Soothing, repairing and moisturizing face cream as well as preparation method and application thereof

Abstract

The invention discloses soothing, repairing and moisturizing face cream as well as a preparation method and application thereof. The soothing, repairing and moisturizing face cream is prepared from the following components in percentage by mass: 2.2 to 5.8 percent of soothing agent, 2.13 to 6.75 percent of repairing agent, 16 to 33 percent of moisturizing agent, 0.5 to 1 percent of thickening agent, 5.5 to 17 percent of emulsifying agent, 1 to 2 percent of preservative and the balance of water, the soothing agent is prepared from an opuntia ficus-indica fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil; the repairing agent is prepared from cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate. The repairing agent can repair skin barriers in a multi-level mode, the relieving agent can relieve skin sensitivity and redness, petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate form a protective layer outside the skin, and the action time of active ingredients is prolonged; secondly, by compounding different emulsifiers, the skin feeling problem in the use of the high petrolatum component is effectively solved, so that the excellent skin feeling and comfort of the face cream are maintained on the basis of the high petrolatum component.

Description

Technical Field

[0001] The invention relates to the technical field of cosmetics, and in particular to a soothing, repairing and moisturizing facial cream and a preparation method and application thereof. Background Art

[0002] With the increase of modern environmental pollution, climate change and life pressure, dry and sensitive skin problems are becoming more and more serious, manifested as dry skin, desquamation, itching, redness and allergies. Especially for people with allergic skin or susceptible skin, the stimulation of the skin by the external environment aggravates these discomforts, and the damage of the skin barrier function is an important reason for the recurrence of these symptoms. Therefore, in this case, how to restore the health of the skin barrier through effective repair and moisturizing measures has become a key issue that needs to be solved in the current skin care field.

[0003] Existing facial cream products usually relieve dryness and discomfort of the skin by combining a variety of moisturizing and repairing ingredients. However, many existing products have certain limitations in moisturizing and repairing effects, especially the formula design is difficult to strike a balance between moisturizing, repairing effects and comfort. These products often make the skin feel heavy or airtight, especially when using highly closed moisturizing ingredients such as petrolatum, which can effectively reduce water loss and form a protective layer on the skin surface due to its strong occlusive properties. However, this protective layer may also cause the skin's permeability to decrease, hinder the skin's natural detoxification and metabolism, and then cause skin problems such as acne and blackheads, especially on dry and sensitive skin. This uncomfortable skin feeling problem makes many consumers with dry and sensitive skin face a dilemma when choosing products: either sacrifice the moisturizing effect and choose a refreshing product; or choose a strong moisturizing product, but feel heavy and burdened during use.

[0004] In addition, although traditional repair ingredients, such as ceramide, hyaluronic acid, phytosphingosine, etc., can relieve dry skin and repair the skin barrier to a certain extent, their lack of permeability is still a major problem. Many repair ingredients stay on the surface of the skin and cannot effectively penetrate into the deep layers of the skin, resulting in the inability to truly exert the repair effect, thus affecting their ability to repair the skin barrier, relieve redness and allergic reactions.

[0005] Therefore, in the care of dry and sensitive skin, balancing moisturizing and repairing effects while satisfying a good skin feel is the core challenge in developing an effective facial cream. Summary of the invention

[0006] In view of the above-mentioned prior art, the purpose of the present invention is to provide a soothing, repairing and moisturizing facial cream and its preparation method and application. The present invention repairs the skin barrier at multiple levels by compounding cholesterol, ceramide NP, ceramide AP, sodium hyaluronate, phytosphingosine, and tetraacetyl phytosphingosine. Dipotassium glycyrrhizinate, bisabolol, white meadowfoam seed oil, and fairy peach cactus fruit extract soothe skin sensitive redness reaction. Petrolatum, glycerin, caprylic / capric triglyceride, and isononyl isononanoate form a protective layer outside the skin, effectively moisturizing and delaying the volatilization of active ingredients, and prolonging the action time of active ingredients. Secondly, the present invention compounds different emulsifiers and precisely matches Lipomulse Luxe MB, Emulsifiers such as 1000, RFA C1618 and glyceryl stearate SE effectively solve the skin feel problem in the use of high petrolatum ingredients, thereby maintaining the excellent skin feel and comfort of the cream on the basis of high petrolatum ingredients. The soothing and repairing oil cream suitable for sensitive skin of the present invention has a stable structure, good permeability, and is easy to absorb. It effectively delivers the repairing and soothing ingredients to the deep layer of the skin, repairs the skin barrier, fades redness and soothes, and has good moisturizing effects.

[0007] To achieve the above object, the present invention adopts the following technical solution:

[0008] The first aspect of the present invention provides a soothing, repairing and moisturizing facial cream, comprising the following components in percentage by weight:

[0009] Soothing agent 2.2-5.8%, repairing agent 2.13-6.75%, moisturizing agent 16-33%, thickening agent 0.5-1%, emulsifier 5.5-17%, preservative 1-2%, the balance is water;

[0010] The soothing agent is composed of Opuntia ficus-indica fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil in a mass ratio of (1-2): (0.1-0.3): (0.1-0.5): (1-3);

[0011] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of (1-3): (1-3): (0.01-0.1): (0.01-0.1): (0.01-0.05): (0.1-0.5).

