Skin care composition containing liquid crystal structure and preparation method thereof

Abstract

The invention provides a skin care composition containing a liquid crystal structure and a preparation method thereof, and the composition comprises the following components by mass: 0.3-0.5% of a main emulsifier; 0.35%-2.5% of a co-emulsifier; 0.4%-3.5% of grease; 0.1%-0.5% of a water phase thickening agent; 4-11% of a humectant; and the balance of water. The liquid crystal structure in the composition has good stability, after a 30-day / 50-DEG C stability test, the retention rate of the liquid crystal structure is 80% or above, the liquidity is good, and when the composition is used as mask liquid, mask cloth can be rapidly and fully soaked in the mask liquid during coating or filling. Compared with a skin care composition without a liquid crystal structure, the water retention capacity of the skin is obviously improved after the composition is used, and meanwhile, a good soothing effect is achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of skin care, and in particular to a skin care composition containing a liquid crystal structure and a preparation method thereof. Background Art

[0002] Because the liquid crystal structure is similar to the structure of the skin's stratum corneum, skin care products with a liquid crystal structure can not only effectively repair and strengthen the skin's barrier function and improve skin moisturizing properties, but can also help the conduction and penetration of active substances, greatly improving the utilization of active ingredients and enhancing the efficacy of skin care products.

[0003] At present, liquid crystal technology in skin care products is mostly used in creams, which form a cream-like system containing lipid lamellar liquid crystal structure by adding a high content of liquid crystal emulsifier, thereby giving the cream better moisturizing properties.

[0004] However, there are few studies on the use of liquid crystal compositions in facial mask liquids. On the one hand, this may be because the viscosity of the facial mask liquid is low and the fluidity is high, which can easily lead to the destruction of the liquid crystal structure. On the other hand, in the liquid crystal system, liquid crystal emulsifiers need to be added in higher amounts to form a more stable liquid crystal system. If the amount of liquid crystal emulsifier added to the facial mask liquid is too much, it will easily cause the overall viscosity of the facial mask liquid to increase, making it difficult to fully soak the mask when applied, and the skin feel is not good, and it is easy to feel thick and sticky, which will significantly reduce consumers' desire to buy. Summary of the invention

[0005] In view of this, the present invention provides a skin care composition containing a liquid crystal structure and a preparation method thereof. The liquid crystal structure in the composition has good stability. After a 30-day / 50°C stability test, the retention rate of the liquid crystal structure is above 80%, and the fluidity is good. When used as a facial mask liquid, the facial mask cloth can be quickly and fully soaked during coating or filling. Compared with a skin care composition without a liquid crystal structure, the skin's water retention capacity is significantly improved after use, and it also has a good soothing effect.

[0006] Its specific technical scheme is as follows: The present invention provides a skin care composition containing a liquid crystal structure, which comprises the following components by mass percentage: Main emulsifier 0.3%~0.5%; Emulsifier 0.35%~2.5%; Oil 0.4%~3.5%; Water phase thickener 0.1%~0.5%; Moisturizer 4-11%; Remaining amount of water.

[0007] Furthermore, the skin care composition containing a liquid crystal structure comprises the following components by mass percentage: Main emulsifier 0.3~0.5%; Emulsifier 0.4%~1.2%; Oil 0.5-3%; Water phase thickener 0.18~0.27%; Moisturizer 5.05~10.2%; Remaining amount of water.

[0008] Among them, the main emulsifier comprises a mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid. Furthermore, in the mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid, the content of polyglycerol-3-cetyl ether is 85-95%, the content of sesame seed oil is 4-10%, and the content of 2-hydroxysuccinic acid is 1%-8%. Furthermore, the primary emulsifier is a mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid and Montanov L (Sepico (Shanghai) Special Chemicals Co., Ltd., INCI name is C14-22 alcohol, C12-20 alkyl glucoside), wherein the content of the mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid is 0.25% to 0.4%, and the content of Montanov L (C14-22 alcohol, C12-20 alkyl glucoside of Sepico (Shanghai) Special Chemicals Co., Ltd.) is 0.05% to 0.1%, for example, the content of the mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid is 0.4%, and the content of Montanov L is 0.1%.

[0009] Furthermore, in order to form a stable liquid crystal system with the primary emulsifier, the composition further comprises an auxiliary emulsifier, wherein the auxiliary emulsifier is one or more of palmityl alcohol, stearyl alcohol, cetearyl alcohol, arachidyl alcohol, and behenyl alcohol. Preferably, the auxiliary emulsifier is cetearyl alcohol and / or behenyl alcohol, wherein the content of cetearyl alcohol is 0.4-1%, and the content of behenyl alcohol is 0.2-0.8%.

