SPF-grade mouse rearing cage

Abstract

The invention relates to the technical field of medical experiment equipment, in particular to an SPF-level mouse rearing cage which comprises a supporting seat, a pipeline used for ventilation is arranged in the middle of the supporting seat, an opening is formed in the pipeline, a rotating seat used for placing a cage body is arranged on the pipeline, and the cage body is communicated with a deformable air tap. Connecting plates are arranged at the positions, close to the air nozzles, of the cage body in the vertical direction, the two ends, in the length direction, of the two connecting plates are rotationally connected with connecting ends through shaft bodies and torsional springs, the connecting ends are rotationally connected with reversing rods through rotating shafts and torsional springs, and the sections of the reversing rods are of a rectangular structure. A reversing rod is arranged in the cage body, the reversing rod is connected with the end, away from the cage body, of the air nozzle in a glued mode, a plurality of through holes used for the reversing rod to penetrate through are formed in the rotating base, the through holes are evenly formed at intervals, and a risk avoiding mechanism used for mice to avoid injuries is arranged in the cage body. By means of the mouse cage, hurt caused by mutual attack of laboratory mice in the cage body can be reduced.

Description

Technical Field

[0001] The invention belongs to the technical field of medical experimental equipment, and in particular relates to an SPF-grade mouse breeding cage. Background Art

[0002] The SPF-level experimental animal barrier system is a facility that provides a highly clean and controllable living environment for experimental animals. It plays a vital role in animal experiments and ensures the accuracy and reliability of experimental results. For experimental mice, a rotary feed cage and a side-sealed cage are usually used. The cage structure is shown in Chinese Patent 201120412289.X. It includes a sealed box body and a cage cover. The outer end face and the inner end face of the box body are respectively provided with an air inlet and an exhaust port, and the distribution position of the exhaust port is higher than the air inlet. The air inlet is arranged at the lower part of the outer end face of the box body, and the exhaust port is arranged at the upper part of the inner end face of the box body. It is particularly preferred that the orthographic projection of the box body on the horizontal plane is fan-shaped, and its inner end is smaller than the outer end.

[0003] The first inventor of this patent presided over (1) Henan Provincial Science and Technology Key Project (Project No. 242102310087, Project Name: The mechanism of Huatan Huoxue Jiedu Recipe's anti-atherosclerosis effect by regulating macrophage ferroptosis via SystemXc- / GSH / GPX4 axis); (2) Henan Provincial Medical Science and Technology Key Project (Project No. LHGJ20230690, Project Name: Based on the material basis of efficacy, the mechanism of Huatan Huoxue Jiedu Recipe's anti-atherosclerosis effect by inhibiting macrophage pyroptosis via MALAT1 / NLRP3 / 1L-1β signaling axis) which required a large number of experimental mice for modeling; (3) Henan Provincial Natural Science Foundation (Project No. 232300420273, Project Name: Based on the MALAT1 / miR-15b-5p / MAPK1 signaling axis, the mechanism of Huatan Huoxue Jiedu Recipe's anti-atherosclerosis effect by inhibiting macrophage pyroptosis was explored).

[0004] During the mouse breeding and modeling process, it was found that the existing mouse cages had the following deficiencies in actual use: ① The space is small and some experimental mice are naturally irritable and affected by experimental factors (such as high-fat diet), which will further aggravate the mice's irritability and easily cause mutual attacks, resulting in injuries or even death of mice, and the existing mouse cages lack emergency avoidance devices; ② Most drinking water devices are hanging gravity water bottles, which will drip due to gravity when not in use, making the cage environment humid, the bedding and mouse hair soaked, and the long-term damp living space can easily cause skin diseases or even death in mice; ③ At this stage, adding feed requires manual operation, which is relatively cumbersome, and some special feeds are prone to deterioration due to seasonal issues, affecting the progress of the experiment; ④ During the growth of mice, the incisors are always growing, and the grinding equipment needs to be put in regularly. At this stage, most of them are directly put in, and it is difficult to remove the residue as a consumable; ⑤ At this stage, the exhaust device only considers the inlet and outlet ventilation, and does not consider the impact of odor on experimental data. ⑥ Among the litter materials, wood chip litter contains fine dust that can easily cause lung damage to mice, or even lead to their death; corn cob litter, mice will eat corn cobs, which can easily cause intestinal obstruction, affect the accuracy of experimental data, or even cause death. Summary of the invention

[0005] In order to reduce the damage caused by mutual attack among experimental mice in a cage, the present invention provides an SPF grade mouse breeding cage.

