Pharmaceutical composition for acupuncture treatment

Abstract

The invention discloses a pharmaceutical composition for acupuncture therapy. The invention belongs to the technical field of acupuncture and moxibustion. The pharmaceutical composition is prepared from the following components in parts by weight: 20 to 40 parts of moxa floss, 30 to 50 parts of herba lycopodii, 30 to 40 parts of herba speranskiae tuberculatae, 30 to 50 parts of radix salviae miltiorrhizae, 50 to 80 parts of folium artemisiae argyi, 10 to 30 parts of flos carthami, 20 to 40 parts of rhizoma corydalis and 50 to 110 parts of high-degree Baijiu. The pharmaceutical composition disclosed by the invention is combined with acupuncture treatment, so that the acupuncture treatment effect can be remarkably enhanced, and the cure rate and the remission rate of qi and blood stasis, cold-dampness blockage and pain diseases are increased; all the components in the pharmaceutical composition are natural traditional Chinese medicinal materials and are wide in source and relatively high in safety, and the preparation method is simple and easy to implement and convenient to popularize and apply; through different preparation forms, the traditional Chinese medicine composition can be flexibly applied according to different diseases and acupuncture treatment modes, and the pertinence and convenience of medicine use are improved.

Description

Technical Field

[0001] The invention belongs to the technical field of acupuncture, and specifically refers to a medicinal composition for acupuncture treatment. Background Art

[0002] Acupuncture is an ancient and effective traditional medical treatment method that is widely used and recognized around the world. Based on the theory of human meridians, it stimulates the body's own regulatory mechanism through acupuncture or moxibustion of acupoints to achieve the purpose of treating diseases, relieving symptoms and promoting recovery. Acupuncture treatment has many advantages, such as few side effects and unique therapeutic effects on certain chronic diseases and functional disorders.

[0003] However, in clinical practice, acupuncture treatment has certain limitations. On the one hand, for some diseases with more complicated conditions or longer duration, the regulatory effect of acupuncture stimulation of acupoints alone may not be enough to achieve the ideal therapeutic effect. For example, in cases of severe blood stasis, such as deep blood stasis caused by long-term traumatic injuries, poor blood circulation caused by old injuries, or severe blood stasis-type dysmenorrhea in some gynecological diseases, the mechanical stimulation of acupuncture needles alone will slow down the unblocking of meridians and blood, and the treatment cycle may be longer.

[0004] On the other hand, for arthralgia caused by cold and dampness invading the human body, especially arthralgia caused by cold and dampness, when the cold and dampness penetrate into the tendons, bones and joints, the warming power of acupuncture alone may not be able to completely dispel the cold and dampness. Similarly, in pain disorders, especially intractable pain, such as neuropathic pain, certain chronic headaches or flank pain, although acupuncture treatment can relieve pain to a certain extent, for some patients, the durability and intensity of the analgesic effect still need to be improved.

[0005] Modern medical research also shows that the efficacy of acupuncture treatment is affected by many factors, including the accurate selection of acupoints, acupuncture techniques, and individual differences in patient constitution. However, even when these factors are optimized, some patients still fail to respond to acupuncture treatment as expected. Therefore, in order to improve the efficacy of acupuncture treatment and expand its treatment range, it is of great clinical significance to develop a pharmaceutical composition that is compatible with acupuncture treatment.

[0006] Although there are some drugs or products that assist acupuncture treatment on the market, they often have problems such as single ingredients, weak targeting, and incomplete mechanism of action. For example, some drugs that only have the main function of promoting blood circulation and removing blood stasis are not effective in dealing with complex diseases with mixed cold, dampness, and blood stasis; and some external preparations that are mainly for pain relief lack the ability to comprehensively regulate the root cause of the disease. Therefore, there is an urgent need for a new drug combination that can comprehensively consider the pathological mechanisms of multiple diseases and synergize with acupuncture treatment.

[0007] In addition, with the continuous improvement of people's health needs and in-depth research on traditional medicine, the development of an efficient, safe and widely applicable acupuncture-assisted drug composition will not only help to improve the status of acupuncture treatment in the medical field, but also better meet patients' expectations for disease treatment and reduce patients' pain and medical costs. Summary of the invention

[0008] The purpose of the present invention is to provide a pharmaceutical composition for acupuncture treatment. The pharmaceutical composition of the present invention is combined with acupuncture treatment to significantly enhance the effect of acupuncture treatment, and improve the cure rate and relief rate of qi and blood stasis, cold and dampness obstruction and pain symptoms; each component in the pharmaceutical composition is a natural Chinese medicinal material with a wide range of sources and relatively high safety, and the preparation method is simple and easy, which is convenient for promotion and application; through different preparation forms, it can be flexibly applied to different symptoms and acupuncture treatment methods, thereby improving the pertinence and convenience of drug use.

