Crushing equipment suitable for carbamazepine tablet medicine raw materials

Abstract

The crushing equipment comprises a crushing box, the top end of the outer surface of the crushing box fixedly communicates with a feeding frame, the outer surface of the lower end of the crushing box fixedly communicates with a discharging frame, and the interior of the crushing box is fixedly connected with a filter plate; a motor is arranged at the position, close to the upper portion, of the outer surface of one side of the smashing box, and the output end of the motor penetrates into the smashing box and is fixedly connected with a rotating rod. Through mutual cooperation of cleaning brushes on the surfaces of a crushing roller and a rotating roller, the crushing roller and the rotating roller can move along the surface of a filter plate to crush medicine raw materials, and the crushing roller and the rotating roller can be driven to rotate, so that the medicine raw materials are ground and crushed by grinding strips on the surface of the crushing roller; and the rotating roller drives the cleaning brush to rotate to scatter the rolled medicine raw materials, so that the medicine raw materials are prevented from blocking filter holes due to caking in the crushing process.

Description

Technical Field

[0001] The present invention relates to the technical field of pharmaceutical raw material processing, and particularly relates to a pulverizing device suitable for the raw materials of carbamazepine tablets. Background Art

[0002] Carbamazepine tablets are mainly used for the treatment of epilepsy, and are also commonly used for the treatment of peripheral neuralgia, manic depression, arrhythmia and other diseases. Clinically, they are generally used as the first choice drug for the treatment of epilepsy. Carbamazepine is a drug with low solubility and high permeability. Clinically, a large dose of drug administration is required to ensure good bioavailability, and the bioavailability is usually limited by its dissolution rate. If the dissolution rate increases, it may lead to a significant improvement in bioavailability. Therefore, improving the dissolution rate is the key to improving its bioavailability.

[0003] In order to improve the dissolution rate of poorly water-soluble drugs, common methods include micronization to reduce particle size, spray drying to prepare solid dispersions, nanocrystallization and other technologies. A carbamazepine solid tablet and its preparation method with the existing patent publication number CN115089555A adopt a hot melt extrusion technology to make carbamazepine more uniformly dispersed in the carrier material, and the dissolution rate of carbamazepine tablets is significantly improved, which helps to improve the drug efficacy; the addition of a plasticizer also significantly improves the long-term stability of carbamazepine tablets; However, in the process of preparing carbamazepine solid tablets by the above technical solutions, carbamazepine needs to be pulverized, screened and then mixed and crushed with raw materials such as plasticizers. In the actual operation process, the pulverized powder after crushing is prone to caking under the action of external force rollers and adheres to the surface of the rolling rollers, which not only affects the continuous pulverization of the rolling rollers, but also is not conducive to the pulverized powder passing through the sieve holes, reducing the pulverization efficiency. Summary of the Invention

[0004] The purpose of the present invention is to solve the problems in the prior art, and to provide a pulverizing device suitable for the raw materials of carbamazepine tablets.

[0005] In order to achieve the above purpose, the present invention adopts the following technical solution: A pulverizing device suitable for the raw materials of carbamazepine tablets, including a pulverizing box, the top end of the outer surface of the pulverizing box is fixedly communicated with a feeding frame, and the lower outer surface of the pulverizing box is fixedly communicated with a discharging frame; A filter plate is fixedly connected inside the pulverizing box, and a motor is arranged at a position close to the upper part on one outer surface of the pulverizing box. The output end of the motor penetrates into the inside of the pulverizing box and is fixedly connected with a rotating rod. A plurality of groups of crushing blades are fixedly connected to the outer surface of the rotating rod, and a pulverizing mechanism is arranged between the rotating rod and the filter plate; A material guiding cavity is arranged inside the pulverizing box at a position below the filter plate, and a material passing component for preventing the filter plate and the discharging frame from being blocked is arranged inside the material guiding cavity.

[0006] Further, the crushing mechanism includes a first connecting plate, a crushing roller, a rolling bar, and a second connecting plate; the outer surface of the rotating rod is fixedly connected with a first connecting plate near both ends; a crushing roller is rotatably connected between the two first connecting plates; and a plurality of groups of rolling bars are fixedly connected to the outer surface of the crushing roller at equal intervals. The outer surface of the rolling bar is attached to the outer surface of the filter plate. The outer surface of the rotating rod is fixedly connected with a second connecting plate near both ends at positions on both sides of the first connecting plate. A rotating roller is fixedly connected between the corresponding two second connecting plates, and a cleaning brush is fixedly connected to the outer surface of the rotating roller.