[0012] Preferably, the moisturizer is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of (7-15):(3-6):(3-6):(3-6).

[0013] Preferably, the emulsifier is Lipomulse Luxe MB, 1000, RFA C1618 and glyceryl stearate SE are composed in the mass ratio of (2-5):(2-5):(1-4):(0.5-3).

[0014] Preferably, the Lipomulse Luxe MB comprises the following components in percentage by mass: 54% of cetearyl alcohol, 30% of glyceryl stearate, 12% of PEG-40 stearate and 4% of ceteareth-20.

[0015] Preferably, the 1000 includes the following components in percentage by mass: 60% of cetearyl olivate and 40% of sorbitan olivate.

[0016] Preferably, the RFA C1618 comprises the following components in percentage by mass: 70% stearyl alcohol and 30% cetyl alcohol.

[0017] Preferably, the thickener is ammonium acryloyldimethyltaurate / VP copolymer.

[0018] Preferably, the preservative is htsoft-5688, which includes the following components in percentage by mass: 51% dipropylene glycol, 27% p-hydroxyacetophenone, 11% 1,2-hexanediol, 8% caprylyl glycol, and 3% isoprene glycol.

[0019] The second aspect of the present invention provides a method for preparing the soothing, repairing and moisturizing facial cream, comprising the following steps:

[0020] (1) Heat water to 80-85° C., add glycerin, thickener, sodium hyaluronate, and dipotassium glycyrrhizinate, and homogenize and disperse evenly to form an aqueous phase;

[0021] (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, Lipomulse TM Luxe MB, 1000, RFA C1618, cholesterol, ceramide NP, glyceryl stearate SE, meadowfoam seed oil, opuntia cactus fruit extract, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine were mixed evenly, heated to 80-85°C, and stirred until the raw materials were completely dissolved to form an oil phase;

[0022] (3) Slowly pour the oil phase into the water phase while turning on the homogenizer until the emulsification is uniform;

[0023] (4) Cool down to 40-45° C., add preservatives and bisabolol in sequence, and stir evenly to obtain a soothing, repairing and moisturizing facial cream.

[0024] The third aspect of the present invention provides use of the soothing, repairing and moisturizing facial cream in the preparation of soothing, repairing and moisturizing products.

[0025] Beneficial effects of the present invention:

[0026] (1) The present invention repairs the skin barrier at multiple levels by compounding cholesterol, ceramide NP, ceramide AP, sodium hyaluronate, phytosphingosine, and tetraacetyl phytosphingosine; dipotassium glycyrrhizinate, bisabolol, white meadowfoam seed oil, and fairy peach cactus fruit extract soothe skin sensitive redness reaction; petrolatum, glycerin, caprylic / capric triglyceride, and isononyl isononanoate form a protective layer outside the skin, effectively moisturizing and delaying the volatilization of active ingredients, thereby prolonging the action time of active ingredients; secondly, the present invention compounded different emulsifiers, and precisely matched Lipomulse Luxe MB, Emulsifiers such as 1000, RFA C1618 and glyceryl stearate SE effectively solve the skin feel problem in the use of high petrolatum ingredients, thereby maintaining the excellent skin feel and comfort of the cream on the basis of high petrolatum ingredients. The soothing and repairing oil cream suitable for sensitive skin of the present invention has a stable structure, good permeability, and is easy to absorb. It effectively delivers the repairing and soothing ingredients to the deep layer of the skin, repairs the skin barrier, fades redness and soothes, and has good moisturizing effects.

[0027] (2) The present invention precisely matches Lipomuls Luxe MB, Emulsifiers such as 1000, RFA C1618 and glyceryl stearate SE. Lipomulse Luxe MB is a highly effective emulsifier that can form a stable water-oil emulsion structure in the cream and has a good skin feel, so that the final formula can not only effectively and evenly disperse petrolatum, but also provide a smooth and silky touch, reducing the heaviness and stuffiness that petrolatum may bring; As a natural plant-derived emulsifier, RFA 1000 has excellent hydrophilicity and lipophilicity, which can help the ingredients penetrate deeply and improve the permeability of the product, ensuring that petrolatum and other active ingredients can be effectively absorbed by the skin. In addition, C1618 has excellent stability and low irritation, and can enhance the stability of the emulsifier in compounding, further improve the texture of the cream, reduce the greasy feeling, and thus optimize the overall skin feel. Finally, as a high-quality emulsifier, glyceryl stearate SE can improve the touch of the skin, make the cream smoother, and has good skin adaptability. In the formula with high petrolatum ingredients, it can further optimize the use experience of the cream and reduce the heavy feeling or airtightness that may be caused by the petrolatum ingredients. Through the fine proportions of these emulsifiers, the present invention ensures that the product has good permeability and comfortable skin feel even when a high concentration of petrolatum is added. The efficient moisturizing effect of petrolatum is retained, while avoiding the dull feeling that may be caused by traditional petrolatum moisturizing ingredients. Finally, the application of the compound emulsifier enables the product to achieve an ideal balance in moisturizing, repairing and skin feel, providing a better care experience for dry and sensitive skin.

