Sample sorting structure, sample sorting method and related equipment
Patent Information
- Application Number
- CN202380073404.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-01-03
- Publication Date
- 2025-05-23
AI Technical Summary
In the existing technology, the sorting efficiency of cell samples is low, the sample residual amount is high, and manual intervention is required, resulting in high costs and the inability to realize automation.
A sample sorting structure is designed, which adopts a centrifugal and extrusion method, and uses a rotating drive component and a flat push drive component to operate synchronously to achieve sample stratification and sorting, reduce the amount of sample residue, and improve the efficiency of automated sorting.
It improves sample sorting efficiency, improves sample utilization, reduces costs, realizes automated sorting, and reduces manual intervention.
Smart Images

Figure CN120035479A_ABST
Abstract
Description
Sample sorting structure, sample sorting method and related equipment Technical Field
[0001] The present application relates to the technical field of sample sorting, and in particular to a sample sorting structure, a sorting device, a sample sorting fluid system, a sample culture system, and a sample sorting method. Background Art
[0002] Currently, the separation of samples, such as cells, typically requires a centrifuge. This separation of centrifugation and separation often results in low sorting efficiency, and the desired cells can be mixed with other cells, reducing the effectiveness of testing and treatment. Furthermore, the entire process requires manual intervention, making automation impossible and resulting in high labor costs.
[0003] Furthermore, although there are sorting equipment that can separate while centrifuging, the samples after centrifugation need to be pumped out to different containers through pipelines under the action of pumps. This is because the samples in the centrifugal chamber cannot be completely discharged by relying solely on centrifugal force, and the sample residue is high, which leads to a more complex structure of the centrifugal chamber. In addition, as a consumable material, the centrifugal chamber is relatively expensive.
[0004] In summary, how to improve sample sorting efficiency, increase sample utilization, and reduce costs is an urgent problem to be solved by those skilled in the art.
[0005] Application Contents
[0006] This application proposes a sample sorting structure, a sorting device, a sample sorting fluid system, a sample culture system and a sample sorting method to improve sample sorting efficiency, increase sample utilization and reduce costs.
[0007] In order to achieve the above objectives, this application provides the following technical solutions:
[0008] In a first aspect, the present application provides a sample sorting structure, comprising:
[0009] a centrifugal chamber assembly having a centrifugal inner cavity;
[0010] a rotary drive assembly for driving the centrifugal chamber assembly to rotate;
[0011] a core shaft, the core shaft being synchronously rotatably connected to the centrifugal chamber assembly, one end of the core shaft extending into the centrifugal inner cavity and being movable relative to the centrifugal inner cavity;
[0012] A squeezing platform fixed to one end of the core shaft extending to the centrifugal cavity, the squeezing platform being used to load the sample bag to be sorted and being driven by the core shaft to move toward or away from the end of the centrifugal cavity for squeezing the sample bag to be sorted;
[0013] A horizontal push drive assembly drives the core shaft to move in the centrifugal cavity, and the horizontal push drive assembly is rotatably connected to the core shaft.
[0014] In some possible solutions of the present application, one end of the centrifugal cavity used for squeezing the sample bag to be sorted is arranged in parallel with one end of the squeezing platform used for loading the sample bag to be sorted.
[0015] In some possible solutions of the present application, the centrifugal chamber assembly includes:
[0016] a centrifugal chamber, wherein the inner cavity of the centrifugal chamber is the centrifugal inner cavity;
[0017] The shaft sleeve is mounted on the centrifugal chamber, the rotary drive assembly is in transmission connection with the shaft sleeve, the core shaft is sleeved in the shaft sleeve, and one end extends out of the shaft sleeve and enters the centrifugal cavity, and the other end extends out of the shaft sleeve and is in transmission connection with the push drive assembly.
[0018] In some possible solutions of the present application, the sleeve is connected to the core shaft via a spline or a key bar.
[0019] In some possible solutions of the present application, the centrifugal chamber includes a centrifugal chamber housing and a centrifugal chamber cover;
[0020] One end of the centrifugal chamber housing is open, and the centrifugal chamber cover is detachably provided at the opening of the centrifugal chamber housing;
[0021] The shaft sleeve is fixed to one end of the centrifugal chamber housing away from the opening.
[0022] In some possible solutions of the present application, a rotation-limiting protrusion is provided on the edge of the centrifugal chamber cover, and a rotation-limiting notch is provided at the top of the centrifugal chamber housing to limit the position of the rotation-limiting protrusion;
[0023] and / or
[0024] A connecting post is provided on one of the surfaces of the centrifugal chamber cover and the centrifugal chamber housing facing each other, a fastening hole is provided on the end surface of the connecting post facing the other, and the other is detachably connected to the connecting post by a fastener, and a through hole is provided on the extrusion platform to allow the connecting post to pass through;
[0025] or
[0026] The centrifugal chamber cover and the centrifugal chamber shell are respectively provided with communication holes, and the two are detachably connected by fasteners. The extrusion platform is provided with a through hole allowing the fasteners to pass through.
[0027] In some possible solutions of the present application, the centrifugal chamber assembly further includes a rotary joint, which is installed on the centrifugal chamber cover, one end of which is connected to the outlet of the sample bag to be sorted, and the other end is used for external output pipeline.
[0028] In some possible solutions of the present application, the centrifugal chamber assembly further includes a centrifugal rubber block and a joint fixing member;
[0029] The centrifugal rubber block is inserted into the rubber block fixing through hole provided on the centrifugal chamber cover, and the centrifugal rubber block is provided with a mounting hole for mounting one end of the rotary joint, and the sample bag to be sorted in the centrifugal chamber is connected to the rotary joint;
[0030] The joint fixing piece is fixed, and the other end of the rotary joint is mounted on the joint fixing piece and extends out of the joint fixing piece to be externally connected to the output pipeline.
[0031] In some possible solutions of the present application, the centrifugal chamber assembly further includes a protective cover;
[0032] The protective cover is fixed and located above the centrifugal chamber;
[0033] The connector fixing piece is mounted on the top end of the protective cover.
[0034] In some possible solutions of the present application, the protective cover is made of a transparent material;
[0035] and / or
[0036] A handle is provided on the top of the protective cover.
[0037] In some possible solutions of the present application, the extrusion platform has at least one section of cross-section that gradually decreases from an end away from the core shaft to an end close to the core shaft;
[0038] or
[0039] The extrusion platform includes a first turntable supporting the sample bag to be sorted and a second turntable connected to the core shaft, the second turntable is connected to the bottom end of the first turntable, and a reinforcing rib is provided between the first turntable and the second turntable;
[0040] and / or
[0041] The core shaft is provided with a connecting disk connected to the extrusion platform.
[0042] In some possible solutions of the present application, the rotary drive assembly includes:
[0043] a first mounting seat, wherein a mounting hole is formed on the first mounting seat to allow the shaft sleeve to pass through;
[0044] a bearing seat mounted on the first mounting seat;
[0045] A first bearing is installed in the bearing seat, and the shaft sleeve is sleeved in the first bearing;
[0046] a first driver mounted on the first mounting seat;
[0047] A first transmission mechanism is respectively connected to the first driver and the shaft sleeve.
[0048] In some possible solutions of the present application, the first driver is a first motor, or the first driver includes a first motor and a first reducer transmission-connected to the first motor;
[0049] and / or
[0050] The first transmission mechanism is a transmission belt mechanism, a transmission gear mechanism or a transmission chain mechanism;
[0051] and / or
[0052] The first transmission mechanism and the bearing seat are respectively installed at two ends of the first mounting seat.
