Pulse power supply method, pulse power supply device and radiation device

By real-time acquisition and modulation of the working parameters of the electron gun, the pulse level of the electron beam output of the electron gun is achieved, and the problem of collaborative work and precise control of multiple electron guns in complex electromagnetic environments is solved, meeting the multi-angle irradiation needs under ultra-high dose conditions, and saving costs.

CN119789296APending Publication Date: 2025-04-08NUCTECH CO LTD
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Patent Information

Application Number
CN202510072116.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-16
Publication Date
2025-04-08

AI Technical Summary

Technical Problem

In electronic linear accelerators, how to achieve the coordinated work and precise control of multiple electron guns in complex electromagnetic environments, especially the need for FLASH flash therapy multi-angle irradiation under ultra-high dose conditions.

Method used

By collecting the working parameters of the target electron gun in real time, using the pulse power supply method, the modulated pulse signals are sent to the electron gun at intervals, so as to achieve precise pulse level control of the electron beam output of the electron gun. At the same time, a "one to multiple" power supply solution is provided, and multiple electronic guns are alternately powered by one power supply power supply, realizing precise beam current control at the pulse level.

Benefits of technology

The pulse-level precise control of the electron beam output of the electron gun is achieved, which meets the multi-angle irradiation needs under ultra-high dose conditions, saves overall costs, and improves the stability and reliability of the radiation source output.

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Abstract

The invention provides a pulse power supply method for an electron gun, and the method comprises the steps: collecting at least one working parameter of a target electron gun in real time, and enabling the at least one working parameter to comprise the gun voltage and the gun current of the target electron gun; n pulse signals are transmitted to the target electron gun at intervals to supply power, any two adjacent pulse signals are transmitted at intervals, and N is an integer larger than or equal to 2; wherein at least one of the N pulse signals is obtained by modulation according to the at least one working parameter. The invention further provides a pulse power supply method for the multiple electron guns.
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Description

Technical Field

[0001] The present disclosure relates to the field of radiotherapy, ultra-high-dose radiation, flash radiotherapy, radiation inspection, electron gun power supply or other technical fields, and more specifically, to a pulse power supply method, a pulse power supply device and a radiation device. Background Art

[0002] The classic use of an electron linear accelerator is: after receiving a beam-out command, the accelerator generates two continuous and stable high-voltage pulses, one acting on a microwave source (klystron or magnetron) to generate microwaves, and the other acting on an electron gun to generate an electron beam. The microwave accelerates the electron beam in the accelerator tube and then hits the target to generate X-rays.

[0003] With the development of security inspection and medical industries, the requirements for the accuracy of electron beams generated by electron guns are getting higher and higher. In addition, in some scenarios, a single electron linear accelerator cannot meet the needs, such as the needs of CT inspection of aviation boxes and multi-angle irradiation of FLASH flash therapy under ultra-high dose conditions. Therefore, multiple electron linear accelerators are provided, which raises the problem of how to accurately control the coordinated work of multiple electron guns in a complex electromagnetic environment. Summary of the invention

[0004] In view of the above problems, the present disclosure provides a pulse power supply method, a pulse power supply device and a radiation device.

[0005] According to a first aspect of the present disclosure, a pulse power supply method for an electron gun is provided, comprising: acquiring at least one operating parameter of a target electron gun in real time, wherein the at least one operating parameter includes a gun voltage and a gun current of the target electron gun; transmitting N pulse signals to the target electron gun at intervals for power supply, wherein any two adjacent pulse signals are transmitted at intervals, and N is an integer greater than or equal to 2; wherein at least one of the N pulse signals is modulated according to the at least one operating parameter.

[0006] In some embodiments, at least one of the N pulse signals is modulated according to the gun voltage and the gun current, including: based on the gun voltage and the gun current, determining the pulse voltage and pulse width of the pulse signal to be transmitted according to a preset first mapping relationship.

[0007] In some embodiments, at least one of the N pulse signals is modulated according to the at least one operating parameter and further includes: for any two adjacent pulse signals, the latter pulse signal is modulated according to the at least one operating parameter collected after the previous pulse signal is transmitted to the target electron gun.

[0008] In some embodiments, for a target pulse signal that is not transmitted for the first time among the N pulse signals, it also includes: modulating the pulse voltage and pulse width of the target pulse signal according to the gun voltage and gun current, and the last actual dose; wherein the last actual dose includes the actual dose output by the radiation source to which the target electron gun belongs after the last pulse signal of the target pulse signal is transmitted.

[0009] In some embodiments, modulating the pulse voltage and pulse width of the target pulse signal includes: correcting the gun voltage and gun current according to a second mapping relationship between the gun voltage and gun current of the target electron gun when delivering the previous pulse signal and the previous actual dose; and determining the pulse voltage and pulse width of the target pulse signal according to the corrected gun voltage and gun current.

[0010] In some embodiments, the intermittently transmitting matching N pulse signals to the target electron gun includes: after transmitting M pulse signals, obtaining a first superimposed dose of the radiation source to which the target electron gun belongs, wherein the first superimposed dose includes the sum of actual doses output by the radiation source measured in response to the transmission of the M pulse signals, and M is less than or equal to N; in response to any one of the N pulse signals being transmitted, determining the number of subsequent pulse signals to be transmitted based on the difference between the first superimposed dose and the target dose.

[0011] In some embodiments, determining the number of pulse signals to be delivered based on the difference between the first superimposed dose and the target dose includes: when M is less than N and the first superimposed dose is less than the target dose, continuing to deliver the pulse signal to be delivered among the N pulse signals; when M is less than N and the first superimposed dose is greater than or equal to the target dose, stopping executing the pulse signal to be delivered among the N pulse signals; when M is equal to N and the first superimposed dose is less than the target dose, increasing and delivering a predetermined number of pulse signals to be delivered.

