Embryo operation oral aspiration device

Abstract

The invention relates to a mouth suction device for embryo operation. The mouth suction device comprises a mouth suction section at the front end, a connecting section at the middle end and a suction / discharge section at the rear end, the mouth suction section comprises a straight pipe and a filter, one end of the straight pipe is connected with one end of the filter, the connecting section comprises a hose, one end of the hose is connected with the other end of the filter, the suction / outlet section comprises a hard connecting pipe, one end of the hard connecting pipe is connected with the other end of the hose, and the other end of the hard connecting pipe is connected with a rubber plug. The center of the rubber plug is provided with an insertion hole into which a glass needle is inserted. The embryo operation oral suction device provided by the invention can effectively solve the problem that saliva flows into and gathers in the oral suction tube, and improves the efficiency and success rate of experimental operation.

Description

Technical Field

[0001] The invention belongs to the technical field of in vitro embryo research experiments and relates to an embryo manipulation mouth suction device. Background Art

[0002] In the process of in vitro embryo research on mammals, whether it is collecting naked eggs, fertilized eggs, or in the experimental operation of transferring, cleaning, and transplanting fertilized eggs, embryo manipulation is a necessary experimental technical link. At present, most operators use homemade straight-through mouth pipettes. Usually, scientific researchers must hold one end of the mouth pipette in their mouths and use their mouths to blow and inhale into the front end of the mouth pipette to control the transfer or cleaning of cells at the other end of the mouth pipette. Usually, in a complete cell experimental operation, scientific researchers must always hold the mouth pipette in their mouths. During the normal breathing of scientific researchers, saliva will flow into and accumulate in the mouth pipette, which will cause the airflow to be unstable and difficult to control during the experimental operation, and severely block the mouth pipette, thereby affecting the efficiency and success rate of the experimental operation. Summary of the invention

[0003] The present invention provides an embryo manipulation mouth suction device, which can effectively solve the problem of saliva inflow and accumulation in the mouth suction tube, and improve the efficiency and success rate of experimental operation.

[0004] The technical solution of the present invention to solve the above problems is:

[0005] The present invention provides an embryo manipulation oral suction device, which is special in that:

[0006] It consists of three parts: the front end mouth suction section, the middle end connection section, and the rear end suction / exhaust section;

[0007] The mouth suction section includes a straight tube and a filter, one end of the straight tube is connected to one end of the filter, and further, a saliva collecting port is provided in the middle of the straight tube, the saliva collecting port is connected to a saliva collector, and the saliva collector is a closed container.

[0008] The connecting section comprises a hose, one end of which is connected to the other end of the filter; the inlet / outlet section comprises a hard connecting tube, one end of which is connected to the other end of the hose, and the other end is connected to a rubber plug, an insertion hole is provided in the center of the rubber plug, and a glass needle is inserted into the insertion hole.

[0009] Furthermore, the straight tube is a circular tube or a triangular tube. When the straight tube is a triangular tube, the saliva collecting port is located on one side of the triangular tube, and when in use, the wall surface connected to the saliva collecting port serves as the bottom surface, and saliva flows from the inner walls on both sides to the bottom surface where the saliva collecting port is located, thereby ensuring effective collection of saliva.

[0010] Furthermore, a curved pipe is provided in the middle of the straight pipe, the straight pipes on both sides of the curved pipe are coaxially arranged, and the saliva collecting port is located at the lowest point of the curved pipe. When in use, the curved pipe is downward, the saliva collecting port is at the lowest point, and the saliva flows from the higher positions on both sides of the curved pipe to the saliva collecting port at the lowest point, thereby ensuring effective collection of the saliva.

[0011] Furthermore, an oblate duckbill structure is connected to one end of the straight tube away from the filter, and a blocking protrusion is provided on the outer side of the duckbill structure.

[0012] Furthermore, the thickness of the duckbill structure gradually decreases from the end portion toward the blocking protrusion.

