Granulation method and granulation equipment for veterinary drug granules
By using spray coating technology to overmold the granules during the granules of veterinary medicine, the problem of low dissolution and bioavailability of drug ingredients in traditional methods is solved, and the delayed release of drug efficacy and stability is achieved.
Patent Information
- Application Number
- CN202510132848.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-06
- Publication Date
- 2025-04-11
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The traditional veterinary drug granules granulation method has problems with low dissolution and bioavailability of drug components, and the composition of complex materials leads to poor compaction and molding, resulting in the inability to effectively exert the efficacy of the drug.
The spray coating technology is used to overmold the granule during the granule granulation process, and the release of the drug effect is delayed through multi-direction and two-stage spraying operations, and the effect of spray solidification and coating is ensured through temperature and humidity regulation.
It improves the dissolution and bioavailability of drug ingredients, delays the release of drug effects, ensures that the drug can effectively reach the stomach of livestock, exerts the original drug effects, and improves the stability and production efficiency of granules.
Smart Images

Figure CN119793327A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of veterinary drug processing, and in particular to a granulation method and granulation equipment for veterinary drug granules. Background Art
[0002] In the traditional production process of Chinese veterinary medicine, the preparation of granules has always been a technical problem. Traditional granulation methods often have the following significant disadvantages, which limit the quality and efficacy of Chinese veterinary granules: First, the pretreatment process of raw materials in traditional granulation methods is relatively rough, often just simple crushing and mixing, which leads to low dissolution and bioavailability of drug components. Due to the complexity and diversity of Chinese herbal medicines themselves, simple processing cannot fully release the active ingredients in the medicinal materials, thus affecting the efficacy of the drugs.
[0003] The prior art provides a granulation method for Chinese veterinary granules, application number CN202411139673.5. The application adopts ultrafine grinding technology to grind Chinese herbal medicine raw materials to nanometer or micrometer level. This innovative method greatly improves the solubility and bioavailability of drug components. The traditional Chinese herbal medicine grinding method often has large particles, which makes it difficult to fully release the drug components and affects the efficacy. The ultrafine grinding technology makes the drug components easier to dissolve through fine grinding, thereby enhancing the efficacy. This has significant advantages for the absorption and utilization of the animal body and helps to achieve rapid and efficient treatment purposes. However, the application still has the following problems:
[0004] With the development of animal husbandry, the material composition of veterinary granules has become increasingly complex, resulting in a large number of granule ingredients. Therefore, the traditional compression molding granulation method alone cannot achieve a good compaction molding effect. The uncompacted granules will be crushed and mixed into the drug, which will lead to the premature release of the ingredients, making it impossible for the drug to effectively reach the stomach of the livestock and thus fail to achieve the original efficacy. Summary of the invention
[0005] The purpose of the present invention is to provide a technical solution, which performs a spray coating operation during the granulation process of the granules, and can delay the release of the drug effect while coating the granules, so as to solve the problems in the prior art mentioned in the above background technology.
[0006] To achieve the above object, the present invention adopts the following technical solutions:
[0007] A method for preparing veterinary drug granules comprises the following steps:
[0008] Material crushing: the component materials of the veterinary drug granules enter the crusher through the feed port for crushing, and the crushed materials enter the mixer through the discharge port of the crusher;
[0009] Material mixing: in the mixer, the crushed materials are evenly mixed, and the mixed materials enter the first shell of the granulating mechanism through the feeding port;
[0010] Compression granulation, the mixed material is pressed by the pressing roller inside the first shell, and pressed into granular granules through the forming orifice plate;
[0011] Spray coating, the compressed granules fall into the second shell, the first spray head and the second spray head spray coat the granules, and the spray solidifies on the surface of the granules to form a coating;
[0012] Temperature and humidity control: the temperature and humidity sensor detects the temperature and humidity inside the second shell in real time, and the PLC controller adjusts the spray speed and the rotation speed of the rotating rod according to the detection data to ensure the effective coagulation and coating of the spray on the surface of the granules;
[0013] The particles are turned over and discharged. The rotating plate rotates inside the second shell to push the granules to turn over, so that the spray covers the surface of the granules more evenly, and the granules are discharged from the discharge port at the same time.
