Liquid conveying device and sample analyzer

Abstract

The invention discloses a liquid conveying device and a sample analyzer, the liquid conveying device comprises an injection assembly used for injecting liquid, the injection assembly comprises a first liquid injection needle and a power source, the power source is connected with the first liquid injection needle, and the power source is used for controlling the first liquid injection needle to inject the liquid; the control module is connected with the power source, and the control module is used for controlling the power source to suck back the first liquid injection needle in response to an instruction of switching the liquid conveying device to a preset state, so that the first liquid injection needle is filled with air; when the liquid conveying device is in a preset state, the first liquid injection needle is in a non-working state. Based on the mode, the reliability of the liquid conveying device can be improved.

Description

Technical Field

[0001] The present application relates to the technical field of sample detection, and particularly to a liquid delivery device and a sample analyzer. Background Art

[0002] In the prior art, during sample detection, it is usually necessary to use a liquid delivery device to deliver a sample liquid, a reagent, or other types of liquids to a designated position, such as a test tube, a reaction cup, or a reaction cell, etc., for corresponding processing, and finally obtain a result through sample detection.

[0003] The defect of the prior art is that after the liquid delivery device finishes delivering the liquid, if liquid delivery is not required in the short term, the liquid delivery device will be in a long-term static state. The liquid at the liquid outlet of the liquid delivery device (such as the needle opening of the injection needle) is prone to crystal precipitation due to contact with the outside air, resulting in water evaporation. As the crystals increase, the crystals will block the liquid outlet to form a clogging phenomenon, so that the liquid delivery device cannot normally deliver the liquid. The occurrence of this clogging phenomenon may even cause the pipeline inside the liquid delivery device to burst. Therefore, the reliability of the existing liquid delivery device is relatively low. Summary of the Invention

[0004] The main technical problem to be solved by the present application is how to improve the reliability of the liquid delivery device.

[0005] To solve the above technical problem, the first technical solution adopted by the present application is: a liquid delivery device, comprising: an injection assembly for injecting liquid, the injection assembly includes a first injection needle and a power source, the power source is connected to the first injection needle, and the power source is used to control the first injection needle to inject liquid; a control module, the control module is connected to the power source, and the control module is used to: in response to an instruction to switch the liquid delivery device to a preset state, control the power source to perform a suction action on the first injection needle so that the first injection needle is filled with air; when the liquid delivery device is in the preset state, the first injection needle is in a non-operating state.

[0006] Wherein, the injection assembly further includes a first switching valve, the first switching valve is respectively connected to the first injection needle and the power source; controlling the power source to perform a suction action on the first injection needle so that the first injection needle is filled with air includes: controlling the power source to perform a suction action on the first injection needle so that the liquid level is located in the liquid path between the first injection needle and the first switching valve.

[0007] Wherein, in the liquid path between the first injection needle and the first switching valve, the liquid path length between the liquid level and the first injection needle is greater than the liquid path length between the liquid level and the first switching valve.

[0008] Among them, the injection assembly also includes a second injection needle, a second switch valve and a three-way joint. The first switch valve is respectively connected to the first injection needle and the first opening of the three-way joint, the second switch valve is respectively connected to the second injection needle and the second opening of the three-way joint, and the power source is connected to the third opening of the three-way joint.

[0009] Among them, in response to the instruction to switch the liquid delivery device to a preset state, the power source is controlled to perform a back-sucking action on the first injection needle so that the first injection needle is filled with air, including: in response to the instruction to switch the liquid delivery device to a preset state, the power source is controlled to perform a back-sucking action on the first injection needle so that the liquid level is located in the liquid path between the first injection needle and the first switch valve, and the power source is controlled to perform a back-sucking action on the second injection needle so that the liquid level is located in the liquid path between the second injection needle and the second switch valve.

[0010] Among them, the control module is also used to: respond to the power-on indication after the liquid delivery device is abnormally shut down, and the duration of the abnormal shutdown of the liquid delivery device is greater than the first preset duration threshold, then output an alarm prompt, and the alarm prompt is used to indicate that there is a risk of blockage in the first injection needle; in response to the release instruction of the alarm indication, control the power source to push the first injection needle so that the first injection needle is filled with liquid.

[0011] Among them, the control module is also used to: in response to the liquid delivery device being in the on state and the injection component being inactive for a period of time greater than a second preset time threshold, generate an instruction to switch the liquid delivery device to a standby state; in response to the instruction to switch the liquid delivery device to the standby state, control the power source to perform a back suction action on the first injection needle so that the first injection needle is filled with air.

[0012] Among them, the injection component also includes a reagent storage module and a first three-way valve, the first branch port of the first three-way valve is connected to the first injection needle, the second branch port of the first three-way valve is connected to the reagent storage module, and the common port of the first three-way valve is connected to the power source.

[0013] In order to solve the above-mentioned technical problems, the second technical solution adopted in the present application is: a sample analyzer, comprising a detection device and the above-mentioned liquid delivery device; the liquid delivery device is used to control the power source to push the first injection needle so that the first injection needle injects the liquid into the reaction pool of the detection device; the detection device is used to perform sample detection based on the liquid in the reaction pool; and / or, the liquid delivery device is used to control the power source to perform a back suction action on the first injection needle so that the first injection needle inhales the sample and / or reagent, and controls the power source to push the first injection needle so that the first injection needle injects the sample and / or reagent into the reaction pool of the detection device; the detection device is used to perform sample detection based on the sample and / or reagent in the reaction pool.

