Umbilical cord essence extract anti-aging nourishing mask and preparation method thereof

By separately packaging the freeze-dried umbilical cord extract and the mask stock solution independently, the problem that the umbilical cord extract is difficult to preserve the biological activity in the mask for a long time is solved, and the effective anti-aging effect and long-term use of the mask are achieved.

CN119587441APending Publication Date: 2025-03-11GUANGXI PERFECT MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202411738213.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-29
Publication Date
2025-03-11

AI Technical Summary

Technical Problem

Due to the influence of moisture and oxygen in existing facial masks, bioactive ingredients are difficult to preserve for a long time, affecting the effectiveness of the product.

Method used

By separately packaging the umbilical cord extract lyophilized powder and mask stock solution, avoiding the influence of moisture and oxygen, ensuring that the biological activity of the umbilical cord extract is maintained.

Benefits of technology

It effectively extends the biological activity retention time of umbilical cord extract, improves the anti-aging effect of the mask, and ensures the long-term use effect of the product.

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Abstract

The invention discloses an umbilical cord essence extract anti-aging nourishing mask and a preparation method thereof.The umbilical cord essence extract anti-aging nourishing mask comprises umbilical cord extract freeze-dried powder, and the umbilical cord extract freeze-dried powder is arranged in a first bottle body; the umbilical cord extract freeze-dried powder is prepared from the following raw materials: (animal) umbilical cord extract, mannitol, oligopeptide-1, oligopeptide-3, oligopeptide-5, glutathione, serum albumin, trehalose, glycine, disodium hydrogen phosphate, polysorbate-20, sodium dihydrogen phosphate and deionized water. The mask raw liquid is arranged in the second bottle body, and the mask raw liquid is prepared from the following raw materials: 1, 2-hexanediol, hydrolyzed sodium hyaluronate, a centella asiatica leaf extract, palmitoyl tripeptide-1, tripeptide-1, acetyl hexapeptide-8, tripeptide-1 copper, carnosine, sodium hyaluronate, ethylhexylglycerin, glycerin, propylene glycol, phenoxyethanol, xanthan gum and deionized water. According to the invention, the umbilical cord extract and the mask stock solution are separately and independently packaged, so that the use effect of the product is ensured.
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Description

Technical Field

[0001] The invention relates to the technical field of skin care products, and in particular to an anti-aging nourishing facial mask with umbilical cord essence extract and a preparation method thereof. Background Art

[0002] Umbilical cord essence extract is a special secretion component extracted from animal umbilical cords. It contains a large number of biologically active ingredients such as cytokines, active peptides, enzymes and amino acids. It is widely used in skin care products, medical treatment, cosmetic surgery and other fields.

[0003] When umbilical cord essence extract is used in the field of skin care products, the growth factors and collagen in the umbilical cord essence extract can stimulate the regeneration and repair of skin cells, thereby reducing fine lines and wrinkles and increasing skin elasticity and firmness. It is currently widely used in creams, lotions, water solutions, patches, facial masks, dressings and other skin care products.

[0004] When the umbilical cord essence extract is used in a facial mask, the existing technology usually involves directly mixing the umbilical cord essence extract with the facial mask material and finally using it as a product. However, in fact, the moisture and oxygen in the material will have a great impact on the bioactive ingredients in the umbilical cord essence extract, and low-temperature storage is usually required. The bioactive ingredients in the umbilical cord essence extract are likely to be completely inactivated within 10-20 days at room temperature, affecting the use effect of the product. Summary of the invention

[0005] The purpose of the present invention is to provide an umbilical cord essence extract anti-aging nourishing facial mask and a preparation method thereof, so as to solve the problems mentioned in the above background technology.

[0006] In order to solve the above technical problems, the present invention provides an umbilical cord essence extract anti-aging nourishing facial mask and a preparation method thereof, which comprises:

[0007] Umbilical cord extract freeze-dried powder, the umbilical cord extract freeze-dried powder is arranged in a first bottle, and the umbilical cord extract freeze-dried powder is made of the following raw materials: (animal) umbilical cord extract, mannitol, oligopeptide-1, oligopeptide-3, oligopeptide-5, glutathione, serum albumin, trehalose, glycine, disodium hydrogen phosphate, polysorbate-20, sodium dihydrogen phosphate and deionized water.

