Protective pathogen sample collection device for infectious disease department

Abstract

The invention discloses a protection type pathogen sample collection device for the infectious disease department, and relates to the technical field of pathogen sampling appliances, the protection type pathogen sample collection device comprises a gas collection mask, a gas delivery pipe, a collection pipe, a pipe cover and a refrigeration box, the output end of the gas delivery pipe is communicated with a spiral coil, the spiral coil is integrally a conical body with a narrow upper part and a wide lower part, and the tail end of the spiral coil is closed; a plurality of exhaust holes are formed in the side wall of the spiral coil; bubbles are released at positions with different heights and diameters through the spiral coil pipe with a conical structure, the bubble spacing is increased by more than 50%, the collision fusion probability is reduced, the bubble dispersion uniformity is improved, the overload or waste of the preserving fluid in a local area is avoided, and the utilization rate of the preserving fluid is improved; and the residual holes can still maintain the gas dispersion effect by enlarging the aperture area, so that the sampling efficiency of pathogens is optimized.

Description

Technical Field

[0001] The invention relates to the technical field of pathogen sampling tools, and in particular to an infection department protective pathogen sample collection device. Background Art

[0002] At present, the sampling of pathogens of respiratory infectious diseases (such as new coronavirus, influenza virus, measles virus, tuberculosis bacillus, etc.) mostly uses swabs to scrape the mucosa of the oropharynx or nasopharynx, and then washes the virus on the swab for detection and analysis. However, this method has three disadvantages: first, since the lesions and breeding points of most pathogens of respiratory infectious diseases are in the lungs of the lower respiratory tract, the amount of pathogens retained on the mucosal walls of the oropharynx and nasopharynx of the upper respiratory tract is small, so there are not many pathogens that can be scraped; second, the surface area of ​​the swab head is very limited, and the mucosal cells and pathogens that it can adhere to are also very limited; third, in order to scrape the pathogens as much as possible, the swab must be extended as far as possible to the back of the upper respiratory tract for collection, but this will make the sampled person feel very uncomfortable, especially when using nasopharyngeal sampling. Therefore, it is urgent to invent a sampling tool that can collect a large number of pathogens discharged from the lesion breeding points of the lower respiratory tract without causing too much discomfort to the sampled person.

[0003] The Chinese invention patent with the announcement number CN111803138B in the prior art discloses a mask-type respiratory pathogen sampling device, including a mask, an air supply pipe, a collection pipe, a pipe cover, a diffuser coil, an exhaust pipe and a cold storage box. The mask is provided with a one-way valve air inlet and an air outlet; the collection pipe is detachably provided with a pipe cover, and a diffuser coil and an exhaust pipe are inserted on the pipe cover, and the diffuser coil runs through the bottom of the collection pipe; one end of the air supply pipe is connected to the air outlet of the mask, and the other end is connected to the pipe mouth of the diffuser coil; the collection pipe contains a pathogen collection and preservation liquid; the collection pipe can be adaptively placed in the cold storage box. The innovation of the above invention is that the mask intercepts the exhaled gas of the sampled person, introduces it into the diffuser coil immersed in the sampling preservation liquid, and then exhausts the gas through the micropores on the spiral diffuser coil, so that the pathogens carried in the bubbles are dissolved in the pathogen collection and preservation liquid, so as to achieve the purpose of efficiently collecting respiratory pathogens.

[0004] The above-mentioned device exhausts air through the micropores on the gas diffusion coil to dissolve the pathogens carried in the bubbles in the pathogen collection and preservation solution. However, in this process, since the diameters of the gas diffusion coils are the same, it is easy for the exhausted gas to be within the same radius, resulting in uneven gas dispersion, causing local overload or waste of the preservation solution, and easily causing the bubbles to collide and merge with each other to form larger bubbles, reducing the contact area with the preservation solution, and affecting the elution efficiency of the pathogens. Summary of the invention

[0005] The purpose of the present invention is to provide an infectious disease protection pathogen sample collection device to solve the technical problem of affecting the elution efficiency of pathogens in the prior art.

