Solvent-free hot melt adhesive capsicum paste and preparation method thereof

Abstract

The invention relates to the technical field of hot melt adhesive capsicum paste, and discloses a solvent-free hot melt adhesive capsicum paste, which comprises capsaicin, borneol, mint, glycerol, a cross-linking agent, ethanol and water. The invention relates to an analgesic gel, which is prepared from the following raw materials in parts by weight: 9.5 to 19.5 parts of capsaicin, 3.3 to 6.7 parts of borneol, 4.7 to 6.3 parts of mint, 6.6 to 8.4 parts of glycerol, 13.4 to 15.6 parts of cross-linking agent, 12.5 to 16.5 parts of ethanol, 11.2 to 15.8 parts of complex gum, 10.8 to 13.2 parts of gelatin and 6 to 30 parts of water, the analgesic effect is achieved by stimulating pain fiber endings to release nerve media, the action is rapid and lasting, and the analgesic gel is suitable for treating various chronic pains; capsaicin also has a wide anti-inflammatory effect, has an anti-inflammatory effect on inflammatory cells, and can inhibit the activity of macrophages, relieve inflammatory response, inhibit pain response and improve the immune function of the body; capsaicin is beneficial to promoting blood circulation, increasing blood flow volume, relieving vasospasm and maintaining blood pressure to be stable.

Description

Technical Field

[0001] The invention relates to the technical field of hot melt adhesive chili paste, in particular to a solvent-free hot melt adhesive chili paste and a preparation method thereof. Background Art

[0002] External treatment of traditional Chinese medicine has a long history in my country and is widely used, including acupuncture, Chinese medicine plasters, Chinese medicine fumigation, acupoint injection, acupoint thread embedding and other therapies. A review of the literature in the past 10 years shows that external treatment of traditional Chinese medicine has significant efficacy, few side effects, is economical and convenient for rheumatoid arthritis, and has a very broad application prospect, which is worthy of in-depth promotion and research.

[0003] Ankle sprains are common in sports injuries. According to Western medicine theory, they belong to the category of soft tissue injuries, especially in various intense sports, the incidence rate is as high as 80% of the body's joint injuries. Traditional Chinese medicine believes that ankle injuries belong to the category of tendon injuries, and the syndrome is "Qi stagnation and blood stasis". After a sudden sprain, both Qi and blood are injured, and blood overflows from the veins and stagnates locally, gradually forming a syndrome of blood stasis and Qi stagnation, which is its basic pathological change. In the treatment practice of ankle sprains, traditional Chinese medicine has a definite effect and has accumulated rich experience.

[0004] Capsaicin is an active ingredient extracted from the ripe fruit of the Solanaceae plant pepper, and belongs to the amide class of compounds. In addition to being used as a condiment in the food industry, capsaicin also has analgesic, anti-inflammatory, antipruritic, bactericidal, anti-rheumatic, and hair regeneration effects. There are a variety of topical pharmaceutical preparations such as patches, sprays, and ointments. Capsaicin cream is widely used to treat arthritis, muscle pain, back pain, sports sprains, and post-herpetic neuralgia. Therefore, we propose a solvent-free hot melt adhesive capsicum cream and a preparation method thereof. Summary of the invention

[0005] The purpose of the present invention is to provide a solvent-free hot melt adhesive chili paste and a preparation method thereof, which solves the problems raised in the background technology.

[0006] The embodiment of the present application provides a solvent-free hot melt adhesive chili paste, including capsaicin, borneol, mint, glycerin, a cross-linking agent, ethanol and water, and the percentages of the above-mentioned raw materials are capsaicin (9.5-19.5) parts: borneol (3.3-6.7) parts: mint (4.7-6.3) parts: glycerin (6.6-8.4) parts: cross-linking agent (13.4-15.6) parts: ethanol (12.5-16.5) parts: composite glue (11.2-15.8) parts: gelatin (10.8-13.2) parts: water (6-30) parts.

[0007] Furthermore, the capsaicin is an effective ingredient extracted from mature peppers.

[0008] Furthermore, the cross-linking agent is composed of triallyl cyanurate.

[0009] Furthermore, the composite rubber is composed of natural rubber, synthetic resin, plasticizer and filler.

[0010] Furthermore, the synthetic resin is ethylene vinyl acetate copolymer.