[0007] Further, one end of both the crushing roller and the rotating roller is fixedly connected with a first rotating shaft, and one end of the first rotating shaft penetrates to the outside of the corresponding first connecting plate and the second connecting plate and is fixedly connected with a gear. An internal rack is fixedly connected to the inner surface of the crushing box at a position corresponding to the gear. The inner surface of the internal rack is arc-shaped. The gear meshes with the internal rack. One end of the outer surface of the crushing roller away from the first rotating shaft is fixedly connected with a second rotating shaft, and one end of the second rotating shaft penetrates to the outside of the corresponding first connecting plate and is connected with a cleaning component for scraping the surface of the crushing roller.

[0008] Further, the cleaning component includes a movable plate, a connecting strip, and a driving strip; the outer surfaces of the two first connecting plates are both movably connected with a movable plate. One end of the second rotating shaft penetrates to the outside of the corresponding first connecting plate and is fixedly connected with a connecting strip. One end of the outer surface of the connecting strip away from the second rotating shaft is rotatably connected with a driving strip, and one end of the driving strip is hinged to the corresponding movable plate.

[0009] Further, movable grooves are provided on both outer surfaces of the movable plate, and a spring and a movable column are arranged inside the movable grooves. One end of the movable column penetrates to the outside of the movable groove and is movably connected therewith. The two ends of the spring are respectively fixedly connected with the movable groove and the movable column. An L-shaped plate is fixedly connected between the two movable plates on the same side, and a scraping piece is fixedly connected to one side outer surface of the L-shaped plate.

[0010] Further, the material feeding component includes a driving wheel fixedly connected to one end of the rotating rod penetrating to the outside of the crushing box. A transmission wheel is rotatably connected to the outer surface of the crushing box at a position corresponding to the material guiding cavity through a connecting shaft. A conveyor belt is connected between the transmission wheel and the driving wheel. One end of the connecting shaft penetrates to the inside of the material guiding cavity and is fixedly connected with a material guiding plate. Collision balls are fixedly connected to both sides of the upper outer surface of the material guiding plate.

[0011] Further, the outer surface of the material guiding plate is arc-shaped, and two connecting rods are hinged to the position of the lower outer surface of the material guiding plate corresponding to the discharge frame. The bottom ends of the connecting rods penetrate to the outside of the discharge frame and are fixedly connected with a moving strip.

[0012] Furthermore, guide columns are fixedly connected to both sides of the outer surface of the discharge frame. The moving bar is movably connected to the guide columns, and movable holes are provided at positions corresponding to the guide columns on the outer surface of the moving bar. The cross-sectional area of the movable holes is larger than the cross-sectional area of the guide columns. A material guiding column is fixedly connected to the outer surface of the connecting rod.

[0013] In summary, due to the adoption of the above technical solutions, the beneficial effects of the present invention are as follows: 1. In the present invention, by setting the cleaning brushes on the surfaces of the crushing roller and the rotating roller to cooperate with each other, not only can the crushing roller and the rotating roller move along the surface of the filter plate to crush the pharmaceutical raw materials, but also the crushing roller and the rotating roller can be driven to rotate self - sufficiently, so that the rolling bars on the surface of the crushing roller can roll and crush the pharmaceutical raw materials. The rotating roller drives the cleaning brush to rotate to disperse the rolled pharmaceutical raw materials, preventing the pharmaceutical raw materials from caking during the crushing process and blocking the filter holes. In addition, while using the crushing roller and the rolling bars to crush the pharmaceutical raw materials, the scraping blade can be driven by the spring and the movable plate to move up and down along the surface of the crushing roller, so as to scrape the pharmaceutical raw materials adhered to the surface of the rolling bars and the crushing roller during the rolling and crushing process, preventing the pharmaceutical raw materials from caking on the surface of the rolling bars and the crushing roller due to excessive rolling during the long - term crushing process, and improving the crushing strength of the crushing roller.

