Sampling device for tumor tissue

Abstract

The invention discloses a sampling device for tumor tissues, and relates to the technical field of tumor detection. The device comprises a needle tube, the top of the needle tube is provided with a wire groove, the periphery of the bottom of the needle tube is fixedly provided with a connector, the bottom of the needle tube is fixedly connected with an operation cylinder in a threaded mode, the operation cylinder is internally provided with a sampling assembly, and the operation cylinder is internally provided with a suction assembly. The suction assembly is used for driving the sampling assembly to sample tumor tissues, the top end of the needle tube adopts a closed design, and the wire slot penetrates through the outer wall of the needle tube. In the process of puncturing the tumor tissue at one time, the tumor tissue can be sampled in different positions and different directions, the sampling difficulty is reduced, meanwhile, repeated puncturing is not needed, the sampling efficiency is improved, damage to a patient is reduced, after sampling is completed, the sampling barrel can be sealed, and the sampling efficiency is improved. The pollution of the external environment to the sample is avoided, and the accuracy of the detection result is ensured.

Description

Technical Field

[0001] The present invention relates to the technical field of tumor detection, and in particular to a sampling device for tumor tissue. Background Art

[0002] Tumor detection is an important part of tumor pathology diagnosis. During the tumor detection process, tumor tissue needs to be sampled and tested. In order to improve convenience and reduce damage to patients, some subcutaneous tumor tissues are often sampled by extracting a combination of materials and blood using a syringe.

[0003] However, the existing tumor tissue sampling device still has the following defects during use:

[0004] 1. When sampling, the existing needle-tube extraction type tumor tissue sampling device directly inserts the needle into the tumor tissue for extraction. Only a single sampling can be completed at a time, and the accuracy of the needle insertion is high, which increases the difficulty of operation. In order to be able to sample at different locations of the tumor tissue, the needle needs to be inserted into different locations of the tumor tissue for multiple times for sampling. Not only is the operation cumbersome, it reduces the sampling efficiency and also increases the damage to the patient.

[0005] 2. After the existing needle-tube extraction type tumor tissue sampling device is completed and the needle is extracted from the patient's skin, the needle of the needle tube can be sealed, which can easily cause contamination to the extracted sample and affect the test results. Summary of the invention

[0006] The purpose of the present invention is to solve the problem that the above-mentioned needle insertion can only complete a single sampling, and the accuracy of the needle insertion is required to be high. When performing multiple sampling at different positions, repeated insertion is required, which not only makes the operation cumbersome and reduces the efficiency of sampling, but also increases the damage to the patient. In addition, the needle tube is not sealed, which easily causes contamination to the removed sample and affects the detection results. The present invention provides a sampling device for tumor tissue.

[0007] In order to achieve the above-mentioned purpose, the present invention specifically adopts the following technical solutions:

[0008] A tumor tissue sampling device comprises a needle tube, a wire groove is provided on the top of the needle tube, a connector is fixedly installed on the periphery of the bottom of the needle tube, an operating cylinder is threadedly fixedly connected to the bottom of the needle tube, a sampling component is arranged inside the operating cylinder, a suction component is arranged inside the operating cylinder, and the suction component is used to drive the sampling component to sample tumor tissue.

[0009] Furthermore, the top of the needle tube adopts a closed design, the wire groove runs through the outer wall of the needle tube, and the wire groove is divided into two groups. The two groups of wire grooves are arranged up and down on the top of the needle tube, and the two groups of wire grooves are staggered and vertically distributed. The wire groove is connected to the inside of the needle tube, so that different positions and different directions of the tumor tissue can be sampled through the wire groove.

[0010] Furthermore, an internal thread is provided inside the bottom of the connector, and an external thread is provided outside the top of the operating cylinder, and the threaded fixed connection between the needle tube and the operating cylinder is achieved through the cooperation of the internal thread and the external thread.

