Reagent extraction device, reagent extraction method and sample analyzer

Abstract

The present application discloses a reagent extraction device, a reagent extraction method and a sample analyzer, the reagent extraction device comprising: a reagent module for storing a reagent; the sampling assembly is used for collecting the reagent through the reagent needle; the liquid level detection module is used for detecting the liquid level height of the reagent; the control module is used for obtaining the initial liquid level height; determining a first height and a second height based on the initial liquid level height; the first height is larger than the initial liquid level, and the second height is smaller than the initial liquid level; controlling the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height; in response to the condition that the third height is not smaller than the second height and not larger than the first height, the needle head of the reagent needle is controlled to move to the position below the third height for reagent extraction, the initial liquid level height is updated based on the third height, and the reliability of reagent extraction is improved.

Description

Technical Field

[0001] This application relates to the field of detection technology, and particularly to a reagent extraction device, a reagent extraction method, and a sample analyzer. Background Art

[0002] In the prior art, generally, a reagent needle is controlled to extract a reagent from a reagent module (such as a dye solution bottle or other types of reagent bottles), and a liquid level detection module is used to determine the liquid level height in the reagent module to determine the sampling height of the reagent needle.

[0003] The defect of the prior art is that the liquid level detection module can usually be a device that detects the liquid level height in the reagent module by using a pressure detection method, an optoelectronic detection method, a radio frequency detection method, an impedance detection method, or a capacitance detection method. However, the liquid level detection module also has the possibility of failure. If only relying on the liquid level detection module for liquid level detection, it is easy to cause the reagent needle to fail to extract the corresponding reagent smoothly when the liquid level detection module makes a mistake, such as the phenomenon of air aspiration, resulting in poor reliability of reagent extraction. Summary of the Invention

[0004] The main technical problem to be solved by this application is how to improve the reliability of reagent extraction.

[0005] To solve the above technical problem, the first technical solution adopted by this application is: a reagent extraction device, including: a reagent module for storing a reagent; a sampling component for collecting the reagent through a reagent needle; a liquid level detection module for detecting the liquid level height of the reagent; a control module for: obtaining an initial liquid level height; determining a first height and a second height based on the initial liquid level height, the first height being greater than the initial liquid level height, and the second height being less than the initial liquid level height; controlling the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height; in response to the third height being not less than the second height and not greater than the first height, controlling the needle of the reagent needle to move to a position below the third height for reagent extraction, and updating the initial liquid level height based on the third height.

[0006] Among them, updating the initial liquid level height based on the third height includes: in response to the third height being not greater than the sum of the initial liquid level height and a preset error threshold, updating the initial liquid level height to the difference between the third height and the reagent extraction amount height.

[0007] Among them, updating the initial liquid level height based on the third height further includes: in response to the third height being greater than the sum of the initial liquid level height and the preset error threshold, updating the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0008] Among them, after the control liquid level detection module detects the liquid level height of the reagent in the reagent module and obtains the third height, the control module is further configured to: in response to the third height being greater than the first height, control the needle of the reagent needle to move to a position below the second height for reagent extraction, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0009] Among them, in response to the third height being greater than the first height, controlling the needle of the reagent needle to move to a position below the second height for reagent extraction includes: in response to the third height being greater than the first height, controlling the liquid level detection module to re-detect the liquid level height of the reagent in the reagent module and update the third height; in response to the updated third height being greater than the first height, controlling the needle of the reagent needle to move to a position below the second height for reagent extraction.

[0010] Among them, the control module is further configured to: in response to the reagent needle not detecting the reagent when it moves down to the second height, control the needle of the reagent needle to move to a position below the second height for reagent extraction, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0011] Among them, the liquid level detection module is configured to detect whether the needle of the reagent needle touches the reagent to obtain a touch detection result, and determine the liquid level height of the reagent based on the touch detection result; controlling the liquid level detection module to detect the liquid level height of the reagent in the reagent module and obtain the third height includes: in response to the reagent needle not detecting the reagent when it moves down to the second height, controlling the reagent needle to continue moving down until the liquid level detection module detects the reagent to obtain the third height; the control module is further configured to: if the reagent is still not detected when the reagent needle reaches the preset lowest liquid level, output an alarm indication for indicating that the liquid volume is empty; if the liquid level detection module detects the reagent before the reagent needle reaches the preset lowest liquid level and obtains the third height, control the reagent needle to move to a position below the third height for reagent extraction, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0012] Among them, determining the first height and the second height based on the initial liquid level height includes: adding the reagent extraction height to the initial liquid level height to obtain a target sum value; multiplying the target sum value by a first preset ratio to obtain the first height; and / or, subtracting the reagent extraction height from the initial liquid level height to obtain a target difference value; multiplying the target difference value by a second preset ratio to obtain the second height; both the first preset ratio and the second preset ratio are greater than 0 and not greater than 1.