[0014] The present invention also provides a granulation device for veterinary drug granules, which adopts the granulation method for veterinary drug granules, including a mixer, a pulverizer and a granulation mechanism, wherein the component materials of the granules are pulverized by the pulverizer, then introduced into the pulverizer for mixing, and then introduced into the granulation mechanism for compression and granulation operation;
[0015] The granulating mechanism comprises a first shell and a second shell, the first shell is installed above the second shell and a forming orifice plate is installed between the two, a pressing roller is rotatably installed inside the first shell, and the pressing roller is cooperatively installed on the upper surface of the forming orifice plate;
[0016] The interior of the second shell is rotatably installed with a first rotating rod and a second rotating rod through a rotating tube axis, and a first spray head is installed on the first rotating rod and the second rotating rod. The first spray head sprays and coats the granules formed and falling from the bottom of the forming hole plate, and the granules coated by the spray form a coating after the spray on the outer surface solidifies.
[0017] Preferably, a first spray chamber and a second spray chamber are provided inside the second shell, and when the granules are located inside the first spray chamber, they are sprayed through the first spray head and the second spray head, and when the granules are located inside the second spray chamber, they are sprayed through the first spray head on the second rotating rod.
[0018] Preferably, a first spray head is installed on the lower surface of the first rotating rod, and first spray heads are installed on the upper and lower surfaces of the second rotating rod. The first spray head on the lower surface of the first rotating rod and the first spray head on the upper surface of the second rotating rod perform the first stage of spraying, and the first spray head on the lower surface of the second rotating rod performs the second stage of spraying.
[0019] Preferably, a second spray head is installed on the inner side surface of the second shell through a nozzle seat, and the part of the rotating tube shaft located inside the second shell is also installed with a nozzle seat through the nozzle seat, and the nozzle seat can spray and cover the side of the granules; specifically, a temperature and humidity sensor is also arranged inside the second shell.
[0020] Preferably, a rotating plate is rotatably installed inside the second shell through a rotating tube axis, and a discharge port is provided on the side of the second shell. Under the rotation of the rotating plate, the granules are flipped inside the second shell and discharged from the discharge port at the same time; under the flipping of the rotating plate, the first spray head can better perform a comprehensive spray operation on the granules inside the second shell.
[0021] Preferably, the first shell is provided with a rotating shaft seat for rotatably mounting the roller shaft of the pressing roller, and a plurality of forming holes are evenly distributed on the forming hole. The material inside the first shell is pressed by the pressing roller and passes through the forming holes to be pressed into granular granules.
[0022] Preferably, the first rotating rod is mounted on the rotating tube shaft and is attached to the lower surface of the forming orifice plate. During the rotation of the first rotating rod, the granules pressed to the bottom of the forming orifice plate are periodically sheared.
[0023] Preferably, a rotating shaft seat is installed at the bottom of the second shell, and the rotating tube shaft is rotatably installed inside the rotating shaft seat. A second driver for driving the rotating tube shaft to rotate is arranged on one side of the rotating shaft seat. The rotating tube shaft is arranged as a hollow tube shaft, and a liquid delivery hole is arranged at the bottom of the rotating tube shaft. A feeding barrel is arranged on the rotating sleeve of the rotating tube shaft located outside the liquid delivery hole, and sealed bearings are arranged between both ends of the feeding barrel and the rotating tube shaft, so that the rotating tube shaft can rotate in a sealed manner in the feeding barrel. At the same time, a liquid delivery pipe is connected to one side of the feeding barrel, and the liquid delivery pipe can deliver spray liquid to the inside of the rotating tube shaft through the liquid delivery hole.