[0011] Furthermore, the sampling assembly includes a sampling cylinder, which is connected to the sampling cylinder in a limited sliding manner at the top of the needle tube, and two cylindrical grooves symmetrically arranged in the upper and lower parts are provided inside the sampling cylinder. Circular holes are provided at the tops of the two cylindrical grooves, and pistons are connected to the tops of the two cylindrical grooves in a limited sliding manner. A pull rod is fixedly installed at the center of the piston, and the pull rod extends downward to the bottom of the connecting head. The pistons in the two cylindrical grooves are pulled simultaneously by the pull rod to move, and a spiral pattern is provided on the periphery of the lower half of the pull rod.

[0012] Furthermore, the circular hole penetrates the outer wall of the sampling tube and is connected to the cylindrical groove, and the circular holes at the top of the two cylindrical grooves are respectively aligned with the two groups of linear grooves distributed above and below, so that the tumor tissue can enter the cylindrical groove of the sampling tube through the linear grooves and the circular hole.

[0013] Furthermore, when the piston is at the initial position at the top of the cylindrical groove, it can block the circular hole, so that the sampling tube is in a closed state in the initial state.

[0014] Furthermore, the suction assembly includes a turntable, the bottom of the operating cylinder is rotatably connected to the turntable, the center of the top of the turntable is rotatably connected to the turntable, the top of the turntable is fixedly connected to a spring so that the spring and the turntable can rotate on the top of the turntable, the bottom end of the operating cylinder is fixedly installed with a gear ring, the gear ring is concentric with the turntable, the upper part of the gear ring inside the operating cylinder is rotatably connected to a threaded rod, and the threaded rod and the gear ring are meshed with each other, so that during the rotation of the threaded rod, the gear ring and the turntable can be driven to rotate, the two ends of the threaded rod extend to the outside of the operating cylinder, and the two ends of the threaded rod are symmetrically fixed with wheels for driving the threaded rod to rotate.

[0015] Furthermore, when the needle tube is installed, the pull rod passes through the turntable downward at the center of the spring, and the spiral pattern of the pull rod is threadedly connected to the turntable, so when the turntable rotates, the pull rod can be driven to move.

[0016] Furthermore, after the needle tube and the operating cylinder are installed, the spring is in compression contact with the bottom end of the sampling cylinder, so that after the installation is completed, under the action of the spring, the sampling cylinder inside the needle tube is located at the top of the needle tube.

[0017] The beneficial effects of the present invention are as follows:

[0018] 1. The present invention, through the design of the sampling component and the suction component, cooperates with the distribution design of the wire groove on the needle tube, and utilizes the suction component to drive the sampling component. It can achieve sampling in different directions of different positions of the tumor tissue during a single puncture of the tumor tissue, thereby reducing the difficulty of sampling, and at the same time, does not require multiple punctures, thereby improving the efficiency of sampling and reducing the damage to the patient.

[0019] 2. The present invention, through the coordinated design of the sampling assembly and the needle tube, can pull the sampling tube into the interior below the needle tube after sampling is completed, and then seal the sampling tube, avoiding contamination of the sample by the external environment and ensuring the accuracy of the test results.

[0020] 3. The present invention, through the design of the suction component, when extracting samples, only one hand needs to hold the operating cylinder and use the thumb to drive the rotating wheel to rotate, and both left and right hands can operate, thereby realizing stable suction of samples with one hand, and the other hand can keep the patient's limb tumor tissue and the needle insertion site relatively stable, which is conducive to single-person sampling of tumor tissue. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;

[0022] Figure 2 It is a schematic diagram of the cross-sectional three-dimensional structure of the present invention;

[0023] Figure 3 It is a schematic diagram of the three-dimensional structure of the needle tube and the operating cylinder of the present invention when they are not installed;

[0024] Figure 4 It is a schematic diagram of the three-dimensional structure of the needle tube of the present invention;

[0025] Figure 5 It is a schematic diagram of the cutaway three-dimensional structure of the needle tube of the present invention;

[0026] Figure 6 It is a schematic diagram of a partially cutaway three-dimensional structure of a needle tube of the present invention;

[0027] Figure 7 This is an exploded view of the three-dimensional structure of the needle tube and the sampling assembly of the present invention;

[0028] Figure 8 The sectional view of the operating tube of the present invention is a schematic diagram of the three-dimensional structure Figure 1 ;

[0029] Fig. 9 The sectional view of the operating tube of the present invention is a schematic diagram of the three-dimensional structure Figure 2 ;

[0030] Fig.10 It is a schematic diagram of the partial three-dimensional structure of the suction component of the present invention.