[0011] Furthermore, the plasticizer is at least one of stearic acid, styrene-butadiene rubber, butadiene rubber, and isoprene rubber.

[0012] Furthermore, the filler is at least one of zinc oxide, carbon black or a peptizer.

[0013] A method for preparing a solvent-free hot melt adhesive chili paste, the specific steps are as follows:

[0014] Step 1: Extract appropriate amount of capsaicin from ripe peppers;

[0015] Step 2: Mix capsaicin and gelatin, put them into a mixing tank after they are evenly mixed, stir them in cold water for 3-6 minutes to make them completely mixed with the water, and then gradually heat the mixing tank and continue stirring during heating;

[0016] Step 3, sieving the uniform solution prepared in step 2 to remove the kaolin that is not evenly dispersed;

[0017] Step 4, adding composite glue, borneol, mint, glycerol, crosslinking agent and ethanol in sequence to the sieved solution in step 3;

[0018] Step 5, putting the mixed liquid in step 4 into a constant temperature stirring tank and stirring for 4-10 minutes;

[0019] Step six, allowing the mixed solution stirred in step five to stand at a constant temperature to obtain a solvent-free hot melt adhesive chili paste.

[0020] Compared with the prior art, the technical solution of this application has the following beneficial effects:

[0021] Capsaicin in the present invention is a thermal hormone, which can release neurotransmitters by stimulating the endings of pain fibers to achieve analgesic effect, and the effect is rapid and lasting, and is suitable for the treatment of various chronic pains; capsaicin also has a wide range of anti-inflammatory effects, which can inhibit macrophage activity, reduce inflammatory reactions, inhibit pain reactions, and improve the body's immune function; capsaicin helps to promote blood circulation, increase blood flow, relieve vascular spasms, and maintain stable blood pressure. In addition, capsaicin can also regulate blood lipid metabolism and prevent the occurrence of cardiovascular diseases such as coronary heart disease. DETAILED DESCRIPTION

[0022] Example 1

[0023] The present invention provides a technical solution: a solvent-free hot melt adhesive chili paste, comprising capsaicin, borneol, mint, glycerin, a cross-linking agent, ethanol and water, and the percentages of the above raw materials are 9.5 parts of capsaicin: 3.3 parts of borneol: 4.7 parts of mint: 6.6 parts of glycerin: 13.4 parts of cross-linking agent: 12.5 parts of ethanol: 11.2 parts of composite glue: 10.8 parts of gelatin: 6 parts of water.

[0024] Furthermore, the capsaicin is an effective ingredient extracted from mature peppers.

[0025] Furthermore, the cross-linking agent is composed of triallyl cyanurate.

[0026] Furthermore, the composite rubber is composed of natural rubber, synthetic resin, plasticizer and filler.

[0027] Furthermore, the synthetic resin is ethylene vinyl acetate copolymer.

[0028] Furthermore, the plasticizer is at least one of stearic acid, styrene-butadiene rubber, butadiene rubber, and isoprene rubber.

[0029] Furthermore, the filler is at least one of zinc oxide, carbon black or a peptizer.

[0030] A method for preparing a solvent-free hot melt adhesive chili paste, the specific steps are as follows:

[0031] Step 1: Extract appropriate amount of capsaicin from ripe peppers;

[0032] Step 2: Mix capsaicin and gelatin, put them into a mixing tank after they are evenly mixed, stir them in cold water for 3-6 minutes to make them completely mixed with the water, and then gradually heat the mixing tank and continue stirring during heating;

[0033] Step 3, sieving the uniform solution prepared in step 2 to remove the kaolin that is not evenly dispersed;

[0034] Step 4, adding composite glue, borneol, mint, glycerol, crosslinking agent and ethanol in sequence to the sieved solution in step 3;

[0035] Step 5, putting the mixed liquid in step 4 into a constant temperature stirring tank and stirring for 4-10 minutes;

[0036] Step six, allowing the mixed solution stirred in step five to stand at a constant temperature to obtain a solvent-free hot melt adhesive chili paste.

