Hose clamp valve for filling machine and corresponding filling machine

Abstract

The present application relates to the field of filling machines using isolators, and specifically discloses a hose clamp valve (1) for a filling machine, comprising: a mounting structure (11) adapted to be mounted on an isolator wall (2); the clamping valve structure (12) is positioned on the first side of the mounting structure (11) and is used for clamping a hose; a drive device (13) at least partially located on a second side of the mounting structure (11) opposite the first side; and a transmission device (14) for transmitting the driving action of the driving device (13) across the isolator wall (2) to the pinch valve structure (12). The invention further discloses a corresponding filling machine comprising the hose clamp valve (1). According to some exemplary embodiments of the invention, the hose clamp valve can be operated by a single hand, the overall space is smaller, the user operation is more convenient, the cost is lower, and the hose clamp valve is arranged on an isolator and is also very convenient to implement.

Description

Technical Field

[0001] The present application relates to a hose pinch valve for a filling machine and a corresponding filling machine. Background Art

[0002] In the field of filling, especially in the field of drug filling, filling machines are usually used to fill drugs into corresponding containers, such as glass bottles. After filling, the container can be sealed to enclose the drug in the container.

[0003] In actual drug filling, due to strict hygiene requirements such as a sterile environment, restricted access barrier systems (RABS) or isolators are widely used. They are special purification devices designed to provide a locally air-purified environment and achieve physical isolation from the outside world. In this case, the layout position of the hose pinch valve is usually restricted, and it is necessary not to cause contamination problems when operating the hose pinch valve. For this reason, the hose pinch valve located inside the restricted access barrier system or isolator is usually operated through a glove box.

[0004] The operation through the glove box is a non-direct contact operation. Therefore, it greatly affects the operation of the operator, and even causes abnormal operation due to improper operation.

[0005] In addition, with the introduction of new regulations, in order to ensure the sterility of products, pharmaceutical factories are required to conduct an online integrity test of product filters before the start of liquid pharmaceutical production. However, due to limitations such as the double-layer glass and cavity space of the isolator, when conducting the online integrity test, operators often face problems such as difficult operation and unsatisfactory test results. In this trend, it is urgent to design a more efficient and convenient online integrity test system.

[0006] Currently, when many pharmaceutical factories conduct product filter integrity tests before production, they often configure CIPSIP-like pipelines or use off-line test methods. These methods have disadvantages such as high cost, long test process time, large floor space, and difficult operation.

[0007] Therefore, corresponding improvements are needed. Summary of the Invention

[0008] In order to overcome at least one of the above-mentioned disadvantages and / or other possible disadvantages that may not be mentioned herein, the object of the present application is to provide an improved hose pinch valve for a filling machine and a corresponding filling machine.

[0009] According to one aspect of the present application, there is provided a hose pinch valve for a filling machine, the hose pinch valve comprising: a mounting structure adapted to be mounted on an isolator wall; a pinch valve structure for pinching a hose located on a first side of the mounting structure; a driving device at least partially located on a second side of the mounting structure opposite to the first side; and a transmission device for transmitting a driving action of the driving device across the isolator wall to the pinch valve structure.

[0010] According to an alternative embodiment of the present application, the pinch valve structure is configured to be suitable for single-handed operation.

[0011] According to an alternative embodiment of the present application, the driving device is configured as a pneumatic driving device.

[0012] According to an alternative embodiment of the present application, the transmission device is configured to extend through the mounting structure.

[0013] According to an alternative embodiment of the present application, the transmission device is configured as a transmission rod capable of linear motion.

[0014] According to an alternative embodiment of the present application, the mounting structure is configured to be mounted on the isolator wall in a sealed manner.

[0015] According to an alternative embodiment of the present application, the mounting structure includes a base that is held on the isolator wall at least partially on the same side as the pinch valve structure in the mounted state.

[0016] According to an alternative embodiment of the present application, the mounting structure includes a holding device that is held on the isolator wall at least partially on the opposite side of the pinch valve structure relative to the isolator wall in the mounted state.

