Extraction device for pyrimidine compound production and use method thereof

Abstract

The invention provides an extraction device for pyrimidine compound production and a use method thereof, and belongs to the technical field of pyrimidine compound production and extraction. Comprising a first tank body and a second tank body, a driving motor is arranged at the top end of the first tank body, a stirring barrel and a discharging barrel are arranged in the first tank body, a detachable driving rod is installed at the output end of the driving motor, and movable stirring blades located in the stirring barrel are fixedly connected to the peripheral side wall of the driving rod; the first tank body and the second tank body are fixedly connected with a first air pipe and a second air pipe respectively, and the first air pipe and the second air pipe are both connected with external temperature control equipment, so that the first tank body, the second tank body and the external temperature control equipment form a heating channel through the first air pipe and the second air pipe; a plurality of standing cavities are formed in the second tank body, residual liquid cavities are formed in the bottom ends of the plurality of standing cavities, and filter material structures are mounted between the standing cavities and the residual liquid cavities. By arranging the conversion assembly, the production efficiency is effectively improved, and the purpose of sustainable production is achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of production and extraction of pyrimidine compounds, and in particular to an extraction device for production of pyrimidine compounds and a use method thereof. Background Art

[0002] Pyrimidine compounds are a class of six-membered heterocyclic compounds containing two nitrogen atoms in their molecular structure. Their derivatives are widely used in the fields of pharmaceutical raw materials and dye raw materials. During the mixing process, the original solution containing the target compound is mixed with the extractant to form a two-phase system, and the target compound is distributed between the two phases. During the extraction process, since the two solvents are immiscible with each other, they will naturally separate into layers. In order to ensure that the two phases are completely separated, a long standing time is usually required. For example, in some synthesis steps, the reaction solution needs to be left standing for a period of time after the extractant is added, usually several hours.

[0003] In the prior art, after the mixed liquid is mixed, it must enter a standing chamber to wait for the extraction process to be completed before adding new mixed liquid. This is to prevent the newly added mixed liquid from interfering with the previously added mixed liquid. However, the standing stratification time is relatively long, and other operations cannot be performed during this period, thus affecting the overall production efficiency; in addition, when extracting specific pyrimidine compounds, it is necessary to react within a specific temperature range, such as between -25°C and 120°C. At this time, a constant temperature control device is required. Usually, hot air is used to heat the tank body. However, since the tank body is large, the liquid inside the tank body cannot be heated evenly after heating, thus affecting the constant temperature efficiency; in addition, foam is easily generated during the stirring process of the mixed liquid. If these foams are not processed, during the standing stratification, the foam will increase the surface area of ​​the liquid, resulting in a decrease in the contact area between the liquid phases, thereby hindering the mass transfer process and reducing the extraction efficiency. Therefore, the present application provides an extraction device for the production of pyrimidine compounds and a method for using the same to meet the needs. Summary of the invention

[0004] The technical problem to be solved by the present invention is to provide an extraction device for producing pyrimidine compounds and a method of using the same to solve the problems that the existing extraction device cannot operate continuously, has uneven constant temperature heating, and is easily affected by foam in terms of extraction efficiency.

[0005] In order to solve the above technical problems, the present invention provides the following technical solutions: An extraction device for producing pyrimidine compounds comprises a first tank body and a second tank body, wherein a driving motor is arranged at the top of the first tank body, a stirring drum and a feeding drum are arranged in the first tank body, a detachable driving rod is installed at the output end of the driving motor, and a stirring blade movable in the stirring drum is fixedly connected to the peripheral side wall of the driving rod; a first air pipe and a second air pipe are fixedly connected to the first tank body and the second tank body respectively, and the first air pipe and the second air pipe are both connected to an external temperature control device, so that the first tank body, the second tank body and the external temperature control device form a heating channel through the first air pipe and the second air pipe; a plurality of static chambers are arranged in the second tank body, and a residual liquid chamber is arranged at the bottom end of the plurality of static chambers, and a filter material structure is installed between the static chamber and the residual liquid chamber; and a conversion component installed between the plurality of static chambers is also included, which is automatically closed when the current static chamber is filled with a mixed liquid, and the next static chamber is opened and collects the mixed liquid.

[0006] Optionally, the conversion assembly includes a lower liquid hopper and a fixed cylinder fixedly connected to the bottom end of the lower material cylinder, a plurality of downpipes are fixedly connected to the outer peripheral side walls of the fixed cylinder, and the plurality of downpipes are respectively connected to a plurality of static chambers, a fixed ring body is rotatably connected inside the fixed cylinder, and a through opening is opened on the peripheral side walls of the fixed ring body; a fixed pipe is fixedly connected to the bottom end of the fixed ring body, a mounting seat is fixedly connected to the bottom end of the fixed cylinder, the fixed pipe is inserted into the mounting seat, and a bearing is installed between the mounting seat and the fixed pipe.