[0014] To solve the above technical problems, the third technical solution adopted by this application is: a control method for a sample analyzer, which is applied to a sample analyzer. The sample analyzer includes an injection assembly, and the injection assembly includes a first liquid injection needle and a power source; the control method includes: in response to an instruction to switch the sample analyzer to a preset state, controlling the power source to perform a suction action on the first liquid injection needle so that the first liquid injection needle is filled with air; switching the sample analyzer to the preset state; wherein, when the sample analyzer is in the preset state, the first liquid injection needle is in a non-working state.

[0015] The beneficial effect of this application is that: different from the prior art, in the technical solution of this application, in the injection assembly, the power source is connected to the first liquid injection needle, and the control module can be used to control the power source to push or suck the liquid in the first liquid injection needle and its related liquid path. The preset state can specifically be the state of the liquid delivery device when the first liquid injection needle is in a non-working state. The control module can specifically be used to control the power source to suck the liquid in the first liquid injection needle when receiving an instruction to switch the liquid delivery device to the preset state, so that the first liquid injection needle is filled with air, reducing the possibility of the phenomenon that the water analysis volatilizes and crystallizes to block the needle port due to the contact between the liquid at the needle port of the first liquid injection needle and the outside air, and further reducing the possibility of the liquid delivery device being damaged due to this hole-blocking phenomenon, improving the reliability of the liquid delivery device. Description of the Drawings

[0016] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the following drawings are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0017] Figure 1 It is a schematic structural diagram of an embodiment of the liquid delivery device of this application;

[0018] Figure 2 It is a schematic structural diagram of an embodiment of the sample analyzer of this application;

[0019] Figure 3 It is a schematic flowchart of an embodiment of the control method of the sample analyzer of this application.

[0020] Wherein: the first liquid injection needle 11, the second liquid injection needle 12, the first switching valve 13, the second switching valve 14, the power source 15, the three-way joint 16, the first three-way valve 17, the reagent storage module 18, the first reagent storage unit 181, the second reagent storage unit 182, the second three-way valve 19, the sample analyzer 20, the liquid delivery device 10. Detailed Embodiments

[0021] The present application will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be specifically noted that the following embodiments are only used to illustrate the present application, but do not limit the scope of the present application. Similarly, the following embodiments are only partial embodiments of the present application rather than all embodiments. All other embodiments obtained by those of ordinary skill in the art without creative efforts fall within the scope of protection of the present application.

[0022] Referring to "embodiments" herein means that the specific features, structures, or characteristics described in connection with the embodiments may be included in at least one embodiment of the present application. The phrase appearing in various positions in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments. Those skilled in the art will explicitly and implicitly understand that the embodiments described herein can be combined with other embodiments.

[0023] In the description of the present application, it should be noted that unless otherwise clearly specified and defined, the terms "installed", "set", "connected", and "coupled" should be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or an integral connection; it may be a mechanical connection or an electrical connection; it may be directly connected, or indirectly connected through an intermediate medium. For those of ordinary skill in the art, the specific meaning of the above terms in the present application can be understood according to specific circumstances.

[0024] The present application provides a liquid delivery device. Refer to Figure 1 , Figure 1 which is a schematic structural diagram of an embodiment of the liquid delivery device of the present application. As shown in Figure 1 , the liquid delivery device includes an injection assembly and a control module. Among them, the injection assembly is used for injecting liquid, and the injection assembly includes a first injection needle 11 and a power source 15.

[0025] The power source 15 is connected to the first injection needle 11, and the power source 15 is used to control the first injection needle 11 to inject liquid. One end of the first injection needle 11 is used to output liquid, and the other end of the first injection needle 11 can be connected to the power source 15. The power source 15 can inject liquid (such as a sample or a reagent) into a corresponding container (such as a reaction tank) by pushing the liquid in the first injection needle 11, or can suck back the liquid in the first injection needle 11 to fill the first injection needle 11 with air, which can be specifically controlled according to actual needs.

[0026] The control module is connected to the power source 15, and the control module is used for:

[0027] In response to an instruction to switch the liquid delivery device to a preset state, the power source 15 is controlled to perform a sucking-back action on the first injection needle 11 to fill the first injection needle 11 with air.

[0028] Wherein, when the liquid delivery device is in a preset state, the first liquid injection needle 11 is in a non-operating state. The preset state is any one of a sleep state, a shutdown state, a standby state, and other states of the liquid delivery device when the first liquid injection needle 11 is in a non-operating state.

[0029] When the liquid delivery device is about to switch its state to a preset state, for example, it can be when the device is about to enter the sleep state or the shutdown state or the standby state from the powered-on state, or when the device is about to enter the powered-on state from the sleep state or the shutdown state or the standby state. The liquid delivery device can be detected to determine the working state that the liquid delivery device is about to enter.

[0030] In one example, after the liquid delivery device switches to the sleep state or the shutdown state or the standby state, its various components usually enter a state of long-term static rest. If there is liquid near the needle opening of the first liquid injection needle 11 at this time, the liquid is likely to volatilize and water analysis will precipitate crystals, that is, it is likely to form crystals and cause the phenomenon of blocked holes. Therefore, when the liquid delivery device is about to enter the sleep state or the shutdown state or the standby state, the first liquid injection needle 11 can be back-sucked to make the first liquid injection needle 11 filled with air, so that there is less liquid remaining near the needle opening of the first liquid injection needle 11, reducing the possibility of the occurrence of the blocked hole phenomenon, and further avoiding the possibility of damage to the liquid delivery device due to the blocked hole phenomenon, making the liquid delivery device highly reliable.