[0014] 2. In the present invention, by setting the transmission between the rotating rod and the guide plate by using a conveyor belt, the power of driving the rotating rod by the motor can be used to make the guide plate rotate forward and backward, so that the collision balls repeatedly collide with the filter plate, accelerating the discharging rate of the filter plate and improving the uniformity of the distribution of the pharmaceutical raw materials on the surface of the filter plate. The pharmaceutical raw materials finally are discharged through the discharge frame. In addition, it can also use the forward and backward rotation of the guide plate to drive the connecting rod to move up and down inside the discharge frame, and at the same time, the connecting rod drives the material guiding column to swing left and right, preventing blockage inside the discharge frame during the discharging process and improving the discharging rate. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 is the overall structural schematic diagram of the present invention; Figure 2 is the combined view of the crushing mechanism and the material - passing component of the present invention; Figure 3 is the structural schematic diagram of the material - passing component of the present invention; Figure 4 is the structural schematic diagram of the cleaning component of the present invention; Figure 5 is the combined view of the movable plate and the crushing roller of the present invention; Figure 6 is the combined view of the movable plate and the scraping blade of the present invention; Figure 7Combined view of the scraper and the L-shaped plate of the present invention.

[0016] Reference numerals: 1, crushing box; 2, feeding frame; 3, discharging frame; 4, filter plate; 5, crushing blade; 6, rotating rod; 7, crushing mechanism; 71, connecting plate 1; 72, crushing roller; 73, rolling strip; 74, connecting plate 2; 75, cleaning brush; 76, gear; 77, internal rack; 8, cleaning component; 81, movable plate; 82, connecting strip; 83, driving strip; 84, spring; 85, movable column; 86, L-shaped plate; 87, scraper; 9, material passing component; 91, driving wheel; 92, transmission wheel; 93, conveyor belt; 94, guiding plate; 95, collision ball; 96, connecting rod; 97, moving strip; 98, guiding column; 99, material guiding column. Detailed implementation mode

[0017] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.

[0018] Example 1: As Figures 1-5 shown, a crushing device applicable to the raw materials of carbamazepine tablets proposed by the present invention includes a crushing box 1. The top end of the outer surface of the crushing box 1 is fixedly communicated with a feeding frame 2. The drug raw materials enter the inside of the crushing box 1 through the feeding frame 2, and the lower end outer surface of the crushing box 1 is fixedly communicated with a discharging frame 3; A filter plate 4 is fixedly connected inside the crushing box 1. A motor is arranged at a position near the upper part of one side outer surface of the crushing box 1. The output end of the motor penetrates into the inside of the crushing box 1 and is fixedly connected with a rotating rod 6. A plurality of groups of crushing blades 5 are fixedly connected to the outer surface of the rotating rod 6. The motor drives the rotating rod 6 to drive the crushing blades 5 to rotate 45 degrees left and right to initially crush the drug raw materials. The drug after initial crushing falls on the surface of the filter plate 4. Fine powders and particles enter the inside of the guiding cavity through the filter holes of the filter plate 4 and finally are discharged through the discharging frame 3 and enter the next processing procedure.

[0019] A crushing mechanism 7 is arranged between the rotating rod 6 and the filter plate 4. The crushing mechanism 7 includes a connecting plate 1 71, a crushing roller 72, a rolling strip 73 and a connecting plate 2 74. Connecting plates 1 71 are fixedly connected to positions near both ends of the outer surface of the rotating rod 6. A crushing roller 72 is rotatably connected between the two groups of connecting plates 1 71. A plurality of groups of rolling strips 73 are fixedly connected to the outer surface of the crushing roller 72 at equal intervals. The outer surface of the rolling strip 73 is attached to the outer surface of the filter plate 4; On the outer surface of the rotating rod 6 near both ends and on both sides of the connecting plate one 71, there are fixedly connected with connecting plates two 74. Between the corresponding two groups of connecting plates two 74, there is fixedly connected with a rotating roller, and on the outer surface of the rotating roller, there is fixedly connected with a cleaning brush 75. The connecting plate two 74 drives the corresponding rotating roller to move along the filter plate 4.

[0020] Both ends of the crushing roller 72 and the rotating roller are fixedly connected with a first rotating shaft. And one end of the first rotating shaft penetrates to the outside of the corresponding connecting plate one 71 and connecting plate two 74 and is fixedly connected with a gear 76. And on the inner surface of the crushing box 1 at the position corresponding to the gear 76, there is fixedly connected with an internal rack 77. The inner surface of the internal rack 77 is arc-shaped. The gear 76 meshes with the internal rack 77. Driven by the internal rack 77, the gear 76 drives the corresponding crushing roller 72 and rotating roller to rotate self. Therefore, the rolling strips 73 on the surface of the crushing roller 72 roll and crush the pharmaceutical raw materials with larger particles. The rotating roller drives the cleaning brush 75 to rotate and disperse the rolled pharmaceutical raw materials, preventing the pharmaceutical raw materials from caking during the crushing process and blocking the filter holes.