[0008] A facial mask stock solution, which is arranged in the second bottle body, and is made of the following raw materials: 1,2-hexanediol, hydrolyzed sodium hyaluronate, Centella asiatica leaf extract, palmitoyl tripeptide-1, tripeptide-1, acetyl hexapeptide-8, tripeptide-1 copper, carnosine, sodium hyaluronate, ethylhexylglycerin, glycerin, propylene glycol, phenoxyethanol, xanthan gum and deionized water.

[0009] Furthermore, the umbilical cord extract freeze-dried powder is made of the following raw materials in percentage by mass: (animal) umbilical cord extract 24%, mannitol 5%, oligopeptide-10.3%, oligopeptide-30.5%, oligopeptide-50.3%, glutathione 2%, serum albumin 1%, trehalose 0.7%, glycine 0.8%, disodium hydrogen phosphate 0.4%, polysorbate-20 0.1%, sodium dihydrogen phosphate 0.06% and the remainder deionized water.

[0010] Furthermore, the facial mask stock solution is made of the following raw materials in percentage by mass: 0.5% 1,2-hexanediol, 0.1% hydrolyzed sodium hyaluronate, 0.5% Centella asiatica leaf extract, 0.2% palmitoyl tripeptide-1, 0.5% tripeptide-1, 0.1% acetyl hexapeptide-8, 0.1% tripeptide-1 copper, 0.3% carnosine, 0.4% sodium hyaluronate, 0.25% ethylhexylglycerin, 3% glycerol, 3.2% propylene glycol, 0.35% phenoxyethanol, 0.5% xanthan gum and the remainder deionized water.

[0011] Further, the following steps are included:

[0012] S1. Weigh the raw materials for preparing umbilical cord extract freeze-dried powder and facial mask stock solution respectively according to mass percentage;

[0013] S2, (animal) umbilical cord extract, mannitol, oligopeptide-1, oligopeptide-3, oligopeptide-5, glutathione, trehalose, arginine and deionized water are mixed and stirred to obtain a mixed solution, after cooling to room temperature, disodium hydrogen phosphate and sodium dihydrogen phosphate are added to adjust the pH value of the mixed solution to 5.5-7, and then polysorbate-20 is added and mixed uniformly to obtain a lyophilized powder mixed solution;

[0014] S3, 1,2-hexanediol, hydrolyzed sodium hyaluronate, Centella asiatica leaf extract, palmitoyl tripeptide-1, tripeptide-1, acetyl hexapeptide-8, tripeptide-1 copper, carnosine, sodium hyaluronate, ethylhexylglycerin, glycerin, propylene glycol, phenoxyethanol, xanthan gum and deionized water are mixed and stirred until uniform, and then cooled to room temperature to obtain a mask stock solution mixture;

[0015] S4, filtering the freeze-dried powder mixture and the mask stock solution mixture through filters to obtain a freeze-dried powder filtrate and a mask stock solution respectively;

[0016] S5, pre-freezing the freeze-dried powder filtrate at -20°C for 8-12 hours, and then freeze-drying to obtain freeze-dried powder;

[0017] S6. Fill the freeze-dried powder into the first bottle and the mask concentrate into the second bottle.

[0018] Furthermore, in step S2, the insulation temperature is 60° C., and after adding polysorbate 20, the mixture is stirred for 20 minutes to be evenly mixed.

[0019] Furthermore, in step S3, 1,2-hexanediol, glycerol, and propylene glycol are first added to deionized water in sequence, kept warm at 35°C, and stirred until uniform, then hydrolyzed sodium hyaluronate and sodium hyaluronate are added, kept warm at 35°C, and stirred until uniform, and Centella asiatica leaf extract, palmitoyl tripeptide-1, tripeptide-1, acetyl hexapeptide-8, tripeptide-1 copper, and carnosine are added in sequence while stirring, and finally ethylhexylglycerin, phenoxyethanol, and xanthan gum are added and stirred until uniform.

[0020] Furthermore, in step S4, the freeze-dried powder mixture and the mask stock solution mixture are filtered through a first filter and a second filter respectively in sequence, the pore size of the first filter is 0.45 μm, and the pore size of the second filter is 0.22 μm.

