Preparation method, equipment and system for a columnar material

Abstract

The present invention relates to the field of advanced manufacturing, and particularly to a preparation method, device and system for columnar materials. A digital light beam is projected onto the surface of a moving base column to enable rapid prototyping of photosensitive materials on the surface of the base column to construct a new type of columnar material, including: after slicing a three-dimensional digital model layer by layer, performing image segmentation on each layer of slice in combination with parameters such as the rotation speed of the base column, inputting the images into an optical engine in sequence to form a dynamic digital light beam, and projecting it onto the photosensitive material on the surface of the base column to enable rapid three-dimensional prototyping on the surface of the base column. The optimal historical printing conditions of different materials can be input into a fitting model to obtain fitting coefficients, so as to obtain optimal and stable printing condition data. The printing condition data includes: exposure time and light intensity, projection area, moving speed of the base column, etc.; among them, the movement of the base column includes rotation and translation. The present invention can be matched to realize the construction of multi-material complex curved surface structures, such as the intelligent integrated prototyping of single-layer or multi-layer complex columnar structures.

Description

Technical Field

[0001] The present invention relates to the field of advanced manufacturing, and particularly relates to a method, device and system for preparing columnar materials. Background Art

[0002] 3D printing, also known as additive manufacturing, is a technology that can directly manufacture three-dimensional solid objects based on digital models. It can produce customized products according to individual needs, meeting the requirements of personalized and small-batch production. It can manufacture complex internal structures, such as lattice structures, hollow structures, etc., which are difficult or impossible to achieve in traditional manufacturing. Some 3D printing technologies can simultaneously use composite materials with multiple hardnesses, colors or functions and different cells for uniform or gradient printing, and conduct targeted time and space treatment for each disease, slowly or rapidly releasing drugs at different times.

[0003] With the development of 3D printing technology, columnar materials, as a class of materials with special structures and properties, have become a research and application hotspot. These technologies can precisely control the microstructure of materials, thereby optimizing their macroscopic properties. Columnar materials refer to hollow or solid columnar structures, which show extensive application potential in multiple fields, including but not limited to aerospace, medical devices, building structure reinforcement, thermal management of electronic devices, etc. For example, in the biomedical field, columnar bone scaffolds can promote cell growth and tissue regeneration; in the aerospace field, lightweight and high-strength columnar structure materials can be used to manufacture components of aircraft and satellites.

[0004] Forming a new three-dimensional structure on the surface of columnar materials through additive manufacturing technology can support the research and development of a variety of innovative products and has significant market demand. Currently, it has been reported that an extrusion-based 3D printing technology is used for three-dimensional printing on the surface of columnar materials. However, due to the slow speed of extrusion-based 3D printing, the application of this technology is severely limited. The digital light processing 3D-based printing technology has characteristics such as fast speed, but this technology is usually used for printing three-dimensional structures on a plane and it is difficult to achieve printing complex 3D structures on curved surfaces such as the surface of columnar materials.

[0005] For example, patent application CN113679506A discloses a simple preparation method for 3D printing an inner wall micropatterned nerve conduit. This method prints "ink" in a writing-style 3D manner on a tungsten steel rod with a micropattern structure to prepare a nerve conduit with the ability to induce cell directional migration. However, the extrusion printing method used in this method is slow and only applicable to preparing nerve conduits with a single structure and morphology.

[0006] In addition, patent application CN110757799A also discloses a device and manufacturing process suitable for preparing nerve conduits. As the forming shaft rotates slowly, ink is coated on the sleeve through an extrusion head by reciprocating back and forth at high speed in the X-axis direction to prepare nerve conduits. However, the structural setting and operation of its printing instrument are too complex. It requires manual adjustment of the fixing rod, fixing seat, handwheel, etc. for positioning printing, and the operation is inconvenient.

[0007] For another example, CN116252477A also provides a multi-degree-of-freedom biological 3D printing system for in vitro reconstruction of curved tissues. It includes a six-degree-of-freedom motion device and a variety of extrusion kits. The six-degree-of-freedom motion device includes an X-axis moving platform and a Z-axis moving platform fixed to the mounting table, a Y-axis moving platform slidably mounted on the X-axis moving platform, an XY rotating axis slidably mounted on the Y-axis moving platform, a YZ rotating axis rotatably mounted on the XY rotating axis, an XZ rotating axis rotatably mounted on the YZ rotating axis, a cantilever slidably mounted on the Z-axis moving platform, and the extrusion kit is mounted on the cantilever. The extrusion kit can move above the XZ rotating axis to achieve printing on the curved surface of the XZ rotating axis.

[0008] However, these traditional stereolithography (SLA) solutions generally have problems such as cumbersome operation, low printing efficiency, and unstable multi-layer printing and forming.

[0009] Therefore, there is an urgent need for a method that can improve the printing efficiency and printing quality for complex columnar materials. Summary of the Invention

[0010] The object of the present invention is to provide a method, device, and system for preparing columnar materials, which can partially solve or alleviate the above deficiencies in the prior art and can improve printing efficiency and printing quality. In the present invention, through the innovation and coordination of technologies such as digital light processing, 3D image processing, automated control, and photocuring materials, a method, device, and system for rapidly 3D printing three-dimensional structures on the surface of columnar materials are developed, which has good application prospects.

[0011] In view of the problems involved in the background art, the present application has developed a personalized and customized multi-functional columnar material preparation device. The preparation device includes: a base column, the outer surface of which can adsorb a certain thickness of photocurable liquid; a sample adding element is arranged on the lower side of the base column, and the sample adding element is provided with a sample adding pool which can accommodate the photocurable liquid. At least a part of the base column is immersed in the sample adding pool, and the rotation speed of the base column is adjusted to match the curing time of different photocurable liquids. The light machine projects (or, a photo) a light with a specific pattern onto the base column, and the photocurable liquid will be cured on the base column according to the designed specific shape, so as to realize the preparation of a columnar material with a customizable, high-efficiency, and high-uniformity multi-layer complex structure. In other words, the present application proposes a rapid rotation 3D printing technology. For example, the rapid rotation 3D printing technology proposed by the present application can prepare one to multiple layers of nerve conduits with different compositions, structures, and morphologies according to actual needs. Different photocurable liquids with photoinitiators are printed on the outer surface of a base column with a diameter of 1-3 mm that has been subjected to different treatments, including but not limited to casting and freeze-drying. Through these treatments, different structures and morphologies can be customized as needed for the inner layer of the conduit, promoting the growth and migration of nerve cells, improving the mechanical properties of the conduit, and solving the problem that a single hydrogel cannot be sutured.

[0012] The printing technology of the present invention can customize the required pattern through computer software, and the digital light beam can be accurately focused on the printing area, with higher printing accuracy; the whole printing process is controlled by a computer, and the light intensity, rotation speed can be changed, and printing can be timed, and the operation is fast and simple.

