Device for positioning in-vivo cavity tissue

Abstract

The invention relates to the technical field of medical instruments, and provides a device for positioning in-vivo cavity tissue, the device comprises a catheter assembly, a balloon body and a light-emitting assembly, the catheter assembly is provided with a catheter cavity, the near end of the catheter assembly is provided with a first through hole, and the balloon body is arranged at the near end of the catheter assembly; the light-emitting assembly comprises a controller and an optical fiber, the input end of the optical fiber is connected with the controller, the output end of the optical fiber penetrates into the catheter cavity, the input end of the optical fiber is provided with a light emitting section on the side, away from the near end of the catheter assembly, of the balloon body, and the light emitting section extends in the length direction of the catheter assembly; light emitted by the controller is transmitted to the light emitting section through the input end of the optical fiber and is emitted through the guide pipe assembly. After the balloon body is expanded, the catheter assembly and the balloon body integrally move, positioning in an operation area is achieved, the light emitting section is aligned with the operation area, and the operation area is conveniently identified; wherein the outer diameter of the optical fiber is small, and the cross sectional area of the catheter assembly is small, so that the catheter assembly can smoothly pass through the human body.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a device for locating body cavity tissue. Background Art

[0002] Combination Figure 1 , the prostate 2 surrounds a portion of the urethra 3. The prostate 2 continues to enlarge throughout a person's life. In some men, an enlarged prostate can cause the inner area of ​​the prostate 2 to press against the urethra 3, increasing the resistance of urine in the bladder 1 to flow through the area of ​​the urethra 3 surrounded by the prostate 2. As a result, the bladder 1 must exert more pressure to force urine through the increased urethral resistance, causing the muscle wall of the bladder 1 to remodel and become stiffer. This increased urethral resistance and increased urine stream stiffness, along with bladder wall hypertrophy, can lead to a variety of lower urinary tract symptoms (LUTS) that can significantly reduce a person's quality of life. These symptoms include a weak or intermittent urine stream during urination, straining during urination, hesitation before starting to urinate, a feeling that the bladder 1 is not completely empty even after urinating, dribbling or leaking urine at the end of urination, increased frequency of urination, especially at night, and urgency to urinate.

[0003] Existing prostate surgery reduces urethral resistance by removing the diseased and hyperplastic part of the prostate. However, due to the close anatomical relationship between the prostate and the urethra, the urethra wrapped by the prostate is difficult to identify, which makes it easy to cut the urethra when removing the diseased prostate, resulting in the inability to urinate autonomously during the 3 to 5 days recovery period after surgery. Patients have to use a catheter to assist urination. Summary of the invention

[0004] The purpose of the present invention is to provide a device for locating body cavity tissue, aiming to solve the technical problem that it is difficult to mark the surgical area during the existing surgery.

[0005] The present application provides a device for locating body cavity tissue, the device for locating body cavity tissue comprising: A catheter assembly, wherein the catheter assembly has a lumen, and a proximal end of the catheter assembly has a first through hole, wherein the first through hole is in communication with the lumen; A balloon body, which is disposed at the proximal end of the catheter assembly and is communicated with the first through hole; A light-emitting component, the light-emitting component includes a controller and an optical fiber, the input end of the optical fiber is connected to the controller, the output end of the optical fiber is arranged in the lumen, the output end of the optical fiber is located on the side of the proximal end of the balloon body away from the catheter assembly, and a light-emitting section is provided, and the light-emitting section extends along the length direction of the catheter assembly; the light emitted by the controller is transmitted to the light-emitting section through the input end of the optical fiber, and is emitted through the catheter assembly.

[0006] In one embodiment, the outer diameter of the light-emitting section gradually decreases in a direction away from the input end of the optical fiber.

[0007] In one embodiment, the lumen includes a balloon channel, an optical path channel and a drainage channel that are independent of each other, the proximal end of the balloon channel is connected to the first through hole, the optical fiber is arranged in the optical path channel, and the drainage channel is used to allow liquid to flow from the proximal end of the catheter assembly to the distal end of the catheter assembly.

[0008] In one of the embodiments, in the cross section of the catheter assembly, the optical path channel is located in the middle of the tube cavity, and the light emitting section is linearly extended along the length direction of the optical path channel.

