Heterogeneous substance mixing kit

Abstract

The present invention relates to a kit for mixing heterogeneous substances, the kit comprising: a first container member including a first filling space for filling a first substance, a first shielding unit for sealing an inlet of the first filling space, and a perforating member for perforating the first filling space and the first shielding unit; the perforating member protrudes from the inner bottom of the first filling space by a predetermined length in the axial direction; and a second container member including a second filling space filled with a second substance, the second container member being inserted into the first container member through the inlet of the first container member in use; the second container member includes: a second shielding unit that shields one end of the second filling space and can be opened by the perforating member when the first container member and the second container member are coupled; the third shielding unit shields the other end of the second filling space and can open the other end of the second filling space when necessary.

Description

Technical Field

[0001] The invention relates to a heterogeneous substance mixing kit, which can safely and separately store a plurality of different substances to be mixed with each other for use, and when in use, the plurality of substances stored separately can be simply mixed for use. Background Art

[0002] As is well known, various chemical or biochemical test methods are used to measure biological indicators related to specific diseases, general health conditions or infections, etc. These chemical or biochemical test methods are usually performed through multi-step chemical reactions and physical operations using various reagents and instruments.

[0003] For example, the detection of biochemical substances such as occult blood, specific chemicals or proteins contained in feces or mucus requires multiple steps of physical operations, including collecting the sample, placing the collected sample in a certain container and reacting it with one or more reagents, and then dispensing the reacted sample from the container before applying it to a test or reading device.

[0004] When using a sample to be analyzed, such as blood, a detection antibody labeled with a fluorescent substance or the like, or whole blood, a solution (reagent) to which a reagent for lysing red blood cells is added is mixed and reacted in a quantitative ratio, and then the analysis is performed by loading the sample onto a sample pad of an analysis device or a cartridge.

[0005] As described above, solutions used for chemical or biochemical tests, etc., often use a mixed solution formed by mixing a plurality of different substances. However, if a plurality of substances to be mixed for use in disease diagnosis, etc. are mixed in advance, they are easy to deteriorate due to easy evaporation or moisture, in which case accurate diagnosis or analysis is difficult, and therefore they must be stored in separate containers. In addition, during the test, the plurality of substances stored separately are measured and mixed one by one using an instrument such as a pipette, or by opening containers storing heterogeneous substances to be mixed according to a predetermined mixing ratio, pouring them into one container and mixing them, and then using a pipette for subpackaging.

[0006] Therefore, not only is it difficult to store various substances used as reagents, but there is also a problem that diagnosis or analysis work is also quite complicated.

[0007] On the other hand, existing document 1 discloses a dropper having a tip portion causing capillary action at the lower end of an inlet tube containing boric acid latex balls, thereby enabling mixing and dispensing of blood, boric acid latex balls and a buffer solution through a dropper.

[0008] However, the problem with the prior art document 1 is that, due to the nature of the dropper, the front end of the tip portion is opened and therefore must be managed in a separate package, and there is a problem that it cannot be used when both substances to be mixed are liquids. Summary of the invention

[0009] Problem that the invention aims to solve

[0010] The present invention is developed in view of the existing problems as described above, and its purpose is to provide a heterogeneous substance mixing kit. For example, the heterogeneous substance mixing kit can safely and separately store a variety of different substances used as diagnostic or analytical reagents, etc., and the separately stored heterogeneous substances can be easily mixed for use when in use.

[0011] However, the purpose of the present invention is not limited to the above-mentioned purpose, and other purposes not mentioned can be clearly understood by those skilled in the art through the following description.

[0012] Means used to solve problems

[0013] In order to solve the above problems, a heterogeneous substance mixing kit according to the present invention includes: a first container component, including a first filling space, a first shielding unit and a perforating component, the first filling space is filled with the first substance, the first shielding unit seals the entrance of the first filling space, and the perforating component protrudes axially from the inner bottom of the first filling space by a predetermined length; and a second container component, including a second filling space for filling with the second substance, which is inserted into the interior of the first container component through the entrance of the first container component when in use; the second container component includes a second shielding unit and a third shielding unit, the second shielding unit shields one end of the second filling space and can be opened by the perforating component when the first container component and the second container component are combined, and the third shielding unit shields the other end of the second filling space and can open the other end of the second filling space when needed.