[0006] The technical scheme is that an SPF-grade mouse breeding cage comprises a support seat, a pipe for ventilation is arranged in the middle of the support seat, an opening is arranged on the pipe, a rotating seat for placing the cage body is arranged on the pipe, a plurality of rotating seats are arranged evenly spaced along the length direction of the pipe, a deformable air nozzle is connected to the cage body, a connecting plate is arranged in the vertical direction near the air nozzle on the cage body, there are two connecting plates and they are symmetrically arranged about the air nozzle, both ends of the connecting plates in the length direction are connected to the torsion spring through the shaft body, and the connecting end is connected to the torsion spring through the rotating shaft. A reversing rod is connected to form a structure in which the reversing rod can swing horizontally and vertically under the action of the shaft and the rotating shaft and then move out of or into the opening. The cross-section of the reversing rod is a rectangular structure. The reversing rod is glued to the end of the air nozzle away from the cage body. A through hole for the reversing rod to pass through is provided on the rotating seat. There are multiple through holes and they are evenly spaced. A placement hole is provided on the cage body. A card ball is provided in the placement hole. An iron chain is provided at one end of the card ball. A teething rod is connected to one end of the iron chain. A risk avoidance mechanism for mice to avoid harm is provided in the cage body, and a feeding device for feeding is also included.

[0007] Preferably, the rotating seat includes a rotating plate along a horizontal plane and a rotating ring sleeved on the outside of the pipe, the rotating ring is rotatably connected to the pipe through a bearing, and the rotating plate is provided with convex strips, and there are multiple convex strips that are evenly spaced, forming a structure in which the convex strips divide the rotating plate into multiple mounting positions for placing the cage body, and the edge of each mounting position is provided with a guard strip, and an open groove is provided in the middle of the guard strip, forming a structure in which the cage body is pushed upward after one end of the clip is placed in the open groove.

[0008] Preferably, a sliding column with an integral structure is provided on one side of the cage body close to the rotating ring, and there are two sliding columns which are symmetrically arranged about the center line of the cage body. The sliding column includes a column body and a limiting ball connected to one end of the column body, and a sliding groove used in conjunction with the sliding column is provided on the rotating ring.

[0009] Preferably, a padding plate is provided between each cage body and the rotating seat, the padding plate is provided with a groove used in cooperation with the bottom surface of the cage body, and the padding plate comprises an upper padding layer for liquid leakage and a lower padding layer for absorbing water.

[0010] Preferably, the avoidance mechanism includes a main pipe detachably connected to the cage body, one end of the main pipe is connected to two branch pipes with the same structure and detachably connected to the cage body, a one-way door is provided at the end of the branch pipe away from the main pipe, a reversing door is provided between the main pipe and the branch pipe, the main pipe and the branch pipe have a side away from the bottom of the cage body made of transparent material and a side close to the bottom of the cage body made of non-transparent material, forming a structure in which the first mouse enters one branch pipe through the reversing door and the second mouse enters the other branch pipe through the reversing door.

[0011] Preferably, the feeding device includes a feeding mechanism and a displacement mechanism, and a control system electrically connected to the feeding mechanism and the displacement mechanism. The feeding mechanism includes a carrier frame, and the displacement mechanism is connected to the carrier frame to form a structure in which the carrier frame moves in a set direction under the action of the displacement mechanism and the control system. A material box is provided on the carrier frame, and a weighable material conveying mechanism is provided at the discharge port of the material box, and a discharge pipe is provided at one end of the material conveying mechanism. A feed trough is provided on the cage body, forming a structure in which the feeding structure moves the discharge pipe to the feed trough under the action of the displacement mechanism. A fixed rod is provided on the side of the support seat away from the displacement mechanism, and a motor is provided on the fixed rod. The motor and the rotating seat are arranged in a one-to-one correspondence, and a gear ring is provided on the rotating seat around it, and a gear meshing with the gear ring is provided on the motor. The motor is electrically connected to the power supply through the control system, forming a structure in which the motor drives the rotating seat to rotate according to the set time under the action of the control system when feeding the mouse.