[0009] In one of the embodiments, in the cross section of the catheter assembly, the optical path channel is annularly arranged around the circumference of the tube cavity, and the light emitting section is spirally arranged in the optical path channel.

[0010] In one embodiment, the catheter assembly includes a first light transparent tube, a third light transparent tube, and a second light transparent tube which are nested in sequence from the outside to the inside, the balloon channel is formed between the first light transparent tube and the third light transparent tube, the drainage channel is formed between the third light transparent tube and the second light transparent tube, and the interior of the second light transparent tube forms the light path channel.

[0011] In one embodiment, the catheter assembly is integrally injection molded with the optical fiber.

[0012] In one embodiment, the controller controls the light emitting section to emit laser.

[0013] In one of the embodiments, the input end of the optical fiber extends out of the catheter assembly and is provided with a first connector, and the controller is provided with a second connector detachably connected to the first connector.

[0014] In one embodiment, the controller includes a shell, a light source generator and a control board. The shell is located outside the first light-transmitting tube, and the control board and the light source generator are installed inside the shell. The light source generator is connected to the input end of the optical fiber, and the control board is used to control the light source generator to generate light.

[0015] In one of the embodiments, the controller further includes a power adjustment component, which is electrically connected to the control board and is used to adjust the optical power of the light source generator.

[0016] In one embodiment, the light source generator includes lamp beads of multiple colors, and the controller also includes a color adjustment component, which is electrically connected to the control board and is used to switch the multiple lamp beads so that the light source generator generates light of different colors.

[0017] In one embodiment, the device for locating intracavitary tissue also includes a metal sensor, which includes a metal sensing coil and a signal converter. The signal converter is integrated in the controller, and the metal sensing coil is located on the side of the light emitting section away from the balloon. The metal sensing coil is electrically connected to the signal converter via a wire.

[0018] In one embodiment, the device for locating intracavitary tissue in the body also includes a spectral measurement unit. The light emitted by the light emitting segment is reflected by an obstruction to form a return light. The light emitting segment receives the return light and transmits the return light to the spectral measurement unit. The spectral measurement unit is used to analyze the phase delay and intensity attenuation of the return light.

[0019] In one of the embodiments, the length of the light emitting section is 30 mm to 50 mm.

[0020] The beneficial effects of the device for locating intracorporeal tissue provided by the present invention are as follows: the proximal end of the catheter assembly enters the human body through the body cavity or channel of the human body, the fluid enters the balloon body through the lumen and the first through hole in turn, so that the balloon body expands, pulling the catheter assembly and the balloon body to move as a whole, and the expanded balloon body is positioned and clamped in the body cavity or channel of the human body to achieve positioning in the surgical area, the light emitting section is aligned with the surgical area, the light emitted by the controller is transmitted to the light emitting section through the input end of the optical fiber, and is emitted through the catheter assembly to mark the position of the body cavity or channel of the surgical area, solving the technical problem of difficulty in marking the surgical area during existing surgery, thereby locating the surgical cutting boundary in real time and reducing the risk of miscutting due to complex anatomical structure during surgery, and the controller is located outside the catheter assembly, the optical fiber is used to transmit light, and there is no need to generate light, and its outer diameter is small and occupies a small space, so that the cross-sectional area of ​​the catheter assembly is small, which is conducive to the smooth passage of the catheter assembly in the human body. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0022] Figure 1 A schematic diagram of the prostate and urethra of the human body; Figure 2 A schematic diagram of the structure of a device for locating body cavity tissue provided by an embodiment; Figure 3 A schematic diagram of the structure of the device for locating body cavity tissue after removing the catheter assembly and part of the shell; Figure 4 is a schematic diagram of the installation of an optical fiber in an embodiment; Figure 5 for Figure 2 Sectional view along line AA; Figure 6 A partial cross-sectional view of an optical fiber in a device for locating tissue in a body cavity; Figure 7 A schematic diagram of a first installation of a catheter assembly and an optical fiber; Figure 8 Schematic diagram of the second installation of the catheter assembly and the optical fiber.