[0014] According to one embodiment of the present invention, the second shielding unit can be composed of an intercepting shielding member, which is integrally formed with the second container member and has an annular intercepting line corresponding to the inner circumferential surface of the second filling space at the edge so as to be cut from the second container member by the perforating member when the first container member and the second container member are combined.

[0015] According to an embodiment of the present invention, the intercepting shielding member may have a shape in which an edge portion is inclined and recessed into the inner side of the second filling space.

[0016] According to an embodiment of the present invention, the second shielding unit may be composed of a second sealing membrane, which is crimped to one end of the second container member, and the perforating member can penetrate the second sealing membrane when the first container member and the second container member are combined.

[0017] According to an embodiment of the present invention, the punching member may have a +-shaped, Y-shaped or T-shaped cross section.

[0018] According to an embodiment of the present invention, the third shielding unit may be a third sealing film in the form of a peelable sticker crimped or attached to the upper end of the second container member, or a plug switchably coupled to the upper end of the second container member.

[0019] Effects of the Invention

[0020] According to the heterogeneous substance mixing kit of the present invention as described above, the first substance and the second substance to be mixed can be stored respectively in the first container member and the second container member combined with each other, so that a plurality of different substances to be mixed and used in chemical or biochemical tests, etc. can be safely stored in a separated state.

[0021] In addition, during testing or analysis, multiple substances stored separately can be easily mixed simply by combining the second container member with the first container member, and the mixed liquid can be easily taken out and packaged using a pipette or the like by opening the stopper provided on the second container member.

[0022] Therefore, it is not necessary to use different containers or instruments to store and mix a plurality of substances to be mixed for use in diagnosis or analysis.

[0023] In addition, the plurality of substances to be mixed can be stored in the first container member and the second container member in a sealed state respectively. Therefore, not only when the plurality of substances are liquids and solids, but also when the plurality of substances are liquids and liquids, they can be safely stored and mixed, and there is the advantage of being able to store and mix heterogeneous substances regardless of the sampling volume. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is an exploded perspective view of the heterogeneous substance mixing kit according to the present invention.

[0025] Figure 2 Detailed description of the invention The figure is an exploded sectional view of a heterogeneous substance mixing kit according to the present invention.

[0026] Figure 3 It is a bottom view of the second container member of the heterogeneous substance mixing kit according to the present invention.

[0027] Figure 4 Parts (a) and (b) are cross-sectional views showing the combined state of the heterogeneous substance mixing kit according to the present invention.

[0028] Figure 5 The present invention is a perspective view showing a method of using the heterogeneous substance mixing kit according to the present invention.

[0029] Figure 6The present invention is a partially cut-away side view showing another embodiment of the third shielding unit of the heterogeneous substance mixing kit according to the present invention.

[0030] Figure 7 It is an exploded perspective view showing another embodiment of the second shielding unit of the heterogeneous substance mixing kit according to the present invention.

[0031] Figure 8 To illustrate the application Figure 7 FIG. 2 is a cross-sectional view of a combined state of the heterogeneous substance mixing kit of the present invention, showing another embodiment of the second shielding unit.

[0032] Fig. 9 For along Figure 8 A cross-sectional view taken along line IX-IX.

[0033] Description of Reference Numerals

[0034] 10: First container component

[0035] 11: Main body

[0036] 12: First filling space

[0037] 14, 24a: The first water-proof protrusion

[0038] 15: Perforated components

[0039] 16: Rib

[0040] 17: Support

[0041] 18: First sealing film

[0042] 20: Second container component

[0043] 21: Main body

[0044] 22: Second filling space

[0045] 24b, 33: Second water-proof protrusion

[0046] 25: Second sealing film

[0047] 26: Intercepting shielding components

[0048] 27: Intercept line

[0049] 27a: Cutting guide groove

[0050] 28: Inclined part

[0051] 29: Depression

[0052] 30: Stopper

[0053] 31: Shielding

[0054] 32: Insertion

[0055] 34: Switch guide

[0056] 40: Connecting piece

[0057] 50: The third sealing film

[0058] L1: First Substance

[0059] L2: Secondary Matter DETAILED DESCRIPTION

[0060] The specific features, other advantages and methods of achieving them of the present invention can be clarified by the accompanying drawings and the embodiments described in detail below. However, the present invention is not limited to the embodiments described below, and can be implemented in various different forms. This embodiment is only used to fully disclose the present invention so that those skilled in the art can fully understand the scope of the invention. The scope of the present invention is determined by the claims of the present invention. Throughout the specification, the same reference numerals refer to the same components.