[0013] To solve the above technical problems, the second technical solution adopted in this application is: a reagent extraction method applied to the above reagent extraction device; the reagent extraction method includes: obtaining the initial liquid level height; determining a first height and a second height based on the initial liquid level height; the first height is greater than the initial liquid level height, and the second height is less than the initial liquid level height; controlling the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height; in response to the third height being not less than the second height and not greater than the first height, controlling the needle of the reagent needle to move to a position below the third height to extract the reagent, and updating the initial liquid level height based on the third height.

[0014] To solve the above technical problems, the third technical solution adopted in this application is: a sample analyzer including the above reagent extraction device.

[0015] The beneficial effects of this application are as follows: Different from the prior art, in the technical solution of this application, the reagent extraction device includes a reagent module, a sampling assembly, a liquid level detection module, and a control module. The control module is used for: obtaining the initial liquid level height, determining a first height and a second height based on the initial liquid level height, controlling the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height, and in response to the third height being not less than the second height and not greater than the first height, controlling the needle of the reagent needle to move to a position below the third height to extract the reagent, and updating the initial liquid level height based on the third height. Based on the above method, it can be considered that the detection result obtained by the liquid level detection module is credible only when it is judged that the third height obtained by the liquid level detection module is between the first height and the second height. The reagent needle can be controlled to move below the third height to extract the reagent, and the initial liquid level height can be updated based on the third height for use in the next reagent extraction, thereby improving the accuracy of the initial liquid level height and the possibility that the reagent needle can pick up the required reagent, and further improving the reliability of reagent extraction. Description of the Drawings

[0016] To more clearly illustrate the technical solutions in the embodiments of the present invention, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the following drawings are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0017] Figure 1 It is a schematic structural diagram of an embodiment of the reagent extraction device of this application;

[0018] Figure 2 It is a schematic flowchart of an embodiment of the reagent extraction method of this application;

[0019] Figure 3 It is a schematic structural diagram of an embodiment of the sample analyzer of the present application.

[0020] Among them: reagent module 11, sampling component 12, liquid level detection module 13, control module 14, sample analyzer 20, reagent extraction device 21. Specific embodiments

[0021] The following will further describe the present application in detail in conjunction with the accompanying drawings and embodiments. It should be specifically noted that the following embodiments are only used to illustrate the present application, but do not limit the scope of the present application. Similarly, the following embodiments are only some embodiments of the present application rather than all embodiments. All other embodiments obtained by those of ordinary skill in the art without creative work fall within the scope of protection of the present application.

[0022] Referring to "embodiments" herein means that the specific features, structures, or characteristics described in connection with the embodiments may be included in at least one embodiment of the present application. The phrase appears in various places in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments. Those skilled in the art will explicitly and implicitly understand that the embodiments described herein may be combined with other embodiments.

[0023] In the description of the present application, it should be noted that unless otherwise clearly specified and limited, the terms "installed", "set", "connected", and "connected" should be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or an integral connection; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium. For those of ordinary skill in the art, the specific meaning of the above terms in the present application can be understood according to specific circumstances.

[0024] The present application first proposes a reagent extraction device. Refer to Figure 1 , Figure 1 It is a schematic structural diagram of an embodiment of the reagent extraction device of the present application. As Figure 1 shown, the reagent extraction device includes a reagent module 11, a sampling component 12, a liquid level detection module 13, and a control module 14.

[0025] The reagent module 11 is used to store reagents. Among them, the reagent module 11 may specifically be a reagent bottle or other types of containers for storing reagents. The reagent may specifically be a staining solution or other types of reagents that can be used for sample detection, which is not limited here.

[0026] The sampling assembly 12 is used to collect reagents through the reagent needle 121. Among them, the sampling assembly 12 may have a sampling motor and a reagent needle 121. The sampling motor can be used to control the movement of the reagent needle 121. For example, it can control the needle tip of the reagent needle 121 to enter or leave the reagent in the reagent module 11.

[0027] The liquid level detection module 13 is used to detect the liquid level height of the reagent. Among them, the liquid level detection module 13 can specifically be a module that detects the liquid level based on the pressure detection method. The specific method is to use a pressure sensor to sense the pressure change in the reagent needle 121 or the pipeline connected to the reagent needle 121, so as to determine whether the needle tip of the reagent needle 121 touches the liquid surface, and combine the initial height of the needle tip of the reagent needle 121 and the height of the needle tip when touching the liquid surface to determine the liquid level height of the reagent.