[0021] Embodiment 2: As Figures 1-7 shown, the difference between this embodiment and Embodiment 1 is that at one end of the outer surface of the crushing roller 72 far from the first rotating shaft, there is fixedly connected with a second rotating shaft. And one end of the second rotating shaft penetrates to the outside of the corresponding connecting plate one 71 and is connected with a cleaning component 8 for scraping the surface of the crushing roller 72. The cleaning component 8 includes a movable plate 81, a connecting strip 82 and a driving strip 83; On the outer surfaces of the two groups of connecting plates one 71, there are movably connected with movable plates 81. One end of the second rotating shaft penetrates to the outside of the corresponding connecting plate one 71 and is fixedly connected with a connecting strip 82. At one end of the outer surface of the connecting strip 82 far from the second rotating shaft, there is rotatably connected with a driving strip 83. And one end of the driving strip 83 is hinged to the corresponding movable plate 81. During the process that the crushing roller 72 moves along the filter plate 4 and rotates self, the second rotating shaft drives the connecting strip 82 to rotate forward and backward, and the driving strip 83 pulls the corresponding movable plate 81 up and down.

[0022] On both outer surfaces of the movable plate 81, there are opened with movable grooves. And inside the movable grooves, there are arranged a spring 84 and a movable column 85. One end of the movable column 85 penetrates to the outside of the movable groove and is movably connected with it. And both ends of the spring 84 are respectively fixedly connected with the movable groove and the movable column 85. Between the two groups of movable plates 81 on the same side, there is fixedly connected with an L-shaped plate 86. The movable plate 81 drives the L-shaped plate 86 to move up and down. And on one outer surface of the L-shaped plate 86, there is fixedly connected with a scraping piece 87. During the process that the scraping piece 87 moves up and down along with the L-shaped plate 86, under the action of the spring 84, it always fits with the crushing roller 72 and the rolling strips 73, and scrapes the pharmaceutical raw materials adhered to the surface of the rolling strips 73 and the crushing roller 72 during the rolling and crushing process.

[0023] Embodiment 3: As Figures 1-3As shown in the figure, the difference between this embodiment and Embodiment 1 and Embodiment 2 is that a material guiding cavity is arranged inside the crushing box 1 at a position below the filter plate 4, and a material passing component 9 for preventing the filter plate 4 and the discharge frame 3 from being blocked is arranged inside the material guiding cavity.

[0024] The material passing component 9 includes a driving wheel 91 fixedly connected to one end of a rotating rod 6 penetrating to the outside of the crushing box 1. A transmission wheel 92 is rotatably connected to a position on the outer surface of the crushing box 1 corresponding to the material guiding cavity through a connecting shaft. A conveyor belt 93 is connected in transmission between the transmission wheel 92 and the driving wheel 91. One end of the connecting shaft penetrates to the inside of the material guiding cavity and is fixedly connected to a material guiding plate 94. The transmission wheel 92 drives the connecting shaft and the material guiding plate 94 to rotate forward and backward under the transmission of the driving wheel 91 and the conveyor belt 93. Collision balls 95 are fixedly connected to positions near both sides of the upper outer surface of the material guiding plate 94. The collision balls 95 repeatedly collide with the filter plate 4, accelerating the material discharging rate of the filter plate 4, increasing the vibration frequency of the filter plate 4, and assisting the rapid discharging of the pharmaceutical raw materials.

[0025] The outer surface of the material guiding plate 94 is arc-shaped, and two groups of connecting rods 96 are hinged to a position on the lower outer surface of the material guiding plate 94 corresponding to the discharge frame 3. The bottom ends of the connecting rods 96 penetrate to the outside of the discharge frame 3 and are fixedly connected to a moving strip 97. Guide columns 98 are fixedly connected to both sides of the outer surface of the discharge frame 3. The moving strip 97 is movably connected to the guide columns 98, and moving holes are formed in positions on the outer surface of the moving strip 97 corresponding to the guide columns 98. The cross-sectional area of the moving holes is larger than the cross-sectional area of the guide columns 98. A material guiding column 99 is fixedly connected to the outer surface of the connecting rod 96; The connecting rod 96 swings left and right along with the material guiding plate 94, driving the corresponding moving strip 97 to move up and down along the corresponding guide column 98. Therefore, the connecting rod 96 can drive the material guiding column 99 to swing left and right while moving up and down, preventing blockage inside the discharge frame 3 during the material discharging process and improving the material discharging rate.