[0053] In some possible solutions of the present application, the rotary drive assembly further includes a first spacer, a second spacer, and a locking member;
[0054] The bearing group includes a first bearing and a second bearing;
[0055] The outer wall of the shaft sleeve is provided with a first limiting step, and one end of the inner ring of the first bearing facing the centrifugal chamber abuts against the first limiting step. The first spacer is sleeved outside the shaft sleeve, and one end of the first spacer facing the centrifugal chamber abuts against one end of the inner ring of the first bearing away from the centrifugal chamber.
[0056] A limiting protrusion is provided on the inner wall of the bearing seat, and an end of the outer ring of the first bearing facing away from the centrifugal chamber abuts against an end of the limiting protrusion facing the centrifugal chamber;
[0057] One end of the inner ring of the second bearing facing the centrifugal chamber abuts against one end of the first spacer sleeve facing away from the centrifugal chamber, one end of the outer ring of the second bearing facing the centrifugal chamber abuts against one end of the limiting protrusion facing away from the centrifugal chamber, the second spacer sleeve is sleeved outside the shaft sleeve, and one end facing the centrifugal chamber abuts against one end of the inner ring of the second bearing facing away from the centrifugal chamber, and the locking member is locked outside the shaft sleeve, and one end facing the centrifugal chamber abuts against one end of the second spacer sleeve facing away from the centrifugal chamber.
[0058] In some possible solutions of the present application, the push drive assembly includes: a second mounting seat; a second driver mounted on the second mounting seat; a second transmission mechanism, one end of the second transmission mechanism being transmission-connected to the second driver, and the other end of the second transmission mechanism being transmission-connected to an end of the core shaft away from the centrifugal chamber assembly, for driving the core shaft to move within the centrifugal chamber under the drive of the second driver;
[0059] or
[0060] The horizontal push drive assembly includes: a second mounting seat; a linear electric cylinder, an air cylinder, a hydraulic cylinder or an electric push rod mounted on the second mounting seat, and the core shaft is rotatably connected to the driving end of the linear electric cylinder, the air cylinder, the hydraulic cylinder or the electric push rod.
[0061] In some possible solutions of the present application, the second transmission mechanism is a rocker sliding mechanism, which includes a rocker arm, a connecting rod, a bearing chamber and a third bearing.
[0062] One end of the rocker arm is transmission-connected to the second driver, the other end of the rocker arm is hinged to one end of the connecting rod, the other end of the connecting rod is hinged to the bearing chamber, the third bearing is installed in the bearing chamber, and the end of the core shaft away from the centrifugal chamber assembly is rotatably connected to the third bearing.
[0063] The rotation axis of the rocker arm is perpendicular to the direction in which the core shaft moves in the centrifugal cavity;
[0064] or
[0065] The second transmission mechanism is a screw-nut mechanism, and the core shaft is rotatably connected to the nut of the screw-nut mechanism.
[0066] In some possible solutions of the present application, the rocker sliding mechanism further includes a first joint bearing and a second joint bearing;
[0067] One end of the first spherical bearing is threadedly connected to one end of the connecting rod, and the other end is hinged to the third bearing seat;
[0068] One end of the second joint bearing is threadedly connected to the other end of the connecting rod, and the other end is hinged to the rocker arm.
[0069] In some possible solutions of the present application, the second driver includes a second motor, a transmission shaft, and a fourth bearing;
[0070] The second motor is mounted on the second mounting seat and is in transmission connection with the transmission shaft. The transmission shaft is rotatably mounted on the second mounting seat via the fourth bearing, and the rocker arm is fixed on the transmission shaft.
[0071] In some possible solutions of the present application, the horizontal push drive assembly further includes a limit sensor;
[0072] The limit sensor is mounted on the second mounting seat and is used to detect the rotation angle of the transmission shaft.
[0073] In a second aspect, the present application provides a sorting device, comprising a base frame, a control device, and any one of the sample sorting structures described above or the sorting device described above;
[0074] The sample sorting structure and the control device are both installed on the base frame, and the control device is connected to the sample sorting structure by signal.
[0075] In a third aspect, the present application provides a sample sorting fluid system, comprising an output pipeline, a sorting holding device, and a sample sorting structure as described in any one of the above;
[0076] The outlet of the sample bag to be sorted in the sample sorting structure is connected to the inlet of the output pipeline through a rotary joint, and each outlet of the output pipeline is respectively connected to the corresponding sorting containing device.
[0077] In a fourth aspect, the present application provides a sample culture system, comprising an output pipeline, a sample culture vessel, and a sample sorting structure as described in any one of the above;
[0078] The outlet of the sample bag to be sorted in the sample sorting structure is connected to the inlet of the output pipeline through a rotary joint, and each outlet of the output pipeline is connected to the corresponding sample culture vessel.
[0079] In a fifth aspect, the present application provides a sample sorting method, comprising:
[0080] Providing a sample sorting structure as described in any one of the above;
[0081] Placing the sample bag to be sorted on the extrusion platform of the centrifugal cavity;
[0082] Starting the rotary drive assembly to drive the centrifugal chamber assembly and the core shaft to rotate synchronously, thereby driving the sample bag to be sorted to rotate and perform sample stratification;
[0083] The horizontal push drive assembly is started to drive the core shaft to move along one end close to the centrifugal cavity for squeezing the sample bag to be sorted, thereby squeezing the sample bag to be sorted and squeezing the stratified samples in the sample bag to be sorted into the corresponding device to be contained.
[0084] It can be seen from the above technical solution that the present application provides a sample sorting structure. When in use, the sample bag to be sorted is placed in the centrifugal cavity and loaded onto the extrusion platform; the rotary drive assembly is started to drive the core shaft and the centrifugal chamber assembly to rotate synchronously, thereby driving the extrusion platform to rotate, and the blood in the sample bag to be sorted is subjected to sample stratification under the action of centrifugal force; the horizontal push drive assembly is started to push the extrusion platform and the sample bag to be sorted toward one end of the centrifugal cavity for squeezing the sample bag to be sorted, thereby squeezing the different sample layers in the sample bag to be sorted into the corresponding containers, thereby achieving the sorting of the target sample. The present application adopts an automatic method of centrifugation and extrusion sorting, which improves the efficiency of sample sorting, facilitates the clean discharge of samples, improves sample utilization, and reduces costs. BRIEF DESCRIPTION OF THE DRAWINGS
[0085] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following is a brief introduction to the drawings required for the embodiments or prior art descriptions. Obviously, the drawings described below are only some examples or embodiments of the present application. For those of ordinary skill in the art, without paying any creative work, other drawings can be obtained based on the provided drawings, and the present application can also be applied to other similar scenarios based on the provided drawings. Unless it is obvious from the language context or otherwise explained, the same reference numerals in the figures represent the same structure or operation.