[0013] Furthermore, the tail of the duckbill structure is inserted into the straight tube. The duckbill structure is made of silicone.

[0014] Furthermore, the filter is used to filter water vapor in the air flow, and includes an upper cover and a lower cover, which are connected by threads, and a cavity is formed inside the upper cover and the lower cover. A breathable filter material is provided in the cavity, and the breathable filter material includes a spunbond non-woven fabric layer and a meltblown non-woven fabric layer. The spunbond non-woven fabric is close to the upper cover, and the spunbond non-woven fabric has a waterproof function. The meltblown non-woven fabric is made of polypropylene material with high melt index fiber, and is an ultra-fine electrostatic fiber cloth that can effectively utilize static electricity to absorb virus dust and droplets.

[0015] Furthermore, connecting pipes are provided on the upper cover and the lower cover of the filter, the connecting pipe of the upper cover is connected to the straight pipe, and the connecting pipe of the lower cover is connected to the hose.

[0016] Furthermore, the saliva collector is connected to the middle saliva collecting port of the straight tube via threads, so that replacement is convenient.

[0017] Furthermore, a connecting end is provided at one end of the straight tube connection filter, and an outer diameter of the connecting end is smaller than an outer diameter of the straight tube.

[0018] Advantages of the present invention:

[0019] The embryo manipulation mouth suction device provided by the present invention has a simple overall structure, can effectively solve the problem of saliva inflow and accumulation in the mouth suction tube, and improves the efficiency and success rate of experimental operations. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a structural diagram of an embodiment of an embryo manipulation oral suction device;

[0021] Figure 2 It is a structural diagram of the duckbill structure;

[0022] Figure 3 It is a structural diagram of another embodiment of an embryo manipulation mouth suction device.

[0023] In the figure, 1. straight tube; 2. filter; 3. hose; 4. hard connecting tube; 5. rubber stopper; 6. glass needle; 7. duckbill structure; 8. blocking protrusion; 9. upper cover; 10. lower cover; 11. breathable filter material; 12. saliva collector. DETAILED DESCRIPTION

[0024] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the invention claimed for protection, but merely represents selected embodiments of the present invention.

[0025] See also Figure 1 and Figure 3 , an embryo manipulation mouth suction device, consists of three parts: a mouth suction section at the front end, a connecting section at the middle end, and a suction / exhaust section at the rear end.

[0026] The oral suction section includes a straight tube 1 and a filter 2, one end of the straight tube 1 is connected to one end of the filter 2, a saliva collection port is provided in the middle of the straight tube 1, and the saliva collection port is connected to a saliva collector 12, and the saliva collector 12 is a closed container. The connecting section includes a hose 3, which is a rubber hose. One end of the hose 3 is connected to the other end of the filter 2, and the suction / exhaust section includes a hard connecting tube 4, one end of the hard connecting tube 4 is connected to the other end of the hose 3, and the other end is connected to a rubber stopper 5, and an insertion hole is provided in the center of the rubber stopper 5, and a glass needle 6 is inserted into the insertion hole.

[0027] In the process of in vitro embryo research of mammals, scientific and technical personnel need to transfer eggs or embryonic cells (hereinafter referred to as "cells") between different culture media, clean them after IVF, transplant them in vivo, and other routine experimental operations. In the specific cell operation experiment, scientific and technical personnel must hold one end of the straight tube 1 in their mouths and use their mouths to blow / inhale air into the mouth pipette tube. The airflow passes through the straight tube 1, the filter 2, the hose 3, the hard connecting tube 4 and the glass needle 6 in sequence to control the entry and exit, transfer, cleaning or transplantation of cells at the other end of the mouth pipette. Usually, in a complete cell experimental operation process, scientific and technical personnel must always hold the mouth pipette in their mouths. During the normal breathing of scientific and technical personnel, saliva will flow in. The saliva collection port in the middle of the straight tube 1 is connected to a saliva collector 12. When in use, the saliva collector 12 faces downward, the mouth enters the saliva collector 12, and the water vapor in the airflow enters the filter 2, and the filter 2 filters the water vapor. In this way, saliva and water vapor will not block the mouth pipette, and the airflow is stable during the experimental operation, thereby improving the efficiency and success rate of the experimental operation.