[0026] The working process and principle of the present invention are as follows: Step 1: The motor drives the rotating rod 6 to drive the crushing blades 5 to rotate 45 degrees left and right. The pharmaceutical raw materials enter the inside of the crushing box 1 through the feeding frame 2, and the crushing blades 5 perform preliminary crushing on the pharmaceutical raw materials; Step 2: The medicine after preliminary crushing falls on the surface of the filter plate 4. Fine powders and particles enter the interior of the material guiding chamber through the filter holes of the filter plate 4 and are finally discharged through the discharge frame 3 and enter the next processing procedure. During the rotation of the rotating rod 6, the first connecting plate 71 and the second connecting plate 74 drive the corresponding crushing roller 72 and the rotating roller to move along the filter plate 4 respectively. Driven by the internal rack 77, the gear 76 drives the corresponding crushing roller 72 and the rotating roller to rotate self. Therefore, the rolling bars 73 on the surface of the crushing roller 72 crush the relatively large pharmaceutical raw materials, and the rotating roller drives the cleaning brush 75 to rotate and disperse the crushed pharmaceutical raw materials to prevent the pharmaceutical raw materials from caking during the crushing process and blocking the filter holes. Step 3: During the process of the crushing roller 72 moving along the filter plate 4 and rotating self, the second rotating shaft drives the connecting bar 82 to rotate forward and backward, and the driving bar 83 pulls the corresponding movable plate 81 up and down. Therefore, the movable plate 81 drives the L-shaped plate 86 to move up and down. During the process of the scraping piece 87 moving up and down with the L-shaped plate 86, it always fits with the crushing roller 72 and the rolling bar 73 under the action of the spring 84. Therefore, it can scrape the pharmaceutical raw materials adhered to the surface of the rolling bar 73 and the crushing roller 72 during the rolling and crushing process, preventing the pharmaceutical raw materials from caking on the surfaces of the rolling bar 73 and the crushing roller 72 due to excessive rolling during the long-term crushing process and improving the crushing strength. Step 4: The pharmaceutical raw materials that have undergone double processing of crushing and grinding enter the surface of the material guiding plate 94 through the filter plate 4. Driven by the driving wheel 91 and the conveyor belt 93, the driving wheel 92 drives the connecting shaft and the material guiding plate 94 to rotate forward and backward. During the process of the material guiding plate 94 rotating forward and backward, the collision balls 95 repeatedly collide with the filter plate 4, accelerating the blanking rate of the filter plate 4 and improving the uniformity of the distribution of the pharmaceutical raw materials on the surface of the filter plate 4. The pharmaceutical raw materials are finally discharged through the discharge frame 3. Step 5: The connecting rod 96 swings left and right with the material guiding plate 94 and drives the corresponding moving bar 97 to move up and down along the corresponding guiding column 98. Therefore, while moving up and down, the connecting rod 96 can also drive the material guiding column 99 to swing left and right, preventing blockage inside the discharge frame 3 during the blanking process and improving the blanking rate.

[0027] The above is only a preferred specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, according to the technical solution and inventive concept of the present invention, makes equivalent substitutions or changes, and should be covered by the protection scope of the present invention.

Claims

1. A pulverizing device suitable for carbamazepine tablets pharmaceutical raw materials, comprising a pulverizing box (1), characterized in that: The top end of the outer surface of the crushing box (1) is fixedly connected to a feed frame (2), and the lower end of the outer surface of the crushing box (1) is fixedly connected to a discharge frame (3); The crushing box (1) is fixedly connected to a filter plate (4) inside, and a motor is provided near the top of an outer surface of one side of the crushing box (1), the output end of the motor passes through the inside of the crushing box (1) and is fixedly connected to a rotating rod (6), a plurality of groups of crushing blades (5) are fixedly connected to the outer surface of the rotating rod (6), and a crushing mechanism (7) is provided between the rotating rod (6) and the filter plate (4); A material guide cavity is arranged inside the pulverizing box (1) at a position below the filter plate (4), and a material passing component (9) is arranged inside the material guide cavity to prevent the filter plate (4) and the discharge frame (3) from being blocked.