[0023] Among them, the reference numerals in the figure are: 1. Bladder; 2. Prostate; 3. Urethra; 100, catheter assembly; 110, lumen; 111, balloon channel; 112, light path channel; 113, drainage channel; 114, partition wall; 115, first light-transmitting tube; 116, second light-transmitting tube; 117, third light-transmitting tube; 118, liquid-guiding port; 119, liquid-guiding channel; 1110, drug-delivery channel; 120, first through hole; 130, uniform light surface; 200, balloon body; 300, light emitting component; 310, controller; 311, housing; 312, light source generator; 313, control board; 314, power adjustment component; 315, color adjustment component; 320, optical fiber; 322, light emitting section; 410, metal sensing coil; 420, first connector; 430, second connector; 500. Spectral measurement unit. DETAILED DESCRIPTION

[0024] Embodiments of the present invention are described in detail below, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0025] Reference throughout the specification to "one embodiment" or "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment of the present application. Thus, when the phrases "in one embodiment" or "in some embodiments" appear in various places throughout the specification, not all references are to the same embodiment. Furthermore, in one or more embodiments, the particular features, structures, or characteristics may be combined in any suitable manner.

[0026] In the description of the present invention, it should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship are based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0027] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features.

[0028] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0029] Combination Figures 2 to 4 The device for locating the tissue of the body cavity provided by the present application includes a catheter assembly 100, a balloon body 200 and a light emitting assembly 300. The catheter assembly 100 has a lumen 110, and the proximal end of the catheter assembly 100 has a first through hole 120, and the first through hole 120 is connected to the lumen 110. The balloon body 200 is disposed at the proximal end of the catheter assembly 100, and the balloon body 200 is connected to the first through hole 120.

[0030] The light-emitting component 300 includes a controller 310 and an optical fiber 320. The controller 310 is located outside the catheter component 100. The input end of the optical fiber 320 is connected to the controller 310. The output end of the optical fiber 320 is located on the side of the balloon body 200 away from the proximal end of the catheter component 100 and is provided with a light-emitting section 322. The light-emitting section 322 extends along the length direction of the catheter component 100. The light emitted by the controller 310 is transmitted to the light-emitting section 322 through the input end of the optical fiber 320 and is emitted through the catheter component 100.

[0031] In this embodiment, the proximal end of the catheter assembly 100 enters the human body through the body cavity or channel of the human body, and the fluid enters the balloon body 200 through the lumen 110 and the first through hole 120 in turn, so that the balloon body 200 expands, pulling the catheter assembly 100 and the balloon body 200 to move as a whole, and the expanded balloon body 200 is positioned and clamped in the body cavity or channel of the human body to achieve positioning in the surgical area. The light emitting segment 322 is aligned with the surgical area, and the light emitted by the controller 310 is transmitted to the light emitting segment 322 through the input end of the optical fiber 320, and is emitted through the catheter assembly 100 to mark the position of the body cavity or channel of the surgical area, solving the technical problem that it is difficult to mark the surgical area during the existing surgery, thereby locating the surgical cutting boundary in real time and reducing the risk of miscutting due to complex anatomical structure during surgery. In addition, the controller 310 is located outside the catheter assembly 100, and the optical fiber 320 is used to transmit light without generating light. Its outer diameter is small and occupies a small space, so that the cross-sectional area of ​​the catheter assembly 100 is small, which is conducive to the smooth passage of the catheter assembly 100 in the human body.

[0032] The body cavity or passage of the human body may be a ureter, intestine, esophagus, lung passage, nasal cavity, blood vessel and oral cavity, etc. The surgical area may be a prostate, testicle, bladder, uterus, ovary, intestine, kidney, liver, pancreas, stomach, ear, nose, mouth, adipose tissue, muscle, brain, heart, lung, eye, skin, mucosal tissue, spinal cord, nerve tissue, cartilage, hard biological tissue, etc. The fluid used to expand the balloon body 200 may be gas or saline, etc., which is not limited here.

[0033] It should be noted that the distal end and proximal end in this application are defined relative to the operator. The end close to the operator is the proximal end, and the end far from the operator is the distal end.

[0034] In this embodiment, the optical fiber 320 is fixedly disposed in the lumen 110, which means that the optical fiber 320 is at least partially fixedly disposed in the lumen 110. The optical fiber 320 can be integrally formed with the catheter assembly 100 to achieve the fixed arrangement of the optical fiber 320, or it can be manufactured separately from the catheter assembly 100 and then fixedly installed in the catheter assembly 100 by means of gluing, welding, clamping, interference fit, etc.