[0028] (3) The soothing, repairing and moisturizing facial cream of the present invention has a stable structure, good permeability, and is easily absorbed. It can effectively deliver the repairing and soothing ingredients to the deep layers of the skin, repair the skin barrier, reduce redness and soothe, and has good moisturizing effects. In addition, the preparation method of the present invention is simple, the conditions are controllable, the process is stable, and it can be promoted and applied. DETAILED DESCRIPTION

[0029] It should be noted that the following detailed descriptions are illustrative and are intended to provide further explanation of the present application. Unless otherwise specified, all technical and scientific terms used herein have the same meanings as those commonly understood by those skilled in the art to which the present application belongs.

[0030] In order to enable those skilled in the art to more clearly understand the technical solution of the present application, the technical solution of the present application will be described in detail below in conjunction with specific embodiments.

[0031] The test materials used in the examples of the present invention are all conventional test materials in the art and can be purchased through commercial channels.

[0032] Wherein, the components and manufacturers used in the present invention are as follows:

[0033] Table 1 Reagents used and manufacturers

[0034]

[0035]

[0036] Example 1: Preparation of soothing, repairing and moisturizing facial cream:

[0037] 1. Raw material composition:

[0038] Soothing agent 3.3%, repairing agent 4.36%, moisturizing agent 24%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 9%, htsoft-5688 1%, the balance is water;

[0039] The soothing agent is composed of opuntia cactus fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil in a mass ratio of 1.5:0.1:0.2:1.5;

[0040] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 2:2:0.1:0.05:0.01:0.2;

[0041] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 10:4:5:5;

[0042] The emulsifier is composed of Lipomulse Luxe MB, 1000, RFA C1618 and glyceryl stearate SE are composed in a mass ratio of 3:3:2:1.

[0043] 2. Preparation method:

[0044] (1) heating water to 85° C., adding glycerin, ammonium acryloyldimethyltaurate / VP copolymer, sodium hyaluronate, and dipotassium glycyrrhizinate during the heating process, and homogenizing and dispersing the mixture to form an aqueous phase;

[0045] (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, Lipomulse TM Luxe MB, 1000, RFA C1618, cholesterol, ceramide NP, glyceryl stearate SE, meadowfoam seed oil, opuntia cactus fruit extract, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine were mixed evenly, heated to 85°C, and stirred until the raw materials were completely dissolved to form an oil phase;

[0046] (3) Slowly pour the oil phase into the water phase while homogenizing until the emulsification is uniform;

[0047] (4) Cool down to 45°C, add htsoft-5688 and bisabolol in sequence, and stir evenly to obtain a soothing, repairing and moisturizing facial cream.

[0048] Example 2: Preparation of soothing, repairing and moisturizing facial cream:

[0049] 1. Raw material composition:

[0050] Soothing agent 2.22%, repairing agent 2.29%, moisturizing agent 24%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 9%, htsoft-5688 1%, the balance is water;

[0051] The soothing agent is composed of opuntia cactus fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil in a mass ratio of 1:0.11:0.11:1;

[0052] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 1:1:0.05:0.03:0.01:0.2;

[0053] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 10:4:5:5;

[0054] The emulsifier is composed of Lipomulse Luxe MB, 1000, RFA C1618 and glyceryl stearate SE are composed in a mass ratio of 3:3:2:1.

[0055] The preparation method is the same as that of Example 1 to prepare a soothing, repairing and moisturizing facial cream.

[0056] Example 3: Preparation of soothing, repairing and moisturizing facial cream:

[0057] 1. Raw material composition:

[0058] Soothing agent 2.2%, repairing agent 2.13%, moisturizing agent 16%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 5.5%, htsoft-5688 1%, the balance is water;

[0059] The soothing agent is composed of opuntia cactus fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil in a mass ratio of 1:0.1:0.1:1;

[0060] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 1:1:0.01:0.01:0.01:0.1;

[0061] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 7:3:3:3;

[0062] The emulsifier is composed of Lipomulse Luxe MB, 1000, RFA C1618 and glyceryl stearate SE are composed in a mass ratio of 2:2:1:0.5.

[0063] The preparation method is the same as that of Example 1 to prepare a soothing, repairing and moisturizing facial cream.

[0064] Example 4: Preparation of soothing, repairing and moisturizing facial cream:

[0065] 1. Raw material composition:

[0066] Soothing agent 5.8%, repairing agent 6.75%, moisturizing agent 33%, ammonium acryloyldimethyltaurate / VP copolymer 1%, emulsifier 17%, htsoft-5688 2%, the balance is water;

[0067] The soothing agent is composed of opuntia cactus fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil in a mass ratio of 2:0.3:0.5:3;

[0068] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 3:3:0.1:0.1:0.05:0.5;

[0069] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 15:6:6:6;

[0070] The emulsifier is composed of Lipomulse Luxe MB, 1000, RFA C1618 and glyceryl stearate SE are composed in a mass ratio of 5:5:4:3.