[0017] According to an alternative embodiment of the present application, the transmission device includes an elastic preloading device such that the hose pinch valve is default in a normally closed state.

[0018] According to an alternative embodiment of the present application, the pinch valve structure is held on the base.

[0019] According to an alternative embodiment of the present application, the driving device is connected to the holding device.

[0020] According to an alternative embodiment of the present application, the base is connected to the holding device.

[0021] According to an alternative embodiment of the present application, the elastic preloading device includes a helical spring.

[0022] According to an alternative embodiment of the present application, the holding device is configured to include at least one support rod, and in the installed state, the support rod is connected between the base and the driving device across the isolator wall.

[0023] According to an alternative embodiment of the present application, the at least one support rod includes a plurality of support rods, the plurality of support rods are arranged at intervals from each other, and the transmission device is located between the plurality of support rods.

[0024] According to an alternative embodiment of the present application, a first groove for receiving a hose is formed on the end face of the base facing away from the driving device, and a through channel for receiving the transmission device is formed on the base, and the through channel intersects and communicates with the first groove to allow the transmission device to operate on the hose located in the first groove.

[0025] According to an alternative embodiment of the present application, the pinch valve structure includes a pinch cover capable of moving relative to the base, and the pinch cover is configured to be able to transform at least between a release state allowing the release of the hose and a restricted state restricting the outer periphery of the hose and not allowing release.

[0026] According to an alternative embodiment of the present application, the pinch cover is pivotally held on the base around a first pivot axis towards the first groove.

[0027] According to an alternative embodiment of the present application, the pinch cover is formed with a second groove capable of cooperating with the first groove to jointly embrace the hose in the restricted state.

[0028] According to an alternative embodiment of the present application, the pinch cover is configured to allow pre-holding of the hose.

[0029] According to an alternative embodiment of the present application, in the installed state, the first pivot axis is parallel to the isolator wall.

[0030] According to an alternative embodiment of the present application, the first pivot axis is perpendicular to the extrusion direction of the transmission device on the hose.

[0031] According to an alternative embodiment of the present application, the first groove is configured to be arc-shaped.

[0032] According to an alternative embodiment of the present application, the second groove is configured to be arc-shaped, especially an arc with a central angle greater than 180 degrees to allow pre-holding of the hose.

[0033] According to an alternative embodiment of the present application, the pinch valve structure further includes a locking device for keeping the pinch cover in the restricted state.

[0034] According to an optional embodiment of the present application, the locking device is configured as a handle that can pivot along the second pivot axis.

[0035] According to an optional embodiment of the present application, in the installed state, the second pivot axis is perpendicular to the isolator wall.

[0036] According to an optional embodiment of the present application, the second pivot axis is arranged non-parallel to the first pivot axis.

[0037] According to an optional embodiment of the present application, the handle is configured to keep the clamp cover in the restricted state by pivoting and pressing against an end surface of the clamp cover facing away from the first groove.

[0038] According to an optional embodiment of the present application, the clamping cover is arranged on the end surface of the base opposite to the handle.

[0039] According to an optional embodiment of the present application, the first pivot axis and the second pivot axis are arranged perpendicular to each other.

[0040] According to an optional embodiment of the present application, a boss is formed on the end surface of the clamping cover, and the boss is provided with a guide slope. The handle can climb to the top of the boss along the guide slope during the pivoting process to lock the clamping cover.

[0041] According to an optional embodiment of the present application, a locking groove is provided on the top of the boss, and the locking groove is configured to indicate the locking state of the handle through an operational frustration feeling and to lock the handle in the locking groove with a predetermined locking force.

[0042] According to another aspect of the present application, a filling machine is provided, wherein the filling machine comprises the hose clamp valve for the filling machine according to any one of the above embodiments.

[0043] According to an optional embodiment of the present application, the filling machine includes an isolator and a glove box arranged on the wall of the isolator. In the installed state, the clamping valve structure is located inside the isolator, and the driving device is located outside the isolator. The clamping valve structure can be manually operated through the glove box.