[0035] In this embodiment, the balloon body 200 can be integrally formed with the catheter assembly 100, so as to realize seamless connection between the catheter assembly 100 and the balloon body 200, without interface stress concentration points, without assembly space and accommodating connection structures, and facilitating the design of a small cross-sectional area of ​​the balloon body 200. It is understood that in other embodiments, the balloon body 200 can be manufactured with the catheter assembly 100, and then the catheter assembly 100 can be sleeved by bonding, welding, clamping, interference fit, etc.

[0036] In this embodiment, see Figures 6 to 8 The cross section of the catheter assembly 100 and the cross section of the light-emitting section 322 can be circular, elliptical, polygonal or irregular independently of each other, and are not specifically limited here. The cross section refers to the cross section perpendicular to the length direction. The outer diameter of the catheter assembly 100 is the diameter of the circumscribed circle of its cross section. The outer diameter of the light-emitting section 322 refers to the diameter of the circumscribed circle of its cross section.

[0037] In this embodiment, the optical fiber 320 includes a core and a cladding, the refractive index of the core is higher than the refractive index of the cladding, and light is transmitted in the core by total internal reflection. The light output section 322 includes only the core, or the light output section 322 includes the core and the cladding, the thickness of the cladding is smaller than the thickness of the cladding at other positions, or the cladding of the light output section 322 has a partial gap, and light leaks from the core of the light output section 322, so that the light can be scattered, and the light output section 322 emits light, and the outer diameter of the light output section 322 is small, without increasing the outer diameter and cross-sectional area of ​​the catheter assembly 100. In some embodiments, in combination Figure 3 and Figure 6 , the outer diameter of the light-emitting section 322 gradually decreases in the direction away from the input end of the optical fiber 320. Due to light leakage in the light-emitting section 322, the luminous flux of the light-emitting section 322 gradually decreases, resulting in a possible decrease in brightness. The outer diameter of the light-emitting section 322 gradually decreases, increasing the contact surface between the light and the cladding / external medium, so that the proportion of leaked light in the light-emitting section 322 gradually increases, dynamically compensating the brightness, and achieving uniform brightness in the length direction of the light-emitting section 322, thereby avoiding misjudgment of the boundary of the surgical area during surgery.

[0038] Specifically, combined Figure 6 , the light-emitting section 322 adopts a processing and engraving process to achieve a gradual reduction in its outer diameter. For example, the surface of the light-emitting section 322 adopts a conical engraving process, so that the outer side surface of the light-emitting section 322 is a conical surface, and its outer diameter gradually and continuously decreases smoothly in the direction away from the input end of the optical fiber 320, so that the leakage light ratio of the light-emitting section 322 is continuously and smoothly increased, combined with the continuous and gradual reduction of the light flux, the brightness of the light-emitting section 322 along its length direction is comprehensively achieved.

[0039] In some embodiments, in combination Figure 2The periphery of the light emitting section 322 is provided with a uniform light surface 130 for uniformly dispersing the light, and / or the periphery of the catheter assembly 100 is provided with a uniform light surface 130 for uniformly dispersing the light, thereby achieving 360° circumferential uniform light emission, clearly locating the boundaries of the surgical area at various angles during the operation, improving the accuracy and safety of the operation, reducing the risk of miscutting due to complex anatomical structures or insufficient light, and eliminating the need to rotate the optical fiber 320 to adjust the light emission angle.

[0040] Optionally, the light homogenizing surface 130 is provided with 50-150 convex microstructures per millimeter.

[0041] Specifically, the light-homogenizing surface 130 is a frosted surface or a scattering particle coating to form more interfaces and have a better scattering effect on light.

[0042] Specifically, the light emitting section 322 and / or the outer periphery of the catheter assembly 100 are laser etched to form the light homogenizing surface 130. For example, a micron-scale concave-convex array is engraved on the outer periphery of the light emitting section 322 to destroy the total reflection condition and induce multi-angle scattering.