2. A comminution device suitable for carbamazepine tablets pharmaceutical raw materials according to claim 1, characterized in that: The pulverizing mechanism (7) comprises a connecting plate 1 (71), a pulverizing roller (72), a rolling strip (73) and a connecting plate 2 (74); the outer surface of the rotating rod (6) is fixedly connected to the connecting plate 1 (71) at positions near both ends; the pulverizing roller (72) is rotatably connected between two groups of the connecting plates 1 (71); and the outer surface of the pulverizing roller (72) is fixedly connected to a plurality of groups of rolling strips (73) at equal distances; the outer surface of the rolling strip (73) is in contact with the outer surface of the filter plate (4); the outer surface of the rotating rod (6) is fixedly connected to the connecting plate 2 (74) at positions on both sides of the connecting plate 1 (71) near both ends; a rotating roller is fixedly connected between the two corresponding groups of the connecting plates 2 (74); and a cleaning brush (75) is fixedly connected to the outer surface of the rotating roller.

3. A comminution device suitable for carbamazepine tablets pharmaceutical raw materials according to claim 2, characterized in that: One end of the crushing roller (72) and the rotating roller are both fixedly connected to a rotating shaft 1, and one end of the rotating shaft 1 passes through the outside of the corresponding connecting plate 1 (71) and the connecting plate 2 (74) and is fixedly connected to a gear (76), and an inner rack (77) is fixedly connected to the inner surface of the crushing box (1) at a position corresponding to the gear (76), the inner surface of the inner rack (77) is arc-shaped, and the gear (76) meshes with the inner rack (77), and the outer surface of the crushing roller (72) is fixedly connected to a rotating shaft 2 at one end away from the rotating shaft 1, and one end of the rotating shaft 2 passes through the outside of the corresponding connecting plate 1 (71) and is connected to a cleaning component (8) for scraping the surface of the crushing roller (72).

4. A comminution device suitable for carbamazepine tablets pharmaceutical raw materials according to claim 3, characterized in that: The cleaning assembly (8) comprises a movable plate (81), a connecting strip (82) and a driving strip (83); the outer surfaces of the two groups of connecting plates (71) are movably connected to the movable plate (81), one end of the rotating shaft (2) passes through the outside of the corresponding connecting plate (71) and is fixedly connected to the connecting strip (82), the outer surface of the connecting strip (82) is rotatably connected to the driving strip (83) at one end away from the rotating shaft (2), and one end of the driving strip (83) is hinged to the corresponding movable plate (81).

5. A pulverizing device suitable for carbamazepine tablets pharmaceutical raw materials according to claim 4, characterized in that: Both sides of the movable plate (81) are provided with movable grooves on their outer surfaces, and a spring (84) and a movable column (85) are arranged inside the movable grooves, one end of the movable column (85) passes through the outside of the movable groove and is movably connected thereto, and both ends of the spring (84) are respectively fixedly connected to the movable groove and the movable column (85), an L-shaped plate (86) is fixedly connected between the two groups of movable plates (81) located on the same side, and a scraper (87) is fixedly connected to the outer surface of one side of the L-shaped plate (86).

6. A comminution device suitable for carbamazepine tablets pharmaceutical raw materials according to claim 1, characterized in that: The material passing assembly (9) comprises a driving wheel (91) having one end of a rotating rod (6) extending through the outside of the crushing box (1) and fixedly connected thereto; a transmission wheel (92) is rotatably connected to a position of the outer surface of the crushing box (1) corresponding to the material guide cavity via a connecting shaft; a conveyor belt (93) is transmission-connected between the transmission wheel (92) and the driving wheel (91); one end of the connecting shaft extends through the inside of the material guide cavity and is fixedly connected thereto a material guide plate (94); and collision balls (95) are fixedly connected to the outer surface of the upper end of the material guide plate (94) near both sides.

7. A comminution device suitable for carbamazepine tablets pharmaceutical raw materials according to claim 6, characterized in that: The outer surface of the guide plate (94) is arc-shaped, and two groups of connecting rods (96) are hingedly connected to the outer surface of the lower end of the guide plate (94) at a position corresponding to the discharge frame (3), and the bottom ends of the connecting rods (96) penetrate to the outside of the discharge frame (3) and are fixedly connected to the moving bars (97).

8. A pulverizing device suitable for carbamazepine tablets pharmaceutical raw materials according to claim 6, characterized in that: Guide columns (98) are fixedly connected to both sides of the outer surface of the discharge frame (3); the movable bar (97) is movably connected to the guide column (98); and movable holes are opened at positions on the outer surface of the movable bar (97) corresponding to the guide column (98); the cross-sectional area of ​​the movable hole is larger than the cross-sectional area of ​​the guide column (98); and the outer surface of the connecting rod (96) is fixedly connected to a material guide column (99).

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