[0061] In an embodiment of the present invention, the "first substance" and / or the "second substance" may be a liquid or solid reaction reagent, specifically, may be silica particles, proteins, amino acids, nucleic acids, lipids, carbohydrates, metabolites, reagents used as carriers, antibodies for selectively separating proteins, detection agents, blockers, optical signal enhancers, optical signal quenchers or other reagents, but are not limited thereto.

[0062] Hereinafter, a heterogeneous substance mixing kit according to an embodiment of the present invention will be described with reference to the accompanying drawings.

[0063] Reference Figures 1 to 4 , the heterogeneous substance mixing kit 1 according to the present invention basically includes a first container member 10 and a second container member 20 inserted into the first container member 10 .

[0064] The first container member 10 may be filled with a first substance L1 in a sealed state for storage. The first container member 10 may include a body 11 having a tube shape having a first filling space 12 therein and a perforated member 15 capable of opening a second shielding unit of the second container member 20 described below when combined with the second container member 20.

[0065] The main body 11 may be in the form of a long cylindrical tube for easy holding and dispensing, and one end (upper end) of the main body 11 is open to serve as an inlet 12a of the first filling space 12. After the first substance L1 is filled, the inlet 12a of the main body 11 is closed by the first shielding unit so that the first substance L1 filled inside can be safely sealed.

[0066] The first shielding unit can be implemented in various forms. For example, the first shielding unit can be composed of a conventional plug (not shown in the figure), or as shown in the figure, can be composed of a first sealing film 18 crimped to one end of the main body 11. Therefore, a flange 13 can be provided outwardly at the end of the inlet 12a side of the main body 11 so as to stably attach the first sealing film 18.

[0067] When the first container member 10 and the second container member 20 are combined, the first sealing film 18 can be torn by the second container member 20, or can also be in the form of a sticker that can be peeled off from the first container member 10 before the two are combined. Any form can be adopted. The first substance L1 can be a liquid or a solid such as particles. In this embodiment, the case of a liquid is taken as an example for description.

[0068] Preferably, an annular first water-proofing protrusion 14, 24a is preferably provided at least one place on the inner circumference upper side of the main body 11 of the first container member 10 or the outer circumference of the second container member 20. Preferably, for more reliable water tightness, the first water-proofing protrusion can be provided on the inner circumference of the first container member 10 and the outer circumference of the second container member 20, or two or more first water-proofing protrusions can be arranged at intervals in the axial direction. As described below, the above-mentioned first water-proofing protrusions 14, 24a can prevent the mixed solution from leaking when the first substance L1 and the second substance L2 are mixed in the first filling space 12 by shaking after the first container member 10 and the second container member 20 are combined. On the other hand, an O-ring can be provided on the outer circumference of the second container member 20 instead of the first water-proofing protrusions 14, 24a.

[0069] The perforating member 15 and the main body 11 may be formed integrally. The perforating member 15 may be formed to protrude a predetermined length in the axial direction from the inner bottom 12b of the first filling space 12. Specifically, the perforating member 15 is formed to have a length such that the front end of the perforating member 15 fully intrudes into the second shielding unit of the second container member 20 described below and enters the second filling space 22 when the first container member 10 and the second container member 20 are fully combined.

[0070] Such a perforated member 15 may have various forms, but preferably has a structure that allows the second substance L2 filled in the second filling space 22 of the second container member 20 to easily flow into the first filling space 12 of the first container member 10 after the second shielding unit is opened. Figures 6 to 8 As shown, when the second shielding unit of the second container member 20 described below is composed of a perforated second sealing film 25, preferably, the perforating member 15 has a structure that is easy to tear the second sealing film 25 by the bonding force between the first container member 10 and the second container member 20 when the first container member 10 and the second container member 20 are combined. To this end, as shown in the figure, the perforating member 15 preferably has a +-shaped cross section formed radially by, for example, four ribs (ribs) 16, because, when having a +-shaped cross section instead of a straight cross section or a circular cross section, it is not only conducive to tearing the second sealing film 25, but also conducive to forming a gap between the second sealing film 25 and the perforating member 15 after perforation.

[0071] In addition, although not shown separately, the perforating member 15 may have a Y-shaped cross section or a T-shaped cross section. Similar to the above-mentioned +-shaped cross section, the above-mentioned cross-sectional shape is also conducive to tearing the second sealing film 25 and forming a gap between the second sealing film 25 and the perforating member 15 after perforation.