[0086] FIG1 is a schematic diagram of the three-dimensional structure of a sample sorting structure provided by an embodiment of the present application;
[0087] FIG2 is a schematic diagram of the main structure of a sample sorting structure provided by an embodiment of the present application;
[0088] FIG3 is a schematic diagram of the AA cross-sectional structure of FIG2 ;
[0089] FIG4 is a schematic diagram of a partial structure of FIG2 of the present application;
[0090] FIG5 is a schematic diagram of another partial structure of FIG2 of the present application;
[0091] FIG6 is a schematic diagram of the front view of a sample sorting structure provided by another embodiment of the present application;
[0092] FIG7 is a schematic cross-sectional view of the structure taken along line BB in FIG6 ;
[0093] FIG8 is a schematic diagram of the main structure of a sample sorting structure provided by another embodiment of the present application;
[0094] FIG9 is a schematic diagram of the CC cross-sectional structure of FIG8 ;
[0095] FIG10 is a schematic diagram of the three-dimensional structure of the centrifugal chamber provided in an embodiment of the present application;
[0096] FIG11 is a schematic diagram of the three-dimensional structure of the centrifugal chamber cover provided in an embodiment of the present application;
[0097] FIG12 is a schematic diagram of the three-dimensional structure of the extrusion platform provided in one direction according to an embodiment of the present application;
[0098] FIG13 is a schematic diagram of the three-dimensional structure of the extrusion platform provided in an embodiment of the present application in another direction;
[0099] FIG14 is a schematic diagram of the three-dimensional structure of an extrusion platform provided in another embodiment of the present application;
[0100] FIG15 is a schematic diagram of the three-dimensional structure of the core shaft provided in an embodiment of the present application;
[0101] FIG16 is a schematic diagram of the three-dimensional structure of the sorting equipment provided in an embodiment of the present application.
[0102] in:
[0103] Sample sorting structure 100, centrifugal chamber 101b, centrifugal chamber assembly 101, centrifugal chamber housing 101b-1, centrifugal chamber cover 101b-2, centrifugal cavity 101a, rotary drive assembly 102, core shaft 103, extrusion platform 104, push drive assembly 105, sleeve 101c, rotary joint 101d, centrifugal rubber block 101f, joint fixing piece 101e, protective cover 101g, handle 101g-1, spline 103a, rotation limiting protrusion 101b-2 a, rotation-limiting notch 101b-1a, connecting column 101b-2b, through hole 104a, accommodating groove 104b, first rotating disk 104c, second rotating disk 104d, reinforcing rib 104e, connecting disk 103b, first mounting seat 102a, bearing seat 102b, bearing assembly 102c, first driver 102d, first transmission mechanism 102e, driving pulley 101e-1, driven pulley 101e-2, transmission belt 101e-3, first spacer 102 f, second spacer 102g, locking member 102h, first bearing 102c-1, second bearing 102c-2, first limiting step 101c-1, limiting protrusion 102b-1, second mounting seat 105a, second driver 105b, second transmission mechanism 105c, rocker arm 105c-1, connecting rod 105c-2, bearing chamber 105c-3, third bearing 105c-4, first limiting protrusion 105c-3a, bearing chamber cover 105c-3b, Limiting ring 105c-3b-1, first joint bearing 105c-5, second joint bearing 105c-6, second motor 105b-1, transmission shaft 105b-2, fourth bearing 105b-3, limit sensor 105b-4, second reducer 105b-5, detection slot 103c, second limiting boss 103d, sorting equipment 1000, base frame 200, control device 300, frame body 201, mounting panel 202, linear electric cylinder 105d. DETAILED DESCRIPTION
[0104] The present application will be further described in detail below with reference to the accompanying drawings and examples. It will be understood that the specific embodiments described herein are merely for explaining the related application and are not intended to limit the application. The described embodiments are merely a portion of the embodiments of the present application and are not intended to be exhaustive. All other embodiments derived by persons of ordinary skill in the art based on the embodiments in the present application without creative effort are intended to fall within the scope of protection of the present application.
[0105] Please refer to Figures 1 to 15. The sample sorting structure 100 in the embodiment of the present application uses a centrifugal and extrusion method to stratify and sort the sample bags to be sorted, thereby improving sorting efficiency and reducing labor costs.
[0106] As shown in FIG. 1 to FIG. 9 , the sample sorting structure 100 includes a centrifugal chamber assembly 101 , a rotary drive assembly 102 , a core shaft 103 , an extrusion platform 104 , and a horizontal push drive assembly 105 .
[0107] Centrifugal chamber assembly 101 includes a centrifugal inner cavity 101a, which provides space for sample bags to be sorted. For example, centrifugal inner cavity 101a is an annular inner cavity to achieve uniform sample stratification. Of course, centrifugal inner cavity 101a can also be configured in other shapes. The sample bags to be sorted are made of disposable plastic film and are inexpensive, suitable for holding samples such as blood.
[0108] The rotary drive assembly 102 drives the centrifugal chamber assembly 101 to rotate, thereby driving the sample bags to be sorted to perform centrifugal motion.
[0109] The core shaft 103 is connected to the centrifugal chamber assembly 101 for synchronous rotation. One end of the core shaft 103 extends into the centrifugal cavity 101a, as shown in Figures 3, 7, and 9, and is movable relative to the centrifugal cavity 101a. Specifically, the rotation axis of the core shaft 103 coincides with the rotation axis of the centrifugal cavity 101a, that is, the core shaft 103 and the centrifugal cavity 101a can rotate synchronously, and the core shaft 103 can also move along the rotation axis of the centrifugal cavity 101a.
[0110] The extrusion platform 104 is located within the centrifugal cavity 101a and is fixed to one end of the core shaft 103 extending into the centrifugal cavity 101a. Specifically, to facilitate assembly and disassembly of the extrusion platform 104 and the core shaft 103, a connecting disc 103b is provided on the core shaft 103. The connecting disc 103b has a through hole for connection to the extrusion platform 104 via fasteners. To facilitate positioning of the extrusion platform 104 and achieve coaxial arrangement of the extrusion platform 104 and the core shaft 103, a receiving groove 104b is provided on the extrusion platform 104 to accommodate the connecting disc 103b. As shown in FIG13 , the shape of the receiving groove 104b matches the shape of the connecting disc 103b.
[0111] In order to reduce the weight of the extrusion platform 104 , at least a section of the cross section of the extrusion platform 104 gradually decreases from the end away from the core shaft 103 to the end close to the core shaft 103 , as shown in FIG13 .
[0112] Of course, as shown in FIG14 , the extrusion platform 104 may also include a first turntable 104 c supporting the sample bag to be sorted and a second turntable 104 d connected to the core shaft 103 , wherein the second turntable 104 d is connected to the bottom end of the first turntable 104 c , and a reinforcing rib 104 e is provided between the first turntable 104 c and the second turntable 104 d .
[0113] The extrusion platform 104 is used to load the sample bags to be sorted and, driven by the core shaft 103, moves toward or away from the end of the centrifugal chamber 101a used to squeeze the sample bags to be sorted. To completely squeeze out the sample from the sample bags to be sorted, the loading end surface of the extrusion platform 104, which holds the sample bags to be sorted, can be arranged parallel to the extrusion end surface of the centrifugal chamber 101a used to squeeze the sample bags to be sorted. Specifically, the loading end surface and the extrusion end surface can both be flat, conical, or have other shapes. As long as the parallel arrangement is achieved, the shape falls within the scope of protection of this application.
[0114] The push drive assembly 105 drives the core shaft 103 to move in the centrifugal cavity 101a along the direction of the rotation axis of the centrifugal cavity 101a. The push drive assembly 105 is rotatably connected to the core shaft 103 to avoid affecting the rotation of the core shaft 103 when pushing the core shaft 103.