[0028] The liquid level detection module 13 can specifically also be a module that detects the liquid level by using the photoelectric detection method. The specific method is to set a photoelectric sensor near the needle tip on the reagent needle 121, so as to determine whether the needle tip of the reagent needle 121 touches the liquid surface by sensing the change degree of the reflected light, and combine the initial height of the needle tip of the reagent needle 121 and the height of the needle tip when touching the liquid surface to determine the liquid level height of the reagent.

[0029] The liquid level detection module 13 can specifically also be a module that detects the liquid level by using the radio frequency detection method. The specific method is to set a radio frequency signal transmitter and a receiver near the needle tip on the reagent needle 121, so as to determine whether the needle tip of the reagent needle 121 touches the liquid surface by the change degree of the received radio frequency signal, and combine the initial height of the needle tip of the reagent needle 121 and the height of the needle tip when touching the liquid surface to determine the liquid level height of the reagent.

[0030] The liquid level detection module 13 can specifically also be a module that detects the liquid level by using the impedance detection method. The specific method is that the reagent needle has two interconnected needle tips. By determining the impedance change between the two needle tips, it is determined whether the needle tip of the reagent needle 121 touches the liquid surface, and combine the initial height of the needle tip of the reagent needle 121 and the height of the needle tip when touching the liquid surface to determine the liquid level height of the reagent.

[0031] The liquid level detection module 13 can specifically also be a module that detects the liquid level by using the capacitance detection method. The specific method is to use the reagent needle 121 as a variable capacitor, perform capacitance detection on this variable capacitor, and determine whether the needle tip of the reagent needle 121 touches the liquid surface through the capacitance change, and combine the initial height of the needle tip of the reagent needle 121 and the height of the needle tip when touching the liquid surface to determine the liquid level height of the reagent.

[0032] In one example, if the liquid level detection module 13 is a module that detects the liquid level by using the capacitance detection method, then the liquid level detection module 13 may include a detection circuit, a judgment circuit, and a first control circuit.

[0033] The detection circuit is connected to a reagent needle, which is a capacitive reagent needle. The detection circuit is configured to input a detection signal and output a target voltage signal. Among them, the detection signal is determined by the contact situation between the capacitive reagent needle and the liquid level.

[0034] The judgment circuit is connected to the detection circuit. The judgment circuit is configured to input the target voltage signal and a reference voltage signal, and is used to judge the magnitude relationship between the target voltage signal and the reference voltage signal, and output a judgment result signal.

[0035] The first control circuit is connected to the judgment circuit. The first control circuit is configured to control the reagent needle to perform sampling according to the judgment result signal.

[0036] Based on the above method, the detection signal used to characterize the contact situation between the capacitive reagent needle and the liquid level can be further processed to determine whether the capacitive reagent needle touches the liquid level, so as to determine the liquid level height of the reagent by combining the initial height of the needle tip of the reagent needle 121 and the height of the needle tip when touching the liquid level, realizing liquid level detection.

[0037] The control module 14 is used for:

[0038] Obtain the initial liquid level height. Among them, when the current reagent module 11 has not performed reagent extraction, the initial liquid level height can specifically be the theoretical initial height of the reagent in the reagent module 11. When the current reagent module 11 has performed reagent extraction, the initial liquid level height can specifically be the initial liquid level height updated and determined during the previous reagent extraction of the reagent module 11.

[0039] Based on the initial liquid level height, determine a first height and a second height. Among them, the first height is greater than the initial liquid level height, and the second height is less than the initial liquid level height. That is, the order from low to high is the second height - the initial liquid level height - the first height.

[0040] In one example, the first height and the second height can be obtained based on the initial liquid level height and a preset difference. That is, the first height is determined based on the sum of the initial liquid level height and the preset difference, and the second height can be determined based on the difference between the initial liquid level height and the preset difference. This preset difference can be set according to actual application requirements and is not limited here. Optionally, the difference between the initial liquid level height and the first height and the difference between the initial liquid level height and the second height can also be different.

[0041] In one example, the first height can be determined based on the sum of the initial liquid level height and the reagent extraction height, and the second height can be determined based on the difference between the initial liquid level height and the extracted reagent height. Specifically, the reagent extraction height is the expected height by which the reagent liquid level will decrease after the reagent extraction in this reagent extraction, and this height is specifically associated with the amount of reagent to be extracted in this reagent extraction and the shape characteristics of the reagent bottle. Optionally, at least one of the difference between the initial liquid level height and the first height and the difference between the initial liquid level height and the second height is less than the reagent extraction height. In other examples, the first height and the second height corresponding to the initial liquid level height can also be determined in other ways, which are not limited here.