[0031] Figure numerals: 1. needle tube; 2. wire slot; 3. connector; 4. operating cylinder; 5. sampling assembly; 51. sampling cylinder; 52. cylindrical groove; 53. round hole; 54. piston; 55. pull rod; 56. spiral pattern; 6. suction assembly; 61. turntable; 62. rotating cylinder; 63. spring; 64. gear ring; 65. threaded rod; 66. rotating wheel. DETAILED DESCRIPTION

[0032] To make the purpose, technical solution and advantages of the embodiments of the present invention more clear, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention.

[0033] A tumor tissue sampling device according to a preferred embodiment of the present invention will be described in detail below. Figure 1-Figure 4 As shown, a tumor tissue sampling device includes a needle tube 1, a wire groove 2 is opened on the top of the needle tube 1, the top of the needle tube 1 adopts a closed design, the wire groove 2 penetrates the outer wall of the needle tube 1, and the wire groove 2 is divided into two groups, the two groups of wire grooves 2 are arranged up and down on the top of the needle tube 1, and the two groups of wire grooves 2 are staggered and vertically distributed, the wire groove 2 is connected with the inside of the needle tube 1, and thus the wire groove 2 can be used to sample different positions and directions of the tumor tissue.

[0034] A connector 3 is fixedly installed on the periphery of the bottom of the needle tube 1, and an operating cylinder 4 is threadedly fixedly connected to the bottom of the needle tube 1. An internal thread is provided inside the bottom of the connector 3, and an external thread is provided on the periphery of the top of the operating cylinder 4. The threaded fixed connection between the needle tube 1 and the operating cylinder 4 is achieved by cooperating between the internal thread and the external thread. A sampling component 5 is arranged inside the operating cylinder 4, and a suction component 6 is arranged inside the operating cylinder 4. The suction component 6 is used to drive the sampling component 5 to sample tumor tissue.

[0035] Furthermore, if Figure 2 , Figure 4-Figure 7As shown, the sampling assembly 5 includes a sampling barrel 51, and the sampling barrel 51 is slidably connected to the top of the needle tube 1. Two cylindrical grooves 52 are symmetrically opened in the upper and lower parts of the sampling barrel 51. A circular hole 53 is opened at the top of the two cylindrical grooves 52 of the sampling barrel 51. The circular hole 53 penetrates the outer wall of the sampling barrel 51 and is connected with the cylindrical grooves 52. The circular holes 53 at the top of the two cylindrical grooves 52 are respectively aligned with the two groups of linear grooves 2 distributed above and below, so that the tumor tissue can enter the cylindrical groove 52 of the sampling barrel 51 through the linear grooves 2 and the circular holes 53.

[0036] The tops of the two cylindrical grooves 52 are both connected with pistons 54 in a limited sliding manner. When the pistons 54 are in the initial position at the tops of the cylindrical grooves 52, they can block the circular holes 53, so that the sampling tube 51 is in a closed state in the initial state. A pull rod 55 is fixedly installed at the center of the pistons 54. The pull rod 55 extends downward to the bottom of the connector 3. The pull rod 55 is used to pull the pistons 54 in the two cylindrical grooves 52 to move at the same time. A spiral pattern 56 is provided on the periphery of the lower half of the pull rod 55.

[0037] Furthermore, if Figure 2 , Figure 8-Figure 10 As shown, the suction assembly 6 includes a turntable 61, and the bottom limit rotation inside the operating cylinder 4 is connected to the turntable 61. When the needle tube 1 is installed, the pull rod 55 passes through the turntable 61 downward at the center of the spring 63, and the spiral pattern 56 of the pull rod 55 is threadedly connected to the turntable 61. Therefore, when the turntable 61 rotates, it can drive the pull rod 55 to move.