[0024] Preferably, the mixer and the pulverizer are mounted on a frame, and the pulverizer is provided with a feed port for feeding a variety of material components. After being pulverized by the pulverizer, the material enters the mixer for mixing, and then passes into the granulation mechanism for granulation and molding operations; a first driver and a second driver are installed on the frame, and the first driver drives the mixer and the pulverizer at the same time through a transmission belt, while the second driver is used to drive the granulation mechanism and the internal structure of the granulation mechanism.
[0025] Technical effects and advantages of the present invention: Compared with the prior art, the granulation method and granulation equipment of veterinary drug granules proposed by the present invention have the following advantages:
[0026] The present invention uses a granulating mechanism to perform spray coating operation during the granulation process of the granules, and can delay the release of the drug effect while coating the granules. The multi-directional and two-stage spraying can obtain a comprehensive spray coating effect, and simultaneously obtain a continuous granulation, coating and discharging process. BRIEF DESCRIPTION OF THE DRAWINGS
[0027] Figure 1 This is one of the structural schematic diagrams of the granulation equipment in the embodiment of the present invention;
[0028] Figure 2 This is the second structural schematic diagram of the granulation equipment in the embodiment of the present invention;
[0029] Figure 3 This is the third structural schematic diagram of the granulation equipment in the embodiment of the present invention;
[0030] Figure 4 It is a partial structural schematic diagram of a granulation device in an embodiment of the present invention;
[0031] Figure 5 It is a schematic diagram of the top view of the granulation mechanism in an embodiment of the present invention;
[0032] Figure 6 It is a side structural schematic diagram of a granulation mechanism in an embodiment of the present invention;
[0033] Figure 7 For the present invention Figure 6 A schematic diagram of the enlarged structure at A in the middle;
[0034] Figure 8 For the present invention Figure 7 A schematic diagram of the enlarged structure at B in the middle;
[0035] Fig. 9 Schematic diagram of two sets of rotating rods and a spray head in an embodiment of the present invention.
[0036] In the figure:
[0037] 11. Frame; 12. Mixer; 13. Crusher; 14. First drive; 15. Second drive; 16. Drive belt; 17. Feeding port;
[0038] 2. Granulating mechanism; 21. First shell; 22. Second shell; 23. Discharge port; 24. Rotating shaft seat; 25. Forming orifice plate; 26. Pressing roller; 27. Rotating tube shaft; 28. Feeding barrel; 29. Liquid feeding pipe; 210. First rotating rod; 211. Second rotating rod; 212. First spray head; 213. Second spray head; 214. Nozzle seat; 215. Temperature and humidity sensor; 216. Rotating plate; 217. PLC controller; 218. First spray chamber; 219. Second spray chamber; 220. Liquid feeding hole. DETAILED DESCRIPTION
[0039] The subject matter described herein will now be discussed with reference to example implementations. It should be understood that the discussion of these implementations is only to enable those skilled in the art to better understand and implement the subject matter described herein, and the functions and arrangements of the elements discussed may be changed without departing from the scope of protection of the contents of this specification. Various examples may omit, replace, or add various processes or components as needed. In addition, the features described in some examples may also be combined in other examples.
[0040] The invention provides Figures 1 to 9 As shown, the present invention provides a method for granulating veterinary drug granules, comprising the following steps:
[0041] Material crushing: the component materials of the veterinary drug granules enter the crusher 13 through the feed port for crushing, and the crushed materials enter the mixer 12 through the discharge port 23 of the crusher 13;
[0042] Material mixing: In the mixer 12, the crushed materials are uniformly mixed, and the mixed materials enter the first housing 21 of the granulating mechanism 2 through the feeding port 17;
[0043] Pressing and granulating: the mixed material is pressed by the pressing roller 26 inside the first housing 21 and pressed into granular granules through the forming orifice plate 25;
[0044] Spray coating: the compressed granules fall into the second housing 22, and the first spray head 212 and the second spray head 213 spray coat the granules, and the spray solidifies on the surface of the granules to form a coating;
[0045] Temperature and humidity control: the temperature and humidity sensor 215 detects the temperature and humidity inside the second housing 22 in real time, and the PLC controller 217 adjusts the spray speed and the rotation speed of the rotating rod according to the detection data to ensure the effective coagulation and coating of the spray on the surface of the granules;
[0046] The granules are turned over and discharged. The rotating plate 216 rotates inside the second shell 22 to push the granules to turn over, so that the spray can cover the surface of the granules more evenly, and the granules are discharged from the discharge port 23 at the same time.