[0071] The preparation method is the same as that of Example 1 to prepare a soothing, repairing and moisturizing facial cream.

[0072] Comparative Example 1:

[0073] 1. Raw material composition:

[0074] Soothing agent 3.3%, repairing agent 4.36%, moisturizing agent 24%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 9%, htsoft-5688 1%, the balance is water;

[0075] The soothing agent is an extract of Opuntia cactus fruit;

[0076] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 2:2:0.1:0.05:0.01:0.2;

[0077] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 10:4:5:5;

[0078] The emulsifier is composed of Lipomulse Luxe MB, 1000, RFA C1618 and glyceryl stearate SE are composed in a mass ratio of 3:3:2:1.

[0079] 2. Preparation method:

[0080] (1) heating water to 85° C., adding glycerin, ammonium acryloyldimethyltaurate / VP copolymer, and sodium hyaluronate during the heating process, and homogenizing and dispersing them evenly to form an aqueous phase;

[0081] (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, Lipomulse TM Luxe MB, 1000, RFA C1618, cholesterol, ceramide NP, glyceryl stearate SE, Xiantao cactus fruit extract, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine were mixed evenly, heated to 85°C, and stirred until the raw materials were completely dissolved to form an oil phase;

[0082] (3) Slowly pour the oil phase into the water phase while turning on the homogenizer until the emulsification is uniform;

[0083] (4) Cool down to 45°C, add htsoft-5688 in sequence, stir evenly, and obtain a facial cream.

[0084] The difference between this comparative example and Example 1 is that the soothing agent is a single extract of Opuntia cactus fruit.

[0085] Comparative Example 2:

[0086] 1. Raw material composition:

[0087] Soothing agent 3.3%, repairing agent 4.36%, moisturizing agent 24%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 9%, htsoft-5688 1%, the balance is water;

[0088] The soothing agent is dipotassium glycyrrhizinate;

[0089] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 2:2:0.1:0.05:0.01:0.2;

[0090] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 10:4:5:5;

[0091] The emulsifier is composed of Lipomulse Luxe MB, 1000, RFA C1618 and glyceryl stearate SE are composed in a mass ratio of 3:3:2:1.

[0092] 2. Preparation method:

[0093] (1) heating water to 85° C., adding glycerin, ammonium acryloyldimethyltaurate / VP copolymer, sodium hyaluronate, and dipotassium glycyrrhizinate during the heating process, and homogenizing and dispersing the mixture to form an aqueous phase;

[0094] (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, Lipomulse TM Luxe MB, 1000, RFA C1618, cholesterol, ceramide NP, glyceryl stearate SE, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine were mixed evenly, heated to 85°C, and stirred until the raw materials were completely dissolved to form an oil phase;

[0095] (3) Slowly pour the oil phase into the water phase while homogenizing until the emulsification is uniform;

[0096] (4) Cool down to 45°C, add htsoft-5688 in sequence, stir evenly, and obtain a facial cream.

[0097] The difference between this comparative example and Example 1 is that the soothing agent is a single dipotassium glycyrrhizinate.

[0098] Comparative Example 3:

[0099] 1. Raw material composition:

[0100] Soothing agent 3.3%, repairing agent 4.36%, moisturizing agent 24%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 9%, htsoft-5688 1%, the balance is water;

[0101] The soothing agent is bisabolol;

[0102] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 2:2:0.1:0.05:0.01:0.2;

[0103] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 10:4:5:5;

[0104] The emulsifier is composed of Lipomulse Luxe MB, 1000, RFA C1618 and glyceryl stearate SE are composed in a mass ratio of 3:3:2:1.

[0105] 2. Preparation method:

[0106] (1) heating water to 85° C., adding glycerin, ammonium acryloyldimethyltaurate / VP copolymer, and sodium hyaluronate during the heating process, and homogenizing and dispersing them evenly to form an aqueous phase;

[0107] (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, Lipomulse TM Luxe MB, 1000, RFA C1618, cholesterol, ceramide NP, glyceryl stearate SE, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine were mixed evenly, heated to 85°C, and stirred until the raw materials were completely dissolved to form an oil phase;

[0108] (3) Slowly pour the oil phase into the water phase while homogenizing until the emulsification is uniform;

[0109] (4) Cooling to 45° C., adding htsoft-5688 and bisabolol in sequence, stirring evenly, and obtaining a facial cream.

[0110] The difference between this comparative example and Example 1 is that the soothing agent is single bisabolol.

[0111] Comparative Example 4:

[0112] 1. Raw material composition:

[0113] Soothing agent 3.3%, repairing agent 4.36%, moisturizing agent 24%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 9%, htsoft-5688 1%, the balance is water;

[0114] The soothing agent is meadowfoam seed oil;

[0115] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 2:2:0.1:0.05:0.01:0.2;

[0116] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 10:4:5:5;

[0117] The emulsifier is composed of Lipomulse Luxe MB, 1000, RFA C1618 and glyceryl stearate SE are composed in a mass ratio of 3:3:2:1.