[0043] Specifically, a coating of titanium dioxide nanoparticles doped with resin is disposed on the periphery of the light-emitting section 322 and / or the catheter assembly 100. Titanium dioxide has a high refractive index and can effectively scatter light. The surface of the nano-titanium dioxide particles is highly active and interacts with the molecules in the resin matrix to form a strong chemical bond, thereby preventing the coating from falling off or peeling off during use.

[0044] Specifically, the light emitting section 322 and / or the periphery of the catheter assembly 100 are coated with quantum dot materials (such as CdSe / ZnS) to convert ordinary red light into a wavelength of 610nm~630nm, thereby enhancing the tissue penetration depth.

[0045] In some embodiments, the length of the light-emitting segment 322 is 30 mm to 50 mm, meeting the needs of different people including adults and children. For example, a 30 mm long light-emitting segment 322 is used for children to achieve short-range high-density scattering, matching the narrow cavity of children. A 50 mm long light-emitting segment 322 is used for adults to achieve long-range low-density scattering, covering larger lesion areas in adults, such as prostate hyperplasia with a volume of >80 mL.

[0046] In some embodiments, in combination Figure 4 , Figure 7 and Figure 8The lumen 110 includes a balloon channel 111, an optical path channel 112 and a drainage channel 113 which are independent of each other. The proximal end of the balloon channel 111 is connected to the first through hole 120, and the optical fiber 320 is arranged in the optical path channel 112. The drainage channel 113 allows liquid to flow from the proximal end of the catheter assembly 100 to the distal end of the catheter assembly 100, and is used solely for the discharge of liquid inside the human body. For example, when used in prostate surgery, the drainage channel 113 is used for the discharge of urine in the bladder.

[0047] Functional decoupling and collaborative optimization are achieved by physically isolating the drainage channel 113 (liquid discharge), the balloon channel 111 (balloon body 200 control) and the optical path channel 112 (optical fiber 320 transmission). On the one hand, the expansion and contraction of the balloon body 200 can be independently and accurately controlled, and the balloon channel 111 with a suitable inner diameter is selected to improve the expansion efficiency of the balloon body 200. On the other hand, the optical path channel 112 with a smaller inner diameter than the balloon channel 111 is selected to stabilize the position of the light output section 322 of the optical fiber 320 and reduce light intensity fluctuations.

[0048] In one embodiment, in combination Figure 4 In the cross section of the catheter assembly 100, the optical path channel 112 is annularly arranged around the circumference of the lumen 110, and the light output section 322 is spirally arranged in the optical path channel 112. Based on this, the spiral annular light output section 322 can firstly improve the circumferential uniformity of the light output and reduce the standard deviation of the circumferential light intensity distribution; secondly, it increases the illumination coverage area, reduces dark spots or bright spots, and increases the effective light output length by 3-5 times compared with the straight line design, and is close to the outer periphery of the catheter assembly 100, shortening the optical path and further improving the brightness; finally, it improves the compressive strength of the catheter assembly 100 and the light output section 322, and avoids the optical path deviation caused by the friction of the instrument during laparoscopic surgery.

[0049] In one embodiment, in combination Figure 7 In the cross section of the catheter assembly 100, the optical path channel 112 is located in the middle of the lumen 110, and the light-emitting section 322 is linear and extends along the length direction of the optical path channel 112. Based on this, the light-emitting section 322 is located in the middle of the catheter assembly 100, and the light radiates from the center of the catheter assembly 100 to the surroundings, eliminating the "single-side overexposure" problem caused by the eccentric light field. At the same time, the linear light-emitting section 322 has a small outer diameter, which is conducive to the size reduction design of the catheter assembly 100.

[0050] In this embodiment, the proximal end of the optical path channel 112 is closed to isolate the micro-vibration caused by the liquid flow.

[0051] Specifically, combined Figure 8The lumen 110 is integrally formed with a partition wall 114 to separate the inside of the lumen 110 into a balloon channel 111, an optical channel 112, and a drainage channel 113. The partition wall 114 is integrally formed, seamlessly connected, has no interface stress concentration point, does not require assembly space and accommodates connection structures, is conducive to the ultra-thin diameter design of the catheter assembly 100, and the shapes and positions of the balloon channel 111, the optical channel 112, and the drainage channel 113 are fixed, with zero leakage risk.