[0047] The present invention also provides a granulation device for veterinary drug granules. Figures 1 to 9 As shown, a granulation device for veterinary drug granules includes a mixer 12, a grinder 13 and a granulation mechanism 2. The component materials of the granules are crushed by the grinder 13, then introduced into the grinder 13 for mixing and then introduced into the granulation mechanism 2 for compression and granulation operation;
[0048] The granulating mechanism 2 comprises a first housing 21 and a second housing 22. The first housing 21 is mounted above the second housing 22 and a forming orifice plate 25 is mounted between the first housing 21 and a pressing roller 26 is rotatably mounted inside the first housing 21. The pressing roller 26 is mounted on the upper surface of the forming orifice plate 25.
[0049] The interior of the second shell 22 is rotatably mounted with a first rotating rod 210 and a second rotating rod 211 via a rotating tube shaft 27, and a first spray head 212 is mounted on the first rotating rod 210 and the second rotating rod 211. The first spray head 212 sprays and coats the granules formed and falling from the bottom of the forming hole plate 25, and the spray-coated granules form a coating after the spray on the outer surface solidifies.
[0050] Working principle: material crushing and mixing, the component materials of the veterinary drug granules enter the pulverizer 13 through the feed port for crushing, and the crushed materials enter the mixer 12 through the discharge port 23 of the pulverizer 13; in the mixer 12, the crushed materials are evenly mixed, and the mixed materials enter the first shell 21 of the granulation mechanism through the feed port 17; the mixed materials are pressed by the pressing roller 26 inside the first shell 21, and pressed into granular granules through the forming orifice plate 25. The rotation of the pressing roller 26 ensures that the materials pass through the forming orifice plate 25 evenly to form granular granules; spray coating, spray coating, the pressed granules fall into the second shell 22, and the first spray head 212 and the second spray head 213 spray coat the granules. The spray solidifies on the surface of the granules to form a coating, thereby achieving coating and molding of the granules; multi-directional spraying, a plurality of spray heads are installed on the first rotating rod 210 and the second rotating rod 211, respectively, to perform the first stage and the second stage of spray coating on the granules, thereby ensuring the comprehensiveness and uniformity of the spray coverage; temperature and humidity control, the temperature and humidity sensor 215 detects the temperature and humidity inside the second shell 22 in real time, and the PLC controller 217 adjusts the spray speed and the rotation speed of the rotating rod according to the detection data, thereby ensuring the effective coagulation and coating of the spray on the surface of the granules; dynamic adjustment, the PLC controller 217 monitors and adjusts the spray speed, the rotation speed of the rotating rod and the discharging speed of the granules in real time through the data of the temperature and humidity sensor 215, thereby ensuring the stability of the granulation process and the quality of the granules; granule turning and discharging, the granules turn over, and the rotating plate 216 rotates inside the second shell 22 to push the granules to turn over, so that the spray covers the surface of the granules more evenly; discharging, the granules are discharged from the discharging port 23 under the push of the rotating plate 216, thereby completing the entire granulation process;
[0051] like Figure 6As shown, the interior of the second shell 22 is provided with a first spray chamber 218 and a second spray chamber 219. When the granules are located in the first spray chamber 218, they are sprayed through the first spray head 212 and the second spray head 213. When the granules are located in the second spray chamber 219, they are sprayed through the first spray head 212 on the second rotating rod 211. Since the spray coverage of the spray head is limited, when the granules are located in the second spray chamber 219, only the first spray head 212 on the second rotating rod 211 can be effectively operated.