[0009] In order to achieve the above-mentioned purpose, the technical scheme adopted by the present invention is as follows: a pharmaceutical composition for acupuncture treatment, comprising the following components in parts by weight: 10-60 parts of moxa, 20-70 parts of smilax glabra, 10-50 parts of radix schizonepetae, 20-60 parts of salvia miltiorrhiza, 5-50 parts of safflower, 5-45 parts of corydalis yanhusuo, and 20-200 parts of high-proof liquor.

[0010] Preferably, the pharmaceutical composition comprises the following components in parts by weight: 15-50 parts of moxa, 30-60 parts of smilax china, 20-40 parts of radix spatholobi, 30-60 parts of salvia miltiorrhiza, 10-40 parts of safflower, 10-40 parts of corydalis yanhusuo, and 30-150 parts of high-proof liquor.

[0011] Preferably, the pharmaceutical composition comprises the following components in parts by weight: 20-40 parts of moxa, 30-50 parts of lycopodiella ciliata, 30-40 parts of radix schizonepetae, 30-50 parts of salvia miltiorrhiza, 10-30 parts of safflower, 20-40 parts of corydalis yanhusuo, and 50-110 parts of high-proof liquor.

[0012] The present invention also provides a method for preparing a pharmaceutical composition for acupuncture treatment, the preparation method comprising the following steps:

[0013] (1) Preparation of extract: Mix and grind Lithospermum officinale, Rhubarb and Sanguisorba officinalis, soak and extract with strong liquor, filter and concentrate to obtain extract;

[0014] (2) Preparation of moxibustion medicine column: the drug composition is mixed and crushed, and an adhesive paste is added to prepare a moxibustion medicine column;

[0015] (3) Preparation of Corydalis yanhusuo pills: Crush the Corydalis yanhusuo and mix it with auxiliary materials, and make it into pills with refined honey.

[0016] Furthermore, in step (1), the alcohol content of the liquor is 52-60 degrees.

[0017] Furthermore, the immersion extraction time in step (1) is 24-48 hours.

[0018] Furthermore, the paste in step (2) is made from Schisandra chinensis and Galla chinensis.

[0019] Furthermore, the diameter of the drug column in step (2) is 1.5-2.0 cm.

[0020] Furthermore, the weight of the pills in step (3) is 3-5 grams.

[0021] Furthermore, the preparation method also uses the following tools: a large hand pad with a diameter of 28 cm (round), a small hand pad with a diameter of 17 cm, a 40×40 cm pure cotton white cloth (square), and a ceramic bowl with a bowl mouth diameter of 11.5 cm.

[0022] The beneficial effects achieved by the present invention using the above structure are as follows: (1) The pharmaceutical composition of the present invention combined with acupuncture treatment can significantly enhance the effect of acupuncture treatment and improve the cure rate and relief rate of qi and blood stasis, cold and dampness obstruction and pain symptoms; (2) All ingredients in the pharmaceutical composition of the present invention are natural Chinese medicinal materials with a wide range of sources and relatively high safety, and the preparation method is simple and easy to promote and apply; (3) The present invention can be flexibly applied to different symptoms and acupuncture treatment methods through different preparation forms, thereby improving the pertinence and convenience of drug use.