[0052] In one embodiment, in combination Figure 8 The catheter assembly 100 includes a first light-transmitting tube 115, a third light-transmitting tube 117, and a second light-transmitting tube 116 which are nested from outside to inside. A balloon channel 111 is formed between the first light-transmitting tube 115 and the third light-transmitting tube 117, a drainage channel 113 is formed between the third light-transmitting tube 117 and the second light-transmitting tube 116, and an optical path channel 112 is formed inside the second light-transmitting tube 116. Based on this, the optical path channel 112 is centrally arranged and has a small size, which is conducive to the central arrangement of the optical fiber 320, and is conducive to uniform light emission in the circumferential direction, ensuring that the optical signal is not distorted; the balloon channel 111 and the drainage channel 113 are annular channels with a large area, which is conducive to uniform and rapid flow of fluid.

[0053] Optionally, the first light-transmitting tube 115, the third light-transmitting tube 117 and the second light-transmitting tube 116 can be transparent silicone tubes. The silicone tube has a transmittance of 85%-99% for visible light, good biocompatibility, and a bending resistance life of up to 100,000 cycles, which is conducive to smooth passage through blood vessels or urethra.

[0054] Optionally, at least one of the first light-transmitting tube 115 , the third light-transmitting tube 117 and the second light-transmitting tube 116 is provided with a light-uniform surface 130 in the form of a frosted structure or the like corresponding to the light-emitting segment 322 , so as to improve the uniformity of light emission.

[0055] Optionally, combined Figure 5 The first light-transmitting tube 115 has a liquid guide port 118 on its side, and the tube cavity 110 further includes a liquid guide channel 119 that seals and connects the liquid guide port 118 and the liquid discharge channel 113. The liquid guide channel 119 forms a low-resistance liquid passage, which facilitates rapid discharge of body fluids. Meanwhile, the liquid guide port 118 is located at the proximal side of the first light-transmitting tube 115, rather than at the end. The end of the catheter assembly 100 maintains good rigidity, which improves the passability of the catheter assembly 100 in the blood vessel or urethra.

[0056] In some embodiments, in combination Figure 8 The lumen 110 also includes a drug administration channel 1110, which prevents the drug from being contaminated by physically isolating the drug administration channel 1110, the drainage channel 113 (liquid discharge), the balloon channel 111 (controlled by the balloon body 200) and the optical path channel 112 (transmission by the optical fiber 320).

[0057] In some embodiments, the catheter assembly 100 is integrally injection molded with the optical fiber 320, and there is no need to set up a connecting structure, which is beneficial to reducing the outer diameter of the catheter assembly 100, eliminating the problem of thermal expansion coefficient differences in traditional glue bonding, and reducing the temperature drift rate. The position of the optical fiber 320 in the catheter assembly 100 is firm and accurate.

[0058] In some embodiments, in combination Figure 2 and 3 The input end of the optical fiber 320 extends out of the catheter assembly 100 and is provided with a first connector 420, and the controller 310 is provided with a second connector 430 detachably connected to the first connector 420. Based on this, the optical fiber 320 and the controller 310 are convenient to assemble and disassemble, and different types of controllers 310 and optical fibers 320 can be assembled and used, with good versatility.

[0059] In some embodiments, the controller 310 controls the light emitting section 322 to emit laser light, which is beneficial for accurately controlling the thickness of surgical resection and avoiding damage to normal tissue. For example, due to changes in the internal structure of prostate hyperplasia tissue, such as different sizes of alveoli, glandular epithelial stacking in a stratified epithelial-like pattern, and obvious and irregular proliferation of interstitial cells, the proliferation and disordered arrangement of cells in prostate hyperplasia tissue cause the light to be partially absorbed or attenuated when passing through, resulting in slight changes in the optical path difference. The laser has high coherence. After passing through prostate hyperplasia tissue, the brightness is low due to refraction and attenuation. After the prostate hyperplasia tissue is removed, the laser light passes through the normal prostate tissue and the brightness is brighter, which can accurately indicate that the surgical resection is complete and avoid continued resection causing urethral damage.