[0021] Furthermore, the freeze-drying process in step S5 includes:

[0022] Primary sublimation: make the vacuum degree reach 15Pa, raise the temperature to -3℃, and maintain for 12h;

[0023] Secondary sublimation: bring the temperature to 35°C within 2 hours and keep it warm for 8 hours.

[0024] The beneficial effects of the present invention are as follows: the present invention uses umbilical cord tissue extract, multiple oligopeptides, multiple polypeptides and multiple repairing ingredients to synergistically enhance the effect, so that the mask has an anti-aging effect. At the same time, the umbilical cord extract and the mask stock solution are separately packaged, so that when the product is not in use, the moisture and oxygen in the material body can be prevented from affecting the biological activity of the umbilical cord extract, solving the problem that the activity of the umbilical cord extract in the liquid formula is difficult to preserve for a long time, and ensuring the use effect of the product. DETAILED DESCRIPTION

[0025] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiment is only one embodiment of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0026] In order to make the purpose, technical solutions and advantages of the present application clearer, the present application is further described in detail below in conjunction with specific embodiments.

[0027] In the following description, references to "one embodiment", "an embodiment", "an example", "an example", etc. indicate that the embodiment or example described in this way may include specific features, structures, characteristics, properties, elements or limitations, but not every embodiment or example necessarily includes the specific features, structures, characteristics, properties, elements or limitations. In addition, repeated use of the phrase "according to one embodiment of the present application" may refer to the same embodiment, but does not necessarily refer to the same embodiment.

[0028] In the present invention, the experimental methods used are conventional methods unless otherwise specified, and the materials, reagents, etc. used are all commercially available unless otherwise specified.

[0029] The present invention discloses an anti-aging nourishing facial mask containing umbilical cord essence extract, which comprises:

[0030] Umbilical cord extract freeze-dried powder, the umbilical cord extract freeze-dried powder is set in the first bottle, and the umbilical cord extract freeze-dried powder is made of the following raw materials: (animal) umbilical cord extract, rich in various growth factors, amino acids and nutrients, which helps to promote the regeneration and repair of skin cells, thereby slowing down the aging process.

[0031] Mannitol is a polyol with moisturizing and stabilizing effects. It helps the skin retain moisture while enhancing the stability of the product.

[0032] Oligopeptide-1, oligopeptide-3 and oligopeptide-5, these oligopeptide ingredients have the functions of promoting cell regeneration, repairing damaged skin and enhancing skin barrier function.

[0033] Glutathione, an antioxidant, protects cells from damage caused by oxidative stress and contributes to anti-aging and whitening.

[0034] Serum albumin can provide the skin with the necessary nutrition and energy, while promoting the metabolism and renewal of skin cells.

[0035] Trehalose, a natural sugar extracted from seaweed, has excellent moisturizing effects. Glycine, has the effect of moisturizing and nourishing the skin.

[0036] Disodium hydrogen phosphate and sodium dihydrogen phosphate act as buffers to adjust the pH of the product.

[0037] Polysorbate-20, a surfactant, has emulsifying, dispersing and stabilizing effects. It can help other ingredients disperse better in the solution and improve the stability and absorbability of the product.

[0038] Deionized water, purified water that has been treated to remove ionic impurities, is the base solvent for this product.

[0039] The mask stock solution is arranged in the second bottle body, and the mask stock solution is made of the following raw materials: 1,2-hexanediol, which is a moisturizing agent and has good hygroscopicity and water retention.

[0040] Hydrolyzed sodium hyaluronate, a highly effective moisturizing ingredient, helps other skin care products to be better absorbed. Centella asiatica leaf extract has anti-inflammatory, soothing and anti-allergic effects, and can effectively reduce the production of pro-inflammatory mediators.

[0041] Palmitoyl Tripeptide-1 increases skin permeability, helps restore the skin's natural texture, and also has anti-inflammatory properties.

[0042] Tripeptide-1, has antioxidant effect.

[0043] Acetyl Hexapeptide-8 has anti-wrinkle effects and can reduce the contraction of facial muscles.

[0044] Copper Tripeptide-1 promotes skin repair and regeneration and often works synergistically with other peptide ingredients to enhance anti-aging effects.