[0023] The present invention uses the following Chinese medicines as the effective ingredients of the acupuncture treatment composition: Among them, Danshen is the dried root and rhizome of Danshen, a plant of the Labiatae family, and its main active ingredients include tanshinone, salvianolic acid, etc. Tanshinone has antibacterial and anti-inflammatory effects, and salvianolic acid can be antioxidant and anti-platelet aggregation, and can effectively improve blood circulation, especially for diseases related to qi and blood stasis; Artemisia argyi is the dried leaves of Artemisia argyi, a plant of the Asteraceae family, and contains volatile oils such as eucalyptol and borneol. Artemisia argyi is warm in nature and has a fragrant smell. It is made into moxa wool for moxibustion. Its warm power can warm the meridians and dispel cold, dredge the meridians and relieve pain, and has significant effects in treating cold diseases such as cold-damp arthralgia and cold abdominal pain; Safflower is the dried flower of Safflower, a plant of the Asteraceae family, and its main ingredients include safflower yellow pigment and safflower glycosides. Safflower is pungent and warm in nature. It has a powerful function of promoting blood circulation and removing blood stasis. It can assist acupuncture in improving microcirculation and has a positive effect on the sequelae of stroke, limb numbness and other symptoms of poor blood circulation. Corydalis is the dried tuber of Corydalis of the poppy family, which contains a variety of alkaloids, such as corydalis butyl. Corydalis is pungent, bitter and warm in nature. It is an excellent analgesic Chinese herbal medicine and can enhance the analgesic effect of acupuncture in the treatment of painful diseases such as headache, stomachache and flank pain. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 Fibrinogen content in rat femoral artery.

[0025] The accompanying drawings are used to provide further understanding of the present invention and constitute a part of the specification. They are used to explain the present invention together with the embodiments of the present invention and do not constitute a limitation of the present invention. DETAILED DESCRIPTION

[0026] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments; based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0027] Unless otherwise defined, all professional and scientific terms used herein have the same meanings as those familiar to those skilled in the art. In addition, any methods and materials similar or equivalent to those described herein may be applied to the present invention. The preferred implementation methods and materials described herein are for demonstration purposes only and are not intended to limit the content of this application.

[0028] The experimental methods in the following examples are conventional methods unless otherwise specified; the experimental materials and test strains used in the following examples are purchased from commercial channels unless otherwise specified.

[0029] Example 1

[0030] A kind of medicine composition for acupuncture treatment

[0031] The pharmaceutical composition includes the following components in parts by weight: The pharmaceutical composition includes the following components in parts by weight: 20 parts of moxa, 50 parts of smilax china, 30 parts of radix spatholobi, 50 parts of salvia miltiorrhiza, 10 parts of safflower, 40 parts of corydalis yanhusuo, and 50 parts of high-proof liquor.

[0032] The present invention also provides a method for preparing a pharmaceutical composition for acupuncture treatment, the preparation method comprising the following steps:

[0033] (1) Preparation of extract: Mix and grind Lithospermum officinale, Rhubarb and Sanguisorba officinalis, soak and extract with strong liquor, filter and concentrate to obtain extract;

[0034] (2) Preparation of moxibustion medicine column: the drug composition is mixed and crushed, and an adhesive paste is added to prepare a moxibustion medicine column;

[0035] (3) Preparation of Corydalis yanhusuo pills: Crush the Corydalis yanhusuo and mix it with auxiliary materials, and make it into pills with refined honey.

[0036] Furthermore, in step (1), the alcohol content of the liquor is 52-60 degrees.

[0037] Furthermore, the immersion extraction time in step (1) is 24-48 hours.

[0038] Furthermore, the paste in step (2) is made from Schisandra chinensis and Galla chinensis.

[0039] Furthermore, the diameter of the drug column in step (2) is 1.5-2.0 cm.

[0040] Furthermore, the weight of the pills in step (3) is 3-5 grams.

[0041] Furthermore, the preparation method also uses the following tools: a large hand pad with a diameter of 28 cm (round), a small hand pad with a diameter of 17 cm, a 40×40 cm pure cotton white cloth (square), and a ceramic bowl with a bowl mouth diameter of 11.5 cm.

[0042] Example 2

[0043] A kind of medicine composition for acupuncture treatment

[0044] The pharmaceutical composition comprises the following components in parts by weight: 30 parts of moxa, 40 parts of smilax glabra, 35 parts of radix spatholobi, 40 parts of salvia miltiorrhiza, 20 parts of safflower, 30 parts of corydalis, and 80 parts of high-proof liquor.

[0045] The present invention also provides a method for preparing a pharmaceutical composition for acupuncture treatment, and the preparation method is carried out with reference to Example 1.

[0046] Example 3

[0047] A kind of medicine composition for acupuncture treatment

[0048] The pharmaceutical composition comprises the following components in parts by weight: 40 parts of moxa, 30 parts of smilax glabra, 40 parts of radix spatholobi, 30 parts of salvia miltiorrhiza, 30 parts of safflower, 20 parts of corydalis, and 110 parts of high-proof liquor.