[0007] Optionally, a pair of slide grooves are opened in the fixed ring body, and the pair of slide grooves are respectively located on opposite sides of the through opening, and a slide rod is limited to slide in the pair of slide grooves, and a first spring is sleeved on the surrounding side walls of the pair of slide rods, and a pair of slide rods are commonly fixedly connected to a support rod at one end facing the sewer pipe, and a support plate is fixedly connected to the outer wall of the support rod, and first rollers are fixedly connected to both ends of the support plate, and the support plate is inclined, and there is an arc structure between several of the sewer pipes.

[0008] Optionally, several support frames are fixedly connected in the several sewer pipes, and push rods and connecting ropes are slidably connected in the several support frames respectively. The push rods and the connecting ropes are fixed to each other, and one end of the push rod away from the connecting rope is rotatably connected to a second roller, one end of the connecting rope away from the push rod is fixedly connected to a cone head, and a second spring is sleeved between the push rod and the support frame.

[0009] Optionally, a floating plate is fixedly connected to the bottom end of the cone head, a plurality of lower water grooves are provided on the top wall of the floating plate, the plurality of lower water grooves are arranged in a ring with the cone head as the center, a plurality of lower water pipes are fixedly connected to a baffle cover at one end away from the fixed cylinder, and the cone head is located below the baffle cover.

[0010] Optionally, a plurality of planes are formed on the side walls around the driving rod, and a pair of sliding rods are fixedly connected to a fixing frame toward one end of the driving rod, the connection between the fixing frame and the sliding rod is a curved structure, and the fixing frame is in contact with the plurality of planes; the driving rod passes through the mixing drum, the unloading drum and the fixed drum in sequence, and a fan blade located below the fixed drum is fixedly connected to the bottom end of the driving rod, and the driving rod and the mixing drum are rotatably connected via a sealed bearing, and a scraper is fixedly connected to the side walls around the driving rod, and the scraper is in contact with a mesh plate detachably installed in the fixed drum.

[0011] Optionally, the top and bottom ends of the lower barrel are fixedly connected to fixed plates, a spiral plate and a number of staggered baffle tubes are fixedly connected inside the lower barrel, the several baffle tubes penetrate the spiral plate and the fixed plate, and a mixing channel is formed between the several baffle tubes; a guide tube is fixedly connected between the mixing barrel and the lower barrel, a number of lower liquid ports connected to the guide tube are opened on the inner wall of the lower barrel, a connecting pipe is installed between the mixing barrel and the guide tube, and a valve is installed on the connecting pipe.

[0012] The present application also provides a method for using an extraction device for producing pyrimidine compounds, comprising the following steps: S1. First, add the original solution containing the target substance and the extractant into the stirring drum, then start the driving motor for stirring, and start the external constant temperature equipment to transport hot air into the tank through the second air pipe; S2. After the required stirring time is reached, the valve is opened to allow the mixed liquid in the mixing cylinder to enter the lower cylinder for re-mixing and constant temperature heating. The mixed liquid in the lower cylinder enters the fixed cylinder through the lower liquid hopper; S3, the mixed liquid in the fixed cylinder enters the static chamber through the conversion component for static treatment, and the current static chamber is automatically closed after the liquid is filled, and the next static chamber is opened at the same time; S4. The mixed liquid in the static chamber is processed by the filter material structure, the filter material structure blocks and filters the extraction phase in the mixed liquid, and the raffinate enters the raffinate chamber through the filter material structure.

[0013] Compared with the prior art, the present invention has at least the following beneficial effects: In the above scheme, by setting a conversion component, when the mixed liquid gradually fills the static chamber, the current static chamber is automatically closed and the next static chamber is automatically opened. Therefore, during the production process, there is no need to wait for the mixed liquid in the current static chamber to be extracted, and the subsequent addition of the mixed liquid will not interfere with the previous work flow, thereby effectively improving production efficiency and achieving the goal of sustainable production.

[0014] By arranging a mesh plate and a scraper on the driving rod, the foam is blocked by the mesh plate when the mixed liquid enters the sewer pipe through the fixed cylinder, while the liquid can flow into the sewer pipe through the mesh plate, effectively preventing the bubbles from entering the static chamber to affect the mass transfer process and reduce the extraction efficiency. Since the scraper can scrape the foam on the mesh plate, it can not only prevent the foam from further accumulating and affecting the conveying efficiency, but also make the broken foam turn into liquid and continue to flow into the fixed cylinder through the mesh plate, thereby reducing material waste.

[0015] By setting up a lower barrel, not only can the residence time of the mixed liquid in the channel be prolonged, but the curved mixing channel also allows the mixed liquid to repeatedly collide and mix in the curved mixing channel, thereby helping to improve the mixing effect of the mixed liquid; in addition, since the baffle tube is hollow, when the hot air flows through the baffle tube, the contact between the mixed liquid and heat can be improved, which is beneficial to improving the constant temperature uniformity of the mixed liquid and improving the efficiency of the subsequent extraction process; by setting fan blades at the bottom end of the driving rod, when the hot air enters the second tank body through the second air pipe, the driving rod drives the fan blades to rotate, so that the hot air entering the second tank body is transported into the first tank body, which is beneficial to the flow of hot air and improves uniformity. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] The accompanying drawings, which are incorporated herein and constitute a part of the specification, illustrate embodiments of the invention and, together with the description, further serve to explain the principles of the invention and to enable those skilled in the relevant art to make and use the invention.