[0037] Example 2

[0038] The present invention provides a technical solution: a solvent-free hot melt adhesive chili paste, comprising capsaicin, borneol, mint, glycerin, a cross-linking agent, ethanol and water, and the percentages of the above raw materials are 10 parts of capsaicin: 3.6 parts of borneol: 5 parts of mint: 6.9 parts of glycerin: 13.7 parts of cross-linking agent: 13 parts of ethanol: 11.5 parts of composite glue: 11.2 parts of gelatin: 9 parts of water.

[0039] Furthermore, the capsaicin is an effective ingredient extracted from mature peppers.

[0040] Furthermore, the cross-linking agent is composed of triallyl cyanurate.

[0041] Furthermore, the composite rubber is composed of natural rubber, synthetic resin, plasticizer and filler.

[0042] Furthermore, the synthetic resin is ethylene vinyl acetate copolymer.

[0043] Furthermore, the plasticizer is at least one of stearic acid, styrene-butadiene rubber, butadiene rubber, and isoprene rubber.

[0044] Furthermore, the filler is at least one of zinc oxide, carbon black or a peptizer.

[0045] A method for preparing a solvent-free hot melt adhesive chili paste, the specific steps are as follows:

[0046] Step 1: Extract appropriate amount of capsaicin from ripe peppers;

[0047] Step 2: Mix capsaicin and gelatin, put them into a mixing tank after they are evenly mixed, stir them in cold water for 3-6 minutes to make them completely mixed with the water, and then gradually heat the mixing tank and continue stirring during heating;

[0048] Step 3, sieving the uniform solution prepared in step 2 to remove the kaolin that is not evenly dispersed;

[0049] Step 4, adding composite glue, borneol, mint, glycerol, crosslinking agent and ethanol in sequence to the sieved solution in step 3;

[0050] Step 5, putting the mixed liquid in step 4 into a constant temperature stirring tank and stirring for 4-10 minutes;

[0051] Step six, allowing the mixed solution stirred in step five to stand at a constant temperature to obtain a solvent-free hot melt adhesive chili paste.

[0052] Example 3

[0053] The present invention provides a technical solution: a solvent-free hot melt adhesive chili paste, comprising capsaicin, borneol, mint, glycerin, a cross-linking agent, ethanol and water, and the percentages of the above raw materials are 10.5 parts of capsaicin: 3.9 parts of borneol: 5.3 parts of mint: 7.2 parts of glycerin: 14.1 parts of cross-linking agent: 13.3 parts of ethanol: 11.8 parts of composite glue: 11.5 parts of gelatin: 12 parts of water.

[0054] Furthermore, the capsaicin is an effective ingredient extracted from mature peppers.

[0055] Furthermore, the cross-linking agent is composed of triallyl cyanurate.

[0056] Furthermore, the composite rubber is composed of natural rubber, synthetic resin, plasticizer and filler.

[0057] Furthermore, the synthetic resin is ethylene vinyl acetate copolymer.

[0058] Furthermore, the plasticizer is at least one of stearic acid, styrene-butadiene rubber, butadiene rubber, and isoprene rubber.

[0059] Furthermore, the filler is at least one of zinc oxide, carbon black or a peptizer.

[0060] A method for preparing a solvent-free hot melt adhesive chili paste, the specific steps are as follows:

[0061] Step 1: Extract appropriate amount of capsaicin from ripe peppers;

[0062] Step 2: Mix capsaicin and gelatin, put them into a mixing tank after they are evenly mixed, stir them in cold water for 3-6 minutes to make them completely mixed with the water, and then gradually heat the mixing tank and continue stirring during heating;

[0063] Step 3, sieving the uniform solution prepared in step 2 to remove the kaolin that is not evenly dispersed;

[0064] Step 4, adding composite glue, borneol, mint, glycerol, crosslinking agent and ethanol in sequence to the sieved solution in step 3;

[0065] Step 5, putting the mixed liquid in step 4 into a constant temperature stirring tank and stirring for 4-10 minutes;

[0066] Step six, allowing the mixed solution stirred in step five to stand at a constant temperature to obtain a solvent-free hot melt adhesive chili paste.

[0067] Example 4

[0068] The present invention provides a technical solution: a solvent-free hot melt adhesive chili paste, comprising capsaicin, borneol, mint, glycerin, a cross-linking agent, ethanol and water, and the percentages of the above raw materials are 11 parts of capsaicin: 4.2 parts of borneol: 6 parts of mint: 7.5 parts of glycerin: 14.5 parts of cross-linking agent: 14.1 parts of ethanol: 12.1 parts of composite glue: 11.9 parts of gelatin: 15 parts of water.