[0049] The present invention also provides a method for preparing a pharmaceutical composition for acupuncture treatment, and the preparation method is carried out with reference to Example 1.

[0050] Experimental Example 1

[0051] Effect of a medicine composition for acupuncture treatment on animals with qi and blood stasis model

[0052] 60 healthy adult SD rats, weighing 250-300g, half male and half female, were selected. They were randomly divided into Example 1 group, Example 2 group, and Example 3 group, with 20 rats in each group; the rats in each group were subcutaneously injected with epinephrine and soaked in ice water to establish a qi and blood stasis model, specifically, the rats were subcutaneously injected with epinephrine 0.8mg / kg, twice a day, for 2 consecutive days; at the same time, the rats were soaked in ice water for 5min, once a day, for 2 consecutive days; each group was administered with the pills prepared in Example 1, Example 2 and Example 3, once a day, and the femoral artery blood of the rats was taken to detect the fibrinogen content after continuous administration for 14 days.

[0053] Result analysis: Figure 1 As shown, the fibrinogen content of rats in Example 1-3 groups was at a low level, among which the content in Example 2 group was the lowest, followed by Example 1 group and Example 3 group.

[0054] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

[0055] The present invention and its embodiments are described above, and such description is not restrictive. The drawings show only one embodiment of the present invention, and the actual structure is not limited thereto. In short, if ordinary technicians in the field are inspired by it, without departing from the purpose of the invention, they can design a structure and embodiment similar to the technical solution without creativity, which should belong to the protection scope of the present invention.

Claims

1. A pharmaceutical composition for acupuncture treatment, characterized in that: The pharmaceutical composition comprises the following components in parts by weight: 10-60 parts of moxa, 20-70 parts of smilax glabra, 10-50 parts of radix spatholobi, 20-60 parts of salvia miltiorrhiza, 5-50 parts of safflower, 5-45 parts of corydalis, and 20-200 parts of high-proof liquor.

2. The pharmaceutical composition for acupuncture treatment according to claim 1, characterized in that: The pharmaceutical composition comprises the following components in parts by weight: 15-50 parts of moxa, 30-60 parts of smilax glabra, 20-40 parts of radix spatholobi, 30-60 parts of salvia miltiorrhiza, 10-40 parts of safflower, 10-40 parts of corydalis, and 30-150 parts of high-proof liquor.

3. The pharmaceutical composition for acupuncture treatment according to claim 2, characterized in that: The pharmaceutical composition comprises the following components in parts by weight: 20-40 parts of moxa, 30-50 parts of smilax glabra, 30-40 parts of radix spatholobi, 30-50 parts of salvia miltiorrhiza, 10-30 parts of safflower, 20-40 parts of corydalis, and 50-110 parts of high-proof liquor.

4. A method for preparing the acupuncture treatment pharmaceutical composition according to claim 3, characterized in that: The preparation method comprises the following steps: (1) Preparation of extract: Mix and grind Lithospermum officinale, Rhubarb and Sanguisorba officinalis, soak and extract with strong liquor, filter and concentrate to obtain extract; (2) Preparation of moxibustion medicine column: the drug composition is mixed and crushed, and an adhesive paste is added to prepare a moxibustion medicine column; (3) Preparation of Corydalis yanhusuo pills: Crush the Corydalis yanhusuo and mix it with auxiliary materials, and make it into pills with refined honey.

5. The pharmaceutical composition for acupuncture treatment according to claim 4, characterized in that: In the step (1), the alcohol content of the liquor is 52-60 degrees.

6. The pharmaceutical composition for acupuncture treatment according to claim 5, characterized in that: The immersion extraction time in step (1) is 24-48 hours.

7. The pharmaceutical composition for acupuncture treatment according to claim 6, characterized in that: The paste in step (2) is made from Schisandra chinensis and Galla chinensis.

8. The pharmaceutical composition for acupuncture treatment according to claim 7, characterized in that: The diameter of the drug column in step (2) is 1.5-2.0 cm.

9. The pharmaceutical composition for acupuncture treatment according to claim 8, characterized in that: The weight of the pills in step (3) is 3-5 grams.

10. The pharmaceutical composition for acupuncture treatment according to claim 9, characterized in that: The preparation method also uses the following tools: a large hand pad with a diameter of 28 cm (round), a small hand pad with a diameter of 17 cm, a 40×40 cm pure cotton white cloth (square), and a ceramic bowl with a bowl mouth diameter of 11.5 cm.

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