[0115] The present application adopts a centrifugal and extrusion method. Centrifugation can separate the samples and separate the target sample from the rest of the samples. The horizontal driving component 105 pushes the core shaft 103 horizontally to achieve complete fit between the extrusion platform 104 and the end face of the centrifugal cavity 101a used to squeeze the sample bag to be sorted, completely squeeze out the sample in the sample bag, and then completely collect the target sample, reducing the possibility of the loss of the target sample causing the detection and treatment to not meet the requirements.
[0116] In some embodiments, the centrifugal chamber assembly 101 includes a centrifugal chamber 101b, wherein the inner cavity of the centrifugal chamber 101b is the centrifugal inner cavity 101a. Specifically, as shown in FIG10 , the centrifugal chamber 101b includes a centrifugal chamber housing 101b-1 and a centrifugal chamber cover 101b-2. One end of the centrifugal chamber housing 101b-1 is open. For ease of description, the orientation shown in FIG2 is used, with the top end of the centrifugal chamber housing 101b-1 open, and the centrifugal chamber cover 101b-2 is disposed over the opening of the centrifugal chamber housing 101b-1. The end of the centrifugal chamber cover 101b-2 facing the centrifugal chamber housing 101b-1 is the extrusion end surface of the centrifugal inner cavity 101a for extruding the sample bag to be sorted.
[0117] In order to facilitate observation of the sorting status in the sample bag to be sorted in the centrifugal chamber 101b, at least a portion of the centrifugal chamber cover 101b-2 is made of transparent material, and the other portion can be made of aluminum, etc., which reduces the weight of the centrifugal chamber cover 101b-2 while ensuring strength.
[0118] To facilitate the removal and placement of sample bags to be sorted, the centrifuge chamber cover 101b-2 can be detachably connected to the centrifuge chamber housing 101b-1. Specifically, the centrifuge chamber cover 101b-2 can be detachably fixed to the centrifuge chamber housing 101b-1 using fasteners such as screws, or the centrifuge chamber cover 101b-2 can be hinged on one side to the centrifuge chamber housing 101b-1 and snap-fitted to the centrifuge chamber housing 101b-1 on the other side.
[0119] As shown in Figure 10, a rotation-limiting protrusion 101b-2a is provided on the edge of the centrifugal chamber cover 101b-2, and a rotation-limiting notch 101b-1a is provided at the top of the centrifugal chamber housing 101b-1 to limit the position of the rotation-limiting protrusion 101b-2a, so as to achieve a stable connection between the centrifugal chamber cover 101b-2 and the centrifugal chamber housing 101b-1. Specifically, there are multiple rotation-limiting protrusions 101b-2a, which are evenly distributed in an annular manner around the circumference of the centrifugal chamber cover 101b-2. Correspondingly, the top of the centrifugal chamber housing 101b-1 is evenly distributed in an annular manner with multiple rotation-limiting notches 101b-1a, and the rotation-limiting notches 101b-1a are arranged in a one-to-one correspondence with the rotation-limiting protrusions 101b-2a.
[0120] To facilitate the connection between the centrifuge chamber cover and the centrifuge chamber housing, a connecting post 101b-2b is provided on either the centrifuge chamber cover 101b-2 or the centrifuge chamber housing 101b-1, with a fastening hole provided on the end surface of the connecting post 101b-2b facing the other, and the other is detachably connected to the connecting post 101b-2b via a fastener. A through hole 104a is provided on the extrusion platform 104 to allow the connecting post 101b-2b to pass through, as shown in Figure 12. For example, the connecting post 101b-2b is installed on the centrifuge chamber cover 101b-2, as shown in Figure 11.
[0121] In order to facilitate the sample bag to be sorted to rotate together with the centrifugal chamber 101b, a limiting through hole is opened on the sample bag to be sorted to allow the connecting column 101b-2b to pass through. The connecting column 101b-2b passes through the limiting through hole on the sample bag to be sorted, so that the sample bag to be sorted can rotate together with the centrifugal chamber 101b.
[0122] It should be noted that the connecting column 101b-2b may not be provided. Specifically, the centrifugal chamber cover 101b-2 and the centrifugal chamber shell 101b-1 are respectively provided with connecting holes, and the two are detachably connected by fasteners such as bolts. The extrusion platform 104 is provided with a through hole 104a for allowing the fastener to pass through, and the fastener can also pass through the limiting through hole on the sample bag to be sorted.
[0123] In some embodiments, in order to facilitate the output of samples in the sample bag to be sorted, the centrifugal chamber 101b also includes a rotary joint 101d, as shown in Figures 7 and 9. The rotary joint 101d is installed on the centrifugal chamber cover 101b-2, one end of which is connected to the outlet of the sample bag to be sorted, and the other end is used for an external output pipeline.
[0124] As shown in Figures 7 and 9, the centrifugal chamber assembly 101 also includes a joint fixing piece 101e and a centrifugal rubber block 101f. The centrifugal rubber block 101f is inserted into the rubber block fixing through hole provided on the centrifugal chamber cover 101b-2, and the centrifugal rubber block 101f is provided with a mounting hole for installing one end of the rotary joint 101d. The centrifugal rubber block 101f is convenient for achieving a sealed connection with the centrifugal chamber cover 101b-2. Specifically, the centrifugal rubber block 101f is coaxially arranged with the centrifugal chamber 101b.
[0125] The sample bag to be sorted in the centrifugal chamber 101b is connected to the rotary joint 101d to output the sample in the sample bag to be sorted.
[0126] The joint fixing part 101e is fixed, and the other end of the rotary joint 101d is installed on the joint fixing part 101e and extends out of the joint fixing part 101e to be connected to the external output pipeline.
[0127] As shown in Figures 6-9, centrifugal chamber assembly 101 also includes a protective cover 101g. Protective cover 101g is stationary and positioned above centrifugal chamber 101b to prevent users from accidentally touching the rotating centrifugal chamber 101b. A connector fixture 101e is mounted on top of protective cover 101g to secure it in place. When the sample sorting structure is used in sorting apparatus 1000, as shown in Figure 16, protective cover 101g is mounted on base frame 200.
[0128] Furthermore, the protective cover 101g is made of a transparent material, which facilitates observation of the situation inside the centrifugal chamber 101b.
[0129] In order to facilitate the taking and placing of the protective cover 101g, a handle 101g-1 is provided on the top of the protective cover 101g.
[0130] To facilitate the connection between centrifugal chamber assembly 101 and core shaft 103, centrifugal chamber assembly 101 further includes a sleeve 101c, which is mounted on centrifugal chamber 101b. Specifically, a through hole for accommodating sleeve 101c is defined at the bottom end of centrifugal chamber housing 101b-1, into which the top end of sleeve 101c is inserted. A limiting step 101c-1 is provided near the top end of sleeve 101c, with the top end of limiting step 101c-1 abutting against the bottom end of centrifugal chamber housing 101b-1.
[0131] The rotary drive assembly 102 is in transmission connection with the sleeve 101c, the core shaft 103 is sleeved in the sleeve 101c, and the top end extends out of the sleeve 101c and enters the centrifugal cavity 101a, and the bottom end extends out of the sleeve 101c and is in transmission connection with the push drive assembly 105.
[0132] As shown in Figure 15, the outer wall of the core shaft 103 is provided with a spline 103a, and the inner wall of the sleeve 101c is provided with a spline 103a that cooperates with the spline 103a of the core shaft 103. Of course, a key bar can also be provided instead of the spline 103a. As long as the transmission method can achieve both torque transmission and sliding movement of the core shaft 103 relative to the sleeve 101c, it falls within the scope of protection of this application.