[0028] As a preferred embodiment of the present invention, the saliva collector 12 includes a soft capsule. When the saliva collector 12 needs to be cleaned, the saliva collector 12 is removed from the saliva collection port and the capsule is squeezed with fingers to quickly discharge the saliva in the capsule.

[0029] As a preferred embodiment of the present invention, the straight tube 1 is a round tube, or the straight tube 1 is a triangular tube (with a triangular cross section). When the straight tube 1 is a triangular tube, the saliva collecting port is located on one side of the triangular tube. When in use, the wall surface connected to the saliva collecting port serves as the bottom surface, so that saliva flows from the inner walls on both sides to the bottom surface where the saliva collecting port is located, thereby ensuring effective collection of saliva.

[0030] As a preferred embodiment of the present invention, see Figure 3 The straight pipe 1 is provided with a curved pipe in the middle, and the straight pipes on both sides of the curved pipe are coaxially arranged, and the saliva collecting port is located at the lowest point of the curved pipe. When in use, the curved pipe is downward, and the saliva collecting port is at the lowest point, and the saliva flows from the higher positions on both sides of the curved pipe to the saliva collecting port at the lowest point, ensuring that the saliva is effectively collected.

[0031] As a preferred embodiment of the present invention, see Figure 1 and Figure 2 The end of the straight tube 1 away from the filter 2 is connected with an oblate duckbill structure 7, and a blocking protrusion 8 is provided on the outside of the duckbill structure 7. The duckbill structure 7 is made of silicone material, which is convenient for the operator to put in the mouth, and the oblate duckbill structure 7 will not rotate, which is convenient for operation. The blocking protrusion 8 is used for limiting to prevent the duckbill structure 7 from extending too far into the operator's mouth.

[0032] As a preferred embodiment of the present invention, see Figure 2 The thickness of the duckbill structure 7 gradually decreases from the end to the blocking protrusion 8, so the operator does not have to worry about the duckbill structure 7 slipping out of the mouth, and the operator can use both hands to perform other operations.

[0033] As a preferred embodiment of the present invention, the tail of the duckbill structure 7 is inserted into the straight tube 1 and is detachably connected to facilitate cleaning and replacement of the duckbill structure 7 .

[0034] As a preferred embodiment of the present invention, the filter 2 is used to filter water vapor in the airflow, and includes an upper cover 9 and a lower cover 10, which are connected by threads, and a cavity is formed inside the upper cover 9 and the lower cover 10, and a breathable filter material 11 is provided in the cavity, and the breathable filter material 11 includes a spunbond non-woven fabric layer and a meltblown non-woven fabric layer. The spunbond non-woven fabric is close to the upper cover, and the spunbond non-woven fabric has a waterproof function, while the meltblown non-woven fabric is made of a polypropylene material with a high melt index fiber, which is an ultra-fine electrostatic fiber cloth that can effectively use static electricity to absorb virus dust and droplets.

[0035] As a preferred embodiment of the present invention, see Figure 1 The upper cover 9 and the lower cover 10 of the filter 2 are provided with connecting pipes. The connecting pipe of the upper cover 9 is inserted into the end of the straight pipe 1, and the connecting pipe of the lower cover 10 is sleeved with the hose 3.

[0036] As a preferred embodiment of the present invention, the saliva collector 12 is detachably connected to the middle saliva collecting port of the straight tube 1 through threads, so as to facilitate cleaning of the saliva in the saliva collector 12 .

[0037] As a preferred embodiment of the present invention, the straight tube 1 is provided with a connection end at one end connected to the filter 2, and the outer diameter of the connection end is smaller than the outer diameter of the straight tube 1, so that the hose 3 can be sleeved on the connection end. The hose 3 is about 15-20cm long, 7mm in diameter, and 5mm in inner diameter, which can ensure stable airflow.

