Minimally invasive intervertebral disc positioning device

Abstract

The invention discloses a minimally invasive intervertebral disc positioning device, which comprises an outer sleeve, an inner sleeve and a positioning device, the inner sleeve is nested in the first inner cavity in a sliding mode, and the inner sleeve is provided with a second inner cavity extending in the axial direction; the clamping piece extends into the second inner cavity from the top end of the outer sleeve and is coaxially nested in the second inner cavity in a sliding manner; the clamping piece is used for fixing a puncture needle and enabling the tip end of the puncture needle to extend out of the bottom end of the inner sleeve; and the first elastic body surrounds the clamping piece between the top end of the inner sleeve and the top wall of the first inner cavity. Through the retraction length of the inner sleeve relative to the outer sleeve and the elastic deformation condition of the first elastic body, the purpose of accurately positioning the intervertebral disc on the X-axis and the Y-axis can be achieved without imaging assistance, an experimenter does not need to be exposed in imaging-assisted X-rays to be hurt, expensive X-ray perspective equipment does not need to be purchased, and the experiment cost is reduced. The cost and threshold are reduced.

Description

Technical Field

[0001] The present invention relates to the field of medical technology, and particularly to a minimally invasive intervertebral disc positioning device. Background Art

[0002] Low back pain is a common disorder that affects people's daily lives globally, and its incidence has gradually increased in recent years, imposing a huge medical burden on the global medical system. The main cause of low back pain is lumbar intervertebral disc degeneration. The main method for studying intervertebral disc degeneration is to construct an animal intervertebral disc degeneration model to study the disease progression and degeneration mechanism of intervertebral disc degeneration.

[0003] Currently, the constructed animal intervertebral disc degeneration models can be divided into mechanical stress change models, nucleus pulposus annulus fibrosus injury models, endplate injury and nutritional disorder models, chemical induction models, and genetic-related models. Among them, the method of creating a model by puncturing the intervertebral disc with a needle in the nucleus pulposus annulus fibrosus injury model is one of the most common and effective modeling methods. However, in the existing literature or technologies, the modeling and injection drug administration methods of the acupuncture model are diverse. Some can easily locate the position of the intervertebral disc with the help of X-rays, complete puncture and injection drug administration, but the disadvantage is that the experimenter will be exposed to a certain dose of X-rays, which will cause harm to the experimenter. Some locate the intervertebral disc under direct vision by incising the skin and separating the nearby connective tissue, and then perform puncture and injection drug administration. However, the disadvantage is that the surgical process is relatively cumbersome, causing great damage to the animal, and the open surgery brings more confounding factors to the animal model, which also has a great relationship with the level of the operator. Some achieve minimally invasive surgery through percutaneous channel puncture modeling, but its disadvantage is that the intervertebral disc cannot be located under direct vision, and it is still difficult to accurately locate the intervertebral disc without X-rays. In addition, there are also many improved surgical procedures and processes, such as bending the needle tip and installing a limiter to limit the needle insertion depth. This effectively achieves accurate positioning on the Z-axis, but it does not solve the problem of how to accurately locate the intervertebral disc on the XY-axis without imaging assistance. Instead, due to these diverse modeling methods, the experiment is complicated, the uncertainty of the experiment is increased, and the experimental repeatability is poor.

[0004] In terms of intervertebral disc injection drug administration, because it also requires accurate positioning of the intervertebral disc to complete drug administration, the above-mentioned deficiencies in intervertebral disc positioning also affect the process of intervertebral disc injection drug administration. Especially for some drug studies that require multiple intervertebral disc injection drug administrations, whether it is multiple positioning with the help of X-rays or multiple direct vision positioning through open surgery, the impact brought by the above-mentioned deficiencies will be amplified.

[0005] Furthermore, the cost of training the operator's ability by practicing intervertebral disc positioning through these surgical procedures is high, and it is difficult for beginners to get started. Summary of the Invention

[0006] The present invention provides a minimally invasive intervertebral disc positioning device, which is used to solve the problem in the prior art that it is necessary to accurately position the intervertebral disc on the XY axis with the aid of imaging, resulting in harm to the experimenter in X-rays.

[0007] The technical solution of the present invention is a minimally invasive intervertebral disc positioning device, including:

[0008] An outer sleeve, the outer sleeve having a first inner cavity extending axially;

[0009] An inner sleeve, the inner sleeve being slidably nested in the first inner cavity, the inner sleeve having a second inner cavity extending axially;

[0010] A clamping member, the clamping member extending from the top end of the outer sleeve and being slidably coaxially nested in the second inner cavity; the clamping member is used to fix the puncture needle and make the tip of the puncture needle extend out from the bottom end of the inner sleeve;

[0011] A first elastic body, the first elastic body surrounding the clamping member between the top end of the inner sleeve and the top wall of the first inner cavity.

[0012] Furthermore, a placement platform for placing a universal level is horizontally extended outward from the top edge of the outer sleeve.

[0013] Furthermore, the clamping member includes an operation part and a clamping part, the outer diameter of the top end of the clamping part being smaller than the outer diameter of the bottom end of the operation part;

[0014] A flange is provided near the bottom end of the inner sleeve in the second inner cavity;

[0015] An inwardly concave first clamping groove is provided at the bottom end of the operation part; the operation part extends from the top end of the outer sleeve and is slidably coaxially nested in the second inner cavity;

[0016] The top end of the clamping part extends from the bottom end of the inner sleeve and is clamped with the first clamping groove, and the bottom end of the clamping part abuts against the flange, and a second elastic body surrounds the outer side wall of the clamping part between the flange and the bottom end of the operation part.

[0017] Furthermore, the operation part and the clamping part are provided with an accommodation cavity axially penetrating through, the inner diameter of the accommodation cavity being adapted to the outer diameter of the puncture needle to guide the axial movement of the puncture needle;

[0018] And a clip combination composed of a plurality of closable clips is provided circumferentially at the bottom end of the clamping part, the clip combination being used to clamp the puncture needle; the clip combination can be clamped and retracted into the second inner cavity and abut against the flange.

[0019] Further, at least one clamping block adapted to the first clamping groove is provided along the axial direction at the top end of the clamping portion.