[0031] The power source 15 can specifically be a module with suction and discharge capabilities, such as a syringe or other types of suction and discharge modules.

[0032] Different from the prior art, in the technical solution of the present application, in the injection assembly, the power source is connected to the first liquid injection needle, and the control module can be used to control the power source to push or back-suck the liquid in the first liquid injection needle and its related liquid paths. The preset state can specifically be the state of the liquid delivery device when the first liquid injection needle is in a non-operating state. The control module can specifically be used to control the power source to back-suck the liquid in the first liquid injection needle when receiving an instruction to switch the liquid delivery device to the preset state, so that the first liquid injection needle is filled with air, reducing the possibility of the phenomenon that the liquid volatilizes and water analysis precipitates crystals to block the needle opening when the liquid in the first liquid injection needle contacts the outside air at the needle opening, and further reducing the possibility of damage to the liquid delivery device due to this blocked hole phenomenon, improving the reliability of the liquid delivery device.

[0033] In one embodiment, as Figure 1 shown, the injection assembly further includes a first switching valve 13, and the first switching valve 13 is respectively connected to the first liquid injection needle 11 and the power source 15.

[0034] Controlling the power source 15 to perform a sucking-back action on the first liquid injection needle 11 so that the first liquid injection needle 11 is filled with air includes:

[0035] Controlling the power source 15 to perform a sucking-back action on the first liquid injection needle 11 so that the liquid level is located in the liquid path between the first liquid injection needle 11 and the first switching valve 13.

[0036] Specifically, the liquid level is specifically the interface between the liquid and the air in the liquid path. One side of the liquid level is air, and the other side is liquid.

[0037] The first switching valve 13 is respectively connected to the first liquid injection needle 11 and the power source 15 through corresponding liquid paths. When it is detected that the liquid delivery device is about to switch from the startup state to the preset state, the power source 15 can be controlled to suck back the liquid in the first liquid injection needle 11, so that the liquid level retreats from near the needle opening of the first liquid injection needle 11 to the liquid path between the first liquid injection needle 11 and the first switching valve 13.

[0038] It should be noted that if the liquid level retreats to the liquid path between the first switching valve 13 and the power source 15, it is easy for the liquid remaining on the first switching valve 13 to volatilize moisture and form crystals due to contact with air. These crystals can easily affect the normal operation of the first switching valve 13 and cause damage. In addition, it is also easy for the first switching valve 13 to introduce air bubbles when being refilled with liquid, thereby reducing the accuracy of subsequent liquid injection through the first liquid injection needle 11.

[0039] Based on the above method, the first liquid injection needle 11 can be filled with air without a large amount of liquid, minimizing the possibility of crystal formation and hole blockage at the needle opening of the first liquid injection needle 11. At the same time, it can also reduce the possibility of crystal formation or air bubbles in the first switching valve 13 affecting its normal operation, further improving the reliability of the liquid delivery device.

[0040] Optionally, in the liquid path between the first liquid injection needle 11 and the first switching valve 13, the length of the liquid path between the liquid level and the first liquid injection needle 11 is greater than the length of the liquid path between the liquid level and the first switching valve 13.

[0041] Specifically, the farther the distance between the liquid level and the needle opening of the first liquid injection needle 11, the slower the crystallization rate of the liquid due to water evaporation. And when the liquid level is in the liquid path, even if crystals precipitate, they will adhere to the inner surface of the liquid path and will not cause hole blockage.

[0042] Based on the above method, while making the liquid level in the liquid path between the first liquid injection needle 11 and the first switching valve 13, the liquid level of the liquid is made as far away from the needle opening of the first liquid injection needle 11 as possible, thereby reducing the amount of crystallization on the inner surface of the liquid path, and further reducing the possibility of clogging the hole or the liquid path due to crystallization, and further improving the reliability of the liquid delivery device.

[0043] Optionally, as Figure 1 shown, the injection assembly further includes a second liquid injection needle 12, a second switching valve 14 and a tee joint 16. The first switching valve 13 is respectively connected to the first liquid injection needle 11 and the first opening of the tee joint 16. The second switching valve 14 is respectively connected to the second liquid injection needle 12 and the second opening of the tee joint 16. The power source 15 is connected to the third opening of the tee joint 16.

[0044] Specifically, the power source 15, the first liquid injection needle 11 and the second liquid injection needle 12 can be respectively connected through the tee joint 16. The first switching valve 13 provided on the liquid path between the first liquid injection needle 11 and the power source 15 can control whether the liquid can flow through this liquid path, and the second switching valve 14 provided on the liquid path between the second liquid injection needle 12 and the power source 15 can control whether the liquid can flow through this liquid path.

[0045] In one example, the first switching valve 13 and the second switching valve 14 can be controlled to be both opened, and then the power source 15 can be controlled to perform a liquid injection operation on the first liquid injection needle 11 and the second liquid injection needle 12 at the same time, so that the liquid can flow out from the needle openings of the first liquid injection needle 11 and the second liquid injection needle 12 at the same time, and be respectively injected into different reaction pools at the same time.