[0044] According to certain embodiments of the present application, the hose clamp valve can be operated with one hand, the overall space is smaller, the user operation is more convenient, the cost is lower, and it is also very convenient to implement when arranged on an isolator. BRIEF DESCRIPTION OF THE DRAWINGS

[0045] The present invention will be described in more detail below with reference to the accompanying drawings and exemplary embodiments, so that the principles, features and advantages of the present invention can be better understood. The accompanying drawings include:

[0046] Figure 1 Shows a perspective view of a hose clamp valve according to an exemplary embodiment of the present application mounted on the isolator wall of a filling machine (not shown) from a first perspective.

[0047] Figure 2 Shows the hose clamp valve shown in Figure 1 a perspective view from a second perspective different from the first perspective.

[0048] Figure 3 From a third perspective slightly different from the Figure 2 second perspective of Figure 1 shows the hose clamp valve shown in

[0049] Figure 4 Shows a side view of the hose clamp valve shown in Figure 1 a locked state in a partial cut-away view.

[0050] Figure 5 Shows Figure 4 a side view of the hose clamp valve shown in an open or unlocked state. Detailed Description

[0051] In order to make the technical problems to be solved, technical solutions and beneficial technical effects of the present application more clearly understood, the present application will be further described in detail below in conjunction with the drawings and multiple exemplary embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application, rather than to limit the protection scope of the present application.

[0052] Before formally starting the description, it should be noted that due to the view angle and the spatial limitation of the reference numerals marked in the drawings, some reference numerals are not marked in all views. Therefore, when referring to the description, if necessary, multiple views can be referred to simultaneously for easy understanding, but this does not mean that each feature must appear simultaneously in all embodiments. On the contrary, whether each feature can be changed or replaced and whether it is necessary should be limited by whether the technical solution can be implemented.

[0053] Figure 1 Shows a perspective view of a hose clamp valve according to an exemplary embodiment of the present application mounted on the isolator wall of a filling machine (not shown) from a first perspective.

[0054] Figure 2 Shows the hose clamp valve shown in Figure 1 a perspective view from a second perspective different from the first perspective.

[0055] Figure 3 From a third perspective slightly different from the Figure 2 second perspective of Figure 1Perspective view of the hose clamp valve shown.

[0056] Figure 4 Is shown in a partial cross-sectional view Figure 1 Side view of the hose clamp valve shown in the locked state.

[0057] Figure 5 Shows Figure 4 Side view of the hose clamp valve shown in the open or unlocked state.

[0058] The centralized display of these figures can better and more quickly convey the basic idea of the present application to those skilled in the art. However, it is obvious that these are only some exemplary embodiments.

[0059] As Figures 1 - 5 Shown, according to a first aspect of the present application, there is provided a hose clamp valve 1 for a filling machine, comprising: a mounting structure 11 adapted to be mounted on an isolator wall 2; a clamp valve structure 12 for clamping a hose located on a first side of the mounting structure 11; a driving device 13 at least partially located on a second side of the mounting structure 11 opposite to the first side; and a transmission device 14 for transmitting the driving action of the driving device 13 across the isolator wall 2 to the clamp valve structure 12.

[0060] In this way, the clamp valve structure 12 can be arranged inside the isolator, while the driving device 13 that may cause contamination inside the isolator is arranged outside the isolator. Here, for simplicity, only a part of the isolator wall is schematically shown. During operation, when the hose is correctly loaded into the hose clamp valve 1, the driving device 13 can automatically control the working state of the hose clamp valve 1 without manual operation. The operator only needs to manually load and unload the hose.

[0061] Obviously, when the hose clamp valve 1 is arranged on the isolator, there should be no leakage caused by the structure of the hose clamp valve 1 itself. In this case, in particular, it is necessary to ensure that there is no leakage path in the channel through which the transmission device 14 passes. The present application does not describe the sealing measures in more detail because on the one hand, those skilled in the art understand this, and on the other hand, the structure of the hose clamp valve 1 of the present application can well achieve this.

[0062] According to an exemplary embodiment of the present application, the clamp valve structure 12 can be configured to be suitable for single-handed operation, that is, it allows the operator to operate the clamp valve structure 12 with one hand (especially the right hand) to load the hose onto the clamp valve structure 12 and lock it, and to remove the hose from the clamp valve structure 12 in the locked state.