[0020] Further, a handle portion is provided horizontally outward at the top end of the operating portion extending out of the outer sleeve tube.

[0021] A second clamping groove adapted to the handle portion is provided at the top end of the outer sleeve tube.

[0022] Further, a first scale mark is provided along the axial direction on the outer side wall of the inner sleeve tube, and the first scale mark is used to indicate the axial displacement amount of the inner sleeve tube.

[0023] Further, a distance adjusting member is connected to the bottom of the outer side wall of the inner sleeve tube through a linear displacement adjusting mechanism, and the distance adjusting member is used to move along the axial direction of the inner sleeve tube through the linear displacement adjusting mechanism.

[0024] Further, the linear displacement adjusting mechanism includes:

[0025] An external thread provided around the bottom of the outer side wall of the inner sleeve tube and an internal thread provided around the inner side wall of the distance adjusting member, and the internal thread is adapted to the external thread.

[0026] Further, a second scale mark is provided along the axial direction on the outer side wall of the distance adjusting member, and the second scale mark is used to indicate the axial displacement amount of the distance adjusting member.

[0027] Compared with the prior art, the present invention has at least the following beneficial effects:

[0028] 1. By the retraction length of the inner sleeve tube relative to the outer sleeve tube and the elastic deformation condition of the first elastic body in the present invention, the purpose of accurately positioning the intervertebral disc on the XY axis can be achieved without imaging assistance, accurately distinguishing the intervertebral disc and the vertebra, without worrying about the harm caused by exposing the experimenter (rat) to the X-ray of the imaging assistance, and without the need to purchase expensive X-ray fluoroscopy equipment, reducing the cost and threshold; and the minimally invasive intervertebral disc positioning device of the present invention can repeatedly and accurately achieve the positioning of the intervertebral disc, simplifying the experimental process and improving the stability and repeatability of the acupuncture modeling; and it can also feedback the ability to train beginners to position the intervertebral disc through the accurate positioning of the minimally invasive intervertebral disc positioning device of the present invention, reducing the training cost and the difficulty of getting started.

[0029] 2. The present invention can also achieve the purpose of accurately positioning the intervertebral disc on the XYZ axis without imaging assistance through the cooperation of the universal level, accurately distinguishing the intervertebral disc and the vertebra, without worrying about the harm caused by exposing the experimenter (rat) to the X-ray of the imaging assistance. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the technical field to which this invention belongs; the terms used in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit the present invention; the terms "comprising" and "having" and any variations thereof in the specification and claims of the present invention and the above drawings are intended to cover non-exclusive inclusion. The terms "first", "second", etc. in the specification and claims of the present invention or the above drawings are used to distinguish different objects and not to describe a specific order.

[0031] To more clearly illustrate the technical solutions in the embodiments of the present invention, the following will briefly introduce the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0032] Figure 1 It is a cross-sectional view of a minimally invasive intervertebral disc positioning device proposed by the present invention with a puncture needle tool installed;

[0033] Figure 2 It is a schematic structural diagram of a minimally invasive intervertebral disc positioning device proposed by the present invention;

[0034] Figure 3 It is a schematic connection structure diagram of an operation part and a clamping part proposed by the present invention;

[0035] Figure 4 It is a cross-sectional view of another minimally invasive intervertebral disc positioning device proposed by the present invention with a puncture needle tool installed.

[0036] Reference numerals:

[0037] 10. Outer sleeve; 101. First inner cavity; 102. Placement platform; 103. Second card slot; 104. Limiting block; 105. Friction pattern;

[0038] 20. Inner sleeve; 201. Second inner cavity; 2011. First accommodation cavity; 2012. Second accommodation cavity; 202. Flange;

[0039] 30. Clamping member; 301. Operation part; 3011. First card slot; 302. Clamping part; 3021. Clamping block; 303. Accommodation cavity; 304. Clip; 305. Handle part; 306. Conical space;

[0040] 40. First elastic body;

[0041] 50. Second elastic body;

[0042] 60. Spacing adjustment member;

[0043] 70. Linear displacement adjustment mechanism; 701. External thread; 702. Internal thread;

[0044] 80. Puncture needle device. Detailed implementation mode

[0045] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention. Thus, a feature pointed out in this specification will be used to illustrate one feature of one embodiment of the present invention, rather than implying that each embodiment of the present invention must have the feature described. In addition, it should be noted that this specification describes many features. Although some features may be combined together to show possible system designs, these features may also be used in other combinations not explicitly described. Thus, unless otherwise stated, the described combinations are not intended to be limiting.

[0046] The principle and structure of the present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0047] In some embodiments, as Figure 1 shown, the present invention provides a minimally invasive disc positioning device that can accurately position the disc on the XY axis without the aid of imaging assistance, including:

[0048] Outer sleeve 10, the outer sleeve 10 has a first inner cavity 101 extending axially;

[0049] Inner sleeve 20, the inner sleeve 20 is slidably nested in the first inner cavity 101, and the inner sleeve 20 has a second inner cavity 201 extending axially;

[0050] Clamping member 30, the clamping member 30 extends from the top end of the outer sleeve 10 and is slidably coaxially nested in the second inner cavity 201; the clamping member 30 is used to fix the puncture needle device 80 and make the tip of the puncture needle device 80 extend out from the bottom end of the inner sleeve 20;

[0051] First elastic body 40, the first elastic body 40 surrounds the clamping member 30 between the top end of the inner sleeve 20 and the top wall of the first inner cavity 101.

[0052] It can be understood that the shapes of the outer sleeve 10, the inner sleeve 20 and the clamping member 30 proposed in this embodiment are preferably cylindrical; similarly, the shapes of the first inner cavity 101 and the second inner cavity 201 are preferably cylindrical. The puncture needle 80 proposed in this embodiment includes but is not limited to injection needles, infusion needles, etc., which are not limited herein. The first elastic body 40 proposed in this embodiment is preferably a compression spring.