[0013] To solve the above-mentioned technical problems, the present invention specifically adopts the following technical solutions: In the first aspect of the present invention, there is provided a method for preparing a columnar material, the method comprising: S001, obtaining a three-dimensional digital model of the columnar material; S002, performing layer-by-layer slicing on the three-dimensional digital model along the thickness direction to correspondingly obtain multiple slices; S003, obtaining a first slice image adapted to the preparation equipment of the columnar material according to the slice; wherein, the preparation equipment includes: a base column, and the base column is arranged to be able to rotate around its axial direction, the base column has a diameter and a working length, and the outer surface of the base column can adsorb a light-curing liquid layer of a certain thickness; an optical machine for projecting a digital light beam onto the outer surface of the base column, and the area effectively covered by the digital light beam on the base column is the projection working area; correspondingly, the first slice image is the pattern corresponding to after the slice is spread, and the height of the first slice image matches the circumference of the base column, and the width of the first slice image is adapted to the working length; S004, using a set segmentation method to segment along the width direction of the first slice image to obtain multiple second slice images, and the set segmentation method requires that the height of the second slice image matches the height of the projection working area, and the second slice image is associated with a corresponding projection order; S005, the base column rotates at a set rotation speed so that the second slice images are sequentially projected onto the outer surface of the base column according to the projection order, so that the light-curing liquid is sequentially formed according to the pattern on the second slice image under the projection of the corresponding digital light beam.

[0014] In some embodiments, the number of pixel rows of the first slice image satisfies a set slicing rule, and the slicing rule includes:

[0015] ; ; ; ; ;

[0016] Wherein, n max is the maximum number of pixel rows of the first slice image in the height direction, N H , Nw are respectively the maximum number of pixels of the projection working area of the digital light beam in the height direction and the width direction; H p 、W p Minute are respectively the height and width of the projection working area of the digital light beam; l is the working length, h pis the perimeter of the base column, d is the diameter.

[0017] In some embodiments, the thickness of one layer of the slices is , correspondingly, the pixel height of the first slice image of the first layer projected on the base column is ; the maximum pixel height of the first slice image of the layer.

[0018] In some embodiments, the first slice image is a grayscale image or a binary image. Correspondingly, S004 includes: sequentially extracting the lines formed by the pixel points of each row of the first slice image as subsets, where the black pixel points are recognized as the background of the second slice image, and the non-black pixel points are recognized as the pattern of the second slice image; creating a plurality of second slice images based on the black pixel points and the non-black pixel points respectively.

[0019] In some embodiments, the total number of the second slice images formed by the plurality of slices is:

[0020] ;

[0021] m is the number of the slices, is the thickness of one layer of the slices, n total is the total number of the second slice images of the three-dimensional digital model, n i is the i total number of the second slice images of the slice of the

[0022] In some embodiments, it further includes steps: S006, monitoring the photocuring efficiency of the photocuring liquid; S007, when the photocuring efficiency is less than the set photocuring efficiency, correcting the second slice image and the projection time delay, where the projection time delay refers to the time that a single second slice image stays on the base column; the steps of correcting the second slice image and the projection time delay include: merging at least two second slice images of the slices of the layer to be corrected to obtain a corrected slice image; where the layer to be corrected is the i layer, correspondingly the height of the corrected slice image is ; determining the projection time delay according to the corrected slice image, and the projection time delay is: , n i is the i total number of the corrected slice images of the slices of the layer to be corrected of the layer, and is the rotation speed.

[0023] In some embodiments, S005 further includes the steps of: selecting the printing conditions of the three-dimensional digital model according to the fitting model; wherein, the printing conditions include: the thickness of the slice, the printing time of one layer of the slice, the light intensity, and the diameter of the base column; the fitting model includes:

[0024] ; wherein, is the thickness, is the fitting coefficient, is the printing time, is the light intensity, is the diameter.

[0025] The present invention correspondingly provides a preparation system for columnar materials. The system includes: a model acquisition module for acquiring a three-dimensional digital model of the columnar materials; a slicing module for performing hierarchical slicing on the three-dimensional digital model in the thickness direction to correspondingly obtain multiple slices; a first image acquisition module for acquiring a first slice image adapted to the preparation equipment of the columnar materials according to the slice; wherein, the preparation equipment includes: a base column, and the base column is arranged to be able to rotate around its axial direction. The base column has a diameter and a working length, and the outer surface of the base column can adsorb a certain thickness of photocurable liquid; an optical machine for projecting a digital light beam onto the surface of the base column, and the area where the digital light beam effectively covers the base column is the projection working area; correspondingly, the first slice image is the pattern corresponding to the spread slice, and the height of the first slice image matches the circumference of the base column, and the width of the first slice image is adapted to the working length; a second image acquisition module for using a set segmentation method to segment the first slice image in the width direction to obtain a plurality of second slice images. The set segmentation method requires that the height of the second slice image matches the projection working area, and the second slice image is associated with a corresponding projection order; a printing module for controlling the base column to rotate at a set rotation speed so that the second slice images are sequentially projected onto the outer surface of the base column according to the projection order, so that the photocurable liquid is sequentially formed according to the pattern on the second slice image under the projection of the corresponding digital light beam.

[0026] The present invention also provides a preparation device for columnar materials, comprising: a base column, the base column having a diameter and a length, and the base column having a curved outer surface; a sample adding element, the sample adding element being capable of accommodating a photocurable liquid; wherein, the sample adding element has a sample adding pool for accommodating the photocurable liquid, and the base column is arranged such that the outer surface can be at least partially immersed in the photocurable liquid; or, the sample adding element has at least one nozzle, and the nozzle can spray the photocurable liquid onto the outer surface; a supporting element, the supporting element being used for supporting the base column and capable of driving the base column to rotate around its axis at a set speed, and during the rotation of the base column, the outer surface can adsorb and form a photocurable liquid layer with a certain thickness; an optical machine, for projecting a digital light beam onto the surface of the base column; there is a first distance between the projection end of the optical machine and the surface of the base column at the initial printing moment; a moving element, the moving element being used for driving the base column to move along the projection direction; wherein, when a structural layer with a first thickness grows on the base column, the moving element can drive the base column to move so that the distance between the projection end and the outer surface remains or is approximately the first distance.

[0027] In some embodiments, it further comprises: a heating device, the heating device being used for heating the base column and / or the sample adding pool; and / or, the preparation device further comprises: a photographing device, the photographing device being used for collecting image information of the base column.

[0028] Beneficial technical effects: Contrary to the prior art's piecemeal printing technical route, the applicant proposes a technical solution capable of synchronous printing on the columnar surface. The present invention grows a layer of columnar material on the base column by keeping the photocurable liquid (also known as: printing ink) relatively fixed and only rotating the base column. This synchronous printing not only helps to improve the strength and uniformity of the formed columnar material, but also can effectively improve the printing efficiency.

[0029] Specifically, based on the comprehensive division of typical parameters such as thickness, height, and time sequence, the present invention proposes a method of dividing a complex columnar material (especially a columnar object involving a multi-layer structure) into multiple projection images (i.e., slice images) that conform to the shape of the base column and the projection rules, so that a layer structure can be synchronously and continuously generated on it by means of the rotation of the base column (specifically, the columnar material can be synchronously generated in the axial direction of the base column and continuously grown in the radial direction).

[0030] Furthermore, the applicant has noticed that printing parameters (such as factors like printing time and light intensity) also have a significant impact on the growth of columnar materials and the final forming quality. For different types of customized columnar materials, the printing parameters need to be adaptively adjusted. Thus, when facing large-scale production of columnar materials, or whenever new customized columnar materials need to be prepared, the problem of parameter selection will arise, and this parameter selection process will also extend the preparation cycle of columnar materials.