[0072] On the other hand, a support portion 17 may be provided at the other end (lower end) of the first container member 10 so that the first container member 10 coupled to the second container member 20 can be safely placed upright during dispensing using a pipette P or the like.

[0073] The second container member 20 has a second filling space 22, so that the second substance L2 to be mixed with the first substance L1 can be filled and stored in a sealed state. The second filling space 22 can be formed by penetrating the cylindrical main body 21 in the axial direction. The lower end opening 22b of the second filling space 22 (inserted into one side of the first container member) can be sealed by a second shielding unit, and the second shielding unit can be opened by a perforated member 15 when the first container member 10 and the second container member 20 are combined. In addition, the upper end opening 22a of the second filling space 22 can be sealed by a third shielding unit, and the third shielding unit can be opened when needed (when used). The upper end periphery of the main body 21 is provided with a flange 23 to stably contact and support the third shielding unit. Moreover, the second substance L2 can also be a solid such as a liquid or a granule. In this embodiment, as with the first substance L1, the case of a liquid is described as an example.

[0074] For example, the second shielding unit may be constituted by a cut shielding member 26 that is integrally constituted with the second container member 20 and can be cut from the second container member 20 by the punching member 15 when the first container member 10 and the second container member 20 are combined.

[0075] The interception shielding member 26 may be configured to have a disc shape integrally formed with the inner surface of the lower end opening 22b of the second filling space 22, and have an annular interception line 27 corresponding to the inner circumferential surface of the second filling space 22 at the edge. Due to the cutting induction groove 27a formed concavely from the surface of the interception shielding member 26, the interception line 27 has a very thin thickness compared with the thickness of the interception shielding member 26, so that it is easily torn and cut due to the force applied to the interception shielding member 26 by the perforating member 15 when the first container member 10 and the second container member 20 are combined. Preferably, the cutting induction groove 27a is formed on the side in contact with the perforating member 15.

[0076] The intercepting shielding member 26 may be configured in a flat plate shape, but preferably has a shape recessed into the inner side of the second filling space 22 so that it can be cut more easily when the first container member 10 and the second container member 20 are combined. To this end, the intercepting shielding member 26 is composed of an inclined portion 28, the edge of which is appropriately inclined toward the second filling space 22 side, and the intercepting shielding member 26 has a recessed portion 29 on the lower surface for the front end of the punching member 15 to be placed.

[0077] For example, the third shielding unit may be composed of a plug 30 capable of opening and closing the upper end opening 22a of the second container member 20. The plug 30 may include a disc-shaped shielding portion 31 and a cylindrical insertion portion 32, the shielding portion 31 being in contact with the flange 23 of the second container member 20, and the insertion portion 32 being formed protruding from the lower surface of the shielding portion 31 and inserted into the second filling space 22 through the upper end opening 22a of the second container member 20. The second water leakage prevention protrusion 33, 24b may be provided at least one of the outer periphery of the insertion portion 32 of the plug 30 or the upper inner periphery of the second filling space 22 of the second container member 20. The second water leakage prevention protrusion 33, 24b prevents the second substance L2 filled in the second filling space 22 from leaking during storage, and in order to more reliably prevent water leakage, it may be formed at the outer periphery of the insertion portion 32 and the inner periphery of the second filling space 22 at the same time.

[0078] In addition, a switch guide piece 34 may be provided on one side of the shielding portion 31 of the stopper 30 to easily open and close the stopper 30. The stopper 30 may be configured to be separated from the second container member 20, or, as shown in the figure, may also be configured to be integrally connected via a connecting piece 40.

[0079] On the other hand, Figure 6As shown, the third shielding unit is used in a state of being crimped or attached to the upper end of the second container member 20, that is, the third shielding unit can be composed of a third sealing film 50 in the form of a sticker that can be peeled off from the second container member 20 after the first container member 10 and the second container member 20 are combined with each other.

[0080] Combination Figure 5 The method of using the heterogeneous substance mixing kit 1 of the present invention as described above will be described.

[0081] First, after peeling off and removing the first sealing film 18 that seals the inlet 12a of the first container member 10 or in a state where the first sealing film 18 is attached, the second container member 20 is inserted into the inlet 12a side of the opening of the first container member 10. Then, the second container member 20 is inserted into the first filling space 12 of the first container member 10 so that the two can be integrated. At this time, when the second container member 20 is inserted in a state where the first sealing film 18 is attached, the first sealing film 18 is torn by the first container member 20 so that the two can be integrated.

