Gastroscope water bag with defoaming function for micro-probe ultrasonic gastroscope as well as preparation method and application of gastroscope water bag

Abstract

The invention belongs to the technical field of gastroscope water bags, and particularly relates to a gastroscope water bag used for a micro-probe ultrasonic gastroscope and having a defoaming function and a preparation method and application of the gastroscope water bag. The water bag is prepared from the following components: 90-100 parts of concentrated natural rubber; 5-10 parts of a water-based acrylic resin emulsion; 10 to 15 parts of a waterborne polyurethane resin dispersion liquid; 1 to 2 parts of nano silicon dioxide; 5 to 10 parts of polyisoprene; 3-7 parts of dimethyl silicone oil and 3-5 parts of a polymerizing agent; and 20 to 30 parts of deionized water. The prepared air bag contains polydimethylsiloxane, bubbles on the surface of the air bag are continuously removed in the gastroscope examination process, and gastroscope examination cannot be affected even if a patient does not need to additionally drink a defoaming agent. Meanwhile, the water bag wraps the water medium required by the micro-probe inspection, so that the regionalization of the water medium is realized, the inspection of the anesthesia state can be realized, the pain of a patient is reduced, the peristalsis of the digestive tract is slowed down, the focus can be clearly exposed, the inspection time is shortened, and the inspection quality is improved.

Description

Technical Field

[0001] The invention belongs to the technical field of gastroscopic water bags, and in particular relates to a gastroscopic water bag used for a micro-probe ultrasonic gastroscope and having a defoaming function, and a preparation method and application thereof. Background Art

[0002] Micro-probe ultrasound gastroscopy is to place a miniature high-frequency ultrasound probe at the top of the endoscope. When the endoscope is inserted into the body cavity, the cavity morphology can be directly observed through the endoscope, and real-time ultrasound scanning can be performed to obtain the histological characteristics of the duct level. It is mainly used to determine: TNM staging of digestive tract malignant tumors, determine the origin and nature of digestive tract submucosal tumors, determine the degree of varicose veins and the effect of embolization treatment, and diagnose and differentially diagnose some digestive tract diseases.

[0003] At present, the most commonly used micro-probe ultrasound gastroscopy scanning method is the water filling method: directly inject degassed water and immerse the probe in water for scanning. However, this method widely used in clinical practice has serious shortcomings: 1. Patients cannot be examined under anesthesia, and they often feel severe nausea and vomiting, which is very painful. 2. Due to the severe nausea and vomiting of patients, the peristalsis of the digestive tract is accelerated, which not only makes it difficult for patients to tolerate the examination, but also the peristalsis of the digestive tract wall is too fast to retain water medium well, and the ultrasound examination cannot be completed. 3. The bubbles continuously generated during the examination interfere with the ultrasound examination, making the examination difficult and time-consuming, increasing the pain of patients and the cumbersome operation of doctors.

[0004] Therefore, there is an urgent need for a gastroscope water bag for micro-probe ultrasonic gastroscopy with defoaming function and water medium regionalization, so that the patient can be in an anesthetized state, the digestive tract can be less peristaltic, the bubble generation can be reduced, the patient's pain can be alleviated, and the doctor's operation complexity can be reduced. Summary of the invention

[0005] In view of the shortcomings of the prior art, the present invention provides a gastroscopic water bag with a defoaming function for a micro-probe ultrasonic gastroscope and a preparation method and application thereof, so as to solve the problems of the micro-probe ultrasonic gastroscope in the prior art: the water medium cannot be operated in a regionalized manner, the patient cannot be anesthetized, a large amount of defoaming agent is required before / during the gastroscopy, and the patient's pain is increased.

[0006] In order to achieve the above object, the present invention adopts the following technical solution: a gastroscopic water bag for micro-probe ultrasonic gastroscopy with defoaming function, wherein the water bag is prepared from the following components:

[0007] Concentrated natural rubber, 90-100 parts;

[0008] Water-based acrylic resin emulsion, 5-10 parts;

[0009] Aqueous polyurethane resin dispersion, 10-15 parts;

[0010] Nano silicon dioxide, 1-2 parts;

[0011] Polyisoprene, 5-10 parts;

[0012] Dimethyl silicone oil, 3-7 parts;

[0013] Polymerizing agent, 3-5 parts;

[0014] Deionized water, 20-30 parts.

[0015] Furthermore,

[0016] The polymerization agent is melamine;

[0017] The particle size of the nano silicon dioxide is 15-20 nanometers.