[0010] Furthermore, the skin care composition containing a liquid crystal structure may also contain other commonly used emulsifiers, such as LC-1688 liquid crystal emulsifier (Shanghai Lishengshengte Enterprise Development Co., Ltd., INCI name is caprylic / capric triglyceride, hydrogenated lecithin, phytosterols, glyceryl stearate, PEG-30 phytosterol, cetyl alcohol, stearyl alcohol, cholesterol, behenyl alcohol), biomimetic liquid crystal emulsifier (Shanghai Zhina Technology INCI name is cetearyl alcohol, phytosterols, glyceryl isostearate, hydrogenated lecithin), EMULIUM MELLIFERA MB (France Gattefossé, INCI name is polyglyceryl-6 distearate, jojoba esters, polyglyceryl-3 beeswax acid ester, cetyl alcohol), Montanov 202 (Sepico (Shanghai) Special Chemicals Co., Ltd., INCI name is arachidyl alcohol, behenyl alcohol, arachidyl glucoside) and Montanov 68 MB (Sepico (Shanghai) Special Chemicals Co., Ltd., INCI name is cetearyl alcohol, cetearyl glucoside) or one or more.

[0011] The oil is selected from commonly used oils: one or more of silicone oils, vegetable oil esters and synthetic oils, such as polydimethylsiloxane, caprylic / capric triglyceride, ethylhexyl palmitate, squalane, hydrogenated polyisobutene, dicaprylyl carbonate, octyldodecanol, tea seed oil, meadowfoam seed oil, olive fruit oil, green tea seed oil, camellia seed oil, triethylhexanoin, hexyldecanol, hydrogenated polydecene, and cetyl ethylhexanoate.

[0012] Preferably, the oil is selected from one or more of dimethicone, ethylhexyl palmitate, squalane, hydrogenated polyisobutene, and caprylic / capric triglyceride.

[0013] The aqueous phase thickener is selected from one or more of acrylic acid (esters) / C10-30 alkyl acrylate cross-polymer, xanthan gum, hydrolyzed sclerotium gum, carbomer, gellan gum, hydroxyethyl cellulose, ammonium acryloyldimethyl taurate / VP copolymer, polyacrylate cross-polymer-6 / tert-butyl alcohol / water, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, sodium polyacrylate, sodium alginate, PEG-240 / HDI copolymer bis-decyltetradecyl alcohol polyether-20 ether. Further, the aqueous phase thickener is selected from one or more of acrylic acid (esters) / C10-30 alkyl acrylate cross-polymer, carbomer, xanthan gum, and hydrolyzed sclerotium gum.

[0014] The moisturizing agent is selected from one or more of butylene glycol, glycerol, 1,2-hexanediol, 1,3-propylene glycol, dipropylene glycol, glycerol polyether-26, PEG / PPG-17 / 6 copolymer, 1,2-pentanediol, caprylyl glycol, erythritol, polyethylene glycol-32, urea, polyethylene glycol-75, PPG-5-cetyl alcohol polyether-20, sodium polyglutamate, methyl propanediol, glycerol polyacrylate, PPG-9 diglycerol ether, and trehalose. Further, the moisturizing agent is selected from a mixture of glycerol, butylene glycol, and 1,2-hexanediol, wherein the glycerol content is 2-4.5%, the butylene glycol content is 3-5.5%, and the 1,2-hexanediol content is 0.05-0.2%.

[0015] Furthermore, the viscosity of the skin care composition containing a liquid crystal structure ranges from 1000 to 5000 cps.

[0016] Furthermore, the skin care composition containing a liquid crystal structure comprises active ingredients conventionally found in cosmetic raw materials, such as antioxidants, whitening agents, soothing agents, anti-wrinkle agents, and oil-controlling and anti-acne agents.

[0017] Furthermore, the active ingredient is selected from one or more of panthenol, betaine, dipotassium glycyrrhizinate, allantoin, tocopherol acetate, niacinamide, yeast fermentation product filtrate, yeast lysate, rose extract, lactobacillus fermentation product, glacier water, hot spring water, ascorbyl glucoside, caffeine, biosaccharide gum, bisabolol / ginger root extract, quaternary ammonium salt-73, tocopherol (vitamin E), highland barley beta-glucan, inositol, purslane extract, Centella asiatica extract, tea extract, Terminalia chebula fruit extract, sodium hyaluronate, hyaluronic acid, and ceramide, and the added amount is the conventional added amount.