[0133] In some embodiments, the rotary drive assembly 102 includes a first mounting seat 102a, a bearing seat 102b, a bearing assembly 102c, a first driver 102d, and a first transmission mechanism 102e.
[0134] The first mounting base 102a is fixed and can be installed on a base frame of a desired system, or directly fixed on the ground.
[0135] The first mounting seat 102a is provided with a mounting hole for allowing the shaft sleeve 101c to pass through, and there is a certain gap between the outer wall of the shaft sleeve 101c and the inner wall of the mounting hole.
[0136] The bearing seat 102b is mounted on the first mounting seat 102a. Specifically, the bearing seat 102b is detachably mounted on the top of the first mounting seat 102a by fasteners such as bolts.
[0137] The bearing group 102c is installed in the bearing seat 102b. As shown in Figures 3 and 4, the bearing group 102c includes a first bearing 102c-1 and a second bearing 102c-2, which are respectively installed at the two ends of the inner cavity of the bearing seat 102b. For example, the number of first bearing 102c-1 is 1 and the number of second bearings 102c-2 is 2, that is, the second bearings 102c-2 are angular contact ball bearings installed in pairs.
[0138] The rotary drive assembly 102 further includes a first spacer 102f, a second spacer 102g, and a locking member 102h.
[0139] The end of the inner ring of the first bearing 102c-1 facing the centrifugal chamber 101b abuts against the bottom end of the first limiting step 101c-1, and the first spacer 102f is sleeved outside the shaft sleeve 101c, and the end facing the centrifugal chamber 101b abuts against the end of the inner ring of the first bearing 102c-1 away from the centrifugal chamber 101b.
[0140] A limiting protrusion 102b-1 is provided on the inner wall of the bearing seat 102b, and an end of the outer ring of the first bearing 102c-1 facing away from the centrifugal chamber 101b abuts against an end of the limiting protrusion 102b-1 facing the centrifugal chamber 101b.
[0141] The inner end of the second bearing 102c-2, facing the centrifugal chamber 101b, abuts against the end of the first spacer 102f, facing away from the centrifugal chamber 101b. The outer end of the second bearing 102c-2, facing the centrifugal chamber 101b, abuts against the end of the limiting protrusion 102b-1, facing away from the centrifugal chamber 101b. It should be noted that the length of the first spacer 102f is equal to the length of the limiting protrusion 102b-1.
[0142] The second spacer 102g is sleeved on the outside of the shaft sleeve 101c, and its end facing the centrifugal chamber 101b abuts against the end of the inner ring of the second bearing 102c-2 away from the centrifugal chamber 101b. The locking piece 102h is locked on the outside of the shaft sleeve 101c, and its end facing the centrifugal chamber 101b abuts against the end of the second spacer 102g away from the centrifugal chamber 101b.
[0143] That is to say, the bearing seat 102b cooperates with the shaft sleeve 101c, the first spacer sleeve 102f and the second spacer sleeve 102g to limit and fix the bearing group 102c, thereby facilitating the stable operation of the centrifuge.
[0144] It should be noted that the locking member 102h can be any structure that can achieve locking of the second spacer 102g, and the locking member 102h is taken as a locking nut as an example.
[0145] The first driver 102d is mounted on the first mounting seat 102a and is in transmission connection with the shaft sleeve 101c via the first transmission mechanism 102e.
[0146] Specifically, the first driver 102d is a first motor, which directly provides power to the first transmission mechanism 102e. Of course, the first driver 102d can also include a first motor and a first reducer connected to the first motor, and the power provided by the first motor is reduced by the first reducer before being transmitted to the first transmission mechanism 102e.
[0147] Furthermore, the present application discloses that the first transmission mechanism 102e is a transmission belt mechanism, which includes a driving pulley 101e-1, a driven pulley 101e-2, and a transmission belt 101e-3. Taking the first driver 102d as a first motor as an example, the driving pulley 101e-1 is mounted on the output shaft of the first motor, the driven pulley 101e-2 is mounted outside the shaft sleeve 101c, and the transmission belt 101e-3 is respectively connected to the driving pulley 101e-1 and the driven pulley 101e-1. Specifically, the shaft sleeve 101c is provided with a shoulder at the top end of the driven pulley 101e-2, and the bottom end of the driven pulley 101e-2 is locked to the shaft sleeve 101c via a nut.
[0148] It should be noted that the first transmission mechanism 102e may also be set as other mechanisms, such as a transmission gear mechanism or a transmission chain mechanism, etc., through gear transmission or chain transmission.
[0149] As shown in FIG. 2 , the first transmission mechanism 102 e and the bearing seat 102 b are respectively installed at two ends of the first mounting seat 102 a .
[0150] In some embodiments, the horizontal push drive assembly 105 includes a second mounting base 105a, a second driver 105b, and a second transmission mechanism 105c.
[0151] The second mounting base 105a is fixed and can be installed on a base of a system to be used, or directly fixed on the ground.
[0152] The second driver 105b is installed on the second mounting seat 105a. Specifically, the second driver 105b includes a second motor 105b-1, a transmission shaft 105b-2 and a fourth bearing 105b-3. The second motor 105b-1 is installed on the second mounting seat 105a and is connected to the transmission shaft 105b-2. The transmission shaft 105b-2 is rotatably mounted on the second mounting seat 105a through the fourth bearing 105b-3 with a seat.
[0153] In order to adjust the rotational speed output by the second motor 105b-1, a second reducer 105b-5 may be provided between the second motor 105b-1 and the transmission shaft 105b-2.
[0154] One end of the second transmission mechanism 105c is transmission-connected to the transmission shaft 105b-2, and the other end is transmission-connected to the end of the core shaft 103 away from the centrifugal chamber assembly 101, and is used to drive the core shaft 103 to move in the centrifugal cavity 101a under the drive of the second driver 105b.
[0155] It should be noted that the specific structure of the horizontal push drive assembly 105 disclosed above is only a specific implementation method of the present application. In actual applications, the horizontal push drive assembly 105 can also be set to include a second mounting seat 105a and a linear electric cylinder, air cylinder, hydraulic cylinder or electric push rod installed on the second mounting seat 105a, and the core shaft 103 is rotatably connected to the driving end of the linear electric cylinder, air cylinder, hydraulic cylinder or electric push rod.
[0156] In some embodiments, as shown in Figures 8 and 9, taking the push drive assembly 105 including the second mounting base 105a and the linear electric cylinder 105d mounted on the second mounting base 105a as an example, the linear electric cylinder 105d is driven by a motor and a reducer to drive a ball screw, thereby pushing the extension shaft of the linear electric cylinder 105d to move axially, and due to the structural guidance of the extension shaft itself, it can only move axially and cannot rotate.
[0157] As shown in Figures 2 and 3, the second transmission mechanism 105c is a rocker sliding mechanism, which includes a rocker arm 105c-1, a connecting rod 105c-2, a bearing chamber 105c-3 and a third bearing 105c-4. One end of the rocker arm 105c-1 is fixed on the transmission shaft 105b-2 to achieve transmission connection with the second driver 105b.