[0060] In some embodiments, in combination Figure 2 and Figure 3 The controller 310 includes a housing 311, a light source generator 312, and a control board 313. The housing 311 is located outside the first light-transmitting tube 115. The control board 313 and the light source generator 312 are installed inside the housing 311. The light source generator 312 is connected to the optical fiber 320. The control board 313 is used to control the light source generator 312 to generate light. Based on this, the controller 310 including large-sized components such as the light source generator 312 is set outside the catheter assembly 100. On the one hand, the outer diameter of the catheter assembly 100 is greatly reduced. On the other hand, the replacement and operation of components such as the light source are facilitated, and the light source generator 312 is prevented from being located inside the catheter assembly 100, thereby preventing thermal damage to human tissue.

[0061] In one embodiment, in combination Figure 2 and Figure 3The controller 310 also includes a power adjustment component 314, which is electrically connected to the control board 313. The power adjustment component 314 is used to adjust the optical power of the light source generator 312, and then adjust the brightness of the light generated by the light source generator 312. The brightness of the light output section 322 can be flexibly adjusted according to different body shapes and different tissue thicknesses to accurately mark the surgical area.

[0062] In one embodiment, in combination Figure 2 and Figure 3 The light source generator 312 includes lamp beads of multiple colors, and the controller 310 also includes a color adjustment member 315. The color adjustment member 315 is electrically connected to the control board 313. The color adjustment member 315 is used to switch multiple lamp beads so that the light source generator 312 generates light of different colors. Different colors of light have different penetrating power. The wavelength is automatically switched according to the intraoperative tissue type (such as blood vessels / tumors) and tissue thickness to optimize the marking brightness. For example, in vascular development, the color adjustment component 315 is used to control the light source generator 312 to produce green light, and in marking deep tissue, the color adjustment component 315 is used to control the light source generator 312 to produce red light; for children with thinner tissue, the color adjustment component 315 is used to control the light source generator 312 to produce blue-green light in the band of 450nm-550nm and a penetration depth of 1mm-2mm to avoid damaging deep sensitive tissues; for adults with thicker tissue, the color adjustment component 315 is used to control the light source generator 312 to produce infrared light in the band of 800nm-1500nm and a penetration depth of 5mm-10mm to enhance the development of deep lesions.

[0063] Specifically, the light source generator 312 integrates a six-color high-density LED / laser chip array, supports a spectral range of 470 nm -1550 nm, and achieves millisecond-level light color switching through the color adjustment component 315.

[0064] In some embodiments, in combination Figure 3 and Figure 4 The device for locating the tissue in the body cavity also includes a metal sensor, which includes a metal sensing coil 410 and a signal converter. The signal converter is integrated in the controller 310. The metal sensing coil 410 is located on the side of the light-emitting section 322 away from the balloon body 200. The metal sensing coil 410 is electrically connected to the signal converter through a wire. Based on this, on the one hand, the outer diameter of the metal sensing coil 410 is small, which is conducive to the miniaturization design of the catheter assembly 100, and the larger signal converter is integrated into the controller 310. On the other hand, the metal sensing coil 410 can timely sense the distance of the metal surgical tool, which is conducive to accurately controlling the surgical resection thickness and avoiding damage to normal tissue.

[0065] Optionally, the metal sensing coil 410 has a diameter of 1.5 mm and an adjustable frequency of 1-10 MHz, and can detect iron / nickel / cobalt alloys within a range of 5 mm (sensitivity 0.1 mm³). The signal converter is integrated in the controller 310, with a response time of <0.1 ms, converting the electromagnetic signal into digital positioning coordinates (accuracy ±50 μm), and the conductor ultra-fine silver nanowire (diameter 20 μm, impedance <0.1 Ω) is resistant to stretching and electromagnetic interference, ensuring signal stability during surgery.

[0066] In one embodiment, in combination Figure 2 and Figure 3 The device for locating the tissue in the body cavity also includes a spectrum measurement unit 500. The light emitted by the light-emitting section 322 is reflected by the shielding object to form a return light. The light-emitting section 322 receives the return light and transmits the return light to the spectrum measurement unit 500. The spectrum measurement unit 500 is used to analyze the phase delay and intensity attenuation of the return light. Based on this, by utilizing the characteristic of the optical fiber 320 that can transmit light, the light can be recovered and analyzed whether the light passes through the diseased tissue, which is conducive to accurately controlling the thickness of surgical resection and avoiding damage to normal tissue.