[0012] In some embodiments, the increasing and transmitting of a predetermined number of pulse signals to be transmitted includes: after transmitting S pulse signals, obtaining a second superimposed dose of the radiation source to which the target electron gun belongs, wherein the second superimposed dose includes the sum of actual doses output by the radiation source measured in response to the transmission of the S pulse signals, and M is an integer greater than or equal to 1; in response to any one of the predetermined number of pulse signals to be transmitted being transmitted, determining the number of subsequent pulse signals to be transmitted based on the difference between the sum of the first superimposed dose and the second superimposed dose and the target dose.

[0013] In some embodiments, the intermittently transmitting N matching pulse signals to the target electron gun includes: the interval between any two adjacent pulse signals is less than or equal to 1 millisecond.

[0014] Another aspect of an embodiment of the present disclosure provides a pulse power supply method for multiple electron guns, comprising: obtaining an order in which multiple radiation sources send multiple radiation beams to the same target portion, and a pulse sequence matching the electron gun in each radiation source, the pulse sequence comprising N pulse signals, where N is an integer greater than or equal to 2; based on a method as described in any of the above items, controlling a power supply to alternately deliver a matching pulse sequence to multiple electron guns in the multiple radiation sources in the order for power supply.

[0015] In some embodiments, the multiple electron guns correspond one by one to multiple power supply ports, and controlling the power supply to alternately deliver matching pulse sequences to the multiple electron guns in the multiple radiation sources in the order for power supply includes: controlling the power supply to alternately select the power supply ports corresponding to the electron guns in the order.

[0016] In some embodiments, obtaining a pulse sequence that matches the electron gun in each radiation source includes: allocating multiple target doses to the multiple radiation sources one by one according to radiation task information, wherein any two target doses are the same or different; and determining a pulse sequence that matches the electron gun therein according to the target dose of each radiation source.

[0017] In some embodiments, determining a pulse sequence that matches an electron gun therein according to a target dose of each ray source includes: determining a sub-dose corresponding to each of the N pulse signals according to the target dose of each ray source; wherein the target dose is obtained by superimposing the N sub-doses.

[0018] In some embodiments, the order of obtaining the order in which the multiple radiation sources send multiple radiation beams to the same target portion includes: obtaining the time when each radiation source sends the radiation beam, and the position at the corresponding time; wherein different radiation sources send radiation beams at different times, and the position of each radiation source is dynamically adjustable.

[0019] In some embodiments, the power supply is controlled to alternately supply power to the multiple electron guns in the order within a time less than or equal to 1 second; and / or, after supplying power to any one of the multiple electron guns is completed, the power supply is controlled to switch to supply power to another electron gun in the order within a time less than or equal to 1 second.

[0020] Another aspect of an embodiment of the present disclosure provides a pulse power supply device, including: a power supply; and a control unit, for controlling the power supply to execute the method as described in any one of the above items to provide pulse power supply to one or more electron guns.

[0021] In some embodiments, the power supply includes: a first voltage module, including at least one first submodule, the first submodule is configured to output a DC voltage with a fixed volt value; a second voltage module, including at least one second submodule, the second submodule is configured to output a DC voltage with a variable volt value.

[0022] Another aspect of an embodiment of the present disclosure provides a radiation device, comprising: a plurality of ray sources, including a plurality of electron guns corresponding to each other; and a power supply device as described in any one of the above items, wherein the power supply device is configured to provide pulse power supply to the plurality of electron guns.

[0023] One or more of the above embodiments have the following beneficial effects:

[0024] 1) By collecting at least one working parameter of the target electron gun in real time, it is possible to modulate part or all of the N pulse signals with the pulse signal as the control granularity, thereby achieving precise pulse level control of the electron beam output by the electron gun through pulse level control of the electron gun input.

[0025] 2) Provide a "one-to-many" power supply solution for multiple electron guns to share a common power supply. By using one power supply to alternately power multiple electron guns, it can save overall costs and achieve pulse-level control of the output of each electron gun, thereby achieving pulse-level precise beam control. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] The above contents and other purposes, features and advantages of the present disclosure will become more apparent through the following description of the embodiments of the present disclosure with reference to the accompanying drawings, in which:

[0027] Figure 1 A partial structural diagram of an ultra-high dose rate radiation device according to an embodiment of the present disclosure is schematically shown;

[0028] Figure 2 A flow chart of a pulse power supply method for an electron gun according to an embodiment of the present disclosure is schematically shown;

[0029] Figure 3 The schematic diagram shows a pulse power supply control architecture for an electron gun according to an embodiment of the present disclosure;

[0030] Figure 4 Schematically shows a flow chart of obtaining the target pulse signal by modulation according to an embodiment of the present disclosure;

[0031] Figure 5 A flowchart of dynamically adjusting power supply according to an embodiment of the present disclosure is schematically shown;

[0032] Figure 6 A flow chart schematically shows a pulse power supply method for multiple electron guns according to an embodiment of the present disclosure;

[0033] Figure 7 Schematically shows an architecture diagram for pulse power supply control of multiple electron guns according to an embodiment of the present disclosure;

[0034] Figure 8 The structure block diagram of the pulse power supply device for the electron gun according to the embodiment of the present disclosure is schematically shown;

[0035] Fig. 9 The structure block diagram of a pulse power supply device for multiple electron guns according to an embodiment of the present disclosure is schematically shown;

[0036] Fig.10 The structure block diagram of the power supply according to the embodiment of the present disclosure is schematically shown.

[0037] The reference numerals used in the above drawings include:

[0038] 100. Ultra-high dose rate radiation device; 110. Beam assembly; 111. First beam module; 112. Second beam module; 113. Third beam module; 114. Fourth beam module; 115. Fifth beam module; 140. Mounting support; 141. First support; 142. Second support; 120. Rotation assembly; 130. Target.