[0006] The present invention provides a protective pathogen sample collection device for infectious diseases, comprising an air collecting mask, an air supply pipe, a collecting tube, a tube cover and a cold storage box, wherein the tube cover is detachably mounted on the top of the collecting tube, one end of the air supply pipe is connected with the air collecting mask, and the other end of the air supply pipe passes through and is fixed on the tube cover, so that the user can output gas to the collecting tube through the connection of the air supply pipe, and the collecting tube is filled with a preservation liquid, the collecting tube is installed in the cold storage box, and the cold storage box is filled with a cooling liquid, a check valve is installed on the portion of the air supply pipe located on the upper side of the tube cover, a spiral coil is installed at the output end of the air supply pipe, the spiral coil is in the shape of a cone with a narrow top and a wide bottom as a whole, and the end of the spiral coil is closed, a plurality of exhaust holes are opened on the side wall of the spiral coil, and the preservation liquid in the collecting tube completely submerges the spiral coil, and an exhaust pipe is also installed on the tube cover.

[0007] Furthermore, the diameter of the spiral coil gradually increases from top to bottom, and the density of the exhaust holes on the spiral coil gradually increases from top to bottom.

[0008] Furthermore, the spiral coil is made of elastic metal, and when gas is discharged through the spiral coil, the spiral coil can be driven to expand and contract as a whole through changes in gas pressure.

[0009] Furthermore, the pitch of the spiral coil gradually increases from top to bottom.

[0010] Furthermore, the spiral coil is fixedly mounted with four elastic ropes, which are evenly distributed along the outer side of the spiral coil. When the spiral coil is in a stationary state, each of the elastic ropes is pre-stretched by 10%.

[0011] Furthermore, the elastic coefficient of the elastic rope is greater than the elastic coefficient of the spiral coil. When the spiral coil is deformed by air pressure, the elastic rope can be stretched and driven to deform.

[0012] Furthermore, each of the elastic ropes is hollow inside, and a plurality of air holes communicating with the hollow inside are formed on the side walls of the elastic ropes.

[0013] Furthermore, the direction of the air hole is consistent with the rotation direction of the spiral coil, and the elastic rope is connected to the spiral coil via a magnetic buckle.

[0014] Compared with the prior art, the beneficial effects of the present invention are:

[0015] Firstly, the present invention uses a spiral coil with a conical structure to release bubbles at different heights and diameters, increasing the distance between bubbles by more than 50%, reducing the probability of collision and fusion, improving the uniformity of bubble dispersion, avoiding overload or waste of preservation solution in local areas, and improving the utilization rate of preservation solution. In addition, the dense air diffusion holes at the bottom of the conical spiral coil can maintain the gas dispersion effect by expanding the aperture area even if some holes are blocked, thereby optimizing the sampling efficiency of pathogens.

[0016] Secondly, the present invention prolongs the contact time between the bubbles and the preservation solution through dynamic disturbance, and the vibration of the spiral coil refines the volume of the bubbles and increases the contact area between the bubbles and the preservation solution; the periodic aperture change shears the attached particles, significantly reducing the risk of mucus blocking the exhaust hole and prolonging the cleaning cycle; and no external power supply is required, and the spiral coil is only driven by gas flow energy to deform, simplifying the complexity of the device;

[0017] Thirdly, the elastic rope of the present invention bears 30% of the resetting energy for the spiral coil, which reduces the cyclic stress of the spiral coil and prolongs the service life of the spiral coil; the elastic rope provides uniform resetting force, avoids the attenuation of the deformation amplitude of the spiral coil caused by local plastic deformation, and the elastic rope with deformation vibration can disturb the preservation liquid, further increasing the elution efficiency of pathogens;

[0018] Fourthly, the present invention further reduces the volume of bubbles through jet disturbance, thereby increasing the reaction area of ​​the gas-liquid interface, and the vortex superposition effect prolongs the bubble residence time, thereby enhancing the elution efficiency of pathogens. The jet liquid of the elastic rope can flush the surface of the spiral coil, reduce the attachment of pathogens / mucus to the spiral coil, and ultimately improve the capture efficiency of pathogens. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the specific implementation methods of the present invention or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0020] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;