[0052] like Figures 6 to 8 As shown, a first spray head 212 is installed on the lower surface of the first rotating rod 210, and first spray heads 212 are installed on the upper and lower surfaces of the second rotating rod 211. The first spray head 212 on the lower surface of the first rotating rod 210 and the first spray head 212 on the upper surface of the second rotating rod 211 perform the first stage of spraying, and the first spray head 212 on the lower surface of the second rotating rod 211 performs the second stage of spraying.
[0053] like Figure 6 and Figure 7 As shown, the inner side surface of the second shell 22 is equipped with a second spray head 213 through a nozzle seat 214, and the portion of the rotating tube shaft 27 located inside the second shell 22 is also equipped with a nozzle seat 214 through the nozzle seat 214, and the nozzle seat 214 can spray and cover the side of the granules; specifically, the interior of the second shell 22 is also provided with a temperature and humidity sensor 215, and the temperature and humidity sensor 215 is used to detect the temperature and humidity inside the second shell 22, because the temperature and humidity inside the second shell 22 are related to the effect of the spray on the coagulation and coating of the granules surface, the temperature and humidity inside the second shell 22 are closely related to the spray speed and other data of the first spray head 212 and the second spray head 213.
[0054] like Figure 6 and Figure 8 As shown, a rotating plate 216 is rotatably installed inside the second shell 22 through a rotating tube shaft 27, and a discharge port 23 is provided on the side of the second shell 22. Under the rotation of the rotating plate 216, the granules are turned over inside the second shell 22 and discharged from the discharge port 23; under the turning of the rotating plate 216, the first spray head 212 can better perform a comprehensive spray operation on the granules inside the second shell 22.
[0055] In order to achieve effective coagulation and coating of the spray coating on the surface of the granules, that is, to realize the dynamic association of data such as temperature and humidity with spray speed, a PLC controller 217 and a temperature controller are also included. The temperature controller is used to control the structure inside the second shell 22. The PLC controller 217 uses the data collected by the temperature and humidity sensor 215 to dynamically adjust the spray speed and the rotation speed of the first rotating rod 210 and the second rotating rod 211 in real time.
[0056] like Figure 5 and Figure 6 As shown, specifically, the first shell 21 is provided with a rotating shaft seat 24 for rotatably mounting the roller shaft of the pressing roller 26, and a plurality of forming holes are evenly distributed on the forming hole plate 25. The material inside the first shell 21 is pressed by the pressing roller 26 and passes through the forming holes to be pressed into granular granules.
[0057] like Figure 7 As shown, the first rotating rod 210 is installed on the rotating tube shaft 27 and is attached to the lower surface of the forming hole plate 25. During the rotation of the first rotating rod 210, the granules pressed to the bottom of the forming hole plate 25 will be sheared, thereby ensuring the uniformity of the pressed extrusion length of the granules.
[0058] like Figure 6 As shown, a rotating shaft seat 24 is installed at the bottom of the second shell 22, and the rotating tube shaft 27 is rotatably installed inside the rotating shaft seat 24. A second driver 15 for driving the rotating tube shaft 27 to rotate is arranged on one side of the rotating shaft seat 24. Specifically, the second driver 15 and the rotating tube shaft 27 can be driven by bevel gears; the rotating tube shaft 27 is set as a hollow tube shaft, and a liquid delivery hole 220 is set at the bottom of the rotating tube shaft 27. A feeding barrel 28 is provided on the rotating sleeve of the rotating tube shaft 27 located outside the liquid delivery hole 220. Sealed bearings are arranged between both ends of the feeding barrel 28 and the rotating tube shaft 27, so that the rotating tube shaft 27 can be sealed and rotated in the feeding barrel 28. At the same time, a liquid delivery pipe 29 is connected to one side of the feeding barrel 28, and the liquid delivery pipe 29 can deliver spray liquid to the inside of the rotating tube shaft 27 through the liquid delivery hole 220. Specifically, an infusion pump is disposed inside the liquid delivery tube 29, and the first rotating rod 210 and the second rotating rod 211 are both configured as hollow structures, so that the liquid can be directly delivered to the first spray head 212 and the second spray head 213 through the rotating rods. Figure 6 As shown, the second spray head 213 located on the inner wall of the second shell 22 can directly set a pipeline on the outer wall of the second shell 22 to transport the liquid.