[0118] 2. Preparation method:

[0119] (1) heating water to 85° C., adding glycerin, ammonium acryloyldimethyltaurate / VP copolymer, and sodium hyaluronate during the heating process, and homogenizing and dispersing them evenly to form an aqueous phase;

[0120] (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, Lipomulse TM Luxe MB, 1000, RFA C1618, cholesterol, ceramide NP, glyceryl stearate SE, meadowfoam seed oil, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine were mixed evenly, heated to 85°C, and stirred until the raw materials were completely dissolved to form an oil phase;

[0121] (3) Slowly pour the oil phase into the water phase while turning on the homogenizer until the emulsification is uniform;

[0122] (4) Cool down to 45°C, add htsoft-5688 in sequence, stir evenly, and obtain a facial cream.

[0123] The difference between this comparative example and Example 1 is that the soothing agent is single meadowfoam seed oil.

[0124] Comparative Example 5:

[0125] 1. Raw material composition:

[0126] Repair agent 4.36%, moisturizer 24%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 9%, htsoft-5688 1%, the balance is water;

[0127] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 2:2:0.1:0.05:0.01:0.2;

[0128] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 10:4:5:5;

[0129] The emulsifier is composed of Lipomulse Luxe MB, 1000, RFA C1618 and glyceryl stearate SE are composed in a mass ratio of 3:3:2:1.

[0130] 2. Preparation method:

[0131] (1) heating water to 85° C., adding glycerin, ammonium acryloyldimethyltaurate / VP copolymer, and sodium hyaluronate during the heating process, and homogenizing and dispersing them evenly to form an aqueous phase;

[0132] (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, Lipomulse TM Luxe MB, 1000, RFA C1618, cholesterol, ceramide NP, glyceryl stearate SE, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine were mixed evenly, heated to 85°C, and stirred until the raw materials were completely dissolved to form an oil phase;

[0133] (3) Slowly pour the oil phase into the water phase while turning on the homogenizer until the emulsification is uniform;

[0134] (4) Cool down to 45°C, add htsoft-5688 in sequence, stir evenly, and obtain a facial cream.

[0135] The difference between this comparative example and Example 1 is that the soothing agent is omitted.

[0136] Comparative Example 6:

[0137] 1. Raw material composition:

[0138] Soothing agent 3.3%, repairing agent 4.36%, moisturizing agent 24%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 9%, htsoft-5688 1%, the balance is water;

[0139] The soothing agent is composed of opuntia cactus fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil in a mass ratio of 1.5:0.1:0.2:1.5;

[0140] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 2:2:0.1:0.05:0.01:0.2;

[0141] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 10:4:5:5;

[0142] The emulsifier is composed of Lipomulse Luxe MB and 1000 is composed in a mass ratio of 3:3.

[0143] 2. Preparation method:

[0144] (1) heating water to 85° C., adding glycerin, ammonium acryloyldimethyltaurate / VP copolymer, sodium hyaluronate, and dipotassium glycyrrhizinate during the heating process, and homogenizing and dispersing the mixture to form an aqueous phase;

[0145] (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, Lipomulse TM Luxe MB, cholesterol, ceramide NP, meadowfoam seed oil, opuntia cactus fruit extract, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine are mixed evenly, heated to 85° C., and stirred until the raw materials are completely dissolved to form an oil phase;

[0146] (3) Slowly pour the oil phase into the water phase while turning on the homogenizer until the emulsification is uniform;

[0147] (4) Cooling to 45° C., adding htsoft-5688 and bisabolol in sequence, stirring evenly, and obtaining a facial cream.

[0148] The difference between this comparative example and Example 1 is that the emulsifier is Lipomulse Luxe MB and 1000.

[0149] Comparative Example 7:

[0150] 1. Raw material composition:

[0151] Soothing agent 3.3%, repairing agent 4.36%, moisturizing agent 24%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 9%, htsoft-5688 1%, the balance is water;

[0152] The soothing agent is composed of opuntia cactus fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil in a mass ratio of 1.5:0.1:0.2:1.5;

[0153] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 2:2:0.1:0.05:0.01:0.2;

[0154] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 10:4:5:5;

[0155] The emulsifier is composed of Lipomulse Luxe MB and RFA C1618 in a mass ratio of 3:2.

[0156] 2. Preparation method:

[0157] (1) heating water to 85° C., adding glycerin, ammonium acryloyldimethyltaurate / VP copolymer, sodium hyaluronate, and dipotassium glycyrrhizinate during the heating process, and homogenizing and dispersing the mixture to form an aqueous phase;

[0158] (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, 1000, cholesterol, ceramide NP, meadowfoam seed oil, opuntia cactus fruit extract, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine are mixed evenly, heated to 85° C., and stirred until the raw materials are completely dissolved to form an oil phase;

[0159] (3) Slowly pour the oil phase into the water phase while homogenizing until the emulsification is uniform;

[0160] (4) Cooling to 45° C., adding htsoft-5688 and bisabolol in sequence, stirring evenly, and obtaining a facial cream.

[0161] The difference between this comparative example and Example 1 is that the emulsifiers are Lipomulse Luxe MB and RFA C1618.