[0063] According to an exemplary embodiment of the present application, the driving device 13 can be configured as an electrically controlled pneumatic driving device, such as a cylinder. In this case, the transmission device 14 is preferably configured as a transmission rod capable of linear motion.

[0064] As Figures 1 - 5 shown, according to an exemplary embodiment of the present application, the transmission device 14 is configured to extend through the mounting structure 11, so that a compact arrangement can be achieved.

[0065] As described above, in order to ensure the sealing performance, the mounting structure 11 is configured to be suitable for sealingly mounting on the isolator wall 2.

[0066] According to an exemplary embodiment of the present application, the mounting structure 11 includes a base 111 that is held on the isolator wall 2 at least partially on the same side as the pinch valve structure 12 (i.e., the inner side of the isolator) in the mounted state.

[0067] According to an exemplary embodiment of the present application, the mounting structure 11 includes holding means 112 that are held on the isolator wall 2 at least partially on the opposite side of the pinch valve structure 12 with respect to the isolator wall 2 (i.e., the outer side of the isolator) in the mounted state.

[0068] As Figures 4 - 5 shown, according to an exemplary embodiment of the present application, the transmission device 14 includes an elastic preloading device 141 to keep the hose pinch valve 1 in a normally closed state by default.

[0069] According to an exemplary embodiment of the present application, the elastic preloading device 141 may include a helical spring, especially implemented as a helical spring. In this case, the helical spring may be sleeved on the transmission device 14, such as a transmission rod.

[0070] As Figures 1 - 5 shown, according to an exemplary embodiment of the present application, the pinch valve structure 12 is held on the base 111.

[0071] As Figures 1 - 5 shown, according to an exemplary embodiment of the present application, the drive device 13 is connected to the holding means 112.

[0072] As Figures 1 - 5 shown, according to an exemplary embodiment of the present application, the base 111 is connected to the holding means 112.

[0073] In particular, the drive device 13, the holding means 112 and the base 111 are connected to each other.

[0074] As Figures 1 - 5 shown, according to an exemplary embodiment of the present application, the holding means 112 is configured to include at least one support rod 1121, which spans the isolator wall 2 and is connected between the base 111 and the drive device 13 in the mounted state.

[0075] As Figures 1 - 5As shown, according to an exemplary embodiment of the present application, the at least one support rod 1121 includes a plurality of support rods 1121 (four in the figure), the plurality of support rods 1121 are arranged at intervals from each other, and the transmission device 14 is located between the plurality of support rods 1121.

[0076] In particular, the cylinder head of the cylinder can be square, with a support rod 1121 arranged at each corner, and the transmission device 14 can be arranged at the center position of the square.

[0077] As Figures 1 - 5 shown, according to an exemplary embodiment of the present application, on the end face of the base 111 facing away from the driving device 13 (i.e., the end face facing away from the isolator wall 2), a first groove 1111 for receiving a hose is formed, and a through-channel 1112 for receiving the transmission device 14 is formed in the base 111. The through-channel 1112 intersects and communicates with the first groove 1111 to allow the transmission device 14 to operate on the hose located in the first groove 1111. In other words, the transmission device 14, for example a transmission rod, can extend from the through-channel 1112 to squeeze the hose sitting in the first groove 1111. The provision of the first groove 111 provides a suitable seating position for the hose. Obviously, the first groove 1111 is preferably arc-shaped.

[0078] As Figures 1 - 5 shown, according to an exemplary embodiment of the present application, the pinch valve structure 12 includes a pinch cover 121 that can move relative to the base 111. The pinch cover 121 is configured to be able to transform at least between a release state allowing the release of the hose and a restricted state restricting the outer periphery of the hose and not allowing release. In the release state, the hose can be detached from the pinch valve structure 12, and in the restricted state, the transmission device 14 can correctly squeeze the hose to allow control of the flow characteristics of the hose.