[0053] It should be noted that the bottom end of the outer sleeve 10 is equivalent to the end where the outer sleeve 10 is nested with the inner sleeve 20, and the top end of the outer sleeve 10 is equivalent to the other end of the outer sleeve 10 away from its nested position (this nested position is the position where the outer sleeve 10 is nested with the inner sleeve 20), the same applies throughout the text; similarly, the top end of the inner sleeve 20 is equivalent to the end where the inner sleeve 20 is nested with the outer sleeve 10, and the bottom end of the inner sleeve 20 is equivalent to the other end of the inner sleeve 20 away from its nested position, the same applies throughout the text. And the top wall of the first inner cavity 101 is in the same direction as the top end of the outer sleeve 10.

[0054] In this way, when it is necessary to use the minimally invasive intervertebral disc positioning device to position the intervertebral disc, the operator can first fixedly clamp the corresponding puncture needle 80 through the clamping member 30 to ensure that the puncture needle 80 does not shake, and it is necessary to ensure that the tip of the puncture needle 80 extends out of the bottom end of the inner sleeve 20 by a second preset length, thereby completing the installation of the puncture needle 80.

[0055] Then, a 200g male SD rat is anesthetized by intraperitoneal injection of 2 ml of 2.5% (volume fraction) tribromoethanol. After the rat is anesthetized, its tail is straightened, and the position of the subcutaneous blood vessels is marked to avoid it. The position of the intervertebral disc is roughly judged by bending the rat's tail manually and marked with a circle. Subsequently, the rat's tail is disinfected with iodophor. Then the operator pinches or holds the outer sleeve 10, makes the puncture needle 80 perpendicular to the rat's tail, then selects a point from the marked circle and inserts the needle from the midpoint of the left and right widths of the tail. When the puncture needle 80 encounters an obstacle, the first elastic body 40 begins to undergo elastic deformation, and it can be seen that the inner sleeve 20 retracts into the outer sleeve 10. At this time, if the retracted length of the inner sleeve 20 reaches the first preset length and the first elastic body 40 has not yet reset, it indicates that the position where the puncture needle 80 punctures here can be regarded as the vertebra, and the puncture can be stopped. After pulling out the puncture needle 80, continue to select different points in the marked circle for puncture; if the retracted length of the inner sleeve 20 does not reach the first preset length and the first elastic body 40 resets and the inner sleeve 20 extends out of the outer sleeve 10, it indicates that the position where the puncture needle 80 punctures here is the intervertebral disc, and the puncture needle 80 has entered the intervertebral disc, and then enter the subsequent experimental steps.

[0056] Therefore, according to the retraction length of the inner sleeve 20 relative to the outer sleeve 10 and the elastic deformation of the first elastomer 40 in the present invention, the purpose of accurately positioning the intervertebral disc on the XY axis can be achieved without the assistance of imaging (equivalent to an X-ray fluoroscopy device), accurately distinguishing the intervertebral disc from the vertebrae, without worrying about the harm caused by exposing the experimenter (rat) to the X-rays of the imaging assistance, and without the need to purchase expensive X-ray fluoroscopy equipment, reducing costs and thresholds; moreover, the minimally invasive intervertebral disc positioning device of the present invention can repeatedly and accurately achieve the positioning of the intervertebral disc, simplifying the experimental process and improving the stability and repeatability of acupuncture modeling; and it can also feedback and train the ability of beginners to position the intervertebral disc through the accurate positioning of the minimally invasive intervertebral disc positioning device of the present invention, reducing the training cost and the difficulty of getting started.

[0057] It should be noted that the principle of the minimally invasive intervertebral disc positioning device to distinguish the intervertebral disc from the vertebrae through the first elastomer 40 is as follows:

[0058] The needle of the puncture needle 80 will encounter resistance when it meets the intervertebral disc and the vertebra. When the force applied to the needle reaches the resistance threshold, the needle will break through these two tissue structures. The existence of the first elastomer 40 can quantify the force applied to the needle. When the needle with the first elastomer 40 meets the intervertebral disc and the vertebra, first, the force applied to the needle has not reached the resistance threshold, and the needle cannot break through the tissue structure. The first elastomer 40 undergoes elastic deformation to reflect the magnitude of the force. Then, when the force applied to the needle reaches the resistance threshold, the needle will break through the corresponding tissue structure, and the first elastomer 40 will reset. At this time, it can also be feedback to the operator that the needle has penetrated the tissue structure. Since the resistance threshold of the intervertebral disc is smaller than that of the vertebra, the puncture site can be distinguished as the intervertebral disc or the vertebra by comparing the magnitude of the quantified thrust force with the resistance threshold (in actual operation, the elastic deformation amount of the first elastomer 40 can be compared to reflect the thrust force and the resistance threshold). That is, when the magnitude of the thrust force is greater than the resistance threshold of the intervertebral disc and the first elastomer 40 has not reset yet, it can be determined that the site is the vertebra, which achieves the purpose of accurately positioning the intervertebral disc on the XY axis.

[0059] Moreover, according to existing literature research and actual experiments, using a 25G (thin model) sharp needle for the needle of the puncture needle tool 80 to perform intervertebral disc puncture will not exacerbate intervertebral disc degeneration (Pfirrmann grading). Because the diameter of the 25G puncture needle is only 0.53mm, significantly smaller than that of the traditional 18G needle (>1mm), the mechanical damage to the annulus fibrosus and surrounding tissues during the puncture process is smaller, reducing the risk of postoperative inflammatory reaction and annulus fibrosus rupture; and the 25G thin needle puncture has lower requirements for the patient's body position (such as lumbar puncture does not require a strict "lobster-like" position), is suitable for patients with limited mobility (such as lower limb fractures or pregnant women), and improves the operation safety. Therefore, this proves that although the minimally invasive intervertebral disc positioning device locates the intervertebral disc by puncturing the intervertebral disc, it will not cause major damage to the intervertebral disc when using a 25G thin model needle, belonging to a minimally invasive positioning method. And the minimally invasive intervertebral disc positioning device itself punctures through a needle and also belongs to percutaneous channel puncture. Therefore, the entire surgical needle puncture modeling process also belongs to minimally invasive surgery.

[0060] In some embodiments, to ensure that the minimally invasive intervertebral disc positioning device can accurately position the intervertebral disc in the Z-axis direction (or axial direction), as Figure 1 - Figure 2 shown, a placement platform 102 for placing a universal level is horizontally extended outward from the top edge of the outer sleeve 10.