[0017] Figure 1 A schematic diagram of the three-dimensional structure of an extraction device for producing pyrimidine compounds and a method of using the same; Figure 2 for Figure 1 A schematic cross-sectional structure diagram of ; Figure 3 is a schematic diagram of the cross-sectional structure of the second tank body; Figure 4 It is a schematic diagram of the three-dimensional structure of the sewer pipe; Figure 5 for Figure 2 The enlarged structural diagram at A in the middle; Figure 6 for Figure 4 The enlarged structural diagram at B in the middle; Figure 7 It is a schematic diagram of the cross-sectional structure of the fixed tube from the first perspective; Figure 8 is a schematic diagram of the three-dimensional structure of the driving rod; Fig. 9 This is a schematic diagram of the three-dimensional structure of the lower barrel from the first perspective; Fig.10 This is a schematic diagram of the three-dimensional structure of the lower barrel from the second viewing angle; Fig.11It is a schematic diagram of the three-dimensional structure of the spiral plate; Fig.12 It is a schematic diagram of the cross-sectional structure of the lower barrel; Fig.13 for Fig.12 The enlarged structural diagram at C in the middle; Fig.14 It is a schematic diagram of the cross-sectional structure of the fixed tube from the second viewing angle; Fig.15 for Fig.14 The enlarged structural diagram at D in the middle; Fig.16 for Fig.14 The enlarged structural diagram at E in the middle; Fig.17 for Fig.15 The enlarged structural diagram at F in the middle; Fig.18 It is a schematic diagram of the cross-sectional structure of the baffle cover; Fig.19 for Figure 2 Enlarged structural diagram at G in the middle.

[0018] Reference numerals: 1. First tank body; 2. Second tank body; 3. Driving motor; 4. First air pipe; 5. Mounting seat; 6. Driving rod; 7. Stirring blade; 8. Fan blade; 9. Scraper; 10. Stirring drum; 11. Discharging drum; 12. Lower liquid bucket; 13. Guide drum; 14. Lower liquid port; 15. Fixed plate; 16. Spiral plate; 17. Mixing channel; 18. Baffle tube; 19. Fixed drum; 20. Downpipe; 21. Fixed ring body; 22. Plane; 23. Fixed frame; 24. Curved structure; 25. Through port ; 26. slide groove; 27. first spring; 28. slide rod; 29. ​​support rod; 30. support plate; 31. first roller; 32. arc structure; 33. push rod; 34. second roller; 35. support frame; 36. second spring; 37. connecting rope; 38. cone head; 39. floating plate; 40. lower sink; 41. baffle; 42. static chamber; 43. residual liquid chamber; 44. filter material structure; 45. second air pipe; 46. valve; 47. mesh plate; 48. fixed pipe; 49. connecting pipe.

[0019] As shown in the figure, in order to clearly implement the structure of the embodiment of the present invention, specific structures and devices are marked in the figure, but this is only for illustrative purposes and is not intended to limit the present invention to the specific structure, device and environment. According to specific needs, ordinary technicians in this field can adjust or modify these devices and environments. DETAILED DESCRIPTION

[0020] The following is a detailed description of an extraction device for producing pyrimidine compounds and a method for using the same provided by the present invention in conjunction with the accompanying drawings and specific embodiments. At the same time, it is explained here that in order to make the embodiments more detailed, the following embodiments are the best and preferred embodiments, and those skilled in the art may also adopt other alternatives to implement some known technologies; and the accompanying drawings are only for a more specific description of the embodiments, and are not intended to specifically limit the present invention.

[0021] It should be noted that the references to "one embodiment", "embodiment", "exemplary embodiments", "some embodiments" and the like in the specification indicate that the embodiments described may include specific features, structures or characteristics, but not every embodiment may include the specific features, structures or characteristics. In addition, when a specific feature, structure or characteristic is described in conjunction with an embodiment, it should be within the knowledge of a person skilled in the art to implement such feature, structure or characteristic in conjunction with other embodiments (whether or not explicitly described).

[0022] In general, a term can be understood, at least in part, from its use in context. For example, depending, at least in part, on the context, the terms "one or several" as used herein can be used to describe any feature, structure, or characteristic in a singular sense, or can be used to describe a combination of features, structures, or characteristics in a plural sense. Additionally, the term "based on" can be understood as not necessarily intended to convey an exclusive set of factors, but can instead, depending, at least in part, on the context, allow for the presence of other factors that are not necessarily explicitly described.