[0012] Preferably, a diode cold patch is provided on the outer wall of the material box, and a receiving barrel is provided on the outer wall of the material box. A liquid outlet and a water pipe are provided on the receiving barrel, forming a structure for removing condensed water through the liquid outlet and the water pipe.

[0013] Preferably, the feed trough includes a folding net, which is in an isosceles trapezoidal shape, and a movable door is hingedly connected to the short shaft through a torsion spring on the cage body, and a claw for cleaning waste is provided on the cage body near the feed trough, and push blocks are provided on the opposite sides of the discharge pipe, forming a structure in which the discharge pipe moves along the feed trough and pushes the claw and the movable door to rotate to clean the waste, and the discharge pipe is discharged under the action of the control system after it retracts a set distance.

[0014] Preferably, the support frame is provided with a waste recovery mechanism which is arranged in parallel with the material conveying mechanism and can be weighed, and the support frame is provided with a waste box for recovering waste.

[0015] The beneficial effect of the present invention is that a risk avoidance mechanism is arranged in the cage, the risk avoidance mechanism includes a main pipe and a branch pipe, and a reversing door is arranged at the position where the branch pipe is connected to the main pipe, so that after the first experimental mouse enters the second branch pipe, the second experimental mouse can only enter the other branch pipe, so that the fighting experimental mice are separated, and the damage caused by mutual attack of the experimental mice is reduced; The feeding mechanism includes a feeding mechanism, a displacement mechanism and a control system. The feed box is used to store feed. The diode cold patch is set to reduce the deterioration of feed. The receiving bucket, liquid outlet and water pipe are set to ensure the discharge of condensed water on the feed box. The material conveying mechanism realizes the delivery of feed to the feed trough through the discharge pipe under the action of the control system and the displacement mechanism. The setting of the claw on one side of the feed trough is coordinated with the setting of the isosceles trapezoidal structure at the bottom of the feed trough. Under the action of the movable door, the push block on the discharge pipe pushes the claw and the movable door to realize the discharge of waste materials. The waste materials are stored under the action of the weighable waste recovery mechanism and the waste box. The control system can record and judge the actual food intake of the experimental mice according to the weighing data of the material conveying mechanism and the waste recovery mechanism. The displacement mechanism drives the discharging pipe to move in the vertical and horizontal directions. The rotating seat of the cage body is rotated by the motor on the fixed rod. The gear ring on the rotating plate is meshed with the gear on the motor. Under the action of the control system, the rotating seat is rotated according to the set angle to realize the automation of feeding. One end of the cage body is slidably connected with the rotating ring through a sliding column and a sliding groove, so that the clip is placed between the rotating plate and the cage body through the opening groove to realize the movement of the cage body and facilitate the replacement of the padding plate. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a structural diagram of an SPF-grade mouse breeding cage of the present invention; Figure 2 It is an enlarged view of the structure diagram of an SPF-grade mouse breeding cage of the present invention at position A; Figure 3 It is an enlarged view of the structure diagram B of an SPF-grade mouse breeding cage of the present invention; Figure 4It is a structural diagram of a rotating seat of an SPF-grade mouse breeding cage of the present invention; Figure 5 It is an enlarged view of the structure diagram of the rotating seat of an SPF-grade mouse breeding cage of the present invention at position C; Figure 6 This is a structural diagram of a cage body of an SPF-grade mouse breeding cage of the present invention; Figure 7 The present invention discloses a structural diagram of a risk avoidance mechanism in a first embodiment of an SPF-grade mouse breeding cage.