[0061] It should be noted that in this embodiment, the top wall of the placement platform 102 and the top wall of the outer sleeve 10 are on the same horizontal plane; and the main body of the placement platform 102 is rectangular, and its end is seamlessly connected to a standard circular area to form a continuous overall shape.

[0062] Among them, a universal level is a tool that uses the action of gravity and the movement of bubbles in a liquid to detect whether the surface of an object is horizontal or vertical.

[0063] The universal level is internally equipped with multiple sealed glass tubes. Each sealed glass tube is filled with a liquid (such as alcohol or ether) and has a bubble left; different sealed glass tubes respectively detect horizontal, vertical or a specific angle (such as 45°) to achieve multi-directional calibration. This embodiment takes the example of detecting the accuracy in the vertical direction.

[0064] And the sealed glass tube is designed as a slightly curved arc surface to ensure that the bubble automatically moves to the highest point under the action of gravity. When the universal level is placed on a horizontal surface, the bubble will stay centered between the scale lines at the top of the arc of the sealed glass tube, indicating that it is vertical at this time; if the surface is tilted, the bubble will deviate from the center, and the deviation direction is opposite to the tilt direction, and the deviation distance reflects the degree of tilt.

[0065] Therefore, in this embodiment, by means of the retraction length of the inner sleeve 20 relative to the outer sleeve 10 and the elastic deformation of the first elastomer 40, the purpose of accurately positioning the intervertebral disc on the XY axes is achieved; then, in cooperation with a universal level, the purpose of accurately positioning the intervertebral disc on the Z axis is achieved, so that the purpose of accurately positioning the intervertebral disc on the XYZ axes can be achieved without the aid of imaging, accurately distinguishing the intervertebral disc from the vertebrae, without worrying about the harm caused by exposing the experimenter (rat) to the X-rays of imaging assistance, and without the need to purchase expensive X-ray fluoroscopy equipment, reducing costs and thresholds; moreover, the minimally invasive intervertebral disc positioning device of the present invention can achieve the positioning of the intervertebral disc repeatedly and more accurately, simplifying the experimental process and improving the stability and repeatability of acupuncture modeling and puncture drug administration; furthermore, the ability to train beginners to position the intervertebral disc can be feedback through the accurate positioning of the minimally invasive intervertebral disc positioning device of the present invention, reducing the training cost and the difficulty of getting started.

[0066] In some embodiments, as Figure 2 shown, the outer side wall of the outer sleeve 10 is circumferentially provided with friction lines 105, which increase the microscopic roughness of the contact surface, causing greater resistance when the operator touches the outer sleeve 10 and preventing the minimally invasive intervertebral disc positioning device from falling out of the operator's hand.

[0067] In some embodiments, as Figure 1 and Figure 3 shown, the clamping member 30 includes an operating portion 301 and a clamping portion 302 that detachably clamps the puncture needle 80, and the outer diameter of the top end of the clamping portion 302 is smaller than the outer diameter of the bottom end of the operating portion 301;

[0068] A ring-shaped flange 202 is provided near the bottom end of the inner sleeve 20 in the second inner cavity 201;

[0069] The bottom end of the operating portion 301 is provided with an inwardly recessed first clamping groove 3011; the bottom end of the operating portion 301 extends from the top end of the outer sleeve 10 and is slidably and coaxially nested in the second inner cavity 201;

[0070] The top end of the clamping portion 302 extends from the bottom end of the inner sleeve 20 and is snap-fitted with the first clamping groove 3011, and the bottom end of the clamping portion 302 abuts against the flange 202, and a second elastomer 50 is wound around the outer side wall of the clamping portion 302 between the flange 202 and the bottom end of the operating portion 301.

[0071] It should be noted that the shapes of the operating portion 301 and the clamping portion 302 proposed in this embodiment are preferably cylindrical. Of course, the shapes of the operating portion 301 and the clamping portion 302 can also be prismatic or other suitable shapes, which are not limited herein. The second elastomer 50 in this embodiment is preferably a compression spring.

[0072] Wherein, the flange 202 divides the second inner cavity 201 into a first accommodation cavity 2011 and a second accommodation cavity 2012, and the inner diameter of the first accommodation cavity 2011 is greater than that of the second accommodation cavity 2012 which is greater than the inner diameter of the annular flange 202; the outer diameter of the bottom end of the clamping part 302 is greater than that of the rest of the clamping part 302, and the outer diameter of the bottom end of the clamping part 302 is greater than the inner diameter of the annular flange 202 and less than the inner diameter of the second accommodation cavity 2012, ensuring that the top end of the clamping part 302 can smoothly pass through the flange 202 into the first accommodation cavity 2011, and the bottom end of the clamping part 302 cannot pass through the flange 202.

[0073] It can be seen that the bottom end of the operating part 301 extends from the top end of the outer sleeve 10 and is slidably and coaxially nested in the first accommodation cavity 2011; the top end of the clamping part 302 extends from the bottom end of the inner sleeve 20 and is snap-fitted with the first clamping groove 3011, and the bottom end of the clamping part 302 is located in the second accommodation cavity 2012 and abuts against the flange 202.

[0074] In this way, when the needle of the puncture needle 80 that meets the use requirements needs to be clamped by the clamping part 302, the operating part 301 can be first pressed downwards. At this time, the second elastic body 50 undergoes elastic deformation, and at the same time, the bottom end of the clamping part 302 is pushed out of the second accommodation cavity 2012 by the operating part 301. At this time, the bottom end of the clamping part 302 is in a loose state, facilitating the placement of the needle of the puncture needle 80; then the operating part 301 is released. At this time, the operating part 301 will reset due to the elastic deformation of the second elastic body 50, thereby driving the bottom end of the clamping part 302 to re-enter the second accommodation cavity 2012. At this time, the bottom end of the clamping part 302 will tightly enclose together in the second accommodation cavity 2012 and be in a clamped state to fix the needle of the puncture needle 80 to prevent shaking or loosening, so as to perform the next experimental step.

[0075] And because the outer diameter of the bottom end of the operating part 301 is greater than the inner diameter of the annular flange 202, it can prevent the bottom end of the operating part 301 from passing through the flange 202, ensuring that the operating part 301 will not fall off the inner sleeve 20 when being pressed.