[0018] Furthermore, the water capsule is prepared from the following components:

[0019] Concentrated natural rubber, 90 parts;

[0020] Water-based acrylic resin emulsion, 5 parts;

[0021] Aqueous polyurethane resin dispersion, 10 parts;

[0022] Nano Silica, 1 part

[0023] Polyisoprene, 5 parts

[0024] Dimethicone, 3 parts

[0025] Polymerization agent, 3 parts

[0026] Deionized water, 20 parts.

[0027] Furthermore, the water capsule is prepared from the following components:

[0028] Concentrated natural rubber, 100 parts;

[0029] Water-based acrylic resin emulsion, 10 parts;

[0030] Aqueous polyurethane resin dispersion, 15 parts;

[0031] Nano Silica, 2 parts

[0032] Polyisoprene, 10 parts

[0033] Dimethicone, 7 parts

[0034] Polymerization agent, 5 parts

[0035] Deionized water, 30 parts.

[0036] Furthermore, the water capsule is prepared from the following components:

[0037] Concentrated natural rubber, 95 parts;

[0038] Water-based acrylic resin emulsion, 7 parts;

[0039] Aqueous polyurethane resin dispersion, 13 parts;

[0040] Nano silicon dioxide, 1.5 parts

[0041] Polyisoprene, 8 parts

[0042] Dimethicone, 5 parts

[0043] Polymerization agent, 4 parts

[0044] Deionized water, 25 parts.

[0045] A method for preparing a gastroscope water bag for a micro-probe ultrasonic gastroscope and having a defoaming function, the preparation method comprising the steps of:

[0046] (1) Mix the concentrated natural rubber, aqueous acrylic resin emulsion, aqueous polyurethane resin dispersion, nano-silica and deionized water evenly according to the components.

[0047] (2) slowly adding polyisoprene, dimethyl silicone oil and melamine to the mixed solution in (1), and reacting under stirring to obtain a composition.

[0048] (3) injecting into a mold and performing high-temperature vulcanization using a vulcanizer to prepare an airbag.

[0049] Furthermore, the stirring speed in (2) is 800-1200 r / min.

[0050] Furthermore, the reaction temperature in (2) is 70-90°C.

[0051] Furthermore, the reaction time in (2) is 1-2h.

[0052] Application of a gastroscope water bag for micro-probe ultrasonic gastroscope with defoaming function,

[0053] The water bag is used for a micro-probe ultrasonic gastroscope and is fixed to the end of the gastroscope. The water bag can wrap deionized water, thereby realizing the regionalization of the water medium, realizing the anesthesia state of the micro-probe ultrasonic gastroscope, and having the function of eliminating bubbles outside the water bag, thereby reducing interference factors in the inspection field of view, alleviating the patient's pain, realizing a comfortable endoscopic examination, and at the same time ensuring the quality of the ultrasonic gastroscopy.

[0054] The advantages of the gastroscope water bag used for micro-probe ultrasonic gastroscope and having defoaming function and its preparation method and application are as follows:

[0055] The present invention adds polyisoprene and dimethyl silicone oil to the synthetic raw materials of the airbag, and reacts to generate polydimethylsiloxane during the mixing of the raw materials. The polydimethylsiloxane has a defoaming function, and the bubbles on the surface of the airbag are continuously defoamed during the gastroscopy examination, and the patient does not need to drink additional defoaming agents, and the gastroscopy examination will not be affected. At the same time, the water bag wraps the water medium required for the microprobe inspection, realizes the regionalization of the water medium, can realize the inspection of the anesthesia state, reduce the patient's pain, slow down the peristalsis of the digestive tract, can clearly expose the lesion, shorten the inspection time, and improve the inspection quality. BRIEF DESCRIPTION OF THE DRAWINGS

[0056] Figure 1 This is a diagram showing the effect of using the airbag of an embodiment of the present invention to perform gastroscopy;

[0057] Figure 2 This is a picture showing the effect of gastroscopy using a common balloon;

[0058] Figure 3 The ultrasonic image of the ultrasonic gastroscopy using the air-balloon micro-probe of the embodiment of the present invention;

[0059] Figure 4 This is a picture showing the effect of the airbag after being filled with water according to an embodiment of the present invention; DETAILED DESCRIPTION

[0060] The specific implementation manner will be further described below in conjunction with the accompanying drawings.

[0061] The reagents and instruments in the following examples are all conventional experimental reagents and instruments.