[0046] In another example, the first switching valve 13 and the second switching valve 14 can be controlled to be alternately opened and closed. For example, when the first switching valve 13 is controlled to be opened and the second switching valve 14 is controlled to be closed, the power source 15 can be controlled to perform a liquid injection operation on the first liquid injection needle 11 to inject the liquid into the reaction pool at the first moment. Then, when the first switching valve 13 is controlled to be closed and the second switching valve 14 is controlled to be opened, the power source 15 can be controlled to perform a liquid injection operation on the second liquid injection needle 12 to inject the liquid into the reaction pool at the second moment. In summary, the liquid can be injected into the reaction pool at two successive moments respectively.

[0047] The above two liquid injection methods can be respectively realized by controlling the first switching valve 13 and the second switching valve 14. In addition, other types of liquid injection methods can also be realized by controlling the first switching valve 13 and the second switching valve 14, which are not limited here.

[0048] Based on the above method, by controlling the opening and closing of the first switching valve 13 and the second switching valve 14, liquid can flow through the liquid paths corresponding to the first liquid injection needle 11 and / or the second liquid injection needle 12 respectively, thereby meeting the user's requirements for various types of liquid injection methods and improving the flexibility of use of the liquid delivery device.

[0049] Further, as Figure 1 shown, in response to an indication to switch the liquid delivery device to a preset state, the power source 15 is controlled to perform a suction action on the first liquid injection needle 11 to fill the first liquid injection needle 11 with air, including:

[0050] In response to an indication to switch the liquid delivery device to a preset state, the power source 15 is controlled to perform a suction action on the first liquid injection needle 11 to make the liquid level located in the liquid path between the first liquid injection needle 11 and the first switching valve 13, and the power source 15 is controlled to perform a suction action on the second liquid injection needle 12 to make the liquid level located in the liquid path between the second liquid injection needle 12 and the second switching valve 14.

[0051] Specifically, the first switching valve 13 is respectively connected to the first liquid injection needle 11 and the power source 15 through corresponding liquid paths. When it is detected that the liquid delivery device is about to switch from the powered-on state to the preset state, the power source 15 can be controlled to suck back the liquid in the first liquid injection needle 11, so that the liquid level retreats from near the needle tip of the first liquid injection needle 11 to the liquid path between the first liquid injection needle 11 and the first switching valve 13. Similarly, the second switching valve 14 is respectively connected to the second liquid injection needle 12 and the power source 15 through corresponding liquid paths. When it is detected that the liquid delivery device is about to switch from the powered-on state to the preset state, the power source 15 can be controlled to suck back the liquid in the second liquid injection needle 12, so that the liquid level retreats from near the needle tip of the second liquid injection needle 12 to the liquid path between the second liquid injection needle 12 and the second switching valve 14.

[0052] It should be noted that if the liquid level retreats to the liquid path between the first switching valve 13 and the power source 15, it is easy for the liquid remaining on the first switching valve 13 to volatilize moisture and form crystals due to contact with air, and the crystals are likely to affect the normal operation of the first switching valve 13, thereby causing damage. Similarly, if the liquid level retreats to the liquid path between the second switching valve 14 and the power source 15, it is easy for the liquid remaining on the second switching valve 14 to volatilize moisture and form crystals due to contact with air, and the crystals are likely to affect the normal operation of the second switching valve 14, thereby causing damage.

[0053] Based on the above method, it is possible to fill the first liquid injection needle 11 and the second liquid injection needle 12 with air and there is no large amount of liquid, which reduces the possibility of crystallization and blockage of the needle ports of the first liquid injection needle 11 and the second liquid injection needle 12 as much as possible. At the same time, it can also reduce the possibility of crystallization of the first switching valve 13 and the second switching valve 14 and affect their normal operation, further improving the reliability of the liquid delivery device.

[0054] Furthermore, as Figure 1 shown, controlling the power source 15 to perform a suction action on the first liquid injection needle 11 so that the liquid level is in the liquid path between the first liquid injection needle 11 and the first switching valve 13, and controlling the power source 15 to perform a suction action on the second liquid injection needle 12 so that the liquid level is in the liquid path between the second liquid injection needle 12 and the second switching valve 14, includes:

[0055] Controlling the first switching valve 13 to open and the second switching valve 14 to close, and controlling the power source 15 to perform a suction action on the first liquid injection needle 11 so that the liquid level is in the liquid path between the first liquid injection needle 11 and the first switching valve 13.

[0056] Controlling the first switching valve 13 to close and the second switching valve 14 to open, and controlling the power source 15 to perform a suction action on the second liquid injection needle 12 so that the liquid level is in the liquid path between the second liquid injection needle 12 and the second switching valve 14.

[0057] Specifically, before controlling the power source 15 to perform a suction action on the first liquid injection needle 11 so that the liquid level is in the liquid path between the first liquid injection needle 11 and the first switching valve 13, the first switching valve 13 can be opened and the second switching valve 14 can be closed.

[0058] After controlling the power source 15 to perform a suction action on the first liquid injection needle 11 so that the liquid level is in the liquid path between the first liquid injection needle 11 and the first switching valve 13, the first switching valve 13 is closed and the second switching valve 14 is opened, and the power source 15 is controlled to perform a suction action on the second liquid injection needle 12 so that the liquid level is in the liquid path between the second liquid injection needle 12 and the second switching valve 14.

