Traditional Chinese medicine composition for treating gastrointestinal excess heat type hyperlipemia acute pancreatitis and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating gastrointestinal excess heat type hyperlipemia acute pancreatitis and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition consists of the following medicines in parts by weight: 14-18 parts of raw rhubarb, 28-32 parts of immature bitter orange, 16-20 parts of mangnolia officinalis, 18-22 parts of mirabilite, 16-20 parts of radix paeoniae rubra, 28-32 parts of moutan bark, 28-32 parts of dandelion, 28-32 parts of pericarpium arecae, 28-32 parts of fried hawthorn, 8-12 parts of coptis chinensis and 8-12 parts of scutellaria baicalensis. The preparation method comprises the following steps: mixing the traditional Chinese medicine raw materials, and adding water for soaking; boiling with strong fire, decocting with slow fire, and filtering to obtain a first filtrate; adding water into filter residues, boiling with strong fire, decocting with slow fire, and filtering to obtain a second filtrate; and combining the two filtrates, and concentrating to obtain the traditional Chinese medicine composition. The traditional Chinese medicine has the effects of clearing heat, relieving pain, dredging interior and attacking the lower part, can effectively control the development of illness state and relieve the symptoms of abdominal pain and abdominal distension when being used for treating gastrointestinal excess heat type hyperlipemia acute pancreatitis, and is rapid in curative effect and low in price.

Description

Technical Field

[0001] The invention belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating gastrointestinal excess heat type hyperlipidemic acute pancreatitis and a preparation method thereof. Background Art

[0002] Hyperlipidemic acute pancreatitis (HLAP) is one of the common causes of acute pancreatitis. In recent years, with the improvement of living standards and changes in dietary structure, the incidence rate has increased and has become a common cause of acute pancreatitis. HLAP is characterized by persistent upper or left upper abdominal pain, abdominal distension, and vomiting, but it is more likely to develop persistent organ failure, and is characterized by severe illness, higher incidence of complications and mortality, and easy recurrence.

[0003] Early and rapid reduction of blood lipids is crucial to improve the success rate of treatment of HLAP patients and reduce the mortality rate. Therefore, the importance of reducing the blood TG level of HLAP patients has also attracted more and more attention. At present, there are no effective drugs and exact treatment standards for the treatment of HLAP in clinical practice. The treatment of HLAP is mainly based on comprehensive internal medicine treatment, including conventional treatment and specific treatment. Conventional treatment mainly includes fasting and water, early fluid resuscitation, gastrointestinal decompression, nutritional support, inhibition of pancreatic enzyme secretion, etc. For patients with combined shock, they should actively resist shock and correct water and electrolyte disorders. In recent years, research on the prevention and treatment of HLAP with traditional Chinese medicine has made certain progress, and its advantages are becoming increasingly prominent. Therefore, seeking the best means and methods for traditional Chinese medicine to intervene or block the progression of HLAP and prevent further deterioration of the disease is currently a hot topic in HLAP research. It is of great scientific significance to carry out research on the treatment of HLAP with traditional Chinese medicine.

[0004] Hyperlipidemic acute pancreatitis belongs to the category of "abdominal pain", "chest congestion", "spleen and heart pain" in traditional Chinese medicine. Its pathogenesis is that overeating rich and greasy food, overeating, etc. damage the spleen and stomach, the spleen loses the ability to disperse essence, the water and grain transportation is abnormal, and the fat essence is stored and accumulated in the body, causing hyperlipidemia and lipid metabolism disorder, which is endogenous fat turbidity. Fat turbidity will inevitably increase the load of spleen gasification and dispersion of essence, thereby further aggravating blood lipid disorder. Fat turbidity stagnates and turns into heat, or combines with heat evil to form stasis heat, accumulates in the stomach and intestines, blocks the qi mechanism, and the qi and blood flow is not smooth, blood vessels are blocked, causing abdominal pain. Patients often show red tongue, thick yellow fur, and stringy pulse, which are mostly gastrointestinal heat syndrome. As the saying goes, "pain occurs when there is no circulation", so the treatment often adopts the method of "clearing the interior and attacking the lower part, activating blood circulation and removing blood stasis", so this decoction is formulated to achieve the effect of "no pain when there is circulation". Oral administration of this decoction can not only improve clinical efficacy but also shorten the course of the disease and reduce the economic burden on patients and society. It has important academic value and practical significance. Summary of the invention

[0005] In view of the above situation, in order to solve the defects of the prior art, the purpose of the present invention is to provide a decoction for treating gastrointestinal heat type hyperlipidemic acute pancreatitis, which can effectively solve the problems of visceral qi stagnation and blood vessel stasis.