[0062] Embodiment 1:

[0063] A gastroscope water bag for micro-probe ultrasonic gastroscope with defoaming function, the water bag is prepared from the following components:

[0064] Concentrated natural rubber, 90 parts;

[0065] Water-based acrylic resin emulsion, 5 parts;

[0066] Aqueous polyurethane resin dispersion, 10 parts;

[0067] Nano Silica, 1 part

[0068] Polyisoprene, 5 parts

[0069] Dimethicone, 3 parts

[0070] Melamine, 3 parts

[0071] Deionized water, 20 parts.

[0072] The particle size of the nano silicon dioxide is 15-20 nanometers.

[0073] A method for preparing a gastroscope water bag with defoaming function,

[0074] The steps of the preparation method include:

[0075] (1) Mix the concentrated natural rubber, aqueous acrylic resin emulsion, aqueous polyurethane resin dispersion, nano-silica and deionized water uniformly according to the components;

[0076] (2) Slowly add polyisoprene, dimethyl silicone oil and melamine to the mixed solution in (1) and react under stirring at a stirring speed of 800 r / min and a reaction temperature of 70° C. The reaction time is 1 h. A composition is obtained.

[0077] (3) injecting into a mold and performing high-temperature vulcanization using a vulcanizer to prepare an airbag.

[0078] Embodiment 2:

[0079] A gastroscope water bag with defoaming function, the water bag is prepared from the following components:

[0080] Concentrated natural rubber, 100 parts;

[0081] Water-based acrylic resin emulsion, 10 parts;

[0082] Aqueous polyurethane resin dispersion, 15 parts;

[0083] Nano Silica, 2 parts

[0084] Polyisoprene, 10 parts

[0085] Dimethicone, 7 parts

[0086] Melamine, 5 parts

[0087] Deionized water, 30 parts.

[0088] A method for preparing a gastroscope water bag with defoaming function,

[0089] The steps of the preparation method include:

[0090] (1) Mix the concentrated natural rubber, aqueous acrylic resin emulsion, aqueous polyurethane resin dispersion, nano-silica and deionized water uniformly according to the components;

[0091] (2) Slowly add polyisoprene, dimethyl silicone oil and melamine to the mixed solution in (1) and react under stirring at a stirring speed of 1000 r / min and a reaction temperature of 90° C. The reaction time is 2 h to obtain a composition.

[0092] (3) injecting into a mold and performing high-temperature vulcanization using a vulcanizer to prepare an airbag.

[0093] Example 3

[0094] A gastroscope water bag with defoaming function, the water bag is prepared from the following components:

[0095] Concentrated natural rubber, 95 parts;

[0096] Water-based acrylic resin emulsion, 7 parts;

[0097] Aqueous polyurethane resin dispersion, 13 parts;

[0098] Nano silicon dioxide, 1.5 parts

[0099] Polyisoprene, 8 parts

[0100] Dimethicone, 5 parts

[0101] Polymerization agent, 4 parts

[0102] Deionized water, 25 parts.

[0103] A method for preparing a gastroscope water bag with defoaming function,

[0104] The steps of the preparation method include:

[0105] (1) Mix the concentrated natural rubber, aqueous acrylic resin emulsion, aqueous polyurethane resin dispersion, nano-silica and deionized water evenly according to the components.

[0106] (2) Slowly add polyisoprene, dimethyl silicone oil and melamine to the mixed solution in (1) and react under stirring at a stirring speed of 900 r / min and a reaction temperature of 80° C. The reaction time is 1.5 h. A composition is obtained.

[0107] (3) injecting into a mold and performing high-temperature vulcanization using a vulcanizer to prepare an airbag.

[0108] The invention discloses an application of a gastroscope water bag used for a micro-probe ultrasonic gastroscope and having a defoaming function. The water bag is used for the micro-probe ultrasonic gastroscope, is fixed to the end of the gastroscope, and has a defoaming effect.

[0109] The polyisoprene and dimethyl silicone oil in the raw materials of the present invention generate polydimethylsiloxane under the action of the polymerizing agent melamine, and the polydimethylsiloxane is mixed in the raw materials of the air bag. The prepared air bag has the polydimethylsiloxane evenly distributed, has the defoaming ability during the gastroscopy, and can complete the gastroscopy without taking a defoaming agent.

[0110] Figure 1This is a diagram showing the effect of using the airbag prepared in this application for gastroscopy. Figure 2 This is the effect of using a common air balloon for gastroscopy. Figure 3 This is an ultrasound image of a gastroscopy using the balloon microprobe; Figure 4 This is the effect diagram after the airbag is filled with water. It can be seen from the figure that the present application can make the inspection result clear without the use of a defoaming agent. However, when using the existing airbag inspection, it is impossible to achieve the regionalization of the water medium, it is impossible to achieve ultrasonic gastroscopy under anesthesia, and there are problems such as a large number of bubbles generated and the rapid peristalsis of the digestive tract affecting the inspection effect.