[0158] The other end of rocker arm 105c-1 is hingedly connected to one end of connecting rod 105c-2, the other end of connecting rod 105c-2 being hingedly connected to bearing chamber 105c-3. A third bearing 105c-4 is mounted within bearing chamber 105c-3, and the end of spindle 103 facing away from centrifugal chamber assembly 101 is rotatably connected to third bearing 105c-4. The rotation axis of rocker arm 105c-1 is perpendicular to the direction of movement of spindle 103 within centrifugal chamber 101a, as shown in Figure 3.
[0159] Specifically, as shown in FIG5 , a first limiting boss 105c-3a is provided at a position near the bottom end of the inner wall of the bearing chamber 105c-3, the outer ring of the third bearing 105c-4 is sleeved in the bearing chamber 105c-3, and the bottom end of the outer ring of the third bearing 105c-4 abuts against the first limiting boss 105c-3a; the inner ring of the third bearing 105c-4 is sleeved outside the core shaft 103, and the bottom end of the inner ring of the third bearing 105c-4 abuts against the nut installed at the bottom end of the core shaft 103; the core shaft 103 is provided with A second limiting boss 103d abuts against the top of the inner ring of the third bearing 105c-4; the top cover of the bearing chamber 105c-3 is provided with a bearing chamber cover 105c-3b, and the bearing chamber cover 105c-3b is provided with an avoidance hole allowing the core shaft 103 to pass through, and the end of the bearing chamber cover 105c-3b facing the bearing chamber 105c-3 is provided with a limiting ring 105c-3b-1 extending from the inner cavity of the bearing chamber 105c-3, and the limiting ring 105c-3b-1 abuts against the top of the outer ring of the third bearing 105c-4.
[0160] It should be noted that the second transmission mechanism 105c being a rocker sliding mechanism is only a specific embodiment of the present application. In actual applications, the second transmission mechanism 105c can also be set as a screw and nut mechanism, and the core shaft 103 is rotatably connected to the nut of the screw and nut mechanism.
[0161] In order to facilitate the adjustment of the connection length between the rocker arm 105c-1 and the bearing chamber 105c-3, the rocker sliding mechanism further includes a first joint bearing 105c-5 and a second joint bearing 105c-6.
[0162] One end of the first spherical plain bearing 105c-5 is threadedly connected to one end of the connecting rod 105c-2, and the other end is hingedly connected to the third bearing 105c-4 seat 102b. One end of the second spherical plain bearing 105c-6 is threadedly connected to the other end of the connecting rod 105c-2, and the other end is hingedly connected to the rocker arm 105c-1. Specifically, one of the first spherical plain bearing 105c-5 and the second spherical plain bearing 105c-6 is a positive thread spherical plain bearing, and the other is a negative thread spherical plain bearing.
[0163] To prevent the core shaft 103 from colliding with the centrifugal chamber 101a due to excessive displacement within the centrifugal chamber 101a, the horizontal push drive assembly 105 further includes a limit sensor 105b-4 mounted on the second mounting base 105a and configured to detect the rotation angle of the transmission shaft 105b-2. Specifically, the limit sensor 105b-4 may comprise a plurality of photoelectric sensors that mark the rotation angle of the transmission shaft 105b-2, or an encoder that provides feedback on the rotation angle of the transmission shaft 105b-2.
[0164] In order to further control the displacement of the core shaft 103, the present application discloses that a detection groove 103c is opened on the core shaft 103, and an in-place sensor is installed at the bottom end of the sleeve 101c. The detection groove 103c is located above the in-place sensor. When the detection groove 103c moves to a position flush with the in-place sensor, the in-place sensor is connected to an alarm to sound an alarm.
[0165] In a second aspect, as shown in FIG16 , the present application provides a sorting device 1000 . Specifically, the sorting device 1000 includes a base frame 200 , a control device 300 , and a sample sorting structure 100 as in any one of the above embodiments.
[0166] The sample sorting structure 100 and the control device 300 are both installed on the base frame 200 , and the control device 300 is connected to the sample sorting structure 100 via signals to control the operation of the sample sorting structure 100 .
[0167] Specifically, as shown in Figure 10, the control device 300 specifically includes a controller and a touch screen connected to the controller signal. The controller controls the operation of various parts of the sorting equipment 1000. The touch screen can display the operating status of various parts of the sorting equipment 1000 in a timely manner, and can also facilitate interaction with people.
[0168] In order to facilitate the installation of various parts of the sorting equipment 1000, the present application discloses a base frame 200 including a frame body 201 and an installation panel 202 installed on the top of the frame body 201. The installation panel 202 is specifically arranged on one side of the top of the frame body 201 for installing pipelines, etc. The frame body 201 is used to install the sample sorting structure 100.
[0169] In a third aspect, the present application provides a sample sorting method, comprising:
[0170] Providing a sample sorting structure 100 as described above;
[0171] Place the sample bag to be sorted on the extrusion platform 104 of the centrifugal chamber 101a;
[0172] Start the rotary drive assembly 102 to drive the centrifugal chamber assembly 101 and the core shaft 103 to rotate synchronously, thereby driving the sample bag to be sorted to rotate and perform sample stratification;
[0173] The horizontal driving assembly 105 is started to drive the core shaft 103 to move along the end close to the centrifugal cavity 101a for squeezing the sample bag to be sorted, thereby squeezing the sample bag to be sorted and squeezing the stratified samples in the sample bag to be sorted into the corresponding device to be contained.
[0174] The present invention realizes the separation of samples by squeezing different sample layers in a sample bag to be sorted into corresponding containers. The present invention adopts an automatic sorting method, which improves the efficiency of sample sorting and reduces labor costs.
[0175] In a fourth aspect, the present application provides a sample sorting fluid system, comprising an output pipeline, a sorting holding device, and a sample sorting structure 100 as any one of the above.
[0176] The outlet of the sample bag to be sorted in the sample sorting structure 100 is connected to the inlet of the output pipeline through a rotary joint, and each outlet of the output pipeline is respectively connected to the corresponding sorting containing device.
[0177] Since the sample sorting fluid system provided in the present application includes the sample sorting structure 100 in any one of the above embodiments, the beneficial effects of the sample sorting structure 100 are all included in the sample sorting fluid system provided in the present application.
[0178] In a fifth aspect, the present application provides a sample culture system, comprising an output pipeline, a sample culture vessel, and a sample sorting structure 100 as in any one of the above embodiments.
[0179] The outlet of the sample bag to be sorted in the sample sorting structure 100 is connected to the inlet of the output pipeline through a rotary joint, and each outlet of the output pipeline is connected to a corresponding sample culture vessel.
[0180] Since the sample culture system provided in the present application includes the sample sorting structure 100 in any one of the above embodiments, the beneficial effects of the sample sorting structure 100 are all included in the sample culture system provided in the present application.
[0181] It should be noted that, for ease of description, only the parts related to the relevant applications are shown in the drawings. In the absence of conflict, the embodiments and features in the embodiments of this application can be combined with each other.
[0182] It should be understood that the terms "system," "device," "unit," and / or "module" used in this application are a method for distinguishing different components, elements, parts, portions, or assemblies at different levels. However, if other terms can achieve the same purpose, the terms may be replaced by other expressions.
[0183] As used in this application and the claims, unless the context clearly indicates an exception, the terms "a," "an," "an," and / or "the" are not intended to refer to the singular and may include the plural, unless the context clearly indicates otherwise. Generally speaking, the terms "comprises" and "include" only indicate the inclusion of the steps and elements specifically identified, and these steps and elements do not constitute an exclusive list. A method or apparatus may also include other steps or elements. The phrase "comprises a..." does not preclude the presence of additional identical elements in the process, method, product, or apparatus that includes the elements.