[0006] The present invention adopts the following technical scheme: a traditional Chinese medicine composition for treating hyperlipidemic acute pancreatitis of gastrointestinal excess heat type, which is composed of the following medicines in parts by weight: 14-18 parts of raw rhubarb, 28-32 parts of immature bitter orange, 16-20 parts of magnolia bark, 18-22 parts of sodium sulfate, 16-20 parts of red peony root, 28-32 parts of peony bark, 28-32 parts of dandelion, 28-32 parts of dried tangerine peel, 28-32 parts of stir-fried hawthorn, 8-12 parts of coptis root, and 8-12 parts of scutellaria.

[0007] Among the various Chinese medicines in the above formula: Raw rhubarb: It is the main drug, bitter and cold; Functions and indications: purgative, clearing away heat and purging fire, cooling blood and detoxifying, removing blood stasis and promoting menstruation, removing dampness and relieving jaundice. It is used for constipation caused by excess heat accumulation, vomiting and bleeding due to blood heat, red eyes and swollen throat, carbuncle, abdominal pain due to intestinal carbuncle, amenorrhea caused by blood stasis, postpartum blood stasis, traumatic injury, damp-heat dysentery, jaundice and red urine, stranguria, edema; external treatment for burns and scalds.

[0008] Zhishi: It is a ministerial drug, bitter, pungent, sour, and slightly cold; Functions and indications: It can break up qi and eliminate stagnation, resolve phlegm and relieve lumps. It is used for stagnation of internal stagnation, fullness and pain in the lumps, heaviness after diarrhea, constipation, phlegm stagnation and qi obstruction, chest pain, chest congestion, and sagging of internal organs.

[0009] Magnolia officinalis: It is a ministerial drug, bitter, pungent, and warm; Functions and indications: It dries dampness and eliminates phlegm, relieves qi and relieves fullness. It is used for dampness stagnation, abdominal distension, vomiting and diarrhea, food accumulation and qi stagnation, abdominal distension and constipation, and cough with phlegm and fluid.

[0010] Glauber's Salt: It is an adjuvant drug, salty, bitter, and cold; Functions and indications: laxative, moistening, softening, clearing away heat and reducing swelling. It is used for excess heat stagnation, abdominal distension and pain, dry stool, intestinal carbuncle swelling and pain; external treatment of breast carbuncle, hemorrhoid swelling and pain.

[0011] Red peony root: adjuvant, bitter, slightly cold; Functions and indications: clearing heat and cooling blood, dispersing blood stasis and relieving pain. Used for heat entering the blood, fever toxicity causing rash, vomiting blood and epistaxis, red and swollen eyes, liver depression and flank pain, amenorrhea and dysmenorrhea, abdominal pain due to lumps and masses, injuries from falls, carbuncles and ulcers.

[0012] Peony bark: It is an adjuvant drug, bitter, pungent, slightly cold; Functions and indications: cools blood and clears heat, activates blood circulation and removes blood stasis. It is used for heat entering the blood, fever and rashes, vomiting blood and bleeding, night heat and morning coolness, no sweat and bone steaming, amenorrhea, dysmenorrhea, pain from falls and injuries, carbuncle, swelling and sores.

[0013] Taraxacum: It is an adjuvant, bitter, sweet and cold; Functions and indications: clearing away heat and detoxifying, reducing swelling and dispersing stagnation, diuresis and relieving stranguria. It is used for carbuncle, breast carbuncle, scrofula, red eyes, sore throat, lung carbuncle, intestinal carbuncle, damp-heat jaundice, and hot stranguria with astringent pain.

[0014] Rhizoma Cibotii: adjuvant, pungent, slightly warm; Functions and indications: promotes qi and relieves fullness, promotes water and reduces swelling. Used for dampness blocking qi stagnation, abdominal distension, uncomfortable bowel movements, edema, beriberi edema, and difficulty urinating.