[0039] It should be noted that, for the sake of clarity, in the drawings used to describe the embodiments of the present disclosure, the sizes of the overall / local structures or the overall / local areas may be enlarged or reduced, that is, these drawings are not drawn according to the actual scale. DETAILED DESCRIPTION

[0040] Hereinafter, embodiments of the present disclosure will be described with reference to the accompanying drawings. However, it should be understood that these descriptions are exemplary only and are not intended to limit the scope of the present disclosure. In the following detailed description, for ease of explanation, many specific details are set forth to provide a comprehensive understanding of the embodiments of the present disclosure. However, it is apparent that one or more embodiments may also be implemented without these specific details. In addition, in the following description, descriptions of known structures and technologies are omitted to avoid unnecessary confusion of the concepts of the present disclosure.

[0041] Figure 1 The partial structure diagram of the ultra-high dose rate radiation device 100 according to the embodiment of the present disclosure is schematically shown.

[0042] like Figure 1 As shown, the ultra-high dose rate radiation device 100 includes a beam assembly 110, a rotation assembly 120 and a mounting support 140. The beam assembly 110 may include a plurality of beam modules for emitting multiple radiation beams, for example, a first beam module 111, a second beam module 112, a third beam module 113, a fourth beam module 114 and a fifth beam module 115. The mounting support 140 may include a first support 141 and a second support 142. The first beam module 111, the second beam module 112 and the third beam module 113 may be mounted on the first support 141, and the fourth beam module 114 and the fifth beam module 115 may be mounted on the second support 142.

[0043] For example, the radiation device 100 involved in the present disclosure may include an ultra-high dose rate radiation device, which generates a radiation beam that can be suitable for fields such as flash radiotherapy, container security inspection and industrial imaging, and can achieve ultra-high dose (for example, above 40Gy / s) radiation transfer, thereby completing the desired radiation in a very short time.

[0044] FLASH-RT uses ultrafast irradiation with dose rates that are orders of magnitude higher than those used in conventional radiation therapy (e.g., 20-100 Gy / s compared to 1-4 Gy / min). The high dose rate can reduce direct radiation-induced toxicity to normal tissues while maintaining the same effective response to diseased tissues. This is known as the "flash effect."

[0045] In some embodiments, the distances between the beam emission positions of the plurality of beam modules and the target portion 130 are substantially equal, which is beneficial for making the radiation effects of the beam modules on the radiotherapy area substantially consistent and also beneficial for the accuracy of calibration.

[0046] Exemplarily, the rotating assembly 120 may include a roller, a circular ring (or a fixed ring of other shapes, such as a hexagonal, triangular, or irregularly shaped fixed ring, etc.). The rotating assembly 120 may rotate around its rotation axis, thereby driving the first beam module 111, the second beam module 112, the third beam module 113, the fourth beam module 114, and the fifth beam module 115 to rotate. For example, during the calibration process, the center of the target portion 130 is located at the rotation axis of the rotating assembly 120. Thus, during the rotation process, the rotating assembly 120 may rotate around the target portion 130. During the rotation process, by switching different beam modules to emit beams, the same target portion 130 (for example, a lesion) may be irradiated at different angles, wherein the radiation beam emitted by each beam module may achieve the effect of ultra-high dose radiation. Multiple beam modules may emit beams in a sequential order and in a relative position to a predetermined radiation area, or may emit beams in a disrupted order. Even when necessary, beams may be emitted for treatment at the same time.

[0047] By setting a plurality of beam modules of different angles on a rotatable rotary assembly 120, the beam modules generating radiation are switched to achieve the purpose of rapidly performing irradiation treatment at multiple angles in a very short time required in flash radiotherapy. That is, after calibration is completed, ultra-high dose irradiation can be achieved at multiple angles for a predetermined radiation area through the cooperation of the rotary assembly 120 and the plurality of beam modules.

[0048] For example, the beam module may include an electron linear accelerator. The radiation beam may include an X-ray beam. For example, the rotary assembly 120 has a receiving space therein, which may receive a target object to be radiotherapy. Figure 1 The target portion 130 is shown as a schematic location, which may be located within the rotating assembly 120. For example, a lesion of a target object (eg, a person) may be adjusted to the target portion 130 and then irradiated by one or more radiation beams.

[0049] Understandably, Figure 1 The number, position and installation relationship of the middle beam modules are only examples and can be flexibly determined according to needs.

[0050] The following will be based on Figure 1 The described structure describes in detail the pulse power supply method for an electron gun according to an embodiment of the present disclosure.

[0051] Figure 2 The flowchart of the pulse power supply method for an electron gun according to an embodiment of the present disclosure is schematically shown. Figure 3 The schematic diagram shows an architecture diagram of pulse power supply control for an electron gun according to an embodiment of the present disclosure.

[0052] like Figure 2 As shown, this embodiment includes:

[0053] In operation S210, at least one operating parameter of the target electron gun is collected in real time;

[0054] like Figure 1 The first beam module 111, the second beam module 112, the third beam module 113, the fourth beam module 114 and the fifth beam module 115 are modularly designed and are independent of each other. Each beam module includes an electron gun device. The target electron gun can be an electron gun in any beam module.

[0055] For example, one or more sensors may be used to collect operating parameters of the electron gun in the startup state when preparing to emit an electron beam or in the process of emitting an electron beam, which may include temperature, cathode emission current density, potential distribution, space charge distribution, vacuum degree, gun voltage, gun current, etc. It can be understood that at least one operating parameter collected in real time in operation S210 is related to the parameters of the emitted electron beam.

[0056] In operation S220, N pulse signals are transmitted to the target electron gun at intervals for power supply, wherein any two adjacent pulse signals are transmitted at intervals, and N is an integer greater than or equal to 2. Modulation includes adjusting the characteristics of the pulse signal, such as amplitude, frequency, etc., according to certain operating parameters to adapt to different operating conditions.

[0057] In some embodiments, at least one of the N pulse signals is modulated according to at least one operating parameter. For example, for any two adjacent pulse signals, the latter pulse signal is modulated according to the at least one operating parameter collected after the previous pulse signal is transmitted to the target electron gun.