[0059] Finally, the first switching valve 13 and the second switching valve 14 are closed to complete the suction action.

[0060] Based on the above method, by reasonably controlling the first switching valve 13 and the second switching valve 14, it is also possible to avoid the situation where the suction actions of each liquid injection needle affect each other, resulting in excessive or insufficient suction, further improving the reliability of the liquid delivery device.

[0061] In one example, when the liquid delivery device is in the powered-on state and a liquid injection operation is required, the first switching valve 13 can be controlled to open and the second switching valve 14 to close, and the power source 15 can be controlled to perform a liquid injection operation on the first injection needle 11, so that the liquid flows out of the first injection needle 11 and is injected into the corresponding container. After that, the first switching valve 13 is controlled to close and the second switching valve 14 to open, and the power source 15 is controlled to perform a liquid injection operation on the second injection needle 12, so that the liquid flows out of the first injection needle 11 and is injected into the corresponding container. Or,

[0062] When the liquid delivery device is in the powered-on state and a liquid injection operation is required, the first switching valve 13 and the second switching valve 14 can both be controlled to open, and the power source 15 can be controlled to perform a liquid injection operation on the first injection needle 11, so that the liquid flows out of the first injection needle 11 and is injected into the corresponding container. Moreover, the first switching valve 13 is controlled to close and the second switching valve 14 to open, and the power source 15 is controlled to perform a liquid injection operation on the second injection needle 12, so that the liquid flows out of the first injection needle 11 and is injected into the corresponding container.

[0063] Based on the above method, by controlling the first switching valve 13 and the second switching valve 14, the first injection needle 11 and the second injection needle 12 can perform liquid injection operations successively or simultaneously, which can be specifically determined according to actual needs and is not limited here.

[0064] In one embodiment, the control module is further configured to:

[0065] In response to the working state being updated from the preset state to the powered-on state, the power source 15 is controlled to perform a pushing operation on the first injection needle 11, so that the first injection needle 11 is filled with liquid.

[0066] Specifically, when the working state of the liquid delivery device is switched from the preset state to the powered-on state, it is necessary to first perform a pushing operation on the first injection needle 11 to fill the first injection needle 11 with liquid, and then control the power source 15 to further perform a pushing operation to achieve liquid injection.

[0067] Based on the above method, after the first injection needle 11 is filled with liquid, the corresponding liquid injection operation can be executed in response, reducing the possibility of excessive bubbles in the injected liquid caused by performing liquid injection when the first injection needle 11 is not filled with liquid, and thus improving the reliability of sample detection based on the injected liquid.

[0068] In one embodiment, the control module is further configured to:

[0069] In response to the power-on instruction after the abnormal shutdown of the liquid delivery device, and when the duration of the abnormal shutdown of the liquid delivery device is greater than the first preset duration threshold, an alarm prompt is output. Among them, the alarm prompt is used to prompt that there is a risk of blockage in the first injection needle 11.

[0070] In response to the instruction to release the alarm indication, the power source is controlled to push the first injection needle 11 so that the first injection needle 11 is filled with liquid.

[0071] Specifically, in practice, the liquid delivery device may accidentally enter the shutdown state due to power outage or other abnormalities. Since the control module does not control the first injection needle 11 to perform the above-mentioned suction action when entering the shutdown state due to the abnormal shutdown, the first injection needle 11 is in a state of being stationary with liquid in the shutdown state entered due to the abnormal shutdown. If the stationary time with liquid is long enough, the needle tip of the first injection needle 11 may be blocked due to the evaporation and crystallization of water in the liquid.

[0072] Therefore, when it is detected that the working state of the liquid delivery device is the power-on state after an abnormal shutdown, and the abnormal shutdown time of the liquid delivery device is greater than the first preset time threshold, an alarm prompt can be output to prompt the user to check whether there is a blockage at the needle port. If so, corresponding maintenance processing is required as soon as possible to restore the normal infusion capacity of the liquid delivery device. The first preset time threshold can be 10 days, 20 days, 30 days and any other time length, depending on actual needs, and is not limited here.

[0073] After the user has finished the inspection, the liquid delivery device can be controlled to generate a release command for the alarm warning. After receiving the release command, the liquid delivery device can control the power source to push the first injection needle 11 so that the first injection needle 11 that was originally filled with air is refilled with liquid and enters a state where the injection action can be performed at any time, in preparation for injection.

[0074] Based on the above method, when an abnormality occurs and the shutdown time is too long, the user can be warned, so as to reduce the possibility of damage to the liquid delivery device due to hole blockage when the liquid delivery device restarts after a long abnormal shutdown, thereby improving the reliability of the liquid delivery device.

[0075] In one embodiment, the control module is further configured to:

[0076] In response to the liquid delivery device being in the on state and the injection component being inactive for a period of time greater than a second preset time threshold, an instruction to switch the liquid delivery device to the standby state is generated.

[0077] In response to the instruction to switch the liquid delivery device to the standby state, the power source 15 is controlled to perform a back suction action on the first injection needle 11 so that the first injection needle 11 is filled with air.