[0031] To reduce the workload in the parameter selection process, the present invention proposes a method for quickly screening out recommended fitting parameters. Specifically, the present invention constructs a printing prediction model by comprehensively selecting device parameters such as light intensity and time, as well as product parameters such as diameter. Among them, the product parameters can be independently set by the user in combination with customized standards. Then, through the set product parameters and fitting coefficients, the relative relationship between printing light intensity and time can be predicted and derived, thereby assisting the user to quickly set the light intensity or time that meets the conditions.

[0032] Furthermore, the present invention selects product parameters - thickness and the characteristics of the printing liquid (such as adsorption performance or initiator concentration) as key matching factors to comprehensively select historical printing data that meets the current printing conditions through product parameters and liquid characteristics, and directly combines the historical printing data to predict the corresponding fitting coefficients through the printing prediction model. Finally, the user can first set the printing parameters through the predicted fitting coefficients. The prediction of fitting coefficients can reduce the test workload required by the user before formal printing.

[0033] Among them, by reasonably setting the printing light intensity and printing time (the printing time further limits the rotation speed of the base column), it is ensured that under appropriate printing time, the liquid can be evenly coated on the surface of the base column, and at the same time, the liquid will not be separated due to too fast rotation speed. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for the description of the embodiments or the prior art. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, the elements or parts do not necessarily draw according to the actual scale. Obviously, the following described drawings are some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0035] Figure 1 It is a perspective schematic diagram of a printing device in an exemplary embodiment of the present invention;

[0036] Figure 2Schematic structural diagram of a printing device in an exemplary embodiment of the present invention;

[0037] Figure 3 Top view of a printing device in an exemplary embodiment of the present invention;

[0038] Figure 4 Schematic structural diagram of a groove of a printing device in an exemplary embodiment of the present invention;

[0039] Figure 5 Schematic structural diagram of a printing device in an exemplary embodiment of the present invention;

[0040] Figure 6 Schematic structural diagram of a printing device in another exemplary embodiment of the present invention;

[0041] Figure 7 Schematic structural diagram of an intermediate mechanism of a columnar material preparation device in another exemplary embodiment of the present invention;

[0042] Figure 8 Schematic structural diagram of a columnar material preparation device in another exemplary embodiment of the present invention;

[0043] Figure 9 Schematic partial structural diagram of a columnar material preparation device in another exemplary embodiment of the present invention;

[0044] Figure 10 Schematic step - flow diagram of a printing method in an exemplary embodiment of the present invention;

[0045] Figure 11a Schematic flow diagram of slicing and cutting a three - dimensional digital model in an exemplary embodiment of the present invention;

[0046] Figure 11b Schematic structural diagram of a three - dimensional digital model in another exemplary embodiment of an exemplary embodiment of the present invention;

[0047] Figure 11c For Figure 11b Schematic diagram of the cutting and combining process of the second sliced image of the sliced layer shown;

[0048] Figure 12 Schematic method - flow diagram in some other embodiments of the present invention;

[0049] Figure 13 Schematic diagram of a physical photo prepared based on the printing method shown in the present invention.

[0050] Reference numerals: first base 1, first driving mechanism 2, first bracket 3, second bracket 4, second base 5, first clamping head 6, first supporting portion 7, groove 71, supporting end 7a, liquid supply end 7b, reinforcing member 73, bridge-shaped bracket 8, second clamping head 9; moving mechanism 10, connecting plate 101, second driving mechanism 102, control module 11, heating mechanism 12, heating element 121, temperature controller 122, projection mechanism 13; three-dimensional digital model 01, spreading model 02, first sliced image A021, first sliced image B022, second sliced image 03. Detailed implementation

[0051] To make the objectives, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are some, but not all, of the embodiments of the present invention. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0052] In this article, suffixes such as "module", "component" or "unit" used to represent elements are only for the convenience of explaining the present invention, and they have no specific meaning in themselves. Therefore, "module", "component" or "unit" can be used interchangeably. In this article, the orientation or positional relationship indicated by terms such as "upper", "lower", "inner", "outer", "front", "rear", "one end", "the other end", etc. is based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be construed as a limitation of the present invention. In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance. In this article, unless otherwise clearly defined and limited, terms such as "installed", "provided with", "connected", etc. shall be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, a direct connection, or an indirect connection through an intermediate medium, and can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0053] As used herein, "and / or" includes any and all combinations of one or more of the listed related items. As used herein, "a plurality" means two or more, i.e., it includes two, three, four, five, etc. As used in this specification, the term "about" typically means + / - 5% of the stated value, more typically + / - 4% of the stated value, more typically + / - 3% of the stated value, more typically + / - 2% of the stated value, even more typically + / - 1% of the stated value, and even more typically + / - 0.5% of the stated value. In this specification, certain embodiments may be disclosed in a format that is within a certain range. It should be understood that this description of "within a certain range" is merely for convenience and brevity and should not be construed as a rigid limitation on the disclosed range. Therefore, the description of the range should be considered to have specifically disclosed all possible sub-ranges and individual numerical values within that range. For example, the description of the range 1 - 6 should be considered to have specifically disclosed sub-ranges such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6, etc., and the individual numbers within this range, such as 1, 2, 3, 4, 5, and 6. The above rules apply regardless of the breadth of the range.

[0054] In the prior art, a segmented printing technical route is adopted, that is, the extrusion head (for extruding printing ink) moves axially along the forming axis so that the printing ink is successively formed section by section in the axial direction of the forming axis (in other words, the solution adopted in the prior art is segmented printing in the length direction). However, the applicant has found that the strength and uniformity of the nerve conduit prepared based on this segmented printing technical route are poor, and since the extrusion head needs to continuously move from one end of the forming axis to the other end to complete the printing of one layer of the nerve conduit, the printing time is long and the efficiency is low.

[0055] Different from the existing technical route of segmented printing in the length direction, see Figures 1 - 10 , the present invention proposes a technical solution capable of synchronous printing. Specifically, the present invention fixes the photocurable liquid (also known as: printing ink) and only rotates the base column to grow a layer of columnar material on the base column. This synchronous printing not only helps to improve the strength and uniformity of the formed columnar material, but also can effectively improve the printing efficiency.

[0056] As Figure 11b shown, the "width (W)" of the image refers to its length in the axial direction of the base column. The "height (H)" of the image refers to the direction perpendicular or approximately perpendicular to the width. In order to explain the continuous preparation scheme of the columnar material of the present invention, the following takes Figure 11a as an example to describe the slicing process exemplarily: Figure 11aA columnar three-dimensional digital model 01 is provided. The three-dimensional digital model 01 is spread to obtain a spread model 02. The spread model 02 is sliced into multiple slices along its thickness direction to obtain a set of slice results. Correspondingly, according to the slice results (such as slice A with a rectangular pattern or slice B with a triangular pattern), a first slice image A021 and a first slice image B022 are generated respectively. Among them, the first slice image completely depicts the pattern information in the corresponding slice.

[0057] Further, for the first slice image, it will also be sequentially cut into multiple second slice images 03 along its width direction (as Figure 11a shown), and the multiple second slice images 03 will be associated with corresponding projection orders (specifically, it can be a sequential projection order, such as the first one, the second one...; or the projection order can also be set as a set projection time); thus, when the base column rotates one week, the optical machine will project the multiple second slice images 03 under one slice onto the base column in sequence, and cause the patterns in the slice to grow correspondingly on the base column.