[0058] Exemplarily, the interval transmission in operation S220 refers to transmitting two adjacent pulse signals in the N pulse signals at a certain interval, for example, a time interval between 0.1 microseconds and 1 millisecond, or 1 millisecond and hundreds of milliseconds. That is, the N pulse signals include a series of voltage peaks transmitted at a certain interval, which are used to control the emission of the electron beam.

[0059] It can be understood that under different pulse signals, the electron gun has different electron emission capabilities. Two different pulse signals make the electron gun emit different electron beams. Because of many factors such as the service life of the electron gun, the single continuous beam emission time, the temperature change during the beam emission period, the manufacturing process, the material difference, and the different production batches after the replacement of spare parts, the performance of the electron emission of different electron guns is different, which is particularly obvious in the multi-electron gun system.

[0060] Therefore, the working state of the target electron gun can be monitored in real time, and the pulse parameters can be adjusted in time according to the dynamic changes of the gun state, so as to maintain the overall working state stability. For example, if the working parameters collected in real time before transmission of the first pulse signal and the second pulse signal of the N pulse signals are different, then under the premise of outputting the same electron beam, the first pulse signal and the second pulse signal have different amplitudes and widths.

[0061] According to an embodiment of the present disclosure, by collecting at least one working parameter of the target electron gun in real time, it is possible to modulate part or all of N pulse signals with the pulse signal as the control granularity, thereby achieving precise control of the pulse level of the electron beam output by the electron gun through pulse level control of the electron gun input.

[0062] In some embodiments, the at least one operating parameter includes a gun voltage and a gun current of the target electron gun, and at least one of the N pulse signals is modulated according to the gun voltage and the gun current.

[0063] For example, the at least one operating parameter includes Figure 3The key parameters 1, 2, ..., Y are shown. The measured values ​​are the actual collected working parameter values. The gun voltage of the electron gun includes the voltage obtained by collecting the circuit voltage in the electron gun, which is used to establish a high voltage electric field between the cathode and anode of the electron gun to accelerate the electrons. The gun current can be obtained based on one or more of the cathode current, the grid current, the current of the previous electron beam, or the current of other regions. For example, it can be obtained by measuring a certain current value or by adding multiple current values.

[0064] For example, the pulse voltage amplitude, pulse width, and interval time between the adjacent previous pulse signal of the pulse signal to be transmitted are modulated. Figure 1 The equipment is used to determine the mapping relationship between different electron beams and different doses through experiments in advance, and to determine the different working parameters and different pulse signal combinations in advance. The obtained electron beam parameters are stored as a data table, or a mathematical model (expressed as a mathematical equation) is obtained by fitting. Figure 3 The basic algorithm values ​​shown are shown in Figure 2. Modulation is achieved by looking up a table or inputting it into a mathematical model.

[0065] According to the embodiments of the present disclosure, the gun voltage and gun current collected in real time can be reflected to the input side, and the pulse signal to be transmitted can be precisely modulated to facilitate accurate control of the output electron beam.

[0066] In some embodiments, at least one of the N pulse signals is modulated according to the gun voltage and the gun current, which includes: based on the gun voltage and the gun current, determining the pulse voltage and the pulse width of the pulse signal to be transmitted according to a preset first mapping relationship.

[0067] The first mapping relationship may refer to the correspondence between the gun voltage, gun current and the pulse voltage and pulse width. For example, it may be pre-stored in the form of a data table or a mathematical model. For example, the relationship between the gun voltage, gun current and the pulse voltage and pulse width is determined using linear regression analysis. The first mapping relationship describes the process of calculating the pulse voltage and pulse width by taking the gun voltage and gun current as input under the determined electron beam parameters. Figure 3 The basic algorithm values ​​in the workflow. For example, if the gun voltage is 150kV and the gun current is 0.5mA, the system looks up the table or uses the mathematical model to calculate the corresponding pulse voltage to be 10kV and the pulse width to be 1 microsecond (just an example).

[0068] According to the embodiments of the present disclosure, the first mapping relationship can be used to implement an automated modulation process, thereby reducing the time for manual adjustment and reducing resource consumption and time required for automated adjustment.

[0069] In some embodiments, for a target pulse signal that is not transmitted for the first time among the N pulse signals, the method further includes: modulating the pulse voltage and pulse width of the target pulse signal according to the gun voltage and gun current, and the last actual dose. The last actual dose includes the actual dose output by the radiation source to which the target electron gun belongs after the last pulse signal of the target pulse signal is transmitted.

[0070] The first transmission refers to the first pulse signal transmitted to the target electron gun among N pulse signals. The radiation source includes Figure 1 For example, when the target pulse signal corresponds to the same dose as the previous pulse signal, Figure 3 In the negative feedback algorithm value, it is found that the previous actual dose is lower than expected. By increasing the pulse voltage and pulse width of the target pulse signal, the output of the radiation source can reach the expected dose. The expected dose can be the dose corresponding to itself, or the compensation value of the previous actual dose can be increased on this basis.

[0071] According to the embodiments of the present disclosure, it is possible to participate in the precise modulation of the target pulse signal according to the last actual output of the ray source and the working parameters of the electron gun itself, thereby realizing the pulse level control of the electron gun output.

[0072] Figure 4 The flowchart of modulating to obtain a target pulse signal according to an embodiment of the present disclosure is schematically shown.

[0073] like Figure 4 As shown, this embodiment includes:

[0074] In operation S410, the gun voltage and the gun current are corrected according to a second mapping relationship between the gun voltage and the gun current of the target electron gun when the last pulse signal is transmitted and the last actual dose;

[0075] In operation S420, a pulse voltage and a pulse width of a target pulse signal are determined according to the corrected gun voltage and gun current.

[0076] The second mapping relationship includes the correspondence between the gun voltage, gun current and actual dose when the last pulse signal was transmitted. According to the second mapping relationship and the deviation between the last actual dose and the target dose, the theoretical gun voltage and theoretical gun current required for the radiation source to reach the corresponding dose after the target pulse signal is transmitted can be converted. Then, according to the difference between the actual gun voltage and actual gun current collected and their respective theoretical values, correction is performed when the difference is greater than a certain range (such as the deviation exceeds 10%). Then, the corrected gun voltage and gun current can be the aforementioned theoretical values, and the pulse voltage and pulse width of the target pulse signal can be inferred on this basis, and then modulated and transmitted.