[0023] It will be understood that the meanings of “on,” “over,” and “above” in the present invention should be interpreted in the broadest manner, so that “on” not only means “directly on” something, but also includes the meaning of being “on” something with intervening features or layers therebetween, and “on” or “over” not only means “on” or “above” something, but also includes the meaning of being “on” or “above” something with no intervening features or layers therebetween.

[0024] Additionally, spatially relative terms such as "under," "beneath," "lower," "over," "upper," and the like may be used herein for descriptive convenience to describe the relationship of one element or feature to another or several elements or features, as shown in the accompanying drawings. The spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the accompanying drawings. The device may be oriented in other ways, and the spatially relative descriptors used herein may be similarly interpreted accordingly.

[0025] like Figures 1 to 19As shown, an embodiment of the present invention provides an extraction device for producing pyrimidine compounds, including a first tank body 1 and a second tank body 2, a driving motor 3 is arranged at the top of the first tank body 1, a stirring drum 10 and a feeding drum 11 are arranged in the first tank body 1, the driving motor 3 is a prior art, and its rotation speed is set according to demand, a detachable driving rod 6 is installed at the output end of the driving motor 3, and a stirring blade 7 movable in the stirring drum 10 is fixedly connected to the side wall of the driving rod 6; a first air pipe 4 and a second air pipe 45 are fixedly connected to the first tank body 1 and the second tank body 2, respectively, and the first air pipe 4 and the second air pipe 45 are connected to an external temperature control device, so that the first tank body 1, the second tank body 2 and the external temperature control device form a heating channel through the first air pipe 4 and the second air pipe 45, and the temperature control device is a prior art, such as an air energy constant temperature device, and when working, hot air enters the second tank body 2 and the second tank body 2 in sequence through the second air pipe 45. The hot air flows through the first tank body 1 and is finally discharged through the first air pipe 4. The first tank body 1 and the second tank body 2 are heated when the hot air flows through. The first tank body 1 and the second tank body 2 may be provided with a prior art temperature sensing system. When the temperature in the first tank body 1 and the second tank body 2 exceeds a preset temperature value, the constant temperature device is automatically closed. It should be noted that the constant temperature device is not limited to an air-energy constant temperature device and may be replaced by other devices. The prior art will not be described in detail here. A plurality of static chambers 42 are provided in the second tank body 2. A residual liquid chamber 43 is provided at the bottom of each of the static chambers 42. A filter material structure 44 is installed between the static chamber 42 and the residual liquid chamber 43. The filter material structure 44 is a prior art and will not be described in detail. It also includes a conversion assembly installed between the plurality of static chambers 42. When the current static chamber 42 is filled with the mixed liquid, it is automatically closed, and at the same time, the next static chamber 42 is opened to collect the mixed liquid.

[0026] like Figure 2 , Figure 4 As shown, the conversion assembly includes a lower liquid hopper 12 and a fixed cylinder 19 fixedly connected to the bottom end of the lower material cylinder 11, and a plurality of downpipes 20 are fixedly connected to the outer peripheral side wall of the fixed cylinder 19, and the plurality of downpipes 20 are respectively connected to a plurality of static chambers 42, wherein the plurality of downpipes 20 are arranged around the fixed cylinder 19, and the plurality of downpipes 20 are close to the bottom end of the fixed cylinder 19, and the fixed end of the downpipe 20 and the fixed cylinder 19 is gradually inclined toward the other end; a fixed ring body 21 is rotatably connected in the fixed cylinder 19, and a through opening 25 is provided on the peripheral side wall of the fixed ring body 21, wherein the fixed ring body 21 and the fixed cylinder 19 have matching sizes, and when the through opening 25 on the fixed ring body 21 is aligned with the downpipe 20, the through opening 25 makes the downpipe 20 and the fixed cylinder 19 form a connected state, and at the same time the fixed ring body 21 closes the other downpipes 20, and the mixed liquid in the fixed cylinder 19 enters the downpipe 20 through the through opening 25.

[0027] like Fig.14 , Fig.15As shown, a pair of slide grooves 26 are provided in the fixed ring body 21, and the pair of slide grooves 26 are respectively located on opposite sides of the through opening 25, and a slide rod 28 is provided in the pair of slide grooves 26 for limiting sliding, and a first spring 27 is sleeved on the side walls of the pair of slide rods 28, and a pair of slide rods 28 are fixedly connected to a support rod 29 at one end facing the downpipe 20, and a support plate 30 is fixedly connected to the outer wall of the support rod 29, and first rollers 31 are fixedly connected to both ends of the support plate 30, and the support plate 30 is inclined, and there are arc structures 32 between the plurality of downpipes 20, and the plurality of downpipes 20 are fixedly connected to the first rollers 31. 0 are fixedly connected with a plurality of support frames 35, and push rods 33 and connecting ropes 37 are slidably connected in the plurality of support frames 35, the push rods 33 and connecting ropes 37 are fixed to each other, and one end of the push rods 33 away from the connecting rope 37 is rotatably connected with a second roller 34, and one end of the connecting rope 37 away from the push rods 33 is fixedly connected with a cone head 38, and a second spring 36 is sleeved between the push rods 33 and the support frames 35, and a floating plate 39 is fixedly connected to the bottom end of the cone head 38, wherein the support rods 29 and the support plates 30 are both inclined, and the second roller 34 is located at the topmost end of the support plates 30.