[0018] Furthermore, the skin care composition containing a liquid crystal structure comprises a pH regulator, a chelating agent, and a solubilizing agent, and the added amounts thereof are conventional.

[0019] The present invention also provides a liquid crystal facial mask liquid, wherein the liquid crystal facial liquid contains 0.1% to 99.9% of the skin care composition containing a liquid crystal structure.

[0020] The present invention also provides a method for preparing a skin care composition containing a liquid crystal structure, by which a skin care composition with uniform particle size and stable lattice can be obtained when the amount of primary emulsifier added is relatively low. The method for preparing a skin care composition containing a liquid crystal structure comprises the following steps: 1) Heat 0.3-0.5% of the main emulsifier, 0.35%-2.5% of the auxiliary emulsifier, and 2-4.5% of the moisturizer to 60-85°C, dissolve them completely and mix them evenly, then add 0.4%-3.5% of the oil, dissolve them completely and mix them evenly; 2) Add 1-5% water to the mixture obtained in step 1) and mix well at 60-85°C; 3) Mix the remaining water, 0.1% to 0.5% aqueous phase thickener, and 2 to 5.5% moisturizer, and heat to 60-85°C and mix evenly; add the mixture from step 2) and mix evenly at 60-85°C; 4) Cool down to 40-55℃, add pH adjuster, 0-1% moisturizer and mix well.

[0021] Among them, adding a moisturizer in step 1) can change the characteristics of the dispersion medium in the system, increase the affinity of the oil and emulsifier in the aqueous dispersion medium, and help improve the dispersion of the oil and emulsifier in the aqueous phase, and is more conducive to forming a liquid crystal structure with uniform particle size. Preferably, it is a moisturizer with a high hydroxyl content, such as glycerol, and the content is preferably 2.4-4%.

[0022] The amount of water added in step 2) has a great influence on the formation of liquid crystal: the amount of water added in this step affects the formation of the liquid crystal structure. If the amount of water added is too high, sufficient liquid crystal cannot be formed. If too little water is added, it is not conducive to forming a uniform system.

[0023] The moisturizing agent added in step 3) is a moisturizing agent with good thermal stability, such as butanediol, and the content is preferably 3-5%.

[0024] Furthermore, in step 3), ingredients with high stability such as antioxidants and chelating agents may be added.

[0025] The moisturizing agent added in step 4) is a moisturizing agent with poor thermal stability, such as 1,2-hexanediol, and the content is preferably 0.05-0.2%.

[0026] Furthermore, ingredients with poor stability, such as pH regulators, chelating agents, and active ingredients, may also be added in step 4).

[0027] Wherein, the main emulsifier is selected from LC-1688 liquid crystal emulsifier (Shanghai Lishengshengte Enterprise Development Co., Ltd., INCI name is caprylic / capric triglyceride, hydrogenated lecithin, phytosterols, glyceryl stearate, PEG-30 phytosterol, cetyl alcohol, stearyl alcohol, cholesterol, behenyl alcohol), bionic liquid crystal (Shanghai Zhina Technology INCI name is cetearyl alcohol, phytosterols, glyceryl isostearate, hydrogenated lecithin), EMULIUM MELLIFERA MB (France Gattefossé, INCI name is polyglyceryl-6 distearate, jojoba esters, polyglyceryl-3 beeswax ester, cetyl alcohol), Montanov 202 (Sepico (Shanghai) Special Chemicals Co., Ltd., INCI name is arachidyl alcohol, behenyl alcohol, arachidyl glucoside) and Montanov 68MB (Sepico (Shanghai) Special Chemicals Co., Ltd., INCI name is cetearyl alcohol, cetearyl glucoside), a mixture of polyglyceryl-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid, Montanov L (Sepico (Shanghai) Special Chemicals Co., Ltd., INCI name is C14-22 alcohol, C12-20 alkyl glucoside). Preferably, the primary emulsifier comprises a mixture of polyglyceryl-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid, and further, the content of polyglyceryl-3-cetyl ether in the mixture of polyglyceryl-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid is 85-95%, the content of sesame seed oil is 4-10%, and the content of 2-hydroxysuccinic acid is 1%-8%. Further, the main emulsifier is a mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid and Montanov L (Sepico (Shanghai) Special Chemicals Co., Ltd., INCI name is C14-22 alcohol, C12-20 alkyl glucoside), wherein the content of the mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid is 0.25% to 0.4%, and the content of Montanov L is 0.05% to 0.1%, for example, the content of the mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid is 0.4%, and the content of Montanov L is 0.1%. The use of the above two emulsifiers can further improve the stability of the liquid crystal structure.

