinder (601), and a plurality of air outlet holes (604) are provided on the outer wall of the T-shaped hollow circular plate (602).

3. The microenvironment detection device for biotoxicology research according to claim 2, characterized in that: Two strip plates (605) are fixedly mounted on the front of the detection box (1), and T-shaped moment rods (606) are slidably mounted on the two strip plates (605). The two T-shaped moment rods (606) respectively penetrate the two strip plates (605), and the two T-shaped moment rods (606) are respectively sleeved with limit springs (607). The ends of the two limit springs (607) that are away from each other are respectively fixedly connected to the two T-shaped moment rods (606), and the ends of the two limit springs (607) that are close to each other are respectively fixedly connected to the two strip plates (605). The ends of the two T-shaped moment rods (606) that are away from each other are respectively fixedly mounted with trapezoidal plates (608). A sealing plate (609) is slidably mounted on the front of the detection box (1), and the sealing plate (609) contacts the back surfaces of the two trapezoidal plates (608).

4. The microenvironment detection device for biotoxicology research according to claim 3, characterized in that: A ventilation mechanism (7) is provided at the top of the detection box (1). The ventilation mechanism (7) includes a hemispherical filter plate (701) fixedly installed on the top of the detection box (1). An air box (702) is fixedly installed on the inner wall of the top of the detection box (1). The double threaded rod (2) penetrates through the air box (702) and is rotatably connected to the air box (702). A plurality of fan blades (703) are fixedly installed on the outer wall of the double threaded rod (2). A plurality of air outlet round holes (704) are formed on the left side of the air box (702). An intake L-shaped pipe (705) is fixedly installed on the right side of the air box (702). The top end of the intake L-shaped pipe (705) communicates with the hemispherical filter plate (701).

5. The microenvironment detection device for biotoxicology research according to claim 4, characterized in that: Two moving mechanisms (8) are provided in the detection box (1). The moving mechanism (8) includes a slide bar (800) fixedly installed on the inner wall of the left side of the detection box (1). The right end of the slide bar (800) is fixedly connected to the air box (702). A circular ring block (801) is fixedly sleeved on the slide bar (800). An annular adaptor block (802) is provided in the detection box (1). A moving spring (803) is fixedly installed at the left end of the circular ring block (801). The left end of the moving spring (803) is fixedly connected to the annular adaptor block (802). An internally threaded block (804) is threadedly sleeved on the double threaded rod (2).

6. The microenvironment detection device for biotoxicology research according to claim 5, characterized in that: The slide bar (800) penetrates through the internally threaded block (804) and is slidably connected to the internally threaded block (804). A U-shaped limiting plate (805) is fixedly installed on the inner wall of the top of the detection box (1). A T-shaped sliding plate (806) is slidably installed in the U-shaped limiting plate (805). The T-shaped sliding plate (806) penetrates through the U-shaped limiting plate (805) and is slidably connected to the U-shaped limiting plate (805). The bottom end of the internally threaded block (804) is hingedly installed with a connecting plate (807). The bottom end of the connecting plate (807) is hingedly connected to the T-shaped sliding plate (806).

7. The microenvironment detection device for biotoxicology research according to claim 6, characterized in that: The detection box (1) is provided with a closing mechanism (9), the closing mechanism (9) comprising a sealing box (901) provided in a bottom groove of the detection box (1), a poison (902) provided in the sealing box (901), two rectangular chutes (903) provided in the sealing box (901), rectangular slides (904) slidably installed in the two rectangular chutes (903), a plurality of ventilation slots (905) provided on the right and left sides of the sealing box (901), the plurality of ventilation slots (905) all passing through the two rectangular chutes (903). 03), a limiting rectangular plate 1 (906) is fixedly installed on the side away from each other of the two rectangular slides (904), and the ends of the two limiting rectangular plates 1 (906) away from each other extend to the outside of the two rectangular slides (903), and a limiting rectangular plate 2 (907) is fixedly installed on the left and right sides of the sealing box (901), and two closing springs (908) are fixedly installed on the tops of the two limiting rectangular plates 2 (907), and the tops of the two closing springs (908) are fixedly connected to the two limiting rectangular plates 1 (906).

8. A method for using a microenvironment detection device for biotoxicology research, using the microenvironment detection device for biotoxicology research according to claim 7, characterized in that: The steps are as follows: S1: Ensure the air pressure inside the device; S2: Oxygen supply ensures biological survival; S3: Flexible sealed gas; S4: Protect the neutralizing solution from dust.

Citation Information

Patent Citations

  • Automatic cell culture plate production line and production process thereof

    CN118385240A

  • Hydrops drainage device and drainage method for cardiovascular medicine department

    CN118576795A