[0038] A rotating cylinder 62 is connected to the top of the rotating disk 61 in a limited rotation manner at the center of the top of the rotating disk 61, and a spring 63 is fixedly connected to the top of the rotating cylinder 62, so that the spring 63 and the rotating cylinder 62 can rotate at the top of the rotating disk 61. After the installation of the needle tube 1 and the operating cylinder 4 is completed, the spring 63 is squeezed and contacted with the bottom end of the sampling cylinder 51, so that after the installation is completed, under the action of the spring 63, the sampling cylinder 51 inside the needle tube 1 is located at the top of the needle tube 1.

[0039] A gear ring 64 is fixedly installed at the bottom end of the operating cylinder 4, and the gear ring 64 is concentric with the turntable 61. A threaded rod 65 is connected to the upper limit rotation of the gear ring 64 inside the operating cylinder 4, and the threaded rod 65 and the gear ring 64 are meshed with each other. Therefore, during the rotation of the threaded rod 65, the gear ring 64 and the turntable 61 can be driven to rotate. Both ends of the threaded rod 65 extend to the outside of the operating cylinder 4, and both ends of the threaded rod 65 are symmetrically fixed with rotating wheels 66 for driving the threaded rod 65 to rotate.

[0040] The working principle of the present invention is:

[0041] When installing the needle tube 1 and the operating cylinder 4, the connecting head 3 of the needle tube 1 is facing downward to insert the pull rod 55 into the operating cylinder 4. During the insertion process, the pull rod 55 passes downward through the center of the spring 63, and then the spiral pattern 56 under the pull rod 55 contacts the center of the turntable 61. Then, the needle tube 1 is rotated and the pull rod 55 is driven to rotate, so that the spiral pattern 56 under the pull rod 55 is threadedly connected with the center of the turntable 61 and gradually screwed downward until the connecting head 3 contacts the top of the operating cylinder 4. The needle tube 1 is continued to be rotated to make the connecting head 3 threadedly connected with the top of the operating cylinder 4, thereby completing the threaded fixed connection between the needle tube 1 and the operating cylinder 4 through the connecting head 3. At the same time, the spring 63 will also enter the interior of the needle tube 1 upward, and under the action of the spring 63, the sampling cylinder 51 is pushed to be located at the top of the inside of the needle tube 1.

[0042] When sampling is required, the needle tube 1 is inserted into the subcutaneous tumor tissue, and then the thumb is used to drive the rotating wheel 66 to rotate. The design of the rotating wheels 66 at both ends of the threaded rod 65 makes it easy for the left hand or the right hand to drive the rotating wheel 66 to rotate. During the rotation of the rotating wheel 66, the threaded rod 65 can be driven to rotate. The threaded rod 65 and the gear ring 64 are meshed with each other. During the rotation of the threaded rod 65, the gear ring 64 and the turntable 61 can be driven to rotate. The helical pattern 56 of the pull rod 55 is connected to the thread at the center of the turntable 61. During the rotation of the turntable 61, the pull rod 55 can be pulled downward to drive the piston 54. When the piston 54 moves downward inside the cylindrical groove 52, the penetrated tumor tissue can be sampled through the circular hole 53 and the wire groove 2 during the downward movement of the piston 54. In the process of the movement of the piston 54, the friction between the piston 54 and the sampling tube 51 can also be used to pull the compression spring 63 of the sampling tube 51 downward during the extraction process, so that the sampling tube 51 can pass through the circular hole 53 along the wire groove 2 for sampling. Through the distribution design of the wire groove 2, sampling can be achieved in different directions at different positions of the tumor tissue until the sampling tube 51 is pulled downward to the lower side of the lower wire groove 2, and the sampling tube 51 is sealed by the lower inner wall of the needle tube 1 to complete the sampling.

[0043] After completing the sampling, rotate the needle tube 1 in the opposite direction to disengage the connector 3 from the operating cylinder 4, and then continue to rotate the needle tube 1 in the opposite direction to disengage the spiral pattern 56 of the pull rod 55 from the turntable 61, thereby removing the needle tube 1. After completing the sampling and transferring to the detection environment, pull the pull rod 55 downward to remove the sample from the lower port of the needle tube 1 and perform the detection. When sampling is needed again, install the new needle tube 1 on the top of the operating cylinder 4.