[0067] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A device for locating tissue in a body cavity, characterized in that: include: A catheter assembly, wherein the catheter assembly has a lumen, and a proximal end of the catheter assembly has a first through hole, wherein the first through hole is in communication with the lumen; A balloon body, which is disposed at the proximal end of the catheter assembly and is communicated with the first through hole; A light-emitting component, the light-emitting component includes a controller and an optical fiber, the input end of the optical fiber is connected to the controller, the output end of the optical fiber is arranged in the lumen, the output end of the optical fiber is provided with a light-emitting section on the side of the proximal end of the balloon body away from the catheter assembly, and the light-emitting section extends along the length direction of the catheter assembly; the light emitted by the controller is transmitted to the light-emitting section through the input end of the optical fiber, and is emitted through the catheter assembly.

2. The device for locating body cavity tissue according to claim 1, characterized in that: The outer diameter of the light-emitting section gradually decreases in a direction away from the input end of the optical fiber; and / or the length of the light-emitting section is 30 mm to 50 mm.

3. The device for locating body cavity tissue according to claim 1, characterized in that: The lumen includes a balloon channel, an optical path channel and a drainage channel which are independent of each other. The proximal end of the balloon channel is connected to the first through hole. The optical fiber is arranged in the optical path channel. The drainage channel is used for allowing liquid to flow from the proximal end of the catheter assembly to the distal end of the catheter assembly.

4. The device for locating body cavity tissue according to claim 3, characterized in that: In the cross section of the catheter assembly, the optical path is located in the middle of the tube cavity, and the light-emitting section is linearly extended along the length direction of the optical path; Alternatively, in the cross section of the catheter assembly, the optical path channel is annularly arranged around the circumference of the tube cavity, and the light emitting section is spirally arranged in the optical path channel.

5. The device for locating body cavity tissue according to claim 3, characterized in that: The catheter assembly includes a first light-transmitting tube, a third light-transmitting tube, and a second light-transmitting tube which are nested in sequence from the outside to the inside. The balloon channel is formed between the first light-transmitting tube and the third light-transmitting tube, the drainage channel is formed between the third light-transmitting tube and the second light-transmitting tube, and the interior of the second light-transmitting tube forms the light path channel.

6. The device for locating body cavity tissue according to claim 1, characterized in that: The catheter assembly is integrally injection molded with the optical fiber, and / or the input end of the optical fiber extends out of the catheter assembly and is provided with a first connector, and the controller is provided with a second connector detachably connected to the first connector.

7. The device for locating body cavity tissue according to claim 1, characterized in that: The controller includes a housing, a light source generator and a control board. The control board and the light source generator are installed inside the housing. The light source generator is connected to the input end of the optical fiber. The control board is used to control the light source generator to generate light.

8. The device for locating body cavity tissue according to claim 7, characterized in that: The controller further comprises a power adjustment member, the power adjustment member is electrically connected to the control board, and the power adjustment member is used to adjust the optical power of the light source generator; And / or, the light source generator includes lamp beads of multiple colors, and the controller also includes a color adjustment component, which is electrically connected to the control board, and the color adjustment component is used to switch the multiple lamp beads so that the light source generator generates light of different colors.

9. The device for locating body cavity tissue according to any one of claims 1 to 8, characterized in that: The device for locating the in-body cavity tissue further comprises a metal sensor, the metal sensor comprises a metal sensing coil and a signal converter, the signal converter is integrated in the controller, the metal sensing coil is located on a side of the light emitting section away from the balloon, and the metal sensing coil is electrically connected to the signal converter via a wire; Alternatively, the device for locating intracavitary tissue in the body also includes a spectral measurement unit. The light emitted by the light emitting segment is reflected by an obstruction to form a return light. The light emitting segment receives the return light and transmits the return light to the spectral measurement unit. The spectral measurement unit is used to analyze the phase delay and intensity attenuation of the return light.

10. The device for locating body cavity tissue according to any one of claims 1 to 8, characterized in that: The outer periphery of the light emitting section and / or the catheter assembly is provided with a light uniforming surface for uniformly dispersing the light.

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