[0028] like Figures 14 to 18 As shown, the support plate 30 and other structures are located in the sewer pipe 20 in the initial state. As the mixed liquid gradually fills the static chamber 42, the floating plate 39 gradually floats up and drives the cone head 38 to gradually insert into the sewer pipe 20 for sealing. During this process, the connecting rope 37 gradually relaxes, so that the second spring 36 on the push rod 33 drives the push rod 33 to reset, and the second roller 34 at one end of the push rod 33 squeezes the support plate 30, so that the support plate 30 drives the slide bar 28 to move toward the fixed cylinder 19, so that the support plate 30 and other structures are separated from the sewer pipe 20; at the same time, the slide bar 28 squeezes the first spring 27 to a compressed state, and the slide bar 28 slides in the slide groove 26 to the deepest point, so that the slide bar 28 cannot continue to slide. Move toward the fixed cylinder 19; due to the integrated structure of the support rod 29 and the sliding rod 28, when the support plate 30 continues to be squeezed by the second roller 34, the second roller 34 on the push rod 33 rolls along the support plate 30 from the highest point to the lowest point. During this process, the support plate 30 and other structures are squeezed and slide into the next sewer pipe 20, and return to the initial position, thereby achieving the purpose of automatically closing the current static chamber 42 and automatically opening the next static chamber 42. Therefore, during the production process, there is no need to wait for the mixed liquid in the current static chamber 42 to be extracted, and the subsequent addition of the mixed liquid will not interfere with the previous work process, thereby effectively improving the production efficiency and achieving the purpose of sustainable production.

[0029] It should be noted that the buoyancy of the float 39 > the weight of the float 39 > the elastic force of the second spring 36 > the elastic force of the first spring 27; the function of the several support frames 35 is to support the connecting rope 37 and the support push rod 33 so that the connecting rope 37 and the push rod 33 are both located in the center position of the sewer pipe 20.

[0030] like Fig.18 As shown, a plurality of lower water grooves 40 are provided on the top wall of the floating plate 39, and the plurality of lower water grooves 40 are arranged in a ring with the cone head 38 as the center. A plurality of lower water pipes 20 are fixedly connected with a baffle 41 at one end away from the fixed cylinder 19, and the cone head 38 is located below the baffle 41. By providing a plurality of lower water grooves 40 arranged in a ring on the top wall of the floating plate 39, when the mixed liquid flows onto the floating plate 39 through the cone head 38, the lower water grooves 40 on the floating plate 39 disperse the mixed liquid to the surroundings, which is beneficial for the mixed liquid to be mixed again before standing.

[0031] like Fig.16 As shown, the side wall of the driving rod 6 is provided with a plurality of planes 22, and a pair of slide bars 28 are fixedly connected with a fixing frame 23 toward one end of the driving rod 6, and the connection between the fixing frame 23 and the slide bar 28 is a curved structure 24, and the fixing frame 23 is in contact with the plurality of planes 22, wherein there are three planes 22, which are arranged in a U-shape at one end of the side wall of the driving rod 6 close to the mounting seat 5, and the fixing frame 23 is a U-shaped structure. By default, the fixing frame 23 of the U-shaped structure is stuck on the driving rod 6, and the fixing frame 23 of the U-shaped structure is in contact with the three planes 22, so that the fixing frame 23 cannot rotate, thereby further preventing the fixing ring body 21 from rotating in the fixing tube 19 and causing the support rod 29 to detach from the sewer pipe 20, and thus The stability of the conversion assembly is improved; when the slide rod 28 is squeezed and moved toward the position of the fixed tube 19, the slide rod 28 drives the fixed frame 23 to move. Since the diameter of the curved structure 24 is larger than the diameter of the fixed frame 23, when the curved structure 24 at the connection between the slide rod 28 and the fixed frame 23 moves to the side wall around the driving rod 6, the fixed frame 23 is separated from the contact with the plane 22, so that the fixed ring body 21 can rotate in the fixed tube 19. Therefore, when the support rod 29 and the support plate 30 are located in the sewer pipe 20, the fixed frame 23 is stuck on the driving rod 6. When the support rod 29 and the support plate 30 are separated from the sewer pipe 20, the fixed frame 23 is separated from the driving rod 6, thereby achieving the purpose of automatic adjustment of clamping or loosening.