[0076] In some embodiments, to ensure that the clamping part 302 can better clamp the puncture needle 80, as Figure 1 shown, the operating part 301 and the clamping part 302 are provided with an accommodation cavity 303 along the same axis, and the inner diameter of the accommodation cavity 303 is adapted to the outer diameter of the puncture needle 80 to guide the axial movement of the puncture needle 80;

[0077] And a clip combination composed of a plurality of enclosable clips 304 is provided along the circumferential direction at the bottom end of the clamping part 302, and the clip combination is used for clamping the puncture needle 80; the clip combination can be matched and clamped to retract into the second inner cavity 201 and abut against the flange 202.

[0078] In this way, when the operator presses down the operation part 301, at this time the second elastic body 50 undergoes elastic deformation, and at the same time the clip combination is pushed out of the second accommodation cavity 2012 by the operation part 301. At this time, the clip combination is dispersed and in a loose state. Then the operator inserts the needle of the puncture needle device 80 into the accommodation cavity 303 from the top end of the operation part 301 until it extends out of the clip combination. Then the extending length of the needle of the puncture needle device 80 is adjusted to the second preset length. After the adjustment is completed, the operator releases the operation part 301. At this time, the operation part 301 will reset due to the elastic deformation of the second elastic body 50, and then drive the clip combination to re-enter the second accommodation cavity 2012. During the re-entry process, the clip combination will be gradually clamped by the side wall of the second accommodation cavity 2012 and then tightly clamp the needle of the puncture needle device 80, and then the next experimental step is carried out.

[0079] In some embodiments, as Figure 1 and Figure 3 shown, a conical space 306 is provided in the middle of the accommodation cavity 303 of the clamping part 302. The inner diameter of the conical space 306 decreases successively along the insertion direction of the needle of the puncture needle device 80 until it reaches a constant inner diameter value and remains unchanged. This facilitates the smooth insertion of the needle of the puncture needle device 80 into the accommodation cavity 303 and its extension out of the clip combination.

[0080] In some embodiments, to ensure that the operation part 301 and the clamping part 302 form a detachable connection, as Figure 3 shown, at least one clamping block 3021 adapted to the first clamping groove 3011 is provided axially at the top end of the clamping part 302.

[0081] Among them, in this embodiment, it is exemplified that two clamping blocks 3021 are provided axially at the top end of the clamping part 302, and both of the two clamping blocks 3021 are clamped with a first clamping groove 3011. In this way, the clamping part 302 can rock up and down along the axial direction to reduce the normal pressure between the clamping block 3021 and the corresponding first clamping groove 3011, and further reduce the friction between the clamping block 3021 and the corresponding first clamping groove 3011, so that the clamping part 302 can be detached from the operation part 301. Of course, according to the actual situation, one, three or more clamping blocks 3021 can also be provided axially at the top end of the clamping part 302, which is not limited here.

[0082] In some embodiments, the contact surface of the clip 304 in the clip combination for clamping the needle is frosted and rough to increase the friction between the clip combination and the needle, and ensure that the clamping part 302 can more stably clamp the needle of the puncture needle device 80.

[0083] In some embodiments, as Figure 2As shown, on both sides of the top end of the operating portion 301 extending out of the outer sleeve 10 in the horizontal direction, handle portions 305 are provided outwardly.

[0084] At the top end of the outer sleeve 10, a second card slot 103 adapted to the handle portion 305 is provided.

[0085] It should be noted that at the top end of the outer sleeve 10, two opposite limiting blocks 104 are circumferentially provided with its center as the midpoint. The limiting blocks 104 are arc-shaped, and a second card slot 103 is formed between the limiting blocks 104 and the top end of the outer sleeve 10 below them; each handle portion 305 is engaged with a corresponding second card slot 103.

[0086] In this way, the operator first rotates the handle portion 305 to engage with the corresponding second card slot 103, and then presses down the operating portion 301. At this time, the second elastic body 50 undergoes elastic deformation, and at the same time, the clip combination is pushed out of the second accommodation cavity 2012 by the operating portion 301. At this time, the clip combination is dispersed and in a loose state. Then, the operator extends the needle of the puncture needle device 80 (preferably a sharp needle with a length of more than 4 cm of 25G model) from the top end of the operating portion 301 into the accommodation cavity 303 until it extends out of the clip combination. Then, the needle of the puncture needle device 80 is adjusted to extend to the second preset length. At this time, only the second elastic body 50 undergoes elastic deformation, and the first elastic body 40 is not affected. In this way, the situation where the first elastic body 40 also undergoes elastic deformation when the second elastic body 50 undergoes elastic deformation can be avoided.

[0087] If the handle portion 305 is not rotated to engage with the corresponding second card slot 103 first, and only the second elastic body 50 needs to undergo elastic deformation, the operator needs to hold or grasp both the handle portion 305 and the inner sleeve 20 at the same time, which is inconvenient for single-handed operation (because the other hand needs to hold the puncture needle device 80), and the needle is a sharp object, so care needs to be taken to avoid being stabbed. After the handle portion 305 is rotated to engage with the corresponding second card slot 103 first, the operator can press down the operating portion 301 with only one finger of one hand to push the clip combination out of the second accommodation cavity 2012 and into a loose state. Then, the operator uses the other hand to extend the needle of the puncture needle device 80 from the top end of the operating portion 301 into the accommodation cavity 303 until it extends out of the clip combination. Then, the needle of the puncture needle device 80 is adjusted to extend the second preset length, which can simplify the operation difficulty.

[0088] Then the operator releases the operating portion 301. At this time, the operating portion 301 will reset due to the elastic deformation of the second elastic body 50, and then drive the clip combination to re-enter the second accommodation cavity 2012. During the re-entry process, the clip combination will be gradually clamped tightly by being squeezed by the side wall of the second accommodation cavity 2012, and then tightly clamp the needle of the puncture needle device 80, thereby completing the installation of the puncture needle device 80.