[0077] According to the embodiments of the present disclosure, adaptive correction can be performed according to the actual electron gun performance and the actual output of the ray source, and precise control of the electron beam can be achieved under different operating conditions, thereby improving the stability and reliability of the ray source output.

[0078] Figure 5 The flowchart of dynamically adjusting power supply according to an embodiment of the present disclosure is schematically shown.

[0079] like Figure 5 As shown, this embodiment is one of the embodiments of operation S220, including:

[0080] In operation S510, after transmitting M pulse signals, a first superimposed dose of a radiation source to which a target electron gun belongs is obtained, wherein the first superimposed dose includes a sum of actual doses output by the radiation source measured in response to transmitting the M pulse signals, and M is less than or equal to N;

[0081] For example, if each pulse signal generates a dose of 1 unit and 5 pulse signals are delivered, the first superimposed dose is 5 units.

[0082] In operation S520, in response to each of the N pulse signals being delivered, the number of pulse signals to be delivered is determined according to the difference between the first superimposed dose and the target dose, that is, the number of pulse signals to be subsequently delivered to the target electron gun. In some embodiments, the pulse width and pulse voltage of each subsequent pulse signal to be delivered may also be re-determined.

[0083] According to the embodiments of the present disclosure, the subsequent pulse signals can be dynamically adjusted according to the actual output dose, thereby achieving precise control of the output dose of the radiation source to which the target electron gun belongs.

[0084] In some embodiments, determining the number of pulse signals to be delivered according to the difference between the first superimposed dose and the target dose includes:

[0085] When M is less than N and the first superimposed dose is less than the target dose, continue to deliver the pulse signal to be delivered among the N pulse signals. The number of pulse signals to be delivered in this step is the difference between N and M. For example, the modulated pulse signal to be delivered can be continued to be executed, and the pulse width and pulse voltage of each subsequent modulated pulse signal to be delivered can be re-determined according to the difference between the first superimposed dose and the target dose to achieve the task of outputting the target dose.

[0086] When M is less than N and the first superimposed dose is greater than or equal to the target dose, stop delivering the pulse signal to be delivered among the N pulse signals, and this step determines that the number of the pulse signals to be delivered is 0;

[0087] When M is equal to N and the first superimposed dose is less than the target dose, a predetermined number of pulse signals to be delivered is added and delivered. The predetermined number may include: delivering one according to the original pulse signal parameters, and detecting in real time whether the first superimposed dose reaches the target dose, and if not, continuing to deliver one until the target dose is achieved.

[0088] In some embodiments, the predetermined number may also include: according to the maximum dose corresponding to each pulse signal, the differential dose is split, allocated to one or more pulse signals and transmitted, wherein operations S510 to S520 can be repeatedly performed, for example, after transmitting S pulse signals, a second superimposed dose of the radiation source to which the target electron gun belongs is obtained, wherein the second superimposed dose includes the sum of the actual doses output by the radiation source measured in response to the transmission of S pulse signals, and S is an integer greater than or equal to 1; in response to any one of the predetermined number of pulse signals to be transmitted being transmitted, the number of subsequent pulse signals to be transmitted is determined according to the difference between the sum of the first superimposed dose and the second superimposed dose and the target dose.

[0089] In some embodiments, intermittently transmitting N matching pulse signals to the target electron gun includes: the interval between any two adjacent pulse signals transmitted is less than or equal to 1 millisecond.

[0090] For example, in the flash radiotherapy scenario, the width of the electron gun pulse high voltage, that is, the effective working time of the electron gun, can be 10 microseconds, and the longest is no more than tens of microseconds (only for example), the duty cycle of the effective time is not high, the rest of the time is idle, and at any time, there is only one electron gun working. Preferably, a pulse signal is transmitted within 1 millisecond, and its pulse width is 10 microseconds, then the interval time for transmitting the next pulse signal is 990 microseconds.

[0091] The following will be based on Figure 1~Figure 5 The above description describes in detail the pulse power supply method for multiple electron guns according to an embodiment of the present disclosure.

[0092] Figure 6 The flowchart of the pulse power supply method for multiple electron guns according to the embodiment of the present disclosure is schematically shown. Figure 7 The diagram schematically shows an architecture diagram for pulse power supply control of multiple electron guns according to an embodiment of the present disclosure.

[0093] like Figure 6 As shown, this embodiment includes:

[0094] In operation S610, an order (eg, Figure 7a trigger sequence for each gun in the electron guns), and a pulse sequence matching the electron guns in each ray source, the pulse sequence comprising N pulse signals, where N is an integer greater than or equal to 2;

[0095] In operation S620, the power supply is controlled to alternately deliver matching pulse sequences to the multiple electron guns in the multiple ray sources in order to supply power. Figure 1~Figure 5 And the pulse power supply method for the electron gun shown in each embodiment.

[0096] For example, the working state of the electron gun can be monitored in real time, and the pulse parameters can be adjusted in time according to different gun states. A closed-loop control algorithm can be used to achieve a normalized working effect for each gun, thereby maintaining the overall working state of the device stable. The time between two electron gun pulses can be used to realize each submodule (as shown below): Fig.10 ) and the gating of different electron gun ports, so as to realize the delivery of different high-precision DC pulse high voltage to different electron guns.

[0097] Reference Figure 7 , the host system can be a control unit, such as a computer, PLC controller, etc. The user can interact with the host system to issue radiation task requirements. Relationship parameter 1, concern parameter 2... concern parameter U (such as environmental factors such as air humidity, altitude, temperature, and the stability of the mains power supply, etc.) can be used as input to implement parameter analysis, dose analysis, and sequence decomposition, and obtain the pulse number and pulse dose of electron gun 1, electron gun 2... electron gun M.