[0017] Among them, 1 support seat, 2 pipeline, 3 opening, 4 air nozzle, 5 connecting plate, 6 connecting end, 7 reversing rod, 8 through hole, 9 placement hole, 10 card ball, 11 iron chain, 12 grinding rod, 13 rotating plate, 14 rotating ring, 15 convex strip, 16 guard strip, 17 opening groove, 18 column, 19 limit ball, 20 slide groove, 21 cushion plate, 22 main pipe, 23 branch pipe, 24 one-way door, 25 reversing door, 28 displacement mechanism, 29 carrier frame, 30 material box, 31 material conveying mechanism, 32 discharge pipe, 33 feed trough, 34 fixed rod, 35 motor, 36 gear ring, 37 gear, 38 diode cold patch, 39 receiving barrel, 40 movable door, 41 push claw, 42 folding net, 43 push block, 44 waste recovery mechanism, 45 waste box, 46 cage. DETAILED DESCRIPTION

[0018] The specific implementation of the present invention is further described in detail below in conjunction with the accompanying drawings.

[0019] Embodiment 1: As shown in the drawings of the specification, an SPF-grade mouse breeding cage includes a support seat 1, a pipe 2 for ventilation is arranged in the middle position of the support seat 1, and an opening 3 is arranged on the pipe 2. The above contents belong to the prior art and will not be repeated here. A rotating seat for placing the cage body is rotated on the pipe 2 through a bearing. There are multiple rotating seats and they are evenly spaced along the length direction of the pipe 2. A deformable air nozzle 4 is connected to the cage body 46. The air nozzle 4 is made of rubber and has a rectangular tubular structure. A connecting plate 5 with an integral structure with the cage body 46 is arranged in the vertical direction near the air nozzle 4 on the cage body 46. There are two connecting plates 5 and they are symmetrically arranged about the air nozzle 4. Both ends of the two connecting plates 5 in the length direction are rotatably connected to the connecting end 6 through the shaft body and the torsion spring. The shaft body and the torsion spring belong to the prior art. The connecting end 6 is a rectangular plate-shaped structure, and the connecting end 6 is rotatably connected to the reversing rod 7 through a rotating shaft and a torsion spring. The rotating shaft and the torsion spring belong to the prior art, forming a structure in which the reversing rod 7 can swing horizontally and vertically under the action of the shaft and the rotating shaft, and then move out of or into the opening 3. The rotating seat includes a rotating plate 13 along a horizontal plane and a rotating ring 14 sleeved on the outside of the pipe 2, and the rotating ring 14 is rotatably connected to the pipe 2 through a bearing. The rotating plate 13 is provided with a convex strip 15 integrally formed with it, and there are multiple convex strips 15 and they are evenly spaced, forming a structure in which the convex strips 15 divide the rotating plate 13 into multiple installation positions for placing the cage 46. The cage 46 is provided with a sliding column integrally formed with it on one side close to the rotating ring 14. There are two sliding columns and they are symmetrically arranged about the center line of the cage 46. The sliding column includes a column 18 and a limit ball 19 connected to one end of the column 18. The rotating ring 14 is provided with a slide groove 20 used in conjunction with the sliding column. A padding plate 21 is provided between each cage body 46 and the rotating seat. The padding plate 21 is provided with a groove used in conjunction with the bottom surface of the cage body 46. The padding plate 21 includes an upper padding layer and a lower padding layer. The material of the upper padding layer includes but is not limited to Timothy grass, which is convenient for liquid leakage, and the debris is discharged in time when the padding plate 21 is replaced. The material of the lower padding layer includes but is not limited to sponge, which is used to absorb water and maintain a dry environment of the cage body. A guard strip 16 is provided at the edge of each installation position, and an open groove 17 is provided in the middle of the guard strip 16, forming a structure in which one end of the clip is placed in the open groove 17 and then pushes the cage body 46 to move upward. The clip belongs to the prior art and is convenient for replacing the padding plate 21. The cross-section of the reversing rod 7 is a rectangular replacement structure, and the reversing rod 7 is glued to the end of the air nozzle 4 away from the cage body 46. A through hole 8 for the reversing rod 7 to pass through is provided on the rotating seat, and there are multiple through holes 8 and they are evenly spaced. A placement hole 9 is provided on the cage body 46, and a card ball 10 is placed in the placement hole 9. One end of the card ball 10 is connected to an iron chain 11, and one end of the iron chain 11 is connected to a molar rod 12. The cage body 46 is provided with a risk avoidance mechanism for mice to avoid harm, and also includes a feeding device for feeding.