[0184] In the description of the embodiments of this application, unless otherwise specified, " / " represents or. For example, A / B can represent A or B. "And / or" in this article is simply a description of the association relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A exists alone, A and B exist at the same time, and B exists alone. In addition, in the description of the embodiments of this application, "plurality" means two or more than two.
[0185] In the following, the terms "first" and "second" are used for descriptive purposes only and should not be understood to indicate or imply relative importance or implicitly specify the quantity of the technical features indicated. Therefore, a feature specified as "first" or "second" may explicitly or implicitly include one or more of the features.
[0186] Flowcharts are used in this application to illustrate the operations performed by the systems according to the embodiments of the present application. It should be understood that the preceding or following operations are not necessarily performed in exact order. Instead, the steps may be processed in reverse order or simultaneously. Furthermore, other operations may be added to these processes, or one or more operations may be removed from these processes.
[0187] The above description is only a preferred embodiment of the present application and an explanation of the technical principles used, and is not intended to limit the present application. For those skilled in the art, the present application may have various changes and variations. The scope of application involved in this application is not limited to the technical solutions formed by a specific combination of the above-mentioned technical features, but should also cover other technical solutions formed by any combination of the above-mentioned technical features or their equivalent features without departing from the above-mentioned application concept. For example, the above-mentioned features are replaced with (but not limited to) technical features with similar functions disclosed in this application to form a technical solution.
Claims
1. A sample sorting structure (100), characterized in that: include: A centrifugal chamber assembly (101), wherein the centrifugal chamber assembly (101) has a centrifugal inner cavity (101a); a rotary drive assembly (102) for driving the centrifugal chamber assembly (101) to rotate; a core shaft (103), the core shaft (103) being connected to the centrifugal chamber assembly (101) for synchronous rotation, one end of the core shaft (103) extending to the centrifugal inner cavity (101a) and being movable relative to the centrifugal inner cavity (101a); an extrusion platform (104) fixed to one end of the core shaft (103) extending to the centrifugal inner chamber (101a), the extrusion platform (104) being used to load the sample bag to be sorted and moving toward or away from the end of the centrifugal inner chamber (101a) for squeezing the sample bag to be sorted under the drive of the core shaft (103); A horizontal push drive assembly (105) drives the core shaft (103) to move in the centrifugal inner chamber (101a), and the horizontal push drive assembly (105) is rotatably connected to the core shaft (103).
2. The sample sorting structure (100) according to claim 1, characterized in that: One end of the centrifugal cavity (101a) used for squeezing the sample bag to be sorted is arranged in parallel with one end of the squeezing platform (104) used for loading the sample bag to be sorted.
3. The sample sorting structure (100) according to claim 2, characterized in that: The centrifugal chamber assembly (101) comprises: A centrifugal chamber (101b), wherein the inner cavity of the centrifugal chamber (101b) is the centrifugal inner cavity (101a); A shaft sleeve (101c) is mounted on the centrifugal chamber (101b), the rotary drive assembly (102) is in transmission connection with the shaft sleeve (101c), the core shaft (103) is sleeved in the shaft sleeve (101c), and one end of the core shaft extends out of the shaft sleeve (101c) and enters the centrifugal inner cavity (101a), and the other end extends out of the shaft sleeve (101c) and is in transmission connection with the horizontal push drive assembly (105).
4. The sample sorting structure (100) according to claim 3, characterized in that: The shaft sleeve (101c) is connected to the core shaft (103) via a spline (103a) or a key bar.
5. The sample sorting structure (100) according to claim 3, characterized in that: The centrifugal chamber (101b) comprises a centrifugal chamber shell (101b-1) and a centrifugal chamber cover (101b-2); One end of the centrifugal chamber housing (101b-1) is open, and the centrifugal chamber cover (101b-2) is detachably provided at the opening of the centrifugal chamber housing (101b-1); The shaft sleeve (101c) is fixed to an end of the centrifugal chamber housing (101b-1) away from the opening.
6. The sample sorting structure (100) according to claim 5, characterized in that: A rotation-limiting protrusion (101b-2a) is provided on the edge of the centrifugal chamber cover (101b-2), and a rotation-limiting notch (101b-1a) for limiting the position of the rotation-limiting protrusion (101b-2a) is provided at the top of the centrifugal chamber housing (101b-1); and / or A connecting column (101b-2b) is provided on either of the surfaces of the centrifugal chamber cover (101b-2) and the centrifugal chamber housing (101b-1) facing each other, a fastening hole is provided on the end surface of the connecting column (101b-2b) facing the other, and the other is detachably connected to the connecting column (101b-2b) via a fastener, and a through hole (104a) is provided on the extrusion platform (104) to allow the connecting column (101b-2b) to pass through; or The centrifugal chamber cover (101b-2) and the centrifugal chamber housing (101b-1) are respectively provided with communication holes, and the two are detachably connected via fasteners. The extrusion platform (104) is provided with a through hole (104a) allowing the fasteners to pass through.
7. The sample sorting structure (100) according to claim 5, characterized in that: The centrifugal chamber assembly (101) further comprises a rotary joint (101d), which is mounted on the centrifugal chamber cover (101b-2), one end of which is connected to the outlet of the sample bag to be sorted, and the other end of which is used for connecting to an external output pipeline.
8. The sample sorting structure (100) according to claim 7, characterized in that: The centrifugal chamber assembly (101) further comprises a joint fixing member (101e) and a centrifugal rubber block (101f); The centrifugal rubber block (101f) is inserted into a rubber block fixing through hole provided on the centrifugal chamber cover (101b-2), and a mounting hole for mounting one end of the rotary joint (101d) is provided on the centrifugal rubber block (101f), and the sample bag to be sorted in the centrifugal chamber (101b) is communicated with the rotary joint (101d); The joint fixing part (101e) is fixed, and the other end of the rotary joint (101d) is mounted on the joint fixing part (101e) and extends out of the joint fixing part (101e) to be externally connected to the output pipeline.
9. The sample sorting structure (100) according to claim 5, characterized in that: The centrifugal chamber assembly (101) further includes a protective cover (101g); The protective cover (101g) is fixed and located above the centrifugal chamber (101b); The joint fixing member (101e) is installed on the top end of the protective cover (101g).
10. The sample sorting structure (100) according to claim 5, characterized in that: The protective cover (101g) is made of a transparent material; and / or A handle (101g-1) is provided at the top of the protective cover (101g).
11. The sample sorting structure (100) according to claim 1, characterized in that: The extrusion platform (104) has at least one section of cross-section that gradually decreases from one end away from the core shaft (103) to one end close to the core shaft (103); or The extrusion platform (104) includes a first turntable (104c) supporting the sample bag to be sorted and a second turntable (104d) connected to the core shaft (103), the second turntable (104d) is connected to the bottom end of the first turntable (104c), and a reinforcing rib (104e) is provided between the first turntable (104c) and the second turntable (104d); and / or The core shaft (103) is provided with a connecting disk (103b) connected to the extrusion platform (104).