[0058] In summary, based on the comprehensive division of thickness, height, and time sequence, the present invention provides a printing technology capable of continuously printing columnar materials. See Figures 10 - 12 shown, the present invention provides a preparation method for columnar materials, and the method includes:

[0059] S001, obtaining the three-dimensional digital model of the columnar material;

[0060] S002, performing layered slicing processing on the three-dimensional digital model along the thickness direction to obtain multiple slices correspondingly;

[0061] S003, obtaining a first slice image adapted to the preparation device of the columnar material according to the slice; wherein, the preparation device includes: a base column, and the base column is set to be able to rotate around its axial direction, the base column has a diameter and a working length, and the outer surface of the base column can adsorb a light-curing liquid layer with a certain thickness; an optical machine for projecting a digital light beam onto the outer surface of the base column, and the area where the digital light beam effectively covers the base column is the projection working area; correspondingly, the first slice image is the pattern corresponding to the spread slice, and the height of the first slice image matches the circumference of the base column, and the width of the first slice image is adapted to the working length;

[0062] S004, using a set segmentation method to segment and obtain multiple second slice images along the width direction of the first slice image, and the set segmentation method requires that the height of the second slice image matches the height of the projection working area, and the second slice image is associated with a corresponding projection order;

[0063] S005, the base column rotates at a set rotation speed so that the second slice images are projected onto the outer surface of the base column in sequence according to the projection order, enabling the photocuring liquid to be formed in sequence according to the patterns on the second slice images under the projection of the digital light beam. That is, corresponding 3D columnar materials are prepared by projecting the digital light beam onto the base column.

[0064] In some embodiments, the number of pixel rows of the first slice image satisfies a set slicing rule, and the slicing rule includes:

[0065] ; ; ; ; ;

[0066] wherein, n max is the maximum number of pixel rows of the first slice image in the height direction, N H , Nw are respectively the maximum number of pixels of the projection working area of the digital light beam in the height direction and the width direction; H p 、W p Minute are respectively the height and width of the projection working area of the digital light beam; l is the working length, h p is the circumference of the base column, d is the diameter.

[0067] In this embodiment, it is preferably ensured that the first slice image just covers and fits on the outer surface of the base column so that after the projection of the first slice image is completed, the structure corresponding to the slice layer can be generated on the base column.

[0068] In some embodiments, the thickness of one layer of the slice is , correspondingly, the pixel height of the first layer of the first slice image projected on the base column is ; the maximum pixel height of the th layer of the first slice image is .

[0069] In this embodiment, it is preferably ensured that the thickness of each layer of the slice is relatively uniform to ensure that the doses of the photocuring liquid of each layer of the slice are close to each other, so that the finally formed 3D columnar material has good uniformity.

[0070] In some embodiments, the first slice image is a grayscale image or a binary image. Correspondingly, S004 includes: sequentially extracting the lines formed by the pixel points in each row of the first slice image as subsets, where the black pixel points are recognized as the background of the second slice image, and the non-black pixel points are recognized as the pattern of the second slice image; creating a plurality of second slice images based on the black pixel points and the non-black pixel points respectively.

[0071] In some embodiments, the total number of the second slice images formed by the plurality of slices is:

[0072] ;

[0073] m is the number of the slices, is the thickness of one layer of the slices, n total is the total number of the second slice images of the three-dimensional digital model, n i is the i total number of the second slice images of the

[0074] Specifically, along the rotation direction of the column base, the lines formed by the pixel points in each row of the first slice image (grayscale image or binary image) of each layer are sequentially extracted as subsets (the black pixel points correspond to the background of the projection screen, and the non-black pixel points are the actual exposure pixel points, as shown in Figure 11a ) and copied to the center of the black background screen (the pixel ratio and quantity of the background screen are equivalent to those of the projection screen) as the line sequence corresponding to each layer of slices. The number of the line pattern sequences obtained after processing each layer of slices is (i.e., the total number of the second slice images generated by one layer of slices).

[0075] In some embodiments, it further includes steps: S006, monitoring the photocuring efficiency of the photocuring liquid; S007, when the photocuring efficiency is less than the set photocuring efficiency, correcting the second slice image and the projection time delay, where the projection time delay refers to the time that a single second slice image stays on the base column; the steps of correcting the second slice image and the projection time delay include:

[0076] merging at least two second slice images of the slices of the layer to be corrected to obtain a corrected slice image; where the layer to be corrected is the i layer, and correspondingly the height of the corrected slice image is ;

[0077] determining the projection time delay according to the corrected slice image, and the projection time delay is: ,n i For the i total number of corrected slice images of the slices of the layer to be corrected in the is the rotational speed.

[0078] In this embodiment, a correction mechanism for correcting the cutting result is also proposed. By comprehensively correcting the height and projection time delay of the second slice image, the strength and uniformity of the columnar material can be further improved.

[0079] For example, in some embodiments, as shown in Figure 11c , two adjacent line patterns (equivalent to the second slice image with a height H of only 1 pixel) can be appropriately merged into thickened lines with a pixel width of 2, 3,..., ( ), etc. That is, it is assumed that each layer is merged according to the same line width (i.e., the height of the second slice image), but the line merging widths of different layers are allowed to be different. Correspondingly, the number of patterns formed after correction of this layer is: .

[0080] And, as shown in Figure 13 , through printing tests, the printing scheme proposed by the present invention can still maintain good printing quality when preparing complex columnar materials. As can be seen from Figure 13 , the columnar material has a smooth surface and a clear shape. Specifically, Figure 13 the main components of the photocuring raw material used in

[0081] In some embodiments, S005 further includes the step of selecting the printing conditions of the three-dimensional digital model according to the fitting model; wherein, the printing conditions include: the thickness of the slice, the printing time of one layer of the slice, the light intensity, and the diameter of the base column; the fitting model includes: ; wherein, is the thickness, is the fitting coefficient, is the printing time, is the light intensity, is the diameter.

[0082] In order to more clearly illustrate the technical solution adopted by the present invention, the following will explain several exemplary preparation devices provided by the present invention through Figures 1 - 9 shown: Specifically, the present invention provides a preparation device for columnar materials (or a rotary printing device), including:

[0083] A base column, the base column having a diameter and a length, and the base column having a curved outer surface;

[0084] A sample addition element, the sample addition element being capable of accommodating a photocurable liquid; wherein, the sample addition element has a sample addition pool for accommodating the photocurable liquid, and the base column is arranged such that the outer surface can be at least partially immersed in the photocurable liquid; preferably, baffles can be provided at both ends of the sample addition pool so that an accommodation cavity is formed between the inner wall of the sample addition pool and the baffles, so that a certain dose of photocurable liquid can be accommodated therein; or, the sample addition element has at least one nozzle, and the nozzle can spray the photocurable liquid onto the outer surface so that a layer of photocurable liquid can be evenly adsorbed on the base column;

[0085] A support element, the support element being used to support the base column and capable of driving the base column to rotate around its axis at a set speed, and during the rotation of the base column, the outer surface can adsorb and form a photocurable liquid layer with a certain thickness;

[0086] An optical machine for projecting a digital light beam onto the surface of the base column; there is a first distance between the projection end of the optical machine and the surface of the base column at the initial printing moment;

[0087] A moving element, the moving element being used to drive the base column to move along the projection direction; wherein, when a structural layer with a first thickness grows on the base column, the moving element can drive the base column to move so that the distance between the projection end and the outer surface remains or is approximately the first distance.