[0015] Fried Hawthorn: It is an adjuvant, sour, sweet, and slightly warm; Functions and indications: helps digestion and strengthens the stomach, promotes qi and dissipates blood stasis, removes turbidity and reduces fat. It is used for meat stagnation, stomach distension, diarrhea and abdominal pain, blood stasis and amenorrhea, postpartum blood stasis, heart and abdomen stabbing pain, chest pain, hernia pain, and hyperlipidemia.

[0016] Coptis chinensis: adjuvant, bitter, cold; Functions and indications: clearing away heat and dampness, purging fire and detoxifying. Used for damp-heat fullness, vomiting and acid regurgitation, diarrhea, jaundice, high fever and coma, hyperactivity of heart fire, restlessness and insomnia, vomiting and bleeding due to blood heat, red eyes, toothache, thirst, carbuncle, furuncle; external treatment of eczema, wet sores, pus in the ear canal.

[0017] Scutellaria baicalensis: adjuvant, bitter, cold; Functions and indications: clearing away heat and dampness, purging fire and detoxifying, stopping bleeding, and calming the fetus. Used for damp-heat, summer-heat, chest tightness and nausea, damp-heat fullness, diarrhea, jaundice, lung heat cough, high fever and thirst, blood heat vomiting and bleeding, carbuncle, sore, and restless fetus.

[0018] Hyperlipidemic acute pancreatitis belongs to the category of "abdominal pain", "chest congestion", "spleen and heart pain" in traditional Chinese medicine. Its pathogenesis is that overeating rich and greasy food, overeating, etc. damage the spleen and stomach, the spleen loses its essence, the water and grain transportation is abnormal, and the fat essence is stored and accumulated in the body, causing hyperlipidemia and lipid metabolism disorder, which is endogenous fat turbidity. Fat turbidity will inevitably increase the load of spleen gasification and essence dispersion, thereby further aggravating blood lipid disorder. Fat turbidity stagnates and turns into heat, or combines with heat evil to form stasis heat, accumulates in the gastrointestinal tract, blocks the qi mechanism, and the qi and blood flow is not smooth, blood vessels are blocked, causing abdominal pain. As the saying goes, "no smoothness leads to pain", so the treatment often adopts the method of "clearing the interior and attacking the lower, activating blood circulation and stopping pain". The research team used this prescription to treat hyperlipidemic acute pancreatitis and conducted relevant clinical research for nearly 20 years. It was found that this prescription can resist inflammation, improve lipid metabolism and gastrointestinal motility and microcirculation, so this prescription was formulated to achieve the effect of "no pain if smooth".

[0019] Preferably, the present invention is composed of the following medicines in parts by weight: 15-16 parts of raw rhubarb, 30-32 parts of immature bitter orange, 16-18 parts of magnolia bark, 18-20 parts of sodium glauber's salt, 18-20 parts of red peony root, 20-32 parts of peony bark, 28-30 parts of dandelion, 28-30 parts of dried tangerine peel, 30-32 parts of stir-fried hawthorn, 8-10 parts of coptis root, and 10-12 parts of scutellaria.

[0020] Preferably, it is composed of the following drugs in parts by weight: 15 parts of raw rhubarb, 30 parts of immature bitter orange, 18 parts of magnolia bark, 20 parts of sodium sulfate, 18 parts of red peony root, 30 parts of peony bark, 30 parts of dandelion, 30 parts of dried tangerine peel, 30 parts of stir-fried hawthorn, 10 parts of coptis root, and 10 parts of scutellaria.

[0021] Furthermore, the present invention is a traditional Chinese medicine preparation for treating gastrointestinal heat-type hyperlipidemic acute pancreatitis, which is prepared from any one of the above-mentioned traditional Chinese medicine compositions.

[0022] Preferably, the Chinese medicine preparation is a decoction.

[0023] The preparation method of the Chinese medicine preparation of the present invention comprises the following steps: (1) After mixing the Chinese medicinal materials, add water 1.8 to 2.5 times the total weight of the Chinese medicinal materials, and soak at 18 to 25° C. for 15 to 25 minutes; (2) Bring to a boil over high heat, then simmer over low heat for 20 to 30 minutes, and filter to obtain the first filtrate; (3) Add 1.4 to 1.8 times the total weight of the raw materials to the residue, bring to a boil over high heat, then simmer over low heat for 10 to 15 minutes, and filter to obtain the second filtrate; (4) Combine the two filtrates and concentrate to 1 / 2 to 1 / 3 of the original amount of water added.