[0020] In one embodiment, as shown in the accompanying drawings, the avoidance mechanism includes a main pipe 22 fixed at the bottom of a cage body 46, one end of the main pipe 22 is connected to two branch pipes 23 of the same structure, one end of the branch pipe 23 away from the main pipe 22 is provided with a one-way door 24, and a reversing door 25 is provided between the main pipe 22 and the branch pipe 23. The reversing door 25 includes a door body and a limit plate, and the door body is rotatably connected to the main pipe 22 by a torsion spring, and can enter any branch pipe 23 through the main pipe 22 under normal conditions. The door body is a "cross" structure, and three door panels of the same width and a door strip with a width smaller than the door panel are provided on the door body. The position of the inner wall of the branch pipe 23 near the door strip under normal conditions is fixed with a limit plate by bolts, and the limit plate is made of iron, and a magnet is provided on the door panel, so that after the first mouse enters a branch pipe 23 through the reversing door 25, the door panel is blocked by the limit plate and adsorbed to prevent it from rotating by the torsion spring and cannot continue to rotate, and the reversing door 25 rotates after the second mouse hits the door panel, and the second mouse enters another branch pipe 23. The main pipe 22 and the branch pipe 23 have a side away from the bottom of the cage made of transparent material and a side close to the bottom of the cage made of non-transparent material. The main pipe 22 and the branch pipe 23 are both detachably connected to the cage, which is convenient for disassembly and cleaning of the risk avoidance mechanism. The non-transparent material at the bottom of the main pipe 22 and the branch pipe 23 can shield the position of the first mouse, and the transparent material on the top of the main pipe 22 and the branch pipe 23 makes it easy for personnel to observe the position of the mice.

[0021] In one embodiment, as shown in the accompanying drawings, the feeding device includes a feeding mechanism and a displacement mechanism 28, a control system electrically connected to the feeding mechanism and the displacement mechanism 28, the displacement mechanism 28 and the control system belong to the prior art, the feeding mechanism includes a carrier frame 29, the displacement mechanism 28 is connected to the carrier frame 29, and a structure is formed in which the carrier frame 29 moves in a set direction under the action of the displacement mechanism 28 and the control system. A material box 30 is fixed to the carrier frame 29 by support bolts, and a weighable material conveying mechanism 31 is arranged at the discharge port of the material box 30, the material conveying mechanism 31 is fixed to the carrier frame 29 by bolts, the material conveying mechanism 31 belongs to the prior art, the material conveying mechanism 31 is electrically connected to the control system, and a discharge pipe 32 is arranged at one end of the material conveying mechanism 31. A feed trough 33 is arranged at one end of the cage body 46 away from the rotating ring 14, forming a structure in which the feeding structure moves the discharge pipe 32 to the feed trough 33 under the action of the displacement mechanism 28. A fixed rod 34 is threadedly connected to one side of the support seat 1 away from the displacement mechanism 28, and a motor 35 is fixed to the fixed rod 34 through a mounting seat bolt. The motor 35 is arranged one by one with the rotating seat, and a gear ring 36 is screwed to the rotating seat around it. A gear 37 meshing with the gear ring 36 is keyed to the motor 35. The motor 35 is electrically connected to the power supply through the control system, forming a structure in which the motor 35 drives the rotating seat to rotate according to the set time under the action of the control system when feeding the mouse. A diode cold patch 38 is glued to the outer wall of the feed box 30, and a receiving barrel 39 covering the bottom of the feed box 30 is clamped to the outer wall of the feed box 30. The receiving barrel 39 is provided with a liquid outlet and a water pipe, forming a structure in which condensed water is removed through the liquid outlet and the water pipe. The feed trough 33 includes a folding net 41, which is an isosceles trapezoid, and a movable door 40 is hingedly connected to the cage body 46 through a torsion spring and a short shaft, and the short shaft is located in the middle of the movable door 40. A claw 41 for cleaning waste is rotatably connected to the cage body 46 near the feeding trough 33. The bottom surface of the feeding trough 33 includes vertical bars evenly spaced to facilitate the passage of the claw 41. Push blocks 43 are arranged on both opposite sides of the discharge pipe 32, forming a structure in which the discharge pipe 32 moves along the feeding trough 33 to push the claw 41 and the movable door 40 to rotate and clean the waste, and the discharge pipe 32 is discharged under the control system after the discharge pipe 32 retracts a set distance. A waste recovery mechanism 44 that is arranged parallel to the material conveying mechanism 31 and can be weighed is bolted to the carrier 29. The waste recovery mechanism 44 belongs to the prior art. The waste recovery mechanism 44 is electrically connected to the control system. A waste box 45 for recycling waste is screwed to the carrier 29. The control system can record and judge the actual food intake of the experimental mice based on the weighing data of the material conveying mechanism 31 and the waste recovery mechanism 44, and infer the future feeding amount.