[0045] Carnosine, an antioxidant, protects cells from oxidative stress. Sodium hyaluronate, highly effective moisturizer.

[0046] Ethylhexylglycerin, which has antibacterial and moisturizing properties, can enhance the stability of the product. Glycerin, a common humectant, can attract and retain moisture in the skin.

[0047] Propylene glycol, which has moisturizing and antibacterial properties.

[0048] Phenoxyethanol, a preservative, is used to ensure the sterility of the product.

[0049] Xanthan gum, as a thickener, adjusts the viscosity of the mask solution, making it easier to use and apply.

[0050] Deionized water, purified water that has been treated to remove ionic impurities, is the base solvent for this product.

[0051] When using, take out one bottle of umbilical cord extract freeze-dried powder and one bottle of mask stock solution, open the bottle cap, pour the mask stock solution into the umbilical cord extract freeze-dried powder, cover the bottle cap, shake the mixture to mix it evenly to obtain the freeze-dried stock solution, and then use it. Users can directly use it as a smearable mask, that is, take an appropriate amount of freeze-dried stock solution and evenly apply it to the skin, and massage until it is fully absorbed. In addition, it can also be used as a patch mask with a disposable film cloth, that is, put the disposable film cloth into the freeze-dried stock solution bottle, cover the bottle cap again, shake it evenly, let it stand for 5 minutes, take out the disposable film cloth, gently apply it on the face, and remove it after 15-20 minutes.

[0052] The present invention uses umbilical cord tissue extract, multiple oligopeptides, multiple polypeptides and multiple repairing ingredients to synergistically enhance the effect, so that the mask has an anti-aging effect. At the same time, the umbilical cord extract and the mask stock solution are separately packaged independently, so that when the product is not in use, the moisture and oxygen in the material body can be prevented from affecting the biological activity of the umbilical cord extract, solving the problem that the activity of the umbilical cord extract in the liquid formula is difficult to preserve for a long time, and ensuring the use effect of the product.

[0053] In one embodiment, the umbilical cord extract freeze-dried powder is made of the following raw materials in percentage by mass: (animal) umbilical cord extract 24%, mannitol 5%, oligopeptide-10.3%, oligopeptide-30.5%, oligopeptide-50.3%, glutathione 2%, serum albumin 1%, trehalose 0.7%, glycine 0.8%, disodium hydrogen phosphate 0.4%, polysorbate-20 0.1%, sodium dihydrogen phosphate 0.06% and the balance deionized water.

[0054] In one embodiment, the facial mask stock solution is made of the following raw materials in percentage by mass: 0.5% 1,2-hexanediol, 0.1% hydrolyzed sodium hyaluronate, 0.5% Centella asiatica leaf extract, 0.2% palmitoyl tripeptide-1, 0.5% tripeptide-1, 0.1% acetyl hexapeptide-8, 0.1% tripeptide-1 copper, 0.3% carnosine, 0.4% sodium hyaluronate, 0.25% ethylhexylglycerin, 3% glycerol, 3.2% propylene glycol, 0.35% phenoxyethanol, 0.5% xanthan gum, and the balance deionized water.

[0055] The preparation method of the umbilical cord essence extract anti-aging nourishing facial mask comprises the following steps:

[0056] S1. Weigh the raw materials for preparing umbilical cord extract freeze-dried powder and facial mask stock solution respectively according to mass percentage;

[0057] S2, (animal) umbilical cord extract, mannitol, oligopeptide-1, oligopeptide-3, oligopeptide-5, glutathione, trehalose, arginine and deionized water are mixed and stirred to obtain a mixed solution, after cooling to room temperature, disodium hydrogen phosphate and sodium dihydrogen phosphate are added to adjust the pH value of the mixed solution to 5.5-7, and then polysorbate-20 is added and mixed uniformly to obtain a lyophilized powder mixed solution;

[0058] S3, 1,2-hexanediol, hydrolyzed sodium hyaluronate, Centella asiatica leaf extract, palmitoyl tripeptide-1, tripeptide-1, acetyl hexapeptide-8, tripeptide-1 copper, carnosine, sodium hyaluronate, ethylhexylglycerin, glycerin, propylene glycol, phenoxyethanol, xanthan gum and deionized water are mixed and stirred until uniform, and then cooled to room temperature to obtain a mask stock solution mixture;

[0059] S4, filtering the freeze-dried powder mixture and the mask stock solution mixture through filters to obtain a freeze-dried powder filtrate and a mask stock solution respectively;

[0060] S5, pre-freezing the freeze-dried powder filtrate at -20°C for 8-12 hours, and then freeze-drying to obtain freeze-dried powder;

[0061] S6. Fill the freeze-dried powder into the first bottle and the mask concentrate into the second bottle.