[0089] Then, a 200g male SD rat was anesthetized by intraperitoneal injection of 2 ml of 2.5% (by volume) tribromoethanol. After the rat was anesthetized, its tail was straightened, and the positions of the subcutaneous blood vessels were marked to avoid them. The position of the intervertebral disc was roughly judged by bending the rat's tail manually and marked with a circle. Subsequently, the rat's tail was disinfected with iodophor. The rat's tail was placed horizontally on the table. Then, the operator pinched or held the outer sleeve 10, and the puncture needle 80 was perpendicular to the rat's tail. When the bubble of the universal level was at the center, it indicated that the puncture needle 80 was perpendicular to the rat's tail. Then, a point was selected from the marked circle, and the needle was inserted from the midpoint of the left and right widths of the tail. When the puncture needle 80 encountered an obstacle, the first elastic body 40 began to undergo elastic deformation, and it could be seen that the inner sleeve 20 retracted into the outer sleeve 10. At this time, if the retracted length of the inner sleeve 20 reached the first preset length (8 mm) and the first elastic body 40 had not yet reset, it indicated that the position where the puncture needle 80 punctured here could be regarded as the vertebra, and the puncture should be stopped. Then, after pulling out the puncture needle 80, different points were selected from the marked circle for puncture; if the retracted length of the inner sleeve 20 did not reach the first preset length (8 mm) and the first elastic body 40 reset and the inner sleeve 20 extended out of the outer sleeve 10, it indicated that the position where the puncture needle 80 punctured here was the intervertebral disc and the puncture needle 80 had entered the intervertebral disc. This demonstrated the operation process of using the minimally invasive intervertebral disc positioning device to position the intervertebral disc, and it was also possible to feedback and train the ability of beginners to position the intervertebral disc through this positioning.

[0090] In some embodiments, a first scale mark (not shown, the same throughout the text) is provided along the axial direction on the outer sidewall of the inner sleeve 20, and the first scale mark is used to indicate the axial displacement amount of the inner sleeve 20.

[0091] It should be noted that the first scale mark proposed in this embodiment is preferably millimeter scale lines arranged at equal intervals and corresponding digital marks, and the scale lines and digital marks of the first scale mark are formed by laser etching or UV printing, and a transparent wear-resistant layer is covered on the surfaces of the scale lines and digital marks, and the material of the transparent wear-resistant layer is polyurethane or epoxy resin.

[0092] This can clearly show the length of the inner sleeve 20 retracted into the outer sleeve 10, and in combination with the elastic deformation condition of the first elastic body 40, to further improve the accuracy of positioning the intervertebral disc.

[0093] In some embodiments, to finely adjust the puncture length of the needle, so as to accurately control the depth of needle insertion, which helps to accurately insert the needle to the predetermined depth after measuring and determining the depth of the intervertebral disc by the instrument and achieve accurate positioning on the Z-axis, as Figure 1 shown, a distance adjusting member 60 is connected to the bottom of the outer sidewall of the inner sleeve 20 through a linear displacement adjusting mechanism 70, and the linear displacement adjusting mechanism 70 is used to drive the distance adjusting member 60 to move along the axial direction of the inner sleeve 20.

[0094] It should be noted that the shape of the distance adjusting member 60 is preferably a hollow cylindrical shape.

[0095] Because according to the actual situation, the needle insertion length of the minimally invasive intervertebral disc positioning device varies. For example:

[0096] Since the height of the horizontally placed rat tail varies due to individual differences, and the needle insertion length of the minimally invasive intervertebral disc positioning device is half of the height of the rat tail. Because when the height of the rat tail is different, the operator can adjust the distance adjusting member 60 to move along the axial direction of the inner sleeve 20, thereby increasing or decreasing the exposed length of the needle of the puncture needle tool 80 (equivalent to the needle insertion length of the puncture needle tool 80), so that the exposed length of the needle of the puncture needle tool 80 is half of the height of the rat tail.

[0097] Specifically, this embodiment proposes the structure of one of the linear displacement adjusting mechanisms 70, and the linear displacement adjusting mechanism 70 includes:

[0098] An external thread 701 provided around the bottom of the outer side wall of the inner sleeve 20 and an internal thread 702 provided around the inner side wall of the distance adjusting member 60, and the internal thread 702 is adapted to the external thread 701.

[0099] In this way, when the operator needs to adjust the distance adjusting member 60, the distance adjusting member 60 can be rotated, so that the distance adjusting member 60 moves along the axial direction of the inner sleeve 20, thereby changing the needle insertion length of the puncture needle tool 80.

[0100] For the convenience of understanding, when the distance adjusting member 60 proposed in this embodiment rotates one circle, the needle insertion length of the puncture needle tool 80 will change by 1.5 mm. For example, when the distance adjusting member 60 rotates one circle clockwise, the needle insertion length of the puncture needle tool 80 will increase by 1.5 mm; similarly, when the distance adjusting member 60 rotates one circle counterclockwise, the needle insertion length of the puncture needle tool 80 will decrease by 1.5 mm. Of course, the needle insertion length changed by the distance adjusting member 60 rotating one circle can be changed according to the actual situation, and is not limited to 1.5 mm.

[0101] Of course, in other embodiments (not shown in the figure), the linear displacement adjusting mechanism 70 includes:

[0102] At least one guiding groove provided on the outer side wall of the inner sleeve 20 and extending axially, and a guiding slider provided on the inner side wall of the distance adjusting member 60 and adapted to the guiding groove. And the bottom end of the inner sleeve 20 is slidably nested inside the distance adjusting member 60. At the same time, the guiding slider is in sliding fit with the corresponding guiding groove, and the cross section of the guiding groove is T-shaped, and the head size of the guiding slider is slightly smaller than the T-shaped space of the guiding groove, so that the distance adjusting member 60 can slide along the axial direction of the inner sleeve 20 but cannot rotate.

[0103] Moreover, a first limiting protrusion is provided on the outer sidewall of the bottom end of the inner sleeve 20, and a second limiting protrusion is provided on the inner sidewall of the distance adjusting member 60 facing the top end of the outer sleeve 10. In this way, when the distance adjusting member 60 moves towards the bottom end of the inner sleeve 20, the guiding slider slides along the guiding groove until the second limiting protrusion contacts the first limiting protrusion of the inner sleeve 20, and at this time, the maximum extended position is reached. Similarly, when moving in the reverse direction (the distance adjusting member 60 moves towards the top end of the inner sleeve 20), the distance adjusting member 60 can be retracted to the initial position.