[0032] like Figure 7 As shown, the bottom end of the fixed ring body 21 is fixedly connected to a fixed tube 48, the bottom end of the fixed cylinder 19 is fixedly connected to a mounting seat 5, the fixed tube 48 is inserted into the mounting seat 5, and a bearing is installed between the mounting seat 5 and the fixed tube 48. The bearing can be a sealed bearing in the prior art and will not be described in detail. By setting a plurality of down pipes 20, since the inner end of the down pipe 20 is fixed to the fixed cylinder 19, the outer end of the down pipe 20 is fixed to the baffle 41, and the driving rod 6 is rotatably connected to the bottom of the mixing drum 10 and the bottom of the fixed cylinder 19 respectively through the above-mentioned structure, the plurality of down pipes 20 can play a role in supporting the driving rod 6 and improve the stability of the driving rod 6.

[0033] like Figures 9 to 19As shown, the top and bottom ends of the lower barrel 11 are fixedly connected to a fixed plate 15, a spiral plate 16 and a plurality of staggered baffles 18 are fixedly connected inside the lower barrel 11, the plurality of baffles 18 penetrate the spiral plate 16 and the fixed plate 15, and a mixing channel 17 is formed between the plurality of baffles 18; a guide barrel 13 is fixedly connected between the mixing barrel 10 and the lower barrel 11, a plurality of lower liquid ports 14 connected to the guide barrel 13 are provided on the inner wall of the lower barrel 11, a connecting pipe 49 is installed between the mixing barrel 10 and the guide barrel 13, a valve 46 is installed on the connecting pipe 49, and the valve 46 is a prior art structure, so it will not be described in detail; when the driving rod 6 rotates, the stirring blade 7 is driven to rotate in the mixing barrel 10 to mix the original solution and the extractant into a mixed solution, and the mixed solution It then flows into the discharge barrel 11. During this process, the multiple staggered baffles 18 on the spiral plate 16 block the mixed liquid, allowing the mixed liquid to flow through the curved mixing channel 17, which not only prolongs the residence time of the mixed liquid in the channel, but also the curved mixing channel 17 allows the mixed liquid to repeatedly collide and mix in the curved mixing channel 17, thereby helping to improve the mixing effect of the mixed liquid; in addition, since the baffles 18 are hollow, when the hot air enters the second tank body 2 and the first tank body 1 through the second air pipe 45 and is then discharged through the first air pipe 4, during this process, the hot air will flow through the inside of the baffles 18, thereby improving the contact between the mixed liquid and the heat, which is beneficial to improving the constant temperature uniformity of the mixed liquid and improving the efficiency of the subsequent extraction process.

[0034] like Figure 2 , Figure 8 As shown, the driving rod 6 passes through the mixing drum 10, the discharge drum 11 and the fixed drum 19 in sequence, and the bottom end of the driving rod 6 is fixedly connected with the fan blade 8 located below the fixed drum 19. The driving rod 6 and the mixing drum 10 are rotatably connected through a sealed bearing. By arranging the fan blade 8 at the bottom end of the driving rod 6, hot air enters the second tank body 2 through the second air pipe 45, and the driving rod 6 drives the fan blade 8 to rotate, so that the hot air entering the second tank body 2 is transported to the first tank body 1, which is beneficial to the flow of hot air and improves uniformity.

[0035] like Figure 7 , Figure 8As shown, the side wall of the driving rod 6 is fixedly connected with a scraper 9, and the scraper 9 is in contact with a mesh plate 47 detachably installed in the fixed cylinder 19, wherein the mesh plate 47 is a prior art, and the aperture is selected according to the needs in actual use, and there are at least two scrapers 9, and the scrapers 9 are evenly distributed around the driving rod 6. When working, the mixed liquid stirred by the mixing drum 10 sequentially passes through the lower barrel 11 and the lower liquid hopper 12 into the fixed cylinder 19. During the stirring process of the mixing drum 10 and the flow of the lower barrel 11, if the mixed liquid generates foam, these foams will be When passing through the fixed cylinder 19 and entering the sewer pipe 20, it is blocked by the mesh plate 47, while the liquid can flow into the sewer pipe 20 through the mesh plate 47, effectively preventing bubbles from entering the static chamber 42 and affecting the mass transfer process and reducing the extraction efficiency; when the driving rod 6 rotates, the scraper 9 will be driven to rotate together. Since the scraper 9 is close to the mesh plate 47, the scraper 9 can scrape the foam on the mesh plate 47, which can not only prevent the foam from further accumulating and affecting the conveying efficiency, but also make the broken foam become liquid and continue to flow into the fixed cylinder 19 through the mesh plate 47, thereby reducing material waste.