[0062] In one embodiment, the temperature in step S2 is 60° C. After adding polysorbate 20, the mixture is stirred for 20 minutes to be uniformly mixed. In this embodiment, a vacuum mixer is used.

[0063] First, pre-mix (animal) umbilical cord extract, mannitol, oligopeptide-1, oligopeptide-3, oligopeptide-5, glutathione, trehalose, arginine and deionized water, and preheat the vacuum mixer. Pour the pre-mixed solution into the container of the vacuum mixer. Start the vacuum mixer, adjust the stirring speed and the position of the shear head for efficient mixing, and turn on the vacuum pump to remove bubbles and dissolved gases in the solution. After the mixture is cooled to room temperature, add disodium hydrogen phosphate and sodium dihydrogen phosphate to adjust the pH value of the mixture to 5.5-7, and then add polysorbate-20 and stir for 20 minutes to mix evenly.

[0064] In one embodiment, in step S3, 1,2-hexanediol, glycerol, and propylene glycol are first added to deionized water in sequence, kept warm at 35°C, and stirred until uniform. Then, hydrolyzed sodium hyaluronate and sodium hyaluronate are added, kept warm at 35°C, and stirred until uniform. Centella asiatica leaf extract, palmitoyl tripeptide-1, tripeptide-1, acetyl hexapeptide-8, tripeptide-1 copper, and carnosine are added in sequence while stirring. Finally, ethylhexylglycerin, phenoxyethanol, and xanthan gum are added and stirred until uniform.

[0065] In one embodiment, the freeze-dried powder mixture and the mask stock solution mixture in step S4 are filtered through a first filter and a second filter respectively, and the pore size of the first filter is 0.45 μm for coarse filtration to remove larger particles, impurities and aggregates to ensure the initial purity of the solution. The pore size of the second filter is 0.22 μm for fine filtration to further remove tiny particles, bacteria and other microorganisms to ensure the sterility of the solution, and the finished mask stock solution is filled into a vial.

[0066] In one embodiment, the freeze-drying process in step S5 comprises:

[0067] Primary sublimation: make the vacuum degree reach 15Pa, raise the temperature to -3℃, and maintain for 12h; adjust the vacuum degree of the freeze dryer to 15Pa to create an environment conducive to water sublimation and reduce the pressure barrier during the sublimation process. Then, adjust the temperature to -3℃.

[0068] Since this temperature is lower than the freezing point of the water in the material, but high enough for the water to start to change directly from solid to gas (i.e. sublimate), keep it at -3℃ for 12 hours to ensure that most of the water in the material can be removed by sublimation.

[0069] Secondary sublimation: The temperature reaches 35°C within 2 hours and is kept warm for 8 hours. This temperature increase process needs to be carried out slowly to avoid damage to the structure of the material. When the temperature reaches 35°C, maintain this temperature for 8 hours. This insulation stage is to further remove the residual moisture in the material and ensure the dryness and stability of the freeze-dried product.

[0070] After the secondary sublimation is completed, the temperature is gradually lowered to room temperature or slightly lower so that the freeze-dried product can be taken out of the freeze dryer and filled into vials.

[0071] Protein determination in facial mask: This facial mask was determined according to the BCA method (Appendix VIIM Method 4 of Part II of the Pharmacopoeia of the People's Republic of China 2010 edition).

[0072] Experimental group 1: Mix the newly prepared umbilical cord extract freeze-dried powder with the mask stock solution.

[0073] Experimental group 2: After production, the umbilical cord extract freeze-dried powder and the mask concentrate were filled into vials respectively and sealed for 10 days.

[0074] Experimental Group 3: After production, the umbilical cord extract freeze-dried powder and the mask stock solution were mixed and then sealed and placed for 10 days.