[0059] like Figures 1 to 4As shown, the mixer 12 and the pulverizer 13 are installed on the frame 11, and the pulverizer 13 is provided with a feed port for feeding a variety of material components. The materials are crushed by the pulverizer 13 and then enter the mixer 12 for mixing, and then pass into the granulation mechanism 2 for granulation and molding operation; the frame 11 is installed with a first driver 14 and a second driver 15. The first driver 14 drives the mixer 12 and the pulverizer 13 at the same time through a transmission belt 16, and the second driver 15 is used to drive the granulation mechanism 2 and the internal structure of the granulation mechanism 2. Specifically, a feed port 17 is provided at the bottom of the mixer 12, and the component materials mixed in the mixer 12 are transported to the first housing 21 through the feed port 17.
[0060] In summary, the present invention also has the following comprehensive effects: material crushing and mixing, material crushing, the component materials of the veterinary drug granules enter the crusher 13 through the feed port for crushing, and the crushed materials enter the mixer 12 through the discharge port 23 of the crusher 13; material mixing, in the mixer 12, the crushed materials are evenly mixed, and the mixed materials enter the first shell 21 of the granulation mechanism through the feed port 17; pressing granulation, pressing granulation, the mixed materials are pressed by the pressing roller 26 inside the first shell 21, and pressed into granular granules through the forming orifice plate 25. The rotation of the pressing roller 26 ensures that the materials pass through the forming orifice plate 25 evenly to form granular granules; spray coating, spray coating, the pressed granules fall into the second shell 22, and the first spray head 212 and the second spray head 213 spray coat the granules. The spray solidifies on the surface of the granules to form a coating, thereby achieving coating molding of the granules; multi-directional spraying, a plurality of spray heads are installed on the first rotating rod 210 and the second rotating rod 211, respectively, to perform the first stage and the second stage of spray coating on the granules, thereby ensuring the comprehensiveness and uniformity of the spray coverage; temperature and humidity control, temperature and humidity detection, the temperature and humidity sensor 215 detects the temperature and humidity inside the second shell 22 in real time, and the PLC controller 217 adjusts the spray speed and the rotation speed of the rotating rod according to the detection data, thereby ensuring the effective coagulation and coating of the spray on the surface of the granules; dynamic adjustment, the PLC controller 217 monitors and adjusts the spray speed, the rotation speed of the rotating rod and the discharging speed of the granules in real time through the data of the temperature and humidity sensor 215, thereby ensuring the stability of the granulation process and the quality of the granules; granule turning and discharging, the granules turn over, the rotating plate 216 rotates inside the second shell 22, driving the granules to turn over, so that the spray covers the surface of the granules more evenly; discharging, the granules are discharged from the discharging port 23 under the push of the rotating plate 216, thereby completing the entire granulation process;
[0061] Improve the compaction and molding effect. Through the cooperation of the pressing roller 26 and the molding hole plate 25, ensure that the material passes through the molding hole plate 25 evenly during the compression and granulation process to form granular granules, thereby improving the compaction and molding effect; delay the release of drug efficacy. The spray coating operation forms a coating on the surface of the granules to delay the release of drug efficacy and ensure that the drug can effectively reach the stomach of the livestock and exert its original efficacy; multi-directional spray coating, multi-directional and two-stage spray coating ensures comprehensive coverage of the granule surface, improves the spray coating effect, and enhances the stability and efficacy of the granules; real-time monitoring and adjustment, temperature and humidity sensor 215 and PLC controller 21 7, to achieve real-time monitoring and dynamic adjustment of the granulation process, to ensure the effective coagulation and coating of the spray on the surface of the granules, to improve the stability of the granulation process and the quality of the granules; continuous granulation and discharging, through the turning of the rotating plate 216, to achieve continuous turning and discharging of the granules, to ensure the continuity and efficiency of the granulation process, to improve production efficiency; to improve production efficiency and quality, through the above technical scheme, the granulation method and equipment of the present invention can effectively solve the problem of poor compaction molding effect caused by complex granule ingredients in the prior art, to improve production efficiency and granule quality, to ensure the efficacy and stability of the drug.