[0042] Control the liquid level detection module 13 to detect the liquid level height of the reagent in the reagent module 11, and obtain the third height.

[0043] Among them, the reagent needle 121 can be controlled to move in the direction of the reagent, and the liquid level detection module 13 can be used to determine whether the reagent needle 121 touches the liquid level, so as to determine the liquid level height.

[0044] In response to the third height being not less than the second height and not greater than the first height, control the needle of the reagent needle 121 to move to a position below the third height for reagent extraction, and update the initial liquid level height based on the third height.

[0045] Among them, if when the needle of the reagent needle 121 moves to the area between the second height and the first height, the reagent needle 121 touches the liquid level and thus obtains the third height, it can be considered that the value of this third height is within the expected range, that is, the credibility of this third height is relatively high. Therefore, at this time, the needle of the reagent needle 121 can be controlled to move to a position below the third height for reagent extraction, to achieve this reagent extraction, and the initial liquid level height can be updated based on the third height, so as to provide a relatively accurate initial liquid level height for the next reagent extraction and improve the success rate of the next reagent extraction. In summary, the reliability of reagent extraction is improved.

[0046] It should be noted that, in one example, the position below the above-mentioned third height can specifically be a position that changes as the liquid level of the reagent drops. For example, a position below the above-mentioned third height and always at a preset height threshold from the liquid level of the reagent, or other positions below the above-mentioned third height and always below the liquid level of the reagent, which are not limited here.

[0047] In other examples, the position below the above-mentioned third height can specifically also be the position at the height obtained by subtracting the preset height threshold from the third height and then subtracting the reagent extraction height. The preset height threshold can be specifically determined according to actual needs, which are not limited here.

[0048] Different from the prior art, in the technical solution of this application, the reagent extraction device includes a reagent module, a sampling component, a liquid level detection module, and a control module. The control module is used to: obtain the initial liquid level height, determine a first height and a second height based on the initial liquid level height, control the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height. In response to the third height being not less than the second height and not greater than the first height, control the needle of the reagent needle to move to a position below the third height to extract the reagent, and update the initial liquid level height based on the third height. Based on the above method, it can be considered that the detection result obtained by the liquid level detection module is credible only when it is judged that the third height obtained by the liquid level detection module is between the first height and the second height. The reagent needle can be controlled to move below the third height to extract the reagent, and the initial liquid level height can be updated based on the third height for use in the next reagent extraction, thereby improving the accuracy of the initial liquid level height and the possibility that the reagent needle can extract the required reagent, and further improving the reliability of reagent extraction.

[0049] In one embodiment, updating the initial liquid level height based on the third height includes:

[0050] In response to the third height being not greater than the sum of the initial liquid level height and the preset error threshold, update the initial liquid level height to the difference between the third height and the reagent extraction height.

[0051] Specifically, when it is detected that the third height is not greater than the sum of the initial liquid level height and the preset error threshold, it can be considered that the credibility of the third height obtained by detecting the liquid level height through the liquid level detection module 13 at this time is relatively high and relatively accurate. Therefore, at this time, the initial liquid level height can be updated to the difference between the third height and the reagent extraction height, that is, the corresponding difference obtained by subtracting the height by which the reagent liquid level will drop during this reagent extraction from the third height detected by the liquid level detection module 13 is used as the new initial liquid level height to complete the update.

[0052] In one example, the preset error threshold is less than the difference between the initial liquid level height and the first height, and / or the preset error threshold is less than the difference between the initial liquid level height and the second height.

[0053] Based on the above method, when the third height is not greater than the sum of the initial liquid level height and the preset error threshold, it can be considered that the accuracy of the third height detected this time is relatively high, and the initial liquid level height is updated based on this, improving the reliability of reagent extraction.

[0054] Optionally, updating the initial liquid level height based on the third height further includes:

[0055] In response to the third height being greater than the sum of the initial liquid level height and the preset error threshold, update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0056] Specifically, under normal circumstances, the third height should generally be greater than the initial liquid level height, and even if there is an error, it will not be too large. Therefore, when it is detected that the third height is greater than the sum of the initial liquid level height and the preset error threshold, it can be considered that the accuracy of the third height detected this time is relatively low, and it may be affected by bubbles on the reagent surface and other factors, resulting in inaccurate detection. Therefore, at this time, the third height obtained by the liquid level detection module 13 this time can be ignored, and instead, the corresponding difference is obtained by subtracting the reagent extraction height from the initial liquid level height, and the initial liquid level height is updated to this difference, so as to provide a relatively accurate initial liquid level height for the next reagent extraction, improve the success rate of the next reagent extraction, reduce the possibility of reagent extraction errors caused by updating the initial liquid level height with inaccurate third height, and improve the reliability of reagent extraction.