[0162] Comparative Example 8:

[0163] 1. Raw material composition:

[0164] Soothing agent 3.3%, repairing agent 4.36%, moisturizing agent 24%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 9%, htsoft-5688 1%, the balance is water;

[0165] The soothing agent is composed of opuntia cactus fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil in a mass ratio of 1.5:0.1:0.2:1.5;

[0166] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 2:2:0.1:0.05:0.01:0.2;

[0167] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 10:4:5:5;

[0168] The emulsifier is composed of Lipomulse Luxe MB and glyceryl stearate SE in a mass ratio of 3:1.

[0169] 2. Preparation method:

[0170] (1) heating water to 85° C., adding glycerin, ammonium acryloyldimethyltaurate / VP copolymer, sodium hyaluronate, and dipotassium glycyrrhizinate during the heating process, and homogenizing and dispersing the mixture to form an aqueous phase;

[0171] (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, RFA C1618, cholesterol, ceramide NP, meadowfoam seed oil, opuntia cactus fruit extract, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine are mixed evenly, heated to 85° C., and stirred until the raw materials are completely dissolved to form an oil phase;

[0172] (3) Slowly pour the oil phase into the water phase while homogenizing until the emulsification is uniform;

[0173] (4) Cooling to 45° C., adding htsoft-5688 and bisabolol in sequence, stirring evenly, and obtaining a facial cream.

[0174] The difference between this comparative example and Example 1 is that the emulsifiers are Lipomulse Luxe MB and glyceryl stearate SE.

[0175] Comparative Example 9:

[0176] 1. Raw material composition:

[0177] Soothing agent 3.3%, repairing agent 4.36%, moisturizing agent 24%, ammonium acryloyldimethyltaurate / VP copolymer 0.5%, emulsifier 9%, htsoft-5688 1%, the balance is water;

[0178] The soothing agent is composed of opuntia cactus fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil in a mass ratio of 1.5:0.1:0.2:1.5;

[0179] The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of 2:2:0.1:0.05:0.01:0.2;

[0180] The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of 10:4:5:5;

[0181] The emulsifier is Lipomulse Luxe MB.

[0182] 2. Preparation method:

[0183] (1) heating water to 85° C., adding glycerin, ammonium acryloyldimethyltaurate / VP copolymer, sodium hyaluronate, and dipotassium glycyrrhizinate during the heating process, and homogenizing and dispersing the mixture to form an aqueous phase;

[0184] (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, cholesterol, ceramide NP, glyceryl stearate SE, meadowfoam seed oil, opuntia cactus fruit extract, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine are mixed evenly, heated to 85° C., and stirred until the raw materials are completely dissolved to form an oil phase;

[0185] (3) Slowly pour the oil phase into the water phase while homogenizing until the emulsification is uniform;

[0186] (4) Cooling to 45° C., adding htsoft-5688 and bisabolol in sequence, stirring evenly, and obtaining a facial cream.

[0187] The difference between this comparative example and Example 1 is that the emulsifier is a single Lipomulse Luxe MB.

[0188] Test Example 1: Human efficacy evaluation:

[0189] A human efficacy test evaluation method was adopted, and the subjects were selected: 90 male and female subjects aged 24-37 years old were selected. The subjects were in good health and self-assessed as having sensitive skin, which met the voluntary selection criteria for the subjects.

[0190] Test instrument: Cotometer MPA580 host manufactured by Courage + Khazaka (CK) of Germany;

[0191] Testing location: 6th Floor, Building 3, Boco Headquarters, Gangxingyuan Road, Licheng District, Jinan City, Shandong Province;

[0192] Test environment: temperature 21.0℃±1℃, relative humidity 50%±10%RH;

[0193] Test process: Take the soothing and repairing moisturizing cream prepared in Examples 1-4 and the cream prepared in Comparative Examples 1-5 as samples, divide 90 subjects into 9 groups, each with 10 subjects, use the products of different embodiments and comparative examples respectively, first measure the blank value 30 minutes after the tested area is cleaned, then require the subjects to insist on using the above test products every morning and evening, and test the transepidermal water loss rate and skin hemoglobin value of the tested area after 14 days and 28 days of use respectively.

[0194] 1. Determination of transepidermal water loss rate

[0195] Determination basis: T / ZHCA 003—2018 Test method for the effect of cosmetics on transepidermal water loss;

[0196] Test method: Cotometer MPA580 manufactured by Courage+Khazaka (CK) of Germany was used, and the probe used was Tewameter TM Hex transepidermal water loss and heat loss test probe. The average value was taken after five measurements. The blank value was measured 30 minutes after the test area was cleaned, and then the subjects were required to use the above test products every morning and evening, and the transepidermal water loss rate of the test area was tested after 14 days and 28 days of use.

[0197] Indicator explanation: The smaller the transepidermal water loss rate of the skin, the better the skin's barrier function.

[0198] Transepidermal water loss rate (%) = [(transepidermal water loss rate after trial - transepidermal water loss rate before trial) / transepidermal water loss rate before trial] × 100%.