[0069] Furthermore, the capsaicin is an effective ingredient extracted from mature peppers.

[0070] Furthermore, the cross-linking agent is composed of triallyl cyanurate.

[0071] Furthermore, the composite rubber is composed of natural rubber, synthetic resin, plasticizer and filler.

[0072] Furthermore, the synthetic resin is ethylene vinyl acetate copolymer.

[0073] Furthermore, the plasticizer is at least one of stearic acid, styrene-butadiene rubber, butadiene rubber, and isoprene rubber.

[0074] Furthermore, the filler is at least one of zinc oxide, carbon black or a peptizer.

[0075] A method for preparing a solvent-free hot melt adhesive chili paste, the specific steps are as follows:

[0076] Step 1: Extract appropriate amount of capsaicin from ripe peppers;

[0077] Step 2: Mix capsaicin and gelatin, put them into a mixing tank after they are evenly mixed, stir them in cold water for 3-6 minutes to make them completely mixed with the water, and then gradually heat the mixing tank and continue stirring during heating;

[0078] Step 3, sieving the uniform solution prepared in step 2 to remove the kaolin that is not evenly dispersed;

[0079] Step 4, adding composite glue, borneol, mint, glycerol, crosslinking agent and ethanol in sequence to the sieved solution in step 3;

[0080] Step 5, putting the mixed liquid in step 4 into a constant temperature stirring tank and stirring for 4-10 minutes;

[0081] Step six, allowing the mixed solution stirred in step five to stand at a constant temperature to obtain a solvent-free hot melt adhesive chili paste.

[0082] Example 5

[0083] The present invention provides a technical solution: a solvent-free hot melt adhesive chili paste, comprising capsaicin, borneol, mint, glycerin, a cross-linking agent, ethanol and water, and the percentages of the above raw materials are 11.5 parts of capsaicin: 4.5 parts of borneol: 6.3 parts of mint: 7.8 parts of glycerin: 14.8 parts of cross-linking agent: 14.4 parts of ethanol: 12.4 parts of composite glue: 12.2 parts of gelatin: 18 parts of water.

[0084] Furthermore, the capsaicin is an effective ingredient extracted from mature peppers.

[0085] Furthermore, the cross-linking agent is composed of triallyl cyanurate.

[0086] Furthermore, the composite rubber is composed of natural rubber, synthetic resin, plasticizer and filler.

[0087] Furthermore, the synthetic resin is ethylene vinyl acetate copolymer.

[0088] Furthermore, the plasticizer is at least one of stearic acid, styrene-butadiene rubber, butadiene rubber, and isoprene rubber.

[0089] Furthermore, the filler is at least one of zinc oxide, carbon black or a peptizer.

[0090] A method for preparing a solvent-free hot melt adhesive chili paste, the specific steps are as follows:

[0091] Step 1: Extract appropriate amount of capsaicin from ripe peppers;

[0092] Step 2: Mix capsaicin and gelatin, put them into a mixing tank after they are evenly mixed, stir them in cold water for 3-6 minutes to make them completely mixed with the water, and then gradually heat the mixing tank and continue stirring during heating;

[0093] Step 3, sieving the uniform solution prepared in step 2 to remove the kaolin that is not evenly dispersed;

[0094] Step 4, adding composite glue, borneol, mint, glycerol, crosslinking agent and ethanol in sequence to the sieved solution in step 3;

[0095] Step 5, putting the mixed liquid in step 4 into a constant temperature stirring tank and stirring for 4-10 minutes;

[0096] Step six, allowing the mixed solution stirred in step five to stand at a constant temperature to obtain a solvent-free hot melt adhesive chili paste.

[0097] Example 6

[0098] The present invention provides a technical solution: a solvent-free hot melt adhesive chili paste, comprising capsaicin, borneol, mint, glycerin, a cross-linking agent, ethanol and water, and the percentages of the above raw materials are 15 parts of capsaicin: 4.8 parts of borneol: 6.6 parts of mint: 8.1 parts of glycerin: 15.2 parts of cross-linking agent: 14.8 parts of ethanol: 12.8 parts of composite glue: 12.6 parts of gelatin: 22 parts of water.