[0078] Specifically, when the liquid delivery device is in the powered-on state, but none of its components (such as the power source 15) have performed any actions, and the duration of this non-execution of any actions is greater than the second preset duration threshold, the working state of the liquid delivery device can be switched from the powered-on state to the standby state. Subsequently, when it is detected that the working state of the liquid delivery device is the standby state, the above-mentioned back-suction action can be performed to fill the first liquid injection needle 11 with air.

[0079] The second preset duration threshold can specifically be half an hour, one hour, three hours, or any other duration, which is specifically determined according to actual requirements and is not limited herein.

[0080] Based on the above method, the possibility of the phenomenon that the liquid volatilizes and the water analysis crystallizes to block the needle opening due to the contact between the liquid at the needle opening of the first liquid injection needle and the external air can be reduced. Furthermore, the possibility of the liquid delivery device being damaged due to this needle blockage phenomenon can be reduced, improving the reliability of the liquid delivery device.

[0081] In one embodiment, as Figure 1 shown, the injection assembly further includes a reagent storage module 18 and a first three-way valve 17. The first branch port of the first three-way valve 17 is connected to the first liquid injection needle 11, the second branch port of the first three-way valve 17 is connected to the reagent storage module 18, and the common port of the first three-way valve 17 is connected to the power source 15.

[0082] Specifically, when the control module controls the first three-way valve 17 to connect its common port to its second branch port, it controls the power source 15 to suck the reagent from the reagent storage module 18. After that, it controls the first three-way valve 17 to connect its common port to its first branch port, and then controls the power source 15 to spit out the reagent from the first liquid injection needle 11 and inject it into the corresponding container. Finally, it controls the first three-way valve 17 to connect its common port to its second branch port to complete the reset of the first three-way valve 17.

[0083] Based on the above method, by reasonably controlling the first three-way valve 17, it is possible to obtain the reagent from the reagent storage module 18 and then transport it to the corresponding container.

[0084] Optionally, as Figure 1 shown, the reagent storage module 18 may include a first reagent storage unit 181 and a second reagent storage unit 182, and the injection assembly may further include a second three-way valve 19.

[0085] The common port of the second three-way valve 19 is connected to the second branch port of the first three-way valve 17. The first branch port of the second three-way valve 19 is connected to the first reagent storage unit 181, and the second branch port of the second three-way valve 19 is connected to the second reagent storage unit 182.

[0086] The reagents stored in the first reagent storage unit 181 and the second reagent storage unit 182 can be of different types or the same type, which is not limited here.

[0087] Based on the above method, by setting two reagent storage units and the second three-way valve 19, when any one of the reagents stored in the first reagent storage unit 181 and the second reagent storage unit 182 is needed, the second three-way valve 19 can be controlled to conduct its common port and the corresponding branch port for liquid suction, improving the flexibility of use of the liquid delivery device.

[0088] This application also proposes a sample analyzer. Refer to Figure 2 , Figure 2 is a schematic structural diagram of an embodiment of the sample analyzer of this application. As Figure 2 shown, the sample analyzer 20 includes a liquid delivery device 10. The liquid delivery device 10 can be the liquid delivery device described in any of the previous embodiments, which will not be elaborated here.

[0089] The liquid delivery device is used to control the power source 15 to perform a propulsion action on the first injection needle 11, so that the first injection needle 11 injects liquid into the reaction container of the detection device.

[0090] The detection device is used to perform sample detection based on the liquid in the reaction container.

[0091] and / or,

[0092] The liquid delivery device is used to control the power source 15 to perform a back-suction action on the first injection needle 11, so that the first injection needle 11 sucks the sample and / or reagent, and controls the power source 15 to perform a propulsion action on the first injection needle 11, so that the first injection needle 11 injects the sample and / or reagent into the reaction container of the detection device;

[0093] and / or

[0094] The liquid delivery device is used to control the power source to perform a propulsion action on the first injection needle, so that the first injection needle injects the liquid into the reaction container of the detection device to clean the reaction container.

[0095] The detection device is used to perform sample detection based on the sample and / or reagent in the reaction container.

[0096] Optionally, the reaction container can refer to various components such as test tubes, reaction cups, reaction pools, etc. that can be used to hold liquids. Specifically, the liquid delivery device can be a device used to inject any kind of liquid into the corresponding container through an injection needle. For example, it can be used to inject a diluent into the reaction container through the first injection needle 11 for use when the detection device performs sample detection; it can also inject a cleaning liquid into the reaction container through the first injection needle to clean the reaction container.

[0097] In addition, the liquid delivery device can also be a part of the sampling device. By inserting the needle tip of the first liquid injection needle 11 into the sample / reagent to be collected and controlling the power source 15 to perform a suction action, the sample / reagent to be collected can be sucked into the first liquid injection needle 11. Subsequently, the sample / reagent collected in the first liquid injection needle 11 can be injected into the reaction container for use by the detection device during sample detection.

[0098] In one embodiment, the above sample analyzer is an immunoassay analyzer, and the immunoassay analyzer includes the liquid delivery device described in any of the previous embodiments. The liquid delivery device can include one or more liquid injection needles.

[0099] The immunoassay analyzer includes a detection device. The liquid delivery device is used to control the power source to perform a propulsion action on the first liquid injection needle, so that the first liquid injection needle injects the detection base liquid into the reaction cup, enabling the detection device to perform sample detection on the liquid in the reaction cup.