[0104] Moreover, at least one threaded hole penetrating through the outer sidewall is provided on the outer sidewall of the distance adjusting member 60, and a locking bolt is also provided in a matching manner for the threaded hole, and the threaded hole and the corresponding locking bolt form a locking assembly. And an elastic pressing member is provided at the end of the locking bolt. The elastic pressing member is preferably a silica gel gasket with a thickness of 2 mm, and the surface of the gasket is processed with diamond anti-slip lines with a depth of 0.5 mm. When the locking bolt is screwed into the corresponding threaded hole, the elastic pressing member will form a surface contact lock with the outer sidewall of the inner sleeve 20, and the position is locked through friction.

[0105] In some embodiments, a second scale mark (not shown, the same throughout the text) is provided on the outer sidewall of the distance adjusting member 60 along the axial direction, and the second scale mark is used to indicate the axial displacement amount of the distance adjusting member 60.

[0106] It should be noted that the second scale mark proposed in this embodiment is preferably millimeter scale lines (0.1 mm) arranged at equal intervals and corresponding digital marks, and the scale lines and digital marks of the second scale mark are formed by laser etching or UV printing, and a transparent wear-resistant layer is covered on the surface of the scale lines and digital marks. The material of the transparent wear-resistant layer is polyurethane or epoxy resin.

[0107] In this way, the length of the distance adjusting member 60 on the inner sleeve 20 can be clearly known, and the needle insertion length of the puncture needle 80 can be accurately controlled.

[0108] In another embodiment, how to use the minimally invasive intervertebral disc positioning device for acupuncture modeling is shown, and the specific process is as follows:

[0109] Anesthetize a 300 g male SD rat by intraperitoneal injection of 2.5 ml of 2.5% (by volume) tribromoethanol. After the rat is anesthetized, straighten its tail, mark the position of the subcutaneous blood vessels to avoid, roughly judge the position of the intervertebral disc by manually bending the rat's tail and draw a circle to mark it, and measure the height of this section of the rat's tail.

[0110] Then, rotate the handle part 305 to engage with the corresponding second card slot 103, and then press down the operating part 301. At this time, the second elastic body 50 undergoes elastic deformation, and at the same time, the clip combination is pushed out of the second accommodation cavity 2012 by the operating part 301. At this time, the clip combination is dispersed and in a loose state. Then, the operator inserts the needle of the puncture needle device 80 (preferably a sharp needle with a length greater than 4 cm of 18G model) into the accommodation cavity 303 from the top of the operating part 301 until it extends out of the clip combination by a second preset length. Then, the operator releases the operating part 301. At this time, the operating part 301 will reset due to the elastic deformation of the second elastic body 50, and then drive the clip combination to re-enter the second accommodation cavity 2012, thereby tightly clamping the needle of the puncture needle device 80 to complete the installation of the puncture needle device 80. After that, adjust the distance adjusting member 60 so that the length of the needle tip exposed by the puncture needle device 80 is half of the height of the rat's tail.

[0111] Subsequently, disinfect the rat's tail with iodophor, place the rat's tail horizontally on the table, and then the operator pinches or holds the outer sleeve 10. Keep the puncture needle device 80 perpendicular to the rat's tail. When the bubble of the universal level is at the center, it indicates that the puncture needle device 80 is perpendicular to the rat's tail. Then, select a point from the marking circle and insert the needle at the midpoint of the left and right widths of the tail.

[0112] At this time, if the retracted length of the inner sleeve 20 reaches the first preset length (8 mm) and the first elastic body 40 has not been reset yet, it indicates that the puncture position of the puncture needle device 80 here can be regarded as the vertebra, and the puncture should be stopped. Then, after pulling out the puncture needle device 80, continue to select different points in the marking circle for puncture; if the retracted length of the inner sleeve 20 does not reach the first preset length (8 mm) and the first elastic body 40 resets and the inner sleeve 20 extends out of the outer sleeve 10, it indicates that the puncture position of the puncture needle device 80 here is the intervertebral disc and the puncture needle device 80 has entered the intervertebral disc. When the needle enters the intervertebral disc, fully insert the needle exposed outside the distance adjusting member 60 into the rat's tail, then rotate for 10 s, stay for 60 s, and then pull out the needle. Disinfect the rat's tail again to complete the model establishment.

[0113] In another embodiment, as Figure 4 shown, it shows how to use the minimally invasive intervertebral disc positioning device for minimally invasive puncture drug delivery. The specific process is as follows:

[0114] Among them, the puncture needle device 80 proposed in this embodiment is preferably a micro syringe.

[0115] Anesthetize a 300 g male SD rat by intraperitoneal injection of 2.5 ml of 2.5% (volume fraction) tribromoethanol. After the rat is anesthetized, straighten its tail, mark the position of the subcutaneous blood vessels to avoid them, roughly judge the position of the intervertebral disc by manually bending the rat's tail and draw a circle for marking, and measure the height of this section of the rat's tail.

[0116] Then rotate the handle part 305 to engage with the corresponding second card slot 103, and then press down the operation part 301. At this time, the second elastic body 50 undergoes elastic deformation, and at the same time, the clip combination is pushed out of the second accommodation cavity 2012 by the operation part 301. At this time, the clip combination is dispersed and in a loose state. Then the operator inserts the needle of the micro syringe into the accommodation cavity 303 from the top of the operation part 301 until it extends out of the clip combination by a second preset length. Then the operator releases the operation part 301. At this time, the operation part 301 will reset due to the elastic deformation of the second elastic body 50, and then drive the clip combination to re-enter the second accommodation cavity 2012, so as to tightly clamp the needle of the micro syringe and complete the installation of the micro syringe. Then adjust the distance adjusting part 60 so that the length of the needle exposed by the micro syringe is half of the height of the rat's tail.