[0022] The present invention arranges a risk avoidance mechanism in a cage body, the risk avoidance mechanism comprises a main pipe and a branch pipe, a reversing door is arranged at a position where the branch pipe is connected to the main pipe, after a first experimental mouse enters a branch pipe, a second experimental mouse can only enter another branch pipe, the fighting experimental mice are separated, and the damage caused by mutual attack of the experimental mice is reduced; the feeding mechanism comprises a feeding mechanism, a displacement mechanism and a control system, the displacement mechanism drives the discharge pipe to move in the vertical and horizontal directions, the rotating seat supporting the cage body is rotated by a motor on a fixed rod, the gear ring on the rotating plate is meshed with a gear on the motor, and the rotating seat is rotated according to a set angle under the action of the control system, so as to realize the automation of feeding.

[0023] The present invention has been described in detail above through specific implementation modes and embodiments, but these do not constitute limitations of the present invention. Without departing from the principles of the present invention, those skilled in the art may also make many variations and improvements, which should also be regarded as the protection scope of the present invention.

Claims

1. An SPF-grade mouse breeding cage, comprising a support base (1), a pipe (2) for ventilation is arranged in the middle of the support base (1), and an opening (3) is arranged on the pipe (2), characterized in that: The pipeline (2) is provided with a rotating seat for placing the cage (46), the rotating seats are provided in plurality and are evenly spaced along the length direction of the pipeline (2), the cage (46) is connected with a deformable gas nozzle (4), a connecting plate (5) is provided in the vertical direction at a position close to the gas nozzle (4) on the cage (46), the connecting plates (5) are provided in two pieces and are symmetrically arranged with respect to the gas nozzle (4), both ends of the connecting plates (5) in the length direction are rotatably connected to connecting ends (6) via an axle body and a torsion spring, the connecting ends (6) are rotatably connected to a reversing rod (7) via a rotating shaft and a torsion spring, so that the reversing rod (7) can swing in the horizontal and vertical directions under the action of the axle body and the rotating shaft. The structure for moving out of or into the opening (3) is that the cross-section of the reversing rod (7) is a rectangular structure, the reversing rod (7) is glued to one end of the air nozzle (4) away from the cage body (46), the rotating seat is provided with a through hole (8) for the reversing rod (7) to pass through, the through holes (8) are multiple and evenly spaced, the cage body (46) is provided with a placement hole (9), a locking ball (10) is provided in the placement hole (9), one end of the locking ball (10) is provided with an iron chain (11), one end of the iron chain (11) is connected to a molar rod (12), a risk avoidance mechanism for mice to avoid harm is provided in the cage body (46), and also includes a feeding device for feeding.

2. The SPF mouse breeding cage according to claim 1, characterized in that: The rotating seat comprises a rotating plate (13) rotating along a horizontal plane and a rotating ring (14) sleeved on the outside of the pipe (2), the rotating ring (14) being rotatably connected to the pipe (2) via a bearing, the rotating plate (13) being provided with a convex strip (15), the convex strip (15) being provided in plurality and evenly spaced, forming a structure in which the convex strip (15) divides the rotating plate (13) into a plurality of mounting positions for placing a cage body (46), the edge of each mounting position being provided with a guard strip (16), the middle of the guard strip (16) being provided with an open groove (17), forming a structure in which one end of the clip is placed in the open groove (17) to push the cage body (46) upward.