[0100] Optionally, the immunoassay analyzer includes a magnetic separation component for loading the reaction cup and performing magnetic separation cleaning on the reaction cup; the liquid delivery device is used to control the power source to perform a propulsion action on the first liquid injection needle, so that the first liquid injection needle injects the cleaning liquid into the reaction cup of the magnetic separation component for magnetic separation cleaning.

[0101] Optionally, in one embodiment, different from the liquid injection needle used for injecting multiple liquids and requiring cleaning after each liquid injection, the liquid injection needle provided by the technical solution of the present application is used for injecting only one liquid at least in one detection process and does not require cleaning of the liquid injection needle after each liquid injection. When the liquid delivery device is in the powered-on state, the liquid injection needle remains filled with liquid, with high liquid injection efficiency and no liquid path contamination; and when receiving an instruction to switch the liquid delivery device to a preset state through the technology of the present application, the power source is controlled to aspirate the liquid in the first liquid injection needle, so that the first liquid injection needle is filled with air, which can reduce the possibility of crystal precipitation caused by the volatilization of water analysis at the needle tip of the liquid injection needle due to the liquid injection needle being filled with liquid and the contact with the outside air, thereby reducing the possibility of damage to the liquid delivery device caused by this plugging phenomenon and improving the reliability of the liquid delivery device.

[0102] It should be noted that the switching valve and the three-way valve mentioned in the present application can specifically be solenoid valves, or other types of valves with switching or three-way capabilities, which are not limited herein.

[0103] Different from the prior art, in the technical solution of the present application, in the injection assembly, the power source is connected to the first liquid injection needle, and the control module can be used to control the power source to push or suck back the liquid in the first liquid injection needle and its related liquid path. The preset state can specifically be the state of the liquid delivery device when the first liquid injection needle is in a non-working state. The control module can specifically be used to control the power source to suck back the liquid in the first liquid injection needle when receiving an instruction to switch the liquid delivery device to the preset state, so that the first liquid injection needle is filled with air, reducing the possibility of the phenomenon that the water volatilizes and crystallizes to block the needle opening due to the contact between the liquid at the needle opening of the first liquid injection needle and the external air, thereby reducing the possibility of damage to the liquid delivery device caused by this hole-blocking phenomenon and improving the reliability of the liquid delivery device.

[0104] The present application also proposes a control method for a sample analyzer. Refer to Figure 3 , Figure 3 FIG. is a schematic flowchart of an embodiment of the control method for the sample analyzer of the present application. The control method for the sample analyzer is applied to the sample analyzer. The sample analyzer includes an injection assembly, and the injection assembly includes a first liquid injection needle 11 and a power source 15. In one example, the sample analyzer may include the liquid delivery device or the injection assembly described in any of the foregoing embodiments, which will not be elaborated herein.

[0105] As Figure 3 shown, the control method includes:

[0106] Step S11: In response to an instruction to switch the sample analyzer to the preset state, control the power source 15 to perform a sucking-back action on the first liquid injection needle 11 so that the first liquid injection needle 11 is filled with air.

[0107] Step S12: Switch the sample analyzer to the preset state.

[0108] Wherein, when the sample analyzer is in the preset state, the first liquid injection needle is in a non-working state.

[0109] Different from the prior art, in the technical solution of the present application, in the injection assembly, the power source is connected to the first liquid injection needle, and the control module can be used to control the power source to push or suck back the liquid in the first liquid injection needle and its related liquid path. The preset state can specifically be the state of the liquid delivery device when the first liquid injection needle is in a non-working state. The control module can specifically be used to control the power source to suck back the liquid in the first liquid injection needle when receiving an instruction to switch the liquid delivery device to the preset state, so that the first liquid injection needle is filled with air, reducing the possibility of the phenomenon that the water volatilizes and crystallizes to block the needle opening due to the contact between the liquid at the needle opening of the first liquid injection needle and the external air, thereby reducing the possibility of damage to the liquid delivery device caused by this hole-blocking phenomenon and improving the reliability of the liquid delivery device.

[0110] In the description of the present application, the description with reference to terms such as "one embodiment", "some embodiments", "example", "specific example", or "some examples" means that the specific features, structures, materials, or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, without contradiction, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of different embodiments or examples.

[0111] In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present application, "a plurality of" means at least two, such as two, three, etc., unless otherwise specifically defined.

[0112] Any process or method description shown in the flowchart or described in other ways herein may be understood to represent a module, segment, or portion of code including one or more executable instructions for implementing a specific logical function or process, and the scope of the preferred embodiments of the present application includes additional implementations, where the functions may be executed in a manner that is not shown or discussed, including in a substantially simultaneous manner according to the functions involved or in a reverse order, which should be understood by those skilled in the art to which the embodiments of the present application pertain.

[0113] The logic and / or steps represented in the flowchart or otherwise described herein can be considered, for example, a definitional sequence of executable instructions for implementing logical functions, which can be embodied in any computer-readable medium for use by or in connection with an instruction execution system, apparatus, or device (which can be a personal computer, a server, a network device, or other systems that can fetch and execute instructions from the instruction execution system, apparatus, or device). For the purposes of this specification, a "computer-readable medium" can be any device that can contain, store, communicate, propagate, or transport a program for use by or in connection with an instruction execution system, apparatus, or device. More specific examples (a non-exhaustive list) of the computer-readable medium include the following: an electrical connection portion with one or more wirings (electronic device), a portable computer diskette (magnetic device), a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber device, and a portable compact disc read-only memory (CDROM). Additionally, the computer-readable medium can even be paper or other suitable media on which the program can be printed, as the program can be obtained electronically, for example, by optically scanning the paper or other media, followed by editing, interpretation, or otherwise appropriate processing if necessary, and then storing it in a computer memory.