[0036] The present application also provides a method for using an extraction device for producing pyrimidine compounds, comprising the following steps: S1, firstly, the original solution containing the target substance and the extractant are added into the stirring drum 10, then the driving motor 3 is started for stirring, and the external constant temperature device is started to transport hot air into the tank through the second air pipe 45; S2. After the required stirring time is reached, the valve 46 is opened to allow the mixed liquid in the mixing cylinder 10 to enter the lower cylinder 11 for re-mixing and constant temperature heating. The mixed liquid in the lower cylinder 11 enters the fixed cylinder 19 through the lower liquid hopper 12; S3, the mixed liquid in the fixed cylinder 19 enters the static chamber 42 through the conversion component for static treatment, and the current static chamber 42 is automatically closed after the liquid is filled, and the next static chamber 42 is opened at the same time; S4, the mixed liquid in the static chamber 42 is processed by the filter material structure 44, the filter material structure 44 blocks and filters the extraction phase in the mixed liquid, and the raffinate passes through the filter material structure 44 and enters the residual liquid chamber 43.

[0037] The working principle of the technical solution provided by the present invention is as follows: when in use, the mixed liquid after mixing in the mixing drum 10 flows into the discharge drum 11. During this process, the multiple staggered baffles 18 on the spiral plate 16 block the mixed liquid, so that the mixed liquid flows through the curved mixing channel 17, which not only prolongs the residence time of the mixed liquid in the channel, but also the curved mixing channel 17 allows the mixed liquid to repeatedly collide and mix in the curved mixing channel 17, thereby helping to improve the mixing effect of the mixed liquid; in addition, since the baffle 18 is hollow, when hot air enters the second tank body 2 and the first tank body 1 through the second air pipe 45 and is then discharged through the first air pipe 4, during this process, the hot air will flow through the inside of the baffle 18, thereby improving the contact between the mixed liquid and heat, which is beneficial to improving the constant temperature uniformity of the mixed liquid and improving the efficiency of the subsequent extraction process.

[0038] When the mixed liquid passes through the lower barrel 11 and the lower liquid hopper 12 in turn and enters the fixed barrel 19, during the stirring process of the stirring barrel 10 and the flow process of the lower barrel 11, if the mixed liquid generates foam, these foams will be blocked by the mesh plate 47 when the mixed liquid passes through the fixed barrel 19 and enters the downpipe 20, and the liquid can flow into the downpipe 20 through the mesh plate 47, effectively preventing the bubbles from entering the static chamber 42 and affecting the mass transfer process and reducing the extraction efficiency; when the driving rod 6 rotates, it will drive the scraper 9 to rotate together. Since the scraper 9 is close to the mesh plate 47, the scraper 9 can scrape the foam on the mesh plate 47, which can not only prevent the foam from further accumulating and affecting the conveying efficiency, but also make the broken foam become liquid and continue to flow into the fixed barrel 19 through the mesh plate 47, thereby reducing material waste.

[0039] As the mixed liquid gradually fills the static chamber 42, the floating plate 39 gradually floats up and drives the cone head 38 to gradually insert into the sewer pipe 20 for sealing. During this process, the connecting rope 37 gradually relaxes, so that the second spring 36 on the push rod 33 drives the push rod 33 to reset, and the second roller 34 at one end of the push rod 33 squeezes the support plate 30, so that the support plate 30 drives the slide bar 28 to move toward the fixed cylinder 19, so that the support plate 30 and other structures are separated from the sewer pipe 20; at the same time, the slide bar 28 squeezes the first spring 27 to a compressed state, and the slide bar 28 slides The limited sliding in the groove 26 reaches the deepest point, so that the sliding rod 28 cannot continue to move toward the fixed tube 19; due to the integrated structure of the support rod 29 and the sliding rod 28, when the support plate 30 continues to be squeezed by the second roller 34, the second roller 34 on the push rod 33 rolls along the support plate 30 from the highest point to the lowest point. In this process, the support plate 30 and other structures are squeezed and slide into the next sewer pipe 20 and return to the initial position, thereby achieving the purpose of automatically closing the current static chamber 42 and automatically opening the next static chamber 42.

[0040] In actual use, each independent static chamber 42 and the stirring drum 10 are connected by an external pipeline. After each layering, the extraction phase is remixed with a new extraction liquid for the next extraction, so as to improve the purity of the pyrimidine compound.

[0041] The present invention covers any substitution, modification, equivalent method and scheme made on the essence and scope of the present invention. In order to make the public have a thorough understanding of the present invention, specific details are described in detail in the following preferred embodiments of the present invention, but those skilled in the art can fully understand the present invention without the description of these details. In addition, in order to avoid unnecessary confusion about the essence of the present invention, well-known methods, processes, procedures, components and circuits are not described in detail.