[0079] As described above, since the pinch valve structure 12 is located inside the isolator, the operator can only operate the pinch valve structure 12 through, for example, the glove box. Therefore, the convenience of operation is very important, especially the ability to operate with one hand is more advantageous. It is very beneficial to place the hose by rotating the pinch cover 121 in this way.

[0080] As Figures 1 - 5 shown, according to an exemplary embodiment of the present application, the pinch cover 121 is pivotally held on the base 111 so as to be able to pivot around a first pivot axis towards the first groove 1111. Since the first groove 1111 is located on the end face of the base 111, only by moving the pinch cover 121 back and forth by hand can the opening or closing of the pinch cover 121 be achieved, which is very convenient to operate.

[0081] According to an exemplary embodiment of the present application, as Figures 1 - 5As shown, the clamping cover 121 is formed with a second groove 1211 that can cooperate with the first groove 1111 to jointly embrace the hose in the restricted state.

[0082] According to an exemplary embodiment of the present application, the clamping cover 121 can be configured to allow pre-holding of the hose. In other words, the hose can be relatively stably held on the clamping cover 121 and can reliably move along with the clamping cover 121. In this case, opening the clamping cover 121 can disengage the hose from the action of the transmission device 14, and closing the clamping cover 121 can cause the transmission device 14 to act on the hose. Moreover, due to the movability of the clamping cover 121, it is also very convenient to pre-fix the hose to the clamping cover 121.

[0083] As a possible implementation manner of the present application, as Figures 1 - 5 shown, the second groove 1211 can be configured to be arc-shaped, especially an arc with a central angle greater than 180 degrees, for example 240 degrees, to allow pre-holding of the hose. The hose can be appropriately squeezed and deformed and laterally inserted into the second groove 1211, and then can be reliably held therein.

[0084] Those skilled in the art can understand that other methods can also be used for pre-holding the hose, such as other structures provided on the clamping cover 121. The present application does not limit this, as long as it can facilitate the hose to be held on the clamping cover 121 and can move along with the clamping cover 121.

[0085] According to an exemplary embodiment of the present application, in the installed state, the first pivot axis is parallel to the isolator wall 2.

[0086] According to an exemplary embodiment of the present application, the first pivot axis is perpendicular to the extrusion direction of the transmission device 14 on the hose.

[0087] If the base 111 is integrally cylindrical, the first pivot axis can be perpendicular to the central axis of the base 111. At this time, the first pivot axis can be arranged adjacent to the outer peripheral edge of the base 111.

[0088] To reliably hold the clamping cover 121 in the restricted state, according to an exemplary embodiment of the present application, as Figures 1 - 5 shown, the pinch valve structure 12 further includes a locking device 122 for keeping the clamping cover 121 in the restricted state.

[0089] As Figures 1 - 5 shown, the locking device 122 is configured as a handle that can pivot along the second pivot axis, for example, in the shape of a rod.

[0090] According to an exemplary embodiment of the present application, the handle is configured to be able to keep the clamping cover 121 in the restricted state by pivoting and pressing against the end face of the clamping cover 121 that faces away from (especially in the restricted state) the first groove 1111. This direct pressing is very reliable, and the pivoting of the handle is also very easy to achieve for single-handed operation through the glove box.

[0091] According to an exemplary embodiment of the present application, in the installed state, the second pivot axis is arranged non-parallel to the first pivot axis, and preferably perpendicular to the isolator wall 2.

[0092] According to an exemplary embodiment of the present application, the first pivot axis and the second pivot axis are arranged perpendicular to each other. For example, the second pivot axis can be arranged parallel to the extrusion direction of the hose by the transmission device 14.

[0093] According to an exemplary embodiment of the present application, the clamping cover 121 and the handle are arranged opposite to each other on the end face of the base 111. This means that the connection point of the clamping cover 121 and the base 111 and the connection point of the handle and the base 111 are arranged opposite to each other, especially facing each other. For example, when the base 111 is cylindrical as a whole, they are arranged radially opposite to each other. Or, more generally speaking, the clamping cover 121 and the handle are arranged opposite to each other with respect to the transmission device 14 or the through hole 1112.

[0094] The second pivot axis is preferably also provided at the outer peripheral edge of the base 111.