[0088] For example, the moving element can move up and down in the vertical direction to adjust the size of the area where the base column is immersed in the photocurable liquid.

[0089] See Figure 1As shown, a specific configuration of the preparation device is as follows: The support element may include: a first base 1, on which a first driving mechanism 2 is arranged; a first support 3 arranged on the first base 1; a first clamping head 6, the first clamping head 6 is arranged on the first support 3 to be fixed by the first support 3, and a first end of the first clamping head 6 is connected to an output end of the first driving mechanism 2, and a second end of the first clamping head 6 is used to fix a first end of the base column; the base column has a columnar outer surface, and the columnar outer surface is used to provide a forming platform for the photocuring liquid (or raw material, printing ink, bio-ink, etc.) to guide the photocuring liquid to grow columnar materials (preferably nerve conduits) on the base column; the support element may further include: a second support 4, a second clamping head 9, the second clamping head 9 is arranged on the second support 4, and the second clamping head 9 is used to fix a second end of the base column; the sample adding element may include: a second base 5, on the second base 5, a first support portion 7 is arranged, an upper end of the first support portion 7 is provided with a groove 71 (equivalent to a sample adding pool) adapted to the shape of the base column, the groove is used to hold the liquid, and the first support portion is preferably made of a flexible material; the moving element may include: a moving mechanism 10, the moving mechanism 10 is used to drive the base column to reciprocate in the height direction; the moving mechanism includes: a connecting plate 101, the connecting plate 101 is connected to the second base 5; a second driving mechanism 102, the second driving mechanism 102 is connected to the second base to drive the second base 5 to move in the height direction; the preparation device may further include: a heating device, such as a heating mechanism 12, the heating mechanism is used to heat the liquid.

[0090] In some embodiments, the first and second clamping heads may be arranged on the same base. In some embodiments, the cross-sectional structure of the groove is semi-circular. In some embodiments, refer to Figure 7 As shown, the heating mechanism includes: a heating element 121 with a certain length, the heating element 121 is arranged at a lower end of the first support portion 7; a temperature controller 122 (refer to Figure 9 as shown), the temperature controller 122 is used to control the heating temperature of the heating element. Moreover, arranging the heating element with a certain length can on the one hand meet the requirement of uniform heating of the liquid, and on the other hand can support the flexible material. This dual function can further control the overall weight of the intermediate mechanism to reduce the moving load of the moving mechanism.

[0091] The process of completing multi-layer printing using the printing device in this embodiment is as follows:

[0092] The first support part is positioned at the first height, and at this time, the base column can be partially immersed in the liquid in the groove; the base column is controlled to rotate one week so that a layer of nerve conduit grows on the base column; the first support part is raised by a second height so that the base column can continue to be partially immersed in the liquid in the groove; the base column is controlled to rotate one week again so that a second layer of nerve conduit grows on the base column; repeating this cycle multiple times can quickly grow multiple layers of nerve conduits on the base column.

[0093] For example, the moving distance in the height direction (and the distance has two directions, positive or negative) is input in the control module 11 (such as a computer connected to the second driving mechanism). Positive represents the rising distance (mm) of the base column, and negative represents the falling distance (mm) of the base column. The second driving mechanism will drive the movement of the intermediate mechanism to change the height of the groove, realizing customizable coating of single or multiple layers of different materials on the base column.

[0094] That is to say, in this embodiment, by keeping the height of the base column relatively fixed and only moving the lightweight first support part, customizable multi-layer printing of columnar materials can be completed. Among them, the surface of the first support part made of flexible material also has flexible characteristics, so that when the base column accidentally touches its surface, its surface will not damage the materials that have grown on the base column. At the same time, the lighter flexible material can also reduce the load of the moving mechanism 10. And the heating element 121 is preferably arranged at the bottom end of the first support part, which can not only uniformly heat the liquid in the first support part as a whole, but also support the flexible first support part to avoid the problem of downward depression in the middle area of the first support part (that is, it can maintain the stable contact between the liquid and the base column).

[0095] From another perspective, the present invention adopts multiple technical means such as directly arranging liquid raw materials along the length direction of the base column, the first support part for supplying liquid made of flexible material, and the heating element arranged at the lower end of the first support part along the length direction to cooperate with each other, and as a whole provides a mobile system with safety (avoiding damage to the grown materials) and lightness. Therefore, when growing and preparing multiple layers of nerve conduits, on the one hand, this mobile system can reduce the control difficulty of the moving displacement accuracy through the lightweight intermediate mechanism, and at the same time, the flexible characteristics of the groove can reduce the damage to the existing nerve conduits on the base column during the contact process when the base column has accidental errors such as moving deviations.

[0096] Moreover, the liquid surface supply method adopted by this mobile system enables the liquid to uniformly contact each position of the base column at the same moment, which is beneficial to improving the uniformity of the formed columnar material and greatly reducing the growth time of the columnar material.

[0097] In other words, the present invention provides a method for preparing a columnar material by synchronously printing (or, overall printing, one-piece forming) a structural layer.

[0098] In some embodiments, it further includes: a projection mechanism 13, and the projection mechanism includes: an optical projector (which can also be referred to as an optical engine), and the optical projector is arranged above the base column for providing an optical projection to the base column. For example, in some embodiments, the optical projector can be a projector based on CAL (Computed Axial Lithography). In some embodiments, the optical projector can also adopt a combined system with a 405nm laser, a scanning field lens, and an xy scanning galvanometer. Again, for example, the optical projector can also be an optical engine based on DLP (i.e., Digital Light Processing), or an SLM (Selective laser melting) optical engine. In some embodiments, the raw material can be a photocurable solution.

[0099] In some embodiments, referring to Figure 7 as shown, the first support portion 7 includes: a liquid supply end 7b, and the groove is arranged on the liquid supply end; both sides of the liquid supply end 7b are respectively connected to the second base through support ends 7a; wherein, the height of the upper end surface of the support end 7a is lower than the height of the lateral opening of the groove, so as to leave a certain operation space between the base column, the lateral opening, and the upper end surface of the support end 7a outside both ends of the groove, so that the user can supplement liquid into the groove through the lateral operation space.

[0100] Especially during the printing process, supplementing liquid from the side can avoid affecting the nerve conduit already formed on the base column.

[0101] Furthermore, in some embodiments, the heating element 121 can be a plate with a certain length (such as a rectangular plate, on which heating elements are arranged, such as heating wires, etc.), and its length is the same as or close to the length of the liquid supply end, so that the heating element 121 is arranged at the lower end of the liquid supply end 7b to uniformly heat the liquid at its upper end.

[0102] Or, in some embodiments, the heating element can be a column with a certain length, on which heating elements such as heating wires are arranged.

[0103] In some embodiments, at least a part of the first support portion is made of a flexible material. For example, in some embodiments, at least the liquid supply end is made of a flexible material. For example, in some embodiments, at least the surface of the groove in the liquid supply end is made of a flexible material. In some embodiments, a heating plate may also be provided on the side of the first support portion to heat the liquid in the first support portion and support the first support portion. In some embodiments, the flexible material refers to a polymer material with a certain bending plasticity. For example, it can be a flexible plastic material, a flexible nano material, a flexible electronic material, a flexible capsule material, etc.