[0028] In order to form a stable liquid crystal system adapted to a skin care composition containing a liquid crystal structure with the primary emulsifier, the content of the auxiliary emulsifier is 0.4% to 1.2%, and comprises one or more of palmityl alcohol, stearyl alcohol, cetearyl alcohol, arachidyl alcohol, and behenyl alcohol. Preferably, the auxiliary emulsifier is cetearyl alcohol and / or behenyl alcohol, wherein the content of cetearyl alcohol is 0.4 to 1%, and the content of behenyl alcohol is 0.2 to 0.8%.

[0029] Beneficial Effects (1) The skin care composition containing a liquid crystal structure provided by the present invention is prepared by combining a mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid with cetearyl alcohol or behenyl alcohol. The prepared skin care composition can form a liquid crystal structure with uniform particle size and stable lattice. The stability of the liquid crystal structure is good. After a 30-day / 50°C stability test, the retention rate of the liquid crystal structure in the mask liquid is above 80%.

[0030] (2) The skin care composition containing a liquid crystal structure provided by the present invention has good fluidity and low viscosity, and can quickly and fully soak the mask cloth. When applied, the mask liquid is soft and non-greasy, and is extremely easy to absorb. The residue is very light, and there will be a light feeling after absorption. When used with the mask cloth, the application process will feel gentle and non-oppressive, and the skin will feel soft and delicate after application, and the processing performance is good. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 :Photographs of liquid crystal structures (a) Polarized light microscope photograph of the composition of Example 1 (objective lens 50 times, eyepiece 10 times) (b) Polarized light microscope photograph of the composition of Comparative Example 2 (objective lens 50 times, eyepiece 10 times) Figure 2 : Comparison of the wetting of the compositions of Example 1 and Comparative Example 2. Left in the figure: membrane cloth + composition of Example 1. Right in the figure: membrane cloth + composition of Comparative Example 2. DETAILED DESCRIPTION

[0032] The present invention is further described below by way of examples, but the present invention is not limited to the scope of the examples.

[0033] 1. Preparation of skin care composition containing liquid crystal structure Glycerol-3-cetyl ether, sesame seed oil, and 2-hydroxysuccinic acid were purchased from Guangzhou Bochi Biotechnology Co., Ltd.

[0034] Montanov L (INCI name: C14-22 alcohol, C12-20 alkyl glucoside) was purchased from Sepco (Shanghai) Special Chemicals Co., Ltd., and cetearyl alcohol and cetearyl glucoside liquid crystal emulsifiers were purchased from Sepco (Shanghai) Special Chemicals Co., Ltd. Montanov 68 MB.

[0035] Example 1 1) Take 85% by weight of polyglycerol-3-cetyl ether, 10% by weight of sesame seed oil, and 5% by weight of 2-hydroxysuccinic acid to prepare a primary emulsifier, heat 0.5 parts by weight of the primary emulsifier, 0.8 parts by weight of cetearyl alcohol, and 4 parts by weight of glycerol to 60-85°C, and after confirming that the materials are dissolved and mixed evenly, add 1.8 parts of oil (0.3 parts by weight of polydimethylsiloxane, 1.5 parts by weight of caprylic capric triglyceride), and at 60-85°C, confirm that the materials are completely dissolved and mixed evenly.

[0036] 2) Add 5 parts of water to the mixture obtained in step 1) and mix well at 60-85°C.

[0037] 3) Evenly mix the remaining amount of water, 0.27 parts of aqueous phase thickener (0.1 parts of xanthan gum, 0.05 parts of hydrolyzed sclerotium gum, 0.12 parts of acrylate C10-30 alkyl acrylate cross-linked polymer), 3 parts of butylene glycol, p-hydroxyacetophenone, disodium EDTA, etc., stir and heat to 60-85°C, keep warm for 15-25 minutes, and confirm that the materials are evenly mixed; add the mixture of step 2), homogenize at 60-85°C, and mix evenly.

[0038] 4) Cool down to 40-55°C with stirring, add arginine, 0.15 parts of 1,2-hexanediol), and active ingredients while stirring, and mix well.