[0098] like Figure 1 For a multi-electron gun system, the delivery order of each electron gun can be different under different radiation task requirements. Figure 7 As shown, pulse control is achieved through a modular power supply and a high-speed processor, that is, the parameters of the previous pulse signal and the electron gun port can be different from the parameters of the next pulse signal and the electron gun parameters, or the parameters of the previous pulse sequence and the electron gun port can be different from the parameters of the next pulse sequence and the electron gun parameters.

[0099] In some embodiments, obtaining the order in which multiple ray sources send multiple ray beams to the same target portion 130 includes: configuring each ray source to send a radiation beam once or multiple times, wherein at least one remaining ray source is configured to send a radiation beam between two adjacent times.

[0100] The triggering sequence and working parameters of each electron gun are not restricted. Assuming there are 5 electron guns, they can be triggered in the order of 1-2-3-4-5, or in the order of 2-4-5, or in the order of 1-2-3-2, that is, they can be triggered in any combination, so as to maximize the overall performance of the multi-electron gun system. High-speed data processing algorithms can be used to quickly decompose radiation task information, such as specific dose requirements under ultra-high dose radiation, into the dose (pulse dose) achieved by the single pulse signal of each electron gun, the number of pulses delivered (i.e., the value of N), and the trigger timing.

[0101] Figure 7 The figure shows the final dose supplement (final dose supplement sequence). For example, for each electron gun, the number of pulse signals to be delivered can be determined and modulated according to the difference between the first superimposed dose and the target dose. For example, the radiation source to which electron gun 1 belongs needs to complete a dose of 20 cGy. After completing a certain number of pulses as planned, the actual measured dose is less than 20 cGy, and 1-2 pulses are added to make up to the target 20 cGy. If the measured dose is sufficient, no more supplementation is required. For another example, one or more electron guns can be designated to be triggered again one or more times for dose supplementation according to the difference between the total superimposed dose and the total target dose after the multi-electron gun is triggered as a whole.

[0102] According to the embodiments of the present disclosure, a "one-to-many" power supply scheme is provided, and multiple electron guns share a power supply. By alternately supplying power to multiple electron guns with one power supply, the overall cost can be saved, and pulse-level control of the output of each electron gun can be achieved, thereby achieving pulse-level precise beam control.

[0103] In some embodiments, the power supply is controlled to complete powering the multiple electron guns alternately in sequence within a time less than or equal to 1 second; and / or, after powering any one of the multiple electron guns is completed, the power supply is controlled to switch to powering another electron gun in sequence within a time less than or equal to 1 second (such as switching within a time interval of 1 millisecond).

[0104] In some embodiments, multiple electron guns correspond to multiple power supply ports one by one, and controlling the power supply to alternately transmit matching pulse sequences to the multiple electron guns in the multiple radiation sources in sequence for power supply includes: controlling the power supply to alternately select the power supply ports of the corresponding electron guns (i.e., the above-mentioned electron gun ports) in sequence, for example, switching the selected power supply ports within a time less than or equal to 1 second (such as switching within a time interval of 1 millisecond).

[0105] According to the embodiments of the present disclosure, one power supply can power different electron guns, and the parameters of a single pulse signal are adjustable, that is, the pulse high voltage amplitude and pulse width are adjustable, and the power supply port output can also be specified to achieve fast and reliable switching in a complex electromagnetic environment.

[0106] In some embodiments, obtaining a pulse sequence that matches the electron gun in each radiation source includes: allocating multiple target doses to multiple radiation sources one by one according to radiation task information, wherein any two target doses are the same or different; and determining a pulse sequence that matches the electron gun therein according to the target dose of each radiation source.

[0107] Exemplarily, multiple radiation sources correspond to multiple beam modules that are modularly designed and independent of each other. Radiation task information may include the dose information required for a flash radiotherapy, such as 100 cGy. The five target doses assigned to the five radiation sources may all be 20 cGy, or may be 30 cGy, 20 cGy, 10 cGy, 15 cGy, and 25 cGy. The target doses of different radiation sources can be determined based on the relative position between the position where the radiation beam is emitted and the target. For example, a radiation source emits a radiation beam that passes through important organs of the human body, which can give them a lower target dose.

[0108] According to the embodiments of the present disclosure, multiple electron guns are taken as a whole, and the target dose is allocated in a coordinated manner in combination with the radiation task information, and then a pulse sequence that can achieve the target dose is obtained, thereby achieving the effect of adjustable parameters of a single pulse signal of a single electron gun and coordinated control of multiple electron guns.

[0109] In some embodiments, determining a pulse sequence matching an electron gun therein according to a target dose of each ray source includes: determining a sub-dose corresponding to each pulse signal in N pulse signals according to the target dose of each ray source; wherein the target dose is obtained by superposition of the N sub-doses.

[0110] For example, the target dose of electron gun 1 is 30 cGy. The maximum dose corresponding to a single pulse signal, such as 3 cGy, can be obtained based on the factory parameters, service life, temperature, and historical beam data of electron gun 1, and then 10 pulse signals can be obtained to form a pulse sequence.

[0111] According to the embodiments of the present disclosure, high-precision pulse high voltages of different pulse signals are transmitted to different electron guns, thereby achieving pulse level control of the electron guns and finely and accurately controlling the output dose of the radiation source.

[0112] In some embodiments, obtaining the order in which multiple radiation sources send multiple radiation beams to the same target portion 130 includes: obtaining the time when each radiation source sends the radiation beam, and the position at the corresponding time; wherein different radiation sources send radiation beams at different times, and the position of each radiation source is dynamically adjustable. Figure 1 , for example, by rotating the rotating assembly 120 to adjust the position of each ray source.

[0113] Figure 8The structure block diagram of a pulse power supply device 800 for an electron gun according to an embodiment of the present disclosure is schematically shown.