[0111] The above embodiments are only for illustrating the technical concept and features of the present invention, and their purpose is to enable ordinary technicians in the field to understand the content of the present invention and implement it accordingly, and they cannot be used to limit the protection scope of the present invention. Any equivalent changes or modifications made based on the essence of the content of the present invention should be included in the protection scope of the present invention.

Claims

1. A gastroscope water bag for micro-probe ultrasonic gastroscope with defoaming function, characterized in that: The water capsule is prepared from the following components: Concentrated natural rubber, 90-100 parts; Water-based acrylic resin emulsion, 5-10 parts; Aqueous polyurethane resin dispersion, 10-15 parts; Nano silicon dioxide, 1-2 parts; Polyisoprene, 5-10 parts; Dimethyl silicone oil, 3-7 parts; Polymerizing agent, 3-5 parts; Deionized water, 20-30 parts.

2. The gastroscope water bag with defoaming function for use with a micro-probe ultrasonic gastroscope according to claim 1, characterized in that: The polymerization agent is melamine; The particle size of the nano silicon dioxide is 15-20 nanometers.

3. The gastroscopic water bag with defoaming function for use with a micro-probe ultrasonic gastroscope according to claim 1, characterized in that: The water capsule is prepared from the following components: Concentrated natural rubber, 90 parts; Water-based acrylic resin emulsion, 5 parts; Aqueous polyurethane resin dispersion, 10 parts; Nano silicon dioxide, 1 part; Polyisoprene, 5 parts; Dimethicone, 3 parts; Polymerizing agent, 3 parts; Deionized water, 20 parts.

4. The gastroscopic water bag with defoaming function for use with a micro-probe ultrasonic gastroscope according to claim 1, characterized in that: The water capsule is prepared from the following components: Concentrated natural rubber, 100 parts; Water-based acrylic resin emulsion, 10 parts; Aqueous polyurethane resin dispersion, 15 parts; Nano-silicon dioxide, 2 parts; Polyisoprene, 10 parts; Dimethicone, 7 parts; Polymerizing agent, 5 parts; Deionized water, 30 parts.

5. The gastroscope water bag with defoaming function for use with a micro-probe ultrasonic gastroscope according to claim 1, characterized in that: The water capsule is prepared from the following components: Concentrated natural rubber, 95 parts; Water-based acrylic resin emulsion, 7 parts; Aqueous polyurethane resin dispersion, 13 parts; Nano silicon dioxide, 1.5 parts; Polyisoprene, 8 parts; Dimethicone, 5 parts; Polymerizing agent, 4 parts; Deionized water, 25 parts.

6. A method for preparing a gastroscopic water bag with a defoaming function for a micro-probe ultrasonic gastroscope, characterized in that: The water bag is prepared from the components according to any one of claims 1 to 5, The steps of the preparation method include: (1) Mix the concentrated natural rubber, aqueous acrylic resin emulsion, aqueous polyurethane resin dispersion, nano-silica and deionized water uniformly according to the components; (2) slowly adding polyisoprene, dimethyl silicone oil and melamine to the mixed solution in (1), and reacting under stirring to obtain a composition. (3) The composition is prepared to obtain an airbag.

7. The method for preparing a gastroscopic water bag with a defoaming function for a micro-probe ultrasonic gastroscope according to claim 6, characterized in that: The stirring speed in (2) is 800-1200 r / min.

8. The method for preparing a gastroscopic water bag with a defoaming function for a micro-probe ultrasonic gastroscope according to claim 6, characterized in that: The reaction temperature in (2) is 150-200°C.

9. The method for preparing a gastroscopic water bag with a defoaming function for a micro-probe ultrasonic gastroscope according to claim 6, characterized in that: The reaction time in (2) is 1-2h.

10. An application of a gastroscope water bag with a defoaming function for a micro-probe ultrasonic gastroscope, wherein the water bag comprises the components according to any one of claims 1 to 5, or is prepared according to the method according to any one of claims 6 to 9, characterized in that: The water bag is used for gastroscopic ultrasound, is fixed to the end of the gastroscope, and has a defoaming effect. Deionized water is wrapped inside the water bag to regionalize the water medium, thereby realizing the anesthesia state inspection of the micro-probe ultrasonic gastroscope.

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