[0024] Preferably, in steps (1) and (2), raw rhubarb is soaked alone, and other Chinese medicinal materials are simmered over low heat for 10 to 20 minutes before being added.

[0025] The Chinese medicine preparation of the invention is used to treat hyperlipidemic acute pancreatitis of gastrointestinal heat type, and the decoction is taken with mirabilite.

[0026] Compared with the prior art, the present invention has the following beneficial effects: 1. The invention has the effects of clearing away heat and relieving pain, and clearing the interior and attacking the lower part. In the treatment of hyperlipidemic acute pancreatitis of gastrointestinal heat type, it can effectively control the development of the disease, relieve abdominal pain and bloating symptoms, has rapid efficacy and low price.

[0027] 2. The present invention is safe to take and has good efficacy. It is an effective medicine for treating hyperlipidemic acute pancreatitis of gastrointestinal heat type, and is proven by clinical data. DETAILED DESCRIPTION

[0028] The specific implementation modes of the present invention are described below in conjunction with embodiments and clinical examples. However, the following embodiments and clinical examples are only used to illustrate the present invention in detail and do not limit the scope of the present invention in any way.

[0029] Example 1: A Chinese medicine composition for treating gastrointestinal hyperlipidemic acute pancreatitis of excess heat type, composed of the following drugs in parts by weight: 14g of raw rhubarb (added later), 32g of immature bitter orange, 16g of Magnolia officinalis, 22g of Glauber's salt (taken with water), 16g of red peony root, 32g of peony bark, 28g of dandelion, 32g of dried big belly peel, 28g of stir-fried hawthorn, 12g of Coptis chinensis, and 8g of Scutellaria baicalensis.

[0030] The above Chinese medicine composition is prepared into a decoction, and the preparation method is as follows: (1) Mix the Chinese medicinal materials (except for Glauber's salt and rhubarb), add 1.5 times the total weight of the Chinese medicinal materials in water, and soak at 18°C ​​for 15 minutes; (2) Bring to a boil over high heat, then simmer over low heat for 20 minutes (add rhubarb when the rhubarb has been boiled for 15 minutes), and filter to obtain the first filtrate; (3) Add 1.5 times the total weight of the raw materials to the residue, bring to a boil over high heat, then simmer over low heat for 10 min, and filter to obtain the second filtrate; (4) Combine the two filtrates and concentrate to 1 / 3 of the original amount of water added.

[0031] In the treatment of hyperlipidemic acute pancreatitis of gastrointestinal heat type, this decoction is taken with Glauber's salt.

[0032] Example 2: A Chinese medicine composition for treating gastrointestinal heat-type hyperlipidemic acute pancreatitis, composed of the following drugs in parts by weight: 15g of raw rhubarb (added later), 30g of immature bitter orange, 18g of Magnolia officinalis, 20g of Glauber's salt (taken with water), 18g of red peony root, 30g of peony bark, 30g of dandelion, 30g of dried big belly peel, 30g of stir-fried hawthorn, 10g of Coptis chinensis, and 10g of Scutellaria baicalensis.

[0033] The above Chinese medicine composition is prepared into a decoction, and the preparation method is as follows: (1) Mix the Chinese medicinal materials (except for Glauber's salt and rhubarb), add 2.5 times the total weight of the Chinese medicinal materials in water, and soak at 20°C for 20 minutes; (2) Bring to a boil over high heat, then simmer over low heat for 30 minutes (add rhubarb when the rhubarb is simmered for 25 minutes), and filter to obtain the first filtrate; (3) Add 1.8 times the total weight of the raw materials to the residue, bring to a boil over high heat, then simmer over low heat for 15 min, and filter to obtain the second filtrate; (4) Combine the two filtrates and concentrate to 1 / 2 of the original amount of water added.

[0034] The Chinese medicine preparation of the invention is used to treat hyperlipidemic acute pancreatitis of gastrointestinal heat type, and the decoction is taken with mirabilite.