[0114] In some embodiments, a pulse power supply device 800 for an electron gun includes:

[0115] A collection module 810, which can perform operation S210, for collecting at least one working parameter of a target electron gun in real time;

[0116] The power supply module 820 can perform operation S220 to transmit N pulse signals to the target electron gun at intervals for power supply, where N is an integer greater than or equal to 2; wherein at least one of the N pulse signals is modulated according to at least one working parameter.

[0117] In some embodiments, the pulse power supply device 800 for an electron gun also includes a control unit 830, which is used to obtain a first superimposed dose of the radiation source to which the target electron gun belongs after transmitting M pulse signals, wherein the first superimposed dose includes the sum of actual doses output by the radiation source measured in response to the transmission of M pulse signals, and M is less than or equal to N; in response to each of the N pulse signals being transmitted, the number of pulse signals to be transmitted is determined according to the difference between the first superimposed dose and the target dose.

[0118] In some embodiments, the control unit is also used to continue executing the pulse signal to be delivered among the N pulse signals when M is less than N and the first superimposed dose is less than the target dose; to stop executing the pulse signal to be delivered among the N pulse signals when M is less than N and the first superimposed dose is greater than or equal to the target dose; and to increase and execute a predetermined number of pulse signals to be delivered when M is equal to and the first superimposed dose is less than the target dose.

[0119] It can be understood that the pulse power supply device 800 for an electron gun includes a module for implementing the steps of any embodiment of the pulse power supply method for an electron gun as described above, and can solve the same technical problem and achieve the same technical effect.

[0120] Fig. 9 The structure block diagram of a pulse power supply device 900 for multiple electron guns according to an embodiment of the present disclosure is schematically shown.

[0121] In some embodiments, the pulse power supply device 900 for multiple electron guns includes: a power supply 910; and a control unit 920, which is used to execute one or more steps of the pulse power supply method for multiple electron guns as described above to provide pulse power supply to the multiple electron guns.

[0122] In some embodiments, the power supply may include a power supply module 920 as described above for the pulse power supply device of the electron gun. The control unit 920 may be the same as the control unit 830 .

[0123] It can be understood that the pulse power supply device 900 for an electron gun includes a module for implementing the steps of any embodiment of the pulse power supply method for multiple electron guns as described above, and can solve the same technical problem and achieve the same technical effect.

[0124] In some embodiments, the pulse power supply device 900 for multiple electron guns may include the pulse power supply device 800 for multiple electron guns as described above.

[0125] Fig.10 The structural block diagram that can implement pulse power supply according to an embodiment of the present disclosure is schematically shown.

[0126] In some embodiments, the power supply may include a first voltage module and a second voltage module. The first voltage module includes at least one first submodule configured to output a DC voltage with a fixed volt value; the second voltage module includes at least one second submodule configured to output a DC voltage with a variable volt value.

[0127] like Fig.10 As shown, firstly, the AC mains is modulated into a lower voltage DC as a submodule of the power supply. According to the principle of "series voltage addition", multiple submodules are connected in series to realize the main circuit from AC 380V mains to DC pulse high voltage. By selecting different numbers of submodules, different DC pulse high voltage volt values ​​can be obtained. In order to improve the adjustment accuracy of DC pulse high voltage, some modules with adjustable DC voltage are set up for ready call according to the pulse voltage accuracy requirements.

[0128] Combination Fig.10 In general, at least one first submodule includes submodule 1, submodule 2, ..., submodule N, and at least one second submodule includes submodule a1, submodule a2, ..., submodule aK. Fig.10 The voltage fixed module can be used to receive instructions from the control unit, select one or more of submodule 1, submodule 2...submodule N to start, wherein each submodule can convert 380V AC power into a DC pulse voltage with a fixed amplitude. The voltage adjustable module can be used to receive instructions from the control unit, select one or more of submodule a1, submodule a2...submodule aK to start, wherein each submodule can convert 380V AC power into a DC pulse voltage with adjustable amplitude. Then, a pulse high voltage can be obtained, and through the output port selection step, in response to delivering a specific pulse high voltage and pulse width to the target electron gun, the delivery of the pulse signal is realized.

[0129] For example, submodule 1, submodule 2, ..., submodule N can each output a fixed DC pulse of 1000V. If the voltage needs to be boosted to 7500V, submodule 1 to submodule 7 are selected, and then a submodule a1 is coordinated to adjust it to 500V, so as to achieve the voltage boost result of 7500V by selecting 8 submodules. By utilizing the interval between two pulse signals of the same electron gun, or the interval between switching of two electron guns, the combination of each submodule and the selection of different output ports are realized, so as to realize the transmission of different high-precision DC pulse high voltages to different electron guns.

[0130] In some embodiments, the present disclosure also provides a radiation device, which includes: Figure 1 The ultra-high dose rate radiation device 100 shown. The radiation device can be configured with multiple radiation sources, and the multiple radiation sources include multiple electron guns corresponding to each other. The radiation device can also include any power supply device as described above.

[0131] It will be appreciated by those skilled in the art that the features described in the various embodiments of the present disclosure may be combined and / or combined in a variety of ways, even if such combinations or combinations are not explicitly described in the present disclosure. In particular, without departing from the spirit and teachings of the present disclosure, the features described in the various embodiments of the present disclosure may be combined and / or combined in a variety of ways. All of these combinations and / or combinations fall within the scope of the present disclosure.

[0132] The embodiments of the present disclosure are described above. However, these embodiments are only for illustrative purposes and are not intended to limit the scope of the present disclosure. Although the embodiments are described above separately, this does not mean that the measures in the various embodiments cannot be used in combination to advantage. The scope of the present disclosure is defined by the attached claims and their equivalents. Without departing from the scope of the present disclosure, those skilled in the art may make a variety of substitutions and modifications, which should all fall within the scope of the present disclosure.

Claims

1. A pulse power supply method for an electron gun, comprising: collecting at least one operating parameter of a target electron gun in real time, wherein the at least one operating parameter includes a gun voltage and a gun current of the target electron gun; Transmitting N pulse signals to the target electron gun at intervals for power supply, wherein any two adjacent pulse signals are transmitted at intervals, and N is an integer greater than or equal to 2; Wherein, at least one of the N pulse signals is modulated according to the at least one working parameter.