[0104] Flexible materials generally have the following characteristics: High elasticity: able to withstand large deformations without permanent damage. Softness: the material feels soft and is easy to bend and fold. Plasticity: can change shape by heating, pressure, etc. and maintain the new shape after cooling or pressure release. Durability: can still maintain performance after repeated deformations. Adaptability: able to adapt to different environmental conditions and usage requirements. For example, the flexible materials selected in the present invention can be one or more of the following: Rubber: natural rubber and synthetic rubber; Silicone: has good high temperature resistance, low temperature resistance and biocompatibility; Polyurethane; Polyvinyl chloride (PVC).

[0105] In some embodiments, the hardness range of the flexible material is 60A - 90A.

[0106] Preferably, in some embodiments, when the number of layers of columnar materials is relatively small, a rotary printing device as shown in Figures 1 - 6 can be used. The rotary printing device includes:

[0107] A first base 1, on which a first driving mechanism 2 is provided, such as a motor;

[0108] A first bracket 3; and a first clamping head 6, the first clamping head 6 is arranged on the first bracket 3 to be fixed by the first bracket 3, and the first end of the first clamping head 6 is connected to the output end of the first driving mechanism 2, and the second end of the first clamping head 6 is used to fix / lead out the base column (or rather, the first clamping head is used to fix the first end of the base column); the base column has a columnar surface, and the columnar surface is used to provide a forming platform for the liquid;

[0109] A second bracket 4, and a second clamping head 9, the second clamping head 9 is arranged on the second bracket 4, and the second clamping head 9 is used to fix the second end of the base column;

[0110] A second base 5, a first support portion 7 is provided on the second base 5, and a groove 71 adapted to the shape of the base column is provided on the first support portion 7.

[0111] For example, in some embodiments, the cross-sectional structure of the groove is semi-circular.

[0112] In some embodiments, the first support portion is preferably made of a flexible material. Correspondingly, the intermediate mechanism further includes: a second support portion for supporting the first support portion.

[0113] For example, in some embodiments, refer to Figures 1 - 2 As shown, the second support portion is a bridge-shaped bracket 8 disposed below the first support portion, and the bridge-shaped bracket 8 is disposed in a direction perpendicular to or intersecting the axial direction of the first support portion.

[0114] Again, for example, in some embodiments, refer to Figure 6 As shown, the second support portion may also be a reinforcing member 73 disposed on the lower sides of both ends of the first support portion 7, and the two reinforcing members 73 are connected to form an arched area on the lower side of the first support portion 7 (or, it is arranged as an "arch bridge shape").

[0115] Preferably, in some embodiments, the shape or size of the liquid tank can be flexibly set according to the preparation requirements of the columnar material. Taking the nerve conduit as an example, customized according to clinical needs, the height, weight, age, gender, and injury site of different patients will affect the thickness and length of the nerve, so it needs to be measured and customized each time. Therefore, the diameter range of the liquid tank can be designed according to the inner diameter of the nerve and the thickness of the catheter, and the catheter thickness can be determined by comprehensively considering mechanics and degradation.

[0116] Preferably, the diameter of the base column is customized according to clinical needs, and it is required to be made of stainless steel material, having electrical conductivity, straight and rigid, smooth tube wall, etc.

[0117] Preferably, the surface of the groove 71 is made of an elastic material, which can reduce the friction of the contact surface. The present invention preferably uses TPU material, with a hardness range of 60~90A and a printing temperature of 195~205°C. This groove setting has the advantages of wear resistance, corrosion resistance, strong elasticity, and low production cost. Through the "arch bridge" structure designed by the present invention, while strengthening the base, the advantages of the TPU material can be maintained.

[0118] The following explains the working process of the above printing device with an exemplary printing process (the pictures in this embodiment are equivalent to the above-mentioned second slice images):

[0119] First, design the structural layer (such as the slice layer) to be formed by the base column rotating one week (360°) and the corresponding picture sequence (or directly create a sequence without a model). The sequence contains n pictures. If the rotational speed of the column is v (° / s), then the projection time t of a single projection picture on the column s = 360 / (n×v) (s).

[0120] Next, an appropriate amount of photocurable liquid is evenly adsorbed on the outer surface of the base column. At the same time, for the composite printing material, heat treatment can also be performed to maintain the activity of the composite printing material.

[0121] After a period of uniform rotation and exposure with a constant light intensity (for example, the time for one rotation is set as T), the thickness of the structural layer formed on the outer layer of the column with a diameter of d after rotational exposure is related to the total projection time T (s) and the light intensity I (mW / cm²). For the case where a single light machine exposes one layer of the column and the column itself is opaque, only one side is irradiated at any moment, so the final received dose is approximately Δ = 1 / 2 × T × I. Since the layer thickness is usually relatively thin, it is in the millimeter range.

[0122] The applicant comprehensively considers the attenuation of light before and after curing of the above materials and believes that there is approximately a relationship between the cross-sectional area (regarded as a ring) S of the formed outer layer and the dose Δ:

[0123] 。

[0124] Furthermore, in order to reduce the preparation workload and quickly complete the printing preparation of new products (such as columnar materials with different raw materials or different sizes), the present invention also provides a preparation method applicable to the above rotational printing equipment as follows:

[0125] S100 Provide a columnar material preparation device for printing columnar materials. The columnar material preparation device includes: a base column for guiding the growth of the columnar material on it, the base column having a diameter; at least one light machine (or projector) arranged facing the base column;

[0126] S101 Obtain printing condition data. The printing condition data includes first type data; the first type data includes one or more of the following: thickness, adsorption performance (i.e., adsorptivity), initiator concentration;

[0127] Among them, the thickness refers to the thickness of the slice to be printed, the adsorption performance refers to the adsorption ability of the base column to the liquid (or ink), and the initiator concentration is the concentration of the initiator in the liquid;

[0128] For example, in some embodiments, when a new nerve conduit product needs to be printed, the user can comprehensively determine the current printing parameters (such as printing time, light intensity, or applicable base column) in combination with the customization requirements of the nerve conduit (i.e., thickness) and the characteristics of the existing raw materials (i.e., adsorption performance, initiator concentration).

[0129] S102 queries the matching historical printing data from the historical database according to the printing condition data. The historical database includes multiple groups of the historical printing data. One group of the historical printing data includes: the first type of data and the second type of data. The second type of data includes: time (i.e., the time required for the base column to rotate one circle), light intensity (i.e., the light intensity of the projector), and diameter (i.e., the diameter of the base column).

[0130] For example, in some embodiments, whenever a neural catheter is printed, the relevant data during the printing process will be collected to obtain a group of historical printing data.

[0131] For example, in some embodiments, continuously collecting the relevant data during the printing process can continuously update the historical database to improve the reference application value of the historical database.

[0132] Among them, S102 includes the steps of: querying at least one group of the corresponding historical printing data from the historical database according to the first query rule; the first query rule requires that the printing condition data and at least two items of the first type of data in the historical printing data conform to a preset matching rule, and the matching rule requires that the difference between the corresponding two numerical values belongs to the corresponding set first threshold range.

[0133] For example, in some embodiments, when the difference between the thickness in the printing condition data and the thickness in the historical printing data belongs to the first sub-range, it is considered that the two match; for example, in some embodiments, when the difference between the adsorption performance in the printing condition data and the adsorption performance in the historical printing data belongs to the second sub-range, it is considered that the two match. For example, in some embodiments, when the difference between the initiator concentration in the printing condition data and the initiator concentration in the historical printing data belongs to the third sub-range, it is considered that the two match.