[0062] The above describes an embodiment of the present invention, but this embodiment is not limited to the above specific implementation methods. The above specific implementation methods are merely illustrative and not restrictive. Under the guidance of this embodiment, ordinary technicians in this field can also make many forms, all of which are protected by this embodiment.
Claims
1. A method for preparing veterinary drug granules, characterized in that: The steps include: Material crushing: the component materials of the veterinary drug granules enter the crusher (13) through the feed inlet for crushing, and the crushed materials enter the mixer (12) through the discharge port (23) of the crusher (13); Material mixing: in the mixer (12), the crushed materials are uniformly mixed, and the mixed materials enter the first housing (21) of the granulating mechanism (2) through the feeding port (17); Pressing and granulating, the mixed material is pressed by a pressing roller (26) inside the first shell (21), and pressed into granular granules through a forming orifice plate (25); Spray coating, the compressed granules fall into the interior of the second shell (22), the first spray head (212) and the second spray head (213) spray coat the granules, and the spray solidifies on the surface of the granules to form a coating; Temperature and humidity control: the temperature and humidity sensor (215) detects the temperature and humidity inside the second housing (22) in real time, and the PLC controller (217) adjusts the spray speed and the rotation speed of the rotating rod according to the detection data to ensure that the spray is effectively solidified and coated on the surface of the granules; The particles are turned over and discharged. The rotating plate (216) rotates inside the second shell (22) to push the granules to turn over, so that the spray can cover the surface of the granules more evenly, and the granules are discharged from the discharge port (23).
2. A granulation device for veterinary drug granules, using the granulation method for veterinary drug granules, characterized in that: It comprises a mixer (12), a pulverizer (13) and a granulating mechanism (2). The component materials of the granules are pulverized by the pulverizer (13), then introduced into the pulverizer (13) for mixing, and then introduced into the granulating mechanism (2) for compression and granulation. The granulating mechanism (2) comprises a first shell (21) and a second shell (22), the first shell (21) being mounted above the second shell (22) and a forming orifice plate (25) being mounted between the first shell (21) and a pressing roller (26) being rotatably mounted inside the first shell (21), and the pressing roller (26) being mounted in cooperation with the upper surface of the forming orifice plate (25); A first rotating rod (210) and a second rotating rod (211) are rotatably mounted inside the second housing (22) via a rotating tube shaft (27); a first spray head (212) is mounted on the first rotating rod (210) and the second rotating rod (211); the first spray head (212) sprays and coats the granules formed and falling from the bottom of the forming hole plate (25); the granules that are spray-coated form a coating after the spray on the outer surface solidifies.
3. A granulation device for veterinary drug granules according to claim 2, characterized in that: A first spray chamber (218) and a second spray chamber (219) are arranged inside the second housing (22); when the granules are located inside the first spray chamber (218), they are sprayed through the first spray head (212) and the second spray head (213); and when the granules are located inside the second spray chamber (219), they are sprayed through the first spray head (212) on the second rotating rod (211).