[0021] Figure 2 It is a sectional view of the three-dimensional structure of the present invention;

[0022] Figure 3 This is a schematic diagram of a first state of the spiral coil in the second embodiment of the present invention;

[0023] Figure 4 This is a schematic diagram of the second state of the spiral coil in the second embodiment of the present invention;

[0024] Figure 5 This is a schematic diagram of the internal structure of the collecting tube in the third embodiment of the present invention;

[0025] Figure 6 This is a schematic diagram of a first state of an elastic rope in a fourth embodiment of the present invention;

[0026] Figure 7 Schematic diagram of the second state of the elastic rope in the fourth embodiment of the present invention.

[0027] Reference numerals:

[0028] 100. Gas collecting mask; 110. Gas transmission pipe; 120. Collection pipe; 130. Refrigeration box; 200. Pipe cover; 210. Check valve; 220. Exhaust pipe; 230. Spiral coil; 240. Elastic rope; 241. Air hole. DETAILED DESCRIPTION

[0029] The technical solution of the present invention will be clearly and completely described below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0030] The components of the embodiments of the present invention generally described and shown in the drawings herein may be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely represents selected embodiments of the present invention.

[0031] Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in the field without making any creative work shall fall within the scope of protection of the present invention.

[0032] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0033] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0034] Embodiment 1, below combines Figure 1 to Figure 2 As shown, an embodiment of the present invention provides an infectious disease protective pathogen sample collection device, comprising an air collecting mask 100, an air supply pipe 110, a collection pipe 120, a tube cover 200 and a cold storage box 130, wherein the tube cover 200 is detachably mounted on the top of the collection pipe 120, one end of the air supply pipe 110 is connected to the air collecting mask 100, and the other end of the air supply pipe 110 passes through and is fixed on the tube cover 200. Through the connection of the air supply pipe 110, the user can output gas to the collection pipe 120, and the collection pipe 120 is filled with a preservation solution. When performing a sample collection operation, the user first injects the preservation solution into the collection pipe 120 until the preservation solution covers the spiral coil 230, and then installs the collection pipe 120 in the cold storage box 130, and then wears the air collecting mask 100. The gas exhaled by the user enters the collection pipe 120 through the air supply pipe 110 and contacts with the preservation solution. The preservation solution elutes the pathogens in the gas, and the eluted gas passes through the exhaust pipe 220. The gas discharged from the exhaust pipe 220 may be discharged after further treatment because the preservation solution may not be able to completely elute the pathogens. This is a prior art and will not be described in detail. The collecting pipe 120 is installed in a cold storage box 130, which is filled with coolant. A check valve 210 is installed on the upper side of the gas supply pipe 110, and a spiral coil 230 is installed at the output end of the gas supply pipe 110. The spiral coil 230 is a cone-shaped body with a narrow top and a wide bottom as a whole, and the end of the spiral coil 230 is closed. A plurality of exhaust holes 241 (not shown in the figure) are provided on the side wall of the spiral coil 230. The bubbles released from the exhaust holes 241 at different diameter positions are naturally dispersed in the preservation solution due to the differences in height and flow rate, so as to avoid the bubbles from converging and merging. The preservation solution in the collecting pipe 120 completely submerges the spiral coil 230, and an exhaust pipe 220 is also installed on the tube cover 200.

[0035] Preferably, the diameter of the spiral coil 230 gradually increases from top to bottom. After the gas enters the conical spiral coil 230, the flow velocity of the gas in the spiral coil 230 gradually decreases due to the gradual increase in the diameter, the pressure distribution is more uniform, and the density of the exhaust holes 241 on the spiral coil 230 gradually increases from top to bottom.