[0199] 2. Hemoglobin value determination experiment

[0200] Judgment basis: T / CNMIA 0015-2020 Clinical Evaluation Standards for Allergy-Relief Functional Skin Care Products

[0201] Test method: The Cotometer MPA580 host manufactured by Courage + Khazaka (CK) of Germany was used, and the probe used was the Mexameter MX18 melanin and red pigment test probe. The average value was taken after five measurements. The blank value was first measured 30 minutes after the test area was cleaned, and then the subjects were required to use the above test products every morning and evening, and the skin hemoglobin value of the test area was tested after 14 days and 28 days of use.

[0202] Indicator description: The smaller the skin hemoglobin value, the more obvious the improvement of skin redness, and the better the soothing effect of the sample.

[0203] Hemoglobin value change rate % = [(hemoglobin value after trial - hemoglobin value before trial) / hemoglobin value before trial] × 100%.

[0204] 3. Test results:

[0205] Table 2 Transepidermal moisture change rate under different treatments

[0206] 14-day transepidermal water change rate (%) 28-day transepidermal water change rate (%) Example 1 -29.23 -48.33 Example 2 -22.28 -41.42 Example 3 -25.73 -48.82 Example 4 -22.31 -40.69 Comparative Example 1 -14.26 -20.63 Comparative Example 2 -16.78 -23.23 Comparative Example 3 -17.16 -28.77 Comparative Example 4 -15.77 -19.76 Comparative Example 5 -12.14 -18.79

[0207] As shown in Table 2, the transepidermal moisture change rate test results show that the soothing, repairing and moisturizing creams prepared in Examples 1-4 of the present invention have good repairing effects.

[0208] Table 3 Changes in skin hemoglobin values ​​after using different facial creams

[0209]

[0210]

[0211] As shown in Table 3, the hemoglobin value test results show that the soothing, repairing and moisturizing facial creams prepared in Examples 1-4 of the present invention have good soothing effects.

[0212] Test Example 2: Hyaluronidase inhibition rate experiment

[0213] Take the soothing, repairing and moisturizing facial creams prepared in Examples 1-4 and the facial creams prepared in Comparative Examples 1-5 as samples;

[0214] Testing environment: temperature 21.0℃±1℃, relative humidity 50%±10%RH, other conditions are in accordance with standard requirements;

[0215] Testing location: 6th Floor, Building 3, Boco Headquarters, Gangxingyuan Road, Licheng District, Jinan City, Shandong Province;

[0216] Determination basis: laboratory method (hyaluronidase inhibition rate);

[0217] This test determines whether a sample has a soothing effect by testing its ability to inhibit hyaluronidase.

[0218] Experimental methods:

[0219] S1 sample pretreatment (5-fold dilution with water);

[0220] S2 sample was reacted with sodium hyaluronate enzyme;

[0221] S3 reactant color development;

[0222] S4 measured absorbance at 530 nm;

[0223] S5 Calculate the hyaluronidase inhibition rate.

[0224] The calculation formula of hyaluronidase inhibition rate is:

[0225]

[0226] Wherein: A is the absorbance of the control group (acetate buffer replaces the test sample); B is the absorbance of the blank group (acetate buffer replaces the enzyme solution and the test sample); C is the absorbance of the experimental group; D is the absorbance of the sample blank group (acetate buffer replaces the enzyme solution).

[0227] Table 4 Hyaluronidase inhibition rate of different samples

[0228] deal with Hyaluronidase inhibition rate (%) Example 1 70.53 Example 2 69.31 Example 3 69.44 Example 4 71.39 Comparative Example 1 40.67 Comparative Example 2 45.98 Comparative Example 3 49.26 Comparative Example 4 38.27 Comparative Example 5 34.78

[0229] As shown in Table 4, in Example 1, the extract of Opuntia cactus fruit, dipotassium glycyrrhizinate, bisabolol and white meadowfoam seed oil are compounded in a mass ratio of 1.5:0.1:0.2:1.5 as a soothing agent, and the prepared soothing repair moisturizing cream has an inhibition rate of 70.53% on hyaluronidase. In Comparative Example 5, no soothing agent is added, and the inhibition rate of hyaluronidase is 34.78%. Comparative Examples 1-4 respectively add single Opuntia cactus fruit extract, dipotassium glycyrrhizinate, bisabolol and white meadowfoam seed oil on the basis of Comparative Example 5. The oil is used as a soothing agent. Compared with comparative example 5, the hyaluronidase inhibition rate is increased by 5.89%, 11.2%, 14.48% and 3.49%, respectively. Compared with comparative example 5, the total increase in the hyaluronidase inhibition rate of comparative examples 1-4 is 35.06%, and the total increase in the hyaluronidase inhibition rate of the rubber comparative example 5 of Example 1 is 35.75%, indicating that the compounding of the peach cactus fruit extract, dipotassium glycyrrhizate, bisabolol and white meadowfoam seed oil in the present invention has a synergistic effect on improving the hyaluronidase inhibition rate.