[0035] The relevant clinical data of the present invention are as follows: Clinical Case 1: Hu, male, 35 years old, No. 48, Nange Street, Fengrui Sub-district Office, Fangcheng County, Nanyang City, Henan Province. The patient had abdominal pain and discomfort without obvious cause one day ago, mainly in the upper left abdomen, with persistent distension and pain, accompanied by nausea and vomiting, palpitations, chest tightness, general fatigue, abdominal distension, acid reflux, heartburn, dry mouth and bitter taste, sweating, no fever, diarrhea, no vomiting blood, and no black stools. Without relevant diagnosis and treatment, the abdominal pain progressively worsened and became unbearable. Abdominal CT scan at the local hospital showed acute pancreatitis. For further diagnosis and treatment, the patient came to the emergency department of our hospital. The emergency department diagnosed him with "acute pancreatitis" and he was admitted to our department on 2024-04-30. After admission, combined with the medical history, pancreatic CT, biochemistry (triglyceride 14.56mmol / L) and other results, he was diagnosed with "hyperlipidemia acute pancreatitis". Chinese medicine diagnosis was gastrointestinal heat syndrome, and the treatment was based on clearing heat, dredging the bowels, promoting blood circulation and relieving pain. Basic treatment was given plus oral administration of this decoction. After 2 days, the patient's abdominal pain, bloating, and nausea symptoms disappeared. After 8 days of hospitalization, blood amylase and triglycerides were normal, and lipase was significantly lower than before. Reexamination of CT showed that the pancreatic exudation was less than before.

[0036] Clinical Case 2: Dang Moumou, male, 35 years old, No. 8, Changjiang Road, Erqi District, Zhengzhou City. The patient had abdominal pain and discomfort after eating "hot pot" and other greasy foods 8 hours ago. It was mainly located in the upper left abdomen, with persistent distension and pain, radiating to the lower back, accompanied by nausea, palpitations, chest tightness, general fatigue, abdominal distension, no fever, diarrhea, no vomiting blood, black stools and other discomforts. The abdominal pain was progressively aggravated, the abdominal pain was unbearable, and sweating profusely. For further diagnosis and treatment, he came to our outpatient clinic for treatment. The outpatient clinic was admitted to the hospital for "acute pancreatitis" (2024-05-01). Combined with the medical history, pancreatic CT, and biochemical examination (triglyceride 22.14mmol / L), the patient was diagnosed with "hyperlipidemic acute pancreatitis". The TCM syndrome differentiation was gastrointestinal heat syndrome. The treatment was to clear away heat and dredge the bowels, promote blood circulation and relieve pain. Basic treatment was given plus oral administration of this decoction. After 1 day, the symptoms of abdominal pain, abdominal distension, and nausea disappeared. After 10 days of hospitalization, blood amylase and lipase were normal, triglycerides were significantly lower than before, and pancreatic CT scan showed that the absorption of pancreatitis had improved compared with 05-01.

[0037] Clinical Case 3: Song Moumou, male, 52 years old, Shangjingxiuyuan, Jinguang Road Office, Jinshui District, Zhengzhou City. The patient had abdominal pain and discomfort without obvious cause 3 hours ago, mainly in the upper abdomen, with persistent dull pain, radiating to the lower back, accompanied by nausea, abdominal distension, palpitation, chest tightness, fatigue, dry mouth and bitter taste, sweating, no fever, diarrhea, vomiting blood, black stool, etc. The pain was progressively aggravated. In order to seek systematic treatment, he was admitted to our department for treatment on June 24, 2024. After admission, combined with medical history, biochemistry (triglyceride 25.22mmol / L) and pancreatic CT and other examinations, it was clearly diagnosed as "hyperlipidemic acute pancreatitis". The traditional Chinese medicine syndrome differentiation was gastrointestinal heat syndrome. The treatment was based on clearing heat and dredging the bowels, promoting blood circulation and relieving pain. The basic treatment was given with the drug of the present invention. After 2 days, the symptoms of abdominal pain, nausea and bloating basically disappeared, and triglycerides gradually decreased. After more than 10 days of hospitalization, the CT examination showed that the periplasmic exudation was less than before, TG was normal, and the condition improved and was discharged from the hospital.