[0039] Embodiment 2-7 The preparation method is the same as that of Example 1, except that the content of each component in the skin care composition containing a liquid crystal structure is different. The amount is adjusted to 100 parts with water, and the formula of each example is as follows.

[0040] Table 1: Implementation of formulations 1-7

[0041] Comparative Examples 1-11 Except for the following changes in Example 1, the contents of other formulation components or methods are the same as in Example 1, and water is used to adjust the mass to 100 parts. The changes in each comparative example are as follows: Comparative Example 1 The preparation method and other components are the same as those in Example 1, except that the content of the primary emulsifier is 0.6 parts.

[0042] Comparative Example 2 The preparation method and other components are the same as in Example 1, except that the main emulsifier is cetearyl alcohol and cetearyl glucoside liquid crystal emulsifier. Comparative Example 3 The preparation method and other components are the same as those in Example 1, except that the content of the primary emulsifier is 0.2 parts.

[0043] Comparative Example 4 The preparation method and other components are the same as those in Example 1, except that the content of the co-emulsifier is 0.3 parts.

[0044] Comparative Example 5 The preparation method and other components are the same as those in Example 1, except that the content of the co-emulsifier is 2.6 parts.

[0045] Comparative Example 6 The preparation method and other components are the same as those in Example 1, except that the fat content is 0.3 parts.

[0046] Comparative Example 7 The preparation method and other components are the same as those in Example 1, except that the fat content is 4 parts.

[0047] Comparative Example 8 The preparation method and other components are the same as those in Example 1, except that 0.3 parts of the main emulsifier is added, wherein 80% of polyglycerol-3-cetyl ether, 15% of sesame seed oil and 5% of 2-hydroxysuccinic acid are mixed.

[0048] Comparative Example 9 The preparation method and other formulas are the same as those in Example 1. The skin care composition containing a liquid crystal structure is prepared by a common water-oil homogenization emulsification method.

[0049] The specific method is: 1) Mix 0.5 parts of primary emulsifier, 0.8 parts of auxiliary emulsifier and 1.8 parts of oil, heat to 60-85℃, and make sure the materials are dissolved and mixed evenly; 2) Mix the remaining water, 0.27 parts of aqueous phase thickener, glycerin, butylene glycol, antioxidant, chelating agent, etc. evenly, stir and heat to 60-85°C, keep warm for 15-25 minutes, and make sure that the materials are evenly mixed; add the mixture in step 1), homogenize at 60-85°C, and mix evenly; 3) Stir and cool down to 40-55°C, add pH adjuster, 1,2-hexanediol and active ingredient while stirring, and mix well.

[0050] Comparative Example 10 The formula is the same as in Example 1, except that other commonly used emulsification methods are used. The specific method is: 1) Heat 0.5 parts of primary emulsifier, 0.8 parts of auxiliary emulsifier, and 4 parts of glycerol to 60-85°C and make sure the materials are dissolved and mixed evenly; 2) Heat 1.8 parts of oil to 60-85°C and make sure the material is dissolved and mixed evenly; 3) Mix water, aqueous phase thickener, butanediol, antioxidant, chelating agent, etc. evenly, stir and heat to 60-85°C, keep warm for 15-25 minutes, and make sure that the materials are evenly mixed; add the mixture of step 1), homogenize at 60-85°C, and mix evenly; add the mixture of step 2), homogenize at 60-85°C, and mix evenly; 4) Stir and cool down to 40-55°C, add pH adjuster, 1,2-hexanediol and other active ingredients while stirring, and mix well.

[0051] Comparative Example 11 The other steps of the formula and preparation method are the same as those of Example 1, except that 10 parts of water are added in step 2).

[0052] Table 2: Ingredients and contents of the modified parts of the formula of Comparative Examples 1-8

[0053] II: Related tests of Examples 1-8 and Comparative Examples 1-11: 1) Observation and verification method of liquid crystal structure: Using a sampling polarizing microscope, take the liquid crystal mask liquid samples of the embodiment and the comparative example respectively, observe the quantity, morphological structure and integrity of the liquid crystals formed in the samples under the polarizing microscope, take photos and record them, as shown in Table 3 below.

[0054] If the number of LCDs in the window is more than 120, then +++ If the number of LCDs in the window is more than 50, then ++ If the number of liquid crystals in the window is less than 20, it is +. "+++" meets the quantity requirements of the composition containing liquid crystal structure.