[0057] In one embodiment, after controlling the liquid level detection module 13 to detect the liquid level height of the reagent in the reagent module 11 and obtain the third height, the control module 14 is further configured to:

[0058] In response to the third height being greater than the first height, control the needle of the reagent needle 121 to move to a position below the second height for reagent extraction, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0059] Specifically, when the liquid level is detected at a position higher than the first height, it is considered that the detection result of the liquid level detection module 13 this time may be incorrect, and it may be affected by bubbles on the reagent surface and other factors, resulting in inaccurate detection. To ensure the successful progress of reagent extraction, the needle of the reagent needle 121 can be controlled to move to a position below the lowest second height for reagent extraction, reducing the possibility of reagent extraction failure caused by reagent extraction based on inaccurate third height. At the same time, at this time, the third height obtained by the liquid level detection module 13 this time can be ignored, and instead, the corresponding difference is obtained by subtracting the reagent extraction height from the initial liquid level height, and the initial liquid level height is updated to this difference, so as to provide a relatively accurate initial liquid level height for the next reagent extraction, improve the success rate of the next reagent extraction, and improve the reliability of reagent extraction. The technical solution of this application combines the calculated height range with the liquid level detection function of the hardware module, which can reduce situations such as false alarms caused by other environmental factors interfering with liquid level detection, the need for secondary detection, and the impact of false alarms on test results, and improve the reliability of liquid level detection and reagent extraction.

[0060] It should be noted that the position below the above-mentioned second height can specifically be the position at the height obtained by subtracting the preset height threshold from the second height and then subtracting the reagent extraction height. The preset height threshold can be determined according to actual needs and is not limited here.

[0061] In addition, when it is detected that the third height is greater than the first height, it is also possible to prompt misdetection of the liquid level detection or prompt premature liquid contact. The maintenance personnel can check according to the prompt, or check only when the number of prompts is greater than the preset number threshold.

[0062] Optionally, in response to the third height being greater than the first height, control the needle of the reagent needle 121 to move to a position below the second height for reagent extraction, including:

[0063] In response to the third height being greater than the first height, control the liquid level detection module 13 to re-detect the liquid level height of the reagent in the reagent module 11 and update the third height.

[0064] In response to the updated third height being greater than the first height, control the needle of the reagent needle 121 to move to a position below the second height for reagent extraction.

[0065] Specifically, when it is detected that the third height is greater than the first height, it can be considered that the detection result of the liquid level detection module 13 this time may be incorrect. Therefore, the liquid level detection module 13 can be controlled to re-detect the liquid level height.

[0066] If the result obtained from re-detecting the liquid level height is that the third height is not greater than the first height and not less than the second height, then control the needle of the reagent needle 121 to move to a position below the third height for reagent extraction, and update the initial liquid level height based on the third height.

[0067] If the result obtained from re-detecting the liquid level height is that no reagent is detected when the reagent needle moves down to the second height, then control the needle of the reagent needle 121 to move to a position below the second height for reagent extraction, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0068] If the result obtained from re-detecting the liquid level height is still that the third height is greater than the first height, then it can be finally determined that the detection result of the liquid level detection module 13 this time may be incorrect, and it may be affected by bubbles on the surface of the reagent and other factors, resulting in inaccurate detection. That is, based on more than two repeated detections, the possibility that the detection result of the liquid level detection module 13 this time is incorrect is relatively high.

[0069] At this time, the needle of the reagent needle 121 can be controlled to move to a position below the second height with the lowest height for reagent extraction, reducing the possibility of reagent extraction failure caused by reagent extraction based on an inaccurate third height, and improving the reliability of reagent extraction.

[0070] In one embodiment, the control module 14 is further configured to:

[0071] In response to the reagent needle not detecting the reagent when moving down to the second height, control the needle of the reagent needle 121 to move to a position below the second height for reagent extraction, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0072] Specifically, when the reagent needle moves down to the second height and the reagent is not detected, it can be considered that the detection result of the liquid level detection module 13 this time may be incorrect. To ensure the successful progress of reagent extraction, the needle of the reagent needle 121 can be controlled to move to a position below the second height with the lowest height for reagent extraction, reducing the possibility of reagent extraction failure caused by reagent extraction based on an inaccurate third height. At the same time, the third height obtained by the liquid level detection module 13 this time can be ignored, and instead, the corresponding difference is obtained by subtracting the reagent extraction height from the initial liquid level height, and the initial liquid level height is updated to this difference to provide a relatively accurate initial liquid level height for the next reagent extraction, improving the success rate of the next reagent extraction and the reliability of reagent extraction.