12. The sample sorting structure (100) according to claim 3, characterized in that: The rotary drive assembly (102) includes: a first mounting seat (102a), wherein the first mounting seat (102a) is provided with a mounting hole allowing the shaft sleeve (101c) to pass through; A bearing seat (102b) mounted on the first mounting seat (102a); A bearing group (102c) is installed in the bearing seat (102b), and the shaft sleeve (101c) is sleeved in the bearing group (102c); a first driver (102d) mounted on the first mounting seat (102a); A first transmission mechanism (102e) is respectively connected to the first driver (102d) and the shaft sleeve (101c).
13. The sample sorting structure (100) according to claim 9, characterized in that: The first driver (102d) is a first motor, or the first driver (102d) includes a first motor and a first reducer connected to the first motor; and / or The first transmission mechanism (102e) is a transmission belt mechanism, a transmission gear mechanism or a transmission chain mechanism; and / or The first transmission mechanism (102e) and the bearing seat (102b) are respectively mounted on two ends of the first mounting seat (102a).
14. The sample sorting structure (100) according to claim 13, characterized in that: The rotary drive assembly (102) further includes a first spacer (102f), a second spacer (102g) and a locking member (102h); The bearing group (102c) includes a first bearing (102c-1) and a second bearing (102c-2); The outer wall of the shaft sleeve (101c) is provided with a first limiting step (101c-1); one end of the inner ring of the first bearing (102c-1) facing the centrifugal chamber (101b) abuts against the first limiting step (101c-1); the first spacer (102f) is sleeved outside the shaft sleeve (101c), and one end of the first spacer (102f) facing the centrifugal chamber (101b) abuts against one end of the inner ring of the first bearing (102c-1) facing away from the centrifugal chamber (101b); A limiting protrusion (102b-1) is provided on the inner wall of the bearing seat (102b), and one end of the outer ring of the first bearing (102c-1) facing away from the centrifugal chamber (101b) abuts against one end of the limiting protrusion (102b-1) facing the centrifugal chamber (101b); One end of the inner ring of the second bearing (102c-2) facing the centrifugal chamber (101b) abuts against one end of the first spacer (102f) facing away from the centrifugal chamber (101b); one end of the outer ring of the second bearing (102c-2) facing the centrifugal chamber (101b) abuts against one end of the limiting protrusion facing away from the centrifugal chamber (101b); the second spacer (102g) is sleeved outside the shaft sleeve (101c), and one end facing the centrifugal chamber (101b) abuts against one end of the inner ring of the second bearing (102c-2) facing away from the centrifugal chamber (101b); the locking member (102h) is locked outside the shaft sleeve (101c), and one end facing the centrifugal chamber (101b) abuts against one end of the second spacer (102g) facing away from the centrifugal chamber (101b).
15. The sample sorting structure (100) according to any one of claims 1 to 14, characterized in that: The horizontal push drive assembly (105) comprises: a second mounting seat (105a); a second driver (105b) mounted on the second mounting seat (105a); and a second transmission mechanism (105c), wherein one end of the second transmission mechanism (105c) is transmission-connected to the second driver (105b), and the other end of the second transmission mechanism (105c) is transmission-connected to an end of the core shaft (103) away from the centrifugal chamber assembly (101), and is used for driving the core shaft (103) to move in the centrifugal inner cavity (101a) under the drive of the second driver (105b); or The horizontal push drive assembly (105) includes: a second mounting seat (105a); a linear electric cylinder (105d), an air cylinder, a hydraulic cylinder or an electric push rod mounted on the second mounting seat (105a); and the core shaft (103) is rotatably connected to the driving end of the linear electric cylinder (105d), the air cylinder, the hydraulic cylinder or the electric push rod.
16. The sample sorting structure (100) according to claim 15, characterized in that: The second transmission mechanism (105c) is a rocker sliding mechanism, which includes a rocker arm (105c-1), a connecting rod (105c-2), a bearing chamber (105c-3) and a third bearing (105c-4). One end of the rocker arm (105c-1) is in transmission connection with the second driver (105b), the other end of the rocker arm (105c-1) is hinged to one end of the connecting rod (105c-2), the other end of the connecting rod (105c-2) is hinged to the bearing chamber (105c-3), the third bearing (105c-4) is installed in the bearing chamber (105c-3), and the end of the core shaft (103) away from the centrifugal chamber assembly (101) is rotatably connected to the third bearing (105c-4). The rotation axis of the rocker arm (105c-1) is perpendicular to the direction in which the core shaft (103) moves in the centrifugal cavity (101a); or The second transmission mechanism (105c) is a screw-nut mechanism, and the core shaft (103) is rotatably connected to the nut of the screw-nut mechanism.
17. The sample sorting structure (100) according to claim 16, characterized in that: The rocker sliding mechanism further includes a first joint bearing (105c-5) and a second joint bearing (105c-6); One end of the first joint bearing (105c-5) is threadedly connected to one end of the connecting rod (105c-2), and the other end is hinged to the second bearing seat (102b); One end of the second joint bearing (105c-6) is threadedly connected to the other end of the connecting rod (105c-2), and the other end is hinged to the rocker arm (105c-1).
18. The sample sorting structure (100) according to claim 16, characterized in that: The second driver (105b) includes a second motor (105b-1), a transmission shaft (105b-2) and a fourth bearing (105b-3); The second motor (105b-1) is mounted on the second mounting seat (105a) and is in transmission connection with the transmission shaft (105b-2); the transmission shaft (105b-2) is rotatably mounted on the second mounting seat (105a) via the fourth bearing (105b-3); and the rocker arm (105c-1) is fixed on the transmission shaft (105b-2).
19. The sample sorting structure (100) according to claim 18, characterized in that: The horizontal push drive assembly (105) further includes a limit sensor (105b-4); The limit sensor (105b-4) is mounted on the second mounting seat (105a) and is used to detect the rotation angle of the transmission shaft (105b-2).
20. A sorting device (1000), characterized in that: It comprises a base frame (200), a control device (300) and a sample sorting structure (100) according to any one of claims 1 to 19; The sample sorting structure (100) and the control device (300) are both installed on the base frame (200), and the control device (300) is connected to the sample sorting structure (100) by signal.
21. A sample sorting fluid system, characterized in that: It comprises an output pipeline, a sorting and holding device, and the sample sorting structure (100) according to any one of claims 1 to 19 or the sorting device (1000) according to claim 20; The outlet of the sample bag to be sorted in the sample sorting structure (100) is connected to the inlet of the output pipeline through a rotary joint, and each outlet of the output pipeline is respectively connected to the corresponding sorting containing device.
22. A sample culture system, characterized in that: comprising an output pipeline, a sample culture vessel, and a sample sorting structure (100) as claimed in any one of claims 1 to 19; The outlet of the sample bag to be sorted in the sample sorting structure (100) is connected to the inlet of the output pipeline through a rotary joint, and each outlet of the output pipeline is respectively connected to the corresponding sample culture vessel.
23. A sample sorting method, characterized in that: include: Providing a sample sorting structure (100) according to any one of claims 1 to 19; Placing a sample bag to be sorted on the squeezing platform (104) of the centrifugal chamber (101a); Starting the rotary drive assembly to drive the centrifugal chamber assembly (101) and the core shaft (103) to rotate synchronously, thereby driving the sample bag to be sorted to rotate and perform sample stratification; The horizontal push drive assembly (105) is started to drive the core shaft (103) to move along one end close to the centrifugal inner cavity (101a) for squeezing the sample bag to be sorted, thereby squeezing the sample bag to be sorted and squeezing the layered samples in the sample bag to be sorted into the corresponding device to be contained.