[0055] 2) Liquid crystal stability test: High temperature resistance test: In order to verify the stability of the liquid crystal structure, the samples of the embodiment and the comparative example were placed at 50° C. for 1 month, and observed again under a polarizing microscope to compare the retention rate of the liquid crystal structure.

[0056] The liquid crystal composition with good high temperature test results is filled into a mask and then the liquid crystal structure stability is evaluated: Filling the mask: fold the spunlace non-woven membrane cloth, put it into the mask bag, fill it with about 30ml (28±2ml) of mask liquid, and seal the mask bag.

[0057] After storing for one month, the film liquid was squeezed out and the retention rate of the liquid crystal structure was compared.

[0058] 3) Liquid crystal mask composition infiltration test: Used to simulate and evaluate the ease of mask coating. Use spunlace nonwoven mask cloth, take 0.20g of each membrane cloth of the same material, and drip 0.40g of the membrane liquid of each embodiment and comparative example at the same time, and observe the membrane liquid infiltration within 30s. If the membrane liquid can completely infiltrate the membrane cloth within 30s, it is yes, otherwise it is no. The exemplary comparison photos of the infiltration of Example 1 and Comparative Example 2 are shown in Figure 2 .

[0059] The above test results are shown in Table 3 Table 3: Results of effect testing of Examples 1-7 and Comparative Examples 1-11

[0060] Results Analysis The skin care compositions containing liquid crystal structures in Examples 1-7 form a large number of liquid crystals of uniform size, and after high temperature stability tests and filling and storage tests, the retention rate of the liquid crystal structure can reach more than 70%, and the composition has good fluidity. When used as a facial mask liquid, it can quickly and fully soak the mask cloth.

[0061] Comparative Example 1 If the content of the main emulsifier in the liquid crystal skin care composition is high, the formed composition cannot effectively wet the film cloth and fails the wetting test.

[0062] Comparative Example 2 When other commonly used liquid crystal emulsifiers are used alone as the main emulsifier, if the added amount is not high, no liquid crystal structure can be observed in the composition, the film cloth cannot be effectively wetted, and the wetting test fails.

[0063] Comparative Example 3 If the content of the primary emulsifier is too low, the amount of liquid crystals formed in the composition will be small, the particle size will be uneven, and the high-temperature structure retention rate of the liquid crystal will be low.

[0064] Comparative Example 4 If the content of the co-emulsifier is too low, the amount of liquid crystal in the liquid crystal composition is small, the particle size is uneven, and the high-temperature structure retention rate of the liquid crystal is low.

[0065] Comparative Example 5 If the content of the co-emulsifier is too high, the liquid crystal composition cannot pass the wettability test and the liquid crystal facial mask liquid cannot be obtained.

[0066] Comparative Example 6 If the oil content is too low, the amount of liquid crystal formed in the liquid crystal composition will be small and the high temperature structure retention rate of the liquid crystal will be low.

[0067] Comparative Example 7 If the oil content is too high, the particle size of the liquid crystal structure in the liquid crystal composition will be uneven, the high-temperature structure retention rate of the liquid crystal will not be high, water and oil will separate after 2 weeks at a high temperature of 50°C, and the composition will fail the wettability test.

[0068] Comparative Example 8 The emulsifier is selected from a mixture of 80% polyglycerol-3-cetyl ether, 15% sesame seed oil, and 5% 2-hydroxysuccinic acid. The content of the main emulsifier varies, the amount of liquid crystal is relatively small, and the high-temperature structure retention rate of the liquid crystal is lower than that of the example sample.

[0069] Comparative Example 9 Water-oil homogeneous emulsification is used, the amount of liquid crystal is very small, and the high-temperature structure retention rate of liquid crystal is low.

[0070] Comparative Example 10 When other emulsification methods are used, the particle size of the liquid crystal structure formed is very uneven, and the high-temperature structure retention rate of the liquid crystal is low.

[0071] Comparative Example 11 If the water content added in step 1 is too high, a smaller amount of liquid crystals are formed.

[0072] Efficacy evaluation 1) Skin feel rating: 30 women aged 20-50 with relatively sensitive skin were selected, and the masks of Example 1 and Comparative Example 2 were used on half of their faces respectively. Immediate use experience: 90% of the testers preferred the mask of Example 1, which felt very gentle and soothing, soft and close to the skin during use, non-greasy and light residue after absorption, and very delicate and obviously brightened skin; experience 8 hours after use: 92% of the testers felt that the mask of Example 1 was more hydrated and had a more lasting moisturizing effect.