[0075] The experimental results are as follows:

[0076] Table 1:

[0077] Experimental group number Protein concentration (mg / ml) 1 3.21 2 3.17 3 2.46

[0078] As can be seen from Table 1, the protein concentrations of experimental groups 1 and 2 are not much different, but the protein concentration of experimental group 3 is significantly reduced, that is, the protein is inactivated to a greater extent. Therefore, the umbilical cord extract and the mask concentrate are packaged separately to prevent the moisture and oxygen in the material from affecting the biological activity of the umbilical cord extract when the product is not in use.

[0079] Skin changes before and after 30 days of use:

[0080] Experimental group 1: 25-year-old female, normal face washing and non-functional moisturizing water wiped the whole face, sun protection during the day, and then tested for 30 consecutive days as the pre-use data. After that, normal face washing and non-functional moisturizing water wiped the whole face, sun protection during the day, and the mask was applied continuously for 30 days as the post-use data.

[0081] Experimental group 2: 30-year-old female, normal face washing and non-functional moisturizing water wiped the whole face, sun protection during the day, and then tested for 30 consecutive days as the pre-use data. After that, normal face washing and non-functional moisturizing water wiped the whole face, sun protection during the day, and the mask was used for 30 consecutive days as the post-use data.

[0082] Experimental group 3: 35-year-old female, normal face washing and non-functional moisturizing water wiped the whole face, sun protection during the day, and the test was conducted after 30 consecutive days as the pre-use data. After that, normal face washing and non-functional moisturizing water wiped the whole face, sun protection during the day, and the test was conducted after 30 consecutive days as the post-use data.

[0083] The VISSIA skin detector is used to test the eye skin (for the inner eye socket area) to obtain an absolute score. The absolute score reflects the size, area and density of wrinkles and is most useful in evaluating the progress of treatment over time, that is, the lower the absolute score, the better.

[0084] The experimental results are shown in Table 2:

[0085]

[0086] It can be seen from Table 2 that the absolute scores of experimental groups 1-3 have all decreased to varying degrees, that is, the severity of wrinkles has all decreased, and this product has anti-wrinkle and anti-aging effects.

[0087] The present invention uses umbilical cord tissue extract, multiple oligopeptides, multiple polypeptides and multiple repairing ingredients to synergistically enhance the effect, so that the mask has an anti-aging effect. At the same time, the umbilical cord extract and the mask stock solution are separately packaged independently, so that when the product is not in use, the moisture and oxygen in the material body can be prevented from affecting the biological activity of the umbilical cord extract, solving the problem that the activity of the umbilical cord extract in the liquid formula is difficult to preserve for a long time, and ensuring the use effect of the product.

[0088] The above description of the disclosed embodiments enables one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. An umbilical cord essence extract anti-aging nourishing facial mask, characterized in that: include: Umbilical cord extract freeze-dried powder, the umbilical cord extract freeze-dried powder is arranged in a first bottle, and the umbilical cord extract freeze-dried powder is made of the following raw materials: (animal) umbilical cord extract, mannitol, oligopeptide-1, oligopeptide-3, oligopeptide-5, glutathione, serum albumin, trehalose, glycine, disodium hydrogen phosphate, polysorbate-20, sodium dihydrogen phosphate and deionized water. A facial mask stock solution, which is arranged in the second bottle body, and is made of the following raw materials: 1,2-hexanediol, hydrolyzed sodium hyaluronate, Centella asiatica leaf extract, palmitoyl tripeptide-1, tripeptide-1, acetyl hexapeptide-8, tripeptide-1 copper, carnosine, sodium hyaluronate, ethylhexylglycerin, glycerin, propylene glycol, phenoxyethanol, xanthan gum and deionized water.

2. The anti-aging nourishing facial mask of umbilical cord essence extract according to claim 1, characterized in that: The umbilical cord extract freeze-dried powder is prepared from the following raw materials in percentage by mass: 24% of (animal) umbilical cord extract, 5% of mannitol, 0.3% of oligopeptide-1, 0.5% of oligopeptide-3, 0.3% of oligopeptide-5, 2% of glutathione, 1% of serum albumin, 0.7% of trehalose, 0.8% of glycine, 0.4% of disodium hydrogen phosphate, 0.1% of polysorbate-20, 0.06% of sodium dihydrogen phosphate and the balance of deionized water.