[0134] Preferably, in some embodiments, when the difference between the corresponding two numerical values belongs to the corresponding set first threshold range, the two numerical values refer to thickness and adsorption performance, or the two numerical values refer to thickness and initiator concentration.

[0135] S103 predicts the corresponding fitting coefficient by using at least one group of the queried historical printing data through a set printing prediction model (or a fitting model); the printing prediction model is:

[0136] ; where is the thickness, is the fitting coefficient, is the time, is the light intensity, is the diameter;

[0137] For example, in some embodiments, multiple fitting coefficients can be selected from multiple sets of historical printing data, and the finally predicted fitting coefficient can be the average of the multiple fitting coefficients.

[0138] Again, for example, in some embodiments, multiple sets of historical printing data can be fitted by means of function fitting to determine the value of the final fitting coefficient through the fitting function.

[0139] S104 uses the printing condition data and the fitting coefficient to predict, through the printing prediction model, the second type of data that conforms to the current printing condition data.

[0140] The applicant notes that printing parameters (such as factors like printing time, light intensity, etc.) can have a great impact on the growth of the nerve conduit and the final forming quality, and for different types of customized nerve conduits, the printing parameters need to be adjusted adaptively. Thus, when facing large-scale production of nerve conduits, or rather, whenever a new customized nerve conduit needs to be prepared, the problem of parameter selection will be faced, and this parameter selection process will also extend the preparation cycle of the nerve conduit.

[0141] In order to reduce the workload in the parameter selection process, the present invention proposes a method for quickly screening out recommended fitting parameters. Specifically, the present invention constructs a printing prediction model by comprehensively selecting device parameters such as light intensity and time and product parameters such as diameter. Among them, the product parameters can be independently set by the user in combination with customized standards. Furthermore, the relative relationship between the printing light intensity and time can be predicted and derived by combining the set product parameters with the fitting coefficient, thereby assisting the user to quickly set the light intensity or time that meets the conditions.

[0142] Furthermore, the present invention selects product parameters - thickness, characteristics of the printing liquid (such as adsorption performance or initiator concentration) as key matching factors to comprehensively select historical printing data that conforms to the current printing conditions through the product parameters and liquid characteristics, and directly combines the historical printing data to predict the corresponding fitting coefficient through the printing prediction model. Finally, the user can first set the printing parameters through the predicted fitting coefficient. And the prediction of the fitting coefficient can reduce the test workload required by the user before formal printing. Among them, by reasonably setting the printing light intensity and printing time (the printing time further limits the rotation speed of the base column), it is ensured that the liquid can be evenly coated on the surface of the base column at an appropriate printing time, and at the same time, the liquid will not break away due to too fast rotation speed.

[0143] In some embodiments, it further includes steps: S105 performing at least one test using the second type of data predicted in S104; S106 recording the test printing data during the test, where the test printing data includes: the thickness, the time, the light intensity, the diameter; S107 obtaining the fitting coefficient by fitting through the printing prediction model according to the test printing data; S108 determining whether the difference between the fitting coefficient in S107 and the fitting coefficient in S103 belongs to a set second threshold range; if so, using the fitting coefficient in S107 and / or the fitting coefficient in S103 as the recommended fitting coefficient.

[0144] In this embodiment, before actual production (especially before mass production), the fitting coefficient selected can be comprehensively evaluated through at least one test printing result and the predicted fitting coefficient to re-verify the selected fitting coefficient. If the two results are similar, the recommended result is considered relatively reliable and suitable for promotion to formal production.

[0145] Furthermore, in some embodiments, the user can select a better fitting coefficient from the fitting coefficient in S107 and the fitting coefficient in S103 in combination with the actual comparison results and work experience. Therefore, the fitting coefficient recommendation method in this embodiment can reduce the number of tests required by the user during the process of exploring parameters to a certain extent and reduce the workload during the parameter wear process.

[0146] In some embodiments, the printing condition data further includes: time or light intensity.

[0147] The method for preparing columnar materials provided by the present invention is particularly suitable for printing columnar objects with multiple structural layers. Specifically, the preparation process is as follows: First, identify multiple structural layers of the columnar object; for each structural layer, create a corresponding printing model respectively, and cut out multiple pictures to be projected according to the printing model; rotate the base column so that the projector projects the pictures onto the base column at a set time and order to form a multi-layer columnar object with a specific pattern structure.

[0148] Embodiment 2

[0149] Correspondingly, the present invention also provides a columnar material preparation system (or a rotary printing system), including:

[0150] A printing condition acquisition module for acquiring printing condition data, where the printing condition data includes first type of data; the first type of data includes one or more of the following: thickness, adsorption performance, initiator concentration;

[0151] A query module, configured to query, from a historical database, historical print data that matches the print condition data through the print condition data. The historical database includes multiple groups of the historical print data. One group of the historical print data includes: the first type of data, and the second type of data. The second type of data includes: time, light intensity, and diameter. Wherein, the query module is configured to query, from the historical database, at least one group of corresponding historical print data by using a first query rule. The first query rule requires that the print condition data and at least two items of the first type of data in the historical print data conform to a preset matching rule. The matching rule requires that the difference between the corresponding two numerical values belongs to a corresponding set first threshold range.

[0152] A first prediction module, configured to predict a corresponding fitting coefficient by using at least one group of the queried historical print data through a set print prediction model. The print prediction model is:

[0153] ; Wherein, is the thickness, is the fitting coefficient, is the time, is the light intensity, is the diameter;

[0154] A second prediction module, configured to predict the second type of data that conforms to the current print condition data by using the print condition data and the fitting coefficient through the print prediction model.

[0155] Further, the system further includes:

[0156] A test input module, configured to record test print data during a test when at least one test is performed by using the second type of data predicted in the first prediction module. The test print data includes: the thickness, the time, the light intensity, and the diameter.

[0157] A second prediction module, configured to fit the fitting coefficient through the print prediction model according to the test print data.

[0158] A judgment module, configured to judge whether the difference between the fitting coefficient in the second prediction module and the fitting coefficient in the first prediction module belongs to a set second threshold range. If so, use the fitting coefficient in the second prediction module and / or the fitting coefficient in the first prediction module as the recommended fitting coefficient.

[0159] The rotary printing system in the present invention can implement the method steps in any of the above embodiments, which will not be elaborated here.

[0160] Further, in some embodiments, the first data type may further include one or more of the following: the number of pictures n to be projected by the projector when printing a layer of the nerve conduit: affecting the printing accuracy of the angular distribution of the column rotation; the resolution of the projector: affecting the printing accuracy of the axial distribution of the base columns; the material ratio of the liquid: such as the physicochemical properties of electrospinning, the gel material components (such as colorants, initiators); the base columns and grooves: the light transmittance, roughness, stiffness, toughness, etc. of the base columns, and the shape, depth, width, etc. of the grooves for filling materials.

[0161] It should be noted that the columnar object (or columnar material) prepared by the present invention refers to a columnar structure with a certain length, and the columnar structure can be solid or hollow. For example, according to different raw material types, various columnar objects such as nerve conduits, pipes (such as plastic pipes) can be prepared respectively.