[0073] 2) Mildness score: 30 women applied the mask twice a week for 28 days. The testers reported that the mask of Example 1 was not sticky after application, was soft and close to the skin, and had a good skin feel. After use, it felt mild and non-irritating, and there were no adverse reactions such as facial irritation and allergies, and the skin did not feel any discomfort; after use, it felt that the dryness and tightness could be effectively improved, the skin felt moisturized and not rough, the skin felt more shiny, translucent, tender and delicate, the skin felt moisturized and nourished, the discomfort could be effectively relieved after use, the discomfort such as dry itching, stinging, and redness could be effectively relieved after use, the skin barrier felt strong, the skin was more tolerant and more stable after use, the skin dry lines and fine lines could be improved after use, the skin texture could be lightened after use, the skin felt tighter after use, the facial contour was tightened and lifted, the pores were smoothed and tightened after use, and the enlarged pores caused by sagging skin could be improved.

[0074] 3) Moisturizing rating: 30 women washed their right arms and marked out a test area of ​​3cm*3cm. Before the test began, sit quietly in a room at 25°C for 15 minutes, first test the TEWL value before applying the sample, then evenly apply 18mg of the sample on the test area, and then test the TEWL value of the skin after applying the sample after 1h, 2h, 4h and 8h. Compared with the TEWL value before applying the sample, the improvement rate of the skin's water retention capacity after applying the sample was examined. (TEWL, also known as transdermal water loss, is a common indicator reflecting the barrier function of the stratum corneum. The smaller the TEWL value, the slower the loss of water through the skin and the better the moisturizing effect.) The moisturizing test results of the masks of Example 1 and Comparative Example 2 are shown in Table 4: Table 4: Moisture retention test results of Example 1 and Comparative Example 2

[0075] Test data (improvement rate = (TEWL value of uncoated sample - TEWL （涂抹样品后1h、2h、4h、8h） ) / TEWL value when the sample is not applied*100%). As shown in Table 4, the use of the liquid crystal composition disclosed in the present invention can significantly improve the water retention capacity of the skin.

[0076] Although the specific embodiments of the present invention are described above, it should be understood by those skilled in the art that this is only for illustration and the protection scope of the present invention is defined by the appended claims. Those skilled in the art may make various changes or modifications to these embodiments without departing from the principles and essence of the present invention, but these changes and modifications all fall within the protection scope of the present invention.

Claims

1. A skin care composition containing a liquid crystal structure, characterized in that: Calculated by mass percentage, it includes the following components: Main emulsifier 0.3%~0.5%, Emulsifier 0.35%~2.5%, Oil 0.4%~3.5%, Water phase thickener 0.1%~0.5%, Moisturizer 4-11%, The balance is water; wherein the primary emulsifier comprises a mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid.

2. The skin care composition containing a liquid crystal structure according to claim 1, characterized in that: The oil content is 0.5-3%, the water phase thickener content is 0.18-0.27%, and the moisturizer content is 5.05-10.2%.

3. The skin care composition containing a liquid crystal structure according to claim 2, characterized in that: In the mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid, the content of polyglycerol-3-cetyl ether is 85-95%, the content of sesame seed oil is 4-10%, and the content of 2-hydroxysuccinic acid is 1%-8%.

4. The skin care composition containing a liquid crystal structure according to claim 1, characterized in that: The main emulsifier is a mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid and Montanov L, wherein the content of the mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid is 0.25% to 0.4%, and the content of Montanov L is 0.05% to 0.1%.