[0036] The technical solutions in the above embodiments of the present application have at least the following technical effects or advantages:

[0037] The spiral coil 230 with a conical structure allows bubbles to be released at different heights and diameters, increasing the distance between bubbles by more than 50%, reducing the probability of collision and fusion, improving the uniformity of bubble dispersion, avoiding overload or waste of preservation fluid in local areas, and improving the utilization rate of preservation fluid. In addition, the conical spiral coil 230 has a dense design of gas diffusion holes 241 at the bottom. Even if some holes are blocked, the remaining holes can still maintain the gas dispersion effect by expanding the aperture area, thereby optimizing the sampling efficiency of pathogens.

[0038] Example 2: In order to further increase the utilization rate of the preservation solution and improve the elution effect of the pathogen, Figure 3-Figure 4 As shown, further improvements are made to the first embodiment:

[0039] Preferably, the spiral coil 230 is made of elastic metal, which is nickel-titanium alloy, and the surface of the spiral coil 230 is covered with a medical-grade silicone layer. When the gas is discharged through the spiral coil 230, the change in air pressure can drive the spiral coil 230 to expand and contract as a whole. At this time, the preservation liquid can be eddied to a certain extent, and the pathogens can be accelerated to detach from the bubble surface through physical disturbance. In the process of deformation of the spiral coil 230, the exhaust holes 241 on the spiral coil 230 will also undergo periodic deformation, which can further refine the bubbles and prevent the exhaust holes 241 from being blocked.

[0040] Preferably, the pitch of the spiral coil 230 gradually increases from top to bottom. By changing the pitch of the spiral coil 230 , the air pressure can be better converted into the telescopic power of the spiral coil 230 .

[0041] The technical solutions in the above embodiments of the present application have at least the following technical effects or advantages:

[0042] The contact time between the bubbles and the preservation solution is prolonged through dynamic disturbance, and the vibration of the spiral coil 230 refines the volume of the bubbles and increases the contact area between the bubbles and the preservation solution; the periodic aperture change shears the attached particles, significantly reducing the risk of mucus clogging the exhaust holes 241 and extending the cleaning cycle; and no external power source is required, and the spiral coil 230 is driven to deform only by the gas flow energy, which simplifies the complexity of the device.

[0043] Embodiment 3: To prevent the spiral coil 230 from being deformed repeatedly over a long period of time, which may cause metal fatigue and shorten the service life, Figure 5 As shown, further improvements are made to the second embodiment:

[0044] Preferably, an elastic rope 240 is also fixedly mounted on the spiral coil 230, and the surface of the elastic rope 240 is coated with a nano-ceramic coating to prevent corrosion by the preservation solution. There are four elastic ropes 240, and the four elastic ropes 240 are evenly distributed along the outer side of the spiral coil 230. When the spiral coil 230 is in a stationary state, each of the elastic ropes 240 is pre-stretched by 10%, and a slight tension is maintained when the spiral coil 230 is stationary to avoid relaxation interference; when the gas pressure drives the spiral coil 230 to stretch, the elastic rope 240 stretches synchronously to store elastic potential energy; when the gas pressure decreases, the elastic rope 240 contracts to provide a reset elastic force to reduce the deformation dependence of the nickel-titanium alloy.

[0045] Preferably, the elastic coefficient of the elastic rope 240 is greater than the elastic coefficient of the spiral coil 230. When the spiral coil 230 is deformed by air pressure, the elastic rope 240 can be stretched and driven to deform.

[0046] The technical solutions in the above embodiments of the present application have at least the following technical effects or advantages:

[0047] The elastic rope 240 bears 30% of the restoring energy for the spiral coil 230, reducing the cyclic stress of the spiral coil 230 and extending the service life of the spiral coil 230; the elastic rope 240 provides a uniform restoring force to avoid the attenuation of the deformation amplitude of the spiral coil 230 caused by local plastic deformation, and the deformed and vibrated elastic rope 240 can disturb the preservation solution, further increasing the elution efficiency of the pathogens.

[0048] Example 4: In order to further improve the elution and extraction efficiency of pathogens, Figure 6-Figure 7 As shown, further improvements are made to the third embodiment:

[0049] Preferably, each of the elastic ropes 240 is hollow inside, and a plurality of air holes 241 communicating with the hollow inside are formed on the side wall of the elastic rope 240 .