3. The anti-aging nourishing facial mask of umbilical cord essence extract according to claim 1, characterized in that: The mask stock solution is made of the following raw materials in percentage by mass: 0.5% of 1,2-hexanediol, 0.1% of hydrolyzed sodium hyaluronate, 0.5% of Centella asiatica leaf extract, 0.2% of palmitoyl tripeptide-1, 0.5% of tripeptide-1, 0.1% of acetyl hexapeptide-8, 0.1% of tripeptide-1 copper, 0.3% of carnosine, 0.4% of sodium hyaluronate, 0.25% of ethylhexylglycerin, 3% of glycerol, 3.2% of propylene glycol, 0.35% of phenoxyethanol, 0.5% of xanthan gum and the balance of deionized water.

4. A method for preparing an anti-aging nourishing facial mask of umbilical cord essence extract according to any one of claims 1 to 3, characterized in that: The following steps are involved: S1. Weigh the raw materials for preparing umbilical cord extract freeze-dried powder and facial mask stock solution respectively according to mass percentage; S2, (animal) umbilical cord extract, mannitol, oligopeptide-1, oligopeptide-3, oligopeptide-5, glutathione, trehalose, arginine and deionized water are mixed and stirred to obtain a mixed solution, after cooling to room temperature, disodium hydrogen phosphate and sodium dihydrogen phosphate are added to adjust the pH value of the mixed solution to 5.5-7, and then polysorbate-20 is added and mixed uniformly to obtain a lyophilized powder mixed solution; S3, 1,2-hexanediol, hydrolyzed sodium hyaluronate, Centella asiatica leaf extract, palmitoyl tripeptide-1, tripeptide-1, acetyl hexapeptide-8, tripeptide-1 copper, carnosine, sodium hyaluronate, ethylhexylglycerin, glycerin, propylene glycol, phenoxyethanol, xanthan gum and deionized water are mixed and stirred until uniform, and then cooled to room temperature to obtain a mask stock solution mixture; S4, filtering the freeze-dried powder mixture and the mask stock solution mixture through filters to obtain a freeze-dried powder filtrate and a mask stock solution respectively; S5, pre-freezing the freeze-dried powder filtrate at -20°C for 8-12 hours, and then freeze-drying to obtain freeze-dried powder; S6. Fill the freeze-dried powder into the first bottle and the mask concentrate into the second bottle.

5. The method for preparing the anti-aging nourishing facial mask of umbilical cord essence extract according to claim 4, characterized in that: In the step S2, the heat preservation temperature is 60° C. After adding polysorbate 20, the mixture is stirred for 20 minutes to be evenly mixed.

6. The method for preparing the anti-aging nourishing facial mask of umbilical cord essence extract according to claim 4, characterized in that: In step S3, 1,2-hexanediol, glycerol, and propylene glycol are first added to deionized water in sequence, kept warm at 35° C., and stirred until uniform. Then, hydrolyzed sodium hyaluronate and sodium hyaluronate are added, kept warm at 35° C., and stirred until uniform. Centella asiatica leaf extract, palmitoyl tripeptide-1, tripeptide-1, acetyl hexapeptide-8, tripeptide-1 copper, and carnosine are added in sequence while stirring. Finally, ethylhexylglycerin, phenoxyethanol, and xanthan gum are added and stirred until uniform.

7. The method for preparing an anti-aging nourishing facial mask containing umbilical cord essence extract according to claim 4, characterized in that: In step S4, the freeze-dried powder mixture and the mask stock solution mixture are filtered through a first filter and a second filter respectively in sequence, the pore size of the first filter is 0.45 μm, and the pore size of the second filter is 0.22 μm.

8. The method for preparing an anti-aging nourishing facial mask containing umbilical cord essence extract according to claim 4, characterized in that: The freeze-drying process in step S5 includes: Primary sublimation: make the vacuum degree reach 15Pa, raise the temperature to -3℃, and maintain for 12h; Secondary sublimation: bring the temperature to 35°C within 2 hours and keep it warm for 8 hours.