[0073] It should be noted that the position below the second height specifically can be the position at the height obtained by subtracting the preset height threshold from the second height and then subtracting the reagent extraction height. The preset height threshold can be determined according to actual needs and is not limited here.

[0074] In addition, when it is detected that the third height is less than the second height, it can also be prompted that the reagent stock is insufficient, and the maintenance personnel can check according to the prompt, or check only when the number of prompts is greater than the preset number threshold.

[0075] In one embodiment, the liquid level detection module 13 is configured to detect whether the needle of the reagent needle 121 touches the reagent, obtain a touch detection result, and determine the liquid level height of the reagent based on the touch detection result.

[0076] Controlling the liquid level detection module 13 to detect the liquid level height of the reagent in the reagent module 11 to obtain a third height includes:

[0077] In response to the reagent needle 121 not detecting the reagent when moving down to the second height, control the reagent needle 121 to continue moving down until the liquid level detection module 13 detects the reagent to obtain the third height before reaching the preset lowest liquid level.

[0078] The control module is further configured to:

[0079] If no reagent is detected when the reagent needle 121 reaches the preset lowest liquid level, an alarm indication for indicating an empty liquid volume is output.

[0080] If the liquid level detection module 13 detects the reagent before the reagent needle 121 reaches the preset lowest liquid level and obtains a third height, the reagent needle 121 is controlled to move to a position below the third height to extract the reagent, and the initial liquid level height is updated to the difference between the initial liquid level height and the reagent extraction height.

[0081] Specifically, when the needle of the reagent needle 121 moves to the second height, if the liquid level detection module 13 has not detected that the needle of the reagent needle 121 touches the liquid level of the reagent, it can be determined that the third height is below the second height. At this time, the reagent needle 121 can be controlled to continue moving towards the preset lowest liquid level of the accommodation cavity for storing the reagent in the reagent module 11.

[0082] If it is detected that the reagent needle 121 touches the reagent before the reagent needle 121 moves to the preset lowest liquid level, the third height is determined, and the needle of the reagent needle 121 is controlled to move to a position below the third height to extract the reagent, and the initial liquid level height is updated to the difference between the initial liquid level height and the reagent extraction height.

[0083] If the reagent needle 121 does not touch the reagent when the reagent needle 121 moves to the preset lowest liquid level, a prompt that the reagent is empty is output, and the maintenance personnel can check according to the prompt, or check only when the number of prompts is greater than the preset number threshold.

[0084] It should be noted that the height value of the preset lowest liquid level can be specifically determined according to the reagent extraction height corresponding to the current reagent extraction, and is not limited here. In one example, the preset lowest liquid level may not be less than the reagent extraction height.

[0085] In one embodiment, determining the first height and the second height based on the initial liquid level height and the reagent extraction height includes:

[0086] Adding the initial liquid level height and the reagent extraction height to obtain a target sum value.

[0087] Multiplying the target sum value by a first preset ratio to obtain the first height.

[0088] And / or,

[0089] Subtracting the reagent extraction height from the initial liquid level height to obtain a target difference value.

[0090] Multiplying the target difference value by a second preset ratio to obtain the second height.

[0091] Wherein, both the first preset ratio and the second preset ratio are greater than 0 and not greater than 1.

[0092] Specifically, the above-mentioned first preset ratio can specifically be 70% or 80% or 90% or 100% or other ratios, and the above-mentioned second preset ratio can specifically be 70% or 80% or 90% or 100% or other ratios, which can be specifically determined according to actual needs and are not limited herein.

[0093] Based on the above method, by presetting corresponding first and second preset ratios, the regulation and control of the determined first height and second height can be achieved, so that the first height and second height actually determined based on the initial liquid level height are more in line with expectations, thereby improving the accuracy of the initial liquid level height updated based on the third height when the third height is not less than the second height and not greater than the first height subsequently, and improving the reliability of subsequent reagent extraction.

[0094] This application proposes a reagent extraction method, which can be applied to the reagent extraction device described in any of the foregoing embodiments. Refer to Figure 2 , Figure 2 is a schematic flowchart of an embodiment of the reagent extraction method of this application. As Figure 2 shown, the reagent extraction method includes:

[0095] Step S11: Obtain the initial liquid level height.

[0096] Step S12: Based on the initial liquid level height, determine a first height and a second height. Among them, the first height is greater than the initial liquid level height, and the second height is less than the initial liquid level height.