3. An SPF mouse breeding cage according to claim 2, characterized in that: A sliding column integral with the cage (46) is disposed on one side close to the rotating ring (14), wherein two sliding columns are symmetrically arranged about the center line of the cage (46), and the sliding column comprises a column (18) and a limiting ball (19) connected to one end of the column (18), and a sliding groove (20) used in conjunction with the sliding column is disposed on the rotating ring (14).

4. The SPF mouse breeding cage according to claim 1, characterized in that: A padding plate (21) is provided between each cage body (46) and the rotating seat, and a groove is provided on the padding plate (21) for use with the bottom surface of the cage body (46).

5. The SPF mouse breeding cage according to claim 1, characterized in that: The escape mechanism comprises a main pipe (22) detachably connected to a cage body, one end of the main pipe (22) being connected to two branch pipes (23) of the same structure and detachably connected to the cage body, one end of the branch pipe (23) being remote from the main pipe (22) being provided with a one-way door (24), a reversing door (25) being provided between the main pipe (22) and the branch pipe (23), the surface of the main pipe (22) and the branch pipe (23) remote from the bottom of the cage body being made of a transparent material and the surface of the surface close to the bottom of the cage body being made of a non-transparent material, so that a structure is formed in which a first mouse enters one branch pipe (23) through the reversing door (25) and then a second mouse enters another branch pipe (23) through the reversing door (25).

6. The SPF mouse breeding cage according to claim 1, characterized in that: The feeding device comprises a feeding mechanism and a displacement mechanism (28), and a control system electrically connected to the feeding mechanism and the displacement mechanism (28). The feeding mechanism comprises a carrier frame (29), and the displacement mechanism (28) is connected to the carrier frame (29) to form a structure in which the carrier frame (29) moves in a set direction under the action of the displacement mechanism (28) and the control system. A material box (30) is arranged on the carrier frame (29), and a weighable material conveying mechanism (31) is arranged at the discharge port of the material box (30). A discharge pipe (32) is arranged at one end of the material conveying mechanism (31), and a feed trough (33) is arranged on the cage body (46) to form a feeding structure. A structure for moving a discharge pipe (32) to a feed trough (33) under the action of a displacement mechanism (28); a fixed rod (34) is provided on a side of the support seat (1) away from the displacement mechanism (28); a motor (35) is provided on the fixed rod (34); the motor (35) and the rotating seat are arranged in a one-to-one correspondence; a gear ring (36) is provided on the rotating seat and is wound around the rotating seat; a gear (37) is provided on the motor (35) and is meshed with the gear ring (36); the motor (35) is electrically connected to a power supply through a control system, so that when feeding mice, the motor (35) drives the rotating seat to rotate according to a set time under the action of the control system.

7. The SPF mouse breeding cage according to claim 6, characterized in that: The outer wall of the material box (30) is provided with a diode cold patch (38), the outer wall of the material box (30) is provided with a receiving barrel (39), and the receiving barrel (39) is provided with a liquid outlet and a water pipe, forming a structure for condensed water to be removed through the liquid outlet and the water pipe.

8. The SPF mouse breeding cage according to claim 7, characterized in that: The feed trough (33) comprises a folding net (41) which is in an isosceles trapezoidal shape. A movable door (40) is hingedly connected to a short shaft via a torsion spring on a cage body (46). A pusher claw (41) for cleaning waste is provided at a position of the cage body (46) close to the feed trough (33). Push blocks (43) are provided on opposite sides of the discharge pipe (32). The discharge pipe (32) moves along the feed trough (33) to push the pusher claw (41) and the movable door (40) to rotate and clean waste. After the discharge pipe (32) is retracted to a set distance, the discharge is carried out under the action of a control system.

9. The SPF mouse breeding cage according to claim 8, characterized in that: The support frame (29) is provided with a waste material recovery mechanism (44) which is arranged in parallel with the material conveying mechanism (31) and can be weighed, and the support frame (29) is provided with a waste material box (30) for recovering waste materials.

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