[0042] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. An extraction device for producing pyrimidine compounds, characterized in that: It comprises a first tank body and a second tank body, wherein a driving motor is arranged at the top of the first tank body, a mixing drum and a feeding drum are arranged in the first tank body, a detachable driving rod is installed at the output end of the driving motor, and a stirring blade movable in the mixing drum is fixedly connected to the peripheral side wall of the driving rod; The first tank body and the second tank body are respectively fixedly connected with a first air pipe and a second air pipe, and the first air pipe and the second air pipe are both connected to an external temperature control device, so that the first tank body, the second tank body and the external temperature control device form a heating channel through the first air pipe and the second air pipe; a plurality of static chambers are arranged in the second tank body, and a residual liquid chamber is arranged at the bottom of the plurality of static chambers, and a filter material structure is installed between the static chamber and the residual liquid chamber; It also includes a conversion assembly installed between the plurality of static chambers, which automatically closes when the current static chamber is filled with the mixed liquid, and simultaneously opens the next static chamber to collect the mixed liquid; The conversion assembly includes a lower liquid hopper and a fixed cylinder fixedly connected to the bottom end of the lower material cylinder, a plurality of lower water pipes are fixedly connected to the outer peripheral side wall of the fixed cylinder, and the plurality of lower water pipes are respectively connected to a plurality of static chambers, a fixed ring body is rotatably connected in the fixed cylinder, and a through opening is opened on the peripheral side wall of the fixed ring body; The bottom end of the fixed ring body is fixedly connected to a fixed pipe, the bottom end of the fixed cylinder is fixedly connected to a mounting seat, the fixed pipe is inserted into the mounting seat, and a bearing is installed between the mounting seat and the fixed pipe; A pair of slide grooves are opened in the fixed ring body, and the pair of slide grooves are respectively located on two opposite sides of the through opening, and there are slide rods in the pair of slide grooves for limiting sliding, and the side walls of the pair of slide rods are sleeved with first springs, and one end of the pair of slide rods facing the sewer pipe is commonly fixedly connected with a support rod, and a support plate is fixedly connected to the outer wall of the support rod, and first rollers are fixedly connected to both ends of the support plate, and the support plate is inclined, and there are arc structures between several of the sewer pipes.

2. The extraction device for producing pyrimidine compounds according to claim 1, characterized in that: Several support frames are fixedly connected in the several sewer pipes, and push rods and connecting ropes are slidably connected in the several support frames respectively. The push rods and the connecting ropes are fixed to each other, and one end of the push rod away from the connecting rope is rotatably connected to a second roller, and one end of the connecting rope away from the push rod is fixedly connected to a cone head, and a second spring is sleeved between the push rod and the support frame.

3. The extraction device for producing pyrimidine compounds according to claim 2, characterized in that: The bottom end of the cone head is fixedly connected to a floating plate, the top wall of the floating plate is provided with a plurality of lower water troughs, the plurality of lower water troughs are arranged in a ring with the cone head as the center, the ends of the plurality of lower water pipes away from the fixed cylinder are commonly fixedly connected to a baffle cover, and the cone head is located below the baffle cover.

4. The extraction device for producing pyrimidine compounds according to claim 3, characterized in that: The side wall of the driving rod is provided with a plurality of planes, and a pair of sliding rods are fixedly connected with a fixing frame at one end facing the driving rod. The connection between the fixing frame and the sliding rod is a curved structure, and the fixing frame is in contact with the plurality of planes.

5. The extraction device for producing pyrimidine compounds according to claim 4, characterized in that: The top and bottom ends of the lower barrel are fixedly connected to fixed plates, a spiral plate and a plurality of staggered baffle tubes are fixedly connected inside the lower barrel, the plurality of baffle tubes penetrate the spiral plate and the fixed plate, and a mixing channel is formed between the plurality of baffle tubes; A guide cylinder is fixedly connected between the mixing cylinder and the lower material cylinder. The inner wall of the lower material cylinder is provided with a plurality of lower liquid ports connected with the guide cylinder. A connecting pipe is installed between the mixing cylinder and the guide cylinder, and a valve is installed on the connecting pipe.

6. The extraction device for producing pyrimidine compounds according to claim 5, characterized in that: The driving rod passes through the mixing drum, the feeding drum and the fixed drum in sequence, the bottom end of the driving rod is fixedly connected with a fan blade located below the fixed drum, and the driving rod and the mixing drum are rotatably connected via a sealed bearing.

7. The extraction device for producing pyrimidine compounds according to claim 6, characterized in that: A scraper is fixedly connected to the peripheral side wall of the driving rod, and the scraper is in contact with a mesh plate that is detachably installed in the fixed cylinder.

8. The method for using the extraction device for producing pyrimidine compounds according to any one of claims 1 to 7, characterized in that: The following steps are involved: S1. First, add the original solution containing the target substance and the extractant into the stirring drum, then start the driving motor for stirring, and start the external constant temperature equipment to transport hot air into the tank through the second air pipe; S2. After the required stirring time is reached, the valve is opened to allow the mixed liquid in the mixing cylinder to enter the lower cylinder for re-mixing and constant temperature heating. The mixed liquid in the lower cylinder enters the fixed cylinder through the lower liquid hopper; S3, the mixed liquid in the fixed cylinder enters the static chamber through the conversion component for static treatment, and the current static chamber is automatically closed after the liquid is filled, and the next static chamber is opened at the same time; S4. The mixed liquid in the static chamber is processed by the filter material structure, the filter material structure blocks and filters the extraction phase in the mixed liquid, and the raffinate enters the raffinate chamber through the filter material structure.

Images