[0099] Furthermore, the capsaicin is an effective ingredient extracted from mature peppers.

[0100] Furthermore, the cross-linking agent is composed of triallyl cyanurate.

[0101] Furthermore, the composite rubber is composed of natural rubber, synthetic resin, plasticizer and filler.

[0102] Furthermore, the synthetic resin is ethylene vinyl acetate copolymer.

[0103] Furthermore, the plasticizer is at least one of stearic acid, styrene-butadiene rubber, butadiene rubber, and isoprene rubber.

[0104] Furthermore, the filler is at least one of zinc oxide, carbon black or a peptizer.

[0105] A method for preparing a solvent-free hot melt adhesive chili paste, the specific steps are as follows:

[0106] Step 1: Extract appropriate amount of capsaicin from ripe peppers;

[0107] Step 2: Mix capsaicin and gelatin, put them into a mixing tank after they are evenly mixed, stir them in cold water for 3-6 minutes to make them completely mixed with the water, and then gradually heat the mixing tank and continue stirring during heating;

[0108] Step 3, sieving the uniform solution prepared in step 2 to remove the kaolin that is not evenly dispersed;

[0109] Step 4, adding composite glue, borneol, mint, glycerol, crosslinking agent and ethanol in sequence to the sieved solution in step 3;

[0110] Step 5, putting the mixed liquid in step 4 into a constant temperature stirring tank and stirring for 4-10 minutes;

[0111] Step six, allowing the mixed solution stirred in step five to stand at a constant temperature to obtain a solvent-free hot melt adhesive chili paste.

[0112] The above embodiment was tested for performance, and the results are shown in Table 1:

[0113]

[0114]

[0115] It can be seen from this that the solvent-free hot melt adhesive capsicum paste of the present invention has extremely high analgesic, anti-inflammatory and blood circulation promoting effects.

Claims

1. A solvent-free hot melt adhesive chili paste, characterized in that: The invention comprises capsaicin, borneol, mint, glycerin, a cross-linking agent, ethanol and water, and the percentages of the above raw materials are as follows: capsaicin (9.5-19.5) parts: borneol (3.3-6.7) parts: mint (4.7-6.3) parts: glycerin (6.6-8.4) parts: cross-linking agent (13.4-15.6) parts: ethanol (12.5-16.5) parts: composite glue (11.2-15.8) parts: gelatin (10.8-13.2) parts: water (6-30) parts.

2. The solvent-free hot melt adhesive chili paste according to claim 1, characterized in that: The capsaicin is an effective ingredient extracted from mature peppers.

3. The solvent-free hot melt adhesive chili paste according to claim 1, characterized in that: The cross-linking agent is composed of triallyl cyanurate.

4. The solvent-free hot melt adhesive chili paste according to claim 1, characterized in that: The composite rubber comprises natural rubber, synthetic resin, plasticizer and filler.

5. The solvent-free hot melt adhesive chili paste according to claim 4, characterized in that: The synthetic resin is ethylene vinyl acetate copolymer.

6. The solvent-free hot melt adhesive chili paste according to claim 4, characterized in that: The plasticizer is at least one of stearic acid, styrene-butadiene rubber, butadiene rubber and isoprene rubber.

7. The solvent-free hot melt adhesive chili paste according to claim 4, characterized in that: The filler is at least one of zinc oxide, carbon black or a peptizer.

8. The method for preparing the solvent-free hot melt adhesive chili paste according to claim 1, characterized in that: The specific steps are as follows: Step 1: Extract appropriate amount of capsaicin from mature peppers; Step 2: Mix capsaicin and gelatin, put them into a mixing tank after they are evenly mixed, stir them in cold water for 3-6 minutes to make them completely mixed with the water, and then gradually heat the mixing tank and continue stirring during heating; Step 3, sieving the uniform solution prepared in step 2 to remove the kaolin that is not evenly dispersed; Step 4, adding composite glue, borneol, mint, glycerol, crosslinking agent and ethanol in sequence to the sieved solution in step 3; Step 5, putting the mixed liquid in step 4 into a constant temperature stirring tank and stirring for 4-10 minutes; Step six, allowing the mixed solution stirred in step five to stand at a constant temperature to obtain a solvent-free hot melt adhesive chili paste.

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