[0044] The above description of the disclosed embodiments enables one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A tumor tissue sampling device, comprising a needle tube (1), characterized in that: The top of the needle tube (1) is provided with a wire groove (2), the outer periphery of the bottom of the needle tube (1) is fixedly mounted with a connector (3), the bottom of the needle tube (1) is threadedly fixedly connected with an operating cylinder (4), a sampling component (5) is arranged inside the operating cylinder (4), and a suction component (6) is arranged inside the operating cylinder (4), and the suction component (6) is used to drive the sampling component (5) to sample tumor tissue.

2. The tumor tissue sampling device according to claim 1, characterized in that: The top of the needle tube (1) adopts a closed design, the wire groove (2) penetrates the outer wall of the needle tube (1), and the wire groove (2) is divided into two groups, the two groups of wire grooves (2) are arranged vertically on the top of the needle tube (1), and the two groups of wire grooves (2) are staggered and vertically distributed, and the wire groove (2) is connected to the inside of the needle tube (1).

3. The tumor tissue sampling device according to claim 1, characterized in that: The bottom of the connector (3) is provided with an internal thread, and the top of the operating cylinder (4) is provided with an external thread. The needle tube (1) and the operating cylinder (4) are threadedly fixedly connected by the cooperation of the internal thread and the external thread.

4. The tumor tissue sampling device according to claim 1, characterized in that: The sampling assembly (5) comprises: A sampling tube (51), the top of the needle tube (1) is slidably connected to the sampling tube (51); Cylindrical grooves (52), wherein the interior of the sampling tube (51) is provided with two cylindrical grooves (52) symmetrically arranged in an upper and lower direction; A circular hole (53), wherein the top of the two cylindrical grooves (52) of the sampling tube (51) is provided with a circular hole (53); A piston (54), the tops of the two cylindrical grooves (52) are both limitedly slidably connected with the piston (54); A pull rod (55), a pull rod (55) is fixedly mounted at the center of the piston (54), and the pull rod (55) extends downward to the bottom of the connector (3); A spiral pattern (56) is provided on the periphery of the lower half of the pull rod (55).

5. The tumor tissue sampling device according to claim 4, characterized in that: The circular hole (53) passes through the outer wall of the sampling tube (51) and is connected to the cylindrical groove (52), and the circular holes (53) at the top of the two cylindrical grooves (52) are respectively aligned with the two groups of line grooves (2) distributed above and below.

6. The tumor tissue sampling device according to claim 4, characterized in that: When the piston (54) is at the initial position at the top of the cylindrical groove (52), the circular hole (53) can be blocked.

7. The tumor tissue sampling device according to claim 4, characterized in that: The suction assembly (6) comprises: A rotating disk (61), the bottom of the operating cylinder (4) is rotationally connected to the rotating disk (61); A rotating drum (62), the center of the top of the rotating disk (61) is connected to the rotating drum (62) in a limited rotation manner; A spring (63), the top of the rotating drum (62) is fixedly connected with the spring (63); A gear ring (64), the bottom end of the operating cylinder (4) is fixedly mounted with a gear ring (64), and the gear ring (64) is concentric with the rotating disk (61); A threaded rod (65), the upper part of the gear ring (64) inside the operating cylinder (4) is connected to the threaded rod (65) for limited rotation, and the threaded rod (65) and the gear ring (64) are meshed with each other; The two ends of the threaded rod (65) extend to the outside of the operating cylinder (4), and the two ends of the threaded rod (65) are symmetrically fixed with the wheels (66).

8. The tumor tissue sampling device according to claim 7, characterized in that: When the needle tube (1) is installed, the pull rod (55) passes through the turntable (61) downward at the center of the spring (63), and the helical pattern (56) of the pull rod (55) is threadedly connected to the turntable (61).

9. The tumor tissue sampling device according to claim 7, characterized in that: After the needle tube (1) and the operating cylinder (4) are installed, the spring (63) is pressed into contact with the bottom end of the sampling cylinder (51).

Images