[0095] In order to stably and reliably keep the clamping cover 121 in the restricted state, according to an exemplary embodiment of the present application, a convex platform 1212, especially in a strip shape, is formed on the end face of the clamping cover 121 (the end face facing away from the first groove 1111), and the convex platform 1212 is provided with a guiding ramp (especially can be clearly seen from Figure 1 ), and the handle can climb along the guiding ramp to the top of the convex platform 1212 during pivoting to lock the clamping cover 121.

[0096] Especially because the pinch valve structure 12 is arranged in the isolator, the operation of the operator more depends on the sense of touch. Therefore, according to an exemplary embodiment of the present application, a locking groove is provided at the top of the convex platform 1212 (can be seen from Figure 2 and Figure 3 ), and the locking groove is configured to be able to indicate the locking state of the handle through the operation jerks and be able to lock the handle in the locking groove with a predetermined locking force.

[0097] This means that when the handle rotates around the second pivot axis and slides on the boss 1212, there will be a sense of jerk at the locking groove, which can enable the operator to feel this. At the same time, the handle can be seated in the locking groove, and only by applying a certain torque can the handle be disengaged from the locking groove, which can achieve more reliable locking.

[0098] When installing a certain hose on the hose clamp valve 1, the hose can be first pre-fixed to the clamp cover 121, for example, fixed in the second groove 1211, and then the clamp cover 121 is rotated so that the hose is correctly positioned within the space jointly enclosed by the first groove 1111 and the second groove 1211. Subsequently, the handle is rotated to press the handle against the end face of the clamp cover 121, thereby achieving reliable locking. By performing the reverse operation, the hose can be detached. It can be seen that the hose clamp valve 1 of the present application is convenient to operate and can be completed with one hand.

[0099] Moreover, the structure of the hose clamp valve 1 of the present application is simple, the cost is relatively low, and the layout is relatively compact, providing layout flexibility for being arranged on the isolator wall.

[0100] According to a second aspect of the present application, there is provided a filling machine, wherein the filling machine includes a hose clamp valve 1 for a filling machine according to any one of the above exemplary embodiments.

[0101] According to an exemplary embodiment of the present application, the filling machine includes an isolator and a glove box (not shown) provided on the isolator wall 2. In the installed state, the clamp valve structure 12 is located inside the isolator, and the driving device 13 is located outside the isolator. The clamp valve structure 12 can be manually operated through the glove box.

[0102] Although specific embodiments of the present application are described in detail herein, they are given only for the purpose of explanation and should not be considered as limiting the scope of the present application. Various substitutions, changes and modifications can be conceived without departing from the spirit and scope of the present application.

Claims

1. A hose pinch valve (1) for a filling machine, comprising: a mounting structure (11) adapted to be mounted on an isolator wall (2); a pinch valve structure (12) for clamping a hose located on a first side of the mounting structure (11); a drive device (13) at least partially located on a second side of the mounting structure (11) opposite to the first side; and a transmission device (14) for transmitting a driving action of the drive device (13) across the isolator wall (2) to the pinch valve structure (12).

2. The hose pinch valve (1) for a filling machine according to claim 1, wherein, the pinch valve structure (12) is configured to be suitable for single - hand operation; and / or the drive device (13) is configured as a pneumatic drive device; and / or the transmission device (14) is configured to extend through the mounting structure (11); and / or the transmission device (14) is configured as a transmission rod capable of linear motion; and / or the mounting structure (11) is configured to be mounted on the isolator wall (2) in a sealed manner.

3. The hose pinch valve (1) for a filling machine according to claim 1 or 2, wherein, the mounting structure (11) includes a base (111) that is held on the isolator wall (2) at least partially on the same side as the pinch valve structure (12) in the mounted state; and / or the mounting structure (11) includes a holding device (112) that is held on the isolator wall (2) at least partially on the opposite side of the pinch valve structure (12) relative to the isolator wall (2) in the mounted state; and / or the transmission device (14) includes an elastic pre - loading device (141) to keep the hose pinch valve (1) in a normally - closed state by default.