[0230] Test Example 3: Skin Feel Evaluation

[0231] A total of 30 subjects were selected for the questionnaire survey, and there were 30 valid subjects, with an age range of 24-37 years old and an average age of 29 years old. The subjects had healthy skin and no history of skin allergies, meeting the voluntary selection criteria for the subjects; all 30 subjects used the creams prepared in Example 1 and Comparative Examples 6-9 every morning and evening, and the specific operations were as follows:

[0232] After cleaning the skin, select a cream prepared in Example 1 and Comparative Examples 6-9 and apply it evenly on half of the cheek until it is completely absorbed; after completion, apply another cream on the other half of the cheek and repeat the above steps. Record the use experience in real time during the application process; each person uses two creams every day for the first two days, and tests one cream on the third day, for a total of three days. Fill out the questionnaire after use.

[0233] Scoring criteria: 7 points for very agree, 6 points for relatively agree, 5 points for somewhat agree, 4 points for neither agree nor disagree, 3 points for somewhat disagree, 2 points for relatively disagree, and 1 point for very disagree.

[0234] Table 5 Questionnaire survey results of subjects (average score)

[0235] Evaluation Metrics Example 1 Comparative Example 6 Comparative Example 7 Comparative Example 8 Comparative Example 9 Strong moisturizing feeling 6.5 5.8 5.5 5.3 5.1 Smooth, easy to apply evenly 6.3 4.4 5.0 4.2 4.0 Not heavy, not dull 6.1 3.9 4.1 4.0 3.8 Rapid skin absorption 6.5 5.0 4.8 4.6 4.4 Non-sticky 6.5 4.4 4.4 4.2 4.0

[0236] As shown in Table 5, the skin feel evaluation shows that the present invention combines Lipomulse Luxe MB, 1000, RFAC1618 and glyceryl stearate SE are compounded to prepare a facial cream that is quickly absorbed by the skin and is not thick, dull or sticky, which significantly improves the skin feel of the facial cream.

[0237] The above description is only the preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A soothing, repairing and moisturizing facial cream, characterized in that: The following components are included in mass percentage: Soothing agent 2.2-5.8%, repairing agent 2.13-6.75%, moisturizing agent 16-33%, thickening agent 0.5-1%, emulsifier 5.5-17%, preservative 1-2%, the balance is water; The soothing agent is composed of Opuntia ficus-indica fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil in a mass ratio of (1-2): (0.1-0.3): (0.1-0.5): (1-3); The repair agent is composed of cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate in a mass ratio of (1-3): (1-3): (0.01-0.1): (0.01-0.1): (0.01-0.05): (0.1-0.5).

2. The soothing, repairing and moisturizing facial cream according to claim 1, characterized in that: The moisturizing agent is composed of petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate in a mass ratio of (7-15):(3-6):(3-6):(3-6).

3. The soothing, repairing and moisturizing facial cream according to claim 2, characterized in that: The emulsifier is composed of LipomulseLuxe MB, 1000, RFA C1618 and glyceryl stearate SE are composed in the mass ratio of (2-5):(2-5):(1-4):(0.5-3).

4. The soothing, repairing and moisturizing facial cream according to claim 3, characterized in that: The Lipomulse Luxe MB comprises the following components in percentage by mass: 54% of cetearyl alcohol, 30% of glyceryl stearate, 12% of PEG-40 stearate and 4% of ceteareth-20.

5. The soothing, repairing and moisturizing facial cream according to claim 3, characterized in that: Said 1000 includes the following components in percentage by mass: 60% of cetearyl olivate and 40% of sorbitan olivate.

6. The soothing, repairing and moisturizing facial cream according to claim 3, characterized in that: The RFA C1618 comprises the following components in percentage by mass: 70% stearyl alcohol and 30% cetyl alcohol.

7. The soothing, repairing and moisturizing facial cream according to claim 1, characterized in that: The thickener is ammonium acryloyldimethyltaurate / VP copolymer.

8. The soothing, repairing and moisturizing facial cream according to claim 1, characterized in that: The preservative is htsoft-5688, which includes the following components in percentage by mass: 51% of dipropylene glycol, 27% of p-hydroxyacetophenone, 11% of 1,2-hexanediol, 8% of caprylyl glycol, and 3% of isoprene glycol.

9. The method for preparing the soothing, repairing and moisturizing facial cream according to any one of claims 3 to 8, characterized in that: The following steps are involved: (1) Heat water to 80-85° C., add glycerin, thickener, sodium hyaluronate, and dipotassium glycyrrhizinate, and homogenize and disperse evenly to form an aqueous phase; (2) petrolatum, caprylic / capric triglyceride, isononyl isononanoate, Lipomulse TM Luxe MB, 1000, RFA C1618, cholesterol, ceramide NP, glyceryl stearate SE, meadowfoam seed oil, opuntia cactus fruit extract, phytosphingosine, ceramide AP, and tetraacetyl phytosphingosine were mixed evenly, heated to 80-85°C, and stirred until the raw materials were completely dissolved to form an oil phase; (3) Slowly pour the oil phase into the water phase while turning on the homogenizer until the emulsification is uniform; (4) Cool down to 40-45° C., add preservatives and bisabolol in sequence, and stir evenly to obtain a soothing, repairing and moisturizing facial cream.

10. Use of the soothing, repairing and moisturizing facial cream according to any one of claims 1 to 8 in the preparation of soothing, repairing and moisturizing products.

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