[0097] Step S13: Control the liquid level detection module 13 to detect the liquid level height of the reagent in the reagent module 11 to obtain a third height.

[0098] Step S14: In response to the third height being not less than the second height and not greater than the first height, control the needle of the reagent needle 121 to move to a position below the third height for reagent extraction, and update the initial liquid level height based on the third height.

[0099] Different from the prior art, in the technical solution of the present application, the reagent extraction device includes a reagent module, a sampling component, a liquid level detection module, and a control module. The control module is configured to: obtain the initial liquid level height, determine a first height and a second height based on the initial liquid level height, control the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height, and in response to the third height being not less than the second height and not greater than the first height, control the needle of the reagent needle to move to a position below the third height for reagent extraction, and update the initial liquid level height based on the third height. Based on the above method, it can be considered that the detection result obtained by the liquid level detection module is credible only when it is judged that the third height obtained by the liquid level detection module is between the first height and the second height. The reagent needle can be controlled to move below the third height for reagent extraction, and the initial liquid level height can be updated based on the third height for use in the next reagent extraction, thereby improving the accuracy of the initial liquid level height and the possibility that the reagent needle can extract the required reagent, and further improving the reliability of reagent extraction.

[0100] In one embodiment, as Figure 2 shown, after step S13, the reagent extraction method may further include:

[0101] Step S15: In response to the third height being greater than the first height, control the needle of the reagent needle 121 to move to a position below the second height for reagent extraction, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0102] In one embodiment, as Figure 2 shown, after step S13, the reagent extraction method may further include:

[0103] Step S16: In response to the reagent needle not detecting the reagent when it moves down to the second height, control the needle of the reagent needle 121 to move to a position below the second height for reagent extraction, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0104] It should be noted that the reagent extraction method may further include the steps performed by the control module 14 of the reagent extraction device described in any of the foregoing embodiments, which will not be elaborated herein.

[0105] The present application provides a sample analyzer. Refer to Figure 3 , Figure 3 which is a schematic structural diagram of an embodiment of the sample analyzer of the present application. As Figure 3 shown, the sample analyzer 20 includes a reagent extraction device 21, and the reagent extraction device 21 may specifically be the reagent extraction device described in any of the foregoing embodiments, which will not be elaborated herein.

[0106] Different from the prior art, in the technical solution of the present application, the reagent extraction device includes a reagent module, a sampling assembly, a liquid level detection module, and a control module. The control module is configured to: obtain an initial liquid level height, determine a first height and a second height based on the initial liquid level height, control the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height, and in response to the third height being not less than the second height and not greater than the first height, control the needle of the reagent needle to move to a position below the third height to extract the reagent, and update the initial liquid level height based on the third height. Based on the above method, it can be considered that the detection result obtained by the liquid level detection module is credible only when it is determined that the third height obtained by the liquid level detection module is between the first height and the second height. The reagent needle can be controlled to move below the third height to extract the reagent, and the initial liquid level height can be updated based on the third height for use in the next reagent extraction, thereby improving the accuracy of the initial liquid level height and the possibility that the reagent needle can extract the required reagent, and further improving the reliability of reagent extraction.

[0107] In the description of the present application, the descriptions referring to terms such as "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. mean that the specific features, structures, materials, or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described can be combined in a suitable manner in any one or more embodiments or examples. In addition, without contradiction, those skilled in the art can combine and combine the different embodiments or examples described in this specification and the features of different embodiments or examples.

[0108] In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" can explicitly or implicitly include at least one of the features. In the description of the present application, "a plurality of" means at least two, such as two, three, etc., unless otherwise specifically defined.

[0109] Any process or method description in the flowchart or described in other ways herein can be understood as representing a module, segment, or part of code including one or more executable instructions for implementing a specific logical function or process. The scope of the preferred embodiments of the present application includes additional implementations, where the functions can be executed in a substantially simultaneous manner or in a reverse order according to the involved functions, rather than in the order shown or discussed, which should be understood by those skilled in the art of the embodiments of the present application.

[0110] The logic and / or steps represented in the flowchart or otherwise described herein, for example, can be considered as a definite sequence list of executable instructions for implementing logical functions, and can be embodied specifically in any computer-readable medium for use by an instruction execution system, apparatus, or device (which can be a personal computer, server, network device, or other system that can fetch instructions from the instruction execution system, apparatus, or device and execute the instructions), or used in conjunction with these instruction execution systems, apparatuses, or devices. For the purposes of this specification, a "computer-readable medium" can be any device that can contain, store, communicate, propagate, or transport a program for use by or in conjunction with an instruction execution system, apparatus, or device. More specific examples (a non-exhaustive list) of computer-readable media include the following: an electrical connection portion with one or more wirings (electronic device), a portable computer diskette (magnetic device), a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber device, and a portable compact disc read-only memory (CDROM). Additionally, the computer-readable medium can even be paper or other suitable media on which the program can be printed, because the program can be obtained electronically, for example, by optically scanning the paper or other media, followed by editing, interpretation, or otherwise processing as appropriate, and then storing it in a computer memory.