[0162] It should be noted that in this text, the terms "include", "comprise" or any other variant thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "including a..." does not exclude the existence of additional identical elements in the process, method, article or device including that element. Through the description of the above embodiments, those skilled in the art can clearly understand that the above embodiment methods can be implemented by means of software plus a necessary general hardware platform, and of course also by hardware, but in many cases the former is a better implementation method. Based on such an understanding, the technical solution of the present invention, in essence, or the part that contributes to the prior art can be embodied in the form of a software product. The computer software product is stored in a storage medium (such as ROM / RAM, magnetic disk, optical disc) and includes several instructions for causing a computer terminal (which can be a mobile phone, computer, server, or network device, etc.) to execute the methods described in various embodiments of the present invention. The above has described the embodiments of the present invention in conjunction with the drawings, but the present invention is not limited to the above specific embodiments. The above specific embodiments are merely illustrative and not restrictive. Under the inspiration of the present invention, those of ordinary skill in the art can also make many forms without departing from the purpose of the present invention and the scope protected by the claims, and these all belong to the protection scope of the present invention.

Claims

1. A method for preparing a columnar material, characterized in that, The method includes: S001, obtaining a three-dimensional digital model of the columnar material; S002, performing layer slicing processing on the three-dimensional digital model in the thickness direction to correspondingly obtain multiple slices; S003, obtaining a first slice image adapted to the preparation device of the columnar material according to the slice; wherein, the preparation device includes: a base column, and the base column is arranged to be rotatable around its axial direction, the base column has a diameter and a working length, and the outer surface of the base column can adsorb a light-curing liquid layer with a certain thickness; a light machine for projecting a digital light beam onto the outer surface of the base column, and the area effectively covered by the digital light beam on the base column is the projection working area; correspondingly, the first slice image is the pattern corresponding to after the slice is spread, and the height of the first slice image matches the circumference of the base column, and the width of the first slice image is adapted to the working length; S004, using a set segmentation method to segment along the width direction of the first slice image to obtain multiple second slice images, and the set segmentation method requires that the height of the second slice image matches the height of the projection working area, and the second slice image is associated with a corresponding projection order; S005, the base column rotates at a set rotation speed so that the second slice images are sequentially projected onto the outer surface of the base column according to the projection order, so that the light-curing liquid is sequentially formed in accordance with the pattern on the second slice image under the projection of the corresponding digital light beam.

2. The preparation method of a columnar material according to claim 1, characterized in that The number of pixel rows of the first slice image satisfies a set slice rule, and the slice rule includes: ； ； ； ； ； Among them, n max is the maximum number of pixel rows of the first slice image in the height direction, N H , Nw are respectively the maximum number of pixels of the projection working area of the digital light beam in the height direction and the width direction; H p 、W p points are respectively the height and width of the projection working area of the digital light beam; l is the working length, h p is the perimeter of the base column, d is the base column diameter.

3. The preparation method of a columnar material according to claim 2, characterized in that, The thickness of one layer of the slice is , correspondingly, the pixel height of the first slice image projected on the base column for the first layer is ; the -th layer of the first slice image has a maximum pixel height of .

4. The preparation method of a columnar material according to claim 2, characterized in that The first slice image is a grayscale image or a binary image, and correspondingly, S004 includes: Sequentially extracting the lines composed of pixel points in each row of the first slice image as subsets, wherein the black pixel points are identified as the background of the second slice image, and the non-black pixel points are identified as the pattern of the second slice image; Creating multiple second slice images according to the black pixel points and the non-black pixel points respectively.

5. The preparation method of a columnar material according to claim 4, characterized in that, The total number of the second slice images formed by the multiple slices is: ； m is the number of said slices, is the thickness of one layer of said slices, n total is the total number of said second slice images of said three-dimensional digital model, n i is the i total number of said second slice images of the layer of said slices.

6. The preparation method of a columnar material according to claim 1, characterized in that, It further includes the step: S006, monitoring the light-curing efficiency of the light-curing liquid; S007, when the light-curing efficiency is less than the set light-curing efficiency, correcting the second slice image and the projection time delay, wherein the projection time delay refers to the time that a single second slice image stays on the base column, and the step of correcting the second slice image and the projection time delay includes: At least two of the second slice images of the slices of the layer to be corrected are merged to obtain a corrected slice image; wherein, the layer to be corrected is the i th layer, and correspondingly, the height of the corrected slice image is ; Determine the projection time delay according to the corrected slice image, where the projection time delay is: , n i is the total number of the corrected slice images of the slices of the i layer to be corrected, is the rotation speed.

7. The preparation method of a columnar material according to claim 5, characterized in that, S005 further includes the step: Select the printing conditions of the 3D digital model according to the fitting model; wherein, the printing conditions include: the thickness of the slice, the printing time of one slice, the light intensity, and the diameter of the base column; the fitting model includes: ; wherein, is the thickness, is the fitting coefficient, is the printing time, is the light intensity, is the base column diameter.

8. A preparation system for columnar materials, characterized in that, The system includes: A model acquisition module for obtaining a three-dimensional digital model of the columnar material; A slicing module for performing layer slicing processing on the three-dimensional digital model in the thickness direction to correspondingly obtain multiple slices; A first image acquisition module, configured to obtain a first slice image adapted to the preparation device of the columnar material according to the slice; wherein, the preparation device includes: a base column, and the base column is arranged to be rotatable about its axial direction, the base column has a diameter and a working length, and the outer surface of the base column can adsorb a certain thickness of photocurable liquid; an optical machine, configured to project a digital light beam onto the surface of the base column, and the area effectively covered by the digital light beam on the base column is the projection working area; correspondingly, the first slice image is the pattern corresponding to after the slice is spread, and the height of the first slice image matches the circumference of the base column, and the width of the first slice image is adapted to the working length; A second image acquisition module, configured to obtain a plurality of second slice images by segmenting along the width direction of the first slice image using a set segmentation method, the set segmentation method requires that the height of the second slice image matches the projection working area, and the second slice image is associated with a corresponding projection order; A printing module, configured to control the base column to rotate at a set rotation speed, so that the second slice images are sequentially projected onto the outer surface of the base column according to the projection order, so that the photocurable liquid is sequentially formed into a pattern on the second slice image under the projection of the corresponding digital light beam.

9. A method for preparing a columnar material according to any one of claims 1-7, characterized in that, And the base column has a curved outer surface; A sample adding element, the sample adding element can accommodate the photocurable liquid; Wherein, the sample adding element has a sample adding pool for accommodating the photocurable liquid, and the base column is arranged so that the outer surface can be at least partially immersed in the photocurable liquid; or, the sample adding element has at least one nozzle, and the nozzle can spray the photocurable liquid on the outer surface; A support element, the support element is used to support the base column, and can drive the base column to rotate around its axis at a set speed, and the base column can adsorb and form a layer of photocurable liquid with a certain thickness on the outer surface during rotation; An optical machine, configured to project a digital light beam onto the surface of the base column; there is a first distance between the projection end of the optical machine and the surface of the base column at the initial printing moment; A moving element, the moving element is used to drive the base column to move along the projection direction; wherein, when the base column grows a structural layer with a first thickness, the moving element can drive the base column to move so that the distance between the projection end and the outer surface remains or is approximately the first distance.

10. The preparation method of a columnar material according to any one of claims 9, characterized in that, The preparation device further includes: a heating device, the heating device is used to heat the base column and / or the sample adding pool; And / or, the preparation device further includes: a photography device, the photography device is used to collect the image information of the base column.

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