4. The hose pinch valve (1) for a filling machine according to claim 3, wherein, the pinch valve structure (12) is held on the base (111); and / or the drive device (13) is connected to the holding device (112); and / or the base (111) is connected to the holding device (112); and / or the elastic pre - loading device (141) includes a helical spring.

5. The hose pinch valve (1) for a filling machine according to claim 3 or 4, wherein, the holding device (112) is configured to include at least one support rod (1121), and in the mounted state, the support rod (1121) connects the base (111) and the drive device (13) across the isolator wall (2).

6. The hose pinch valve (1) for a filling machine according to claim 5, wherein, the at least one support rod (1121) includes a plurality of support rods (1121) that are arranged at intervals from each other, and the transmission device (14) is located between the plurality of support rods (1121).

7. The hose pinch valve (1) for a filling machine according to any one of claims 3 - 6, wherein, On the end face of the base (111) facing away from the drive device (13), a first groove (1111) for receiving a hose is formed, and the base (111) is formed with a through-channel (1112) for receiving the transmission device (14). The through-channel (1112) intersects and communicates with the first groove (1111) to allow the transmission device (14) to operate on the hose located in the first groove (1111); and / or The pinch valve structure (12) includes a pinch cover (121) that can move relative to the base (111). The pinch cover (121) is configured to be able to transform at least between a release state allowing the release of the hose and a restricted state restricting the outer periphery of the hose and not allowing release.

8. The hose pinch valve (1) for a filling machine according to claim 7, wherein, The pinch cover (121) is pivotally held on the base (111) so as to be able to pivot towards the first groove (1111) about a first pivot axis; and / or The pinch cover (121) is formed with a second groove (1211) that can cooperate with the first groove (1111) to jointly embrace the hose in the restricted state; and / or The pinch cover (121) is configured to allow pre-holding of the hose.

9. The hose pinch valve (1) for a filling machine according to claim 8, wherein, In the installed state, the first pivot axis is parallel to the isolator wall (2); and / or The first pivot axis is perpendicular to the extrusion direction of the transmission device (14) on the hose; and / or The first groove (1111) is configured to be arc-shaped; and / or The second groove (1211) is configured to be arc-shaped, especially an arc with a central angle greater than 180 degrees to allow pre-holding of the hose.

10. The hose pinch valve (1) for a filling machine according to any one of claims 7-9, wherein, The pinch valve structure (12) further includes a locking device (122) for keeping the pinch cover (121) in the restricted state.

11. The hose pinch valve (1) for a filling machine according to claim 10, wherein, The locking device (122) is configured as a handle that can pivot along a second pivot axis.

12. The hose pinch valve (1) for a filling machine according to claim 11, wherein, In the installed state, the second pivot axis is perpendicular to the isolator wall (2); and / or The second pivot axis is arranged non-parallel to the first pivot axis; and / or The handle is configured to be able to keep the pinch cover (121) in the restricted state by pivoting and pressing against the end face of the pinch cover (121) facing away from the first groove (1111).

13. The hose pinch valve (1) for a filling machine according to claim 12, wherein, The pinch cover (121) and the handle are arranged opposite to each other on the end face of the base (111); and / or The first pivot axis and the second pivot axis are arranged perpendicular to each other; and / or A boss (1212) is formed on the end face of the clamping cover (121), and a guiding slope is provided on the boss (1212). The handle can climb along the guiding slope to the top of the boss (1212) during pivoting to lock the clamping cover (121).

14. The hose clamp valve (1) for a filling machine according to claim 13, wherein, a locking groove is provided at the top of the boss (1212). The locking groove is configured to indicate the locking state of the handle through an operating sense of jerk and to lock the handle in the locking groove with a predetermined locking force.

15. A filling machine, wherein, the filling machine includes the hose clamp valve (1) for a filling machine according to any one of claims 1-14.

16. The filling machine according to claim 15, wherein, the filling machine includes an isolator and a glove box provided on the wall (2) of the isolator. In the installed state, the clamp valve structure (12) is located inside the isolator, and the driving device (13) is located outside the isolator. The clamp valve structure (12) can be manually operated through the glove box.

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