[0038] The straight tube 1 and the saliva collector 12 are made of PPSU material, which can withstand high temperature sterilization and can be reused. There is a small hole in the middle of the rubber stopper 5, which can stably support the glass needle when the glass needle is inserted and effectively seal it. The glass capillary is a conventional consumable product. The glass needle can be drawn under an alcohol lamp, and the inner diameter of the tip can be enough to inhale mouse or rat embryonic cells.

[0039] The above descriptions are merely embodiments of the present invention and are not intended to limit the protection scope of the present invention. Any equivalent structure or equivalent process transformation made using the contents of the present invention specification and drawings, or directly or indirectly applied in other related system fields, are also included in the protection scope of the present invention.

Claims

1. An embryo manipulation oral suction device, characterized in that: It consists of three parts: the front end mouth suction section, the middle end connection section, and the rear end suction / exhaust section; The oral suction section comprises a straight tube (1) and a filter (2), one end of the straight tube (1) is connected to one end of the filter (2), a saliva collection port is provided in the middle of the straight tube (1), and the saliva collection port is connected to a saliva collector (12), and the saliva collector (12) is a closed container; The connecting section comprises a hose (3), one end of the hose (3) being connected to the other end of the filter (2); The inhalation / exhalation section comprises a hard connecting tube (4), one end of which is connected to the other end of the hose (3), and the other end is connected to a rubber stopper (5), an insertion hole is provided at the center of the rubber stopper (5), and a glass needle (6) is inserted into the insertion hole.

2. The embryo manipulation oral suction device according to claim 1, characterized in that: The straight tube (1) is a circular tube or a triangular tube. When the straight tube (1) is a triangular tube, the saliva collection port is located on a side surface of the triangular tube.

3. The embryo manipulation oral suction device according to claim 1, characterized in that: A curved pipe is provided in the middle of the straight pipe (1), the straight pipes on both sides of the curved pipe are coaxially arranged, and the saliva collection port is located at the lowest point of the curved pipe.

4. An embryo manipulation oral suction device according to any one of claims 1 to 3, characterized in that: An oblate duckbill structure (7) is connected to one end of the straight tube (1) away from the filter (2), and a blocking protrusion (8) is provided on the outer side of the duckbill structure (7).

5. The embryo manipulation oral suction device according to claim 4, characterized in that: The thickness of the duckbill structure (7) gradually decreases from the end portion to the blocking protrusion (8).

6. The embryo manipulation oral suction device according to claim 5, characterized in that: The tail of the duckbill structure (7) is inserted into the straight tube (1); the duckbill structure (7) is made of silica gel.

7. The embryo manipulation oral suction device according to claim 6, characterized in that: The filter (2) is used to filter water vapor in an air flow, and comprises an upper cover (9) and a lower cover (10), wherein the upper cover (9) and the lower cover (10) are connected by threads, and a cavity is formed inside the upper cover (9) and the lower cover (10), and an air-permeable filter material (11) is arranged in the cavity, and the air-permeable filter material (11) comprises a spunbond non-woven fabric layer and a melt-blown non-woven fabric layer.

8. The embryo manipulation oral suction device according to claim 7, characterized in that: The upper cover (9) and the lower cover (10) of the filter (2) are provided with connecting pipes, the connecting pipe of the upper cover (9) is connected to the straight pipe (1), and the connecting pipe of the lower cover (10) is connected to the hose (3).

9. The embryo manipulation oral suction device according to claim 8, characterized in that: The saliva collector (12) is connected to the saliva collection port in the middle of the straight pipe (1) via threads.

10. The embryo manipulation oral suction device according to claim 9, characterized in that: The straight pipe (1) is provided with a connecting end at one end connected to the filter (2), and the outer diameter of the connecting end is smaller than the outer diameter of the straight pipe (1).

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