2. The method according to claim 1, characterized in that: At least one of the N pulse signals is modulated according to the gun voltage and the gun current and includes: Based on the gun voltage and the gun current, the pulse voltage and the pulse width of the pulse signal to be transmitted are determined according to a preset first mapping relationship.

3. The method according to claim 1 or 2, characterized in that: At least one of the N pulse signals is modulated according to the at least one working parameter and further comprises: For any two adjacent pulse signals, the latter pulse signal is modulated according to the at least one working parameter collected after the previous pulse signal is transmitted to the target electron gun.

4. The method according to claim 3, characterized in that For the target pulse signal that is not transmitted for the first time among the N pulse signals, the method further includes: According to the gun voltage and gun current, and the last actual dose, modulate the pulse voltage and pulse width of the target pulse signal; The last actual dose includes the actual dose output by the ray source to which the target electron gun belongs after the last pulse signal of the target pulse signal is transmitted.

5. The method according to claim 4, characterized in that Modulating the pulse voltage and pulse width of the target pulse signal includes: According to a second mapping relationship between a gun voltage and a gun current of the target electron gun when the previous pulse signal is transmitted and the previous actual dose, the gun voltage and the gun current are corrected; The pulse voltage and pulse width of the target pulse signal are determined according to the corrected gun voltage and gun current.

6. The method according to claim 1, characterized in that The step of transmitting N matching pulse signals to the target electron gun at intervals comprises: After transmitting M pulse signals, obtaining a first superimposed dose of the radiation source to which the target electron gun belongs, wherein the first superimposed dose includes the sum of actual doses output by the radiation source measured in response to transmitting the M pulse signals, and M is less than or equal to N; In response to any one of the N pulse signals being delivered, the number of subsequent pulse signals to be delivered is determined according to a difference between the first superimposed dose and the target dose.

7. The method according to claim 6, characterized in that Determining the number of subsequent pulse signals to be delivered according to the difference between the first superimposed dose and the target dose includes: When M is less than N and the first superimposed dose is less than the target dose, continue to deliver the pulse signal to be delivered among the N pulse signals; When M is less than N and the first superimposed dose is greater than or equal to the target dose, stopping the execution of the pulse signal to be delivered among the N pulse signals; When M is equal to N and the first superimposed dose is less than the target dose, a predetermined number of pulse signals to be delivered are added and delivered.

8. The method according to claim 7, characterized in that The step of increasing and transmitting a predetermined number of pulse signals to be transmitted comprises: After delivering S pulse signals, obtaining a second superimposed dose of the radiation source to which the target electron gun belongs, wherein the second superimposed dose includes the sum of actual doses output by the radiation source measured in response to delivering the S pulse signals, and S is an integer greater than or equal to 1; In response to any one of the predetermined number of pulse signals to be delivered being delivered, the number of subsequent pulse signals to be delivered is determined according to a difference between a sum of the first superimposed dose and the second superimposed dose and the target dose.

9. The method according to any one of claims 1 to 2, 4 to 8, wherein The step of transmitting N matching pulse signals to the target electron gun at intervals comprises: The interval between any two adjacent pulse signals is less than or equal to 1 millisecond.

10. A pulse power supply method for multiple electron guns, comprising: Acquire the order in which multiple ray sources send multiple ray beams to the same target portion, and a pulse sequence matched with an electron gun in each ray source, wherein the pulse sequence includes N pulse signals, where N is an integer greater than or equal to 2; Based on the method described in any one of claims 1 to 9, the power supply is controlled to alternately transmit matching pulse sequences to the multiple electron guns in the multiple ray sources in the sequence to provide power.

11. The method according to claim 10, characterized in that The multiple electron guns correspond one by one to the multiple power supply ports, The controlling the power supply to alternately deliver matching pulse sequences to the multiple electron guns in the multiple ray sources in the order to supply power comprises: The power supply is controlled to alternately enable the power supply ports corresponding to the electron guns in the order.

12. The method according to claim 10, characterized in that Acquiring a pulse sequence that matches the electron gun in each source involves: Allocating a plurality of target doses to the plurality of radiation sources one by one according to the radiation task information, wherein any two target doses are the same or different; A pulse sequence matching the electron gun therein is determined according to the target dose of each ray source.

13. The method according to claim 12, characterized in that Determining a pulse sequence matching the electron gun therein according to the target dose of each ray source includes: Determining a sub-dose corresponding to each pulse signal in the N pulse signals according to a target dose of each radiation source; The target dose is obtained by superimposing N sub-doses.

14. The method according to any one of claims 10 to 13, characterized in that: The order of obtaining the multiple ray sources to send multiple ray beams to the same target portion comprises: Obtaining the time when each ray source sends a ray beam, and the position at the corresponding time; Different ray sources send ray beams at different times, and the position of each ray source is dynamically adjustable.

15. The method according to any one of claims 10 to 13, characterized in that: Controlling the power supply to supply power to the plurality of electron guns alternately in the order within a time less than or equal to 1 second; and / or, After the power supply to any one of the plurality of electron guns is finished, the power supply is controlled to switch to supply power to another electron gun in the order within a time less than or equal to 1 second.

16. A pulse power supply device, comprising: Power supply; A control unit is used to control the power supply to execute the method of any one of claims 1 to 14 or any one of claims 10 to 15 to provide pulse power supply to one or more electron guns.

17. The device according to claim 16, characterized in that The power supply comprises: A first voltage module, comprising at least one first submodule, wherein the first submodule is configured to output a DC voltage of a fixed volt value; The second voltage module includes at least one second submodule, and the second submodule is configured to output a variable DC voltage.

18. A radiation device, comprising: A plurality of ray sources, including a plurality of electron guns corresponding to each other; as well as The power supply device according to any one of claims 16 or 17, wherein the power supply device is configured to provide pulse power to the plurality of electron guns.

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