4. A granulation device for veterinary drug granules according to claim 3, characterized in that: The first rotating rod (210) is provided with a first spray head (212) on its lower surface, and the first spray head (212) is provided on both its upper and lower surfaces. The first spray head (212) on the lower surface of the first rotating rod (210) and the first spray head (212) on the upper surface of the second rotating rod (211) perform spraying in the first stage, and the first spray head (212) on the lower surface of the second rotating rod (211) performs spraying in the second stage.
5. A granulation device for veterinary drug granules according to claim 4, characterized in that: The inner side surface of the second shell (22) is mounted with a second spray head (213) via a nozzle seat (214); the portion of the rotating tube shaft (27) located inside the second shell (22) is also mounted with a nozzle seat (214) via the nozzle seat (214); the nozzle seat (214) can spray and cover the side surfaces of the granules; specifically, a temperature and humidity sensor (215) is also disposed inside the second shell (22).
6. A granulation device for veterinary drug granules according to claim 5, characterized in that: A rotating plate (216) is rotatably mounted inside the second shell (22) via a rotating tube shaft (27); a discharge port (23) is provided on the side of the second shell (22); and when the rotating plate (216) is rotated, the granules are turned over inside the second shell (22) and discharged from the discharge port (23); when the rotating plate (216) is turned over, the first spray head (212) can better perform a comprehensive spray operation on the granules inside the second shell (22).
7. A granulation device for veterinary drug granules according to claim 6, characterized in that: The first shell (21) is provided with a rotating shaft seat (24) for rotatably mounting the roller shaft of the pressing roller (26), and a plurality of forming holes are evenly distributed on the forming hole plate (25). The material inside the first shell (21) is pressed by the pressing roller (26) and passes through the forming holes to be pressed into granular granules.
8. A granulation device for veterinary drug granules according to claim 7, characterized in that: The first rotating rod (210) is mounted on the rotating tube shaft (27) and is attached to the lower surface of the forming hole plate (25). During the rotation of the first rotating rod (210), the granules pressed to the bottom of the forming hole plate (25) are periodically sheared.
9. A granulation device for veterinary drug granules according to any one of claims 2 to 8, characterized in that: A rotating shaft seat (24) is installed at the bottom of the second shell (22), and the rotating shaft (27) is rotatably installed inside the rotating shaft seat (24). A second driver (15) for driving the rotating shaft (27) to rotate is arranged on one side of the rotating shaft seat (24). The rotating shaft (27) is arranged as a hollow shaft, and a liquid delivery hole (220) is arranged at the bottom of the rotating shaft (27). A feeding cylinder (28) is arranged on the rotating sleeve of the rotating shaft (27) outside the liquid delivery hole (220). Sealed bearings are arranged between the two ends of the feeding cylinder (28) and the rotating shaft (27), so that the rotating shaft (27) can rotate in a sealed manner in the feeding cylinder (28). At the same time, a liquid delivery pipe (29) is connected to one side of the feeding cylinder (28), and the liquid delivery pipe (29) can deliver spray liquid to the inside of the rotating shaft (27) through the liquid delivery hole (220).
10. A granulation device for veterinary drug granules according to claim 2, characterized in that: The mixer (12) and the pulverizer (13) are mounted on a frame (11); the pulverizer (13) is provided with a feed port for feeding a plurality of material components; the materials are pulverized by the pulverizer (13) and then enter the mixer (12) for mixing, and then enter the granulating mechanism (2) for granulation and molding; a first driver (14) and a second driver (15) are mounted on the frame (11); the first driver (14) drives the mixer (12) and the pulverizer (13) at the same time through a transmission belt (16), and the second driver (15) is used to drive the granulating mechanism (2) and the internal structure of the granulating mechanism (2).
Citation Information
Patent Citations
Granulation method of traditional Chinese veterinary medicine granules
CN118662474A