[0082] At the same time, the front end portion of the punching member 15 contacts and presses the lower surface of the intercepting shielding member 26 of the second container member 20, whereby the intercepting line 27 formed at the edge of the intercepting shielding member 26 is torn and cut from the second container member 20, thereby opening the lower end opening 22b of the second container member 20. Then, the first filling space 12 and the second filling space 22 are communicated with each other, so that the second substance L2 filled in the second filling space 22 of the second container member 20 can easily flow into the first filling space 12 of the first container member 10 through the opened lower end opening 22b of the second container member 20.

[0083] In this state, when the heterogeneous substance mixing kit 1 of the present invention combined with each other is appropriately shaken, the first substance L1 and the second substance L2 can be surely mixed in the first filling space 12 of the first container member 10 .

[0084] Next, the third shielding unit of the second container member 20 coupled to the first container member 10 is opened. At this time, if the third shielding unit is composed of a stopper 30, the stopper 30 is opened, and if the third shielding unit is composed of a third sealing film, it is peeled off and removed from the second container member 20. As a result, the upper end opening 22a of the second filling space 22 of the second container member 20 is opened, so that the first filling space 12 can be opened. In this state, a tool such as a pipette P can be inserted into the first filling space 12 through the opened second filling space 22 of the second container member 20 to extract and dispense the mixed solution.

[0085] Figures 7 to 9Another embodiment of the second shielding unit of the heterogeneous substance mixing kit 1 according to the present invention is shown.

[0086] This embodiment has a configuration in which the second shielding unit is crimped to the lower end of the second container member 20 and is composed of a second sealing film 25 through which the punching member 15 can penetrate when the first container member 10 and the second container member 20 are combined.

[0087] In the above-mentioned embodiment, Figure 8 As shown, when the first container component 10 and the second container component 20 are combined, the second sealing film 25 is torn and penetrated by the perforating member 15, so that the second filling space 22 is connected with the first filling space 12 through the access hole 25a drilled in the second sealing film 25, so that the second substance L2 can flow into the first filling space 12.

[0088] As long as one is a person of ordinary skill in the technical field to which the present invention belongs, it will be understood that without changing the technical concept or essential features of the present invention, it can also be easily transformed into other specific forms. Therefore, it should be understood that the embodiments described above are only illustrative in all aspects, but are not limited thereto. The scope of the present invention is indicated by the appended claims, rather than by the above detailed description, and all changes or deformations derived from the meaning, scope and equivalent concepts of the claims should be interpreted as included within the scope of the present invention.

Claims

1. A kit for mixing heterogeneous substances, characterized in that: include: The first container member comprises a first filling space, a first shielding unit and a perforating member, wherein the first filling space is filled with a first substance, the first shielding unit seals an entrance of the first filling space, and the perforating member protrudes from an inner bottom of the first filling space by a predetermined length in the axial direction; as well as A second container member, comprising a second filling space for filling with a second substance, which is inserted into the interior of the first container member through the inlet of the first container member when in use; The second container component includes a second shielding unit and a third shielding unit, the second shielding unit shields one end of the second filling space and can be opened through the perforated component when the first container component and the second container component are combined, and the third shielding unit shields the other end of the second filling space and can open the other end of the second filling space when needed.

2. The heterogeneous substance mixing kit according to claim 1, characterized in that: The second shielding unit is composed of a cutting shielding member, which is integrally formed with the second container member and has an annular cutting line corresponding to the inner circumferential surface of the second filling space at the edge so as to be cut from the second container member by the punching member when the first container member and the second container member are combined.

3. The heterogeneous substance mixing kit according to claim 2, characterized in that: The cutting shielding member has a shape in which an edge portion is arranged obliquely and is recessed into the inner side of the second filling space.

4. The heterogeneous substance mixing kit according to claim 1, characterized in that: The second shielding unit is composed of a second sealing film which is pressed against one end of the second container member, and the punching member can penetrate the second sealing film when the first container member and the second container member are combined.

5. The heterogeneous substance mixing kit according to claim 2, characterized in that: The perforated member has a +-shaped, Y-shaped or T-shaped cross section.

6. The heterogeneous substance mixing kit according to any one of claims 1 to 5, characterized in that: The third shielding unit is a third sealing film in the form of a peelable sticker that is crimped or attached to the upper end of the second container component, or a plug that is switchably coupled to the upper end of the second container component.

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