[0038] Clinical Case 4: Hong, male, 37 years old, Room 10, No. 10 Maoxiang, Licheng District, Quanzhou City, Fujian Province. The patient had abdominal pain after eating too much one day ago, mainly in the upper abdomen, with persistent dull pain, radiating to the right posterior waist, accompanied by nausea, palpitations, chest tightness, abdominal distension, fatigue, no fever, diarrhea, no acid reflux, heartburn, and no attention was paid at the time, and no relevant diagnosis and treatment was performed. During the period, the pain did not ease, progressively worsened, and the pain was unbearable. In order to seek further treatment, he was admitted to our department on 2024-07-11. After admission, combined with medical history, biochemistry (triglyceride 48.51mmol / L) and pancreatic CT examination, it was clearly diagnosed as "hyperlipidemic acute pancreatitis". The traditional Chinese medicine syndrome differentiation was gastrointestinal heat syndrome. The treatment method was to clear heat and dredge the bowels, promote blood circulation and relieve pain. Basic treatment was given plus this decoction for oral administration. On the third day, the symptoms of abdominal pain and nausea disappeared. After 7 days of hospitalization, recheck of triglyceride level was 3.17 and CT scan showed that pancreatitis had improved compared to before. The patient was discharged from the hospital after his condition improved.

[0039] The present invention has been described in detail above with reference to the embodiments and clinical examples; however, those skilled in the art will appreciate that, without departing from the concept of the present invention, the specific parameters in the above embodiments may be changed to form a plurality of specific embodiments, which are all within the common variation range of the present invention and will not be described in detail one by one.

Claims

1. A Chinese medicine composition for treating gastrointestinal heat type hyperlipidemic acute pancreatitis, characterized in that: The invention is composed of the following medicines in parts by weight: 14-18 parts of raw rhubarb, 28-32 parts of immature bitter orange, 16-20 parts of magnolia bark, 18-22 parts of sodium sulfate, 16-20 parts of red peony root, 28-32 parts of peony bark, 28-32 parts of dandelion, 28-32 parts of dried tangerine peel, 28-32 parts of stir-fried hawthorn, 8-12 parts of coptis root and 8-12 parts of scutellaria.

2. The Chinese medicine composition according to claim 1, characterized in that: The invention is composed of the following medicines in parts by weight: 15-16 parts of raw rhubarb, 30-32 parts of immature bitter orange, 16-18 parts of magnolia bark, 18-20 parts of sodium sulfate, 18-20 parts of red peony root, 20-32 parts of peony bark, 28-30 parts of dandelion, 28-30 parts of dried tangerine peel, 30-32 parts of stir-fried hawthorn, 8-10 parts of coptis root and 10-12 parts of scutellaria.

3. The Chinese medicine composition according to claim 1, characterized in that The medicine is composed of the following medicines in parts by weight: 15 parts of raw rhubarb, 30 parts of immature bitter orange, 18 parts of magnolia bark, 20 parts of sodium sulfate, 18 parts of red peony root, 30 parts of peony bark, 30 parts of dandelion, 30 parts of dried tangerine peel, 30 parts of stir-fried hawthorn, 10 parts of coptis root and 10 parts of scutellaria.

4. A Chinese medicine preparation for treating gastrointestinal heat type hyperlipidemic acute pancreatitis, characterized in that: The Chinese medicine preparation is prepared from the Chinese medicine composition according to any one of claims 1 to 3.

5. The Chinese medicine preparation according to claim 4, characterized in that: The Chinese medicine preparation is a decoction.

6. A method for preparing the Chinese medicine preparation according to claim 5, characterized in that: The following steps are involved: (1) After mixing the Chinese medicinal materials, add water 1.8 to 2.5 times the total weight of the Chinese medicinal materials, and soak at 18 to 25° C. for 15 to 25 minutes; (2) Bring to a boil over high heat, then simmer over low heat for 20 to 30 minutes, and filter to obtain the first filtrate; (3) Add 1.4 to 1.8 times the total weight of the raw materials to the residue, bring to a boil over high heat, then simmer over low heat for 10 to 15 minutes, and filter to obtain the second filtrate; (4) Combine the two filtrates and concentrate to 1 / 2 to 1 / 3 of the original amount of water added.

7. The preparation method according to claim 6, characterized in that: In steps (1) and (2), raw rhubarb is soaked alone, and other Chinese medicinal materials are simmered over low heat for 10 to 20 minutes before being added.

8. An application of the Chinese medicine preparation according to claim 5, characterized in that: For the treatment of hyperlipidemic acute pancreatitis of gastrointestinal heat type, take this decoction with Glauber's salt.