[0111] The above description is only for the implementation modes of this application, and does not limit the patent scope of this application. Any equivalent structure or equivalent process transformation made by using the content of the specification and drawings of this application, or directly or indirectly applied in other related technical fields, shall be equally included in the patent protection scope of this application.

Claims

1. A reagent extraction device, characterized in that, it includes: a reagent module for storing reagents; a sampling component for collecting the reagent with the reagent; a liquid level detection module for detecting the liquid level height of the reagent; a control module for: obtaining an initial liquid level height; based on the initial liquid level height, determining a first height and a second height; wherein, the first height is greater than the initial liquid level height, and the second height is less than the initial liquid level height; controlling the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height; in response to the third height being not less than the second height and not greater than the first height, controlling the needle of the reagent needle to move to a position below the third height to extract the reagent, and updating the initial liquid level height based on the third height.

2. The reagent extraction device according to claim 1, characterized in that, the updating the initial liquid level height based on the third height includes: in response to the third height being not greater than the sum of the initial liquid level height and a preset error threshold, updating the initial liquid level height to the difference between the third height and the reagent extraction amount height.

3. The reagent extraction device according to claim 2, characterized in that, the updating the initial liquid level height based on the third height further includes: in response to the third height being greater than the sum of the initial liquid level height and a preset error threshold, updating the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

4. The reagent extraction device according to any one of claims 1 to 3, characterized in that, after controlling the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height, the control module is further used for: in response to the third height being greater than the first height, controlling the needle of the reagent needle to move to a position below the second height to extract the reagent, and updating the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

5. The reagent extraction device according to claim 4, characterized in that, the in response to the third height being greater than the first height, controlling the needle of the reagent needle to move to a position below the second height to extract the reagent includes: in response to the third height being greater than the first height, controlling the liquid level detection module to re-detect the liquid level height of the reagent in the reagent module and update the third height; in response to the updated third height being greater than the first height, controlling the needle of the reagent needle to move to a position below the second height to extract the reagent.

6. The reagent extraction device according to any one of claims 1 to 3, characterized in that, the control module is further used for: In response to the reagent not being detected when the reagent needle moves down to the second height, control the needle of the reagent needle to move to a position below the second height to extract the reagent, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

7. The reagent extraction device according to any one of claims 1 to 3, wherein, the liquid level detection module is used to detect whether the needle of the reagent needle touches the reagent, obtain a touch detection result, and determine the liquid level height of the reagent based on the touch detection result; The controlling the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height includes: In response to the reagent not being detected when the reagent needle moves down to the second height, control the reagent needle to continue to move down until the liquid level detection module detects the reagent to obtain the third height before reaching the preset lowest liquid level; The control module is further configured to: If the reagent is still not detected when the reagent needle reaches the preset lowest liquid level, output an alarm indication for indicating that the liquid volume is empty; If the liquid level detection module detects the reagent before the reagent needle reaches the preset lowest liquid level to obtain the third height, control the reagent needle to move to a position below the third height to extract the reagent, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

8. The reagent extraction device according to any one of claims 1 to 3, wherein, The determining the first height and the second height based on the initial liquid level height includes: Adding the reagent extraction height to the initial liquid level height to obtain a target sum value; Multiplying the target sum value by a first preset ratio to obtain the first height; and / or, Subtracting the reagent extraction height from the initial liquid level height to obtain a target difference value; Multiplying the target difference value by a second preset ratio to obtain the second height; wherein, both the first preset ratio and the second preset ratio are greater than 0 and not greater than 1.

9. A reagent extraction method, wherein, It is applied to the reagent extraction device according to any one of claims 1 to 8; The reagent extraction method includes: Obtaining an initial liquid level height; Determining a first height and a second height based on the initial liquid level height; wherein, the first height is greater than the initial liquid level height, and the second height is less than the initial liquid level height; Controlling the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height; In response to the third height being not less than the second height and not greater than the first height, control the needle of the reagent needle to move to a position below the third height to extract the reagent, and update the initial liquid level height based on the third height.

10. A sample analyzer, wherein, It includes the reagent extraction device according to any one of claims 1 to 8.

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