[0050] Preferably, the direction of the air hole 241 is consistent with the rotation direction of the spiral disk, and the elastic rope 240 is connected to the spiral coil 230 by a magnetic buckle (not shown in the figure). Since the preservation fluid will enter the elastic rope 240, the elastic rope 240 will be contaminated after use. Therefore, the elastic rope 240 is connected to the spiral coil 230 by a magnetic buckle to facilitate the subsequent replacement of the elastic rope 240.

[0051] The technical solutions in the above embodiments of the present application have at least the following technical effects or advantages:

[0052] The jet disturbance further reduces the bubble volume, thereby increasing the gas-liquid interface reaction area, and the vortex superposition effect prolongs the bubble residence time, thereby enhancing the elution efficiency of pathogens. The jet liquid of the elastic rope 240 can flush the surface of the spiral coil 230, reducing the attachment of pathogens / mucus to the spiral coil 230, and ultimately improving the capture efficiency of pathogens.

[0053] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A protective pathogen sample collection device for infectious diseases, comprising a gas collecting mask (100), an air supply pipe (110), a collection pipe (120), a pipe cover (200) and a cold storage box (130), wherein the pipe cover (200) is detachably mounted on the top of the collection pipe (120), one end of the air supply pipe (110) is connected to the gas collecting mask (100), and the other end of the air supply pipe (110) passes through and is fixed on the pipe cover (200), and the user can output gas to the collection pipe (120) through the connection of the air supply pipe (110), and the collection pipe (120) is filled with a preservation liquid, and the collection pipe (120) is installed in the cold storage box (130), and the cold storage box (130) is filled with a cooling liquid, characterized in that: A check valve (210) is installed on the portion of the gas delivery pipe (110) located on the upper side of the pipe cover (200). The output end of the gas delivery pipe (110) is connected to a spiral coil (230). The spiral coil (230) is in the shape of a cone that is narrow at the top and wide at the bottom. The end of the spiral coil (230) is closed. A plurality of exhaust holes (241) are provided on the side wall of the spiral coil (230). The preservation liquid in the collection pipe (120) completely covers the spiral coil (230). An exhaust pipe (220) is also installed on the pipe cover (200).

2. The infectious disease protection pathogen sample collection device according to claim 1, characterized in that: The diameter of the spiral coil (230) gradually increases from top to bottom, and the density of the exhaust holes (241) on the spiral coil (230) gradually increases from top to bottom.

3. The infectious disease protection pathogen sample collection device according to claim 1, characterized in that: The spiral coil (230) is made of elastic metal, and when gas is discharged through the spiral coil (230), the spiral coil (230) can be driven to expand and contract as a whole due to changes in gas pressure.

4. The infectious disease protection pathogen sample collection device according to claim 3, characterized in that: The pitch of the spiral coil (230) gradually increases from top to bottom.

5. The infectious disease protection pathogen sample collection device according to claim 3, characterized in that: The spiral coil (230) is also fixedly mounted with an elastic rope (240), wherein there are four elastic ropes (240) which are evenly distributed along the outer side of the spiral coil (230), and when the spiral coil (230) is in a stationary state, each of the elastic ropes (240) is pre-stretched by 10%.

6. The infectious disease protection pathogen sample collection device according to claim 5, characterized in that: The elastic coefficient of the elastic rope (240) is greater than the elastic coefficient of the spiral coil (230), and when the spiral coil (230) is deformed by air pressure, the elastic rope (240) can be stretched and the elastic rope (240) can be driven to deform.

7. The infectious disease protection pathogen sample collection device according to claim 5, characterized in that: Each of the elastic ropes (240) is hollow inside, and a plurality of air holes (241) communicating with the hollow inside are formed on the side wall of the elastic rope (240).

8. The infectious disease protection pathogen sample collection device according to claim 7, characterized in that: The direction of the air hole (241) is consistent with the rotation direction of the spiral coil (230), and the elastic rope (240) is connected to the spiral coil (230) via a magnetic buckle.

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