[0117] Subsequently, disinfect the rat's tail with iodophor. Place the rat's tail horizontally on the table, and then the operator pinches or holds the outer sleeve 10, and holds the micro syringe perpendicular to the rat's tail. When the bubble of the universal level is at the center, it indicates that the micro syringe is perpendicular to the rat's tail. Then select a point from the marking circle and insert the needle at the midpoint of the left and right widths of the tail.

[0118] At this time, if the retracted length of the inner sleeve 20 reaches the first preset length (8 mm) and the first elastic body 40 has not yet reset, it indicates that the puncture position of the micro syringe here can be regarded as the vertebra, and the puncture should be stopped. Then pull out the micro syringe and continue to select different points in the marking circle for puncture; if the retracted length of the inner sleeve 20 does not reach the first preset length (8 mm) and the first elastic body 40 resets and the inner sleeve 20 extends out of the outer sleeve 10, it indicates that the puncture position of the micro syringe here is the intervertebral disc and the micro syringe has entered the intervertebral disc. When the needle enters the intervertebral disc, completely insert the needle exposed from the distance adjusting part 60 into the rat's tail, then slowly push the medicine. After the medicine pushing is completed, pull out the needle, and disinfect the rat's tail again to complete the minimally invasive puncture drug delivery of the intervertebral disc.

[0119] Therefore, the minimally invasive intervertebral disc positioning device proposed in this embodiment can clamp the micro syringe for injection drug delivery, can highly integrate the realization of intervertebral disc positioning puncture and injection drug delivery, the experimental process is simple, and the modeling effect is stable and easy to repeat.

[0120] Obviously, the embodiments described above are only a part of the embodiments of the present invention, rather than all of them. The preferred embodiments of the present invention are shown in the drawings, but they do not limit the patent scope of the present invention. The present invention can be implemented in many different forms. On the contrary, the purpose of providing these embodiments is to make the understanding of the disclosed content of the present invention more thorough and comprehensive. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing specific embodiments or equivalently replace some of the technical features. Any equivalent structure made by using the content of the specification and drawings of the present invention, directly or indirectly applied in other related technical fields, is similarly within the scope of the patent protection of the present invention.

Claims

1. A minimally invasive intervertebral disc positioning device, characterized in that: include: An outer sleeve (10), wherein the outer sleeve (10) has a first inner cavity (101) extending axially; An inner sleeve (20), the inner sleeve (20) being slidably nested in the first inner cavity (101), the inner sleeve (20) having a second inner cavity (201) extending in the axial direction; a clamping member (30), the clamping member (30) extending from the top end of the outer sleeve (10) and slidably and coaxially nested in the second inner cavity (201); the clamping member (30) is used to fix the puncture needle (80) and make the tip of the puncture needle (80) extend from the bottom end of the inner sleeve (20); A first elastic body (40), wherein the first elastic body (40) surrounds the clamping member (30) between the top end of the inner sleeve (20) and the top wall of the first inner cavity (101).

2. The minimally invasive intervertebral disc positioning device according to claim 1, characterized in that: A placement platform (102) for placing a universal level instrument is horizontally extended outward from the top edge of the outer sleeve (10).

3. The minimally invasive intervertebral disc positioning device according to claim 1, characterized in that: The clamping member (30) comprises an operating portion (301) and a clamping portion (302), wherein the outer diameter of the top end of the clamping portion (302) is smaller than the outer diameter of the bottom end of the operating portion (301); The second inner cavity (201) is provided with a flange (202) near the bottom end of the inner sleeve (20); The bottom end of the operating portion (301) is provided with a first recessed groove (3011) that is recessed inwards; the operating portion (301) extends from the top end of the outer sleeve (10) and is slidably and coaxially nested in the second inner cavity (201); The top end of the clamping portion (302) extends from the bottom end of the inner sleeve (20) and is clamped with the first clamping groove (3011), and the bottom end of the clamping portion (302) is in contact with the flange (202), and the outer side wall of the clamping portion (302) between the flange (202) and the bottom end of the operating portion (301) is surrounded by a second elastic body (50).

4. The minimally invasive intervertebral disc positioning device according to claim 3, characterized in that: The operating portion (301) and the clamping portion (302) are provided with an accommodating cavity (303) penetrating along the same axial direction, and the inner diameter of the accommodating cavity (303) is adapted to the outer diameter of the puncture needle (80) to guide the axial movement of the puncture needle (80); A clip assembly consisting of a plurality of enclosed clips (304) is circumferentially disposed at the bottom end of the clamping portion (302), and the clip assembly is used to clamp the puncture needle (80); the clip assembly can match and clamp the retracted second inner cavity (201) and abut against the flange (202).

5. The minimally invasive intervertebral disc positioning device according to claim 3, characterized in that: At least one clamping block (3021) adapted to the first clamping groove (3011) is axially disposed at the top end of the clamping portion (302).

6. The minimally invasive intervertebral disc positioning device according to claim 3, characterized in that: A handle portion (305) is provided at the top end of the operating portion (301) extending outward from the outer sleeve (10) in a horizontal direction; The top end of the outer sleeve (10) is provided with a second slot (103) adapted to the handle portion (305).

7. The minimally invasive intervertebral disc positioning device according to claim 1, characterized in that: The outer wall of the inner sleeve (20) is provided with a first scale mark along the axial direction, and the first scale mark is used to indicate the axial displacement of the inner sleeve (20).

8. The minimally invasive intervertebral disc positioning device according to claim 1, characterized in that: The bottom of the outer side wall of the inner sleeve (20) is connected to a distance adjusting member (60) via a linear displacement adjusting mechanism (70), and the linear displacement adjusting mechanism (70) is used to drive the distance adjusting member (60) to move along the axial direction of the inner sleeve (20).

9. The minimally invasive intervertebral disc positioning device according to claim 8, characterized in that: The linear displacement adjustment mechanism (70) comprises: An external thread (701) is arranged around the bottom of the outer wall of the inner sleeve (20) and an internal thread (702) is arranged around the inner wall of the distance adjusting member (60), and the internal thread (702) is adapted to the external thread (701).

10. The minimally invasive intervertebral disc positioning device according to claim 8, characterized in that: The outer side wall of the distance adjusting member (60) is provided with a second scale mark along the axial direction, and the second scale mark is used to indicate the axial displacement of the distance adjusting member (60).

Images