5. The skin care composition containing a liquid crystal structure according to claim 1, characterized in that: The content of the auxiliary emulsifier is 0.4% to 1.2%, and the auxiliary emulsifier is selected from one or more of palmityl alcohol, stearyl alcohol, cetearyl alcohol, arachidyl alcohol, and behenyl alcohol; preferably, the auxiliary emulsifier is cetearyl alcohol and / or behenyl alcohol, wherein the content of cetearyl alcohol is 0.4 to 1%, and the content of behenyl alcohol is 0.2 to 0.8%; the aqueous phase thickener is selected from acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, xanthan gum, hydrolyzed sclerotium gum, carbomer, gellan gum, hydroxyethyl cellulose, ammonium acryloyldimethyl taurate / VP copolymer, polyacrylate cross-linked polymer-6 / tert-butyl alcohol / water, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, sodium polyacrylate, sodium alginate, PEG-240 / HDI copolymer bis-decyltetradecyl alcohol polyether-20 One or more of ethers, further, the aqueous phase thickener is selected from one or more of acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, carbomer, xanthan gum, and hydrolyzed sclerotium gum; the humectant is selected from butylene glycol, glycerol, 1,2-hexanediol, 1,3-propylene glycol, dipropylene glycol, glycerol polyether-26, PEG / PPG-17 / 6 copolymer, 1,2-pentanediol, caprylyl glycol, erythritol, polyethylene glycol-32, urea, polyethylene glycol-75, PPG-5-cetyl alcohol polyether-20, sodium polyglutamate, methylpropylene glycol, glyceryl polyacrylate, PPG-9 diglycerol ether, and trehalose. Preferably, the humectant is selected from a mixture of glycerol, butylene glycol, and 1,2-hexanediol, wherein the glycerol content is 2-4.5%, the butylene glycol content is 3-5.5%, and the 1,2-hexanediol content is 0.05-0.2%.

6. The skin care composition containing a liquid crystal structure according to claim 4, further comprising other emulsifiers and active ingredients; wherein the other emulsifiers are selected from one or more of LC-1688 liquid crystal emulsifier, EMULIUM MELLIFERAMB, Montanov 202 and Montanov 68 MB, and biomimetic liquid crystal emulsifiers; and the active ingredient is selected from one or more of panthenol, betaine, dipotassium glycyrrhizinate, allantoin, tocopherol acetate, niacinamide, yeast fermentation product filtrate, yeast lysate, rose extract, lactobacillus fermentation product, glacial water, hot spring water, ascorbyl glucoside, caffeine, biosaccharide gum, bisabolol / ginger root extract, quaternary ammonium salt-73, tocopherol (vitamin E), highland barley beta-glucan, inositol, purslane extract, Centella asiatica extract, tea extract, Terminalia chebula fruit extract, sodium hyaluronate, hyaluronic acid, and ceramide.

7. A liquid crystal facial mask liquid, characterized in that: The liquid crystal face liquid contains 0.1% to 99.9% by mass of the skin care composition containing a liquid crystal structure as described in claims 1 to 6.

8. A method for preparing a skin care composition containing a liquid crystal structure, characterized in that: The preparation method comprises the following steps: 1) Heat 0.3-0.5% of the main emulsifier, 0.35%-2.5% of the auxiliary emulsifier, and 2-4.5% of the moisturizer to 60-85°C, dissolve them completely and mix them evenly, then add 0.4%-3.5% of the oil, dissolve them completely and mix them evenly; 2. Add 1-5% water to the mixture obtained in step 1) and mix well at 60-85°C; 3) Mix the remaining water, 0.1% to 0.5% aqueous phase thickener, and 2 to 5.5% moisturizer evenly, heat to 60-85°C, and mix evenly; add the mixture from step 2) and mix evenly; 4) Cool down to 40-55℃, add pH adjuster, 0-1% moisturizer and mix well.

9. The preparation method according to claim 8, characterized in that: in, The moisturizing agent added in step 1) is a moisturizing agent with a high hydroxyl content, preferably glycerol, with a content of 2.4-4%; The moisturizing agent added in step 3) is a moisturizing agent with good thermal stability, preferably butanediol, with a content of 3-5%; The moisturizing agent added in step 4) is a moisturizing agent with poor thermal stability, preferably 1,2-hexanediol, with a content of 0.05-0.2%.

10. The preparation method according to claim 8, characterized in that: The primary emulsifier is selected from one or more of poly LC-1688 emulsifier, EMULIUM MELLIFERA MB emulsifier, Montanov 202 emulsifier, a mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid, Montanov L emulsifier, and a biomimetic liquid crystal emulsifier; preferably, the primary emulsifier is selected from a mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid, wherein the content of polyglycerol-3-cetyl ether in the mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid is 85-95%, sesame seed oil is 4-10%, and 2-hydroxysuccinic acid is 1%-8%; further, the primary emulsifier is a mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid and Montanov L emulsifier. L, the content of the mixture of polyglycerol-3-cetyl ether, sesame seed oil and 2-hydroxysuccinic acid is 0.25% to 0.4%, and the content of Montanov L is 0.05% to 0.1%; the co-emulsifier includes one or more of palmityl alcohol, stearyl alcohol, cetearyl alcohol, arachidyl alcohol and behenyl alcohol.

Images