[0114] The above description is only for the implementation manners of this application and does not limit the patent scope of this application. Any equivalent structure or equivalent process transformation made by using the content of the specification and drawings of this application, or directly or indirectly applied in other related technical fields, shall be included in the patent protection scope of this application by the same token.

Claims

1. A liquid delivery device, characterized in that, comprising: an injection assembly for injecting liquid, the injection assembly including a first liquid injection needle and a power source, the power source being connected to the first liquid injection needle, and the power source being used to control the first liquid injection needle to inject the liquid; a control module, the control module being connected to the power source, and the control module being used for: responding to an indication to switch the liquid delivery device to a preset state, and then controlling the power source to perform a suction action on the first liquid injection needle so that the first liquid injection needle is filled with air; wherein, when the liquid delivery device is in the preset state, the first liquid injection needle is in a non-operating state.

2. The liquid delivery device according to claim 1, characterized in that, the injection assembly further includes a first switching valve, and the first switching valve is respectively connected to the first liquid injection needle and the power source; the controlling the power source to perform a suction action on the first liquid injection needle so that the first liquid injection needle is filled with air includes: controlling the power source to perform a suction action on the first liquid injection needle so that the liquid level of the liquid is located in the liquid path between the first liquid injection needle and the first switching valve.

3. The liquid delivery device according to claim 2, characterized in that, in the liquid path between the first liquid injection needle and the first switching valve, the liquid path length between the liquid level of the liquid and the first liquid injection needle is greater than the liquid path length between the liquid level of the liquid and the first switching valve.

4. The liquid delivery device according to claim 2 or 3, characterized in that, the injection assembly further includes a second liquid injection needle, a second switching valve and a three-way joint, the first switching valve is respectively connected to the first liquid injection needle and the first opening of the three-way joint, the second switching valve is respectively connected to the second liquid injection needle and the second opening of the three-way joint, and the power source is connected to the third opening of the three-way joint.

5. The liquid delivery device according to claim 4, characterized in that, the responding to an indication to switch the liquid delivery device to a preset state, and then controlling the power source to perform a suction action on the first liquid injection needle so that the first liquid injection needle is filled with air includes: responding to an indication to switch the liquid delivery device to a preset state, and then controlling the power source to perform a suction action on the first liquid injection needle so that the liquid level of the liquid is located in the liquid path between the first liquid injection needle and the first switching valve, and controlling the power source to perform a suction action on the second liquid injection needle so that the liquid level of the liquid is located in the liquid path between the second liquid injection needle and the second switching valve.

6. The liquid delivery device according to any one of claims 1 to 3, characterized in that, the control module is further used for: responding to a power-on indication after the liquid delivery device is abnormally shut down, and when the duration of the abnormal shutdown of the liquid delivery device is greater than a first preset duration threshold, outputting an alarm prompt, and the alarm prompt is used to prompt that there is a risk of clogging of the first liquid injection needle; In response to a release instruction for the alarm indication, the power source is controlled to push the first injection needle so that the first injection needle is filled with liquid.

7. The liquid delivery device according to any one of claims 1 to 3, It is characterized in that The control module is also used for: In response to the liquid delivery device being in the on state and the injection assembly being inactive for a time period greater than a second preset time threshold, generating an instruction to switch the liquid delivery device to a standby state; In response to the instruction to switch the liquid delivery device to the standby state, the power source is controlled to perform a back suction action on the first injection needle so that the first injection needle is filled with air.

8. The liquid delivery device according to any one of claims 1 to 3, It is characterized in that The injection assembly also includes a reagent storage module and a first three-way valve, wherein the first branch port of the first three-way valve is connected to the first injection needle, the second branch port of the first three-way valve is connected to the reagent storage module, and the common port of the first three-way valve is connected to the power source.

9. A sample analyzer, It is characterized in that comprising a detection device and a liquid delivery device as claimed in any one of claims 1 to 8; The liquid delivery device is used to control the power source to push the first injection needle, so that the first injection needle injects the liquid into the reaction container of the detection device; The detection device is used to perform sample detection based on the liquid in the reaction container; and / or, The liquid delivery device is used to control the power source to perform a back suction action on the first injection needle so that the first injection needle can absorb the sample and / or the reagent, and control the power source to perform a propulsion action on the first injection needle so that the first injection needle can inject the sample and / or the reagent into the reaction container of the detection device; The detection device is used to perform sample detection based on the sample and / or the reagent in the reaction container; and / or The liquid delivery device is used to control the power source to push the first injection needle so that the first injection needle injects the liquid into the reaction container of the detection device to clean the reaction container.

10. A control method for a sample analyzer, It is characterized in that Applied to a sample analyzer, the sample analyzer comprises an injection assembly, the injection assembly comprises a first injection needle and a power source; The control method comprises: In response to an instruction to switch the sample analyzer to a preset state, the power source is controlled to perform a back suction action on the first injection needle so that the first injection needle is filled with air; Switching the sample analyzer to the preset state; Wherein, when the sample analyzer is in the preset state, the first injection needle is in a non-working state.

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